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https://www.readbyqxmd.com/read/29775815/simultaneous-magnetic-resonance-and-optical-elastography-acquisitions-comparison-of-displacement-images-and-shear-modulus-estimations-using-a-single-vibration-source
#1
Spencer T Brinker, Steven P Kearney, Thomas J Royston, Dieter Klatt
The mechanical properties of tissue are sensitive to pathological changes, which is the basis for using dynamic elastography as a diagnostic tool. The purpose of this study is a concurrent cross-modality comparison of two dynamic elastography methods, Magnetic Resonance Elastography (MRE) and Scanning Laser Doppler Vibrometry (SLDV) using a single vibration source method. Cylindrical soft tissue mimicking specimens of Plastisol and Ecoflex are stimulated with 60, 100, 150, and 250 Hz sinusoidal vibration during imaging...
May 8, 2018: Journal of the Mechanical Behavior of Biomedical Materials
https://www.readbyqxmd.com/read/29775663/free-breathing-ultrashort-echo-time-lung-magnetic-resonance-imaging-using-stack-of-spirals-acquisition-a-feasibility-study-in-oncology-patients
#2
Min Jae Cha, Hyun Jeong Park, Mun Young Paek, Alto Stemmer, Eun Sun Lee, Sung Bin Park, Yang Soo Kim
OBJECTIVES: To investigate the diagnostic accuracy of lung magnetic resonance imaging (MRI) with a free-breathing three-dimensional ultrashort echo time spoiled gradient echo sequence using a stack-of-spirals acquisition (spiral 3D UTE) for pulmonary nodule detection at 3 T in oncology patients. METHODS: The institutional review board approved this retrospective study. Between June and September of 2017, 32 oncology patients underwent both free-breathing spiral 3D UTE of the lungs and thin-section chest computed tomography (CT) for pulmonary metastasis workups...
May 15, 2018: Magnetic Resonance Imaging
https://www.readbyqxmd.com/read/29774907/plasmon-response-evaluation-based-on-image-derived-arbitrary-nanostructures
#3
S Trautmann, M Richard-Lacroix, A Dathe, H Schneidewind, J Dellith, W Fritzsche, V Deckert
The optical response of realistic 3D plasmonic substrates composed of randomly shaped particles of different size and interparticle distance distributions in addition to nanometer scale surface roughness is intrinsically challenging to simulate due to computational limitations. Here, we present a Finite Element Method (FEM)-based methodology that bridges in-depth theoretical investigations and experimental optical response of plasmonic substrates composed of such silver nanoparticles. Parametrized scanning electron microscopy (SEM) images of surface enhanced Raman spectroscopy (SERS) active substrate and tip-enhanced Raman spectroscopy (TERS) probes are used to simulate the far-and near-field optical response...
May 18, 2018: Nanoscale
https://www.readbyqxmd.com/read/29774634/study-of-hyperpigmentation-in-human-skin-disorder-using-different-electron-microscopy-techniques
#4
Seulgi Noh, Hyosun Choi, Ji Soo Kim, Il-Hwan Kim, Ji Young Mun
There is a global trend of increase in the demand for three-dimensional electron microscopy with high resolution. The ultrastructural change and related functional studies are necessary to investigate biological phenomena. In this study, currently available 3D reconstruction techniques of electron microscopes (serial block-face scanning electron microscopy and focused ion beam-scanning electron microscopy) were used to investigate hyperpigmentary disorders in human skin. In the basal layer of the epidermis in the human skin, there are melanocytes that produce melanin and keratinocytes that act as a barrier against environmental damage...
May 18, 2018: Microscopy Research and Technique
https://www.readbyqxmd.com/read/29774594/in-vivo-characterization-of-3d-skull-and-brain-motion-during-dynamic-head-vibration-using-magnetic-resonance-elastography
#5
Ziying Yin, Yi Sui, Joshua D Trzasko, Phillip J Rossman, Armando Manduca, Richard L Ehman, John Huston
PURPOSE: To introduce newly developed MR elastography (MRE)-based dual-saturation imaging and dual-sensitivity motion encoding schemes to directly measure in vivo skull-brain motion, and to study the skull-brain coupling in volunteers with these approaches. METHODS: Six volunteers were scanned with a high-performance compact 3T-MRI scanner. The skull-brain MRE images were obtained with a dual-saturation imaging where the skull and brain motion were acquired with fat- and water-suppression scans, respectively...
May 17, 2018: Magnetic Resonance in Medicine: Official Journal of the Society of Magnetic Resonance in Medicine
https://www.readbyqxmd.com/read/29771683/an-individualized-strategy-to-estimate-the-effect-of-deformable-registration-uncertainty-on-accumulated-dose-in-the-upper-abdomen
#6
Yibing Wang, Steven F Petit, Eliana Vasquez Osorio, Vikas Gupta, Alejandra Méndez Romero, Ben J M Heijmen
In the abdomen, it is challenging to assess the accuracy of deformable image registration (DIR) for individual patients, due to the lack of clear anatomical landmarks, which can hamper clinical applications that require high accuracy DIR, such as adaptive radiotherapy. In this study, we propose and evaluate a methodology for estimating the impact of uncertainties in DIR on calculated accumulated dose in the upper abdomen, in order to aid decision making in adaptive treatment approaches. 
 Sixteen liver metastasis patients treated with SBRT were evaluated...
May 17, 2018: Physics in Medicine and Biology
https://www.readbyqxmd.com/read/29771086/-design-of-cross-sectional-anatomical-model-focused-on-drainage-pathways-of-paranasal-sinuses
#7
Y Zha, W Lv, Y L Gao, Z Z Zhu, Z Q Gao
Objective: To design and produce cross-sectional anatomical models of paranasal sinuses for the purpose of demonstrating drainage pathways of each nasal sinus for the young doctors. Method: We reconstructed the three-dimensional model of sinuses area based on CT scan data, and divided it into 5 thick cross-sectional anatomy models by 4 coronal plane,which cross middle points of agger nasi cell, ethmoid bulla, posterior ethmoid sinuses and sphenoid sinus respectively. Then a 3D printerwas used to make anatomical cross-sectional anatomical models...
May 2018: Journal of Clinical Otorhinolaryngology, Head, and Neck Surgery
https://www.readbyqxmd.com/read/29770492/accelerated-3d-grase-imaging-improves-quantitative-multiple-post-labeling-delay-arterial-spin-labeling
#8
Markus Boland, Rüdiger Stirnberg, Eberhard D Pracht, Johanna Kramme, Roberto Viviani, Julia Stingl, Tony Stöcker
PURPOSE: To investigate the impact of accelerated, single-shot 3D-GRASE acquisition on quantitative arterial spin labeling (ASL) with multiple and single post-labeling delay (PLD) in terms of perfusion-weighted SNR per unit scan time (TSNRPW ) and quantification accuracy. METHODS: Five subjects were scanned on a 3T MRI scanner using the pseudo-continuous arterial spin labeling (PCASL) technique with a 3D-GRASE imaging sequence capable of parallel imaging acceleration...
May 16, 2018: Magnetic Resonance in Medicine: Official Journal of the Society of Magnetic Resonance in Medicine
https://www.readbyqxmd.com/read/29769114/-68-ga-psma-pet-ct-for-the-evaluation-of-pulmonary-metastases-and-opacities-in-patients-with-prostate-cancer
#9
Jonathan Damjanovic, Jan-Carlo Janssen, Christian Furth, Gerd Diederichs, Thula Walter, Holger Amthauer, Marcus R Makowski
BACKGROUND: The purpose of this study was to investigate the imaging properties of pulmonary metastases and benign opacities in 68 Ga-PSMA positron emission tomography (PET) in patients with prostate cancer (PC). METHODS: 68 Ga-PSMA-PET/CT scans of 739 PC patients available in our database were evaluated retrospectively for lung metastases and non-solid focal pulmonary opacities. Maximum standardized uptake values (SUVmax ) were assessed by two- and three-dimensional regions of interest (2D/3D ROI)...
May 16, 2018: Cancer Imaging: the Official Publication of the International Cancer Imaging Society
https://www.readbyqxmd.com/read/29765199/the-development-of-a-reference-database-with-the-topcon-3d-oct-1-maestro
#10
Michael Chaglasian, Murray Fingeret, Pinakin Gunvant Davey, Wei-Chieh Huang, Danny Leung, Edmund Ng, Charles A Reisman
Importance: The paper presents the range for measurements taken with a new spectral domain optical coherence tomography (OCT) device to establish a reference database for discrimination purposes. Objective: To report the range of thickness values for the new Topcon Maestro 3D OCT device with 2 scan size settings: the 12×9 mm wide field and 6×6 mm scans. Design: Prospective, multicenter cohort study conducted at 7 clinical sites across the USA...
2018: Clinical Ophthalmology
https://www.readbyqxmd.com/read/29765060/iron-specific-signal-separation-from-within-heavy-metal-stained-biological-samples-using-x-ray-microtomography-with-polychromatic-source-and-energy-integrating-detectors
#11
Tsvi Katchalski, Tom Case, Keun-Young Kim, Ranjan Ramachandra, Eric A Bushong, Thomas J Deerinck, Matthias G Haberl, Mason R Mackey, Steven Peltier, Guillaume A Castillon, Nobuko Fujikawa, Albert R Lawrence, Mark H Ellisman
Biological samples are frequently stained with heavy metals in preparation for examining the macro, micro and ultra-structure using X-ray microtomography and electron microscopy. A single X-ray microtomography scan reveals detailed 3D structure based on staining density, yet it lacks both material composition and functional information. Using a commercially available polychromatic X-ray source, energy integrating detectors and a two-scan configuration labelled by their energy- "High" and "Low", we demonstrate how a specific element, here shown with iron, can be detected from a mixture with other heavy metals...
May 15, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29765057/critical-amino-acids-for-the-insecticidal-activity-of-vip3af-from-bacillus-thuringiensis-inference-on-structural-aspects
#12
N Banyuls, C S Hernández-Rodríguez, J Van Rie, J Ferré
Vip3 vegetative insecticidal proteins from Bacillus thuringiensis are an important tool for crop protection against caterpillar pests in IPM strategies. While there is wide consensus on their general mode of action, the details of their mode of action are not completely elucidated and their structure remains unknown. In this work the alanine scanning technique was performed on 558 out of the total of 788 amino acids of the Vip3Af1 protein. From the 558 residue substitutions, 19 impaired protein expression and other 19 substitutions severely compromised the insecticidal activity against Spodoptera frugiperda...
May 15, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29764734/can-the-contralateral-limb-be-used-as-a-control-during-the-growing-period-in-a-rodent-model
#13
Tanvir Mustafy, Irène Londono, Isabelle Villemure
The contralateral limb is often used as a control in various clinical, forensic and anthropological studies. However, no studies have been performed to determine if the contra-lateral limb is a suitable control during the bone development period. The aim of this study was to determine the bilateral symmetry of growing rat tibiae in terms of geometric shape, mechanical strength and bone morphological parameters with developmental stages. Left and right tibias of 18 male Sprague-Dawley rats at 4, 8 and 12 weeks of age were scanned with micro-CT for bone-morphometric evaluation and for 3D deviation analysis to quantify the geometric shape variations between left and right tibiae...
May 12, 2018: Medical Engineering & Physics
https://www.readbyqxmd.com/read/29762319/comparison-of-bone-grafts-from-various-donor-sites-in-human-bone-specimens
#14
Mohammad Kamal, Felix Gremse, Stefanie Rosenhain, Alexander K Bartella, Frank Hölzle, Peter Kessler, Bernd Lethaus
The objective of the current study was to compare the three-dimensional (3D) morphometric microstructure in human cadaveric bone specimens taken from various commonly utilized donor sites for autogenous bone grafting. Autogenous bone grafts can be harvested from various anatomic sites and express heterogeneous bone quality with a specific 3D microstructure for each site. The long-term structural integrity and susceptibility to resorption of the graft depend on the selected donor bone. Micro-computed tomography generates high-resolution datasets of bone structures and calcifications making this modality versatile for microarchitecture analysis and quantification of the bone...
May 14, 2018: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/29762259/precise-and-automatic-patient-positioning-in-computed-tomography-avatar-modeling-of-the-patient-surface-using-a-3-dimensional-camera
#15
Natalia Saltybaeva, Bernhard Schmidt, Andreas Wimmer, Thomas Flohr, Hatem Alkadhi
OBJECTIVES: The aim of this study was to evaluate the accuracy of a 3-dimensional (3D) camera algorithm for automatic and individualized patient positioning based on body surface detection and to compare the results of the 3D camera with manual positioning performed by technologists in routinely obtained chest and abdomen computed tomography (CT) examinations. MATERIALS AND METHODS: This study included data of 120 patients undergoing clinically indicated chest (n = 68) and abdomen (n = 52) CT...
May 14, 2018: Investigative Radiology
https://www.readbyqxmd.com/read/29761690/assessment-of-the-relationship-between-renal-volume-and-renal-function-after-minimally-invasive-partial-nephrectomy-the-role-of-computed-tomography-and-nuclear-renal-scan
#16
Riccardo Bertolo, Cristian Fiori, Federico Piramide, Daniele Amparore, Monica Barrera, Diego Sardo, Andrea Veltri, Francesco Porpiglia
BACKGROUND: To evaluate the correlation between the loss of renal function as assessed by Tc99MAG-3 renal scan and the loss of renal volume as calculated by volumetric assessment on CT-scan in patients who underwent minimally-invasive partial nephrectomy (PN). METHODS: PN prospectively-maintained database was retrospectively queried for patients who underwent minimally-invasive PN (2012-2017) for renal mass <cT2 and had complete data on renal scan and contrast-enhanced CT-scan (both performed in our Institution) both at preoperative assessment and at the third postoperative month follow-up...
May 14, 2018: Minerva Urologica e Nefrologica, the Italian Journal of Urology and Nephrology
https://www.readbyqxmd.com/read/29761595/radiomics-analysis-of-apparent-diffusion-coefficient-in-cervical-cancer-a-preliminary-study-on-histological-grade-evaluation
#17
Ying Liu, Yuwei Zhang, Runfen Cheng, Shichang Liu, Fangyuan Qu, Xiaoyu Yin, Qin Wang, Bohan Xiao, Zhaoxiang Ye
BACKGROUND: The role of apparent diffusion coefficient (ADC)-based radiomics features in evaluating histopathological grade of cervical cancer is unresolved. PURPOSE: To determine if there is a difference between radiomics features derived from center-slice 2D versus whole-tumor volumetric 3D for ADC measurements in patients with cervical cancer regarding tumor histopathological grade, and systematically assess the impact of the b value on radiomics analysis in ADC quantifications...
May 14, 2018: Journal of Magnetic Resonance Imaging: JMRI
https://www.readbyqxmd.com/read/29757163/novel-secondary-assembled-micro-nano-porous-spheres-znco2o4-with-superior-electrochemical-performances-as-lithium-ions-anode-material
#18
Haowen Liu, Qihong Hu
In this work, novel secondary assembled micro/nano porous spheres ZnCo2O4 have been firstly prepared by combining hydrothermal method with post-synthesis calcinations. The structure and morphology of the obtained powder were characterized by X-ray powder diffraction (XRD) and field emission-scanning electron microscopy (FE-SEM). As anode material of lithium-ion half cells, the as-prepared ZnCo2O4 delivered a very high capacity, extra cycling stability and excellent rate capability. A discharge capacity of 950 mAh g-1 with up to 99...
May 14, 2018: Nanotechnology
https://www.readbyqxmd.com/read/29756863/wave-function-hybridization-in-yu-shiba-rusinov-dimers
#19
Michael Ruby, Benjamin W Heinrich, Yang Peng, Felix von Oppen, Katharina J Franke
Magnetic adsorbates on superconductors induce local bound states within the superconducting gap. These Yu-Shiba-Rusinov (YSR) states decay slowly away from the impurity compared to atomic orbitals, even in 3D bulk crystals. Here, we use scanning tunneling spectroscopy to investigate their hybridization between two nearby magnetic Mn adatoms on a superconducting Pb(001) surface. We observe that the hybridization leads to the formation of symmetric and antisymmetric combinations of YSR states. We investigate how the structure of the dimer wave functions and the energy splitting depend on the shape of the underlying monomer orbitals and the orientation of the dimer with respect to the Pb lattice...
April 13, 2018: Physical Review Letters
https://www.readbyqxmd.com/read/29756132/comparison-between-five-cad-cam-systems-for-fit-of-zirconia-copings
#20
Syed Rashid Habib, Asim Khaled Al Otaibi, Talal Ali Al Anazi, Samer Mosleh Al Anazi
OBJECTIVE: The aim of this in-vitro study was to investigate the marginal and internal fit of zirconia copings fabricated by five CAD/CAM (computer-aided design/computer-assisted manufacture) systems. METHOD AND MATERIALS: A typodont mandibular right first molar was prepared according to ideal parameters for a zirconia crown, scanned digitally, and 100 identical resin dies fabricated by 3D printing. Samples were randomly divided into five groups and sent to CAD/CAM systems for zirconia copings (A, Ceramill-Motion 2, Amann Girrbach; B, Weiland, Ivoclar Vivadent; C, Cerec, Ivoclar Vivadent; D, Prettau Zirconia, Zirkonzahn; E, Cad4dent)...
2018: Quintessence International
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