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https://www.readbyqxmd.com/read/28430740/low-dose-computed-tomography-scans-with-automatic-exposure-control-for-patients-of-different-ages-undergoing-cardiac-pet-ct-and-spect-ct
#1
Ching-Ching Yang, Bang-Hung Yang, Chun-Yuan Tu, Tung-Hsin Wu, Shu-Hsin Liu
PURPOSE: This study aimed to evaluate the efficacy of automatic exposure control (AEC) in order to optimize low-dose computed tomography (CT) protocols for patients of different ages undergoing cardiac PET/CT and single-photon emission computed tomography/computed tomography (SPECT/CT). METHODS: One PET/CT and one SPECT/CT were used to acquire CT images for four anthropomorphic phantoms representative of 1-year-old, 5-year-old and 10-year-old children and an adult...
April 20, 2017: Nuclear Medicine Communications
https://www.readbyqxmd.com/read/28424841/dosimetric-predictors-of-radiation-induced-pericardial-effusion-in%C3%A2-esophageal-cancer
#2
Ichiro Ogino, Shigenobu Watanabe, Kentaro Sakamaki, Yuka Ogino, Chikara Kunisaki, Kazuo Kimura
PURPOSE: To evaluate the dose-volume parameters of the pericardium and heart in order to reduce the risk of radiation-induced pericardial effusion (PE) and symptomatic PE (SPE) in esophageal cancer patients treated with concurrent chemoradiotherapy. METHODS: In 86 of 303 esophageal cancer patients, follow-up CT was obtained at least 24 months after concurrent chemoradiotherapy. Correlations between clinical factors, including risk factors for cardiac disease, dosimetric factors, and the incidence of PE and SPE after radiotherapy were analyzed using Cox proportional hazard regression analysis...
April 19, 2017: Strahlentherapie und Onkologie: Organ der Deutschen Röntgengesellschaft ... [et Al]
https://www.readbyqxmd.com/read/28424445/management-of-tachyarrhythmia-during-pregnancy
#3
Emily Ann Enderlin, Khaldia Taufiq Khaled, Luke Oke, Mohammed Madmani, Hakan Paydak
Maternal tachyarrhythmia is a common complication during pregnancy due to hormonal changes that enhance pre-existing arrhythmias or induce new arrhythmias in the presence of congenital heart defects in pregnant females. Presence of tachyarrhythmia during pregnancy poses risk to the mother and fetus, calling for proper treatment with medications. Use of antiarrhythmic drugs in cases of maternal tachyarrhythmia must give due consideration of potential teratogenic side effects. Utilization of antiarrhythmic drugs during pregnancy has been well studied; some result in minimal fetal harm or none at all...
March 2017: Türk Kardiyoloji Derneği Arşivi: Türk Kardiyoloji Derneğinin Yayın Organıdır
https://www.readbyqxmd.com/read/28424090/targeted-endomyocardial-biopsy-guided-by-real-time-cardiovascular-magnetic-resonance
#4
Christina Unterberg-Buchwald, Christian Oliver Ritter, Verena Reupke, Robin Niklas Wilke, Christine Stadelmann, Michael Steinmetz, Andreas Schuster, Gerd Hasenfuß, Joachim Lotz, Martin Uecker
BACKGROUND: Endomyocardial biopsies (EMB) are an important diagnostic tool for myocarditis and other infiltrative cardiac diseases. Routinely, biopsies are obtained under fluoroscopic guidance with a substantial radiation burden. Despite procedural success, there is a large sampling error caused by missing the affected myocardium. Therefore, multiple (>6) biopsies are taken in the clinical setting. In cardiovascular magnetic resonance (CMR), late gadolinium enhancement (LGE) depicts areas of affected myocardium in myocarditis or in other infiltrative cardiomyopathies...
April 19, 2017: Journal of Cardiovascular Magnetic Resonance
https://www.readbyqxmd.com/read/28418949/initial-experience-with-simultaneous-18f-fdg-pet-mri-in-the-evaluation-of-cardiac-sarcoidosis-and-myocarditis
#5
Kate Hanneman, Michael Kadoch, Henry H Guo, Mehran Jamali, Andrew Quon, Andrei Iagaru, Robert Herfkens
PURPOSE: The purpose of this study was to compare combined PET/MRI with PET/CT and cardiac MRI in the evaluation of cardiac sarcoidosis and myocarditis. METHODS: Ten patients (4 men and 6 women; 56.1 ± 9.6 years old) were prospectively enrolled for evaluation of suspected cardiac sarcoidosis or myocarditis. Written informed consent was obtained. Following administration of 9.9 ± 0.9 mCi F-FDG, patients underwent standard cardiac PET/CT followed by combined PET/MRI using a simultaneous 3-T scanner...
April 17, 2017: Clinical Nuclear Medicine
https://www.readbyqxmd.com/read/28414936/east-urals-radioactive-trace-dose-dependent-functional-metabolic-effects-in-the-myocardium-of-the-pygmy-wood-mouse-apodemus-uralensis-taking-into-account-population-size
#6
Nataĺya A Orekhova, Makar V Modorov
The population dynamics, radiometric data and biochemical parameters (concentrations of total lipids, proteins, DNA and RNA, activity of succinate dehydrogenase, glucose phosphate isomerase and catalase, as well as lipid peroxidation level) in the myocardium of the pygmy wood mouse (Apodemus uralensis Pall., 1811) inhabiting the area of the East Urals Radioactive Trace (EURT) were analyzed. The functional-metabolic radiation effects as a result external and internal exposure to (137)Cs and (90)Sr (unweighted total dose rate 0...
April 14, 2017: Journal of Environmental Radioactivity
https://www.readbyqxmd.com/read/28414682/a-left-main-coronary-artery-thrombus-presenting-as-a-non-st-elevation-mi
#7
U Ezema, D Daberkow, T Delord, L Guidry, N R Sells
INTRODUCTION: Left main coronary artery (LMCA); thrombus with an acute myocardial infarction identified with coronary angiography is a clinically rare condition with an extremely high mortality rate. We present a case of LMCA thrombus that presented as a non-ST elevation myocardial infarction (NSTEMI);. CASE: A 45-year-old woman with a history of tobacco use and hyperlipidemia presented with a complaint of 10/10 "hard pain" across her chest radiating to her left shoulder and breast which woke her from sleep...
March 2017: Journal of the Louisiana State Medical Society: Official Organ of the Louisiana State Medical Society
https://www.readbyqxmd.com/read/28414679/misses-opportunity-tof-diagnoses-in-4th-decade-of-life
#8
O Baniahmad, T Jarreau, A Johnson
CASE: A 40 year old woman with a history of HIV, congestive heart failure secondary to an unknown congenital heart defect, and hypertension presented to our emergency department with worsening edema. On room air, oxygen saturation was 55 percent . On 5L of oxygen via nasal cannula, oxygen saturation was 88 percent . Physical examination was notable for central cyanosis, facial and lid edema, a II/VI holosystolic murmur across right chest radiating to entire right back hemithorax, decreased breath sounds at bases with pulmonary crackles, clubbing of fingers and edema of bilateral lower extremities...
March 2017: Journal of the Louisiana State Medical Society: Official Organ of the Louisiana State Medical Society
https://www.readbyqxmd.com/read/28412326/no-acute-changes-in-lvef-observed-with-concurrent-trastuzumab-and-breast-radiation-with-low-heart-doses
#9
Shelly X Bian, Mariam P Korah, Taylor R Whitaker, Lingyun Ji, Susan Groshen, Eugene Chung
INTRODUCTION/BACKGROUND: Treatment for HER2-postitive breast cancer often includes trastuzumab, breast/chest wall (CW) radiation (RT), and anthracyclines, all of which have cardiac toxicity. We aimed to evaluate the relationship between heart dose and acute left ventricular ejection fraction (LVEF) changes in patients who received concurrent trastuzumab and breast/CW RT with and without anthracycline use. PATIENTS AND METHODS: We retrospectively reviewed all nonmetastatic breast cancer patients from 2008 to 2015 who received concurrent trastuzumab and breast/CW RT...
March 23, 2017: Clinical Breast Cancer
https://www.readbyqxmd.com/read/28410102/scanned-three-dimensional-intracardiac-arfi-and-swei-for-imaging-radiofrequency-ablation-lesions
#10
Peter Hollender, Lily Kuo, Virginia Chen, Stephanie Eyerly, Patrick Wolf, Gregg Trahey
Radiofrequency ablation (RFA) is used to locally disrupt electrical propagation in myocardium and treat arrhythmias, and direct visualization of ablation lesions by acoustic radiation force methods may benefit RFA procedures. This work compares four imaging modalities, B-Mode, ARFI, STL-SWEI and MTL-SWEI, in their ability to resolve RFA lesions in four ex vivo experiments. Ablation lesions are shown to be marked by at least a local halving of ARFI displacements and doubling of shear wave speeds. In a controlled ablation of ex vivo porcine and canine cardiac tissue, STL-SWEI and ARFI are shown to have similar CNR, better than MTL-SWEI and B-Mode...
April 7, 2017: IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control
https://www.readbyqxmd.com/read/28408649/external-arrhythmia-ablation-using-photon-beams-ablation-of-the-atrioventricular-junction-in-an-intact-animal-model
#11
H Immo Lehmann, Amanda J Deisher, Mitsuru Takami, Jon J Kruse, Limin Song, Sarah E Anderson, Jack T Cusma, Kay D Parker, Susan B Johnson, Samuel J Asirvatham, Robert C Miller, Michael G Herman, Douglas L Packer
BACKGROUND: This study sought to investigate external photon beam radiation for catheter-free ablation of the atrioventricular junction in intact pigs. METHODS AND RESULTS: Ten pigs were randomized to either sham irradiation or irradiation of the atrioventricular junction (55, 50, 40, and 25 Gy). Animals underwent baseline electrophysiological evaluation, cardiac gated multi-row computed tomographic imaging for beam delivery planning, and intensity-modulated radiation therapy...
April 2017: Circulation. Arrhythmia and Electrophysiology
https://www.readbyqxmd.com/read/28401505/cardiac-applications-of-pet-mr
#12
REVIEW
Peter J Bergquist, Michael S Chung, Anja Jones, Mark A Ahlman, Charles S White, Jean Jeudy
PURPOSE OF REVIEW: The purpose of this study was to provide an overview of the clinical applications of PET-MR in the setting of cardiac imaging with emphasis on specific scenarios where both techniques together provided added information. RECENT FINDINGS: Synergy of cardiac PET and MR fusion may hold similar promise eliminating ionizing radiation and improving tissue contrast. Future development of new hybrid scanners, use of new imaging tracers, and clinical applications are significant factors which will influence its use...
May 2017: Current Cardiology Reports
https://www.readbyqxmd.com/read/28396082/pregnancy-related-spontaneous-coronary-artery-dissection-a%C3%A2-case-series-and-literature-review
#13
Emily Rose, Maheedhar Gedela, Nathan Miller, Paul L Carpenter
BACKGROUND: Cardiac emergencies during pregnancy are rare but have significant associated morbidity and mortality when they do occur. The emergency physician must not only be aware of potentially life-threatening conditions in the pregnant woman, but also know the emergent management and treatment of these conditions to avoid worsening of the underlying condition. Pregnancy-related spontaneous coronary artery dissection has been described in the cardiology literature, but is not well-known in emergency medicine literature...
April 7, 2017: Journal of Emergency Medicine
https://www.readbyqxmd.com/read/28395211/antioxidant-and-antiapoptotic-effects-of-sea-cucumber-and-valsartan-against-doxorubicin-induced-cardiotoxicity-in-rats-the-role-of-low-dose-gamma-irradiation
#14
Doaa M Ibrahim, Rasha R Radwan, Salma M Abdel Fattah
Doxorubicin (DOX) is a highly effective antineoplastic drug; however, the clinical use of DOX is limited by its dose dependent cardiotoxicity. This study was conducted to evaluate the cardioprotective effect of sea cucumber and valsartan against DOX-induced cardiotoxicity in rats. Also, the role of exposure to low dose γ radiation (LDR) on each of them was investigated, since LDR could suppress various reactive oxygen species-related diseases. Rats received DOX (2.5mg/kg, ip) in six equal injections over a period of 2weeks, sea cucumber (14...
March 31, 2017: Journal of Photochemistry and Photobiology. B, Biology
https://www.readbyqxmd.com/read/28393926/a-strategy-for-precise-treatment-of-cardiac-malignant-neoplasms
#15
Wenshuo Wang, Jinqiang Shen, Hongyue Tao, Yun Zhao, Hui Nian, Lai Wei, Xiaoyuan Ling, Ye Yang, Limin Xia
The prevalence of cardiac malignant neoplasms in the general population has been shown to be significant higher than what was previously estimated, yet their treatment has remained difficult and effective therapies are lacking. In the current study, we developed a novel thermotherapy in which PEG-functionalized carbon nanotubes were injected into the tumor regions to assist in the targeted delivery of infrared radiation energy with minimal hyperthermic damage to the surrounding normal tissues. In a mouse model of cardiac malignant neoplasms, the injected carbon nanotubes could rapidly induce coagulative necrosis of tumor tissues when exposed to infrared irradiation...
April 10, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28392465/l-carnitine-preserves-cardiac-function-by-activating-p38-mapk-nrf2-signalling-in-hearts-exposed-to-irradiation
#16
Zhigang Fan, Yang Han, Yuanpeng Ye, Chao Liu, Hui Cai
Radiation-induced heart damage (RIHD) is now considered to be one of the causes of mortality in cancer patients undergoing radiotherapy. Cardiac function impairments are clinical manifestations of RIHD. L-carnitine shows protective effects against irradiation and heart disease. This study was aimed to investigate the cardioprotective effects and potential molecular mechanisms of L-carnitine against RIHD. Mouse hearts were exposed to γ-radiation to induce RIHD. L-carnitine at doses of 100mg/Kg and 200mg/Kg was used to treat animals intraperitoneally...
April 6, 2017: European Journal of Pharmacology
https://www.readbyqxmd.com/read/28390673/diagnostic-performance-of-256-row-detector-coronary-ct-angiography-in-patients-with-high-heart-rates-within-a-single-cardiac-cycle-a%C3%A2-preliminary-study
#17
J Liang, H Wang, L Xu, L Yang, L Dong, Z Fan, R Wang, Z Sun
AIM: To evaluate the image quality and diagnostic performance of coronary computed tomography angiography (CCTA) in patients with high heart rate within a single cardiac cycle using a 256-row detector CT system. MATERIALS AND METHODS: Eighty-four consecutive symptomatic patients (mean age 60.4±9.1 years, 52 men) with suspected coronary artery disease and heart rate ≥75 beats/min undergoing CCTA and invasive coronary angiography (ICA) were enrolled retrospectively...
April 5, 2017: Clinical Radiology
https://www.readbyqxmd.com/read/28386043/nongated-cardiac-computed-tomographic-angiograms-for-detection-of-embolic-sources-in-acute-ischemic-stroke
#18
Leonard L L Yeo, Staffan Holmin, Tommy Andersson, Erik Lundström, Anil Gopinathan, Er Luen Lim, Benjamin S H Leong, Win Sen Kuan, Eric Ting, Benjamin Y Q Tan, Sterling Ellis Eide, Edgar L K Tay
BACKGROUND AND PURPOSE: We assessed the feasibility of obtaining diagnostic quality images of the heart and thoracic aorta by extending the z axis coverage of a non-ECG-gated computed tomographic angiogram performed in the primary evaluation of acute stroke without increasing the contrast dose. METHODS: Twenty consecutive patients with acute ischemic stroke within the 4.5 hours of symptom onset were prospectively recruited. We increased the longitudinal coverage to the domes of the diaphragm to include the heart...
April 6, 2017: Stroke; a Journal of Cerebral Circulation
https://www.readbyqxmd.com/read/28378112/automatic-determination-of-cardiovascular-risk-by-ct-attenuation-correction-maps-in-rb-82-pet-ct
#19
Ivana Išgum, Bob D de Vos, Jelmer M Wolterink, Damini Dey, Daniel S Berman, Mathieu Rubeaux, Tim Leiner, Piotr J Slomka
BACKGROUND: We investigated fully automatic coronary artery calcium (CAC) scoring and cardiovascular disease (CVD) risk categorization from CT attenuation correction (CTAC) acquired at rest and stress during cardiac PET/CT and compared it with manual annotations in CTAC and with dedicated calcium scoring CT (CSCT). METHODS AND RESULTS: We included 133 consecutive patients undergoing myocardial perfusion (82)Rb PET/CT with the acquisition of low-dose CTAC at rest and stress...
April 4, 2017: Journal of Nuclear Cardiology: Official Publication of the American Society of Nuclear Cardiology
https://www.readbyqxmd.com/read/28377296/mechanical-chest-compressions-improve-rate-of-return-of-spontaneous-circulation-and-allow-for-initiation-of-percutaneous-circulatory-support-during-cardiac-arrest-in-the-cardiac-catheterization-laboratory
#20
Joseph M Venturini, Elizabeth Retzer, J Raider Estrada, Janet Friant, David Beiser, Dana Edelson, Jonathan Paul, John Blair, Sandeep Nathan, Atman P Shah
BACKGROUND: Performing advanced cardiac life support (ACLS) in the cardiac catheterization laboratory (CCL) is challenging. Mechanical chest compression (MCC) devices deliver compressions in a small space, allowing for simultaneous percutaneous coronary intervention and reduced radiation exposure to rescuers. In refractory cases, MCC devices allow rescuers to initiate percutaneous mechanical circulatory support (MCS) and extracorporeal life support (ECLS) during resuscitation. This study sought to assess the efficacy and safety of MCC when compared to manual compressions in the CCL...
April 2, 2017: Resuscitation
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