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Bruno Sommacal, Miodrag Savic, Andreas Filippi, Sebastian Kühl, Florian M Thieringer
PURPOSE: To compare the suitability of a fused filament fabrication (FFF) consumer 3D printer with a professional digital light processing (DLP) printer for the production of surgical templates for guided oral implant surgery. MATERIALS AND METHODS: Eight virtual templates were printed with two different 3D printers. These were optically scanned and the incongruences between virtual and printed templates were determined after alignment of the surface scans and the virtual data...
March 15, 2018: International Journal of Oral & Maxillofacial Implants
V A Shaimova, T B Shaimov, R B Shaimov, A Yu Galin, Zh A Goloshchapova, P K Ryzhkov, A V Fomin
PURPOSE: To develop methods for evaluating effectiveness of YAG-laser vitreolysis of vitreous floaters. MATERIAL AND METHODS: The study included 144 patients (173 eyes) who had underwent YAG-laser vitreolysis and were under observation from 01.09.16 to 31.01.18. The patients were 34 to 86 years old (mean age 62.7±10.2 years), 28 (19.4%) patients were male, 116 (80.6%) - female. All patients underwent standard and additional examination: ultrasonography (Accutome B-scan plus, U...
2018: Vestnik Oftalmologii
Thomas Waltemate, Dominik Gall, Daniel Roth, Mario Botsch, Marc Erich Latoschik
This article reports the impact of the degree of personalization and individualization of users' avatars as well as the impact of the degree of immersion on typical psychophysical factors in embodied Virtual Environments. We investigated if and how virtual body ownership (including agency), presence, and emotional response are influenced depending on the specific look of users' avatars, which varied between (1) a generic hand-modeled version, (2) a generic scanned version, and (3) an individualized scanned version...
April 2018: IEEE Transactions on Visualization and Computer Graphics
Valerio Nardone, Paolo Tini, Stefania Croci, Salvatore Francesco Carbone, Lucio Sebaste, Tommaso Carfagno, Giuseppe Battaglia, Pierpaolo Pastina, Giovanni Rubino, Maria Antonietta Mazzei, Luigi Pirtoli
Background: The aim of our work is to assess the potential role of texture analysis (TA), applied to computed tomography (CT) simulation scans, in relation to the development of insufficiency fractures (IFs) in patients undergoing radiation therapy (RT) for pelvic malignancies. Methods: We analyzed patients undergoing pelvic RT from Jan-2010 to Dec-2016, 31 of whom had developed IFs of the pelvis. We analyzed CT simulation scans using LifeX Software© , and in particular we selected three regions of interest (ROI): L5 body, the sacrum and both the femoral heads...
February 2018: Quantitative Imaging in Medicine and Surgery
Iain Rankin, Haroon Rehman, Mark Frame
Background: Traditional ACL reconstruction with non-anatomic techniques can demonstrate unsatisfactory long-term outcomes with regards instability and the degenerative knee changes observed with these results. Anatomic ACL reconstruction attempts to closely reproduce the patient's individual anatomic characteristics with the aim of restoring knee kinematics, in order to improve patient short and long-term outcomes. We designed an arthroscopic, patient-specific, ACL femoral tunnel guide to aid anatomical placement of the ACL graft within the femoral tunnel...
2018: Open Orthopaedics Journal
James L Kingsley, Jeffrey P Bibeau, S Iman Mousavi, Cem Unsal, Zhilu Chen, Xinming Huang, Luis Vidali, Erkan Tüzel
Fluorescence recovery after photobleaching (FRAP) is an important tool used by cell biologists to study the diffusion and binding kinetics of vesicles, proteins, and other molecules in the cytoplasm, nucleus, or cell membrane. Although many FRAP models have been developed over the past decades, the influence of the complex boundaries of 3D cellular geometries on the recovery curves, in conjunction with regions of interest and optical effects (imaging, photobleaching, photoswitching, and scanning), has not been well studied...
March 13, 2018: Biophysical Journal
Wen Shuo Chen, Ling Yu Guo, Chia Chun Tang, Cheng Kang Tsai, Hui Hua Huang, Ting Yu Chin, Mong-Lin Yang, Yui Whei Chen-Yang
In this study, we first synthesized a slow-degrading silica nanofiber (SNF2) through an electrospun solution with an optimized tetraethyl orthosilicate (TEOS) to polyvinyl pyrrolidone (PVP) ratio. Then, laminin-modified SNF2, namely SNF2-AP-S-L, was obtained through a series of chemical reactions to attach the extracellular matrix protein, laminin, to its surface. The SNF2-AP-S-L substrate was characterized by a combination of scanning electron microscopy (SEM), Fourier transform-infrared (FTIR) spectroscopy, nitrogen adsorption/desorption isotherms, and contact angle measurements...
March 14, 2018: Nanomaterials
Wolfgang Michael Schaefer, Daniela Knollmann, Jerome Avondo, Andreas Meyer
AIM: In pulmonary emphysema lung volume reduction procedures (LVRP) can optimize respiratory pump function. Identification of the most affected lobe can be reached using relative lobar volume (relVol) from CT, but this approach disregards the corresponding lobar perfusion. The aim of the study was therefore to establish a new parameter combining relVol from CT and relative perfusion (relPerf) from perfusion SPECT as a single parameter (volume/perfusion ratio (VPR)) to optimize the identification procedure...
February 2018: Nuklearmedizin. Nuclear Medicine
Michael A Luzuriaga, Danielle R Berry, John C Reagan, Ronald A Smaldone, Jeremiah J Gassensmith
Biodegradable polymer microneedle (MN) arrays are an emerging class of transdermal drug delivery devices that promise a painless and sanitary alternative to syringes; however, prototyping bespoke needle architectures is expensive and requires production of new master templates. Here, we present a new microfabrication technique for MNs using fused deposition modeling (FDM) 3D printing using polylactic acid, an FDA approved, renewable, biodegradable, thermoplastic material. We show how this natural degradability can be exploited to overcome a key challenge of FDM 3D printing, in particular the low resolution of these printers...
March 14, 2018: Lab on a Chip
Rania M Fahmy, Ramesa S Bhat, Manar Al-Mutairi, Feda S Aljaser, Afaf El-Ansary
Objective: To evaluate the effect of diabetes mellitus (DM), diabetic retinopathy, and degree of glycemic control (glycosylated hemoglobin [HbA1c]) on peripapillary retinal nerve fiber layer thickness (RNFLT) using optical coherence tomography. Methods: The study included 126 eyes of healthy controls (n=32) and diabetics patients (n=31), whose ages ranged from 40 to 70 years. The diabetic group was divided into: Subgroup 1: with HbA1c <7% and Subgroup 2: with HbA1c ≥7%...
2018: Clinical Ophthalmology
David Anssari Moin, Bassam Hassan, Daniel Wismeijer
PURPOSE: To evaluate the feasibility of a commercially available immediate root analog implant system Replicate (Natural Dental Implants). MATERIALS AND METHODS: Five consecutive patients in need of an implant in the premolar region were recruited for this pilot study. Following clinical examination, a cone beam computed tomography scan was made and the dental impressions digitized. On the basis of the superimposition of these datasets, a three-dimensional (3D) envelope was created for the selected tooth...
March 2018: International Journal of Oral & Maxillofacial Implants
Chanchan Liu, Narayanan Srividya, Amber N Parrish, Wei Yue, Mingqiu Shan, Qinan Wu, B Markus Lange
Schizonepeta tenuifolia Briquet, commonly known as Japanese catnip, is used for the treatment of colds, headaches, fevers, and skin rashes in traditional Asian medicine (China, Japan and Korea). The volatile oil and its constituents have various demonstrated biological activities, but there is currently limited information regarding the site of biosynthesis. Light microscopy and scanning electron microscopy indicated the presence of three distinct glandular trichome types which, based on their morphological features, are referred to as peltate, capitate and digitiform glandular trichomes...
March 10, 2018: Phytochemistry
Lina Xu, Giles Tetteh, Jana Lipkova, Yu Zhao, Hongwei Li, Patrick Christ, Marie Piraud, Andreas Buck, Kuangyu Shi, Bjoern H Menze
The identification of bone lesions is crucial in the diagnostic assessment of multiple myeloma (MM).68 Ga-Pentixafor PET/CT can capture the abnormal molecular expression of CXCR-4 in addition to anatomical changes. However, whole-body detection of dozens of lesions on hybrid imaging is tedious and error prone. It is even more difficult to identify lesions with a large heterogeneity. This study employed deep learning methods to automatically combine characteristics of PET and CT for whole-body MM bone lesion detection in a 3D manner...
2018: Contrast Media & Molecular Imaging
Silvana Fais, Giuseppe Casula, Francesco Cuccuru, Paola Ligas, Maria Giovanna Bianchi
In the following we present a new non-invasive methodology aimed at the diagnosis of stone building materials used in historical buildings and architectural elements. This methodology consists of the integrated sequential application of in situ proximal sensing methodologies such as the 3D Terrestrial Laser Scanner for the 3D modelling of investigated objects together with laboratory and in situ non-invasive multi-techniques acoustic data, preceded by an accurate petrographical study of the investigated stone materials by optical and scanning electron microscopy...
March 12, 2018: Scientific Reports
Selena Tinga, Stanley E Kim, Scott A Banks, Stephen C Jones, Brian H Park, Antonio Pozzi, Daniel D Lewis
BACKGROUND: Cranial cruciate ligament (CrCL) insufficiency is a degenerative condition that is a common cause of pelvic limb lameness and osteoarthritis in dogs. Surgical therapies developed to treat dogs with naturally occurring CrCL insufficiency aim to address the resultant instability, but the in-vivo alterations in stifle kinematics associated with CrCL insufficiency have not been accurately defined. The objective of this study was to quantify the 3-dimensional femorotibial joint kinematics of dogs with naturally occurring cranial cruciate ligament (CrCL) insufficiency during ambulation...
March 12, 2018: BMC Veterinary Research
Antony Orth, Martin Ploschner, Ivan S Maksymov, Brant C Gibson
Compact microendoscopes use multicore optical fibers (MOFs) to visualize hard-to-reach regions of the body. These devices typically have a large numerical aperture (NA) and are fixed-focus, leading to blurry images from a shallow depth of field with little focus control. In this work, we demonstrate a method to digitally adjust the collection aperture and therefore extend the depth of field of lensless MOF imaging probes. We show that the depth of field can be more than doubled for certain spatial frequencies, and observe a resolution enhancement of up to 78% at a distance of 50μm from the MOF facet...
March 5, 2018: Optics Express
Mónica Herrero-Huerta, Roderik Lindenbergh, Wolfgang Gard
Plant leaf movement is induced by some combination of different external and internal stimuli. Detailed geometric characterization of such movement is expected to improve understanding of these mechanisms. A metric high-quality, non-invasive and innovative sensor system to analyze plant movement is Terrestrial LiDAR (TLiDAR). This technique has an active sensor and is, therefore, independent of light conditions, able to obtain accurate high spatial and temporal resolution point clouds. In this study, a movement parameterization approach of leaf plants based on TLiDAR is introduced...
2018: Frontiers in Plant Science
Kimihiro Kajita, Satoshi Goshima, Yoshifumi Noda, Hiroshi Kawada, Nobuyuki Kawai, Tomoyuki Okuaki, Masatoshi Honda, Masayuki Matsuo
PURPOSE: To compare four free-breathing scan techniques for gadoxetic acid-enhanced hepatobiliary phase imaging with conventional breath-hold scans. MATERIALS AND METHODS: Gadoxetic acid-enhanced hepatobiliary phase imaging with six image acquisition sets performed in 50 patients. Image acquisition sets included fat-suppressed 3D T1 -weighted turbo field echo with free-breathing pseudo-golden-angle radial stack-of-stars (FBRS) acquisition, FBRS with track (FBRST ), FBRS with gate and track (FBRSG&T ), thin-slice FBRS with gate and track (thin-slice FBRSG&T ), free-breathing Cartesian acquisition (CartesianFB ), and breath-hold Cartesian acquisition (CartesianBH )...
March 9, 2018: Magnetic Resonance in Medical Sciences: MRMS
Tomislav A Zrnc, Jürgen Wallner, Wolfgang Zemann, Mauro Pau, Christian Gstettner, Luka Brcic, Alexandre T Assaf, Hamid Hassanzadeh, Matthias Feichtinger, Katja Schwenzer-Zimmerer
OBJECTIVES: Determination of tumor margins in patients with squamous cell carcinoma of the head and neck (SCCHN) is mostly based on preoperative magnetic resonance imaging (MRI) or computed tomography scans (CT). Local recurrence of disease is often correlated with the presence of positive resection margins after surgical treatment. Positron emission tomography/computed tomography (PET/CT) imaging plays a crucial role in the assessment of patients with SCCHN. The purpose of this study was to determine whether PET/CT could predict tumor extension...
February 19, 2018: Journal of Cranio-maxillo-facial Surgery
Carolyn Kincade, Lindsay McHutchion, Johan Wolfaardt
The present report describes the digital design of patient-specific milled abutments for the retention of osseointegrated facial prostheses by using digital technology. Patient imaging including surface scans of the patient's head, scans of the patient's definitive cast, and digitally designed prosthesis prototypes were combined to create a digital simulation of the patient. Using this simulation, patient-specific abutments were digitally designed, printed in 3-dimensions (3D), and finally copy-milled in titanium...
March 8, 2018: Journal of Prosthetic Dentistry
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