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Lithium health

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https://www.readbyqxmd.com/read/28938233/no-apparent-association-between-bipolar-disorder-and-cancer-in-a-large-epidemiological-study-of-outpatients-in-a-managed-care-population
#1
Natan R Kahan, Barbara Silverman, Irena Liphshitz, Dan-Andrei Waitman, Itzhak Ben-Zion, Alexander M Ponizovsky, Abraham Weizman, Alexander Grinshpoon
An association between bipolar disorder (BD) and cancer risk has been reported. The purpose of this study was to investigate this association through linkage analysis of a national HMO database and a national cancer registry. All members of the Leumit Health Services (LHS) HMO of Israel from 2000 to 2012 were included. Members with a recorded diagnosis of BD and a record of at least one written or dispensed prescription for pharmacotherapy for treatment of BD were classified as patients with BD. We linked the LHS population with the Israel National Cancer Registry database to capture all cases of cancer reported...
September 21, 2017: International Clinical Psychopharmacology
https://www.readbyqxmd.com/read/28809398/precision-medicine-for-suicidality-from-universality-to-subtypes-and-personalization
#2
A B Niculescu, H Le-Niculescu, D F Levey, P L Phalen, H L Dainton, K Roseberry, E M Niculescu, J O Niezer, A Williams, D L Graham, T J Jones, V Venugopal, A Ballew, M Yard, T Gelbart, S M Kurian, A Shekhar, N J Schork, G E Sandusky, D R Salomon
Suicide remains a clear, present and increasing public health problem, despite being a potentially preventable tragedy. Its incidence is particularly high in people with overt or un(der)diagnosed psychiatric disorders. Objective and precise identification of individuals at risk, ways of monitoring response to treatments and novel preventive therapeutics need to be discovered, employed and widely deployed. We sought to investigate whether blood gene expression biomarkers for suicide (that is, a 'liquid biopsy' approach) can be identified that are more universal in nature, working across psychiatric diagnoses and genders, using larger cohorts than in previous studies...
September 2017: Molecular Psychiatry
https://www.readbyqxmd.com/read/28767208/lithium-use-but-not-valproate-use-is-associated-with-a-higher-risk-of-chronic-kidney-disease-in-older-adults-with-mental-illness
#3
Soham Rej, Nathan Herrmann, Kenneth Shulman, Hadas D Fischer, Kinwah Fung, Ziv Harel, Andrea Gruneir
OBJECTIVE: Lithium is an essential mood disorder treatment; however, it remains unclear whether lithium increases chronic kidney disease (CKD) risk. There are few data on this in the elderly, even though older adults may be particularly susceptible to CKD. We wished to determine whether lithium is associated with increased CKD risk relative to valproate in older adults. METHODS: This nested case-control study analyzed province-wide administrative health data from mental health service users aged ≥ 66 years in Ontario, Canada, from 2003 to 2014...
August 1, 2017: Journal of Clinical Psychiatry
https://www.readbyqxmd.com/read/28761912/risk-factors-accelerating-hypothyroidism-in-pregnant-women-referred-to-health-centers-in-abadan-iran
#4
Mahboobeh Momtazan, Mohammad Javad Mohammadi, Raha Tabahfar, Soraya Rezaee, Aliasghar Valipour, Fatemeh Jamei, Ahmad Reza Yari, Azimeh Karimyan, Sahar Geravandi
The present work contains data obtained during the analysis of pregnant women referred to Abadan Health Centers Organization (Abadan HCO) with confirmed acute hypothyroidism diagnosis. From among all pregnant women referred to Abadan HCO, 600 were chosen consisting of 120 pregnant women from each of the health centers in quintuple areas. In this paper, the effects of family history, occupation, death, abortion, type of diabetes, smoking, lithium consumption, allergy, radiotherapy, ovarian cysts (OC) and oral contraceptive pills (OCP) consumption have been studied (Yassaee et al...
October 2017: Data in Brief
https://www.readbyqxmd.com/read/28758250/thermal-injury-caused-by-the-explosion-of-a-lithium-ion-mobile-phone-battery
#5
Monica Corazza, Riccardo Forconi, Dario Musmeci, Giulia Toni, Alessandro Borghi
Mobile phones are part of everyday life. They are generally considered safe for our health, but they may sometimes elicit contact dermatitis, especially due to metals. Furthermore they are under investigation for being involved in the development of defective testicular function and gliomas. This article is protected by copyright. All rights reserved.
July 31, 2017: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/28755622/trajectories-of-suicidal-ideation-over-6-months-among-482-outpatients-with-bipolar-disorder
#6
Ole Köhler-Forsberg, Trine Madsen, Ida Behrendt-Møller, Louisa Sylvia, Charles L Bowden, Keming Gao, William V Bobo, Madhukar H Trivedi, Joseph R Calabrese, Michael Thase, Richard C Shelton, Melvin McInnis, Mauricio Tohen, Terence A Ketter, Edward S Friedman, Thilo Deckersbach, Susan L McElroy, Noreen A Reilly-Harrington, Andrew A Nierenberg
INTRODUCTION: Suicidal ideation occurs frequently among individuals with bipolar disorder; however, its course and persistence over time remains unclear. We aimed to investigate 6-months trajectories of suicidal ideation among adults with bipolar disorder. METHODS: The Bipolar CHOICE study randomized 482 outpatients with bipolar disorder to 6 months of lithium- or quetiapine-based treatment including other psychotropic medications as clinically indicated. Participants were asked at 9 visits about suicidal ideation using the Concise Health Risk Tracking scale...
July 20, 2017: Journal of Affective Disorders
https://www.readbyqxmd.com/read/28725147/shortage-of-psychotropic-medications-in-community-pharmacies-in-saudi-arabia-causes-and-solutions
#7
Yazed Sulaiman Al-Ruthia, Wael Mansy, Mohammad Barasin, Yazeed Mohammad Ghawaa, Mohammed AlSultan, Mohammad A Alsenaidy, Solaiman Alhawas, Sultan AlGhadeer
Background: Patients with mental disorders, such as depression and anxiety, who seek medical care in private psychiatric clinics in Riyadh, Saudi Arabia, have recently expressed concerns to doctors about difficulty in filling psychotropic medications, such as Amitriptyline and Aripiprazole, at retail community pharmacies. Objectives: The aim of this study was to investigate whether there is a shortage of some commonly prescribed psychotropic medications in retail community pharmacies in Saudi Arabia, and if so, to explore the possible reasons behind the shortage of these medications...
July 2017: Saudi Pharmaceutical Journal: SPJ: the Official Publication of the Saudi Pharmaceutical Society
https://www.readbyqxmd.com/read/28650136/platform-switching-and-super-short-implants-an-effective-technique-to-manage-residual-jaws-bone-volume
#8
Graziano Montaruli, Michele Laurenziello, Lucio Lo Russo, Luigi Laino, Lorenzo Lo Muzio, Domenico Ciavarella
INTRODUCTION: Authors describe and analyze an implant-prosthetic rehabilitation of posterior partially edentulous jaw by using a super-short implant, according to the platform switching technique, on which a lithium disilicate made crown was cemented. METHODS: One event of partially edentulous jaw in 2.6 region needing implant-prosthetic rehabilitationwas selected for this treatment. Because of the lack of vertical bone, a super-short implant (6mm in diameter and 6mm in length) has been placed according to the platform switching technique by using surgical and prosthetic components lower in diameter compared to the diameter of the implant's platform...
June 23, 2017: Minerva Stomatologica
https://www.readbyqxmd.com/read/28629296/atypical-antipsychotic-use-and-outcomes-in-an-urban-maternal-mental-health-service
#9
Susan Hatters Friedman, Charmian Moller-Olsen, Chandni Prakash, Abigail North
Objective Despite many women suffering from psychosis in their childbearing years, limited data exist about the use of atypical antipsychotic agents in pregnancy. Atypical antipsychotic agents are often used to treat bipolar disorder, instead of lithium or valproate because of the known teratogenicity of those agents. As well, atypical antipsychotics are often prescribed in anxiety disorders and depression. This study sought to describe pregnancy outcomes for women prescribed atypical antipsychotics during pregnancy...
August 2016: International Journal of Psychiatry in Medicine
https://www.readbyqxmd.com/read/28617151/lithium-exposure-during-pregnancy-outcomes-for-women-who-attended-a-specialist-antenatal-clinic
#10
Jacqueline Frayne, Thinh Nguyen, Tabitha Mok, Yvonne Hauck, Helena Liira
INTRODUCTION: Lithium treatment in pregnancy represents a significant dilemma for women and treating health professionals alike. The complexity of risk-benefit analysis is impacted by limited information. METHODS: A cohort study of 33 women with severe mental illness, who were prescribed lithium at any time during the pregnancy, and gave birth between December 2007 and January 2015 at a specialist antenatal clinic in Western Australia. A descriptive comparison for women who continued lithium throughout pregnancy, and those who ceased on discovery of pregnancy was undertaken examining demographic, obstetric, neonatal and psychiatric variables...
June 15, 2017: Journal of Psychosomatic Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/28608435/cad-cam-fabricated-ceramic-implant-supported-single-crowns-made-from-lithium-disilicate-final-results-of-a-5-year-prospective-cohort-study
#11
Benedikt Christopher Spies, Stefano Pieralli, Kirstin Vach, Ralf-Joachim Kohal
BACKGROUND: All-ceramic bilayer systems suffer from technique-sensitivity, resulting in increased technical complication rates. This might be overcome by monolithic reconstructions, facilitating digital workflows. PURPOSE: To evaluate the clinical and patient-reported outcome of CAD/CAM-fabricated implant-supported single crowns (ISCs) made of lithium disilicate (LS2 ) cemented on ceramic implants 5 years after implant installation. MATERIALS AND METHODS: Twenty-four patients were included in the study...
June 13, 2017: Clinical Implant Dentistry and related Research
https://www.readbyqxmd.com/read/28604590/lithium-in-drinking-water-and-incidence-of-suicide-a-nationwide-individual-level-cohort-study-with-22-years-of-follow-up
#12
Nikoline N Knudsen, Jörg Schullehner, Birgitte Hansen, Lisbeth F Jørgensen, Søren M Kristiansen, Denitza D Voutchkova, Thomas A Gerds, Per K Andersen, Kristine Bihrmann, Morten Grønbæk, Lars V Kessing, Annette K Ersbøll
Suicide is a major public health concern. High-dose lithium is used to stabilize mood and prevent suicide in patients with affective disorders. Lithium occurs naturally in drinking water worldwide in much lower doses, but with large geographical variation. Several studies conducted at an aggregate level have suggested an association between lithium in drinking water and a reduced risk of suicide; however, a causal relation is uncertain. Individual-level register-based data on the entire Danish adult population (3...
June 10, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/28595491/suicidal-behavior-during-lithium-and-valproate-treatment-a-within-individual-8-year-prospective-study-of-50-000-patients-with-bipolar-disorder
#13
COMPARATIVE STUDY
Jie Song, Arvid Sjölander, Erik Joas, Sarah E Bergen, Bo Runeson, Henrik Larsson, Mikael Landén, Paul Lichtenstein
OBJECTIVE: Conclusions regarding lithium's antisuicidal effect for bipolar disorder have been limited due to nonrepresentative subjects and potential confounding factors, including varying severity of illness. Findings regarding the effect of valproate, the most common alternative to lithium, are inconsistent for suicidal behavior. This study investigated the associations of these two drugs with the risk of suicide-related events, and possible differences between drugs, by using within-individual designs in a register-based longitudinal cohort...
August 1, 2017: American Journal of Psychiatry
https://www.readbyqxmd.com/read/28591541/lithium-use-in-pregnancy-and-the-risk-of-cardiac-malformations
#14
COMPARATIVE STUDY
Elisabetta Patorno, Krista F Huybrechts, Brian T Bateman, Jacqueline M Cohen, Rishi J Desai, Helen Mogun, Lee S Cohen, Sonia Hernandez-Diaz
BACKGROUND: There has been concern that exposure to lithium early in pregnancy may be associated with a marked increase in the risk of Ebstein's anomaly (a right ventricular outflow tract obstruction defect) in infants and overall congenital cardiac defects, but data are conflicting and limited. METHODS: We conducted a cohort study involving 1,325,563 pregnancies in women who were enrolled in Medicaid and who delivered a live-born infant between 2000 and 2010. We examined the risk of cardiac malformations among infants exposed to lithium during the first trimester as compared with unexposed infants and, in secondary analyses, with infants exposed to another commonly used mood stabilizer, lamotrigine...
June 8, 2017: New England Journal of Medicine
https://www.readbyqxmd.com/read/28578901/pharmacological-treatments-and-risk-of-readmission-to-hospital-for-unipolar-depression-in-finland-a-nationwide-cohort-study
#15
Jari Tiihonen, Antti Tanskanen, Fabian Hoti, Pia Vattulainen, Heidi Taipale, Juha Mehtälä, Markku Lähteenvuo
BACKGROUND: Little is known about the comparative effectiveness of long-term pharmacological treatments for severe unipolar depression. We aimed to study the effectiveness of pharmacological treatments in relapse prevention in a nationwide cohort of patients who had been admitted to hospital at least once as a result of unipolar depression. METHODS: Our nationwide cohort study investigated the risk of readmission to hospital in 1996-2012 in all patients in Finland who had been admitted to hospital at least once for unipolar depression (without a diagnosis of schizophrenia or bipolar disorder) in Finland between Jan 1, 1987, and Dec 31, 2012...
June 1, 2017: Lancet Psychiatry
https://www.readbyqxmd.com/read/28576914/do-not-treat-the-numbers-lithium-toxicity
#16
Peter Foulser, Yasmin Abbasi, Anand Mathilakath, Ramin Nilforooshan
We describe the case of a 62-year-old man with a history of bipolar disorder, previously stable on lithium for over 20 years, who presented with a manic relapse and signs of lithium toxicity in the form of a coarse tremor. Serum lithium levels were in the normal range, and the patient had stage 3 chronic kidney disease. He was admitted for treatment under Section 2 of the Mental Health Act, and after stopping lithium was started on olanzapine. Signs of lithium toxicity improved after withdrawal of lithium. This case highlights the need to treat normal serum lithium levels with caution in patients showing signs of clinical lithium toxicity...
June 2, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28545329/psychotropic-drug-use-before-during-and-after-pregnancy-a-population-based-study-in-a-canadian-cohort-2001-2013
#17
Christine Leong, Colette Raymond, Dan Château, Matthew Dahl, Silvia Alessi-Severini, Jamie Falk, Shawn Bugden, Alan Katz
OBJECTIVE: To describe the extent of increase in use and the rate of continuation versus discontinuation of psychotropic agents before, during, and after pregnancy. METHODS: Rates of psychotropic use (antidepressants, anxiolytic/sedative-hypnotics, antiepileptics, antipsychotics, lithium, stimulants) among women with a hospital-recorded pregnancy outcome were assessed using databases at the Manitoba Centre for Health Policy. Rate of use was defined as ≥1 prescription over the total number of pregnancies in the 3-12 months before pregnancy, 0-3 months before pregnancy, during pregnancy, or 3 months after pregnancy...
August 2017: Canadian Journal of Psychiatry. Revue Canadienne de Psychiatrie
https://www.readbyqxmd.com/read/28539734/honey-and-health-a-review-of-recent-clinical-research
#18
REVIEW
Saeed Samarghandian, Tahereh Farkhondeh, Fariborz Samini
Honey is one of the most appreciated and valued natural products introduced to humankind since ancient times. Honey is used not only as a nutritional product but also in health described in traditional medicine and as an alternative treatment for clinical conditions ranging from wound healing to cancer treatment. The aim of this review is to emphasize the ability of honey and its multitude in medicinal aspects. Traditionally, honey is used in the treatment of eye diseases, bronchial asthma, throat infections, tuberculosis, thirst, hiccups, fatigue, dizziness, hepatitis, constipation, worm infestation, piles, eczema, healing of ulcers, and wounds and used as a nutritious supplement...
April 2017: Pharmacognosy Research
https://www.readbyqxmd.com/read/28494390/bipolar-patients-treated-with-long-acting-injectable-risperidone-in-taiwan-a-1-year-mirror-image-study-using-a-national-claims-database
#19
Ming H Hsieh, Po-Ya Chuang, Chi-Shin Wu, Ching-Jui Chang, Pei-Fang Chung, Chao-Hsiun Tang
OBJECTIVE: Bipolar disorder (BD) is burdensome for patients and healthcare systems. This study evaluated changes in concomitant medication patterns, healthcare utilization, and costs after the initiation of risperidone long-acting injection (RLAI) treatment among BD patients. METHOD: 287 BD patients receiving regular RLAI treatment for 1 year were identified from the Taiwan National Health Insurance Research database during 2007-2012. The bootstrapping procedure was performed to create 1000 samples to generate normally distributed data...
May 3, 2017: Journal of Affective Disorders
https://www.readbyqxmd.com/read/28492454/use-of-lithium-in-severe-acute-manic-episodes-retrospective-prescription-practice-from-a-tertiary-inpatient-unit
#20
Armağan Özdemir, Cana Aksoy Poyraz, Burç Ç Poyraz, Nazife G Usta Sağlam, Semra Enginkaya, Nesrin Tomruk
OBJECTIVE: A retrospective chart review was performed to investigate the common preferences of clinicians for the pharmacological treatment of acute manic episodes, with particular regard to lithium use, and to assess the adherence of clinical practice to established guidelines. METHODS: Cases of manic episodes in patients admitted to Bakirköy Mazhar Osman Mental Health and Neurological Diseases Education and Research Hospital were retrospectively reviewed. Length of stay, medication data, serum levels, and adverse effects were evaluated for patients who received lithium therapy (N=98)...
May 2017: Journal of Psychiatric Practice
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