keyword
https://read.qxmd.com/read/37969267/feasibility-of-chest-spiral-3d-ultrashort-echo-time-magnetic-resonance-imaging-for-intrathoracic-metastasis-work-up-in-breast-cancer
#21
JOURNAL ARTICLE
Kyung Jin Nam, Taewoo Kang, Ji Won Lee, Minhee Hwang, Jin You Kim, Jeong A Yeom, Yeon Joo Jeong
BACKGROUND: Chest computed tomography (CT) is routinely performed to evaluate intrathoracic metastasis in patients with breast cancer, but radiation exposure and its potential carcinogenic risks are major drawbacks. Furthermore, pulmonary imaging by magnetic resonance imaging (MRI) is limited by low proton density, rapid signal decay, and sensitivity to respiratory and cardiac motions in lung tissue. Recently, a respiratory gating spiral three-dimensional (3D) ultrashort echo time (UTE) volume interpolated breath-hold examination (VIBE) sequence for lung MRI provides high spatial-resolution images with reasonable scan times...
October 31, 2023: Journal of Thoracic Disease
https://read.qxmd.com/read/37905615/heart-and-coronary-artery-dose-sparing-in-left-sided-breast-cancer-3d-conformal-radiotherapy-vs-helical-tomotherapy
#22
JOURNAL ARTICLE
Isabella Palumbo, Marta Marcantonini, Michele Scialpi, Vittorio Bini, Maika DI Benedetto, Serena Nucciarelli, Christian Fulcheri, Elisabetta Perrucci, Cynthia Aristei
BACKGROUND/AIM: To compare heart, left ventricle (LV) and coronary artery dose-sparing with three-dimensional conformal radiotherapy (3D-CRT) vs. helical tomotherapy (HT) in left-sided breast cancer (BC). PATIENTS AND METHODS: 3D-CRT and HT treatments were planned for 20 patients (pts). Computed tomography (CT) scans without and with intravenous contrast (ic) were performed and co-registered. Left breast and organs at risk (OARs) were contoured. Dose-volume histograms (DVHs) for 3D-CRT and HT treatment plans were evaluated in terms of planning target volume for evaluation (PTVeval) coverage and dose to the OARs...
2023: In Vivo
https://read.qxmd.com/read/37866087/development-of-low-cost-and-personalized-external-silicone-breast-prosthesis-produced-by-additive-manufacturing-for-women-who-have-undergone-mastectomy-a-pilot-study
#23
JOURNAL ARTICLE
Juliane Cristina Leme, Rodrigo Martins de Oliveira Spinosa, Sandy Oliveira Leal, Anna Beatriz Barreto Hirsch, Angélica Lodovico, Roberta Targa Stramandinoli-Zanicotti, Maria Elizete Kunkel, Felipe Arruda Moura
BACKGROUND: The aim of this study was to develop a low-cost and personalized method for external breast prosthesis production. METHODS: The projected light method was used for the acquisition of the 3D geometry of the left breast of a healthy 29-year-old woman, 69 kg and 1.69 m. The 3D modeling software Blender was used to make the prosthesis model and mold with adjustments to the model's mesh, such as smoothing, assigning thickness, and creating the walls of the prosthesis mold...
October 13, 2023: Clinical Biomechanics
https://read.qxmd.com/read/37862767/preoperative-planning-using-virtual-reality-and-computed-tomography-angiogram-in-deep-inferior-epigastric-perforator-flap-breast-reconstruction
#24
JOURNAL ARTICLE
Anaïs Di Via Ioschpe, Borivoj Golijanin, David Benharush, Ariel Berl, Vladimir Perhulov, Dana Egozi
The gold standard for preoperative planning of deep inferior epigastric perforator (DIEP) flap breast reconstruction uses computed tomography angiography (CTA). Virtual reality (VR) circumnavigates the limitations of CTA by reconstructing a fully immersive and interactive 3D representation of the scan. Scans of 44 patients who underwent DIEP flap breast reconstruction were retrospectively reviewed and compared using CTA and VR imaging modalities. The objective of this research was to compare perforators found using VR to the ones identified using conventional CTA...
December 2023: Journal of Plastic, Reconstructive & Aesthetic Surgery: JPRAS
https://read.qxmd.com/read/37796341/stereoscopic-x-ray-image-and-thermo-optical-surface-guidance-for-breast-cancer-radiotherapy-in-deep-inspiration-breath-hold
#25
JOURNAL ARTICLE
Martin Buschmann, Daniela Kauer-Dorner, Stefan Konrad, Dietmar Georg, Joachim Widder, Barbara Knäusl
PURPOSE: To investigate the feasibility of a thermo-optical surface imaging (SGRT) system combined with room-based stereoscopic X‑ray image guidance (IGRT) in a dedicated breast deep inspiration breath-hold (DIBH) irradiation workflow. In this context, benchmarking of portal imaging (EPID) and cone-beam CT (CBCT) against stereoscopic X‑rays was performed. METHODS: SGRT + IGRT data of 30 left-sided DIBH breast patients (1 patient with bilateral cancer) treated in 351 fractions using thermo-optical surface imaging and X-ray IGRT were retrospectively analysed...
October 5, 2023: Strahlentherapie und Onkologie: Organ der Deutschen Röntgengesellschaft ... [et Al]
https://read.qxmd.com/read/37791264/imaging-and-quantification-of-the-tumor-microenvironment-of-triple-negative-breast-cancer-using-tpef-and-scanning-laser-optical-tomography
#26
JOURNAL ARTICLE
Hannes Kamin, Lena Nolte, Andreas Bleilevens, Elmar Stickeler, Dag Heinemann, Jochen Maurer, Sonja Johannsmeier, Tammo Ripken
Triple-negative breast cancer is an aggressive subtype of breast cancer that has a poor five-year survival rate. The tumor's extracellular matrix is a major compartment of its microenvironment and influences the proliferation, migration and the formation of metastases. The study of such dependencies requires methods to analyze the tumor matrix in its native form. In this work, the limits of SHG-microscopy, namely limited penetration depth, sample size and specificity, are addressed by correlative three-dimensional imaging...
September 1, 2023: Biomedical Optics Express
https://read.qxmd.com/read/37786066/optimal-fractionation-and-timing-of-weekly-cone-beam-ct-in-daily-surface-guided-radiotherapy-for-breast-cancer
#27
JOURNAL ARTICLE
H Peng, F Jin, H Yang, H Luo, L Tan
PURPOSE/OBJECTIVE(S): SGRT has been demonstrated as a promising supplement to CBCT in adjuvant breast cancer radiotherapy, but a rational combination mode is lacking in clinical practice. The aim of this study was to explore this mode and investigate its impact on setup and dose accuracy. MATERIALS/METHODS: Both daily SGRT and weekly CBCT images were acquired for 23 breast cancer patients receiving conventional fractionated radiotherapy after lumpectomy. Based on the scanning frequencies and time intervals of CBCT, sixteen modes were acquired by randomly selecting one (CBCT1 ), two (CBCTij ), three (CBCTijk ), four (CBCTijkl ), and five (CBCT12345 ) images from the patient's off-line CBCT images for fusion with SGRT...
October 1, 2023: International Journal of Radiation Oncology, Biology, Physics
https://read.qxmd.com/read/37786014/exploring-the-benefits-of-3d-printed-bolus-in-cone-beam-ct-for-modified-radical-mastectomy-breast-cancer
#28
JOURNAL ARTICLE
S T Li, Y H Chou, H J Huang, H C Chang, Y C Lee
PURPOSE/OBJECTIVE(S): To improve the accuracy of superficial dose coverage for patients undergoing modified radical mastectomy (MRM), boluses are frequently applied to the skin surface of targeted region during radiotherapy. The irregular curvature of MRM breast cases results in discrepancies of dosimetry and poor contact. Additionally, the presence of an air gap causes unnecessary high-dose escalation and uncertainty in dose calculation, making the use of commercial flat bolus problematic...
October 1, 2023: International Journal of Radiation Oncology, Biology, Physics
https://read.qxmd.com/read/37786005/enhancing-clinical-accuracy-in-dibh-pattern-detection-with-a-combined-ultrasonic-and-ir-sensor-system
#29
JOURNAL ARTICLE
J H Kwag, M Lindsey, T Hogan, B Hinton, W R Reed
PURPOSE/OBJECTIVE(S): This study aimed to develop a DIBH monitoring system using IR (Infrared- VL6180X Time of Flight) distance sensors and a microcontroller, and to demonstrate its functionality and performance in various irregular free and DIBH breathings from the left breast and lung patients. MATERIALS/METHODS: A total of ten patients who performed DIBH breathing for treatment planning and optimized treatment delivery were randomly selected for the study. The breathing motion of the system was tested using an RPM (Real-Time Positioning Management) phantom...
October 1, 2023: International Journal of Radiation Oncology, Biology, Physics
https://read.qxmd.com/read/37785910/evaluation-of-daily-patient-position-accuracy-and-calculation-of-setup-errors-with-skin-markers-and-surface-guided-radiotherapy-sgrt-in-breast-cancer
#30
JOURNAL ARTICLE
G Bakıcıerler, O Karakoyun Celik, B Sindir, Ö Duran Can, K Akgüngör
PURPOSE/OBJECTIVE(S): This study aims to compare the inter-fractional patient positioning errors between the use of skin markers and SGRT in patients receiving breast radiotherapy. It also includes calculating the inter- and intra-fractional PTV margins required for free breathing (FB) and deep inspiration breath-hold (DIBH) techniques due to setup uncertainties. MATERIALS/METHODS: The treatment data of a total of 2209 fractions from 80 patients who received whole breast or chest wall radiotherapy at an institution between March 2021 and December 2022 were retrospectively analyzed...
October 1, 2023: International Journal of Radiation Oncology, Biology, Physics
https://read.qxmd.com/read/37785247/virtual-reality-changes-the-concept-of-patients-education-patient-experience-report-study
#31
JOURNAL ARTICLE
A A Aldakheel, M Alwhaid, B S Julaidan, F A Alsamari, N M Alrajhi, M Aldehaim
PURPOSE/OBJECTIVE(S): Patients undergoing radiotherapy will undergo a tidy process of frequent imaging modalities in a specified position. Before each scan, they are brought to the education clinic to explain the procedure, patients' positioning and any further specific instructions for the patient to be done during the scan. This however might increase the anxiety level of the patients as well as not comprehending it fully where it might affect scan quality and/or prolong scan duration which will play an important rule on patients' experience and satisfaction...
October 1, 2023: International Journal of Radiation Oncology, Biology, Physics
https://read.qxmd.com/read/37784782/3d-surface-imaging-in-reducing-setup-error-for-prone-whole-breast-radiotherapy
#32
JOURNAL ARTICLE
T Cordero, P L Beagen, M E Daly, A M Monjazeb, X Zhao
PURPOSE/OBJECTIVE(S): For patients undergoing whole breast radiotherapy, treatment in the prone position allows for reduced dose to critical organs such as the heart and lungs. However, this treatment position comes with greater challenges in reproducibility and setup error given the unstable position. Our objective was to investigate the benefit of using 3D surface imaging to reduce daily setup errors for these patients. MATERIALS/METHODS: We performed a retrospective review of consecutive breast patients receiving prone breast radiotherapy at our institution...
October 1, 2023: International Journal of Radiation Oncology, Biology, Physics
https://read.qxmd.com/read/37784774/analysis-of-skin-dose-and-position-stability-for-a-new-personalized-device-for-breast-radiotherapy
#33
JOURNAL ARTICLE
T H Chen, S C Lin, J F Chiou, C P Chen, S M Hsu, K H Tseng, L S Lu
PURPOSE/OBJECTIVE(S): Whole breast irradiation is the standard treatment for patients with early-stage breast cancer. We previously developed a personalized breast support device (PERSBRA) that reduced heart and lung radiation exposure. However, the skin dose was concerned for the device due to its thickness. In this study, we designed the new honeycomb structures to reduce the dose to the skin and maintain stable breast position with this device. MATERIALS/METHODS: Three different structures of PERSBRA were designed...
October 1, 2023: International Journal of Radiation Oncology, Biology, Physics
https://read.qxmd.com/read/37784508/comparison-between-pre-pectoral-and-post-pectoral-implant-reconstruction-and-different-radiation-modalities-on-breast-reconstruction-complications
#34
JOURNAL ARTICLE
G E Naoum, A Niemierko, H Ababneh, M Ioakeim-Ioannidou, A G Taghian
PURPOSE/OBJECTIVE(S): Single Stage direct to implant (DTI) is a rising reconstruction approach. It has been speculated that prepectoral implant placement reduces reconstruction complications as well as using newer postmastectomy radiation (PMRT) modalities as protons. Largest series in this topic included 350 DTI patients with less than 30 patients receiving PMRT. MATERIALS/METHODS: We reviewed the charts of 2,187 patients (pts) who underwent mastectomy and reconstruction at our institution between 2000 and 2020...
October 1, 2023: International Journal of Radiation Oncology, Biology, Physics
https://read.qxmd.com/read/37784504/increased-complication-rates-with-proton-therapy-in-breast-cancer-patients-with-immediate-implant-based-reconstruction-single-institution-comparative-effectiveness-analysis
#35
JOURNAL ARTICLE
A G Taghian, G E Naoum, L Smith, M Ioakeim-Ioannidou, H Ababneh, S Macdonald, A Y Ho
PURPOSE/OBJECTIVE(S): To compare the impact of protons vs. photons on breast reconstruction complications, for patients (pts) receiving postmastectomy radiation (PMRT) with either single-stage direct-to-implant (DTI) or two-staged expander/implant (TE/I). MATERIALS/METHODS: We reviewed the charts of 578 pts who underwent immediate reconstruction followed by radiation at our institution between 2010 and 2020. Pts with implant-based reconstruction using either TE/I or DTI and PMRT delivery in the presence of the prosthesis were included...
October 1, 2023: International Journal of Radiation Oncology, Biology, Physics
https://read.qxmd.com/read/37684712/in-vivo-lymph-node-cest-dixon-mri-in-breast-cancer-patients-with-metastatic-lymph-node-involvement
#36
JOURNAL ARTICLE
Manus J Donahue, Paula M C Donahue, R Sky Jones, Maria Garza, Chelsea Lee, Niral J Patel, Andrea Cooper, Jill B De Vis, Ingrid Meszoely, Rachelle Crescenzi
PURPOSE: Axillary lymph nodes (LNs) often present a reservoir for metastatic breast cancer, yet metastatic LN involvement cannot be discerned definitively using diagnostic imaging. This study investigated whether in vivo CEST may discriminate LNs with versus without metastatic involvement. METHODS: 3T MRI was performed in patients with breast cancer before clinically-indicated mastectomy or lumpectomy with LN removal, after which LN metastasic involvement was determined using histological evaluation...
September 8, 2023: Magnetic Resonance in Medicine
https://read.qxmd.com/read/37658125/cost-effective-portable-patient-dedicated-three-dimensional-automated-breast-ultrasound-for-point-of-care-breast-cancer-screening
#37
JOURNAL ARTICLE
Claire Keun Sun Park, Tiana Trumpour, Amal Aziz, Jeffrey Scott Bax, David Tessier, Lori Gardi, Aaron Fenster
Breast cancer screening has substantially reduced mortality across screening populations. However, a clinical need persists for more accessible, cost-effective, and robust approaches for increased-risk and diverse patient populations, especially those with dense breasts where screening mammography is suboptimal. We developed and validated a cost-effective, portable, patient-dedicated three-dimensional (3D) automated breast ultrasound (ABUS) system for point-of-care breast cancer screening. The 3D ABUS system contains a wearable, rapid-prototype 3D-printed dam assembly, a compression assembly, and a computer-driven 3DUS scanner, adaptable to any commercially available US machine and transducer...
September 1, 2023: Scientific Reports
https://read.qxmd.com/read/37626840/breast-cancer-cell-type-and-biomechanical-properties-of-decellularized-mouse-organs-drives-tumor-cell-colonization
#38
JOURNAL ARTICLE
Anton D Pospelov, Olga M Kutova, Yuri M Efremov, Albina A Nekrasova, Daria B Trushina, Sofia D Gefter, Elena I Cherkasova, Lidia B Timofeeva, Peter S Timashev, Andrei V Zvyagin, Irina V Balalaeva
Tissue engineering has emerged as an indispensable tool for the reconstruction of organ-specific environments. Organ-derived extracellular matrices (ECM) and, especially, decellularized tissues (DCL) are recognized as the most successful biomaterials in regenerative medicine, as DCL preserves the most essential organ-specific ECM properties such as composition alongside biomechanics characterized by stiffness and porosity. Expansion of the DCL technology to cancer biology research, drug development, and nanomedicine is pending refinement of the existing DCL protocols whose reproducibility remains sub-optimal varying from organ to organ...
August 9, 2023: Cells
https://read.qxmd.com/read/37623512/evaluation-of-intraoperative-volumetric-assessment-of-breast-volume-using-3d-handheld-stereo-photogrammetric-device
#39
JOURNAL ARTICLE
Rafael Loucas, Marios Loucas, Sebastian Leitsch, Katarina Danuser, Gabriela Reichard, Omar Haroon, Julius Michael Mayer, Konstantin Koban, Thomas Holzbach
Methods for assessing three-dimensional (3D) breast volume are becoming increasingly popular in breast surgery. However, the precision of intraoperative volumetric assessment is still unclear. Until now, only non-validated scanning systems have been used for intraoperative volumetric analyses. This study aimed to assess the feasibility, handling, and accuracy of a commercially available, validated, and portable device for intraoperative 3D volumetric evaluation. All patients who underwent breast surgery from 2020 to 2022 were identified from our institutional database...
August 15, 2023: Journal of Personalized Medicine
https://read.qxmd.com/read/37543211/the-use-of-anatomage-table-for-metastases-to-the-oral-region
#40
JOURNAL ARTICLE
Paolo Boffano, Francesca Boccafoschi, Matteo Brucoli, Vincenzo Rocchetti
INTRODUCTION: The Anatomage Table is a modern device characterized by virtual reality functionality that may be used to enhance the teaching of human anatomy to medical and allied health students. The purpose of the present study was to use the virtual dissection table (3D Anatomage) as an additional tool for education and information in cases of metastases to the oral region. MATERIALS AND METHODS: The hospital database of Vercelli Hospital, Vercelli, Italy, was searched for metastases to the oral region...
August 3, 2023: Journal of Stomatology, Oral and Maxillofacial Surgery
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