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https://www.readbyqxmd.com/read/29763980/arterial-stiffness-in-people-with-type-2-diabetes-and-obstructive-sleep-apnoea
#1
M Hvelplund Kristiansen, A M Banghøj, E Laugesen, L Tarnow
AIMS: To examine whether people with Type 2 diabetes with concurrent obstructive sleep apnoea have increased arterial stiffness as compared with people with Type 2 diabetes without obstructive sleep apnoea. METHODS: In a study with a case-control design, 40 people with Type 2 diabetes and treatment-naïve moderate to severe obstructive sleep apnoea (Apnoea-Hypopnoea Index ≥15) and a control group of 31 people with Type 2 diabetes without obstructive sleep apnoea (Apnoea-Hypopnoea Index <5) were examined...
May 15, 2018: Diabetic Medicine: a Journal of the British Diabetic Association
https://www.readbyqxmd.com/read/29687610/paravertebral-injection-of-botulinum-toxin-a-reduces-lumbar-vertebral-bone-quality
#2
Xuepeng Wang, Shengjie Wang, Peng Yan, Zhenyu Bian, Maoqiang Li, Changju Hou, Jiwei Tian, Liulong Zhu
Aging has been associated with decreases in muscle strength and bone quality. In older patients, paravertebral muscle atrophy tends to coincide with vertebral osteoporosis. The purpose of this study was to investigate the effects of a paravertebral injection of botulinum toxin-A (BTX) on paravertebral muscle atrophy and lumbar vertebral bone quality. Forty 16-week-old female SD rats were randomly divided into four groups: (1) a control group (CNT); (2) a resection of erector spinae muscles group (RESM); (3) a botulinum toxin-A group (BTX), treated with 5U BTX by local injection into the paravertebral muscles bilaterally; and (4) a positive control group (OVX), treated by bilateral ovariectomy...
April 24, 2018: Journal of Orthopaedic Research: Official Publication of the Orthopaedic Research Society
https://www.readbyqxmd.com/read/29425575/effect-of-a-patient-engagement-tool-on-positive-airway-pressure-adherence-analysis-of-a-german-healthcare-provider-database
#3
Holger Woehrle, Michael Arzt, Andrea Graml, Ingo Fietze, Peter Young, Helmut Teschler, Joachim H Ficker
OBJECTIVE/BACKGROUND: This study investigated the addition of a real-time feedback patient engagement tool on positive airway pressure (PAP) adherence when added to a proactive telemedicine strategy. PATIENTS/METHODS: Data from a German healthcare provider (ResMed Healthcare Germany) were retrospectively analyzed. Patients who first started PAP therapy between 1 September 2009 and 30 April 2014, and were managed using telemedicine (AirView™; proactive care) or telemedicine + patient engagement tool (AirView™ + myAir™; patient engagement) were eligible...
January 2018: Sleep Medicine
https://www.readbyqxmd.com/read/29228525/sleep-apnea-and-idiopathic-leg-edema-a-case-control-study
#4
Reza Shahmirzai, Mohammadreza Firouzifar
Idiopathic leg edema is subject to a lot of debates among physicians. Recently sleep apnea was stated to be the cause. We sought to investigate this matter in a sample of Iranian patients with idiopathic leg edema. In this case-control study, 110 patients were selected based on our inclusion/exclusion criteria and allocated to the case (with idiopathic edema, n=55) and control (without edema, n=55) groups. Sex, age, weight, height, and body mass index (BMI) of all subjects were recorded. We evaluated daytime somnolence of all patients using Epworth sleepiness scale and then calculated Apnea, hypopnea index (AHI) using ResMed ApneaLink and AHI≥15 were considered as sleep apnea...
October 2017: Acta Medica Iranica
https://www.readbyqxmd.com/read/28899539/can-the-analysis-of-built-in-software-of-cpap-devices-replace-polygraphy-in-children
#5
Sonia Khirani, Vincent Delord, Jorge Olmo Arroyo, Livio De Sanctis, Annick Frapin, Alessandro Amaddeo, Brigitte Fauroux
OBJECTIVES: Polysomnography (PSG) is the gold standard for the scoring of residual respiratory events during continuous positive airway pressure (CPAP). Studies comparing PSG scoring with automatic scoring by the built-in software of CPAP devices have reported acceptable agreements except for the hypopnea index (HI) in adult patients, but no study has yet been conducted in children. The aim of the present study was to compare the automatic scoring by CPAP device and manual scoring using the software tracings of the CPAP device integrating pulse oximetry (SpO2 ) with in-lab polygraphy (PG)...
September 2017: Sleep Medicine
https://www.readbyqxmd.com/read/28822017/validation-of-a-non-contact-screening-device-for-the-combination-of-sleep-disordered-breathing-and-periodic-limb-movements-in-sleep
#6
Gerhard Weinreich, Sarah Terjung, Yi Wang, Stefanie Werther, Alberto Zaffaroni, Helmut Teschler
PURPOSE: Recent studies found that the non-contact screening device SleepMinder (ResMed Sensor Technologies, Dublin, Ireland) detects sleep-disordered breathing (SDB) with high diagnostic accuracy in cohorts suspected of this disorder. However, it was reported that in patients with periodic limb movement in sleep (PLMS), this non-contact device overestimates the apnea-hypopnea index (AHI). We aimed to overcome this limitation by introducing the novel sleep disorder index (SDI) which is sum of the AHI and the period limb movement index (PLMI)...
March 2018: Sleep & Breathing, Schlaf & Atmung
https://www.readbyqxmd.com/read/28794858/monitoring-respiration-and-oxygen-saturation-in-patients-during-the-first-night-after-elective-bariatric-surgery-a-cohort-study
#7
Liselott Wickerts, Sune Forsberg, Frederic Bouvier, Jan Jakobsson
Background : Obstructive sleep apnoea and obese hypoventilation is not uncommon in patients with obesity. Residuals effect from surgery/anaesthesia and opioid analgesics may worsen respiration during the first nights after bariatric surgery. The aim of this observational study was to monitor respiration on the first postoperative night following elective bariatric surgery. Methods : This observational study aimed to determine the incidence and severity of hypo/apnoea in low risk obsess patients undergoing elective bariatric surgery in general anesthaesia...
2017: F1000Research
https://www.readbyqxmd.com/read/28753994/noncontact-sleep-study-by-multi-modal-sensor-fusion
#8
Ku-Young Chung, Kwangsub Song, Kangsoo Shin, Jinho Sohn, Seok Hyun Cho, Joon-Hyuk Chang
Polysomnography (PSG) is considered as the gold standard for determining sleep stages, but due to the obtrusiveness of its sensor attachments, sleep stage classification algorithms using noninvasive sensors have been developed throughout the years. However, the previous studies have not yet been proven reliable. In addition, most of the products are designed for healthy customers rather than for patients with sleep disorder. We present a novel approach to classify sleep stages via low cost and noncontact multi-modal sensor fusion, which extracts sleep-related vital signals from radar signals and a sound-based context-awareness technique...
July 21, 2017: Sensors
https://www.readbyqxmd.com/read/28706464/telemedicine-based-proactive-patient-management-during-positive-airway-pressure-therapy-impact-on-therapy-termination-rate
#9
Holger Woehrle, Joachim H Ficker, Andrea Graml, Ingo Fietze, Peter Young, Helmut Teschler, Michael Arzt
BACKGROUND: Adherence to positive airway pressure (PAP) therapy is essential for the benefits of therapy to be realised. Telemedicine-based strategies provide a new option for enhanced monitoring and intervention to promote adherence during PAP. This study investigated the impact of telemedicine-based proactive patient management on PAP therapy termination rates versus standard care. METHODS: Observational data were obtained from ResMed Germany Healthcare, a German homecare provider...
2017: Somnologie: Schlafforschung und Schlafmedizin, Somnology: Sleep Research and Sleep Medicine
https://www.readbyqxmd.com/read/28449886/a-novel-postal-based-approach-to-diagnosing-obstructive-sleep-apnoea-in-a-high-risk-population
#10
RANDOMIZED CONTROLLED TRIAL
Benjamin Prudon, Joan Hughes, Sophie West
OBJECTIVE: More than 50% of patients with diabetic macular oedema (DMO) have obstructive sleep apnoea (OSA), but the majority remain undiagnosed. We used a four-channel device (ApneaLink [AL], ResMed, UK) to establish a remote postal-based diagnostic service for patients with DMO. Here we describe our experience. METHODS: Patients with DMO were invited to participate. Interested patients returned a free-post reply slip to the study team, who posted an AL with pictorial and written instructions to them...
May 2017: Sleep Medicine
https://www.readbyqxmd.com/read/28205227/impact-of-obstructive-sleep-apnea-on-neurological-recovery-after-ischemic-stroke-a-prospective-study
#11
D Menon, S Sukumaran, R Varma, A Radhakrishnan
OBJECTIVES: The presence of obstructive sleep apnea (OSA) has been found to adversely affect the neurological recovery after acute ischemic stroke (AIS) in previous observational studies. However, in most of these studies, diagnosis of OSA was based on oximetry data alone, raising concern in the accuracy of diagnosis as well as estimation of severity. Purpose of our study was to determine the prevalence and severity of OSA (based on polysomnography and American Association of Sleep Medicine [AASM] criteria) in patients with AIS and to compare the post-stroke neurological and functional outcome, in those with and without OSA...
November 2017: Acta Neurologica Scandinavica
https://www.readbyqxmd.com/read/27975178/central-sleep-apnea-in-multiple-sclerosis-a-pilot-study
#12
Michael Lin, Arun V Krishnan, Danny J Eckert
PURPOSE: The purpose of the present study is to investigate sleep-disordered breathing and symptoms of sleepiness in a consecutive clinical cohort of multiple sclerosis (MS) patients. METHODS: Twenty-one (16 females) community-dwelling adults aged 18-75 years with MS and an Expanded Disability Status Scale score between 2 and 6 were recruited consecutively from an academic teaching hospital MS clinic. Participants performed a home sleep study (ResMed ApneaLink Plus) to objectively quantify sleep-disordered breathing...
September 2017: Sleep & Breathing, Schlaf & Atmung
https://www.readbyqxmd.com/read/27903350/-effect-of-lumbar-dorsal-muscle-injuries-on-lumbar-vertebral-bone-quality-of-rat
#13
X P Wang, S J Wang, P Yan, L L Zhu, M Q Li, Z Y Bian, J W Tian
Objective: To explored the effects of lumbar dorsal muscle damage on local lumbar vertebral bone quality. Methods: Thirty SD female rats, at age of 20 weeks, were randomly divided into three groups: control group, or say pseudo surgery group, an incision in the back were performed as CNT; bilateral erector spinal muscle group in which group bilateral lumbar erector spinal muscle were removed as RESM; castration group in which bilateral ovaries were resected as OVX.After three months, bone mineral density, microscopic CT and vertebral compression test were taken in lumbar vertebral (L4-6) in turn...
November 22, 2016: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://www.readbyqxmd.com/read/27648308/impact-of-a-new-nasal-pillows-mask-on-patients-acceptance-compliance-and-willingness-to-remain-on-cpap-therapy
#14
Alison Wimms, Sahisha Ketheeswaran, Claus Ziegenbein, Laura Jennings, Holger Woehrle
Aim. Continuous positive airway pressure (CPAP) masks are a key factor in patient compliance. This program assessed the performance of a new nasal pillows mask (NPM) on a variety of new and established obstructive sleep apnea (OSA) patients using CPAP therapy. Methods. Five programs were developed to assess the new NPM [AirFit P10, ResMed] on naïve patients; patients established on another NPM; patients using a nasal mask; patients with low CPAP compliance; and patients who wished to stop using CPAP therapy...
2016: Sleep Disorders
https://www.readbyqxmd.com/read/27592224/mechanisms-underlying-increased-mortality-risk-in-patients-with-heart-failure-and-reduced-ejection-fraction-randomly-assigned-to-adaptive-servoventilation-in-the-serve-hf-study-results-of-a-secondary-multistate-modelling-analysis
#15
RANDOMIZED CONTROLLED TRIAL
Christine Eulenburg, Karl Wegscheider, Holger Woehrle, Christiane Angermann, Marie-Pia d'Ortho, Erland Erdmann, Patrick Levy, Anita K Simonds, Virend K Somers, Faiez Zannad, Helmut Teschler, Martin R Cowie
BACKGROUND: A large randomised treatment trial (SERVE-HF) showed that treatment of central sleep apnoea with adaptive servoventilation in patients with heart failure and reduced ejection fraction (HFREF) increased mortality, although the analysis of the composite primary endpoint (time to first event of death from any cause, life-saving cardiovascular intervention, or unplanned hospital admission for worsening heart failure) was neutral. This secondary multistate modelling analysis of SERVE-HF data investigated associations between adaptive servoventilation and individual components of the primary endpoint to try to better understand the mechanisms underlying the observed increased mortality...
November 2016: Lancet Respiratory Medicine
https://www.readbyqxmd.com/read/27323697/effects-of-positive-end-expiratory-pressure-administration-during-non-invasive-ventilation-in-patients-affected-by-amyotrophic-lateral-sclerosis-a-randomized-crossover-study
#16
RANDOMIZED CONTROLLED TRIAL
Grazia Crescimanno, Francesca Greco, Salvo Arrisicato, Noemi Morana, Oreste Marrone
BACKGROUND AND OBJECTIVE: No studies have evaluated the impact of different settings of non-invasive ventilation (NIV) in patients affected by amyotrophic lateral sclerosis (ALS). We explored consequences of positive end-expiratory pressure (PEEP) application on effectiveness of ventilation, sleep architecture and heart rate variability (HRV) in patients with ALS naïve to ventilatory treatment. METHODS: In two consecutive nights, 25 patients received in random order 0 or 4 cm H2 0 of PEEP during nocturnal NIV administration (Idea Ultra ResMed) with the same level of total positive inspiratory pressure...
October 2016: Respirology: Official Journal of the Asian Pacific Society of Respirology
https://www.readbyqxmd.com/read/27043327/telemonitoring-of-cpap-therapy-may-save-nursing-time
#17
Ulla Anttalainen, Sari Melkko, Sirkka Hakko, Tarja Laitinen, Tarja Saaresranta
PURPOSE: Telemonitoring might enhance continuous positive airway pressure (CPAP) adherence and save nursing time at the commencement of CPAP therapy. We tested wireless telemonitoring (ResTraxx Online System®, ResMed) during the habituation phase of the CPAP therapy in obstructive sleep apnea syndrome (OSAS). METHODS: In total, 111 consecutive OSAS patients were enrolled. After CPAP titration, patients were followed with the telemonitoring (TM, N = 50) or the usual care (UC, N = 61)...
December 2016: Sleep & Breathing, Schlaf & Atmung
https://www.readbyqxmd.com/read/26780403/impact-of-different-nasal-masks-on-cpap-therapy-for-obstructive-sleep-apnea-a-randomized-comparative-trial
#18
Pierre-Charles Neuzeret, Laurent Morin
INTRODUCTION: Patient interface is important for the success of continuous positive airway pressure (CPAP), but few trials have examined the influence of mask choice on CPAP adherence. OBJECTIVES: To compare the impact of different nasal masks on CPAP in patients with newly-diagnosed obstructive sleep apnea (OSA). METHODS: OSA patients were randomized in a 2:3 ratio to receive CPAP via different first-line nasal masks: ResMed Mirage FX® (MFX) or control mask (Fisher & Paykel Zest(®) , HC407(®) or Philips EasyLife(®) )...
January 18, 2016: Clinical Respiratory Journal
https://www.readbyqxmd.com/read/26682790/prevalence-and-predictors-of-sleep-disordered-breathing-in-patients-with-stable-chronic-heart-failure-the-schlahf-registry
#19
RANDOMIZED CONTROLLED TRIAL
Michael Arzt, Holger Woehrle, Olaf Oldenburg, Andrea Graml, Anna Suling, Erland Erdmann, Helmut Teschler, Karl Wegscheider
OBJECTIVES: This prospective study investigated the prevalence of sleep-disordered breathing (SDB) and its predictors in patients with stable chronic heart failure (HF). BACKGROUND: SDB is increasingly recognized as being important in patients with HF. METHODS: The multicenter SchlaHF (Sleep-Disordered Breathing in Heart Failure) registry provides demographic and clinical data on chronic, stable, symptomatic patients with HF (New York Heart Association functional class ≥II; left ventricular rejection fraction ≤45%)...
February 2016: JACC. Heart Failure
https://www.readbyqxmd.com/read/26661645/rates-of-initial-acceptance-of-pap-masks-and-outcomes-of-mask-switching
#20
Adel Bachour, Pirjo Vitikainen, Paula Maasilta
PURPOSE: Recently, we noticed a considerable development in alleviating problems related to positive airway pressure (PAP) masks. In this study, we report on the initial PAP mask acceptance rates and the effects of mask switching on mask-related symptoms. METHODS: We prospectively collected all cases of mask switching in our sleep unit for a period of 14 months. At the time of the study, we used ResMed™ CPAP devices and masks. Mask switching was defined as replacing a mask used for at least 1 day with another type of mask...
May 2016: Sleep & Breathing, Schlaf & Atmung
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