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https://www.readbyqxmd.com/read/27641484/haploidentical-related-donor-hematopoietic-stem-cell-transplantation-with%C3%A2-post-transplantation-cyclophosphamide-for-dock8-deficiency
#1
Alexandra F Freeman, Nirali N Shah, Mark Parta, Helen C Su, Alessandra Brofferio, Irma Gradus-Pizlo, Sabah Butty, Thomas E Hughes, David E Kleiner, Daniele Avila, Theo Heller, Heidi H Kong, Steven M Holland, Dennis D Hickstein
No abstract text is available yet for this article.
September 15, 2016: Journal of Allergy and Clinical Immunology in Practice
https://www.readbyqxmd.com/read/26453586/haploidentical-hematopoietic-cell-transplantation-with-post-transplant-cyclophosphamide-in-a-patient-with-chronic-granulomatous-disease-and-active-infection-a-first-report
#2
Mark Parta, Dianne Hilligoss, Corin Kelly, Nana Kwatemaa, Narda Theobald, Harry Malech, Elizabeth M Kang
PURPOSE: We describe haploidentical hematopoietic cell transplantation (HCT) with high-dose post-transplant cyclophosphamide (PTCy) in a boy with x-linked chronic granulomatous disease (CGD). METHODS: A persistent and life-threatening fungal infection was the indication for HSCT. Non-myeloablative conditioning with PTCy (50 mg/kg days 3 and 4) was used in the absence of fully matched donors. RESULTS: Engraftment occurred on day 24. The patient experienced Grade 2 graft-versus-host disease of the skin and gastrointestinal tract and CMV infection, both of which were controlled...
October 2015: Journal of Clinical Immunology
https://www.readbyqxmd.com/read/25885978/a-comparative-study-of-the-efficacy-of-intravenous-paracetamol-and-dexmedetomidine-on-peri-operative-hemodynamics-and-post-operative-analgesia-for-patients-undergoing-laparoscopic-cholecystectomy
#3
Sarbari Swaika, Nilakshi Parta, Surajit Chattopadhyay, Bikash Bisui, Sumantra Sarathi Banarjee, Somjit Chattarjee
BACKGROUND: Unrelieved post-operative pain may result in the physical suffering as well as multiple physiological and the psychological consequences, which may adversely affect the peri-operative outcome and contribute to increase the length of stay in hospital. OBJECTIVES: We designed this study to evaluate the effect of IV Paracetamol and Dexmedetomidine as multimodal analgesic technique on post-operative analgesia and to reduce the consumption of the systemic opioid and its adverse effects in cases of laparoscopic cholecystectomy...
September 2013: Anesthesia, Essays and Researches
https://www.readbyqxmd.com/read/25636378/matched-related-and-unrelated-donor-hematopoietic-stem-cell-transplantation-for-dock8-deficiency
#4
Jennifer Cuellar-Rodriguez, Alexandra F Freeman, Jennifer Grossman, Helen Su, Mark Parta, Heardley Murdock, Nirali Shah, Catherine Bollard, Heidi H Kong, Niki Moutsopoulos, Kelly Stone, Juan Gea-Banacloche, Steven M Holland, Dennis D Hickstein
We performed allogeneic hematopoietic stem cell transplantation in 6 patients with mutations in the dedicator-of-cytokinesis-8 (DOCK8) gene using a myeloablative conditioning regimen consisting of busulfan 3.2 mg/kg/day i.v. for 4 days and fludarabine 40 mg/m(2)/day for 4 days. Three patients received allografts from matched related donors and 3 patients from matched unrelated donors. Two patients received peripheral blood stem cells and 4 patients bone marrow hematopoietic stem cells. Tacrolimus and short-course methotrexate on days 1, 3, 6, and 11 were used for graft-versus-host-disease (GVHD) prophylaxis...
June 2015: Biology of Blood and Marrow Transplantation
https://www.readbyqxmd.com/read/25111582/nonmyeloablative-allogeneic-hematopoietic-stem-cell-transplantation-for-gata2-deficiency
#5
Jennifer Grossman, Jennifer Cuellar-Rodriguez, Juan Gea-Banacloche, Christa Zerbe, Katherine Calvo, Thomas Hughes, Fran Hakim, Kristen Cole, Mark Parta, Alexandra Freeman, Steven M Holland, Dennis D Hickstein
We treated 14 patients with GATA2 deficiency using a nonmyeloablative allogeneic hematopoietic stem cell transplantation regimen. Four patients received peripheral blood stem cells from matched related donors (MRD), 4 patients received peripheral blood stem cells from matched unrelated donors (URD), 4 patients received hematopoietic stem cells from umbilical cord blood donors (UCB), and 2 patients received bone marrow cells from haploidentical related donors. MRD and URD recipients received conditioning with 3 days of fludarabine and 200 cGy total body irradiation (TBI)...
December 2014: Biology of Blood and Marrow Transplantation
https://www.readbyqxmd.com/read/7620852/absorption-of-polychlorinated-biphenyls-dibenzo-p-dioxins-and-dibenzofurans-by-breast-fed-infants
#6
COMPARATIVE STUDY
P Dahl, G Lindström, K Wiberg, C Rappe
The absorption of polychlorinated biphenyls, dibenzo-p-dioxins and dibenzofurans was studied in four breast-fed infants. The absorption was measured by comparing the estimated total intake and the excretion in faeces, during 48 hours, at three different time points; 1, 2 and 3 months post parta. The levels of the analysed compounds in the human milk are typical for Sweden, i.e approximately 20 ppt toxic equivalents for the dibenzo-p-dioxins and dibenzofurans and for the polychlorinated biphenyls approximately 16 ppt toxic equivalents...
June 1995: Chemosphere
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