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Cardiac radiation

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https://www.readbyqxmd.com/read/29780037/past-and-present-work-practices-of-european-interventional-cardiologists-in-the-context-of-radiation-protection-of-the-eye-lens-results-of-the-euraloc-study
#1
Joanna Karolina Domienik-Andrzejewska, Olivera Ciraj-Bjelac, Panagiotis Askounis, Peter Covens, Octavian Dragusin, Sophie Jacob, Jad Farah, Emilio Gianicolo, Renato Padovani, Pedro Manuel Peixoto Teles, Anders Widmark, Lara Struelens
This paper investigates over five decades of work practices in interventional cardiology with special emphasis on radiation protection. The analysis is based on the data from more than 400 cardiologists from different European countries recruited for EURALOC study collected in the period from 2014 to 2016. Information on the types of procedures performed and their annual mean number, fluoroscopy time, access site choice, X-ray units and radiation protection means used was collected using an occupational questionnaire...
May 21, 2018: Journal of Radiological Protection: Official Journal of the Society for Radiological Protection
https://www.readbyqxmd.com/read/29773446/effects-of-preparatory-coaching-and-home-practice-for-deep-inspiration-breath-hold-on-cardiac-dose-for-left-breast-radiation-therapy
#2
A Kim, A M Kalet, N Cao, D S Hippe, L C Fang, L Young, J Meyer, E V Lang, N A Mayr
AIMS: Deep inspiration breath hold (DIBH) reduces cardiac radiation exposure by creating cardiac-chest wall separation in breast cancer radiotherapy. DIBH requires sustaining chest wall expansion for up to 40 s and involves complex co-ordination of thoraco-abdominal muscles, which may not be intuitive to patients. We investigated the effect of in-advance preparatory DIBH coaching and home practice on cardiac doses. MATERIALS AND METHODS: Successive patients from 1 February 2015 to 31 December 2016 with left-sided breast cancer who underwent tangential field radiotherapy utilising the DIBH technique were included...
May 14, 2018: Clinical Oncology: a Journal of the Royal College of Radiologists
https://www.readbyqxmd.com/read/29769516/staying-safe-from-radiation-exposure-in-cath-lab-a-review
#3
K Pasha, H R Khan, A A Sumon
A successful cardiac catheterization Laboratory radiation safety program must manage patient and staff safety by reducing exposure to ionizing radiation to a level that is as low as reasonably achievable (ALARA). The first step in radiation safety is to avoid unnecessary use of ionizing radiation by justification of exposure, one of the basic principles of radiation protection. All individuals involved in fluoroscopic imaging procedures should familiarize themselves to the measures to protect themselves from exposure to unsafe doses of ionizing radiation...
April 2018: Mymensingh Medical Journal: MMJ
https://www.readbyqxmd.com/read/29769130/diagnostic-accuracy-of-low-dose-dual-source-cardiac-computed-tomography-as-compared-to-surgery-in-univentricular-heart-patients
#4
Narumol Chaosuwannakit, Pattarapong Makarawate
BACKGROUND: To evaluate the ability of low radiation dose dual-source computed tomography (DSCT) to depict the features of morphological univentricular heart and to define accuracy by comparing findings with surgery. METHODS: Low radiation dose dual-source cardiac computed tomography (CCT) of 33 cases of functional univentricular heart preliminary diagnosis by echocardiography compared with the results of surgery were retrospectively analyzed (aged 1 day to 4 years, median 5 months)...
May 16, 2018: Journal of Cardiothoracic Surgery
https://www.readbyqxmd.com/read/29764968/how-to-prevent-and-manage-radiation-induced-coronary-artery-disease
#5
REVIEW
Jason R Cuomo, Sean P Javaheri, Gyanendra K Sharma, Deepak Kapoor, Adam E Berman, Neal L Weintraub
Radiation-induced coronary heart disease (RICHD) is the second most common cause of morbidity and mortality in patients treated with radiotherapy for breast cancer, Hodgkin's lymphoma and other prevalent mediastinal malignancies. The risk of RICHD increases with radiation dose. Exposed patients may present decades after treatment with manifestations ranging from asymptomatic myocardial perfusion defects to ostial, triple-vessel disease and sudden cardiac death. RICHD is insidious, with a long latency and a tendency to remain silent late into the disease course...
May 15, 2018: Heart: Official Journal of the British Cardiac Society
https://www.readbyqxmd.com/read/29759775/real-time-x-mri-guided-left-ventricular-lead-implantation-for-targeted-delivery-of-cardiac-resynchronization-therapy
#6
Jonathan M Behar, Peter Mountney, Daniel Toth, Sabrina Reiml, Maria Panayiotou, Alexander Brost, Bernhard Fahn, Rashed Karim, Simon Claridge, Tom Jackson, Ben Sieniewicz, Nik Patel, Mark O'Neill, Reza Razavi, Kawal Rhode, Christopher Aldo Rinaldi
OBJECTIVES: This study sought to test the feasibility of a purpose-built, integrated software platform to process, analyze, and overlay cardiac magnetic resonance (CMR) data in real time within a combined cardiac catheter laboratory and magnetic resonance imaging scanner suite (X-MRI) to guide left ventricular (LV) lead implantation. BACKGROUND: Suboptimal LV lead position is a major determinant of poor cardiac resynchronization therapy (CRT) response, and the optimal site is highly patient specific...
August 2017: JACC. Clinical Electrophysiology
https://www.readbyqxmd.com/read/29744658/catheter-mri-and-ct-imaging-in-newborns-with-pulmonary-atresia-with-ventricular-septal-defect-and-aortopulmonary-collaterals-quantifying-the-risks-of-radiation-dose-and-anaesthetic-time
#7
David F A Lloyd, Sebastian Goreczny, Conal Austin, Tarique Hussain, Shakeel A Qureshi, Eric Rosenthal, Thomas Krasemann
A comprehensive understanding of the native pulmonary blood supply is crucial in newborns with pulmonary atresia with ventricular septal defect and aortopulmonary collaterals (PA/VSD/MAPCA). We sought to describe the accuracy in terms of identifying native pulmonary arteries, radiation dose and anaesthetic time associated with multi-modality imaging in these patients, prior to their first therapeutic intervention. Furthermore, we wanted to evaluate the cumulative radiations dose and anaesthetic time over the study period...
May 9, 2018: Pediatric Cardiology
https://www.readbyqxmd.com/read/29739328/a-novel-ultrafast-low-dose-computed-tomography-protocol-allows-concomitant-coronary-artery-evaluation-and-lung-cancer-screening
#8
Carlo Gaudio, Gennaro Petriello, Francesco Pelliccia, Alessandra Tanzilli, Alberto Bandiera, Gaetano Tanzilli, Francesco Barillà, Vincenzo Paravati, Massimo Pellegrini, Enrico Mangieri, Paolo Barillari
BACKGROUND: Cardiac computed tomography (CT) is often performed in patients who are at high risk for lung cancer in whom screening is currently recommended. We tested diagnostic ability and radiation exposure of a novel ultra-low-dose CT protocol that allows concomitant coronary artery evaluation and lung screening. METHODS: We studied 30 current or former heavy smoker subjects with suspected or known coronary artery disease who underwent CT assessment of both coronary arteries and thoracic area (Revolution CT, General Electric)...
May 8, 2018: BMC Cardiovascular Disorders
https://www.readbyqxmd.com/read/29736620/cardioprotective-effect-of-zingerone-against-oxidative-stress-inflammation-and-apoptosis-induced-by-cisplatin-or-gamma-radiation-in-rats
#9
Ahmed F Soliman, Lobna M Anees, Doaa M Ibrahim
Despite their clinical benefits in cancer treatment, the deleterious effects on heart following chemo/radiotherapy are of increasing importance. Zingerone, a natural polyphenol, possesses multiple biological activities, such as antioxidant and anti-inflammatory. Thus, the current study was designed to assess the potential cardioprotective effects of zingerone against cisplatin or γ-radiation. Zingerone was given by intragastric intubation (25 mg/kg) daily for three successive weeks prior to the induction of cardiotoxicity using a single dose of cisplatin (20 mg/kg, i...
May 7, 2018: Naunyn-Schmiedeberg's Archives of Pharmacology
https://www.readbyqxmd.com/read/29735190/potential-morbidity-reduction-with-proton-radiation-therapy-for-breast-cancer
#10
REVIEW
Lior Z Braunstein, Oren Cahlon
Proton radiotherapy confers significant dosimetric advantages in the treatment of malignancies that arise adjacent to critical radiosensitive structures. To date, these advantages have been most prominent in the treatment of pediatric and central nervous system malignancies, although emerging data support the use of protons among other anatomical sites in which radiotherapy plays an important role. With advances in the overall treatment paradigm for breast cancer, most patients with localized disease now exhibit long-term disease control and, consequently, may manifest the late toxicities of aggressive treatment...
April 2018: Seminars in Radiation Oncology
https://www.readbyqxmd.com/read/29735187/does-proton-therapy-offer-demonstrable-clinical-advantages-for-treating-thoracic-tumors
#11
REVIEW
Zhongxing Liao, Saumil J Gandhi, Steven H Lin, Jeffrey Bradley
The finite range of proton beams in tissues offers unique dosimetric advantages that theoretically allow dose to the target to be escalated while minimizing exposure of surrounding tissues and thus minimizing radiation-induced toxicity. This theoretical advantage has led to widespread adoption of proton therapy around the world for a wide variety of tumors at different anatomical sites. Many treatment-planning comparisons have shown that proton therapy has substantial dosimetric advantages over conventional radiotherapy...
April 2018: Seminars in Radiation Oncology
https://www.readbyqxmd.com/read/29724584/stereotactic-body-radiation-therapy-for-heart-base-tumors-in-six-dogs
#12
L M Magestro, T L Gieger, M W Nolan
INTRODUCTION: Heart-base tumors are increasingly treated with radiotherapy, yet safety and efficacy are incompletely understood. This case series describes outcomes after stereotactic body radiation therapy (SBRT) for presumed chemodectoma. ANIMALS: Six pet dogs. METHODS: A retrospective study was performed, including dogs with a clinical diagnosis of chemodectoma and treatment with three-fraction SBRT (30 Gy total). RESULTS: Heart-base tumors, presumed or confirmed to be chemodectomas, were diagnosed via histopathology or imaging...
April 30, 2018: Journal of Veterinary Cardiology: the Official Journal of the European Society of Veterinary Cardiology
https://www.readbyqxmd.com/read/29722650/locally-advanced-lung-cancer-is-it-time-to-take-cardiac-protection-seriously-in-radiation-planning
#13
James J Urbanic, Ronald C McGarry, Megan E Daly, David A Palma
No abstract text is available yet for this article.
April 1, 2018: International Journal of Radiation Oncology, Biology, Physics
https://www.readbyqxmd.com/read/29715111/chemotherapy-or-combined-modality-therapy-for-early-stage-hodgkin-lymphoma
#14
Jordan A Torok, Yuan Wu, Junzo Chino, Leonard R Prosnitz, Anne W Beaven, Grace J Kim, Chris R Kelsey
BACKGROUND/AIM: Optimizing treatment of early-stage Hodgkin lymphoma (HL) requires balancing cure with potential acute and late toxicities from treatment. We reviewed our institutional experience with chemotherapy alone (ChT) versus combined modality therapy (CMT). MATERIALS AND METHODS: Patients with stage I-II classical HL in a complete response (CR) by functional imaging after chemotherapy were included. Progression-free survival (PFS) and overall survival (OS) were calculated and a multivariate analysis (MVA) was performed...
May 2018: Anticancer Research
https://www.readbyqxmd.com/read/29713770/comprehensive-morphologic-and-functional-imaging-of-heart-transplant-patients-first-experience-with-dynamic-perfusion-ct
#15
S Oebel, S Hamada, K Higashigaito, J von Spiczak, E Klotz, F Enseleit, R Hinzpeter, F Ruschitzka, R Manka, H Alkadhi
OBJECTIVES: We aimed to assess the diagnostic performance of a combined protocol with coronary computed tomography angiography (CCTA) and stress CT perfusion imaging (CTP) in heart transplant patients for comprehensive morphological and functional imaging. METHODS: In this prospective study, 13 patients undergoing routine follow-up 8±6 years after heart transplantation underwent CCTA and dynamic adenosine stress CTP using a third-generation dual-source CT scanner, cardiac magnetic resonance (MR) adenosine stress perfusion imaging at 1...
April 30, 2018: European Radiology
https://www.readbyqxmd.com/read/29707295/percutaneous-occluder-device-closure-through-femoral-vein-guidance-by-transthoracic-echocardiography-in-adult-atrial-septal-defect-patients
#16
Yixin Jia, Xu Meng, Yan Li, Chunlei Xu, Wen Zeng, Yuqing Jiao, Wei Han
Background: This study aimed to summarize percutaneous occluder device closure of atrial septal defects (ASD) through the femoral vein, using guidance by transthoracic echocardiography under local anesthesia without radiation or fluoroscopic guidance. Methods: This was a case series of fourteen patients, 3 males and 11 females, diagnosed with central ASD, the diameter of the defect ranged from 9 to 32 mm, and the patients had no other heart malformations or organ dysfunction...
March 2018: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/29703501/heart-volume-reduction-during-radiotherapy-involving-the-thoracic-region-in-children-an-unexplained-phenomenon
#17
Irma W E M van Dijk, Jorrit Visser, Jan Wiersma, Jessica R van Boggelen, Brian V Balgobind, Elizabeth A M Lieke Feijen, Sophie C Huijskens, Wouter E M Kok, Leontien C M Kremer, Coen R N Rasch, Arjan Bel
BACKGROUND AND PURPOSE: Radiotherapy involving the thoracic region is associated with cardiotoxicity in long-term childhood cancer survivors. We quantified heart volume changes during radiotherapy in children (<18 years) and investigated correlations with patient and treatment related characteristics. MATERIAL AND METHODS: Between 2010 and 2016, 34 children received radiotherapy involving the thoracic region. We delineated heart contours and measured heart volumes on 114 CBCTs...
April 24, 2018: Radiotherapy and Oncology: Journal of the European Society for Therapeutic Radiology and Oncology
https://www.readbyqxmd.com/read/29703012/successful-treatment-of-left-main-shock-syndrome-induced-by-thrombosed-coronary-artery-dissection-a-case-report
#18
Xiaojun Bai, Weiping Zhang, Zuyi Yuan
RATIONALE: Left main shock syndrome (LMSS) induced by thrombosed coronary artery dissection is very rare and has a fatal prognosis. Optimal treatment strategy includes early reperfusion and hemodynamic support to prevent cardiogenic shock. However, it involves the extension of technical difficulties under different conditions. PATIENT CONCERNS: A 49-year-old woman developed symptoms of left main shock syndrome. The main clinical manifestations were retrosternal pain radiating to his back and left shoulder, heavy sweating, palpitation and brachypnea...
April 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29701608/quantitative-myocardial-perfusion-from-static-cardiac-and-dynamic-arterial-ct
#19
Michael Bindschadler, Kelley R Branch, Adam M Alessio
Quantitative myocardial blood flow (MBF) estimation by dynamic contrast enhanced cardiac computed tomography (CT) requires multi-frame acquisition of contrast transit through the blood pool and myocardium to inform the arterial input and tissue response functions. Both the input and the tissue response functions for the entire myocardium are sampled with each acquisition. However, the long breath holds and frequent sampling can result in significant motion artifacts and relatively high radiation dose. To address these limitations, we propose and evaluate a new static cardiac and dynamic arterial (SCDA) quantitative MBF approach where 1) the input function is well sampled using either prediction from pre-scan timing bolus data or measured from dynamic thin slice "bolus tracking" acquisitions, and 2) the whole-heart tissue response data is limited to one contrast enhanced CT acquisition...
April 27, 2018: Physics in Medicine and Biology
https://www.readbyqxmd.com/read/29699893/resource-requirements-and-reduction-in-cardiac-mortality-from-deep-inspiration-breath-hold-dibh-radiation-therapy-for-left-sided-breast-cancer-patients-a-prospective-service-development-analysis
#20
Sanjoy Chatterjee, Santam Chakraborty, Arunsingh Moses, Chandran Nallathambi, Anurupa Mahata, Samar Mandal, Rimpa Basu Achari, Indranil Mallick, Raj Kumar Shrimali, Tapesh Bhattacharyya, Sanjit Agrawal, Joydeep Ghosh, Rosina Ahmed
INTRODUCTION: Use of deep inspiration breath hold (DIBH) radiation therapy may reduce long-term cardiac mortality. The resource and time commitments associated with DIBH are impediments to its widespread adoption. We report the dosimetric benefits, workforce requirements, and potential reduction in cardiac mortality when DIBH is used for left-sided breast cancers. METHODS AND MATERIALS: Data regarding the time consumed for planning and treating 50 patients with left-sided breast cancer with DIBH and 20 patients treated with free breathing (FB) radiation therapy were compiled prospectively for all personnel (regarding person-hours [PH])...
March 21, 2018: Practical Radiation Oncology
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