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https://www.readbyqxmd.com/read/29713970/trends-of-metals-enrichment-in-deposited-particulate-matter-at-semi-arid-area-of-iran
#1
Reza Fouladi Fard, Kazem Naddafi, Mohammad Sadegh Hassanvand, Mohammad Khazaei, Farah Rahmani
The presence and enrichment of heavy metals in dust depositions have been recognized as an emerging environmental health issues in the urban and industrial areas. In this study, the deposition of some metals was found in Qom, a city located in a semi-desert area in Iran that is surrounded by industrial areas. Dust deposition samples were collected using five sampling stations during a year. Dust samples were digested applying acidic condition and then, the metal content was analyzed using inductively coupled plasma technology (ICP-OES)...
April 30, 2018: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/29685207/psychiatric-benefits-of-lithium-in-water-supplies-may-be-due-to-protection-from-the-neurotoxicity-of-lead-exposure
#2
Eric E Brown, Philip Gerretsen, Bruce Pollock, Ariel Graff-Guerrero
INTRODUCTION: Lithium is a medication used to treat bipolar disorder and may also prevent cognitive decline and suicide. Lithium is also found naturally, in levels well below clinical doses, in drinking water worldwide, and levels have been inversely associated with rates of psychiatric disorders. Lead (Pb) is another element in the environment but is a toxin of public health concern. Negative effects of chronic lead exposure and possible benefits of environmental lithium exposure appear complementary...
June 2018: Medical Hypotheses
https://www.readbyqxmd.com/read/29644348/degradation-of-thin-film-lithium-batteries-characterised-by-improved-potentiometric-measurement-of-entropy-change
#3
Xiao-Feng Zhang, Yan Zhao, Hong-Yan Liu, Teng Zhang, Wei-Ming Liu, Mu Chen, Yatish Patel, Gregory J Offer, Yue Yan
The degradation phenomena of thin-film solid state batteries caused by cycling at a high cut-off voltage and different temperatures were studied using an improved potentiometric measurement of entropy change combined with electrochemical impedance analysis and incremental capacity analysis. Entropy profiling is demonstrated as a viable non-destructive technique for solid state batteries that is sensitive to structural changes in electrodes during galvanostatic cycling, and is complementary to other techniques for studying degradation...
April 12, 2018: Physical Chemistry Chemical Physics: PCCP
https://www.readbyqxmd.com/read/29552933/is-lithium-monitoring-nice-lithium-monitoring-in-a-uk-secondary-care-setting
#4
Viktoriya L Nikolova, Keerati Pattanaseri, Diego Hidalgo-Mazzei, David Taylor, Allan H Young
BACKGROUND: Lithium is widely used for the treatment of bipolar disorder. Owing to its narrow therapeutic index and side-effect profile, regular monitoring of serum levels, renal and thyroid function has been recommended by all major guidelines on lithium use. OBJECTIVES: We investigated whether lithium monitoring during maintenance phase treatment in clinical practice meets the latest recommendation by the National Institute for Health and Clinical excellence (i...
April 2018: Journal of Psychopharmacology
https://www.readbyqxmd.com/read/29550861/respiratory-hazard-of-li-ion-battery-components-elective-toxicity-of-lithium-cobalt-oxide-licoo-2-particles-in-a-mouse-bioassay
#5
Violaine Sironval, Laurence Reylandt, Perrine Chaurand, Saloua Ibouraadaten, Mihaly Palmai-Pallag, Yousof Yakoub, Bernard Ucakar, Jérôme Rose, Claude Poleunis, Rita Vanbever, Etienne Marbaix, Dominique Lison, Sybille van den Brule
Rechargeable Li-ion batteries (LIB) are increasingly produced and used worldwide. LIB electrodes are made of micrometric and low solubility particles, consisting of toxicologically relevant elements. The health hazard of these materials is not known. Here, we investigated the respiratory hazard of three leading LIB components (LiFePO4 or LFP, Li4 Ti5 O12 or LTO, and LiCoO2 or LCO) and their mechanisms of action. Particles were characterized physico-chemically and elemental bioaccessibility was documented. Lung inflammation and fibrotic responses, as well as particle persistence and ion bioavailability, were assessed in mice after aspiration of LIB particles (0...
March 17, 2018: Archives of Toxicology
https://www.readbyqxmd.com/read/29540132/royal-australian-and-new-zealand-college-of-psychiatrists-clinical-practice-guidelines-for-mood-disorders-bipolar-disorder-summary
#6
Gin S Malhi, Tim Outhred, Grace Morris, Philip M Boyce, Richard Bryant, Paul B Fitzgerald, Malcolm J Hopwood, Bill Lyndon, Roger Mulder, Greg Murray, Richard J Porter, Ajeet B Singh, Kristina Fritz
In December 2015, the Royal Australian and New Zealand College of Psychiatrists published a comprehensive set of mood disorder clinical practice guidelines for psychiatrists, psychologists and mental health professionals. This guideline summary, directed broadly at primary care physicians, is an abridged version that focuses on bipolar disorder. It is intended as an aid to the management of this complex disorder for primary care physicians working in collaboration with psychiatrists to implement successful long term management...
March 19, 2018: Medical Journal of Australia
https://www.readbyqxmd.com/read/29518765/from-treating-childhood-malnutrition-to-public-health-nutrition
#7
W Philip T James
BACKGROUND: This analysis sets out an overview of an IUNS presentation of a European clinician's assessment of the challenges of coping with immediate critical clinical problems and how to use metabolic and a mechanistic understanding of disease when developing nutritional policies. SUMMARY: Critically ill malnourished children prove very sensitive to both mineral and general nutritional overload, but after careful metabolic control they can cope with a high-quality, energy-rich diet provided their initial lactase deficiency and intestinal atrophy are taken into account...
2018: Annals of Nutrition & Metabolism
https://www.readbyqxmd.com/read/29517996/from-the-psychiatrist-s-couch-to-induced-pluripotent-stem-cells-bipolar-disease-in-a-dish
#8
REVIEW
Anke Hoffmann, Vincenza Sportelli, Michael Ziller, Dietmar Spengler
Bipolar disease (BD) is one of the major public health burdens worldwide and more people are affected every year. Comprehensive genetic studies have associated thousands of single nucleotide polymorphisms (SNPs) with BD risk; yet, very little is known about their functional roles. Induced pluripotent stem cells (iPSCs) are powerful tools for investigating the relationship between genotype and phenotype in disease-relevant tissues and cell types. Neural cells generated from BD-specific iPSCs are thought to capture associated genetic risk factors, known and unknown, and to allow the analysis of their effects on cellular and molecular phenotypes...
March 8, 2018: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/29490359/real-world-effectiveness-of-pharmacologic-treatments-for-the-prevention-of-rehospitalization-in-a-finnish-nationwide-cohort-of-patients-with-bipolar-disorder
#9
Markku Lähteenvuo, Antti Tanskanen, Heidi Taipale, Fabian Hoti, Pia Vattulainen, Eduard Vieta, Jari Tiihonen
Importance: Mood stabilizers and antipsychotics are the main maintenance treatments for bipolar disorder. Lithium is considered to be the most effective mood stabilizer, but very little is known about overall health outcomes associated with specific treatments and the comparative long-term effectiveness of specific psychotropics or routes of administration in the prevention of rehospitalizations. Objective: To study the comparative effectiveness of pharmacologic treatments in the prevention of rehospitalization in a nationwide cohort of patients with bipolar disorder...
April 1, 2018: JAMA Psychiatry
https://www.readbyqxmd.com/read/29486442/reutilization-of-the-expired-tetracycline-for-lithium-ion-battery-anode
#10
Hongying Hou, Zhipeng Dai, Xianxi Liu, Yuan Yao, Qishu Liao, Chengyi Yu, Dongdong Li
Waste antibiotics into the natural environment are the large challenges to the environmental protection and the human health, and the unreasonable disposal of the expired antibiotics is a major pollution source. Herein, to achieve the innocent treatment and the resource recovery, the expired tetracycline was tried to be reutilized as the electrode active material in lithium ion battery (LIB) for the first time. The micro-structure and element component of the expired tetracycline were characterized by scanning electron microscope (SEM), energy dispersive X-ray spectroscopy (EDX), X-ray photoelectron spectroscopy (XPS) and Fourier transform infrared spectroscopy (FTIR)...
July 15, 2018: Science of the Total Environment
https://www.readbyqxmd.com/read/29484113/the-prevention-of-chemotherapy-induced-peripheral-neuropathy-by-concurrent-treatment-with-drugs-used-for-bipolar-disease-a-retrospective-chart-analysis-in-human-cancer-patients
#11
Roxanne J Wadia, Marilyn Stolar, Clarice Grens, Barbara E Ehrlich, Herta H Chao
Peripheral neuropathy is a major adverse effect in the use of chemotherapeutic drugs. In nearly 50% of patients, chemotherapy induced peripheral neuropathy (CIPN) has been reported as irreversible. With increasing numbers of patients surviving treatment as well as increasing duration of survival after treatment, reducing the side effects of chemotherapy and improving the quality of life has become a major focus of cancer survivorship. Multiple classes of chemotherapeutic drugs including taxanes, platinum agents and vinka alkaloids list peripheral neuropathy as the main dose-limiting side effect of treatment...
January 26, 2018: Oncotarget
https://www.readbyqxmd.com/read/29481993/long-term-use-of-valproic-acid-and-the-prevalence-of-cancers-in-bipolar-disorder-patients-in-a-taiwanese-population-an-association-analysis-using-the-national-health-insurance-research-database-nhird
#12
Cheng Chia Lin, Tsung-Cheng Hsieh, Lawrence Shih-Hsin Wu
BACKGROUND: Epigenetic events play a major role in the carcinogenesis of many cancers. A retrospective cohort study had been performed to evaluate the effects of exposure to the anticonvulsant agent valproic acid (VPA), a histone deacetylase inhibitor, on the risk of developing cancers. METHODS: The study was based on the 1998 through 2009 National Health Insurance Research Database (NHIRD), provided by the Taiwan National Health Research Institute. Patients with a diagnosis of bipolar disorder (ICD-9-CM codes 296...
May 2018: Journal of Affective Disorders
https://www.readbyqxmd.com/read/29471411/mechanisms-underpinning-the-polypharmacy-effects-of-medications-in-psychiatry
#13
Chiara C Bortolasci, Briana Spolding, Edward Callaly, Sheree Martin, Bruna Panizzutti, Srisaiyini Kidnapillai, Timothy Connor, Kyoko Hasebe, Mohammadreza Mohebbi, Olivia M Dean, Sean L McGee, Seetal Dodd, Laura Gray, Michael Berk, Ken Walder
Background: Bipolar disorder (BD) is a mental health condition with progressive social and cognitive function disturbances. Most patients' treatments are based on polypharmacy, but with no biological basis and little is known of the drugs' interactions. The aim of this study was to analyse the effects of lithium, valproate, quetiapine and lamotrigine, and the interactions between them, on markers of inflammation, bioenergetics, mitochondrial function and oxidative stress in neuron-like cells (NT2) and microglial cells...
February 19, 2018: International Journal of Neuropsychopharmacology
https://www.readbyqxmd.com/read/29463875/proliferation-and-apoptosis-of-t-lymphocytes-in-patients-with-bipolar-disorder
#14
Krzysztof Pietruczuk, Katarzyna A Lisowska, Karol Grabowski, Jerzy Landowski, Jacek M Witkowski
The aim of the study was to evaluate proliferation capacity and susceptibility to apoptosis of T lymphocytes of patients with bipolar disorder (BD) and to investigate in vitro influence of two standard mood stabilizers: lithium and valproic acid on these parameters using flow cytometry. Our results show that T lymphocytes of BD patients, especially those treated with lithium, have reduced proliferation capacity compared to healthy people. In vitro studies showed that valproic acid reduces the number of cell divisions and percentages of proliferating cells regardless of health status but mainly in very high dose, while lithium has no significant influence on proliferation capacity of patients' T lymphocytes...
February 20, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29436699/-bipolar-disorder-and-alcohol-use-disorder-practical-recommendations-for-treatment-based-on-a-literature-review
#15
A T Spijker, J van Zaane, M A Koenders, R Hoekstra, R W Kupka
A fairly large proportion (25-50%) of patients with bipolar disorder (bd) also suffer from comorbid alcohol use disorder (aud). However, little is known how this type of morbidity should be treated. It is also unclear whether the current guidelines on bd have been influenced by aud.<br/> AIM: To provide an overview of recent literature concerning the diagnosis and treatment of comorbid bd and aud.<br/> METHOD: We systematically reviewed studies that have addressed three treatment options for this group of patients: pharmaco-therapy, psychological interventions and self-management techniques...
2018: Tijdschrift Voor Psychiatrie
https://www.readbyqxmd.com/read/29425063/psychotropic-medication-patterns-for-american-indian-children-in-foster-care
#16
David Glesener, Gwendolyn Anderson, Xuan Li, Jacob Brown, James Amell, Ronald Regal, Donald Ferguson
OBJECTIVE: This study assesses the effects of race, age, sex, and time spent in foster care on rates of psychotropic medication use for children in foster care in 2012. METHODS: Using existing electronic records through county Social Service and Minnesota Medical Assistance databases, 626 children were identified using the inclusion criteria of having been in foster care for at least 30 days during 2012 in St. Louis County, Minnesota. All prescriptions for dispensed psychotropic medications were identified into the following classes: antidepressants, attention-deficit/hyperactivity disorder (ADHD) medications, antipsychotics, alpha-agonists, and other (including anticonvulsants/mood stabilizers, lithium, benzodiazepines, and sedative hypnotics)...
April 2018: Journal of Child and Adolescent Psychopharmacology
https://www.readbyqxmd.com/read/29383410/-pharmacogenetics-in-psychiatry-state-of-the-art
#17
REVIEW
D J Müller, E J Brandl, F Degenhardt, K Domschke, H Grabe, O Gruber, J Hebebrand, W Maier, A Menke, M Riemenschneider, M Rietschel, D Rujescu, T G Schulze, L Tebartz van Elst, O Tüscher, J Deckert
In this article, the current literature on pharmacogenetics of antidepressants, antipsychotics and lithium are summarized by the section of Neurobiology and Genetics of the German Society of Psychiatry, Psychotherapy and Neurology (DGPPN). The publications of international expert groups and regulatory authorities are reviewed and discussed. In Germany, a statement on pharmacogenetics was also made by the gene diagnostics committee of the Ministry of Health. The DGPPN supports two recommendations: 1) to perform CYP2D6 genetic testing prior to prescription of tricyclic antidepressants and 2) to determine the HLA-B*1502 genotype in patients of Asian origin before using carbamazepine...
March 2018: Der Nervenarzt
https://www.readbyqxmd.com/read/29366798/organic-reductants-based-leaching-a-sustainable-process-for-the-recovery-of-valuable-metals-from-spent-lithium-ion-batteries
#18
Xiangping Chen, Chunxiu Guo, Hongrui Ma, Jiazhu Li, Tao Zhou, Ling Cao, Duozhi Kang
It is significant to recover metal values from spent lithium ion batteries (LIBs) for the alleviation or prevention of potential risks towards environmental pollution and public health, as well as for the conservation of valuable metals. Herein a hydrometallurgical process was proposed to explore the possibility for the leaching of different metals from waste cathodic materials (LiCoO2 ) of spent LIBs using organics as reductant in sulfuric acid medium. According to the leaching results, about 98% Co and 96% Li can be leached under the optimal experimental conditions of reaction temperature - 95 °C, reaction time - 120 min, reductive agent dosage - 0...
January 20, 2018: Waste Management
https://www.readbyqxmd.com/read/29330449/lithium-chloride-effectively-kills-the-honey-bee-parasite-varroa-destructor-by-a-systemic-mode-of-action
#19
Bettina Ziegelmann, Elisabeth Abele, Stefan Hannus, Michaela Beitzinger, Stefan Berg, Peter Rosenkranz
Honey bees are increasingly important in the pollination of crops and wild plants. Recent reports of the weakening and periodical high losses of managed honey bee colonies have alarmed beekeeper, farmers and scientists. Infestations with the ectoparasitic mite Varroa destructor in combination with its associated viruses have been identified as a crucial driver of these health problems. Although yearly treatments are required to prevent collapses of honey bee colonies, the number of effective acaricides is small and no new active compounds have been registered in the past 25 years...
January 12, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29311666/a-study-of-the-influence-of-measurement-timescale-on-internal-resistance-characterisation-methodologies-for-lithium-ion-cells
#20
Anup Barai, Kotub Uddin, W D Widanage, Andrew McGordon, Paul Jennings
The power capability of a lithium ion battery is governed by its resistance, which changes with battery state such as temperature, state of charge, and state of health. Characterizing resistance, therefore, is integral in defining battery operational boundaries, estimating its performance and tracking its state of health. There are many techniques that have been employed for estimating the resistance of a battery, these include: using DC pulse current signals such as pulse power tests or Hybrid Pulse Power Characterization (HPPC) tests; using AC current signals, i...
January 8, 2018: Scientific Reports
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