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https://www.readbyqxmd.com/read/28715670/estimated-lifetime-effective-dose-to-hunters-and-their-families-in-the-three-most-contaminated-counties-in-sweden-after-the-chernobyl-nuclear-power-plant-accident-in-1986-a-pilot-study
#1
Martin Tondel, Christopher Rääf, Robert Wålinder, Afrah Mamour, Mats Isaksson
Hunters and their families were one of the most exposed subpopulations in Sweden after the Chernobyl nuclear power plant accident in 1986. In this pilot study we used existing registries and whole-body measurements to develop algorithms to calculate lifetime effective doses and collective doses to some hunters in Sweden. Ten hunters and their family members were randomly selected from each of the three most contaminated counties in Sweden (Västernorrland, Uppsala, Gävleborg) using the register for hunting weapons from the Police Authority in 1985...
July 14, 2017: Journal of Environmental Radioactivity
https://www.readbyqxmd.com/read/28715319/cad-based-virtual-humans-design-and-safety-assessment-of-mri-coils
#2
Gregory M Noetscher, Nicholas D Maino, Patrick Lacroix, Marc Horner, Sara Louie
Magnetic resonance imaging (MRI) is a ubiquitous tool used in clinical settings around the world to provide detailed three-dimensional information on the internal anatomy and physiology of human patients without the use of ionizing radiation, which is the primary safety concern associated with computed tomography. This information is obtained noninvasively and can be used in the diagnosis of pathological conditions as well as the monitoring of treatments.
July 2017: IEEE Pulse
https://www.readbyqxmd.com/read/28715316/virtual-humans-for-implantable-device-safety-assessment-in-mri-mitigating-magnetic-resonance-imaging-hazards-for-implanted-medical-devices
#3
James E Brown, Rui Qiang, Paul J Stadnik, Larry J Stotts, Jeffrey A Von Arx
Magnetic resonance imaging (MRI) is the preferred modality for soft tissue imaging because of its nonionizing radiation and lack of contrast agent. Due to interactions between the MR system and active implantable medical devices (AIMDs), patients with implants such as pacemakers are generally denied access to MRI, which presents a detriment to that population. It has been estimated that 50-75% of patients with a cardiac device were denied access to MRI scanning and, moreover, that 17% of pacemaker patients need an MRI within 12 months of implantation [1]...
July 2017: IEEE Pulse
https://www.readbyqxmd.com/read/28712889/the-adjustable-transobturator-male-system-in-stress-urinary-incontinence-after-transurethral-resection-of-the-prostate
#4
Alexander Friedl, Jenifer Schneeweiss, Kathrin Stangl, Sandra Mühlstädt, Roman Zachoval, Stephan Hruby, Therese Gründler, Danijel Kivaranovic, Paolo Fornara, Lukas Lusuardi, Clemens Brössner
Objective To investigate the efficacy and safety of the adjustable transobturator male system (ATOMS) in males with stress urinary incontinence (SUI) after transurethral resection of the prostate (TURP). Materials and methods From a large international prospectively administrated ATOMS-register we identified 49 patients with an ATOMS device due to persistent SUI after TURP. For evaluation males were divided into standard TURP (sTURP) and palliative/post radiation TURP (pTURP). Baseline and follow-up measurements included continence parameters, urodynamics, quality of life surveys (PGI-I, ICIQ-SF) and pain ratings...
July 13, 2017: Urology
https://www.readbyqxmd.com/read/28712283/stereotactic-radiotherapy-of-the-prostate-fractionation-and-utilization-in-the-united-states
#5
Joseph P Weiner, David Schwartz, Meng Shao, Virginia Osborn, Kwang Choi, David Schreiber
PURPOSE: To analyze the utilization and fractionation of extreme hypofractionation via stereotactic body radiotherapy (SBRT) in the treatment of prostate cancer. MATERIALS AND METHODS: Data was analyzed on men diagnosed with localized prostate cancer between 2004-2012 and treated with definitive-intent radiation therapy, as captured in the National Cancer Database. This database is a hospital-based registry that collects an estimated 70% of all diagnosed malignancies in the United States...
June 2017: Radiation Oncology Journal
https://www.readbyqxmd.com/read/28711160/-7-be-and-210-pb-wet-dry-deposition-in-melbourne-australia-and-the-development-of-deployable-units-for-radiological-emergency-monitoring
#6
Jane Courtier, Sandra Sdraulig, Gillian Hirth
A large stainless-steel collection tray (with a surface area of one square metre) was purpose built and mounted on the roof of the Australian Radiation Protection and Nuclear Safety Agency (ARPANSA) building at Yallambie, Victoria, Australia. Using this system two years' worth of wet/dry deposition samples have been collected and analysed. Smaller portable units were also developed for deployment in an emergency and/or for environmental monitoring. The cosmogenic radionuclide (7)Be and the naturally occurring terrestrial radionuclide (210)Pb have been used to validate the systems...
July 12, 2017: Journal of Environmental Radioactivity
https://www.readbyqxmd.com/read/28708043/reirradiation-spine-stereotactic-body-radiation-therapy-for-spinal-metastases-systematic-review
#7
Sten Myrehaug, Arjun Sahgal, Motohiro Hayashi, Marc Levivier, Lijun Ma, Roberto Martinez, Ian Paddick, Jean Régis, Samuel Ryu, Ben Slotman, Antonio De Salles
OBJECTIVE Spinal metastases that recur after conventional palliative radiotherapy have historically been difficult to manage due to concerns of spinal cord toxicity in the retreatment setting. Spine stereotactic body radiation therapy (SBRT), also known as stereotactic radiosurgery, is emerging as an effective and safe means of delivering ablative doses to these recurrent tumors. The authors performed a systematic review of the literature to determine the clinical efficacy and safety of spine SBRT specific to previously irradiated spinal metastases...
July 14, 2017: Journal of Neurosurgery. Spine
https://www.readbyqxmd.com/read/28707988/first-clinical-report-of-helical-tomotherapy-with-simultaneous-integrated-boost-for-synchronous-bilateral-breast-cancer
#8
Tabassum Wadasadawala, Shanu Jain, Siji Paul, Reena Phurailatpam, Kishore Joshi, Palak Popat, Sandip Tandon, Aruna Alahari, Rajiv Sarin
OBJECTIVE: Radiotherapy for synchronous bilateral breast cancer (SBBC) is technically very challenging. This study reports the clinical feasibility, dosimetry and safety of helical tomotherapy (HT) with simultaneous integrated boost (SIB) in patients treated with adjuvant radiotherapy for SBBC. MATERIAL AND METHODS: Twenty one women with SBBC treated with HT from January 2013 to June 2016 were retrospectively evaluated. Radiation lung toxicity was assessed using pulmonary function test (PFT) and high resolution computerized tomography scan (HRCT) scan at baseline and 1 year post RT in 18 patients...
July 14, 2017: British Journal of Radiology
https://www.readbyqxmd.com/read/28707955/use-of-fluoroscopy-and-potential-long-term-radiation-effects-on-cataract-formation
#9
Rutveej Patel, Justin Dubin, Ephrem Odoy Olweny, Sammy Elsamra, Robert E Weiss
INTRODUCTION: The lens of the eye is extremely susceptible to radiation and long-term exposure can induce cataract formation. Our objective was to explore the risk of cataract formation for urologists at our institution. METHODS: A retrospective review of a multi-surgeon database of fluoroscopic cases between 10/2013 to 12/2014 was queried. Procedures were performed by different subspecialties and ranged from stent insertion/ureteroscopy to percutaneous nephrolithotomy...
July 14, 2017: Journal of Endourology
https://www.readbyqxmd.com/read/28707144/efficacy-and-safety-of-argon-plasma-coagulation-in-the-management-of-extensive-chronic-radiation-proctitis-after-pelvic-radiotherapy-for-cervical-carcinoma
#10
Shyama Prem Sudha, D Kadambari
INTRODUCTION: Chronic radiation proctitis (CRP) usually develops 90 days or more after radiation. Currently, there is no standard available for the treatment of CRP. In argon plasma coagulation, monopolar diathermy is used to ionise the argon gas which coagulates the telengiectatic vessels in a noncontact fashion. However, there are very few studies which have reported its use in extensive CRP. We report the efficacy and safety of APC in seven patients with recurrent, extensive grade 3 radiation proctitis...
July 13, 2017: International Journal of Colorectal Disease
https://www.readbyqxmd.com/read/28706116/training-standards-in-neuroendovascular-surgery-program-accreditation-and-practitioner-certification
#11
REVIEW
Arthur L Day, Adnan H Siddiqui, Philip M Meyers, Tudor G Jovin, Colin P Derdeyn, Brian L Hoh, Howard Riina, Italo Linfante, Osama Zaidat, Aquilla Turk, Jay U Howington, J Mocco, Andrew J Ringer, Erol Veznedaroglu, Alexander A Khalessi, Elad I Levy, Henry Woo, Robert Harbaugh, Steven Giannotta
BACKGROUND AND PURPOSE: Neuroendovascular surgery is a medical subspecialty that uses minimally invasive catheter-based technology and radiological imaging to diagnose and treat diseases of the central nervous system, head, neck, spine, and their vasculature. To perform these procedures, the practitioner needs an extensive knowledge of the anatomy of the nervous system, vasculature, and pathological conditions that affect their physiology. A working knowledge of radiation biology and safety is essential...
July 13, 2017: Stroke; a Journal of Cerebral Circulation
https://www.readbyqxmd.com/read/28705916/biodistribution-and-dosimetry-of-18-f-meta-fluorobenzyl-guanidine-mfbg-a-first-in-human-pet-ct-imaging-study-of-patients-with-neuroendocrine-malignancies
#12
Neeta Pandit-Taskar, Pat B Zanzonico, Kevin D Staton, Jorge A Carrasquillo, Diane Reidy-Lagunes, Serge K Lyashchenko, Eva Burnazi, Hanwen Zhang, Jason S Lewis, Ronald Blasberg, Steven M Larson, Wolfgang Andreas Weber, Shakeel Modak
Introduction: Iodine-123-meta-iodobenzylguanidine ((123)I-MIBG) imaging is currently a mainstay in the evaluation of many neuroendocrine tumors, especially neuroblastoma. (123)I-MIBG imaging has several limitations that can be overcome by the use of a PET agent. (18)F-MFBG is a positron emission tomography (PET) analog of MIBG that may allow for single-day, high-resolution quantitative imaging. We conducted a first-in-human study of (18)F-MFBG PET imaging to evaluate the safety, feasibility, pharmacokinetics, and dosimetry of (18)F-MFBG in neuroendocrine tumors (NETs)...
July 13, 2017: Journal of Nuclear Medicine: Official Publication, Society of Nuclear Medicine
https://www.readbyqxmd.com/read/28701660/precision-in-wedge-off-axis-using-independent-dose-verification
#13
Hiroyuki Shimizu, Masanobu Itano, Takeshi Yamazaki, Ryo Takahashi, Tatsuya Kamima, Mikiko Yamashita, Hiromi Baba, Satoru Ishibashi, Yoshihiro Higuchi, Toshijiro Yamamoto, Yasuharu Sugawara, Aya Sato, Shiro Nishiyama, Satoshi Miyaoka, Daisuke Kawai, Hidenobu Tachibana
It is essential for quality assurance to verify the safety of each individual patient's plan in radiation therapy. The tolerance level for independent verification of monitor unit calculations for non-IMRT clinical radiotherapy has been shown in the AAPM TG114. Thus, we investigated the precision of independent MU (dose) verification considering a wedge off-axis calculation and we conducted a study at twelve institutes for independent verification with the wedge off-axis calculation. The results obtained with the wedge off-axis calculation showed better agreement with the treatment planning system calculation results than those without the former calculation in a phantom study and in the patient retrospective study...
2017: Japanese Journal of Medical Physics
https://www.readbyqxmd.com/read/28700357/are-three-weeks-hypofractionated-radiation-therapy-hfrt-comparable-to-six-weeks-for-newly-diagnosed-glioblastoma-patients-results-of-a-phase-ii-study
#14
Pierina Navarria, Federico Pessina, Stefano Tomatis, Riccardo Soffietti, Marco Grimaldi, Egesta Lopci, Arturo Chiti, Antonella Leonetti, Alessandra Casarotti, Marco Rossi, Luca Cozzi, Anna Maria Ascolese, Matteo Simonelli, Simona Marcheselli, Armando Santoro, Elena Clerici, Lorenzo Bello, Marta Scorsetti
BACKGROUND: The current standard of care for newly diagnosed glioblastoma (GBM) is surgical resection, followed by radiation therapy (RT) with concurrent and adjuvant temozolomide chemotherapy (TMZ-CHT).. The patients outcome is still poor. In this study we evaluated hypofractionated radiation therapy (HFRT), instead of standard fractionated radiation therapy, with concomitant and adjuvant TMZ chemotherapy, in terms of safety and effectiveness. METHODS: Patients with newly diagnosed GBM, Karnofsky performance scale (KPS) ≥70, and tumor up to 10 cm underwent maximal feasible surgical resection were treated...
June 28, 2017: Oncotarget
https://www.readbyqxmd.com/read/28699409/review-of-the-effectiveness-of-enteral-feeding-in-pediatric-oncology-patients
#15
Kaleena Trimpe, Michele R Shaw, Marian Wilson, Mel R Haberman
Enteral supplementation for nutritional support in pediatric oncology patients remains nonstandardized across institutions and between providers. Pediatric oncology patients frequently fail to meet their growth curve percentiles, lose weight, and/or are malnourished due to both the oncologic process as well as side effects from chemotherapy and radiation treatments. Methods of increasing weight include enteral feeding (nasogastric, nasoduodenal/jejunal, or gastrostomy), parenteral intravenous feeding, and oral supplementation...
July 1, 2017: Journal of Pediatric Oncology Nursing: Official Journal of the Association of Pediatric Oncology Nurses
https://www.readbyqxmd.com/read/28697913/uterine-transposition-technique-and-a-case-report
#16
Reitan Ribeiro, Juliano Camargo Rebolho, Fernanda Keiko Tsumanuma, Giovana Gugelmin Brandalize, Carlos Henrique Trippia, Karam Abou Saab
OBJECTIVE: To report the first uterine transposition for fertility preservation in a patient with rectal cancer. DESIGN: Case report. SETTING: Community hospital. PATIENT(S): A 26-year-old patient with stage cT3N1M0 rectal adenocarcinoma located 5 cm from the anal margin. INTERVENTION(S): Laparoscopic transposition of the uterus to the upper abdomen, outside of the scope of radiation, was performed to preserve fertility...
July 8, 2017: Fertility and Sterility
https://www.readbyqxmd.com/read/28696086/pregnancy-after-breast-cancer-hope-after-the-storm
#17
Valeria DE Simone, Olivia Pagani
INTRODUCTION: In the last decades, long-term outcomes of young women with breast cancer have greatly improved, raising several new survivorship needs which include fertility preservation and pregnancy. The prejudice against pregnancy after breast cancer is still alive among different healthcare providers (e.g. gynecologists, oncologists, general practitioners) and women are often confused and left alone in their family decision planning. EVIDENCE ACQUISITION AND SYNTHESIS: All the available retrospective data confirm pregnancy after breast cancer is safe both for the mother and the offspring, also in women with hormone receptor positive disease...
July 10, 2017: Minerva Ginecologica
https://www.readbyqxmd.com/read/28694170/safety-assessment-and-toxicological-profiling-of-a-novel-combinational-sunprotective-dermal-formulation-containing-melatonin-and-pumpkin-seed-oil
#18
Nilutpal Sharma Bora, Manash Pratim Pathak, Santa Mandal, Bhaskar Mazumder, Rudragoud Policegoudra, Pakalapati Srinivas Raju, Pronobesh Chattopadhyay
Ultraviolet (UV) radiation exposure has been known to cause irreparable damages to human skin. The daunting risk of UV radiation exposure faced by military personnel led to the development of a sunscreen formulation which has superior sun protection factor combined with the ability to counteract reactive oxygen species. The present work deals with the preclinical safety evaluation of the sunscreen formulation comprising of four US FDA approved UV filters; namely avobenzone, octinoxate, oxybenzone, titanium dioxide along with melatonin and pumpkin seed oil, via OECD protocols of assessing acute oral and dermal toxicity; skin sensitizing; skin irritating; ocular irritating and genotoxic potential...
July 8, 2017: Regulatory Toxicology and Pharmacology: RTP
https://www.readbyqxmd.com/read/28691525/diagnostic-performance-of-ct-guided-percutaneous-transthoracic-core-needle-biopsy-using-low-tube-voltage-100%C3%A2-kvp-comparison-with-conventional-tube-voltage-120%C3%A2-kvp
#19
Han Na Lee, Sang Min Lee, Jooae Choe, Sang Min Lee, Eun Jin Chae, Kyung-Hyun Do, Joon Beom Seo
Background Computed tomography (CT)-guided percutaneous transthoracic core needle biopsy (PTNB) is typically performed at 120 kVp tube voltage. However, there is no study that has demonstrated diagnostic performance including ground-glass nodules and radiation dose reduction at lower tube voltage in large population. Purpose To retrospectively compare the diagnostic performance and radiation dose between 100 kVp and 120 kVp during CT-guided PTNB. Material and Methods This study included 393 PTNBs performed in 385 patients (Group I; 120 kVp) from March 2011 to September 2011 and 1368 PTNBs performed in 1318 patients (Group II; 100 kVp) from October 2011 to December 2013...
January 1, 2017: Acta Radiologica
https://www.readbyqxmd.com/read/28688909/are-we-making-an-impact-with-incident-learning-systems-analysis-of-quality-improvement-interventions-using-total-body-irradiation-as-a-model-system
#20
Aileen Kim, Eric Ford, Matthew Spraker, Jing Zeng, Ralph Ermoian, Loucille Jordan, Gabrielle Kane, Matthew Nyflot
PURPOSE: Despite increasing interest in incident learning systems (ILS) to improve safety and quality in radiation oncology, little is known about interventions developed in response to safety data. We used total body irradiation (TBI) as a model system to study the effectiveness of interventions from our institutional ILS. METHODS AND MATERIALS: Near-miss event reports specific to TBI were identified from a departmental ILS from March 2012 to December 2015. The near-miss risk index was rated at multidisciplinary review from 0 (no potential harm) to 4 (critical potential harm)...
June 6, 2017: Practical Radiation Oncology
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