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https://www.readbyqxmd.com/read/29338002/the-associations-between-adult-body-composition-and-abdominal-adiposity-outcomes-and-relative-weight-gain-and-linear-growth-from-birth-to-age-22-in-the-birth-to-twenty-plus-cohort-south-africa
#1
Alessandra Prioreschi, Richard J Munthali, Juliana Kagura, Rihlat Said-Mohamed, Emanuella De Lucia Rolfe, Lisa K Micklesfield, Shane A Norris
BACKGROUND: The growing prevalence of overweight and obesity in low- or middle-income countries precipitates the need to examine early life predictors of adiposity. OBJECTIVES: To examine growth trajectories from birth, and associations with adult body composition in the Birth to Twenty Plus Cohort, Soweto, South Africa. METHODS: Complete data at year 22 was available for 1088 participants (536 males and 537 females). Conditional weight and height indices were generated indicative of relative rate of growth between years 0-2, 2-5, 5-8, 8-18, and 18-22...
2018: PloS One
https://www.readbyqxmd.com/read/29322322/functional-traits-can-improve-our-understanding-of-niche-and-dispersal-based-processes
#2
Feng Jiang, Yanhan Xun, Huiying Cai, Guangze Jin
Ecologists often determine the relative importance of niche- and dispersal-based processes via variation partitioning based on species composition. Functional traits and their proxies of phylogeny are expected to increase the detection of niche-based processes and reduce the unexplained variation relative to species identity. We collected eight adult tree traits and phylogenetic data of 41 species and employed a phylogenetic fuzzy weighting method to address this issue in a 9-ha temperate forest dynamics plot...
January 10, 2018: Oecologia
https://www.readbyqxmd.com/read/29318462/long-term-response-to-recombinant-human-growth-hormone-treatment-a-new-predictive-mathematical-method
#3
G Migliaretti, S Ditaranto, C Guiot, S Vannelli, P Matarazzo, N Cappello, I Stura, F Cavallo
INTRODUCTION: Recombinant GH has been offered to GH-deficient (GHD) subjects for more than 30 years, in order to improve height and growth velocity in children and to enhance metabolic effects in adults. AIM: The aim of our work is to describe the long-term effect of rhGH treatment in GHD pediatric patients, suggesting a growth prediction model. MATERIAL AND METHODS: A homogeneous database is defined for diagnosis and treatment modalities, based on GHD patients afferent to Hospital Regina Margherita in Turin (Italy)...
January 9, 2018: Journal of Endocrinological Investigation
https://www.readbyqxmd.com/read/29317533/the-social-genome-of-friends-and-schoolmates-in-the-national-longitudinal-study-of-adolescent-to-adult-health
#4
Benjamin W Domingue, Daniel W Belsky, Jason M Fletcher, Dalton Conley, Jason D Boardman, Kathleen Mullan Harris
Humans tend to form social relationships with others who resemble them. Whether this sorting of like with like arises from historical patterns of migration, meso-level social structures in modern society, or individual-level selection of similar peers remains unsettled. Recent research has evaluated the possibility that unobserved genotypes may play an important role in the creation of homophilous relationships. We extend this work by using data from 5,500 adolescents from the National Longitudinal Study of Adolescent to Adult Health (Add Health) to examine genetic similarities among pairs of friends...
January 9, 2018: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/29315403/joint-associations-of-a-polygenic-risk-score-and-environmental-risk-factors-for-breast-cancer-in-the-breast-cancer-association-consortium
#5
Anja Rudolph, Minsun Song, Mark N Brook, Roger L Milne, Nasim Mavaddat, Kyriaki Michailidou, Manjeet K Bolla, Qin Wang, Joe Dennis, Amber N Wilcox, John L Hopper, Melissa C Southey, Renske Keeman, Peter A Fasching, Matthias W Beckmann, Manuela Gago-Dominguez, Jose E Castelao, Pascal Guénel, Thérèse Truong, Stig E Bojesen, Henrik Flyger, Hermann Brenner, Volker Arndt, Hiltrud Brauch, Thomas Brüning, Arto Mannermaa, Veli-Matti Kosma, Diether Lambrechts, Machteld Keupers, Fergus J Couch, Celine Vachon, Graham G Giles, Robert J MacInnis, Jonine Figueroa, Louise Brinton, Kamila Czene, Judith S Brand, Marike Gabrielson, Keith Humphreys, Angela Cox, Simon S Cross, Alison M Dunning, Nick Orr, Anthony Swerdlow, Per Hall, Paul D P Pharoah, Marjanka K Schmidt, Douglas F Easton, Nilanjan Chatterjee, Jenny Chang-Claude, Montserrat García-Closas
Background: Polygenic risk scores (PRS) for breast cancer can be used to stratify the population into groups at substantially different levels of risk. Combining PRS and environmental risk factors will improve risk prediction; however, integrating PRS into risk prediction models requires evaluation of their joint association with known environmental risk factors. Methods: Analyses were based on data from 20 studies; datasets analysed ranged from 3453 to 23 104 invasive breast cancer cases and similar numbers of controls, depending on the analysed environmental risk factor...
January 5, 2018: International Journal of Epidemiology
https://www.readbyqxmd.com/read/29312590/gnrh-agonist-treatment-for-idiopathic-central-precocious-puberty-can-improve-final-adult-height-in-chinese-girls
#6
Yanqin Ying, Jing Tang, Wei Chen, Zemin Cai, Wan Ting Niu
Object: To study the outcomes of GnRHa on final adult height in Chinese idiopathic central precocious puberty (ICPP) girls and the involved factor(s) that can predict height gain. Methods: We conducted a retrospective analysis on 10 years of data obtained from three clinical hospitals from January 2005 to March 2015, and 101 girls with ICPP, who received GnRHa therapy for more than six months and already reached their adult height were enrolled. Results: Height, bone age, midparent height, HtSDS, sexual development, therapy duration and predicted adult height(PAH)at start and end of GnRHa, and the final adult height(FAH) were recorded and calculated...
December 12, 2017: Oncotarget
https://www.readbyqxmd.com/read/29310740/predicting-cardiometabolic-disturbances-from-waist-to-height-ratio-findings-from-the-brazilian-longitudinal-study-of-adult-health-elsa-brasil-baseline
#7
Marcelo Castanheira, Dóra Chor, José Uéleres Braga, Letícia de Oliveira Cardoso, Rosane Härter Griep, Maria Del Carmen Bisi Molina, Maria de Jesus Mendes da Fonseca
OBJECTIVE: To evaluate the performance of waist-to-height ratio (WHtR) in predicting cardiometabolic outcomes and compare cut-off points for Brazilian adults. DESIGN: Cross-sectional study. WHtR areas under the curve (AUC) were compared with those for BMI, waist circumference (WC) and waist-to-hip ratio (WHR). The outcomes of interest were hypertension, diabetes, hypertriacylglycerolaemia and presence of at least two components of metabolic syndrome (≥2 MetS)...
January 9, 2018: Public Health Nutrition
https://www.readbyqxmd.com/read/29301187/treatment-outcomes-of-gonadotropin-releasing-hormone-agonist-in-obese-girls-with-central-precocious-puberty
#8
Hye Ryun Kim, Hyo-Kyoung Nam, Young-Jun Rhie, Kee-Hyoung Lee
PURPOSE: This study investigated the influence of obesity on the clinical course and effect of gonadotropin-releasing hormone analog (GnRHa) treatment in girls with central precocious puberty (CPP). METHODS: Medical records of 182 girls with CPP treated with GnRHa were reviewed. They were divided into 2 groups: normal weight (n=108) and overweight/obesity (n=74). Chronological age (CA), bone age (BA), difference between BA and CA (BA-CA), standard deviation score (SDS) of height, body mass index (BMI), predicted adult height (PAH), and laboratory findings were compared at baseline, after 1 year, and at the end of GnRHa treatment in both groups...
December 2017: Annals of Pediatric Endocrinology & Metabolism
https://www.readbyqxmd.com/read/29282137/central-obesity-and-normal-weight-central-obesity-among-adults-attending-healthcare-facilities-in-buffalo-city-metropolitan-municipality-south-africa-a-cross-sectional-study
#9
Eyitayo Omolara Owolabi, Daniel Ter Goon, Oladele Vincent Adeniyi
BACKGROUND: Central obesity (CO) confers a significant threat on the cardio-metabolic health of individuals, independently of overall obesity. Disparities in the measures of fat distribution lead to misclassification of individuals who are at risk of cardio-metabolic diseases. This study sought to determine the prevalence and correlates of central obesity and normal-weight central obesity among adults attending selected healthcare facilities in Buffalo City Metropolitan Municipality (BCMM), South Africa, assess their health risk and examine the association between central obesity and cardio-metabolic diseases among adults with normal weight, measured by body mass index (BMI)...
December 28, 2017: Journal of Health, Population, and Nutrition
https://www.readbyqxmd.com/read/29280737/a-critical-appraisal-of-the-effect-of-gonadotropin-releasing-hormon-analog-treatment-on-adult-height-of-girls-with-central-precocious-puberty
#10
Abdullah Bereket
Central precocious puberty (CPP) is a diagnosis that pediatric endocrinologists worldwide increasingly make in girls of age 6-8 years and is mostly idiopathic. Part of the reason for increasing referral and diagnosis is the perception among the doctors as well as the patients that treatment of CPP with long-acting gonadotropin-releasing hormon analogues (GnRHa) promote height of the child. Although, the timing and the tempo of puberty does influence statural growth and achieved adult height, the extent of this effect is variable depending on several factors and is modest in most cases...
December 27, 2017: Journal of Clinical Research in Pediatric Endocrinology
https://www.readbyqxmd.com/read/29251181/assessment-of-geriatric-predictors-of-adherence-to-zoledronic-acid-treatment-for-osteoporosis-a-prospective-follow-up-study
#11
Ilker Tasci, Umit Cintosun, Umut Safer, M Ilkin Naharci, Ergun Bozoglu, Aydogan Aydogdu, Huseyin Doruk
Objectives Discontinuation of bisphosphonate treatment remains high even with the long acting parenteral options. Whether there are some unidentified causes of noncompliance more specific to aged individuals is unknown. The aim of this study was to investigate baseline predictors of adherence to Zoledronic acid (ZOL) infusions among non-demented older adults with osteoporosis. Methods Patients aged ≥ 65 years who received a first ever ZOL infusion for osteoporosis were prospectively enrolled. Risk factors for osteoporosis and fractures, comorbidities, geriatric assessment measures, including depression, and anticholinergic burden were determined at baseline...
December 18, 2017: Acta Clinica Belgica
https://www.readbyqxmd.com/read/29243156/comfort-eating-and-all-cause-mortality-in-the-us-health-and-retirement-study
#12
Jenna R Cummings, Ashley E Mason, Eli Puterman, A Janet Tomiyama
PURPOSE: Comfort eating is a prevalent behavior. Prior research shows that comfort eating is associated with reduced stress responses and increased metabolic risk across adolescence, young adulthood, and middle adulthood. The purpose of the current research was to test if comfort eating prospectively predicted all-cause mortality in older adulthood. METHOD: The US Health and Retirement Study is an ongoing, nationally representative, longitudinal study of older adults...
December 14, 2017: International Journal of Behavioral Medicine
https://www.readbyqxmd.com/read/29239783/early-adulthood-determinants-of-mid-life-leisure-time-physical-inactivity-stability-and-change-findings-from-a-prospective-birth-cohort
#13
Snehal M Pinto Pereira, Chris Power
OBJECTIVES: Physical inactivity is highly prevalent. Knowledge is needed of influences on inactive lifestyles. We aimed to establish whether early adult factors predict subsequent inactivity patterns in mid-adulthood. DESIGN: Leisure-time inactivity (activity frequency<1/week) was assessed at 33y and 50y in the 1958 British Birth cohort (N=12,271). METHODS: We assessed associations of early adult (23-33y) physical status, mental function, social, family and neighbourhood circumstances with four 33-50y patterns (never inactive, persistently inactive, deteriorating or improving) using multinomial logistic regression with and without adjustment for childhood factors (e...
November 22, 2017: Journal of Science and Medicine in Sport
https://www.readbyqxmd.com/read/29234195/simple-anthropometric-indices-are-useful-for-predicting-non-alcoholic-fatty-liver-disease-nafld-in-asian-indians
#14
Ayaskanta Singh, Sasmita Parida, Jimmy Narayan, Preetam Nath, Pradeep K Padhi, Girish K Pati, Prasanta K Parida, Chudamani Meher, Omprakash Agrawal, Shivaram P Singh
Background and aims: With the rising prevalence of obesity and metabolic syndrome, nonalcoholic fatty liver disease (NAFLD) has become the most common liver disorder in both developed and developing nations. Several studies on NAFLD have described waist circumference, a surrogate marker of visceral fat accumulation and waist height ratio as a better screening tool for NAFLD and metabolic syndrome than body mass index (BMI). We conducted this study to assess simple abdominal obesity indices as a predictor of NAFLD and determine the appropriate cut-off levels with reference to NAFLD...
December 2017: Journal of Clinical and Experimental Hepatology
https://www.readbyqxmd.com/read/29229080/association-of-adiposity-with-pulmonary-function-in-older-chinese-guangzhou-biobank-cohort-study
#15
Jing Pan, Lin Xu, Tai Hing Lam, Chao Qiang Jiang, Wei Sen Zhang, Ya Li Jin, Feng Zhu, Tong Zhu, G Neil Thomas, Kar Keung Cheng, Peymane Adab
OBJECTIVE: We examined the association between different adiposity indices and pulmonary function in Chinese adults in the Guangzhou Biobank Cohort Study (GBCS). METHODS: Participants with body mass index (BMI) < 18.5 (underweight) were excluded. Adiposity indices including BMI, waist circumference (WC), waist hip ratio, waist height ratio and body fat percentage were measured. Lung function was assessed by spirometry using a turbine flowmeter. We analyzed percent predicted for forced expiratory volume in 1 s (FEV1%), forced vital capacity (FVC %) and restrictive respiratory defect (FEV1/FVC ratio > low limits of normal and FVC % <0...
November 2017: Respiratory Medicine
https://www.readbyqxmd.com/read/29215803/reference-values-for-spirometry-derived-using-lambda-mu-sigma-lms-method-in-korean-adults-in-comparison-with-previous-references
#16
Bum Seak Jo, Jun Pyo Myong, Chin Kook Rhee, Hyoung Kyu Yoon, Jung Wan Koo, Hyoung Ryoul Kim
BACKGROUND: The present study aimed to update the prediction equations for spirometry and their lower limits of normal (LLN) by using the lambda, mu, sigma (LMS) method and to compare the outcomes with the values of previous spirometric reference equations. METHODS: Spirometric data of 10,249 healthy non-smokers (8,776 females) were extracted from the fourth and fifth versions of the Korea National Health and Nutrition Examination Survey (KNHANES IV, 2007-2009; V, 2010-2012)...
January 15, 2018: Journal of Korean Medical Science
https://www.readbyqxmd.com/read/29201320/does-the-low-density-lipoprotein-cholesterol-play-a-key-role-in-predicting-metabolic-syndrome-in-the-iranian-adult-population
#17
Karimollah Hajian-Tilaki, Behzad Heidari, Arefeh Hajian-Tilaki, Alireza Firouzjahi, Afsaneh Bakhtiari
Background: The low density lipoprotein cholestrol (LDL-C) has an important role in the pathogenesis of cardiovascular disease but its association and predictive accuracy with metabolic syndrome (MetS) remains controversial. The objective of this study was to investigate the association and predictive ability of LDL-C with MetS. Methods: We analyzed the data from a population-based cross-sectional study conducted on representative samples of an Iranian adult population...
2017: Caspian Journal of Internal Medicine
https://www.readbyqxmd.com/read/29197219/growth-response-to-growth-hormone-treatment-in-patients-with-shox-deficiency-can-be-predicted-by-the-cologne-prediction-model
#18
Heike Hoyer-Kuhn, Jeremy Franklin, Christine Jones, Werner F Blum, Eckhard Schoenau
Background Growth hormone (GH) treatment in children with short stature homeobox-containing gene (SHOX) deficiency is recognized to increase height velocity (HV) and adult height. Prediction of growth response continues to be a challenge. A comparatively accurate method is the Cologne prediction model developed in children with GH deficiency. The aim was to investigate whether this model also applies to patients with SHOX deficiency. Methods Included were 48 patients with SHOX deficiency confirmed by DNA analysis and treated with 0...
December 2, 2017: Journal of Pediatric Endocrinology & Metabolism: JPEM
https://www.readbyqxmd.com/read/29187061/accuracy-of-predictive-equations-for-energy-expenditure-in-mexicans-living-with-hiv-aids-with-and-without-antiretroviral-therapy
#19
Iván Armando Osuna-Padilla, Adriana Aguilar-Vargas, Andrea Villazón-De la Rosa, Yuria Ablanedo-Terrazas, Yetlanezi Vargas-Infante, Gustavo Reyes-Terán
INTRODUCTION: Determination of the resting energy expenditure (REE) is essential for planning nutrition therapy in patients with human immunodeficiency virus (HIV)/acquired immunodeficiency syndrome (AIDS) to help to improve their nutrition status. We aim to evaluate the agreement and accuracy of prediction equations that estimate the REE in a Mexican population with a diagnosis of HIV/AIDS with and without antiretroviral therapy (ART). METHODS: A cross-sectional study in Mexican patients with HIV/AIDS with and without ART...
February 1, 2017: JPEN. Journal of Parenteral and Enteral Nutrition
https://www.readbyqxmd.com/read/29183845/comparison-of-adiposity-indicators-associated-with-fasting-state-insulinemia-triglyceridemia-and-related-risk-biomarkers-in-a-nationally-representative-adult-population
#20
Henry S Kahn, Yiling J Cheng
AIMS: We hypothesized that height-corrected abdominal size (supine sagittal abdominal diameter/height ratio [SADHtR] or waist circumference/height ratio [WHtR]) would associate more strongly than body mass index (BMI, weight/height2) with levels of fasting insulin, triglycerides, and three derived biomarkers of insulin resistance. METHODS: Anthropometry, including SAD by caliper, was collected on 4398 adults in the 2011-2014 National Health and Nutrition Examination Survey...
November 25, 2017: Diabetes Research and Clinical Practice
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