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https://www.readbyqxmd.com/read/29352330/relationship-between-power-duration-parameters-and-mechanical-and-anthropometric-properties-of-the-thigh-in-elite-cyclists
#1
Mehdi Kordi, Campbell Menzies, Len Parker Simpson
PURPOSE: The curvature constant (W') and asymptote (critical power; CP) of the power-duration relationship are important parameters for explaining cycling performance. Short-duration endurance cycling events rely more heavily on the W'; however, the full mechanistic underpinning of this parameter is yet to be determined. Evidence suggests both muscle volume and muscle strength may contribute to the magnitude of W'. Therefore, the present study investigated the relationship between power-duration parameters (CP and W') and (1) anthropometric and (2) mechanical properties of thigh muscles in a sample of elite cyclists...
January 19, 2018: European Journal of Applied Physiology
https://www.readbyqxmd.com/read/29348315/whole-body-biodistribution-and-dosimetry-of-the-dopamine-transporter-radioligand-18f-fe-pe2i-in-human-subjects
#2
Helena Lizana, Lennart Johansson, Jan E Axelsson, Anne Larsson Strömvall, Mattias Ögren, Jan Linder, Christer Halldin, Andrea Varrone, Susanna Jakobson Mo
18F-(E)-N-(3-iodoprop-2-enyl)-2β-carbofluoroethoxy-3β-(4'-methyl-phenyl) nortropane (18F-FE-PE2I) was recently developed and has shown adequate affinity and high selectivity for the dopamine transporter (DAT). Previous studies have shown promising results for 18F-FE-PE2I as a suitable radioligand for DAT-imaging. In this study, we investigate the whole body biodistribution and dosimetry of 18F-FE-PE2I in healthy volunteers to support the utility of it as a suitable positron emission tomography (PET) imaging agent for the DAT...
January 18, 2018: Journal of Nuclear Medicine: Official Publication, Society of Nuclear Medicine
https://www.readbyqxmd.com/read/29297232/dosimetric-quantification-of-the-incidental-irradiation-of-the-true-deep-ano-inguinal-lymphatic-drainage-of-anal-cancer-patients-not-described-in-conventional-contouring-guidelines
#3
Hendrik Dapper, Gregor Habl, Christoph Hirche, Stefan Münch, Markus Oechsner, Michael Mayinger, Christina Sauter, Stephanie E Combs, Daniel Habermehl
INTRODUCTION: The ano-inguinal lymphatic drainage (AILD) is located in the subcutaneous adipose tissue of the proximal medial thigh. Findings from fluorescence methods give us new information about anatomical conditions of the AILD. Current contouring guidelines do not advise the inclusion of the 'true' AILD into the clinical target volume (CTV). Aim of this work was the retrospective analysis of the incidental dose to the AILD in an anal cancer (AC) patient cohort who underwent definitive chemoradiation (CRT) therapy with Volumetric Arc Therapy - Intensity Modulated Radiation Therapy (VMAT-IMRT)...
January 3, 2018: Acta Oncologica
https://www.readbyqxmd.com/read/29261091/association-of-enterococcus-spp-with-severe-combat-extremity-injury-intensive-care-and-polymicrobial-wound-infection
#4
Rae A Heitkamp, Ping Li, Katrin Mende, Samandra T Demons, David R Tribble, Stuart D Tyner
BACKGROUND: Combat-related extremity wound infections can complicate the recovery of injured military personnel. The Enterococcus genus contains both commensal and pathogenic bacteria found in many combat wounds. We describe the patient population susceptible to Enterococcus infection, the characteristics of Enterococcus spp. isolated from combat-related wounds, and the microbiological profile of Enterococcus-positive wounds. METHODS: Patient and culture data were obtained from the Trauma Infectious Disease Outcomes Study...
December 20, 2017: Surgical Infections
https://www.readbyqxmd.com/read/29245293/association-of-tourniquet-utilization-with-blood-loss-rehabilitation-and-complications-in-chinese-obese-patients-undergoing-total-knee-arthroplasty-a-retrospective-study
#5
Zhirui Li, Daohong Liu, Gong Long, Gong Ke, An Xiao, Peifu Tang, Jiyuan Dong
Obesity not only gives rise to more blood loss volume but also correlates with postoperative rehabilitation and complications in surgical patients. It is not clear at present whether tourniquet utilization is associated with blood loss, rehabilitation, and complications, and it is imperative to ascertain the tactics of utilizing tourniquet in obese patients undergoing total knee arthroplasty (TKA). The present study was designed to explore the association of tourniquet utilization with blood loss, rehabilitation, and complications, and ascertain the tactics of utilizing tourniquet in obese patients undergoing TKA...
December 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29239712/multiparametric-mr-imaging-of-age-related-changes-in-healthy-thigh-muscles
#6
Min A Yoon, Suk-Joo Hong, Min Cheol Ku, Chang Ho Kang, Kyung-Sik Ahn, Baek Hyun Kim
Purpose To use multiparametric magnetic resonance (MR) imaging to assess for and establish age-related differences in healthy thigh muscles. Materials and Methods Ninety-five subjects (47 men, 48 women; median age, 47 years) with healthy body mass index were grouped according to age: 30-39 years (n = 25), 40-49 years (n = 25), 50-59 years (n = 25), and 60-69 years (n = 20). Multiparametric MR imaging (intravoxel incoherent motion diffusion-weighted, diffusion-tensor, multiecho Dixon, and dynamic contrast material-enhanced MR imaging) was performed at 3...
December 14, 2017: Radiology
https://www.readbyqxmd.com/read/29234544/impact-of-transobturator-vaginal-tape-on-female-stress-urinary-incontinence-and-sexual-function
#7
Tarek Soliman, Hammouda Sherif, Abdallah Fathi, Wael Kandeel, Osama Abdelwahab
Objective: To evaluate the effect of vaginal transobturator tape (TOT) on female stress urinary incontinence (SUI) and sexual function. Patients and methods: In all, 145 patients with SUI underwent TOT repair using the 'outside-in' technique. All patients had been sexually active in the previous 6 months. Patients were evaluated by history, routine laboratory investigations, cough stress test, abdominopelvic ultrasonography, and full urodynamic studies. The preoperative data assessed included: age, parity, body mass index, menopausal status, and Stamey grade of SUI...
December 2017: Arab Journal of Urology
https://www.readbyqxmd.com/read/29222689/long-term-quantitative-evaluation-of-muscle-and-bone-wasting-induced-by-botulinum-toxin-in-mice-using-microcomputed-tomography
#8
Hélène Libouban, Claude Guintard, Nicolas Minier, Eric Aguado, Daniel Chappard
Muscle and bone masses are highly correlated and muscles impose large loads on bone. Muscle wasting that accompanies bone loss has been poorly investigated. 21 female mice were spread into seven groups. At day 0, 18 mice received Botulinum toxin (BTX) injection in the quadriceps muscle to induce paralysis of the right hind limb; the left contralateral side was used as control. Mice were sacrificed at 7, 14, 21, 28, 56 and 90 days post-injection. A remaining group was sacrificed at day 0. Trabecular bone volume was determined by microcomputed tomography (microCT) at the distal femur and tibia proximal metaphyses on both sides...
December 8, 2017: Calcified Tissue International
https://www.readbyqxmd.com/read/29212436/estimation-of-individual-thigh-muscle-volumes-from-a-single-slice-muscle-cross-sectional-area-and-muscle-thickness-using-magnetic-resonance-imaging-in-patients-with-knee-osteoarthritis
#9
Koun Yamauchi, Akito Yoshiko, Shigetoshi Suzuki, Chisato Kato, Hiroshi Akima, Takayuki Kato, Koji Ishida
PURPOSE: This study aimed to identify the best single-slice anatomical muscle cross-sectional area (CSA) and muscle thickness (MT) on magnetic resonance imaging (MRI) to estimate the overall individual muscle volumes (MVs) of knee extensors and flexors in patients with knee osteoarthritis (KOA). METHODS: Twelve patients (24 legs; 4 men and 8 women) with KOA underwent a 1.5-Tesla axial MRI scan in the femoral region of interest (ROI), between the lesser trochanter and rectus femoris tendon...
September 2017: Journal of Orthopaedic Surgery
https://www.readbyqxmd.com/read/29205802/a-two-center-assessor-blinded-prospective-trial-evaluating-the-efficacy-of-a-novel-hypertonic-draining-cream-for-cellulite-reduction-a-clinical-and-instrumental-antera-3d-cs-assessment
#10
Mario Puviani, Federica Tovecci, Massimo Milani
INTRODUCTION: Gynoid lipodystrophy, also known as cellulite, is a very common skin alteration representing mainly a cosmetic problem rather than a real disease. An effective treatment of cellulite has not been well established. The initial phase of cellulite is characterized by subdermal tissue edema with interstitial fluids retention. A new hypertonic topical product with draining action (HTC) containing NaCl 13%, escine, caffeine, and beta-sitosterol has been recently developed. A 28-day double-blind placebo-controlled study has shown that this cream is able to reduce thigh circumference and the thickness of adipose tissue...
December 4, 2017: Journal of Cosmetic Dermatology
https://www.readbyqxmd.com/read/29200094/characteristics-of-a-national-level-female-weightlifter-peaking-for-competition-a-case-study
#11
Caleb D Bazyler, Satoshi Mizuguchi, Michael C Zourdos, Kimitake Sato, Ashley A Kavanaugh, Brad H DeWeese, Kevin F Breuel, Michael H Stone
This study investigated physiological and performance changes of a national level 69kg female weightlifter following three competition phases over a 28-week training period. The athlete first trained for a regional championship (weeks 1-12), followed by a local competition (weeks 13-23) and the national championship (weeks 24-28). Body mass, vastus lateralis cross-sectional area, and unloaded and loaded squat jump performance were assessed weekly during each 4-week competition phase. Serum biomarkers, and dynamic mid-thigh pulls were assessed prior to and after each competition phase...
December 1, 2017: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/29197986/relationships-between-mri-fat-distributions-and-sleep-apnea-and-obesity-hypoventilation-syndrome-in-very-obese-patients
#12
C D Turnbull, S H Wang, A R Manuel, B T Keenan, A G McIntyre, R J Schwab, J R Stradling
PURPOSE: Obesity is associated with both obstructive sleep apnea (OSA) and obesity hypoventilation. Differences in adipose tissue distribution are thought to underlie the development of both OSA and hypoventilation. We explored the relationships between the distribution of upper airway, neck, chest, abdominal and muscle fat in very obese individuals. METHODS: We conducted a cross-sectional cohort study of individuals presenting to a tertiary sleep clinic or for assessment for bariatric surgery...
December 2, 2017: Sleep & Breathing, Schlaf & Atmung
https://www.readbyqxmd.com/read/29194976/the-effect-of-adjuvant-radiotherapy-on-radial-forearm-free-flap-volume-after-soft-palate-reconstruction-in-13-patients
#13
Georg Haymerle, Elisabeth Enzenhofer, Wolfgang Lechner, Markus Stock, Annemarie Schratter-Sehn, Erich Vyskocil, Barbara Bachtiary, Edgar Selzer, Boban M Erovic
Treatment options for squamous cell carcinoma of the soft palate include surgical resection followed by radiotherapy or primary radiotherapy. In most cases sufficient resection margins require reconstruction of the defect with free flaps. The most common flaps used in oropharyngeal carcinoma are the radial forearm free flap and the anterolateral thigh and latissimus dorsi free flap. According to the magnitude of the resection defect, surgeons estimate the size and volume of soft tissue transfer needed for an optimal esthetic and in particular functional outcome...
December 1, 2017: Clinical Otolaryngology
https://www.readbyqxmd.com/read/29170306/9%C3%A2-closed-chest-compressions-reduce-survival-in-a-model-of-haemorrhage-induced-traumatic-cardiac-arrest
#14
Sarah Watts, Jason Smith, Robert Gwyther, Emrys Kirkman
BACKGROUND: Closed chest compressions (CCC) are a key component of resuscitation from medical causes of cardiac arrest, but when haemorrhage, the leading cause of preventable battlefield deaths, is the likely cause there is little evidence to support their use. Resuscitation protocols for traumatic cardiac arrest (TCA) highlight the importance of addressing reversible causes, such as the administration of fluids to treat hypovolaemia. This study evaluated whether CCC were beneficial following haemorrhage-induced TCA and additionally whether resuscitation with blood improved physiological outcomes...
December 2017: Emergency Medicine Journal: EMJ
https://www.readbyqxmd.com/read/29140186/acute-effect-of-two-self-myofascial-release-protocols-on-hip-and-ankle-range-of-motion
#15
Amandda de Souza, Cristiano Gomes Sanchotene, Cristiano Moreira da Silva Lopes, Jader Alfredo Beck, Affonso Celso Kulevicz da Silva, Suzana Matheus Pereira, Caroline Ruschel
CONTEXT: Self-myofascial release (SMR) is an intervention popularly used by rehabilitation, fitness, and sports professionals to improve recovery and performance. In SMR, the athlete/patient himself applies pressure to the muscle and fascia, using various tools such as balls, rods, foam rolls and massagers. OBJECTIVE: This study aimed to evaluate the acute effect of two SMR protocols (short- and long-term) of the posterior thigh and calf muscles on hip and ankle range of motion (ROM) in physically active men...
November 15, 2017: Journal of Sport Rehabilitation
https://www.readbyqxmd.com/read/29137681/influence-of-tourniquet-use-in-primary-total-knee-arthroplasty-with-drainage-a-prospective-randomised-controlled-trial
#16
Kai Zhou, Tingxian Ling, Haoyang Wang, Zongke Zhou, Bin Shen, Jing Yang, Pengde Kang, Fuxing Pei
BACKGROUND: We aimed to compare the effect of tourniquet use or lack of it on recovery following uncomplicated primary total knee arthroplasty (TKA). METHODS: In a prospective randomised double-blinded study, 150 patients undergoing primary TKA were assigned to either a tourniquet or non-tourniquet group. At the early phase, 3 and 6 months after surgery, an independent observer assessed the primary outcome measure (i.e. total blood loss) and secondary outcome measures (i...
November 14, 2017: Journal of Orthopaedic Surgery and Research
https://www.readbyqxmd.com/read/29105276/quadriceps-muscle-fat-infiltration-is-associated-with-cardiometabolic-risk-in-copd
#17
Isabelle Vivodtzev, Luc Moncharmont, Renaud Tamisier, Jean-Christian Borel, François Arbib, Bernard Wuyam, Patrick Lévy, François Maltais, Gilbert Ferretti, Jean-Louis Pépin
PURPOSE: Losses of peripheral muscle mass and ectopic fat accumulation have been associated with cardiometabolic morbidity in COPD. We aimed at identifying the relationship between quadriceps muscle fat infiltration and cardiovascular risk. MATERIALS AND METHODS: From 2009 to 2014, 78 COPD patients (64 ± 8 years; 80% male) were prospectively included after having given written consent (ethical committee approval number: 2006-A00491-50). The cohort was divided into three groups (tertiles) according to body mass index (BMI), low [15 < BMI≤23·3], middle [23·3 < BMI≤27·6] and high [27·6 < BMI≤36] kg/m²)...
November 3, 2017: Clinical Physiology and Functional Imaging
https://www.readbyqxmd.com/read/29076327/autogenous-fat-grafting-for-mild-to-moderate-postoperative-temporal-hollowing-after-decompressive-craniectomy-1-year-follow-up
#18
Jaemin Choi, Hyungon Choi, Donghyeok Shin, Jeenam Kim, Myungchul Lee, Soonheum Kim, Dongin Jo, Cheolkeun Kim
>Background: Temporal hollowing is inevitable after decompressive craniectomy. This complication affects self- perception and quality of life, and various techniques and materials have therefore been used to restore patients' confidence. Autologous fat grafting in postoperative scar tissue has been considered challenging because of the hostile tissue environment. However, in this study, we demonstrate that autologous fat grafting can be a simple and safe treatment of choice, even for postoperative depressed temporal scar tissue...
October 27, 2017: Archives of Plastic Surgery
https://www.readbyqxmd.com/read/29064925/lower-extremity-free-flaps-for-breast-reconstruction
#19
REVIEW
Joseph H Dayan, Robert J Allen
Thigh-based flaps are typically a secondary option for breast reconstruction because of concerns regarding limited tissue volume and donor-site morbidity. In recent years, there have been a number of new techniques and insights that have resulted in greater flexibility and improved outcomes. This article reviews lessons learned from a large collective experience using the following 4 flaps: transverse upper gracilis also known as transverse myocutaneous gracilis, diagonal upper gracilis, profunda artery perforator, and lateral thigh perforator flaps...
November 2017: Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/29016531/myocardial-preload-alters-central-pressure-augmentation-through-changes-in-the-forward-wave
#20
Lennart van de Velde, Daan W Eeftinck Schattenkerk, Pascale A H T Venema, Hendrik J Best, Bas van den Bogaard, Wim J Stok, Berend E Westerhof, Bert Jan H van den Born
OBJECTIVE: Augmentation index (AIx) is often used to quantify the contribution of wave reflection to central pulse pressure. Recent studies have challenged this view by showing how contractility-induced changes in the forward pressure wave can markedly impact AIx. We hypothesized that changes in preload will also affect AIx through changes in the forward wave and studied this in two experiments. METHODS: Noninvasively obtained aortic pressure was used to study central haemodynamics and wave morphology...
October 7, 2017: Journal of Hypertension
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