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Dyslipidaemia

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https://www.readbyqxmd.com/read/29333896/cataract-surgery-in-hiv-seropositive-patients-long-term-follow-up
#1
Massimo Accorinti, Michela Cecere, Andrea Scala, Maria Pia Pirraglia
PURPOSE: To study epidemiology and clinical findings of cataract in HIV+ patients. METHODS: A total of 32 HIV+ patients, 11 with uveitis/retinitis before surgery and 21 without, mean follow-up 44.9 ± 36.6 months, and 114 HIV- patients, 57 with uveitis/retinitis before surgery and 57 without, were retrospectively compared. RESULTS: Visual acuity improved in all HIV+ patients (p < 0.001), who were younger (p = 0.01) and more frequently males (p = 0...
January 15, 2018: Ocular Immunology and Inflammation
https://www.readbyqxmd.com/read/29333686/predicting-hypertension-among-korean-cancer-survivors-a-nationwide-population-based-study
#2
Y-H Kim, K-H Cho, K H Kim, E J Ryu, K D Han, J-S Kim
Hypertension is the most common comorbidity among cancer survivors, although there is no model for predicting hypertension in this population. Therefore, we developed a model for predicting hypertension using data from 6,480 Korean cancer survivors who were ≥20 years old. The odds ratios (ORs) for hypertension were calculated using stepwise logistic regression analyses, and a nomogram was generated to predict hypertension. Hypertension was independently associated with an age of ≥65 years (OR: 3.058), male gender (OR: 1...
January 15, 2018: European Journal of Cancer Care
https://www.readbyqxmd.com/read/29333610/clinical-features-and-treatment-of-nonalcoholic-fatty-liver-disease-across-the-asia-pacific-region-the-go-asia-initiative
#3
W-K Chan, S Treeprasertsuk, K Imajo, A Nakajima, Y Seki, K Kasama, S Kakizaki, J-G Fan, M J Song, S K Yoon, Y-Y Dan, L Lesmana, K-Y Ho, K-L Goh, V W-S Wong
BACKGROUND: The Gut and Obesity Asia (GO ASIA) workgroup was formed to study the relationships between obesity and gastrointestinal diseases in the Asia Pacific region. AIM: To study factors associated with nonalcoholic steatohepatitis (NASH) and advanced fibrosis, and medical treatment of biopsy-proven nonalcoholic fatty liver disease (NAFLD) patients. METHODS: Retrospective study of biopsy-proven NAFLD patients from centres in the GO ASIA Workgroup...
January 14, 2018: Alimentary Pharmacology & Therapeutics
https://www.readbyqxmd.com/read/29330987/pattern-of-dyslipidaemia-and-its-association-with-hypovitaminosis-d-in-type-2-diabetes-mellitus
#4
Farhat Bashir, Zia Ullah Khan, Naresh Kumar Seetlani, Zaman Sheikh
BACKGROUND: Macrovascular atherosclerosis is an important long-term complication of type 2 diabetes mellitus. Concurrent dyslipidaemia acts as an additional risk factor for these complications. Hypovitaminosis D has been associated with adverse cardiovascular events. These modifiable risk factors of cardiovascular disease are inter-related. In the presence of an increasing incidence of type 2 diabetes mellitus and its associated metabolic abnormalities and widespread vitamin D deficiency in Pakistan, this association needs to be investigated...
October 2017: Journal of Ayub Medical College, Abbottabad: JAMC
https://www.readbyqxmd.com/read/29327345/serum-lipoprotein-a-predicts-acute-coronary-syndromes-in-patients-with-severe-carotid-stenosis
#5
Fabio Rigamonti, Federico Carbone, Fabrizio Montecucco, Aldo Bonaventura, Luca Liberale, Fabienne Burger, Aline Roth, Maria Bertolotto, Giovanni Spinella, Bianca Pane, Domenico Palombo, Aldo Pende, Franco Dallegri, François Mach, Stefano Bertolini, Livia Pisciotta
Different cut-off values of serum lipoprotein(a) [Lp(a)] were recently identified in order to better stratify cardiovascular risk categories. Both pathophysiological and prognostic values of Lp(a) remain unclear. Here, the prognostic value of Lp(a) and its correlation with intraplaque features were assessed in patients with severe carotid artery stenosis undergoing endarterectomy (n=180). The cut-off value of 10 mg/dL for serum Lp(a) was selected to predict 24-month follow-up acute coronary syndrome (ACS). In addition, the association between serum Lp(a) and intraplaque lipids, collagen, inflammatory and vascular cells was assessed...
January 11, 2018: European Journal of Clinical Investigation
https://www.readbyqxmd.com/read/29324354/an-in-depth-prognostic-analysis-of-baseline-blood-lipids-in-predicting-postoperative-colorectal-cancer-mortality-the-fiesta-study
#6
Feng Peng, Dan Hu, Xiandong Lin, Gang Chen, Binying Liang, Ying Chen, Chao Li, Hejun Zhang, Yan Xia, Jinxiu Lin, Xiongwei Zheng, Wenquan Niu
BACKGROUND: Dyslipidaemia is key to colorectal carcinogenesis, and the prediction of baseline triglycerides (TG), total cholesterol (TC), high- and low-density lipoprotein cholesterol (HDLC and LDLC) for postsurgical colorectal cancer mortality has not been researched. OBJECTIVES: We attempted to re-analyse the FIESTA database to assess the prognostic value of three informative lipid derivatives - AI (atherogenic index: (TC - HDLC)/HDLC), THR (TG/HDLC) and LHR (LDLC/HDLC) in predicting colorectal cancer mortality...
January 8, 2018: Cancer Epidemiology
https://www.readbyqxmd.com/read/29317116/giant-coronary-aneurysm-culprit-of-an-acute-coronary-syndrome
#7
Iván J Núñez-Gil, Pedro Marcos Alberca, Nieves Gonzalo, Luis Nombela-Franco, Pablo Salinas, Antonio Fernández-Ortiz
A 66-year-old male ex-smoker with hypertension, type 2 diabetes mellitus and dyslipidaemia was admitted due to a non-ST segment elevation myocardial infarction. The catheterisation depicted an extensive and calcified disease: chronic total obstruction of the right coronary and severe disease with a giant aneurysm at the first marginal branch as the culprit vessel. After discussion, the right coronary was treated before the circumflex-giant aneurysm was closed with a stent graft and its multiple severe stenosis solved with two drug-eluting stents...
January 6, 2018: Portuguese Journal of Cardiology: An Official Journal of the Portuguese Society of Cardiology
https://www.readbyqxmd.com/read/29312456/association-of-sleep-duration-with-apolipoproteins-and-the-apolipoprotein-b-a1-ratio-the-china-health-and-nutrition-survey
#8
Huihui Ren, Zhelong Liu, Xinrong Zhou, Gang Yuan
Background: Short sleep duration has been related to established cardiovascular risk factors, likely obesity, diabetes, hypertension and dyslipidaemia. However, to the best of our knowledge, the associations between sleep duration and apolipoprotein concentrations and their ratios have not been investigated to date. This study aimed to explore the independent relationship of sleep duration with apolipoprotein (apo) A1, apoB and the apoB/apoA1 ratio in a Chinese adult population. Methods: Data from 7381 participants, aged 18 to 75 years, from the National Health and Nutrition Survey 2009 were analysed in this cross-sectional study...
2018: Nutrition & Metabolism
https://www.readbyqxmd.com/read/29310742/utility-of-arterial-stiffness-assessment-in-children
#9
Chaitanya Panchangam, Eric Dean Merrill, Geetha Raghuveer
Atherosclerotic cardiovascular disease is a leading cause of death and disability worldwide, and the atherosclerotic process begins in childhood. Prevention or containment of risk factors that accelerate atherosclerosis can delay the development of atherosclerotic cardiovascular disease. Although current recommendations are to periodically screen for commonly prevailing risk factors for atherosclerosis in children, a single test that could quantify the cumulative effect of all risk factors on the vasculature, thus assessing arterial health, would be helpful in further stratifying risk...
January 9, 2018: Cardiology in the Young
https://www.readbyqxmd.com/read/29305561/trends-in-cardiovascular-risk-factor-and-disease-prevalence-in-patients-undergoing-non-cardiac-surgery
#10
Nathaniel R Smilowitz, Navdeep Gupta, Yu Guo, Joshua A Beckman, Sripal Bangalore, Jeffrey S Berger
OBJECTIVES: Cardiovascular risk factors are prevalent in the population undergoing non-cardiac surgery. Changes in perioperative cardiovascular risk factor profiles over time are unknown. The objective of this study was to evaluate national trends in cardiovascular risk factors and atherosclerotic cardiovascular disease (ASCVD) among patients undergoing non-cardiac surgery. METHODS: Adults aged ≥45 years old who underwent non-cardiac surgery were identified using the US National Inpatient Sample from 2004 to 2013...
January 5, 2018: Heart: Official Journal of the British Cardiac Society
https://www.readbyqxmd.com/read/29303009/dyslipidaemia-in-the-elderly-to-treat-or-not-to-treat
#11
Niki Katsiki, Genovefa Kolovou, Pablo Perez-Martinez, Dimitri P Mikhailidis
The elderly population (i.e. aged ≥ 65 years) is increasing worldwide. Ageing is associated with a higher incidence and prevalence of cardiovascular disease (CVD). Areas covered: The prevalence of CVD risk factors including type 2 diabetes mellitus, hypertension and dyslipidaemia also increases with advancing age, contributing to the higher absolute CVD risk observed in the elderly. The present narrative review comments on the associations of dyslipidaemia with CVD as well as the effects of lifestyle measures and lipid-lowering drugs on lipids and CVD risk with a special focus on the elderly population...
January 5, 2018: Expert Review of Clinical Pharmacology
https://www.readbyqxmd.com/read/29300982/gender-and-schooling-inequalities-in-risk-and-protective-factors-for-chronic-diseases-among-brazilian-adults
#12
Carla C Enes, Luciana B Nucci
Background: There is consistent evidence showing that low socioeconomic level, both at the individual and contextual levels, is an important predictor of morbidity and mortality due to noncommunicable diseases. Objective: To identify gender and schooling inequalities in the distribution of risk and protective factors for chronic diseases among Brazilian adults. Methods: This study included data from 97 468 individuals interviewed in 2012 and 2013 from the Surveillance System of Risk and Protective Factors for Chronic Diseases (VIGITEL)...
December 29, 2017: Journal of Public Health
https://www.readbyqxmd.com/read/29290214/dietary-management-of-dyslipidaemias-is-there-any-evidence-for-cardiovascular-benefit
#13
REVIEW
Panagiotis Anagnostis, Stavroula A Paschou, Dimitrios G Goulis, Vasilios G Athyros, Asterios Karagiannis
Specific dietary strategies are the mainstay of management in most cases of dyslipidaemia, prior to or simultaneously with the initiation of a lipid-lowering agent. The exact approach differs according to the type of dyslipidaemia. In particular, a reduction in carbohydrates (mainly foods with a high glycaemic index) and their substitution with mono- and polyunsaturated fatty acids is the main strategy in patients with high levels of triglycerides (Tg) and/or low levels of high-density lipoprotein cholesterol (HDL-c)...
February 2018: Maturitas
https://www.readbyqxmd.com/read/29287992/comorbidity-concomitant-medication-use-of-resources-and-healthcare-costs-associated-with-chronic-hepatitis-c-virus-carriers-in-spain
#14
Antoni Sicras-Mainar, Ruth Navarro-Artieda, Marc Sáez-Zafra
OBJECTIVES: To assess the comorbidity, concomitant medications, healthcare resource use and healthcare costs of chronic hepatitis C virus patients in the Spanish population. PATIENTS AND METHODS: Retrospective, observational, non-interventional study. Patients included were≥18 years of age who accessed medical care between 2010-2013. Patients were divided into 2 groups based on the presence or absence of liver cirrhosis. The follow-up period was 12 months. Main assessment criteria included general comorbidity level (determined by the resource utilisation band score) and prevalence of specific comorbidities, concomitant medications, healthcare resource use and healthcare costs...
December 26, 2017: Gastroenterología y Hepatología
https://www.readbyqxmd.com/read/29284464/potential-use-of-telephone-based-survey-for-non-communicable-disease-surveillance-in-sri-lanka
#15
H M M Herath, N P Weerasinghe, T P Weerarathna, A Hemantha, A Amarathunga
BACKGROUND: Telephone survey (TS) has been a popular tool for conducting health surveys, particularly in developed countries. However, the feasibility, and reliability of TS are not adequately explored in Sri Lanka. The main aim of this study is to assess the effectiveness of telephone-based survey in estimating the prevalence of common non-communicable diseases (NCDs) in Sri Lanka. METHODS: We carried out an observational cross-sectional study using telephone interview method in Galle district, Sri Lanka...
December 29, 2017: BMC Public Health
https://www.readbyqxmd.com/read/29281159/non-alcoholic-fatty-liver-disease-is-associated-with-stroke-severity-and-progression-of-brainstem-infarctions
#16
Haiyan Li, Biao Hu, Wei Lei, Li Zhou, Lei Zhang, Yinyao Lin, Bing Qin, Yongqiang Dai, Zhengqi Lu
BACKGROUND: Non-alcoholic fatty liver disease (NAFLD) is closely correlated to visceral obesity, dyslipidaemia, insulin resistance, and type 2 diabetes mellitus (T2DM). We sought to assess the association between a specific stroke subgroup, brainstem infarctions (BSIs), and NAFLD. Furthermore, we evaluated whether NAFLD is an independent risk factor in patients with BSIs. METHODS: NAFLD was assessed in 306 radiologically confirmed BSIs patients via liver ultrasound...
December 27, 2017: European Journal of Neurology: the Official Journal of the European Federation of Neurological Societies
https://www.readbyqxmd.com/read/29280189/adiponectin-concentration-data-improve-the-estimation-of-atherosclerotic-risk-in-normal-and-in-overweight-subjects
#17
Adriana Bertolami, José C de Lima-Júnior, Riobaldo M Cintra, Luiz S Carvalho, Carolina de C Gonzaga, Martha L Sulzbach, Ana C G P Petisco, José E M Barbosa, André A Faludi, Jorge Plutzky, Marcelo C Bertolami, Andrei C Sposito
BACKGROUND: The combinations of adipokines and body mass parameters to estimate carotid atherosclerotic disease have not been completely delineated. OBJECTIVE: To test the combinations of well-established, easily accessible body mass indices and circulating biomarkers to identify increased carotid intima-media thickness (cIMT) in a primary prevention setting. DESIGN AND PATIENTS: In a cross-sectional analysis of 339 asymptomatic individuals with no history of cardiovascular events, inflammatory and insulin sensitivity biomarkers as well as adipokine levels were measured and combined with body mass parameters to evaluate the best marker for increased cIMT...
December 27, 2017: Clinical Endocrinology
https://www.readbyqxmd.com/read/29279144/mild-hyperbilirubinaemia-as-an-endogenous-mitigator-of-overweight-and-obesity-implications-for-improved-metabolic-health
#18
Nazlisadat Seyed Khoei, Annemarie Grindel, Marlies Wallner, Christine Mölzer, Daniel Doberer, Rodrig Marculescu, Andrew Bulmer, Karl-Heinz Wagner
BACKGROUND AND AIMS: Mild endogenous elevation of unconjugated bilirubin (UCB) as seen in Gilbert's syndrome (GS), might mitigate cardiovascular disease (CVD) risk factors including overweight/obesity. This study aimed to determine whether hyperbilirubinaemia is linked to improved anthropometric data and lipid profile. METHODS: Our study considered GS and age-/gender-matched healthy controls (n = 248). Additionally, obese female type 2 diabetic patients (DM2) (n = 26) were included as a "disease control group"...
December 14, 2017: Atherosclerosis
https://www.readbyqxmd.com/read/29278986/reach-and-effectiveness-of-the-heartbeat-connections-telemedicine-pilot-program
#19
Gretchen A Benson, Abbey Sidebottom, Arthur Sillah, Jackie L Boucher, Michael D Miedema, Thomas Knickelbine, Jeffrey J VanWormer
Introduction Innovative care delivery programs that support primary care providers are needed to reduce the burden of cardiovascular disease (CVD). HeartBeat Connections (HBC) is a primary prevention telemedicine program utilizing registered dietitian nutritionists (RDNs) and registered nurses (RNs) to deliver health coaching and medication therapy protocols for dyslipidaemia and hypertension among patients at high risk for developing CVD. Methods This retrospective cohort study documents the reach and six-month effectiveness of the HBC program for improving CVD risk factors...
January 1, 2017: Journal of Telemedicine and Telecare
https://www.readbyqxmd.com/read/29260581/dietary-phenolic-acids-reverse-insulin-resistance-hyperglycaemia-dyslipidaemia-inflammation-and-oxidative-stress-in-high-fructose-diet-induced-metabolic-syndrome-rats
#20
Oluwayemisi B Ibitoye, Taofeek O Ajiboye
This study investigated the influence of caffeic, ferulic, gallic and protocatechuic acids on high-fructose diet-induced metabolic syndrome in rats. Oral administration of the phenolic acids significantly reversed high-fructose diet-mediated increase in body mass index and blood glucose. Furthermore, phenolic acids restored high-fructose diet-mediated alterations in metabolic hormones (insulin, leptin and adiponectin). Similarly, elevated tumour necrosis factor-α, interleukin-6 and -8 were significantly lowered...
December 20, 2017: Archives of Physiology and Biochemistry
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