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Dental Biomaterials

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https://www.readbyqxmd.com/read/28301307/silicon-nitride-si3n4-implants-the-future-of-dental-implantology
#1
Zahi Badran, Xavier Struillou, Francis J Hughes, Assem Soueidan, Alain Hoornaert, Mark Ide
For decades titanium has been the preferred material for dental implant fabrication, with mechanical and biological performance resulting in high clinical success rates. Tshese have been further enhanced by incremental development of surface modifications aimed at improving speed and degree of osseointegration and resulting in enhanced clinical treatment options and outcomes. However, increasing demand for metal-free dental restorations has also led to the development of ceramic-based dental implants such as zirconia...
March 16, 2017: Journal of Oral Implantology
https://www.readbyqxmd.com/read/28291861/bone-regeneration-using-adipose-derived-stem-cells-with-fibronectin-in-dehiscence-type-defects-associated-with-dental-implants-an-experimental-study-in-a-dog-model
#2
Maria Àngels Sánchez-Garcés, Joaquín Alvira-González, Claudia Müller Sánchez, Joan R Barbany Cairó, Manuel Reina Del Pozo, Cosme Gay-Escoda
PURPOSE: To determine the bone regeneration potential of a ceramic biomaterial coated with fibronectin and adipose-derived stem cells covered in three-wall critical-size defects associated with dental implants. MATERIALS AND METHODS: In a total of 18 dogs, four dehiscence-type and critical-size defects were created surgically in the edentulous alveolar ridge with the simultaneous placement of dental implants. Defects were randomly regenerated using biomaterials coated with particulate ß-tricalcium phosphate (β-TCP), β-TCP with fibronectin (Fn) (β-TCP-Fn), and β-TCP with a combination of Fn and autologous adipose-derived stem cells (ADSCs) (β-TCP-Fn-ADSCs), leaving one defect as the control...
March 2017: International Journal of Oral & Maxillofacial Implants
https://www.readbyqxmd.com/read/28285545/to-reduce-the-maximum-stress-and-the-stress-shielding-effect-around-a-dental-implant-bone-interface-using-radial-functionally-graded-biomaterials
#3
H Asgharzadeh Shirazi, M R Ayatollahi, A Asnafi
In a dental implant system, the value of stress and its distribution plays a pivotal role on the strength, durability and life of the implant-bone system. A typical implant consists of a Titanium core and a thin layer of biocompatible material such as the hydroxyapatite. This coating has a wide range of clinical applications in orthopedics and dentistry due to its biocompatibility and bioactivity characteristics. Low bonding strength and sudden variation of mechanical properties between the coating and the metallic layers are the main disadvantages of such common implants...
March 13, 2017: Computer Methods in Biomechanics and Biomedical Engineering
https://www.readbyqxmd.com/read/28281315/silicates-in-orthopaedics-and-bone-tissue-engineering-materials
#4
REVIEW
Xianfeng Zhou, Nianli Zhang, Steven Mankoci, Nita Sahai
Following the success of silicate-based glasses as bioactive materials, silicates are believed to play important roles in promoting bone formation and have therefore been considered to provide a hydroxyapatite surface layer capable of binding to bone as well as potentially being a pro-osteoinductive factor. Natural silicate minerals and silicate-substituted hydroxyapatites are also being actively investigated as orthopaedic bone and dental biomaterials for application in tissue engineering. However, the mechanisms for the proposed roles of silicate in these materials have not been fully understood and are controversial...
March 9, 2017: Journal of Biomedical Materials Research. Part A
https://www.readbyqxmd.com/read/28274193/a-peptide-based-biological-coating-for-enhanced-corrosion-resistance-of-titanium-alloy-biomaterials-in-chloride-containing-fluids
#5
Noah Muruve, Yuanchao Feng, Jaye Platnich, Daniel Hassett, Randall Irvin, Daniel Muruve, Frank Cheng
Titanium alloys are common materials in the manufacturing of dental and orthopedic implants. Although these materials exhibit excellent biocompatibility, corrosion in response to biological fluids can impact prosthesis performance and longevity. In this work, a PEGylated metal binding peptide (D-K122-4-PEG), derived from bacteria Pseudomonas aeruginosa, was applied on a titanium (Ti) alloy, and the corrosion resistance of the coated alloy specimen was investigated in simulated chloride-containing physiological fluids by electrochemical impedance spectroscopy and micro-electrochemical measurements, surface characterization, and biocompatibility testing...
March 2017: Journal of Biomaterials Applications
https://www.readbyqxmd.com/read/28261524/a-comparison-of-different-compressive-forces-on-graft-materials-during-alveolar-ridge-preservation
#6
In-Woo Cho, Jung-Chul Park, Hyun-Seung Shin
PURPOSE: Following tooth extraction, alveolar ridge preservation (ARP) can maintain the dimensions of ridge height and width. Although previous studies have demonstrated the effects of ARP, few if any studies have investigated the compressive force applied during grafting. The aim of this study was to determine the effects of different compressive forces on the graft materials during ARP. METHODS: After tooth extraction, sockets were filled with deproteinized bovine bone mineral with 10% porcine collagen and covered by a resorbable collagen membrane in a double-layered fashion...
February 2017: Journal of Periodontal & Implant Science
https://www.readbyqxmd.com/read/28251794/augmentation-of-severly-resorbed-alveolar-crests-with-bovine-bone-blocks-a-human-histology-pilot-study
#7
Christer Slotte, Ulf Nannmark
BACKGROUND: Allo-/xenogenic bone blocks are used to treat bone defects. Few human histologic studies are found on their integration and capacity to augment new bone. PURPOSE: To study incorporation and stability of collagenated bovine bone blocks (CBB). Short term effects, histology, and morphometry on biopsy specimens are presented. MATERIALS AND METHODS: Nine patients exhibiting extremely narrow alveolar ridges had CBB adapted and fixed to the recipient bone and covered with collagen barriers...
March 1, 2017: Clinical Implant Dentistry and related Research
https://www.readbyqxmd.com/read/28250998/a-novel-procedure-for-the-immediate-reconstruction-of-severely-resorbed-alveolar-sockets-for-advanced-periodontal-disease
#8
Mario Aimetti, Valeria Manavella, Luca Cricenti, Federica Romano
Background. Several clinical techniques and a variety of biomaterials have been introduced over the years in an effort to overcome bone remodeling and resorption after tooth extraction. However, the predictability of these procedures in sockets with severely resorbed buccal/lingual plate due to periodontal disease is still unknown. Case Description. A patient with advanced periodontitis underwent extraction of upper right lateral and central incisors. The central incisor exhibited complete buccal bone plate loss and a 9 mm vertical bone deficiency on its palatal side...
2017: Case Reports in Dentistry
https://www.readbyqxmd.com/read/28246094/bactericidal-and-antimicrobial-effects-of-pure-titanium-and-titanium-alloy-treated-with-short-term-low-energy-uv-irradiation
#9
T Itabashi, K Narita, A Ono, K Wada, T Tanaka, G Kumagai, R Yamauchi, A Nakane, Y Ishibashi
OBJECTIVES: The surface of pure titanium (Ti) shows decreased histocompatibility over time; this phenomenon is known as biological ageing. UV irradiation enables the reversal of biological ageing through photofunctionalisation, a physicochemical alteration of the titanium surface. Ti implants are sterilised by UV irradiation in dental surgery. However, orthopaedic biomaterials are usually composed of the alloy Ti6Al4V, for which the antibacterial effects of UV irradiation are unconfirmed...
February 2017: Bone & Joint Research
https://www.readbyqxmd.com/read/28238010/verification-of-implant-surface-modification-by-a-novel-processing-method
#10
COMPARATIVE STUDY
Yoshiki Okada, Nobuhiro Abe, Noriyuki Hisamori, Toshiaki Kaneeda, Shigeaki Moriyama, Hitoshi Ohmori, Masayoshi Mizutani, Hiroyuki Yanai, Yoshio Nakashima, Yusuke Yokoyama, Toshifumi Ozaki
Metals have been used clinically as biomaterials, especially in the orthopaedic and dental fields. Metals used as implants wear at contact surfaces, producing metal particles and metal ions that may be harmful. Newly developed metal implants and methods of implant surface modification are currently under scrutiny. We evaluated the use of electrolytic in-process dressing (ELID) as a surface finishing method for metal implants. Metal implants processed using the ELID method (ELID group) or not processed (Non-ELID group) were inserted surgically into rabbit femurs...
February 2017: Acta Medica Okayama
https://www.readbyqxmd.com/read/28236437/biocompatibility-of-biomaterials-lessons-learned-and-considerations-for-the-design-of-novel-materials
#11
REVIEW
Gottfried Schmalz, Kerstin M Galler
OBJECTIVES: Biocompatibility of dental materials has gained increasing interest during recent decades. Meanwhile, legal regulations and standard test procedures are available to evaluate biocompatibility. Herein, these developments will be exemplarily outlined and some considerations for the development of novel materials will be provided. METHODS: Different aspects including test selection, release of substances, barriers, tissue healing, antibacterial substances, nanoparticles and environmental aspects will be covered...
February 21, 2017: Dental Materials: Official Publication of the Academy of Dental Materials
https://www.readbyqxmd.com/read/28230598/analysis-of-the-adherence-of-dental-pulp-stem-cells-on-two-dimensional-and-three-dimensional-silk-fibroin-based-biomaterials-applications-in-regenerative-dentistry
#12
María Pilar Pecci-Lloret, Mar Vera-Sánchez, Salvador Aznar-Cervantes, David García-Bernal, Ricardo Oñate Sánchez, Miguel Ramón Pecci-Lloret, José María Moraleda, José Luis Cenis, Francisco Javier Rodríguez-Lozano
Among various biomaterials used as scaffolds in tissue engineering, silk fibroin is a highly attractive material. A scaffold should be biocompatible and nontoxic, with optimal physical features and mechanical properties. For this reason, tissue-engineering approaches in regenerative medicine have focused on investigating the biocompatibility of possible biomaterials by analyzing cell-scaffold interaction properties. The aim of the present study was to examine the biocompatibility of silk fibroin as a film (two-dimensional [2D]) and a scaffold (three-dimensional [3D]) after being cellularized with human dental pulp stem cells (hDPSCs)...
February 22, 2017: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/28222907/fatigue-testing-of-biomaterials-and-their-interfaces
#13
Dwayne Arola
OBJECTIVE: The objective of this article is to describe the importance of fatigue to the success of restorative dentistry, with emphasis on the methods for evaluating the fatigue properties of materials in this field, and the durability of their bonded interfaces. METHODS: The stress-life fatigue and fatigue crack growth approaches for evaluating the fatigue resistance of dental biomaterials are introduced. Emphasis is placed on in vitro studies of the hard tissue foundation, restorative materials and their bonded interfaces...
February 17, 2017: Dental Materials: Official Publication of the Academy of Dental Materials
https://www.readbyqxmd.com/read/28218482/osteoblastic-differentiation-of-periodontal-ligament-stem-cells-on-non-stoichiometric-calcium-phosphate-and-titanium-surfaces
#14
Lewis Winning, Leanne Robinson, Adrian R Boyd, Ikhlas A El Karim, Fionnuala T Lundy, Brian J Meenan
Bioactive materials offer particular clinical benefits in the field of dental implantology, where differentiation of stem cells towards an osteoblastic lineage is required for osseointegration and appropriate function of implants in vivo. The aim of this study was to evaluate the osteoblastic response of Stro-1 +ve periodontal ligament stem cells (PDLSCs) to three well-characterized biomaterial surfaces: an abraded titanium surface (cpTi) control; a polycrystalline titanium surface, with both micro and nanotopography produced by radio frequency magnetron sputtering (TiTi); and the same surface incorporating a sputter deposited calcium phosphate coating (CaP-TiTi)...
February 20, 2017: Journal of Biomedical Materials Research. Part A
https://www.readbyqxmd.com/read/28215503/biomaterial-shell-bending-with-3d-printed-templates-in-vertical-and-alveolar-ridge-augmentation-a-technical-note
#15
Florian G Draenert, Florian Gebhart, Gergo Mitov, Andreas Neff
OBJECTIVES: Alveolar ridge and vertical augmentations are challenging procedures in dental implantology. Even material blocks with an interconnecting porous system are never completely resorbed. Shell techniques combined with autologous bone chips are therefore the gold standard. Using biopolymers for these techniques is well documented. We applied three-dimensional (3-D) techniques to create an individualized bending model for the adjustment of a plane biopolymer membrane made of polylactide...
January 4, 2017: Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology
https://www.readbyqxmd.com/read/28207942/effect-of-ridge-preservation-for-early-implant-placement-is-there-a-need-to-remove-the-biomaterial
#16
Daniel S Thoma, Nadja Naenni, Goran I Benic, Fernando Munoz, Christoph H F Hämmerle, Ronald E Jung
AIM: to assess i) bone regeneration around implants placed early in sites with or without ridge preservation and i) if the bone substitute material (DBBM-C) has to be removed at implant placement MATERIALS AND METHODS: In eight beagle dogs, three sites were randomly assigned to ridge preservation (DBBM-C plus collagen matrix (CMX)) (two sites; RP) or spontaneous healing (1 site; SH). Four weeks later, in one of the RP sites, dental implants were placed without removing the DBBM-C (RP1), whereas in RP2 and SH sites all non-integrated DBBM-C and/or granulation tissue was removed before implant placement and concomitant GBR...
February 16, 2017: Journal of Clinical Periodontology
https://www.readbyqxmd.com/read/28199081/correction-to-a-mesoporous-silica-biomaterial-for-dental-biomimetic-crystallization
#17
Yu-Chih Chiang, Hong-Ping Lin, Hao-Hueng Chang, Ya-Wen Cheng, Hsin-Yen Tang, Wei-Ching Yen, Po-Yen Lin, Kei-Wen Chang, Chun-Pin Lin
No abstract text is available yet for this article.
February 28, 2017: ACS Nano
https://www.readbyqxmd.com/read/28160669/effect-of-sex-hormone-levels-sex-body-mass-index-and-other-host-factors-on-human-craniofacial-bone-regeneration-with-bioactive-tricalcium-phosphate-grafts
#18
Christine Knabe, Aynur Mele, Peter Herbert Kann, Barbara Peleska, Doaa Adel-Khattab, Harald Renz, Alexander Reuss, Marc Bohner, Michael Stiller
Little is known regarding the associations between sex-hormone levels, sex, body mass index (BMI), age, other host factors and biomaterial stimulated bone regeneration in the human craniofacial skeleton. The aim of this study was to elucidate the associations between these factors and bone formation after sinus floor augmentation procedures (SFA) utilizing a bioactive tricalcium phosphate (TCP) bone grafting material. We conducted a prospective study in a human population in which 60 male and 60 female participants underwent SFA and dental implant placement using a staged approach...
January 28, 2017: Biomaterials
https://www.readbyqxmd.com/read/28157689/differential-mineralization-of-human-dental-pulp-stem-cells-on-diverse-polymers
#19
Christian Apel, Patricia Buttler, Jochen Salber, Anandhan Dhanasingh, Sabine Neuss
In tissue engineering, biomaterials are used as scaffolds for spatial distribution of specific cell types. Biomaterials can potentially influence cell proliferation and extracellular matrix formation, both in positive and negative ways. The aim of the present study was to investigate and compare mineralized matrix production of human dental pulp stem cells (DPSC), cultured on 17 different well-characterized polymers. Osteogenic differentiation of DPSC was induced for 21 days on biomaterials using dexamethasone, L-ascorbic-acid-2-phosphate, and sodium β-glycerophosphate...
February 3, 2017: Biomedizinische Technik. Biomedical Engineering
https://www.readbyqxmd.com/read/28149193/sheep-as-an-experimental-model-for-biomaterial-implant-evaluation
#20
Suelen Cristina Sartoretto, Marcelo José Uzeda, Fúlvio Borges Miguel, Jhonathan Raphaell Nascimento, Fabio Ascoli, Mônica Diuana Calasans-Maia
OBJECTIVE: Based on a literature review and on our own experience, this study proposes sheep as an experimental model to evaluate the bioactive capacity of bone substitute biomaterials, dental implant systems and orthopedics devices. The literature review covered relevant databases available on the Internet from 1990 until to date, and was supplemented by our own experience. METHODS: For its resemblance in size and weight to humans, sheep are quite suitable for use as an experimental model...
September 2016: Acta Ortopedica Brasileira
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