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Postpartum haemorrhage

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https://www.readbyqxmd.com/read/28432736/severe-primary-autoimmune-thrombocytopenia-itp-in-pregnancy-a-national-cohort-study
#1
A Care, S Pavord, M Knight, Z Alfirevic
OBJECTIVE: To quantify UK incidence of severe ITP in pregnancy, determine current treatment strategies and establish maternal and neonatal morbidity and mortality associated with severe ITP in pregnancy. DESIGN: A prospective national cohort study SETTING: United Kingdom POPULATION: Women with severe ITP; defined as platelets <50 x 10(9) /l in pregnancy or antenatal treatment of isolated low platelets. METHODS: Data collected via United Kingdom Obstetric Surveillance System (UKOSS) between 1(st) June 2013-31(st) January 2015 from all UK Consultant led obstetric units...
April 22, 2017: BJOG: An International Journal of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/28424199/further-research-supports-association-between-antidepressant-use-and-elevated-risk-of-postpartum-haemorrhage
#2
Jane B Ford
No abstract text is available yet for this article.
April 19, 2017: Evidence-based Nursing
https://www.readbyqxmd.com/read/28421908/extravasating-uterine-pseudoaneurysm-a-rare-cause-of-postpartum-haemorrhage
#3
Sang Wook Yi
Postpartum haemorrhage (PPH) remains one of the leading causes of maternal death worldwide and can be classified as either immediate (primary) or delayed (secondary) according to the onset time - before or after 24 hours postpartum. Uterine pseudoaneurysm is a rare cause of PPH that has been suggested to arise from abnormal vascular regression and a recurrent vascular healing state, such as a vascular stricture and relaxation with thrombin deposits after placental expulsion. With advances in multidetector computed tomography, 3D-computed tomography with angiography can aid in identifying the location and originating vessels of the pseudoaneurysm via fast and clear 3D images...
May 2017: Journal of Obstetrics and Gynaecology: the Journal of the Institute of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/28413832/statistical-analysis-plan-for-the-woman-etaplat-study-effect-of-tranexamic-acid-on-platelet-function-and-thrombin-generation
#4
Kastriot Dallaku, Haleema Shakur, Phil Edwards, Danielle Beaumont, Ian Roberts, Sumaya Huque, Maria Delius, Ulrich Mansmann
Background. Postpartum haemorrhage (PPH) is a potentially life-threatening complication for women, and the leading cause of maternal mortality. Tranexamic acid (TXA) is an antifibrinolytic used worldwide to treat uterine haemorrhage and to reduce blood loss in general surgery. TXA may have effects on thrombin generation, platelet function and coagulation factors as a result of its inhibition on the plasmin. Methods. WOMAN ETAPlaT is a sub-study of the World Maternal Antifibrinolitic trial (WOMAN trial). All adult women clinically diagnosed with PPH after a vaginal delivery or caesarean section, are eligible for inclusion in the study...
December 15, 2016: Wellcome Open Research
https://www.readbyqxmd.com/read/28403951/successful-use-of-a-bakri-tamponade-balloon-in-the-treatment-of-puerperal-uterine-inversion-during-caesarean-section
#5
A J Vivanti, E Furet, J Nizard
Acute puerperal inversion of the uterus is a rare life-threatening obstetric emergency, especially during caesarean section. We present the case of a 30-year-old patient with acute puerperal inversion of the uterus that occurred during placental removal. After a quick reversion of the uterus, an immediate postpartum haemorrhage (PPH) due to massive uterine atony was observed. This atony impacted the whole uterus, with a very thin uterine myometrium. The use of a Bakri Tamponade Balloon use allowed treating extreme uterine atony, immediately stop haemorrhage, and prevent a possible risk of immediate recurrence...
January 2017: J Gynecol Obstet Hum Reprod
https://www.readbyqxmd.com/read/28384942/recent-advances-in-the-management-of-major-postpartum-haemorrhage-a-review
#6
REVIEW
P Reddi Rani, Jasmina Begum
Postpartum haemorrhage (PPH) is a leading cause of maternal mortality and morbidity worldwide and 75-90% of these haemorrhage results from uterine atony. Delayed and substandard obstetrics care can kill a woman within hours of Major Obstetric Haemorrhage (MOH). Prenatal identification of at risk women, prompt assessment of blood loss, effective management and involvement of multidisciplinary teams is of utmost importance to save the lives of these women. However, even with the best prenatal care, PPH occurs, it can occur without any risk factors...
February 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28338231/caesarean-risk-in-obese-women-at-term-a%C3%A2-retrospective-cohort-analysis
#7
Rachael Nugent, Caroline de Costa, Venkat Vangaveti
BACKGROUND: Obesity in pregnancy is a growing health problem conferring higher risk to both the woman and her infant. Internationally, peak bodies offer little guidance regarding the method and timing of delivery in these patients. Our hypothesis is that induction of labour (IOL) at term will not increase the caesarean section (CS) rate when compared to expectant management. AIMS: To compare perinatal outcomes between IOL and expectant management in obese women at term...
March 24, 2017: Australian & New Zealand Journal of Obstetrics & Gynaecology
https://www.readbyqxmd.com/read/28321338/frequency-risk-factors-and-adverse-fetomaternal-outcomes-of-placenta-previa-in-northern-tanzania
#8
Elizabeth Eliet Senkoro, Amasha H Mwanamsangu, Fransisca Seraphin Chuwa, Sia Emmanuel Msuya, Oresta Peter Mnali, Benjamin G Brown, Michael Johnson Mahande
Background and Objective. Placenta previa (PP) is a potential risk factor for obstetric hemorrhage, which is a major cause of fetomaternal morbidity and mortality in developing countries. This study aimed to determine frequency, risk factors, and adverse fetomaternal outcomes of placenta previa in Northern Tanzania. Methodology. A retrospective cohort study was conducted using maternally-linked data from Kilimanjaro Christian Medical Centre birth registry spanning 2000 to 2015. All women who gave birth to singleton infants were studied...
2017: Journal of Pregnancy
https://www.readbyqxmd.com/read/28317421/a-prospective-cohort-study-evaluating-the-cost-effectiveness-of-carbetocin-for-prevention-of-postpartum-haemorrhage-in-caesarean-sections
#9
Yasmin Luni, Aditya Borakati, Arti Matah, Katie Skeats, Padma Eedarapalli
Postpartum haemorrhage (PPH) is the leading cause of maternal mortality worldwide. Prophylaxis with oxytocic medication is recommended by the WHO to prevent its occurrence. Carbetocin is a newer oxytocic, with potential to lower PPH rates, reduce the total use of oxytocic drugs and lead to financial savings. Meta-analyses have confirmed a reduction in the use of additional oxytocic medication with the use of carbetocin compared to oxytocin. However, there are few studies evaluating the costs of carbetocin prophylaxis...
March 20, 2017: Journal of Obstetrics and Gynaecology: the Journal of the Institute of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/28317031/effect-of-tranexamic-acid-on-coagulation-and-fibrinolysis-in-women-with-postpartum-haemorrhage-woman-etac-protocol-and-statistical-analysis-plan-for-a-randomized-controlled-trial
#10
Haleema Shakur, Bukola Fawole, Modupe Kuti, Oladapo Olayemi, Adenike Bello, Olayinka Ogunbode, Taiwo Kotila, Chris O Aimakhu, Sumaya Huque, Meghann Gregg, Ian Roberts
Background: Postpartum haemorrhage (PPH) is a leading cause of maternal death. Tranexamic acid has the potential to reduce bleeding and a large randomized controlled trial of its effect on maternal health outcomes in women with PPH (The WOMAN trial) is ongoing. We will examine the effect of tranexamic acid on fibrinolysis and coagulation in a subset of WOMAN trial participants. Methods. Adult women with clinically diagnosed primary PPH after vaginal or caesarean delivery are eligible for inclusion in the WOMAN trial...
December 16, 2016: Wellcome Open Research
https://www.readbyqxmd.com/read/28292361/effectiveness-of-per-rectal-misoprostol-versus-intramuscular-oxytocin-for-prevention-of-primary-postpartum-haemorrhage
#11
Raheela Asmat, Tasneem Ashraf, Fazila Asmat, Shakila Asmat, Nagina Asmat
OBJECTIVE: To compare the effectiveness of per rectal misoprostol over oxytocin in primary postpartum haemorrhage (PPH). STUDY DESIGN: Randomised controlled trial study. PLACE AND DURATION OF STUDY: Gynaecology and Obstetrics Department, Unit IV, Bolan Medical Complex Hospital, Quetta, from September 2013 to February 2014. METHODOLOGY: Emergency obstetric patients receiving per rectal misoprostol (800 µgm) were named as group 'A' and those receiving 10 units oxytocin intramuscularly were labelled as group 'B'...
January 2017: Journal of the College of Physicians and Surgeons—Pakistan: JCPSP
https://www.readbyqxmd.com/read/28284877/midwifery-continuity-of-carer-in-an-area-of-high-socio-economic-disadvantage-in-london-a-retrospective-analysis-of-albany-midwifery-practice-outcomes-using-routine-data-1997-2009
#12
Caroline Se Homer, Nicky Leap, Nadine Edwards, Jane Sandall
OBJECTIVE: in 1997, The Albany Midwifery Practice was established within King's College Hospital NHS Trust in a South East London area of high social disadvantage. The Albany midwives provided continuity of care to around 216 women per year, including those with obstetric, medical or social risk factors. In 2009, the Albany Midwifery Practice was closed in response to concerns about safety, amidst much publicity and controversy. The aim of this evaluation was to examine trends and outcomes for all mothers and babies who received care from the practice from 1997-2009...
February 27, 2017: Midwifery
https://www.readbyqxmd.com/read/28262158/psychosis-as-a-late-manifestation-of-sheehan-s-syndrome
#13
Mukku Shiva Shanker Reddy, Abhinav Nahar, Harish Thippeswamy, Chaturvedi Santosh Kumar
Sheehan's syndrome occurs as a result of ischemic pituitary necrosis due to severe postpartum haemorrhage. It is one of the most common causes of hypopituitarism in underdeveloped or developing countries. Characteristic manifestations include failure to lactate or to resume menses, genital and axillary hair loss, asthenia and weakness, fine wrinkles around the eyes and lips, signs of premature aging, dry skin, hypopigmentation and other evidence of hypopituitarism. Uncommonly it can present with psychosis. There are only few case reports of psychoses in patients with Sheehan's syndrome...
February 2017: Asian Journal of Psychiatry
https://www.readbyqxmd.com/read/28250966/pph-butterfly-a-novel-device-to-treat-postpartum-haemorrhage-through-uterine-compression
#14
Caroline Cunningham, Peter Watt, Nasreen Aflaifel, Simon Collins, Dot Lambert, John Porter, Tina Lavender, Tony Fisher, Andrew Weeks
OBJECTIVE: Postpartum haemorrhage (PPH) is a significant cause of maternal morbidity and mortality. The most common cause is an inability of the uterus to contract adequately after childbirth. In bimanual compression (BMC), one hand is placed within the vagina and the other hand is on the abdominal wall to compress the uterus. It is effective, but very uncomfortable for the woman. We designed a device that could replicate BMC without inserting a hand vaginally, therefore being less invasive...
February 2017: BMJ Innovations
https://www.readbyqxmd.com/read/28208940/neurological-disorders-complicating-pregnancy-focus-on-obstetric-outcome
#15
Sandya Renukesh, Lavanya Rai
INTRODUCTION: Neurological disorders in pregnancy can be pregnancy related or can be caused by exacerbation of a pre-existing neurological condition or sometimes may even be detected for the first time during pregnancy in which it might be an incidental finding. The diagnosis and management of the neurological disorders in pregnancy is always a challenging task due to varied symptomatology and risks to the fetus. The evaluation and management should be performed in a stepwise fashion and requires multidisciplinary approach...
December 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28198084/single-dose-intravenous-iron-infusion-or-oral-iron-for-treatment-of-fatigue-after-postpartum-haemorrhage-a%C3%A2-randomized-controlled-trial
#16
C Holm, L L Thomsen, A Norgaard, J Langhoff-Roos
BACKGROUND AND OBJECTIVES: To evaluate the clinical efficacy of a single-dose intravenous infusion of iron isomaltoside compared with current treatment practice with oral iron measured by physical fatigue in women after postpartum haemorrhage. MATERIALS AND METHODS: Single-centre, open-label, randomized controlled trial. Participants received intravenous iron (n = 97) or oral iron (n = 99), and completed the Multidimensional Fatigue Inventory and Edinburgh Postnatal Depression Scale, and haematological and iron parameters were measured...
February 15, 2017: Vox Sanguinis
https://www.readbyqxmd.com/read/28195653/duration-of-second-stage-of-labour-at-term-and-pushing-time-risk-factors-for-postpartum-haemorrhage
#17
Emelie Looft, Marija Simic, Mia Ahlberg, Jonathan M Snowden, Yvonne W Cheng, Olof Stephansson
BACKGROUND: Prolonged labour is associated with increased risk of postpartum haemorrhage (PPH), but the role of active pushing time and the relation with management during labour remains poorly understood. METHODS: A population-based cohort study from electronic medical record data in the Stockholm-Gotland Region, Sweden. We included 57 267 primiparous women with singleton, term gestation, livebirths delivered vaginally in cephalic presentation in 2008-14. We performed multivariable Poisson regression to estimate the association between length of second stage, pushing time, and PPH (estimated blood loss >500 mL during delivery), adjusting for maternal, delivery, and fetal characteristics as potential confounders...
March 2017: Paediatric and Perinatal Epidemiology
https://www.readbyqxmd.com/read/28165183/assisted-reproductive-technologies-an-additional-risk-factor-for-severe-postpartum-haemorrhage
#18
A Mehrabadi
No abstract text is available yet for this article.
February 6, 2017: BJOG: An International Journal of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/28152987/trends-and-causes-of-maternal-mortality-in-ethiopia-during-1990-2013-findings-from-the-global-burden-of-diseases-study-2013
#19
Gizachew Assefa Tessema, Caroline O Laurence, Yohannes Adama Melaku, Awoke Misganaw, Sintayehu A Woldie, Abiye Hiruye, Azmeraw T Amare, Yihunie Lakew, Berihun M Zeleke, Amare Deribew
BACKGROUND: Maternal mortality is noticeably high in sub-Saharan African countries including Ethiopia. Continuous nationwide systematic evaluation and assessment of the problem helps to design appropriate policy and strategy in Ethiopia. This study aimed to investigate the trends and causes of maternal mortality in Ethiopia between 1990 and 2013. METHODS: We used the Global Burden of Diseases and Risk factors (GBD) Study 2013 data that was collected from multiple sources at national and subnational levels...
February 2, 2017: BMC Public Health
https://www.readbyqxmd.com/read/28133615/pregnancy-during-adolescence-and-associated-risks-an-8-year-hospital-based-cohort-study-2007-2014-in-romania-the-country-with-the-highest-rate-of-teenage-pregnancy-in-europe
#20
Demetra-Gabriela Socolov, Magdalena Iorga, Alexandru Carauleanu, Ciprian Ilea, Iolanda Blidaru, Lucian Boiculese, Razvan-Vladimir Socolov
Aim. To determine pregnancy and delivery outcomes among teenagers. Materials and Methods. An 8-year retrospective comparative hospital-based cohort study is analysing singleton pregnancy comorbidities and delivery parameters of a teenage group under the age of 20 compared with a young adult group 20-24 years of age in a university hospital. Results. Teenage is a risk factor for preterm birth <37 weeks (1.21 [1.08-1.35]), foetal growth restriction (1.34 [1.21-1.48]), episiotomy (1.27 [1.21-1.34]), uterine revision (1...
2017: BioMed Research International
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