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https://www.readbyqxmd.com/read/28585511/three-dimensional-ultrasound-elasticity-imaging-on-an-automated-breast-volume-scanning-system
#1
Yuqi Wang, Haidy G Nasief, Sarah Kohn, Andy Milkowski, Tom Clary, Stephen Barnes, Paul E Barbone, Timothy J Hall
Ultrasound elasticity imaging has demonstrated utility in breast imaging, but it is typically performed with handheld transducers and two-dimensional imaging. Two-dimensional (2D) elastography images tissue stiffness of only a plane and hence suffers from errors due to out-of-plane motion, whereas three-dimensional (3D) data acquisition and motion tracking can be used to track out-of-plane motion that is lost in 2D elastography systems. A commercially available automated breast volume scanning system that acquires 3D ultrasound data with precisely controlled elevational movement of the 1D array ultrasound transducer was employed in this study...
June 1, 2017: Ultrasonic Imaging
https://www.readbyqxmd.com/read/28550674/-a-comparison-of-dosimetric-variance-for-external-beam-partial-breast-irradiation-using-three-dimensional-and-four-dimensional-computed-tomography
#2
B Guo, J B Li, W Wang, M Xu, Q Shao, T H Liu
Objective: To investigate the potential dosimetric benefits of four-dimensional computed tomography (4DCT) compared to three-dimensional CT (3DCT) in the planning of radiotherapy for external-beam partial breast irradiation (EB-PBI). Methods: Three-DCT and 4DCT scan sets were acquired for 20 patients who underwent EB-PBI. For each patient a conventional 3D conformal plan (3D-CRT) was generated based on end-inhalation phase (EI). The treatment plan based on the 4DCT EI phase images was copied and applied to the end-exhalation phase (EE) and 3DCT images (defined as EB-PBI(EI), EB-PBI(EE), EB-PBI(3D), respectively)...
April 23, 2017: Zhonghua Zhong Liu za Zhi [Chinese Journal of Oncology]
https://www.readbyqxmd.com/read/28526893/do-we-need-3d-tube-current-modulation-information-for-accurate-organ-dosimetry-in-chest-ct-protocols-dose-comparisons
#3
Xochitl Lopez-Rendon, Guozhi Zhang, Walter Coudyzer, Wim Develter, Hilde Bosmans, Federica Zanca
OBJECTIVES: To compare the lung and breast dose associated with three chest protocols: standard, organ-based tube current modulation (OBTCM) and fast-speed scanning; and to estimate the error associated with organ dose when modelling the longitudinal (z-) TCM versus the 3D-TCM in Monte Carlo simulations (MC) for these three protocols. METHOD: Five adult and three paediatric cadavers with different BMI were scanned. The CTDIvol of the OBTCM and the fast-speed protocols were matched to the patient-specific CTDIvol of the standard protocol...
May 19, 2017: European Radiology
https://www.readbyqxmd.com/read/28472167/3d-forest-an-application-for-descriptions-of-three-dimensional-forest-structures-using-terrestrial-lidar
#4
Jan Trochta, Martin Krůček, Tomáš Vrška, Kamil Král
Terrestrial laser scanning is a powerful technology for capturing the three-dimensional structure of forests with a high level of detail and accuracy. Over the last decade, many algorithms have been developed to extract various tree parameters from terrestrial laser scanning data. Here we present 3D Forest, an open-source non-platform-specific software application with an easy-to-use graphical user interface with the compilation of algorithms focused on the forest environment and extraction of tree parameters...
2017: PloS One
https://www.readbyqxmd.com/read/28463932/compressed-sensing-for-breast-mri-resolving-the-trade-off-between-spatial-and-temporal-resolution
#5
Suzan Vreemann, Alejandro Rodriguez-Ruiz, Dominik Nickel, Laura Heacock, Linda Appelman, Jan van Zelst, Nico Karssemeijer, Elisabeth Weiland, Marnix Maas, Linda Moy, Berthold Kiefer, Ritse M Mann
OBJECTIVE: Ultrafast dynamic contrast-enhanced magnetic resonance imaging of the breast enables assessment of the contrast inflow dynamics while providing images with diagnostic spatial resolution. However, the slice thickness of common ultrafast techniques still prevents multiplanar reconstruction. In addition, some temporal blurring of the enhancement characteristics occurs in case view-sharing is used. We evaluate a prototype compressed-sensing volume-interpolated breath-hold examination (CS-VIBE) sequence for ultrafast breast MRI that improves through plane spatial resolution and avoids temporal blurring while maintaining an ultrafast temporal resolution (less than 5 seconds per volume)...
May 1, 2017: Investigative Radiology
https://www.readbyqxmd.com/read/28398929/comprehensive-dynamic-contrast-enhanced-3d-magnetic-resonance-imaging-of-the-breast-with-fat-water-separation-and-high-spatiotemporal-resolution-using-radial-sampling-compressed-sensing-and-parallel-imaging
#6
Thomas Benkert, Kai Tobias Block, Samantha Heller, Melanie Moccaldi, Daniel K Sodickson, Sungheon Gene Kim, Linda Moy
OBJECTIVES: The aim of this study was to assess the applicability of Dixon radial volumetric encoding (Dixon-RAVE) for comprehensive dynamic contrast-enhanced 3D magnetic resonance imaging (MRI) of the breast using a combination of radial sampling, model-based fat/water separation, compressed sensing, and parallel imaging. MATERIALS AND METHODS: In this Health Insurance Portability and Accountability Act-compliant prospective study, 24 consecutive patients underwent bilateral breast MRI, including both conventional fat-suppressed and non-fat-suppressed precontrast T1-weighted volumetric interpolated breath-hold examination (VIBE)...
April 11, 2017: Investigative Radiology
https://www.readbyqxmd.com/read/28380921/high-efficiency-fabrication-of-complex-microtube-arrays-by-scanning-focused-femtosecond-laser-bessel-beam-for-trapping-releasing-biological-cells
#7
Liang Yang, Shengyun Ji, Kenan Xie, Wenqiang Du, Bingjie Liu, Yanlei Hu, Jiawen Li, Gang Zhao, Dong Wu, Wenhao Huang, Suling Liu, Hongyuan Jiang, Jiaru Chu
In this paper, we present a focused femtosecond laser Bessel beam scanning technique for the rapid fabrication of large-area 3D complex microtube arrays. The femtosecond laser beam is converted into several Bessel beams by two-dimensional phase modulation using a spatial light modulator. By scanning the focused Bessel beam along a designed route, microtubes with variable size and flexible geometry are rapidly fabricated by two-photon polymerization. The fabrication time is reduced by two orders of magnitude in comparison with conventional point-to-point scanning...
April 3, 2017: Optics Express
https://www.readbyqxmd.com/read/28362737/depth-encoded-optical-coherence-elastography-for-simultaneous-volumetric-imaging-of-two-tissue-faces
#8
Qi Fang, Luke Frewer, Philip Wijesinghe, Wes M Allen, Lixin Chin, Juliana Hamzah, David D Sampson, Andrea Curatolo, Brendan F Kennedy
Depth-encoded optical coherence elastography (OCE) enables simultaneous acquisition of two three-dimensional (3D) elastograms from opposite sides of a sample. By the choice of suitable path-length differences in each of two interferometers, the detected carrier frequencies are separated, allowing depth-ranging from each interferometer to be performed simultaneously using a single spectrometer. We demonstrate depth-encoded OCE on a silicone phantom and a freshly excised sample of mouse liver. This technique minimizes the required spectral detection hardware and halves the total scan time...
April 1, 2017: Optics Letters
https://www.readbyqxmd.com/read/28342616/performance-of-leading-artifact-removal-algorithms-assessed-across-microwave-breast-imaging-prototype-scan-configurations
#9
M A Elahi, C Curtis, B R Lavoie, M Glavin, E Jones, E Fear, M O'Halloran
Microwave imaging is a promising imaging modality for the detection of early-stage breast cancer. One of the most important signal processing components of microwave radar-based breast imaging is early-stage artifact removal. Several artifact removal algorithms have been reported in the literature. However, the neighbourhood-based skin subtraction and hybrid artifact removal algorithms have shown particularly promising results in different realistic 3D breast phantoms. For the first time in this paper, both algorithms have been evaluated and compared using the scan approaches of the most common microwave breast imaging prototype systems...
March 2, 2017: Computerized Medical Imaging and Graphics: the Official Journal of the Computerized Medical Imaging Society
https://www.readbyqxmd.com/read/28273058/magnetic-resonance-imaging-versus-3-dimensional-laser-scanning-for-breast-volume-assessment-after-breast-reconstruction
#10
Benjamin H L Howes, David I Watson, Beverley Fosh, Jia Miin Yip, Pakan Kleinig, Nicola Ruth Dean
BACKGROUND: There are several methods available for measuring breast volume in the clinical setting, but the comparability and accuracy of different methods is not well described. The ideal breast volume measurement technique should be low cost, comfortable for the patient, have no ionizing radiation and be non-invasive. METHODS: Prospective cohort study comparing a 3-dimensional (3D) laser scanner versus noncontrast magnetic resonance imaging (MRI) for breast volume assessment...
April 2017: Annals of Plastic Surgery
https://www.readbyqxmd.com/read/28211058/a-feasibility-study-of-a-hybrid-breast-immobilization-system-for-early-breast-cancer-in-proton-beam-therapy
#11
Takeshi Arimura, Takashi Ogino, Takashi Yoshiura, Mitsugi Matsuyama, Naoaki Kondo, Hideki Miyazaki, Akari Sakuragi, Takayuki Ohara, Etsuyo Ogo, Yoshio Hishikawa
PURPOSE: We aimed to develop a new breast-immobilizing system for proton beam therapy (PBT) of early breast cancer (EBC) that would provide the optimum breast shape during the treatment as well as increased fixation reliability by reducing the influence of respiratory movement. METHODS: The breast-immobilizing system (HyBIS; hybrid breast-immobilizing system) consists of a whole body immobilization system (WBIS), position-converting device (to change patient position), photo-scanning system, breast cup (made using a three-dimensional printer), breast cup-fitting apparatus, breast cup-holding device (to ensure the breast remains lifted in the supine position), and dedicated stretcher fixed to the WBIS (to carry the patient)...
April 2017: Medical Physics
https://www.readbyqxmd.com/read/28206760/nanoengineered-eggshell-silver-tailored-copolyester-polymer-blend-film-with-antimicrobial-properties
#12
Boniface J Tiimob, Gregory Mwinyelle, Woubit Abdela, Temesgen Samuel, Shaik Jeelani, Vijaya K Rangari
In this study, the reinforcement effect of different proportions of eggshell/silver (ES-Ag) nanomaterial on the structural and antimicrobial properties of 70/30 poly(butylene-co-adipate terephthalate)/polylactic acid (PBAT/PLA) immiscible blends was investigated. The ES-Ag was synthesized using a single step ball milling process and characterized with X-ray diffraction (XRD), X-ray photoelectron spectroscopy (XPS), and transmission electron microscopy (TEM). These results confirmed the existence of silver nanoparticles (Ag NPs) in the interstitial spaces of the eggshell particles...
March 8, 2017: Journal of Agricultural and Food Chemistry
https://www.readbyqxmd.com/read/28174297/decorin-inducible-peg3-evokes-beclin-1-mediated-autophagy-and-thrombospondin-1-mediated-angiostasis
#13
Annabel Torres, Maria A Gubbiotti, Renato V Iozzo
We previously discovered that systemic delivery of decorin for treatment of breast carcinoma xenografts induces paternally expressed gene 3 (Peg3), an imprinted gene encoding a zinc finger transcription factor postulated to function as a tumor suppressor. Here we found that de novo expression of Peg3 increased Beclin 1 promoter activity and protein expression. This process required the full-length Peg3 as truncated mutants lacking either the N-terminal SCAN domain or the zinc fingers failed to translocate to the nucleus and promote Beclin 1 transcription...
March 24, 2017: Journal of Biological Chemistry
https://www.readbyqxmd.com/read/28166261/radiomic-analysis-reveals-dce-mri-features-for-prediction-of-molecular-subtypes-of-breast-cancer
#14
Ming Fan, Hui Li, Shijian Wang, Bin Zheng, Juan Zhang, Lihua Li
The purpose of this study was to investigate the role of features derived from breast dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) and to incorporated clinical information to predict the molecular subtypes of breast cancer. In particular, 60 breast cancers with the following four molecular subtypes were analyzed: luminal A, luminal B, human epidermal growth factor receptor-2 (HER2)-over-expressing and basal-like. The breast region was segmented and the suspicious tumor was depicted on sequentially scanned MR images from each case...
2017: PloS One
https://www.readbyqxmd.com/read/28107436/a-micro-ct-study-in-patients-with-breast-microcalcifications-using-a-mathematical-algorithm-to-assess-3d-structure
#15
David Kenkel, Zsuzsanna Varga, Heike Heuer, Konstantin J Dedes, Nicole Berger, Lukas Filli, Andreas Boss
PURPOSE: The aim of this study was to evaluate the relevance of the three-dimensional (3D) structure of breast microcalcifications (MC) as a predictor of malignancy using highly resolved micro-computed tomography (micro-CT) datasets of biopsy samples. MATERIAL AND METHODS: The study included 28 women with suspicious MC in their mammogram undergoing vacuum-assisted biopsy. Directly after the intervention, the specimens were scanned in a micro-CT with an isometric spatial resolution of 9 μm...
2017: PloS One
https://www.readbyqxmd.com/read/28074018/evaluation-of-dose-homogeneity-in-cone-beam-breast-computed-tomography
#16
Giovanni Mettivier, Matilde Costa, Nico Lanconelli, Anna Ianiro, Mariagabriella Pugliese, Maria Quarto, Paolo Russo
The aim of this study is to determine, via measurements on phantoms and Monte Carlo (MC) simulations, the dose distribution of absorbed dose in a cone-beam breast computed tomography scan. The absorbed dose volume distribution was measured inside a polyethylene cylindrical phantom, simulating adipose breast tissue, using LiF:Mg,Ti thermoluminescence dosimeters. A reasonable agreement (between 2 and 8%) between the simulated and measured data was observed. The 3D distribution of absorbed dose was evaluated at 40, 60 and 80 kV in a phantom simulating a pendant breast...
January 10, 2017: Radiation Protection Dosimetry
https://www.readbyqxmd.com/read/28048364/we-fg-207a-01-introduction-to-dedicated-breast-ct-early-studies
#17
S Vedantham
Mammography-based screening has been a valuable imaging tool for the early detection of non-palpable lesions and has contributed to significant reduction in breast cancer associated mortality. However, the breast imaging community recognizes that mammography is not ideal, and in particular is inferior for women with dense breasts. Also, the 2-D projection of a 3-D organ results in tissue superposition contributing to false-positives. The sensitivity of mammography is breast-density dependent. Its sensitivity, especially in dense breasts, is low due to overlapping tissue and the fact that normal breast tissue, benign lesions and breast cancers all have similar "densities", making lesion detection more difficult...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28047813/su-d-209-07-measure-the-average-glandular-dose-of-a-2d-3d-breast-imaging-protocol-using-ge-senoclaire-breast-tomosynthesis-system
#18
Y Liang, A Dutta
PURPOSE: To measure the average glandular dose (AGD) of a 2D+3D breast imaging protocol using GE SenoClaire breast tomosynthesis system. METHODS: This study used a GE SenoClaire breast tomosynthesis unit, a Gammex ACR mammography accreditation phantom, 5 cm thick PMMA phantom, an Unfors RaySafe X2 mammography detector. The breast imaging protocol includes a regular 2D CC view and a 3D MLO view at 45 degree, using AUTO mode. Both ACR phantom and PMMA phantom were scanned under AUTO mode with 10 daN compression to obtain the techniques of 2D CC view, 3D MLO view, and 3D CC view...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28047717/we-fg-207a-02-why-we-need-breast-ct-clinical-perspective
#19
A O'Connell
Mammography-based screening has been a valuable imaging tool for the early detection of non-palpable lesions and has contributed to significant reduction in breast cancer associated mortality. However, the breast imaging community recognizes that mammography is not ideal, and in particular is inferior for women with dense breasts. Also, the 2-D projection of a 3-D organ results in tissue superposition contributing to false-positives. The sensitivity of mammography is breast-density dependent. Its sensitivity, especially in dense breasts, is low due to overlapping tissue and the fact that normal breast tissue, benign lesions and breast cancers all have similar "densities", making lesion detection more difficult...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28047664/we-de-207b-11-implementation-of-size-specific-3d-beam-modulation-filters-on-a-dedicated-breast-ct-platform-using-breast-immobilization
#20
A Hernandez, J Boone
PURPOSE: To implement a 3D beam modulation filter (3D-BMF) in dedicated breast CT (bCT) and develop a method for conforming the patient's breast to a pre-defined shape, optimizing the effects of the filter. This work expands on previous work reporting the methodology for designing a 3D-BMF that can spare unnecessary dose and improve signal equalization at the detector by preferentially filtering the beam in the thinner anterior and peripheral breast regions. METHODS: Effective diameter profiles were measured for 219 segmented bCT images, grouped into volume quintiles, and averaged within each group to represent the range of breast sizes found clinically...
June 2016: Medical Physics
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