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JOURNAL ARTICLE
Xiaoyi Jiang, Kexin Gan, Yuxin Wang, Chao Tao, Xiaojun Liu, Jie Yuan, Zhibin Jin
Conventional B-mode ultrasound imaging has difficulty in delineating homogeneous soft tissues with similar acoustic impedances, as the reflectivity depends on the acoustic impedance at the interface. As a quantitative imaging biomarker sensitive to alteration of biomechanical properties, speed-of-sound (SoS) holds promising potential for tissue and disease differentiation such as delineation of different breast tissue types with similar acoustic impedance. Compared to two-dimensional (2D) SoS images, three-dimensional (3D) volumetric SoS images achieved through a full-angle ultrasound scan can reveal more intricate morphological structures of tissues; however, they generally require a ring transducer...
April 22, 2024: Ultrasonic Imaging
#2
JOURNAL ARTICLE
Gwenny Verfaillie, Jeff Rutten, Yves D'Asseler, Klaus Bacher
Monte Carlo simulations using patient CT images as input are the gold standard to perform patient-specific dosimetry. However, in standard clinical practice patient's CT images are limited to the reconstructed CT scan range. In this study, organ dose calculations were performed with ImpactMC for chest and cardiac CT using whole-body and anatomy-specific voxel models to estimate the accuracy of CT organ doses based on the latter model. When the 3D patient model is limited to the CT scan range, CT organ doses from Monte Carlo simulations are the most accurate for organs entirely in the field of view...
April 18, 2024: Physical and engineering sciences in medicine
#3
JOURNAL ARTICLE
Sébastien Quetin, Boris Bahoric, Farhad Maleki, Shirin A Enger
Monte Carlo (MC) simulations are the benchmark for accurate radiotherapy dose calculations, notably in patient-specific high dose rate brachytherapy (HDR BT), in cases where considering tissue heterogeneities is critical. However, the lengthy computational time limits the practical application of MC simulations. Prior research used Deep Learning (DL) for dose prediction as an alternative to MC simulations. While accurate dose predictions akin to MC were attained, GPU limitations constrained these predictions to large voxels of 3mm × 3mm × 3mm...
April 11, 2024: Physics in Medicine and Biology
#4
JOURNAL ARTICLE
Yunchan Chen, Sophia Arbuiso, Nicholas A Vernice, Grant G Black, Marcos Lu Wang, Matthew W Liao, Samuel J Medina, Kristy A Brown, David Otterburn
INTRODUCTION: Autologous fat grafting is a method of improving aesthetic outcomes after both breast reconstruction and aesthetic surgery through volume enhancement and tissue contouring. Long-lasting effects are linked to greater patient satisfaction and more optimal augmentation results. Harvesting, processing, and injection techniques may all affect the longevity of deformity filling. Our objective is to evaluate the effect of lipoaspirate processing modality on longitudinal volume retention after surgery...
April 1, 2024: Annals of Plastic Surgery
#5
JOURNAL ARTICLE
Haoran Li, Yan Lin, Xiaoyu Zhang, Zhengyao Li, Dali Mu
BACKGROUND: In addition to symptom relief, the crucial objective of reduction mammoplasty is to achieve a stable and esthetically pleasing postoperative breast shape. However, the morphological changes in breasts following reduction mammoplasty have not been comprehensively understood. In this study, we applied three-dimensional (3D) scanning technology for long-term follow-up monitoring of breast morphological changes to discern their changing trends. Our goal was to provide a reliable basis for assessing postoperative effects and determining follow-up time points...
March 29, 2024: Aesthetic Plastic Surgery
#6
JOURNAL ARTICLE
Wiesław Guz, Rafał Podgórski, David Aebisher, Adrian Truszkiewicz, Agnieszka Machorowska-Pieniążek, Grzegorz Cieślar, Aleksandra Kawczyk-Krupka, Dorota Bartusik-Aebisher
The aim of this work was to use and optimize a 1.5 Tesla magnetic resonance imaging (MRI) system for three-dimensional (3D) images of small samples obtained from breast cell cultures in vitro. The basis of this study was to design MRI equipment to enable imaging of MCF-7 breast cancer cell cultures (about 1 million cells) in 1.5 and 2 mL glass tubes and/or bioreactors with an external diameter of less than 20 mm. Additionally, the development of software to calculate longitudinal and transverse relaxation times is described...
March 5, 2024: International Journal of Molecular Sciences
#7
JOURNAL ARTICLE
Shi Bai, Lingke Gai, Qinyang Zhang, Yue Kang, Zhiyao Liu, Yuan He, Wenzhong Liu, Tao Jiang, Zhongzhou Du, Siyao Du, Si Gao, Min Zhang, Tianshu Li
In this study, a novel human-size handheld magnetic particle imaging (MPI) system was developed for the high-precision detection of sentinel lymph nodes for breast cancer. The system consisted of a highly sensitive home-made MPI detection probe, a set of concentric coils pair for spatialization, a solenoid coil for uniform excitation at 8 [email protected] mT, and a full mirrored coil set positioned far away from the scanning area. The mirrored coils formed an extremely effective differential pickup structure which suppressed the system noise as high as 100 dB...
2024: Frontiers in Bioengineering and Biotechnology
#8
JOURNAL ARTICLE
Qi-Long Liu, Kit-Lun Yick, Yue Sun, Joanne Yip
Understanding the dynamic deformation pattern and biomechanical properties of breasts is crucial in various fields, including designing ergonomic bras and customized prostheses, as well as in clinical practice. Previous studies have recorded and analyzed the dynamic behaviors of the breast surface using 4D scanning, which provides a sequence of 3D meshes during movement with high spatial and temporal resolutions. However, these studies are limited by the lack of robust and automated data processing methods which result in limited data coverage or error-prone analysis results...
2024: PloS One
#9
JOURNAL ARTICLE
Á Esteban Hurtado, J Orozco Cortés, P Cárcamo Ibarra, U López González, Á Badenes Romero, M Á Navas de la Cruz, C Siscar Gelo, L Casas Calabuig, P Abreu Sánchez, T Mut Dólera, D Balaguer Muñoz, M D Reyes Ojeda, C Plancha Mansanet, E Caballero Calabuig
INTRODUCTION: Freehand SPECT can be a useful imaging technique for preoperative planning of sentinel lymph node biopsy (SLNB) as it allows localization of the sentinel node by 3D and real-time tomographic imaging and determines its depth after a few minutes of scanning. The aim of the study was to evaluate the correlation between the number of detected SNs between freehand SPECT images and lymphoscintigraphy (LS). MATERIALS AND METHODS: 100 patients with a diagnosis of invasive breast cancer and no clinical evidence of lymph node involvement prospectively underwent SLNB...
February 20, 2024: Revista española de medicina nuclear e imagen molecular
#10
JOURNAL ARTICLE
Bin Hu, Yanjun Xu, Huiling Gong, Lang Tang, Lihong Wang, Hongchang Li
BACKGROUND: In HR+ /HER2- breast cancer patients with ≤ 3 positive axillary lymph nodes (ALNs), genomic tests can streamline chemotherapy decisions. Current studies, centered on tumor metrics, miss broader patient insights. Automated Breast Volume Scanning (ABVS) provides advanced 3D imaging, and its potential synergy with radiomics for ALN evaluation is untapped. OBJECTIVE: This study sought to combine ABVS radiomics and clinical characteristics in a nomogram to predict ≤ 3 positive ALNs in HR+ /HER2- breast cancer patients with 1-2 positive sentinel lymph nodes (SLNs), guiding clinicians in genetic test candidate selection...
February 20, 2024: Academic Radiology
#11
JOURNAL ARTICLE
Chao-Wei Chang, Meng-Chien Hsieh, I-Wen Lin, Rong-Fu Chen, Yur-Ren Kuo, Su-Shin Lee
Accurate assessment of wound areas is crucial in making therapeutic decisions, as the prognosis and changes in the size of the wound over time play a significant role. An ideal assessment method should possess qualities such as speed, affordability, accuracy, user-friendliness for both patients and healthcare professionals, and suitability for daily clinical practice. This study aims to introduce a handheld 3-dimensional (3D) scanner and evaluate its accuracy in measuring wound areas. Engineers from the Industrial Technology Research Institute in Taiwan developed a handheld 3D scanner with the intention of extending its application to the medical field...
February 9, 2024: Medicine (Baltimore)
#12
JOURNAL ARTICLE
In-vitro antimicrobial activity of AF-DP protein and in-silico approach of cell membrane disruption.
Fatemeh Velayatipour, Hossein Tarrahimofrad, Javad Zamani, Fatemeh Fotouhi, Saeed Aminzadeh
Microbial resistance against common antibiotics has become one of the most serious threats to human health. The increasing statistics on this problem show the necessity of finding a way to deal with it. In recent years, antimicrobial peptides with unique properties and the capability of targeting a wide range of pathogens, have been considered as a potential for replacing common antibiotics. A small chitin-binding protein with anticandidal activity was isolated from Moringa oleifera seeds by Neto and colleagues in 2017, which very much resembled antimicrobial peptides...
February 6, 2024: Journal of Biomolecular Structure & Dynamics
#13
Charlotte Sonigo, Geoffroy Robin, Florence Boitrelle, Eloïse Fraison, Nathalie Sermondade, Emmanuelle Mathieu d' Argent, Pierre-Emmanuel Bouet, Charlotte Dupont, Hélène Creux, Maeliss Peigné, Olivier Pirrello, Sabine Trombert, Emmanuel Lecorche, Ludivine Dion, Laurence Rocher, Emmanuel Arama, Valérie Bernard, Margaux Monnet, Laura Miquel, Eva Birsal, Stéphanie Haïm Boukobza, Ingrid Plotton, Célia Ravel, Véronika Grzegorczyk Martin, Eric Huyghe, Hugo G A Dupuis, Tiphaine Lefevre, Florence Leperlier, Léna Bardet, Imane Lalami, Camille Robin, Virginie Simon, Laura Dijols, Justine Riss, Antoine Koch, Clément Bailly, Constance Rio, Marine Lebret, Margaux Jegaden, Hervé Fernandez, Jean-Luc Pouly, Antoine Torre, Jean-Marie Antoine, Blandine Courbiere
OBJECTIVE: To update the 2010 CNGOF clinical practice guidelines for the first-line management of infertile couples. MATERIALS AND METHODS: Five major themes (first-line assessment of the infertile woman, first-line assessment of the infertile man, prevention of exposure to environmental factors, initial management using ovulation induction regimens, first-line reproductive surgery) were identified, enabling 28 questions to be formulated using the PICO (Patients, Intervention, Comparison, Outcome) format...
February 2, 2024: Gynecologie, Obstetrique, Fertilite & Senologie
#14
JOURNAL ARTICLE
Nan Zhang, Qingwei Song, Hongbing Liang, Zhuo Wang, Qi Wu, Haonan Zhang, Lina Zhang, Ailian Liu, Huali Wang, Jiazheng Wang, Liangjie Lin
OBJECTIVE: To examine amide proton transfer-weighted (APTw) combined with diffusion weighed (DWI) and dynamic contrast enhanced (DCE) MRI for early prediction of pathological response to neoadjuvant chemotherapy in invasive breast cancer. MATERIALS: In this prospective study, 50 female breast cancer patients (49.58 ± 10.62 years old) administered neoadjuvant chemotherapy (NAC) were enrolled with MRI carried out both before NAC (T0) and at the end of the second cycle of NAC (T1)...
2024: Frontiers in Medicine
#15
JOURNAL ARTICLE
Deepak Basaula, Barry Hay, Mark Wright, Lisa Hall, Alan Easdon, Peter McWiggan, Adam Yeo, Elena Ungureanu, Tomas Kron
Bolus is commonly used to improve dose distributions in radiotherapy in particular if dose to skin must be optimised such as in breast or head and neck cancer. We are documenting four years of experience with 3D printed bolus at a large cancer centre. In addition to this we review the quality assurance (QA) program developed to support it. More than 2000 boluses were produced between Nov 2018 and Feb 2023 using fused deposition modelling (FDM) printing with polylactic acid (PLA) on up to five Raise 3D printers...
January 29, 2024: Physical and engineering sciences in medicine
#16
JOURNAL ARTICLE
Richard Sidebottom, Donna Webb, Briony Bishop, Kabir Mohammed, Steven Allen
OBJECTIVES: Determine the proportion of breast cancers for which MARIA® findings correspond to the cancer, with stratification by breast density and histological type.Investigate performance in symptomatic lesionsGain patient feedback on experience with MARIA®. METHODS: MARIA® uses a radio frequency antennae array to measure signal attenuation and back scatter to build up a 3D map of tissue dielectric values.The study was a prospective, single-centre, interventional, post-approval device study...
January 24, 2024: British Journal of Radiology
#17
JOURNAL ARTICLE
Xue Li, Jacob Johnson, Roberta M Strigel, Leah C Henze Bancroft, Samuel A Hurley, Iman Zare Estakhraji, Manoj Kumar, Amy M Fowler, Alan B McMillan
OBJECTIVE: Simultaneous PET/MR scanners combine the high sensitivity of MR imaging with the functional imaging of PET. However, attenuation correction of breast PET/MR imaging is technically challenging. The purpose of this study is to establish a robust attenuation correction algorithm for breast PET/MR images that relies on deep learning (DL) to recreate the missing portions of the patient's anatomy (truncation completion), as well as to provide bone information for attenuation correction from only the PET data...
January 22, 2024: Physics in Medicine and Biology
#18
JOURNAL ARTICLE
Giovanni Mettivier, Youfang Lai, Xun Jia, Paolo Russo
To compare the dosimetric performance of three cone-beam breast computed tomography (BCT) scanners, using real-time Monte Carlo-based dose estimates obtained with the VCT-BREAST GPU-accelerated platform dedicated to virtual clinical trials (VCT) in breast imaging.
Approach: A GPU-based Monte Carlo code was developed for replicating in silico the geometric, x-ray spectra and detector setups adopted respectively in two research scanners and one commercial scanner, adopting 80 kV, 60 kV and 49 kV tube voltage, respectively...
January 18, 2024: Physics in Medicine and Biology
#19
JOURNAL ARTICLE
Junhyeok Ock, Sojin Moon, MinKyeong Kim, Beom Seok Ko, Namkug Kim
BACKGROUND AND OBJECTIVES: Although magnetic resonance imaging (MRI) is commonly used for breast tumor detection, significant challenges remain in determining and presenting the three-dimensional (3D) morphology of tumors to guide breast-conserving surgery. To address this challenge, we have developed the augmented reality-breast surgery guide (AR-BSG) and compared its performance with that of a traditional 3D-printed breast surgical guide (3DP-BSG). METHODS: Based on the MRI results of a breast cancer patient, a breast phantom made of skin, body, and tumor was fabricated through 3D printing and silicone-casting...
December 29, 2023: Computer Methods and Programs in Biomedicine
#20
JOURNAL ARTICLE
Xi Bu, Jian-Xun Ma, You-Chen Xia, Bi Li, Yue Lang, Shi-Lu Yin
PURPOSE: Polyacrylamide hydrogel (PAHG), which had been used widely for breast augmentation, has been banned for more than 15 years. Patients who had been injected PAHG for breast augmentation need evacuation surgery to remove as much as possible. To provide a series of diagnosis and treatment process MRI and intraoperative color Doppler ultrasound are combined for maximal removal of PAHG. METHODS: The patients who received evacuation surgery in Peking University Third Hospital from 2010 to 2022 after PAHG injection for breast augmentation were included in this research...
January 2024: Annals of Surgical Treatment and Research
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