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Diego Sangiorgi, Valentina Perrone, Stefano Buda, Lucio Boglione, Giuseppe Cariti, Cinira Lefevre, Carmela Nappi, Luca Degli Esposti
OBJECTIVE: The objectives of this study were to estimate the prevalence of Hepatitis C among six Italian Local Health Units (LHUs), to describe patient and antiviral drug characteristics, and to estimate the health care consumption rates and related costs for the management of patients affected by hepatitis C virus (HCV) infection by using data from routine clinical practice. METHODS: We conducted a retrospective study using administrative databases of six Italian LHUs...
2017: ClinicoEconomics and Outcomes Research: CEOR
Benedetta Contoli, Patrizia Carrieri, Maria Masocco, Luana Penna, Alberto Perra
BACKGROUND: Italy is particularly concerned by population ageing. The costs for society are substantial. In this context a national, representative surveillance system, Passi D'Argento (PDA), was implemented in 2009 to monitor "active aging" and health status in people aged over 64 and to develop preventive health programs to reduce frailty. METHODS/DESIGN: PDA recruited a representative sample of 24 129 individuals (March 2012-January 2013) aged over 64 who were interviewed by trained staff using a standardized questionnaire...
October 2016: Annali Dell'Istituto Superiore di Sanità
Laura Lauria, Angela Spinelli, Michele Grandolfo
INTRODUCTION: Breastfeeding is widely recommended. Updated data are needed to assess its prevalence and the effectiveness of interventions. Breastfeeding practices in Italy need to be promoted and monitored with updated and standard data The objective of this study is to provide estimates of the prevalence of breastfeeding and exclusively breastfeeding and to identify factors that may be modified to improve them. MATERIALS AND METHODS: Two population-based follow-up surveys were conducted to evaluate the quality of maternal care in 25 Local Health Units (LHUs) in Italy during 2008-2011...
July 2016: Annali Dell'Istituto Superiore di Sanità
Irene Bellini, Antonino Nastasi, Sara Boccalini
In Tuscany (Central Italy), the average annual notification rate of tuberculosis (TB) in the years 2007-2012 was 7.5-9.8 per 100,000 people, with the Local Health Unit of Prato (LHU4) showing the highest rate compared to the other regional area. Therefore, in order to reduce the burden of TB, foreign newborns in the LHU4 are being given the Bacillus Calmette-Guérin (BCG) vaccine since 2000. The aim of this study is to assess the impact of BCG vaccination in Prato, in terms of TB-related hospitalizations and costs...
September 2016: Human Vaccines & Immunotherapeutics
Ilaria Marcianò, Ylenia Ingrasciotta, Francesco Giorgianni, Jenny Bolcato, Alessandro Chinellato, Roberta Pirolo, Annalisa Di Giorgio, Sonia Manna, Valentina Ientile, Rosa Gini, Mariacarmela Santarpia, Armando A Genazzani, Ilaria Uomo, Maurizio Pastorello, Sebastiano W Pollina Addario, Salvatore Scondotto, Pasquale Cananzi, Roberto Da Cas, Giuseppe Traversa, Mariangela Rossi, Laura Sottosanti, Achille P Caputi, Gianluca Trifirò
BACKGROUND: Granulocyte colony-stimulating factors (G-CSFs) are biological products for which the main indication of use is chemotherapy-induced neutropenia. Biosimilars of G-CSFs have been available in Europe since 2007. OBJECTIVE: The objective of this study was to investigate the prescribing pattern of G-CSFs in five Italian centres using different healthcare policy interventions to promote the use of biosimilars in routine care. METHODS: This retrospective, population-based drug utilization study was conducted during the years 2009-2014 using the administrative databases of the Caserta, Treviso and Palermo Local Health Units (LHUs) and the Tuscany and Umbria regions...
August 2016: BioDrugs: Clinical Immunotherapeutics, Biopharmaceuticals and Gene Therapy
Stefano Calciolari, Stefania Ilinca
In recent decades, consensus has grown on the need to organize health systems around the concept of care integration to better confront the challenges associated with demographic trends and financial sustainability. However, care integration remains an imprecise umbrella term in both the academic and policy arenas. In addition, little substantive knowledge exists on the success factors for integration initiatives. We propose a composite measure of care integration and a conceptual framework suggesting its relationships with three types of antecedents: contextual, cultural, and organizational factors...
January 2016: Health Policy
Zhixing Sun, Lan Zhu, Huiying Hu, Jinghe Lang, Honghui Shi, Xiaoming Gong
OBJECTIVE: To evaluate anatomic and sexual outcomes among young women with severe pelvic organ prolapse undergoing combined trachelectomy and laparoscopic high uterosacral ligament suspension (LHUS). METHODS: In a prospective study in Beijing, China, patients (aged ≤50 years) with pelvic organ prolapse of stage III or higher according to the Pelvic Organ Prolapse Quantification (POP-Q) were enrolled between November 2007 and August 2011. After combined trachelectomy and LHUS, patients were followed up at 6 weeks, 6 months, 12 months, and yearly thereafter...
February 2016: International Journal of Gynaecology and Obstetrics
L Degli Esposti, D Sangiorgi, S Buda, E Crovato, C Nappi, C Lefevre
No abstract text is available yet for this article.
November 2015: Value in Health: the Journal of the International Society for Pharmacoeconomics and Outcomes Research
L Degli Esposti, D Sangiorgi, S Buda, E Crovato, C Cerra
No abstract text is available yet for this article.
November 2015: Value in Health: the Journal of the International Society for Pharmacoeconomics and Outcomes Research
Ylenia Ingrasciotta, Francesco Giorgianni, Jenny Bolcato, Alessandro Chinellato, Roberta Pirolo, Daniele Ugo Tari, Chiara Troncone, Andrea Fontana, Valentina Ientile, Rosa Gini, Domenico Santoro, Mariacarmela Santarpia, Armando Genazzani, Ilaria Uomo, Maurizio Pastorello, Walter Sebastiano Pollina Addario, Salvatore Scondotto, Pasquale Cananzi, Achille Patrizio Caputi, Gianluca Trifirò
PURPOSE: To explore the prescription patterns of erythropoiesis-stimulating agents (ESAs) in four large Italian geographic areas, where different health policy interventions to promote biosimilar use in routine care are undertaken. METHODS: A retrospective drug utilization study was conducted during the years 2009-2013. The data sources were the administrative databases of the Tuscany region and of the Caserta, Palermo, and Treviso Local Health Units (LHUs). The characteristics, prevalence, and switching patterns of different ESAs (biosimilars and reference products), stratified by indication for use, were calculated over time and across centers...
August 2015: BioDrugs: Clinical Immunotherapeutics, Biopharmaceuticals and Gene Therapy
M Padoan, D Ferrante, G Pretti, C Magnani
BACKGROUND: Breast cancer is the most common cancer and the leading cause of cancer death in women. Early detection is essential to reduce cancer mortality. Studying participation in an organised breast cancer screening program is important in order to evaluate the program effectiveness. Breast screening both enables minimally invasive breast surgery and reduces cause-specific mortality. METHODS: The main objective of this study was to evaluate, through the use of a questionnaire, the influence of socio-economic characteristics (age, education, occupational status, participation in other screening programs etc...
November 2014: Annali di Igiene: Medicina Preventiva e di Comunità
Yi-Hsiang Chao, Jyun-Fong Jheng, Jhong-Sian Wu, Kuan-Yi Wu, Hsih-Hao Peng, Ming-Chi Tsai, Chin-Li Wang, Yen-Ni Hsiao, Chien-Lung Wang, Ching-Yao Lin, Chain-Shu Hsu
A copolymerization strategy is developed to utilize porphyrin as a complementary light-harvesting unit (LHU) in D-A polymers. For polymer solar cells (PSCs), the presence of LHUs increases the short-circuit current density (Jsc ) without sacrificing the open-circuit voltage (Voc ) and fill factor (FF). Up to 8.0% power conversion efficiency (PCE) is delivered by PPor-2:PC71 BM single-junction PSCs. A PCE of 8.6% is achieved when a C-PCBSD cathodic interlayer is introduced.
August 13, 2014: Advanced Materials
Sandro Baldissera, Gianluigi Ferrante, Elisa Quarchioni, Valentina Minardi, Valentina Possenti, Giuliano Carrozzi, Maria Masocco, Stefania Salmaso
PURPOSE: Field substitution of nonrespondents can be used to maintain the planned sample size and structure in surveys but may introduce additional bias. Sample weighting is suggested as the preferable alternative; however, limited empirical evidence exists comparing the two methods. We wanted to assess the impact of substitution on surveillance results using data from Progressi delle Aziende Sanitarie per la Salute in Italia-Progress by Local Health Units towards a Healthier Italy (PASSI)...
April 2014: Annals of Epidemiology
Maria Rosa Pelizzo, Domenico Rubello, Chiara Bernardi, Giancarlo Gemo, Loris Bertazza, Elena Schievano, Ugo Fedeli
AIM: To investigate the effects of changing surgical practices on thyroid cancer incidence in the Veneto Region (North-Eastern Italy). METHODS: Hospital discharge records of the period 2000-2010 were analyzed to detect trends in thyroid surgery rates by type of surgery and diagnosis. The association between surgery rates for benign and malignant diseases across the 21 Local Health Units (LHUs) was assessed by Poisson regression. In a second step, clinical and pathological charts of the year 2010 were retrieved from the larger regional surgical center...
February 2014: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
D Piovani, A Clavenna, M Sequi, M Cartabia, A Bortolotti, I Fortino, L Merlino, M Bonati
WHAT IS KNOWN AND OBJECTIVE: Italian children receive a high number of antibiotic prescriptions, and the use of second-choice antibiotics is common. A few studies in other countries have demonstrated that the implementation of international guidelines for the most common paediatric diseases may reduce the associated costs. A cost analysis of the expenditure for antibiotic prescriptions in outpatient children in the Lombardy region (Italy) and for each of the region's local health units (LHUs) was performed using a pharmacoepidemiological approach...
October 2013: Journal of Clinical Pharmacy and Therapeutics
Daniele Piovani, Antonio Clavenna, Maurizio Bonati
BACKGROUND: Large differences exist in the prevalence rate of drugs prescribed to children and adolescents between and within countries. The aim of this study was to evaluate child and adolescent drug prescription patterns in Italy in an extra-hospital setting at the regional and Local Health Unit (LHU) levels. METHODS: Data sources were three regional prescription databases. Data concerning the year 2008 were evaluated. A total of 3.3 million children and adolescents were included...
2013: BMC Pediatrics
Maurizio Leoni, Radha Sadacharan, Daniel Louis, Fabio Falcini, Carol Rabinowitz, Luca Cisbani, Rossana De Palma, Elaine Yuen, Roberto Grilli
AIMS AND BACKGROUND: This study examines the patterns of follow-up care for breast cancer survivors in one region in Italy. METHODS AND STUDY DESIGN: This retrospective analysis included 10,024 surgically treated women, with incident cases of breast cancer in the years 2002-2005 who were alive 18 months after their incidence date. Rates of use of follow-up mammograms, abdominal echogram, bone scans and chest x-rays were estimated from administrative data and compared by Local Health Unit (LHU) of residence...
January 2013: Tumori
Cristina Giambi, Serena Donati, Francesca Carozzi, Stefania Salmaso, Silvia Declich, Marta L Ciofi degli Atti, Guglielmo Ronco, Maria P Alibrandi, Silvia Brezzi, Natalina Collina, Daniela Franchi, Amedeo Lattanzi, Maria C Minna, Roberto Nannini, Elena Barretta, Elena Burroni, Anna Gillio-Tos, Vincenzo Macallini, Paola Pierotti, Antonino Bella
BACKGROUND: Pre-vaccination information on HPV type-specific prevalence in target populations is essential for designing and monitoring immunization strategies for cervical cancer (CC) prevention. Data on HPV prevalence in Italy are available for women over the age of 24 years, target of the population-based CC screening programmes; while data of HPV prevalence in younger ages are very limited. The present study enrolled Italian women aged 18-26 years in order to assess the prevalence and distribution of high-risk (HR) HPV types...
2013: BMC Infectious Diseases
M Vanzetta, E Vellone, M G De Marinis, I Cavicchi, R Alvaro
INTRODUCTION: In most countries where Internet is widely used the number of people surfing the web for healthcare information equals (and in some countries is more than) the number of people looking for healthcare assistance. More and more often, all over the world, Internet is integrated by advanced healthcare systems as a cornerstone of their e-health infrastructure, to meet citizens' needs for health information. Therefore, information plays a key role in the relationship between healthcare providers and citizenship...
November 2012: Annali di Igiene: Medicina Preventiva e di Comunità
Laura Lauria, Anna Lamberti, Michele Grandolfo
Data for this study were obtained from a population-based follow-up study in 25 Italian Local Health Units (LHUs) to evaluate pregnancy, delivery, and postpartum care in Italy. A sample of 3534 women was recruited and interviewed within a few days of their giving birth and at 3, 6, and 12 months after delivery, by trained interviewers using questionnaires. The objective of the study was to evaluate changes in smoking behaviour from one interview to the next. Of 2546 women who completed the follow-up, smoking prevalences before and during pregnancy were 21...
2012: TheScientificWorldJournal
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