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https://www.readbyqxmd.com/read/29453470/nerve-conduction-and-heart-rate-variability-in-patients-with-hypothyroidism-at-a-tertiary-care-centre-in-eastern-nepal
#1
Shital Gupta, Rita Khadka, Dilip Thakur, Robin Maskey, K D Mehta, B H H Paudel
INTRODUCTION: Thyroid hormone effects on many organs including central and peripheral nervous systems. However, these hormones do not affect all systems/organs to a similar extent. Thus, we conducted this study to explore the effect of thyroid hormones on somatic nervous system assessed by Nerve conduction study and cardiac autonomic activity assessed by heart rate variability. METHODS: The study included newly diagnosed hypothyroid patients and healthy controls...
October 2017: JNMA; Journal of the Nepal Medical Association
https://www.readbyqxmd.com/read/29450194/avoiding-arterial-hypotension-in-preterm-neonates-ahip-a-single-center-randomised-controlled-study-investigating-simultaneous-near-infrared-spectroscopy-measurements-of-cerebral-and-peripheral-regional-tissue-oxygenation-and-dedicated-interventions
#2
Gerhard Pichler, Nina Höller, Nariae Baik-Schneditz, Bernhard Schwaberger, Lukas Mileder, Jasmin Stadler, Alexander Avian, Jasmin Pansy, Berndt Urlesberger
Introduction: Up to 50% of preterm infants admitted to intensive care units require cardiocirculatory support. The aim of the present study was to assess whether simultaneous monitoring of cerebral tissue oxygenation index (cTOI) and peripheral tissue oxygenation index (pTOI) using near-infrared spectroscopy (NIRS) in combination with dedicated intervention guidelines may help avoiding arterial hypotension and catecholamine administration in preterm neonates. Study design: Preterm neonates <37 weeks of gestation were included in a single center randomized controlled study...
2018: Frontiers in Pediatrics
https://www.readbyqxmd.com/read/29447435/asymmetric-dimethylarginine-levels-are-associated-with-augmentation-index-across-na%C3%A3-ve-untreated-patients-with-different-hypertension-phenotypes
#3
Eugenia Gkaliagkousi, Eleni Gavriilaki, Areti Triantafyllou, Barbara Nikolaidou, Panagiota Anyfanti, Nikolaos Koletsos, Anastasios Vamvakis, Konstantina Dipla, Antonios Lazaridis, Stella Douma
Asymmetric dimethylarginine (ADMA) is a robust marker of endothelial dysfunction in patients with essential hypertension. We investigated ADMA levels and their association with vascular damage in untreated hypertension. We enrolled consecutive patients with untreated, recently diagnosed hypertension and age-matched normotensive individuals. 24-hour blood pressure, central hemodynamics, and arterial stiffness were recorded. A total of 311 individuals were studied: 165 with essential hypertension, 50 with masked hypertension, 25 with white-coat hypertension, and 71 normotensive individuals...
February 15, 2018: Journal of Clinical Hypertension
https://www.readbyqxmd.com/read/29443858/measurement-of-compensatory-reserve-predicts-racial-differences-in-tolerance-to-simulated-hemorrhage-in-women
#4
Megan M Wenner, Kumba Adia Hinds, Jeffrey T Howard, Corinne D Nawn, Nina S Stachenfeld, Victor A Convertino
BACKGROUND: The measurement of Compensatory Reserve (CRM) has been established to accurately measure the body's total integrated capacity to compensate for physiological states of reduced central blood volume, and predict hemodynamic decompensation associated with inadequate tissue oxygenation. We previously demonstrated that African American (AA) women have a higher tolerance to reductions in central blood volume. Therefore, we tested the hypothesis that the CRM would identify racial differences during simulated hemorrhage, prior to the onset of traditional signs/symptoms...
February 14, 2018: Journal of Trauma and Acute Care Surgery
https://www.readbyqxmd.com/read/29443413/vascular-access-for-therapeutic-plasma-exchange
#5
REVIEW
Tina S Ipe, Marisa B Marques
Therapeutic plasma exchange is an apheresis modality in which plasma is separated from the blood cellular components ex vivo, discarded, and replaced with an isosmotic fluid (most commonly 5% albumin) to maintain appropriate oncotic pressure in the patient. Therapeutic plasma exchange is used in the treatment of many diseases and indications. The recent seventh edition of the American Society for Apheresis guidelines indicates approximately 72 diseases and 116 indications for which therapeutic plasma exchange may be effective...
February 2018: Transfusion
https://www.readbyqxmd.com/read/29443412/an-ex-vivo-comparison-of-vascular-access-devices-used-in-extracorporeal-photopheresis
#6
Jeffrey Szymanski, Priyank Shah, Marian Dynis, Donna Mansfield, Connie Hamilton, George Despotis
BACKGROUND: Central venous access devices are commonly used in extracorporeal photopheresis, but their performance has not been systematically evaluated. The primary objective of this study was to compare pressures at various flow rates for central venous access devices in an ex vivo simulation of photopheresis. STUDY DESIGN AND METHODS: Diluted, heparinized red blood cells were circulated through central access devices in series with a photopheresis system, and pressures at several flow rates were recorded...
February 2018: Transfusion
https://www.readbyqxmd.com/read/29440184/household-air-pollution-and-measures-of-blood-pressure-arterial-stiffness-and-central-haemodynamics
#7
Jill Baumgartner, Ellison Carter, James J Schauer, Majid Ezzati, Stella S Daskalopoulou, Marie-France Valois, Ming Shan, Xudong Yang
OBJECTIVE: We evaluated the exposure-response associations between personal exposure to air pollution from biomass stoves and multiple vascular and haemodynamic parameters in rural Chinese women. METHODS: We analysed the baseline information from a longitudinal study in southwestern China. Women's brachial and central blood pressure and pulse pressure, carotid-femoral pulse wave velocity and augmentation index, and their 48-hour personal exposures to fine particulate matter (PM 2...
February 9, 2018: Heart: Official Journal of the British Cardiac Society
https://www.readbyqxmd.com/read/29439683/elevated-central-venous-pressure-is-associated-with-increased-mortality-in-pediatric-septic-shock-patients
#8
Seung Jun Choi, Eun-Ju Ha, Won Kyoung Jhang, Seong Jong Park
BACKGROUND: Central venous pressure (CVP) is an important factor affecting capillary blood flow, and it is associated with poor outcomes in adult septic shock patients. However, whether a similar association exists in pediatric patients remains unclear. METHODS: We retrospectively analyzed data from patients admitted to our pediatric intensive care unit (PICU) between February 2009 and July 2015. Patients were divided into two groups-survivors and nonsurvivors-according to 28-day mortality...
February 13, 2018: BMC Pediatrics
https://www.readbyqxmd.com/read/29438454/comparative-efficacy-of-antihypertensive-agents-in-salt-sensitive-hypertensive-patients-a-network-meta-analysis
#9
Han Qi, Zheng Liu, Han Cao, Wei-Ping Sun, Wen-Juan Peng, Bin Liu, Sheng-Jie Dong, Yu-Tao Xiang, Ling Zhang
Background: Salt-sensitive hypertension (SSH) is an intermediate inherited phenotype of essential hypertension as well as being an independent risk factor for cardiovascular disease. However, effective medications for the treatment of SSH have not been clarified. This study was to compare the efficacious of different classes of antihypertensive agents combined with salt intake on the reduction of blood pressure in patients with salt-sensitive hypertension (SSH). Methods: We used sources as PubMed, EMBASE, Cochrane Library, CENTRAL, ClinicalTrials...
February 9, 2018: American Journal of Hypertension
https://www.readbyqxmd.com/read/29436195/impact-of-ambulatory-blood-pressure-on-early-cardiac-and-renal-dysfunction-in-hypertensive-patients-without-clinically-apparent-target-organ-damage
#10
Darae Kim, Chi Young Shim, Geu Ru Hong, Sungha Park, In Jeong Cho, Hyuk Jae Chang, Jong Won Ha, Namsik Chung
PURPOSE: Impaired left ventricular (LV) global longitudinal strain (GLS) and the presence of microalbuminuria indicate early cardiac and renal dysfunction. We aimed to determine the relationships among 24-h ambulatory blood pressure (BP) variables, LV GLS, and urine albumin creatinine ratio (UACR) in hypertensive patients. MATERIALS AND METHODS: A total of 130 hypertensive patients (mean age 53 years; 59 men) underwent 24-h ambulatory BP monitoring, measurements of peripheral and central BPs, and transthoracic echocardiography...
March 2018: Yonsei Medical Journal
https://www.readbyqxmd.com/read/29434010/national-prevalence-of-self-reported-coronary-heart-disease-and-chronic-stable-angina-pectoris-factor-analysis-of-the-underlying-cardiometabolic-risk-factors-in-the-fourth-round-of-the-surfncd-2011
#11
Mehrshad Abbasi, Mohamadreza Neishaboury, Jalil Koohpayehzadeh, Koorosh Etemad, Alipasha Meysamie, Fereshteh Asgari, Sina Noshad, Mohsen Afarideh, Alireza Ghajar, Morsaleh Ganji, Ali Rafei, Mostafa Mousavizadeh, Elias Khajeh, Behnam Heidari, Mohammad Saadat, Manouchehr Nakhjavani, Alireza Esteghamati
BACKGROUND: Coronary heart disease (CHD) is one of the most common causes of mortality worldwide. The national prevalence remains unclear in most of the developing countries. OBJECTIVE: This study sought to estimate national prevalence of self-reported CHD and chronic stable angina pectoris in the general adult population of Iran using data from the fourth round of the Surveillance of Risk Factors of Non-Communicable Diseases (SuRFNCD-2011) survey. METHODS: The analysis comprised data of 11,867 civilian, nonhospitalized and noninstitutionalized residents ages 6 to 70 years of age...
February 9, 2018: Global Heart
https://www.readbyqxmd.com/read/29433586/a-case-report-of-clonidine-induced-syncope-a-review-of-central-actions-of-an-old-cardiovascular-drug
#12
Alexander J Sandweiss, Christopher M Morrison, Anne Spichler, John Rozich
BACKGROUND: Clonidine is an imidazoline sympatholytic, acting on both α 2 -adrenergic and imidazoline receptors in the brainstem to induce antihypertensive and negative chronotropic effects in the vasculature and heart respectively. CASE PRESENTATION: A 69-year-old gentleman with hypertension presented to the emergency department after multiple syncopal episodes over the past 12 months. Electrocardiogram demonstrated sinus bradycardia with a heart rate of 42 beats per minute...
February 13, 2018: BMC Pharmacology & Toxicology
https://www.readbyqxmd.com/read/29433137/-the-invisibles-project-meeting-and-collaboration-of-public-health-and-volunteering-the-influenza-vaccination-experience-to-promote-the-health-of-the-socially-vulnerable-and-economically-disadvantaged-population
#13
Loris Pagano, Caterina Pizzutelli, Maria Maddalena Matarazzo, Gaia Monteleone, Damiano Pizzuti
Migration and the current European socioeconomic conditions necessitate an evaluation/assessment, as detailed as possible, of the spread of seasonal infectious diseases in order to reduce inequalities in the healthcare system. The "Scuola di Formazione in Medicina Generale" of Lazio, in collaboration with the Community of Sant'Egidio of Rome, organized an influenza/flu vaccination campaign for homeless people, migrants and the poor in order to check their health conditions and prevent the spread of the most common infectious diseases...
September 2017: Igiene e Sanità Pubblica
https://www.readbyqxmd.com/read/29430440/interaction-between-peri-operative-blood-transfusion-tidal-volume-airway-pressure-and-postoperative-ards-an-individual-patient-data-meta-analysis
#14
Ary Serpa Neto, Nicole P Juffermans, Sabrine N T Hemmes, Carmen S V Barbas, Martin Beiderlinden, Michelle Biehl, Ana Fernandez-Bustamante, Emmanuel Futier, Ognjen Gajic, Samir Jaber, Alf Kozian, Marc Licker, Wen-Qian Lin, Stavros G Memtsoudis, Dinis Reis Miranda, Pierre Moine, Domenico Paparella, Marco Ranieri, Federica Scavonetto, Thomas Schilling, Gabriele Selmo, Paolo Severgnini, Juraj Sprung, Sugantha Sundar, Daniel Talmor, Tanja Treschan, Carmen Unzueta, Toby N Weingarten, Esther K Wolthuis, Hermann Wrigge, Marcelo Gama de Abreu, Paolo Pelosi, Marcus J Schultz
Background: Transfusion of blood products and mechanical ventilation with injurious settings are considered risk factors for postoperative lung injury in surgical Patients. Methods: A systematic review and individual patient data meta-analysis was done to determine the independent effects of peri-operative transfusion of blood products, intra-operative tidal volume and airway pressure in adult patients undergoing mechanical ventilation for general surgery, as well as their interactions on the occurrence of postoperative acute respiratory distress syndrome (ARDS)...
January 2018: Annals of Translational Medicine
https://www.readbyqxmd.com/read/29428622/targeted-increase-in-pulmonary-blood-flow-in-a-bidirectional-glenn-circulation
#15
Samuel L Casella, Aditya Kaza, Pedro Del Nido, James E Lock, Audrey Marshall
Objective In patients with a Glenn shunt and unilateral pulmonary vascular abnormalities, supplemental pulmonary blood flow may improve antegrade flow in the target lung and may permit eventual Fontan completion, while mitigating the risks of uncontrolled additional flow to the contralateral lung. We attempted this by inserting a small aortopulmonary shunt into the affected pulmonary artery and banding the central pulmonary artery. .Methods We performed a retrospective review of all patients who underwent this procedure from 2000-2015...
February 8, 2018: Seminars in Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/29425776/the-effects-of-hemoglobin-glutamer-200-and-ino-on-pulmonary-vascular-tone-and-arterial-oxygenation-in-an-experimental-acute-respiratory-distress-syndrome
#16
Maria Theresa Voelker, Andreas Bergmann, Thilo Busch, Nora Jahn, Sven Laudi, Katharina Noreikat, Philipp Simon, Sven Bercker
INTRODUCTION: Hemoglobin-based oxygen carriers (HBOC) have been developed as an alternative to blood transfusions. Their nitric-oxide-scavenging properties HBOC also induce vasoconstriction. In acute lung injury, an excess of nitric oxide results in a general vasodilation, reducing oxygenation by impairing the hypoxic pulmonary vasoconstriction. Inhaled nitric oxide (iNO) is used to correct the ventilation perfusion mismatch. We hypothesized that the additional use of HBOC might increase this effect...
February 6, 2018: Pulmonary Pharmacology & Therapeutics
https://www.readbyqxmd.com/read/29425479/differential-risk-of-hypertension-among-lean-and-nonlean-rural-subjects-in-relation-to-decadal-changes-in-anthropometry
#17
Sayali S Deshpande-Joshi, Shobha Rao
OBJECTIVE: Assessing risk of hypertension in relation to decadal changes in anthropometry among cohort of young rural Indian men. METHODS: Subjects (n = 140) were measured in 2005 and 2015 for blood pressure, body mass index (BMI), body fat (BF), waist circumference (WC), waist-to-hip ratio (WHR), and additionally for visceral fat (VF) at follow-up. RESULTS: Decadal changes showed significant (p < 0.001) increase in mean anthropometric measures and in prevalence of overall obesity (BMI ≥25 kg/m2) from 3...
February 9, 2018: Journal of the American College of Nutrition
https://www.readbyqxmd.com/read/29424010/excess-weight-in-children-and-adolescents-is-associated-with-altered-subendocardial-blood-supply-among-girls-but-not-boys
#18
Divanei Zaniqueli, Rafael O Alvim, Marcelo P Baldo, Sara G Luiz, Roberto Sá Cunha, José G Mill
Subendocardial viability ratio (SEVR) is a reliable index of myocardial supply-workload balance. This study sought to investigate whether overweight/obese children and adolescents have altered SEVR and to identify which are the associated factors. This cross-sectional study involved 789 individuals. Central haemodynamic was measured by radial applanation tonometry. Diastolic time was shorter (496 ± 122 vs. 537 ± 140 ms, p= 0.014) and diastolic pressure-time index was lower (2681 ± 412 vs. 2814 ± 423 mmHg x s, p=0...
February 9, 2018: Clinical and Experimental Pharmacology & Physiology
https://www.readbyqxmd.com/read/29422868/relationship-between-aortic-compliance-and-impact-of-cerebral-blood-flow-fluctuation-to-dynamic-orthostatic-challenge-in-endurance-athletes
#19
Tsubasa Tomoto, Tomoko Imai, Shigehiko Ogoh, Seiji Maeda, Jun Sugawara
Aorta effectively buffers cardiac pulsatile fluctuation generated from the left ventricular (LV) which could be a mechanical force to high blood flow and low-resistance end-organs such as the brain. A dynamic orthostatic challenge may evoke substantial cardiac pulsatile fluctuation via the transient increases in venous return and stroke volume (SV). Particularly, this response may be greater in endurance-trained athletes (ET) who exhibit LV eccentric remodeling. The aim of this study was to determine the contribution of aortic compliance to the response of cerebral blood flow fluctuation to dynamic orthostatic challenge in ET and age-matched sedentary (SED) young healthy men...
2018: Frontiers in Physiology
https://www.readbyqxmd.com/read/29420594/effects-of-metabolic-syndrome-on-bone-mineral-density-histomorphometry-and-remodelling-markers-in-male-rats
#20
Sok Kuan Wong, Kok-Yong Chin, Farihah Hj Suhaimi, Fairus Ahmad, Soelaiman Ima-Nirwana
This study aimed to evaluate the effects of metabolic syndrome (MetS) induced by high-carbohydrate high-fat (HCHF) diet on bone mineral density (BMD), histomorphometry and remodelling markers in male rats. Twelve male Wistar rats aged 12 weeks old were randomized into two groups. The normal group was given standard rat chow while the HCHF group was given HCHF diet to induce MetS. Abdominal circumference, blood glucose, blood pressure, and lipid profile were measured for the confirmation of MetS. Bone mineral density, histomorphometry and remodelling markers were evaluated for the confirmation of bone loss...
2018: PloS One
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