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https://www.readbyqxmd.com/read/28209497/a-multicenter-assessment-of-the-ability-of-preoperative-computed-tomography-scan-and-ca-125-to-predict-gross-residual-disease-at-primary-debulking-for-advanced-epithelial-ovarian-cancer
#1
Rudy S Suidan, Pedro T Ramirez, Debra M Sarasohn, Jerrold B Teitcher, Revathy B Iyer, Qin Zhou, Alexia Iasonos, John Denesopolis, Oliver Zivanovic, Kara C Long Roche, Yukio Sonoda, Robert L Coleman, Nadeem R Abu-Rustum, Hedvig Hricak, Dennis S Chi
OBJECTIVE: To assess the ability of preoperative computed tomography scan and CA-125 to predict gross residual disease (RD) at primary cytoreduction in advanced ovarian cancer. METHODS: A prospective, non-randomized, multicenter trial of patients who underwent primary debulking for stage III-IV epithelial ovarian cancer previously identified 9 criteria associated with suboptimal (>1cm residual) cytoreduction. This is a secondary post-hoc analysis looking at the ability to predict any RD...
February 13, 2017: Gynecologic Oncology
https://www.readbyqxmd.com/read/28205454/graft-complexity-related-outcomes-of-fenestrated-endografting-for-abdominal-aortic-aneurysms
#2
Kyriakos Oikonomou, Piotr Kasprzak, Wilma Schierling, Reinhard Kopp, Karin Pfister
PURPOSE: To report the outcomes of fenestrated endovascular aneurysm repair (FEVAR) and compare early and midterm results in relation to stent-graft complexity. METHODS: Between August 2006 and December 2014, 141 consecutive patients (mean age 72±7.6 years, range 50-89; 120 men) were treated electively with FEVAR for short-neck, juxtarenal, or suprarenal aortic aneurysms. Forty-five patients treated with stent-grafts featuring renal-only fenestrations were assigned to group A, while 96 patients receiving additional fenestrations for the superior mesenteric and/or celiac arteries were assigned to group B...
February 1, 2017: Journal of Endovascular Therapy
https://www.readbyqxmd.com/read/28205450/push-up-technique-and-anatomical-deployment-with-the-endurant-stent-graft-system-for-severely-angulated-aneurysm-necks
#3
Shizuyuki Dohi, Yasutaka Yokoyama, Taira Yamamoto, Kenji Kuwaki, Akifusa Hariya, Kan Kajimoto, Hironobu Yamaoka, Akie Shimada, Ryo Tsuruta, Atsushi Amano
PURPOSE: To describe a technique suitable for treating severely angulated (>75°) necks during endovascular aneurysm repair using the Endurant stent-graft. TECHNIQUE: In the push-up technique, the suprarenal stent is released early to fix the proximal stent-graft in place so that each stent in the neck can be deployed individually without displacing the device upward. It is important to push the delivery system up after each stent deployment to allow the fabric between the stents to fold up circumferentially...
February 1, 2017: Journal of Endovascular Therapy
https://www.readbyqxmd.com/read/28167283/pre-operative-renal-artery-embolization-and-suprarenal-ivc-filter-placement-for-prevention-of-fat-embolization-in-renal-angiomyolipoma-with-venous-extension
#4
Joshua Cornman-Homonoff, David Li, Marc Schiffman
Though generally considered benign, angiomyolipomas can invade through the renal vein into the inferior vena cava, putting patients at risk of catastrophic pulmonary fat embolization. Venous invasion is thus an indication for surgical resection but is thought to increase the risk of adverse operative outcomes including intraoperative hemorrhage and embolization of fat and/or tumor thrombus. We report a novel approach to mitigating these complications illustrated in the case of a 43-year-old woman with IVC-invasive renal AML who underwent successful radical nephrectomy after concurrent pre-operative renal artery embolization and placement of a retrievable suprarenal IVC filter...
January 26, 2017: Clinical Imaging
https://www.readbyqxmd.com/read/28139105/-establishment-of-a-preclinical-neuroblastoma-model-in-immunocompetent-mice
#5
A L Luis, M Espinoza, L Franco, A González-Murillo, G J Melen, J C Ollero Fresno, L Madero, M Ramírez
AIM: To develop a NB animal model which makes possible studies related to tumor immunity. MATERIALS AND METHODS: Two types of NB cells were used. Cell line 36769 was derived from TH-MYCN+ mouse in which overexpression of the MYCN gene is governed by rat tyrosine hydroxylase promotor. Cell line 4040 was derived from TH-MYCN/ALK mice, which in addition express an activating mutation of ALK gene. For each cell type, 1x10(6) neurospheres were implanted in 129/SVJ mice (with the same genetic background as donors, n=8), via orthotopic injection in the left suprarenal gland by intraperitoneal approach, through a transverse supraumbilical laparotomy...
April 10, 2016: Cirugía Pediátrica: Organo Oficial de la Sociedad Española de Cirugía Pediátrica
https://www.readbyqxmd.com/read/28139103/-intestinal-duplication-a-single-experiencie-center
#6
M A Cárdenas Elias, F Vázaquez Rueda, J E Betancourth-Alvarenga, M Centeno Haro, F J Murcia Pascual, R M Paredes Esteban
PURPOUSE: Intestinal duplications (DI) are rare congenital anomalies (1/10.000 new born). We analyze the clinical characteristics, management and treatment of intestinal duplications in our center. MATERIALS AND METHODS: We perform a retrospectively descriptive analysis review by the DI confirmed by histological studies since 1993-2014 in our center. The variables analyzed are: age, sex, clinical presentation, localization, anatomical type, associated diseases, heterotopic tissue, treatment and complications...
April 10, 2016: Cirugía Pediátrica: Organo Oficial de la Sociedad Española de Cirugía Pediátrica
https://www.readbyqxmd.com/read/28128541/fenestrated-and-chimney-endovascular-aneurysm-repair-versus-open-surgery-for-complex-abdominal-aortic-aneurysms
#7
Vicente A Sala-Almonacil, José M Zaragozá-García, Mauricio Ramírez-Montoya, Vicente Molina-Nácher, Inmaculada Martínez-Perelló, Francisco J Gómez-Palonés
BACKGROUND: Many patients with complex abdominal aortic aneurysms are unfit for open repair. New endovascular technologies and bailout techniques are being used for managing those complex anatomies. The purpose of this study is to compare the results obtained with advanced endovascular aneurysm repair techniques (fenestrated and chimney endografts) to those obtained with open repair for the treatment of complex abdominal aortic aneurysms not anatomically suitable for standard endovascular exclusion (infrarenal neck <10 mm, juxtarenal, suprarenal and Crawford's type IV thoracoabdominal aneurysms)...
January 27, 2017: Journal of Cardiovascular Surgery
https://www.readbyqxmd.com/read/28102772/an-extensive-suprarenal-inferior-vena-cava-thrombosis-successfully-treated-with-catheter-directed-thrombolysis-in-a-postpartum-14-year-old-girl
#8
Roxana Cristina Rimbas, Simona Ionela Călin, Horatiu Ionescu, Bogdan Dorobat, Dragos Vinereanu, Mircea Cinteza
We report a case of extensive early postpartum acute suprarenal inferior vena cava thrombosis in a 14-year-old girl. Management included catheter-directed-thrombolysis, aiming to save renal function and prevent fatal pulmonary embolism. Treatment decisions were mostly based on adult guidelines, as guidelines for the paediatric population are not yet available.
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January 19, 2017: VASA. Zeitschrift Für Gefässkrankheiten
https://www.readbyqxmd.com/read/28076290/tailored-interactive-sequences-for-continuous-mr-image-guided-freehand-biopsies-of-different-organs-in-an-open-system-at-1-0-tesla-t-initial-experience
#9
Florian Streitparth, Christian Althoff, Martin Jonczyk, Felix Guettler, Martin Maurer, Hendrik Rathke, Keno Moritz Sponheuer, Bernd Hamm, Ulf K Teichgräber, Maximilian de Bucourt
OBJECTIVES: To assess the feasibility, image quality, and accuracy of freehand biopsies of liver, bone, muscle, vertebral disc, soft tissue, and other lesions using balanced steady-state free precession (SSFP, balanced fast field echo: bFFE), spoiled and nonspoiled gradient echo (FFE), and turbo spin echo (TSE) sequences for interactive continuous navigation in an open magnetic resonance imaging (MRI) system at 1.0 tesla (T). METHODS: Twenty-six MR-guided biopsies (five liver, five bone, four muscle, four vertebral disc, one lung, one kidney, one suprarenal gland, and five soft or other tissue) were performed in 23 patients in a 1...
January 11, 2017: Biomedizinische Technik. Biomedical Engineering
https://www.readbyqxmd.com/read/28073666/standard-endovascular-aneurysm-repair-in-patients-with-wide-infrarenal-aneurysm-necks-is-associated-with-increased-risk-of-adverse-events
#10
Nelson F G Oliveira, Frederico M Bastos Gonçalves, Marie Josee Van Rijn, Quirina de Ruiter, Sanne Hoeks, Jean-Paul P M de Vries, Joost A van Herwaarden, Hence J M Verhagen
OBJECTIVE: Endovascular aneurysm repair (EVAR) has progressively expanded to treat more challenging anatomies. Although EVAR in patients with wide infrarenal necks has been reported with acceptable results, there is still controversy regarding the longer-term outcomes. Our aim is to determine the impact of infrarenal neck diameter on midterm outcome following EVAR with a single endograft with suprarenal fixation. METHODS: A retrospective case-control study was designed using data from a prospective multicenter database...
January 7, 2017: Journal of Vascular Surgery
https://www.readbyqxmd.com/read/28011005/the-enduring-patency-of-primary-inferior-vena-cava-repair
#11
Neel A Mansukhani, George E Havelka, Irene B Helenowski, Heron E Rodriguez, Andrew W Hoel, Mark K Eskandari
BACKGROUND: Inferior vena cava repair after planned and unplanned venotomy is performed by either interposition bypass, patch venopasty, or lateral venorrhaphy and primary repair. Primary repair of the inferior vena cava avoids the use of foreign material and allows an all-autologous repair in an expeditious fashion. The purpose of this study was to demonstrate the utility of inferior vena cava repair, determine the degree of inferior vena cava stenosis, and examine clinical outcomes after primary repair...
December 20, 2016: Surgery
https://www.readbyqxmd.com/read/28008986/inhibition-of-farnesyl-pyrophosphate-synthase-improves-pressure-overload-induced-chronic-cardiac-remodeling
#12
Chen-Ze Zhao, Xu-Ming Zhao, Jian Yang, Yun Mou, Bin Chen, Huan-Dong Wu, Dong-Pu Dai, Jie Ding, Shen-Jiang Hu
Farnesyl pyrophosphate synthase (FPPS) is a key enzyme in the mevalonate pathway. In our previous studies, we find that inhibition of FPPS attenuates angiotensin II-induced cardiac hypertrophy and fibrosis by suppressing RhoA while FPPS and Ras are up-regulated in pressure overload rats. In this study, we evaluate the effects and mechanisms of FPPS inhibition in pressure overload mice. Male FPPS-small interfering RNA (SiRNA) transgenic (Tg) mice and non-transgenic littermate control (NLC) were randomly divided into suprarenal abdominal aortic constriction (AAC) group and sham operation group...
December 23, 2016: Scientific Reports
https://www.readbyqxmd.com/read/28006695/role-of-atrial-endothelial-cells-in-the-development-of-atrial-fibrosis-and-fibrillation-in-response-to-pressure-overload
#13
Osamu Kume, Yasushi Teshima, Ichitaro Abe, Yuki Ikebe, Takahiro Oniki, Hidekazu Kondo, Shotaro Saito, Akira Fukui, Kunio Yufu, Masahiro Miura, Tatsuo Shimada, Naohiko Takahashi
BACKGROUND: Monocyte chemoattractant protein-1 (MCP-1)-mediated inflammatory mechanisms have been shown to play a crucial role in atrial fibrosis induced by pressure overload. In the present study, we investigated whether left atrial endothelial cells would quickly respond structurally and functionally to pressure overload to trigger atrial fibrosis and fibrillation. METHODS AND RESULTS: Six-week-old male Sprague-Dawley rats underwent suprarenal abdominal aortic constriction (AAC) or a sham operation...
December 15, 2016: Cardiovascular Pathology: the Official Journal of the Society for Cardiovascular Pathology
https://www.readbyqxmd.com/read/27987609/endovascular-management-of-chronic-total-occlusions-of-the-inferior-vena-cava-and-iliac-veins
#14
Erin H Murphy, Blake Johns, Elliot Varney, Seshadri Raju
OBJECTIVE: Percutaneous recanalization and stenting is currently the standard of care for symptomatic chronic total occlusions (CTOs) of the iliofemoral veins. CTO lesions involving the inferior vena cava (IVC) present a more complex patient subset. In this series we describe our single-center experience with endovascular recanalization of symptomatic occlusions of the IVC. METHODS: Patients were evaluated with duplex ultrasound imaging, venous function tests, and venography before intervention...
January 2017: Journal of Vascular Surgery. Venous and Lymphatic Disorders
https://www.readbyqxmd.com/read/27986483/contemporary-open-repair-of-ruptured-abdominal-aortic-aneurysms
#15
Jeffrey J Siracuse, Brianna M Krafcik, Alik Farber, Jeffrey A Kalish, Andrew McChesney, Denis Rybin, Gheorghe Doros, Mohammad H Eslami
OBJECTIVE: Although endovascular repair of ruptured abdominal aortic aneurysms (rAAAs) is increasingly more prevalent and may yield better results, open repair of rAAAs is still commonly performed. Our goal was to assess the contemporary practice patterns and outcomes of open repair of rAAA. METHODS: The 2011-2014 American College of Surgeons National Surgical Quality Improvement Program targeted open AAA database was queried for all rAAAs. Patient characteristics, presentation, aneurysm details, and operative details were analyzed to identify factors that may affect outcome in this population of patients...
December 13, 2016: Journal of Vascular Surgery
https://www.readbyqxmd.com/read/27974495/a-systematic-review-of-proximal-neck-dilatation-after-endovascular-repair-for-abdominal-aortic-aneurysm
#16
George N Kouvelos, Kyriakos Oikonomou, George A Antoniou, Eric L G Verhoeven, Athanasios Katsargyris
PURPOSE: To provide an updated systematic literature review and summarize current evidence on proximal aortic neck dilatation (AND) after endovascular aneurysm repair (EVAR). METHODS: A review of the English-language medical literature from 1991 to 2015 was conducted using MEDLINE and EMBASE to identify studies reporting AND after EVAR. Studies considered for inclusion and full-text review fulfilled the following criteria: (1) reported AND after EVAR, (2) included at least 5 patients, and (3) provided data on AND quantification...
February 2017: Journal of Endovascular Therapy
https://www.readbyqxmd.com/read/27894713/abdominal-aortic-aneurysm-in-marfan-syndrome
#17
Tracy Hagerty, Patrick Geraghty, Alan C Braverman
OBJECTIVE: Marfan syndrome (MFS) leads to aortic root aneurysm, while descending thoracic aortic aneurysm (TAA) occurs less commonly. Abdominal aortic aneurysm (AAA) is rarely reported in MFS. Risk factors for AAA are poorly understood and there are no guidelines for AAA screening in MFS. We sought to characterize AAA among Marfan patients in our center. METHODS: The records of 12 adults with MFS and AAA disease were reviewed. Clinical features, imaging, operative reports, and outcomes were analyzed...
November 25, 2016: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/27890849/hybrid-treatment-of-a-suprarenal-aortic-aneurysm-with-an-infrarenal-aortobifemoral-surgical-graft-and-a-fenestrated-stent-graft
#18
Sebastian Nagel, Athanasios Katsargyris, Kyriakos Oikonomou, Eric L G Verhoeven
BACKGROUND: The aim of this study was to report a hybrid technique for the treatment of a suprarenal aortic aneurysm (SAA) in a patient with iliac occlusive disease. Initially, an infrarenal aortobifemoral surgical graft was implanted, followed by deployment of a fenestrated bifurcated stent graft at the suprarenal part of the aorta. METHODS: A 69-year-old man presented with a 51-mm saccular suprarenal aortic aneurysm and iliac occlusive disease with intermittent claudication...
November 24, 2016: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/27890835/acute-kidney-injury-after-open-repair-of-intact-abdominal-aortic-aneurysms
#19
REVIEW
Charles Dariane, Raphaël Coscas, Celia Boulitrop, Isabelle Javerliat, Eve Vilaine, Olivier Goeau-Brissonniere, Marc Coggia, Ziad A Massy
BACKGROUND: These last years, considerable attention has been given to renal issues following endovascular aortic repair but acute kidney injury (AKI) also remains one of the most frequent complications following open repair (OR). Since AKI definition has evolved, our aim was to review the etiology, incidence, classifications, and consequences of AKI after OR for intact abdominal aortic aneurysm (AAA). METHODS: A review of the English language literature published between 2004 and 2016 was conducted according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) criteria...
November 24, 2016: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/27890833/pulse-wave-analysis-after-treatment-of-abdominal-aortic-aneurysms-with-the-ovation-device
#20
Efstratios Georgakarakos, Christos Argyriou, George S Georgiadis, Miltos K Lazarides
BACKGROUND: Ovation aortic stent-graft system is a new device for the endovascular treatment of Abdominal Aortic Aneurysms achieving fixation via a 35-mm long, rigid anchored suprarenal stent and sealing stent at the infrarenal level by a means of a polymer-filling pair of inflatable O-rings, which cause narrowing of flow lumen and regional stenosis. Thus, concerns have been raised regarding hemodynamic consequences associated with this new design. Our preliminary report showed no significant increase of aortic pulse wave velocity (aPWV) immediately after implantation of the ovation in 3 patients...
November 25, 2016: Annals of Vascular Surgery
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