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3D surface scanning AND Breast

G Janani, Mamatha M Pillai, R Selvakumar, Amitava Bhattacharyya, C Sabarinath
The study of breast cancer metastasis is limited due to poor knowledge of molecular progression of breast tumor and varied heterogeneity. For a better understanding of tumor metastasis, a reliable 3D in vitro model bridging the gap between 2D cultures and in vivo animal model studies is essential. Our study is focused on two key points: (i) designing a 3D microenvironment for studying metastasis and (ii) simulating the metastasis milieu by inducing epithelial to mesenchymal transition (EMT) and mesenchymal to epithelial transition (MET)...
February 7, 2017: Biofabrication
Mathias Tremp, Pietro G di Summa, Dominique Schaakxs, Carlo M Oranges, Reto Wettstein, Daniel F Kalbermatten
BACKGROUND: Little is known about the influence of the underlying tissue as donor for nipple-areola complex (NAC) reconstruction. Also, there is a complete lack of knowledge about the fate of nipple volume. OBJECTIVES: The goal of this retrospective, single-institution study was to analyze a case series after nipple reconstruction using a multimodal evaluation including 3-dimensional (3D) laser scanner analyses. METHODS: Unilateral mastectomy patients after either expander-based or autologous breast reconstruction using the skate flap were included...
February 2017: Aesthetic Surgery Journal
Andrea L Merrill, Julliette Buckley, Rong Tang, Elena Brachtel, Upahvan Rai, James Michaelson, Amy Ly, Michelle C Specht, Yukako Yagi, Barbara L Smith
Lumpectomy with microscopically clear margins is a safe and effective approach for surgical management of breast carcinoma. Margins are positive for tumor in 18-50% of lumpectomies, as it is not possible to accurately determine the shape or microscopic borders of a tumor preoperatively or intraoperatively. We examined the 3D microanatomy and growth patterns of common breast carcinoma subtypes to provide guidance for lumpectomy surgery. Prospective consent was obtained for the use of excess tissue from patients undergoing lumpectomy or mastectomy for breast carcinoma...
January 2017: Breast Journal
Patrick Knott, Baron Lonner, Mark Smith, Erin Frommeyer, Yuan Ren
BACKGROUND: Clinicians who assess and treat patients for scoliosis typically use parameters that are all visible from the posterior view. Radiographs assess the internal spinal deformity, but do not directly evaluate body shape, either posterior or anterior. This is problematic, as the patient is most concerned about the way they appear in the mirror. An objective set of anterior measurements is needed to help quantify the anterior asymmetry that is present in scoliosis. METHODS: The design of this system of assessment was developed as a consensus of thinking from four points of view...
2016: Scoliosis and Spinal Disorders
Woo Yeon Lee, Min Jung Kim, Dae Hyun Lew, Seung Yong Song, Dong Won Lee
BACKGROUND: Accurate breast volume assessment is a prerequisite to preoperative planning, as well as intraoperative decision making in breast reconstruction surgery. The use of three-dimensional surface imaging (3D scanning) to assess breast volume has many advantages. However, before employing 3D scanning in the field, the tool's validity should be demonstrated. The purpose of this study was to confirm the validity of 3D-scanning technology for evaluating breast volume. METHODS: We reviewed the charts of 25 patients who underwent breast reconstruction surgery immediately after total mastectomy...
September 2016: Archives of Plastic Surgery
Danni Li, Audrey Cheong, Gregory P Reece, Melissa A Crosby, Michelle C Fingeret, Fatima A Merchant
Stereophotography is now finding a niche in clinical breast surgery, and several methods for quantitatively measuring breast morphology from 3D surface images have been developed. Breast ptosis (sagging of the breast), which refers to the extent by which the nipple is lower than the inframammary fold (the contour along which the inferior part of the breast attaches to the chest wall), is an important morphological parameter that is frequently used for assessing the outcome of breast surgery. This study presents a novel algorithm that utilizes three-dimensional (3D) features such as surface curvature and orientation for the assessment of breast ptosis from 3D scans of the female torso...
November 1, 2016: Computers in Biology and Medicine
Michael P Chae, Warren Matthew Rozen, Robert T Spychal, David J Hunter-Smith
BACKGROUND: Accurate volumetric analysis is an essential component of preoperative planning in both reconstructive and aesthetic breast procedures towards achieving symmetrization and patient-satisfactory outcome. Numerous comparative studies and reviews of individual techniques have been reported. However, a unifying review of all techniques comparing their accuracy, reliability, and practicality has been lacking. METHODS: A review of the published English literature dating from 1950 to 2015 using databases, such as PubMed, Medline, Web of Science, and EMBASE, was undertaken...
April 2016: Gland Surgery
C Lowanichkiattikul, M Dhanachai, C Sitathanee, S Khachonkham, P Khaothong
To determine the chest wall movement of each patient during deep inspiratory breath hold (DIBH) and expiratory breath hold (EBH) in postoperative breast cancer patients. Postoperative breast cancer patients who underwent CT simulation for 3D radiotherapy treatment planning during December 2012 to November 2013 were included. Before scanning the radio-opaque wire was placed on the surface for breast and chest wall visualization on CT images, then the patient underwent three phases of CT scanning (free breathing, DIBH, and EBH, respectively)...
2016: SpringerPlus
Michael Atlan, Maxence Bigerelle, Véronique Larreta-garde, Mathilde Hindié, Per Hedén
UNLABELLED: Several companies offer anatomically shaped breast implants but differences among manufacturers are often misunderstood. The shell texture is a crucial parameter for anatomically shaped implants to prevent rotation and to decrease the risk of capsular contracture, even though concerns have recently been raised concerning the complications associated with textured breast implants. The aim of this study was to characterize differences in terms of texture, cell adhesion, shape, and stiffness between some commonly used anatomically shaped implants from three different manufacturers...
February 2016: Aesthetic Plastic Surgery
Chong Huang, Yu Lin, Lian He, Daniel Irwin, Margaret M Szabunio, Guoqiang Yu
Noncontact diffuse correlation tomography (ncDCT) is an emerging technology for 3D imaging of deep tissue blood flow distribution without distorting hemodynamic properties. To adapt the ncDCT for imaging in vivo breast tumors, we designed a motorized ncDCT probe to scan over the breast surface. A computer-aided design (CAD)-based approach was proposed to create solid volume mesh from arbitrary breast surface obtained by a commercial 3D camera. The sources and detectors of ncDCT were aligned on the breast surface through ray tracing to mimic the ncDCT scanning with CAD software...
October 10, 2015: Applied Optics
Tao Sun, Wei Mong Tsang, Woo-Tae Park, Srinivas Merugu
Porous Si (PSi) used for microfabrication of a novel neural electrode was prepared on Si wafers by an anodization process. Surface morphology and porous structure of the PSi were characterized using scanning electron microscopy (SEM) and transmission electron microscopy (TEM). 3D inter-connected and nano sized pores were homogeneously formed across the surface. Wettability of the PSi was determined using a sessile drop method. Although Si-Hx functional groups on the PSi surface had negative effect on wettability, water contact angle of the PSi reduced to 34...
April 2015: Journal of Nanoscience and Nanotechnology
Zongyi Gong, Mark B Williams
PURPOSE: Breast specific gamma imaging or molecular breast imaging (BSGI) obtains 2D images of (99m)Tc sestamibi distribution in the breast. Molecular breast tomosynthesis (MBT) maps the tracer distribution in 3D by acquiring multiple projections over a limited angular range. Here, the authors compare the performance of the two technologies in terms of spatial resolution, lesion contrast, and contrast-to-noise ratio (CNR) in phantom studies under conditions of clinically relevant sestamibi dose and imaging time...
July 2015: Medical Physics
C Kalavagunta, G Lasio, B Yi, J Zhou, M Lin
PURPOSE: It is important to estimate dose to pacemaker (PM)/Implantable Cardioverter Defibrillator (ICD) before undertaking Accelerated Partial Breast Treatment using High Dose Rate (HDR) brachytherapy. Kim et al. have reported HDR PM/ICD dose using a single-source balloon applicator. To the authors knowledge, there have so far not been any published PM/ICD dosimetry literature for the Strut Adjusted Volume Implant (SAVI, Cianna Medical, Aliso Viejo, CA). This study aims to fill this gap by generating a dose look up table (LUT) to predict maximum dose to the PM/ICD in SAVI HDR brachytherapy...
June 2015: Medical Physics
M Lin, S Feigenberg
PURPOSE: To evaluate the effectiveness of using 3D-surface-image to guide breath-holding (BH) left-side breast treatment. METHODS: Two 3D surface image guided BH procedures were implemented and evaluated: normal-BH, taking BH at a comfortable level, and deep-inspiration-breath-holding (DIBH). A total of 20 patients (10 Normal-BH and 10 DIBH) were recruited. Patients received a BH evaluation using a commercialized 3D-surface- tracking-system (VisionRT, London, UK) to quantify the reproducibility of BH positions prior to CT scan...
June 2015: Medical Physics
Rebekah H Conley, Ingrid M Meszoely, Jared A Weis, Thomas S Pheiffer, Lori R Arlinghaus, Thomas E Yankeelov, Michael I Miga
PURPOSE: Unfortunately, the current re-excision rates for breast conserving surgeries due to positive margins average 20-40 %. The high re-excision rates arise from difficulty in localizing tumor boundaries intraoperatively and lack of real-time information on the presence of residual disease. The work presented here introduces the use of supine magnetic resonance (MR) images, digitization technology, and biomechanical models to investigate the capability of using an image guidance system to localize tumors intraoperatively...
December 2015: International Journal of Computer Assisted Radiology and Surgery
HyungJae Lee, Wooyoung Hong, Seunghyun Jeon, Yongdoo Choi, Youngnam Cho
An electroresponsive drug release system based on polypyrrole (Ppy) nanowires was developed to induce the local delivery of anticancer drug, doxorubicin (DOX), according to the applied electric field. DOX-conjugated Ppy nanowire (NW) (DOX/Ppy NW) array was initially prepared by electrochemical deposition of a mixture of pyrrole monomers and biotin as dopants in the anodic alumina oxide membrane as a sacrificial template. Morphological observation by scanning electron microscopy revealed free-standing and 3D nanotopographical features with large surface area and high density...
April 14, 2015: Langmuir: the ACS Journal of Surfaces and Colloids
Min Xu, Jianbin Li, Shanshan Liu, Suzhen Wang, Wei Wang, Fengxiang Li, Tonghai Liu, Jinming Yu
OBJECTIVE: To compare the methods of delineating the whole breast target volume based on surface marks, palpation and glandular tissue on CT images, and to explore the contouring criteria after breast-conserving surgery. METHODS: In 15 patients with breast cancer after breast-conserving surgery, the whole breast target was delineated in 3D CT simulation images each by three different methods. The target volume delineated according to anatomical marks were named CTVan, according to breast palpation named CTVpa, and according to glandular mammary tissue showing by CT images named CTVgl...
September 2014: Zhonghua Zhong Liu za Zhi [Chinese Journal of Oncology]
Mao Ye, Pravansu Mohanty, Gargi Ghosh
Recapitulating the native environment of bone tissue is essential to develop in vitro models of breast cancer bone metastasis. The bone is a composite material consisting of organic matrix and inorganic mineral phase, primarily hydroxyapatite. In this study, we report the mineralization of porous poly vinyl alcohol (PVA) scaffolds upon incubation in modified Hanks' Balanced Salt Solution (HBSS) for 14 days. Scanning electron microscopy, energy dispersive X-ray analysis, and X-ray diffraction analysis revealed that the deposited minerals have composition similar to hydroxyapatite...
November 2014: Materials Science & Engineering. C, Materials for Biological Applications
Yi Rong, Steve Walston, Meng Xu Welliver, Arnab Chakravarti, Allison M Quick
PURPOSE: To evaluate the use of 3D optical surface imaging as a surrogate for respiratory gated deep-inspiration breath-hold (DIBH) for left breast irradiation. MATERIAL AND METHODS: Patients with left-sided breast cancer treated with lumpectomy or mastectomy were selected as candidates for DIBH treatment for their external beam radiation therapy. Treatment plans were created on both free breathing (FB) and DIBH computed tomography (CT) simulation scans to determine dosimetric benefits from DIBH...
2014: PloS One
Kai Ji, Jie Luan, Chunjun Liu, Dali Mu, Lanhua Mu, Minqiang Xin, Jingjing Sun, Shilu Yin, Lin Chen
BACKGROUND: The dual-plane technique has been widely used in augmentation mammaplasty procedures. However, there are some concerns about aesthetic contour maintenance for long time after muscle releasing. This study aims to track and analyze breast dynamic morphological changes after dual-plane breast augmentation with three-dimensional (3D) scanning technique. METHODS: Thirteen dual-plane anatomic implant augmentation patients underwent 3D scanning preoperatively (pre-OP) and postoperatively in four time points (1 month: post-1M, 3 months: post-3M, 6 months: post-6M and 12 months: post-12M)...
2014: PloS One
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