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https://www.readbyqxmd.com/read/29764965/effect-of-treat-to-target-strategies-aiming-at-remission-of-arterial-stiffness-in-early-rheumatoid-arthritis-a-randomized-controlled-study
#1
Lydia Ho-Pui Tam, Qing Shang, Edmund Kwok-Ming Li, Priscilla Ching-Han Wong, Kitty Yan Kwok, Emily Wai-Lin Kun, Isaac Cheuk-Wan Yim, Violet Ka-Lai Lee, Ronald Man-Lung Yip, Steve Hin-Ting Pang, Virginia Weng-Nga Lao, Queenie Wah-Yan Mak, Isaac Tsz-Ho Cheng, Xerox Sze-Lok Lau, Tena Ka-Yan Li, Tracy Yaner Zhu, Alex Pui-Wai Lee, Lai-Shan Tam
OBJECTIVE: To determine the efficacy of 2 tight control treatment strategies aiming at Simplified Disease Activity Score (SDAI) remission (SDAI ≤ 3.3) compared to 28-joint count Disease Activity Score (DAS28) remission (DAS28 < 2.6) in the prevention of arterial stiffness in patients with early rheumatoid arthritis (RA). METHODS: This was an open-label study in which 120 patients with early RA were randomized to receive 1 year of tight control treatment. Group 1 (n = 60) aimed to achieve SDAI ≤ 3...
May 15, 2018: Journal of Rheumatology
https://www.readbyqxmd.com/read/29763980/arterial-stiffness-in-people-with-type-2-diabetes-and-obstructive-sleep-apnoea
#2
M Hvelplund Kristiansen, A M Banghøj, E Laugesen, L Tarnow
AIMS: To examine whether people with Type 2 diabetes with concurrent obstructive sleep apnoea have increased arterial stiffness as compared with people with Type 2 diabetes without obstructive sleep apnoea. METHODS: In a study with a case-control design, 40 people with Type 2 diabetes and treatment-naïve moderate to severe obstructive sleep apnoea (Apnoea-Hypopnoea Index ≥15) and a control group of 31 people with Type 2 diabetes without obstructive sleep apnoea (Apnoea-Hypopnoea Index <5) were examined...
May 15, 2018: Diabetic Medicine: a Journal of the British Diabetic Association
https://www.readbyqxmd.com/read/29762567/chemical-elemental-analysis-of-single-acoustic-levitated-water-droplets-by-laser-induced-breakdown-spectroscopy
#3
Victor Contreras, Ricardo Valencia, Jairo Peralta, H Sobral, M A Meneses-Nava, Horacio Martinez
Laser-induced breakdown spectroscopy is presented for trace element detection of liquid samples by analyzing a single droplet levitated by ultrasonic waves. A single liquid droplet is placed in the node of a standing acoustic wave produced by a uniaxial levitator for further chemical analysis. The acoustic levitator consists of a commercial Langevin-type transducer, attached to a concave mechanical amplifier, and a concave reflector. A micro-syringe was used to manually place individual liquid droplet samples in the acoustic levitation system...
May 15, 2018: Optics Letters
https://www.readbyqxmd.com/read/29761317/high-sodium-intake-and-sodium-to-potassium-ratio-may-be-linked-to-subsequent-increase-in-vascular-damage-in-adults-aged-40-years-and-older-the-korean-multi-rural-communities-cohort-mrcohort
#4
Sukyoung Jung, Mi Kyung Kim, Jinho Shin, Bo Youl Choi, Young-Hoon Lee, Dong Hoon Shin, Min-Ho Shin
PURPOSE: Subclinical vascular damage is a chronic intermediate process in cardiovascular disease (CVD) and high sodium (Na) has been regarded as an adverse factor in subclinical vascular health; however, the longitudinal relationship between Na intake and subclinical vascular damage has not been studied. We aimed to evaluate the longitudinal relationship of dietary Na intake and sodium to potassium ratio (Na:K) with brachial-ankle pulse wave velocity (baPWV) and carotid intima media thickness (cIMT) in healthy adults aged 40 years and older in Korea...
May 14, 2018: European Journal of Nutrition
https://www.readbyqxmd.com/read/29761092/validation-of-a-piezoelectric-sensor-array-based-device-for-measurement-of-carotid-femoral-pulse-wave-velocity-the-philips-prototype
#5
Shao-Kun Xu, Xiang-Fei Hong, Yi-Bang Cheng, Chang-Yuan Liu, Yan Li, Bin Yin, Ji-Guang Wang
Background: Multiple piezoelectric pressure mechanotransducers topologized into an array might improve efficiency and accuracy in collecting arterial pressure waveforms for measurement of pulse wave velocity (PWV). Objective: In the present study, we validated a piezoelectric sensor array-based prototype (Philips) against the validated and clinically widely used Complior device (Alam Medical). Methods: We recruited 33 subjects with a wide distribution of PWV...
March 2018: Pulse (Basel, Switzerland)
https://www.readbyqxmd.com/read/29761091/increase-in-the-arterial-velocity-pulse-index-of-patients-with-peripheral-artery-disease
#6
Naotaka Murata, Kazuki Shiina, Jun Yamashita, Nobuhiro Tanaka, Taishiro Chikamori, Akira Yamashina, Hirofumi Tomiyama
Background: Recently, a simple parameter calculated from the brachial pressure waveform recorded using an oscillometric device (arterial velocity pulse index [AVI]: ratio of the forward/reflected pressure wave amplitudes) has become available to assess the pathophysiological abnormalities associated with vascular damage. Peripheral artery disease (PAD) represents one of the disease entities associated with the advanced stages of atherosclerotic vascular damage. The present study was conducted to examine whether an increase in the AVI might be influenced by the presence of PAD...
March 2018: Pulse (Basel, Switzerland)
https://www.readbyqxmd.com/read/29761082/associations-between-type-2-diabetes-mellitus-and-arterial-stiffness-a-prospective-analysis-based-on-the-maine-syracuse-study
#7
Merrill F Elias, Georgina E Crichton, Peter J Dearborn, Michael A Robbins, Walter P Abhayaratna
Background: The aim of this study was to investigate prospective associations between type 2 diabetes mellitus status and the gold standard non-invasive method for ascertaining arterial stiffness, carotid femoral pulse wave velocity. Methods: The prospective analysis employed 508 community-dwelling participants (mean age 61 years, 60% women) from the Maine-Syracuse Longitudinal Study. Pulse wave velocity at wave 7 (2006-2010) was compared between those with type 2 diabetes mellitus at wave 6 (2001-2006) ( n = 52) and non-diabetics at wave 6 ( n = 456), with adjustment for demographic factors, cardiovascular risk factors and lifestyle- and pulse wave velocity-related factors...
March 2018: Pulse (Basel, Switzerland)
https://www.readbyqxmd.com/read/29760461/arterial-stiffness-not-systolic-blood-pressure-increases-with-age-in-native-papuan-populations
#8
Akio Ishida, Michiko Fujisawa, Eva Garcia Del Saz, Kiyohito Okumiya, Yumi Kimura, Indrajaya Ida Bagus Manuaba, Marthen Ferry Kareth, Andreas Lallo Rantetampang, Yusuke Ohya, Kozo Matsubayashi
Systolic blood pressure (SBP) and arterial stiffness are closely related and may behave reciprocally as cause or effect, interacting in a vicious cycle. Both SBP and arterial stiffness increase with age in populations in most developed countries. However, the age-related increase in SBP appears to be absent in indigenous populations, partially because of their lifelong low-sodium and high-potassium diets, whereas age-related arterial stiffening in these populations remains to be determined. We performed a field survey of the indigenous population of Soroba, a small village located in the central highlands of Papua, Indonesia...
May 14, 2018: Hypertension Research: Official Journal of the Japanese Society of Hypertension
https://www.readbyqxmd.com/read/29758957/non-invasive-continuous-blood-pressure-measurement-based-on-mean-impact-value-method-bp-neural-network-and-genetic-algorithm
#9
Xia Tan, Zhong Ji, Yadan Zhang
BACKGROUND: Non-invasive continuous blood pressure monitoring can provide an important reference and guidance for doctors wishing to analyze the physiological and pathological status of patients and to prevent and diagnose cardiovascular diseases in the clinical setting. Therefore, it is very important to explore a more accurate method of non-invasive continuous blood pressure measurement. OBJEVTIVE: To address the shortcomings of existing blood pressure measurement models based on pulse wave transit time or pulse wave parameters, a new method of non-invasive continuous blood pressure measurement - the GA-MIV-BP neural network model - is presented...
April 25, 2018: Technology and Health Care: Official Journal of the European Society for Engineering and Medicine
https://www.readbyqxmd.com/read/29755714/identification-of-cerebral-artery-stenosis-using-bilateral-photoplethysmography
#10
Hyun Goo Kang, Seogki Lee, Han Uk Ryu, Youngsuk Shin
Cerebral artery stenosis is currently diagnosed by transcranial Doppler (TCD), computed tomographic angiography (CTA), or magnetic resonance angiography (MRA). CTA exposes a patient to radiation, while CTA and MRA are invasive and side effects were related to contrast medium use. This study aims to provide a technique that can simply discriminate between people with normal blood vessels and those with cerebral artery stenosis using photoplethysmography (PPG), which is noninvasive and inexpensive. Moreover, the measurement takes only 120 seconds and is conducted on the fingers...
2018: Journal of Healthcare Engineering
https://www.readbyqxmd.com/read/29755590/wide-pulse-high-frequency-low-intensity-neuromuscular-electrical-stimulation-has-potential-for-targeted-strengthening-of-an-intrinsic-foot-muscle-a-feasibility-study
#11
Darren C James, Matthew C Solan, Katya N Mileva
Background: Strengthening the intrinsic foot muscles is a poorly understood and largely overlooked area. In this study, we explore the feasibility of strengthening m . abductor hallucis (AH) with a specific paradigm of neuromuscular electrical stimulation; one which is low-intensity in nature and designed to interleave physiologically-relevant low frequency stimulation with high-frequencies to enhance effective current delivery to spinal motoneurones, and enable a proportion of force produced by the target muscle to be generated from a central origin...
2018: Journal of Foot and Ankle Research
https://www.readbyqxmd.com/read/29750877/respiratory-induced-hemodynamic-changes-measured-by-whole-body-multichannel-impedance-plethysmography
#12
P Langer, P Jurák, V Vondra, J Halámek, M Mešťaník, I Tonhajzerová, I Viščor, L Soukup, M Matejkova, E Závodná, P Leinveber
The cardiovascular system is described by parameters including blood flow, blood distribution, blood pressure, heart rate and pulse wave velocity. Dynamic changes and mutual interactions of these parameters are important for understanding the physiological mechanisms in the cardiovascular system. The main objective of this study is to introduce a new technique based on parallel continuous bioimpedance measurements on different parts of the body along with continuous blood pressure, ECG and heart sound measurement during deep and spontaneous breathing to describe interactions of cardiovascular parameters...
May 10, 2018: Physiological Research
https://www.readbyqxmd.com/read/29750272/gut-microbial-diversity-is-associated-with-lower-arterial-stiffness-in-women
#13
Cristina Menni, Chihung Lin, Marina Cecelja, Massimo Mangino, Maria Luisa Matey-Hernandez, Louise Keehn, Robert P Mohney, Claire J Steves, Tim D Spector, Chang-Fu Kuo, Phil Chowienczyk, Ana M Valdes
Aims: The gut microbiome influences metabolic syndrome (MetS) and inflammation and is therapeutically modifiable. Arterial stiffness is poorly correlated with most traditional risk factors. Our aim was to examine whether gut microbial composition is associated with arterial stiffness. Methods and results: We assessed the correlation between carotid-femoral pulse wave velocity (PWV), a measure of arterial stiffness, and gut microbiome composition in 617 middle-aged women from the TwinsUK cohort with concurrent serum metabolomics data...
May 9, 2018: European Heart Journal
https://www.readbyqxmd.com/read/29744617/cardiac-magnetic-resonance-assessment-of-central-and-peripheral-vascular-function-in-patients-undergoing-renal-sympathetic-denervation-as-predictor-for-blood-pressure-response
#14
Karl Fengler, Karl-Philipp Rommel, Stephan Blazek, Maximilian Von Roeder, Christian Besler, Christian Lücke, Matthias Gutberlet, Jennifer Steeden, Michael Quail, Steffen Desch, Holger Thiele, Vivek Muthurangu, Philipp Lurz
BACKGROUND: Most trials regarding catheter-based renal sympathetic denervation (RDN) describe a proportion of patients without blood pressure response. Recently, we were able to show arterial stiffness, measured by invasive pulse wave velocity (IPWV), seems to be an excellent predictor for blood pressure response. However, given the invasiveness, IPWV is less suitable as a selection criterion for patients undergoing RDN. Consequently, we aimed to investigate the value of cardiac magnetic resonance (CMR) based measures of arterial stiffness in predicting the outcome of RDN compared to IPWV as reference...
May 9, 2018: Clinical Research in Cardiology: Official Journal of the German Cardiac Society
https://www.readbyqxmd.com/read/29743118/arterial-stiffness-in-adults-with-steady-state-bronchiectasis-association-with-clinical-indices-and-disease-severity
#15
Yong-Hua Gao, Juan-Juan Cui, Ling-Yun Wang, Ke-Qin Yin, Li Wang, Guo-Jun Zhang, Shao-Xia Liu
BACKGROUND: Cardiovascular disease are common co-morbidities in bronchiectasis and contribute substantially to disease burden and mortality. Brachial-ankle pulse wave velocity (baPWV), a measure of arterial stiffness, has a strong predictive value for cardiovascular event. We hypothesized that baPWV would be increased in steady-state bronchiectasis patients, and correlates with the degree of systemic inflammation and disease severity assessed with Bronchiectasis Severity Index and FACED scores...
May 9, 2018: Respiratory Research
https://www.readbyqxmd.com/read/29741564/replacement-of-dietary-saturated-fat-with-unsaturated-fats-increases-numbers-of-circulating-endothelial-progenitor-cells-and-decreases-numbers-of-microparticles-findings-from-the-randomized-controlled-dietary-intervention-and-vascular-function-divas-study
#16
Michelle Weech, Hana Altowaijri, Jordi Mayneris-Perxachs, Katerina Vafeiadou, Jacqueline Madden, Susan Todd, Kim G Jackson, Julie A Lovegrove, Parveen Yaqoob
Background: Endothelial progenitor cells (EPCs) and microparticles are emerging as novel markers of cardiovascular disease (CVD) risk, which could potentially be modified by dietary fat. We have previously shown that replacing dietary saturated fatty acids (SFAs) with monounsaturated or n-6 (ω-6) polyunsaturated fatty acids (MUFAs or PUFAs, respectively) improved lipid biomarkers, blood pressure, and markers of endothelial activation, but their effects on circulating EPCs and microparticles are unclear...
May 8, 2018: American Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/29740643/vibrational-satellites-of-c-2-s-c-3-s-and-c-4-s-microwave-spectral-taxonomy-as-a-stepping-stone-to-the-millimeter-wave-band
#17
Brett A McGuire, Marie-Aline Martin-Drumel, Kin Long Kelvin Lee, John F Stanton, Carl A Gottlieb, Michael C McCarthy
We present a microwave spectral taxonomy study of several hydrocarbon/CS2 discharge mixtures in which more than 60 distinct chemical species, their more abundant isotopic species, and/or their vibrationally excited states were detected using chirped-pulse and cavity Fourier-transform microwave spectroscopies. Taken together, in excess of 85 unique variants were detected, including several new isotopic species and more than 25 new vibrationally excited states of C2S, C3S, and C4S, which have been assigned on the basis of published vibration-rotation interaction constants for C3S, or newly calculated ones for C2S and C4S...
May 9, 2018: Physical Chemistry Chemical Physics: PCCP
https://www.readbyqxmd.com/read/29739795/effect-of-wave-reflection-and-arterial-stiffness-on-the-risk-of-development-of-hypertension-in-japanese-men
#18
Hirofumi Tomiyama, Shunsuke Komatsu, Kazuki Shiina, Chisa Matsumoto, Kazutaka Kimura, Masatsune Fujii, Lisa Takahashi, Taishiro Chikamori, Akira Yamashina
BACKGROUND: We conducted analyses of repeated-measures data to examine whether pressure wave reflection acts additively or synergistically with arterial stiffness in the pathogenesis of hypertension. METHODS AND RESULTS: In 3172 middle-aged (42±9 years) healthy Japanese men without hypertension at the study baseline, systolic and diastolic blood pressures, brachial-ankle pulse wave velocity, and radial augmentation index were measured annually during a 9-year study period...
May 8, 2018: Journal of the American Heart Association
https://www.readbyqxmd.com/read/29739314/association-between-skeletal-muscle-mass-to-visceral-fat-area-ratio-and-arterial-stiffness-in-chinese-patients-with-type-2-diabetes-mellitus
#19
Jing Xu, Xiaoyan Pan, Haili Liang, Yi Lin, Yilian Hong, Qiya Si, Feixia Shen, Xuejiang Gu
BACKGROUND: The skeletal muscle mass-to-visceral fat area ratio (SVR) has been linked to arterial stiffness in non-diabetic adults. We examined the association between the SVR and arterial stiffness in patients with type 2 diabetes mellitus (T2DM). METHODS: Patients with type 2 diabetes mellitus (252 men and 171 women) aged 40-75 years were enrolled and divided into three groups according to SVR tertiles. Arterial stiffness was measured as brachial-ankle pulse wave velocity (baPWV), with baPWV> 1800 mm/s defined as high...
May 8, 2018: BMC Cardiovascular Disorders
https://www.readbyqxmd.com/read/29729094/pulse-wave-velocity-in-the-microcirculation-reflects-both-vascular-compliance-and-resistance-insights-from-computational-approaches
#20
Qing Pan, Ruofan Wang, Bettina Reglin, Luping Fang, Jing Yan, Guolong Cai, Wolfgang M Kuebler, Axel R Pries, Gangmin Ning
OBJECTIVE: Pulse wave velocity (PWV) is the speed of pulse wave propagation through the circulatory system. Microvascular PWV (mPWV) emerges as a novel indicator of hypertension, yet it remains unclear how different vascular properties affect mPWV. We aim to identify the biomechanical determinants of mPWV. METHODS: A one-dimensional (1D) model was used to simulate PWV in a rat mesenteric microvascular network and, for comparison, in a human macrovascular arterial network...
May 5, 2018: Microcirculation: the Official Journal of the Microcirculatory Society, Inc
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