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https://www.readbyqxmd.com/read/28719958/a-case-of-furuncular-myiasis-due-to-cordylobia-anthropophaga-in-a-korean-traveler-returning-from-uganda
#1
Su-Min Song, Shin-Woo Kim, Youn-Kyoung Goo, Yeonchul Hong, Meesun Ock, Hee-Jae Cha, Dong-Il Chung
A fly larva was recovered from a boil-like lesion on the left leg of a 33-year-old male on 21 November 2016. He has worked in an endemic area of myiasis, Uganda, for 8 months and returned to Korea on 11 November 2016. The larva was identified as Cordylobia anthropophaga by morphological features, including the body shape, size, anterior end, posterior spiracles, and pattern of spines on the body. Subsequent 28S rRNA gene sequencing showed 99.9% similarity (916/917 bp) with the partial 28S rRNA gene of C. anthropophaga...
June 2017: Korean Journal of Parasitology
https://www.readbyqxmd.com/read/28719750/electrostatic-interaction-assisted-construction-of-3d-networks-of-manganese-dioxide-nanosheets-for-flexible-high-performance-solid-state-asymmetric-supercapacitors
#2
Na Liu, Yan Li Su, Zhiqiang Wang, Zhen Wang, Jinsong Xia, Yong Chen, Zhigang Zhao, Qingwen Li, Fengxia Geng
A three-dimensional (3D) macroscopic network of manganese oxide MnO2 sheets was firstly synthesized by an easily scalable solution approach, grafting the negatively charged surfaces of the MnO2 sheets with an aniline monomer by electrostatic interactions followed by a quick chemical oxidizing polymerization reaction. The obtained structure possessed MnO2 sheets interconnected with polyaniline chains, producing a 3D monolith rich of mesopores. The MnO2 sheets had almost all their reactive centers exposed on the electrode surface, combining with the electron transport highways provided by polyaniline and the shortened diffusion paths provided by the porous structure, the deliberately designed electrode achieved excellent capacitance of 762 F g-1 at a current of 1 A g-1 and cycling performance with a capacity retention of 90% over 8000 cycles...
July 18, 2017: ACS Nano
https://www.readbyqxmd.com/read/28719602/prehospital-immune-responses-and-development-of-multiple-organ-dysfunction-syndrome-following-traumatic-injury-a-prospective-cohort-study
#3
Jon Hazeldine, David N Naumann, Emma Toman, David Davies, Jonathan R B Bishop, Zhangjie Su, Peter Hampson, Robert J Dinsdale, Nicholas Crombie, Niharika Arora Duggal, Paul Harrison, Antonio Belli, Janet M Lord
BACKGROUND: Almost all studies that have investigated the immune response to trauma have analysed blood samples acquired post-hospital admission. Thus, we know little of the immune status of patients in the immediate postinjury phase and how this might influence patient outcomes. The objective of this study was therefore to comprehensively assess the ultra-early, within 1-hour, immune response to trauma and perform an exploratory analysis of its relationship with the development of multiple organ dysfunction syndrome (MODS)...
July 2017: PLoS Medicine
https://www.readbyqxmd.com/read/28719273/bungarus-multicinctus-multicinctus-snakebite-in-taiwan
#4
Yan-Chiao Mao, Po-Yu Liu, Liao-Chun Chiang, Shu-Chen Liao, Hung-Yuan Su, Szu-Yin Hsieh, Chen-Chang Yang
AbstractAlthough specific antivenom is available in Taiwan, respiratory failure and general pain frequently accompany Bungarus multicinctus envenomation and there have been few reports on the management of B. multicinctus envenomation. We retrospectively analyzed 44 cases of B. multicinctus bite admitted to Taichung Veterans General Hospital (VGH) or to Taipei VGH. Demographic data, treatment, and outcome of patients with and without respiratory failure were compared. In this study, 20.5% patients had bites without noticeable signs or symptoms of significant envenoming, 27...
June 2017: American Journal of Tropical Medicine and Hygiene
https://www.readbyqxmd.com/read/28719084/defending-a-never-event
#5
John R Shepperd
There are medical mishaps that have been deemed "Never Events" by the Centers for Medicare & Medicaid Services (CMS). This term refers generally to preventable occurrences so egregious that they should never occur. But they do occur. And when they do, litigation often follows. This article focuses on one such Never Event-the operating room fire-with strategies on how to defend it. Information provided in this article was derived from a review of the relevant literature and from the author's personal experience defending lawsuits arising from Never Events, including a jury trial involving a surgeon who was sued for a patient's injuries after a fire erupted in the operating room...
July 2017: Journal of Healthcare Risk Management: the Journal of the American Society for Healthcare Risk Management
https://www.readbyqxmd.com/read/28718957/elevated-levels-of-il-22-and-il-17a-producing-t-helper-cells-in-cholangiocarcinomarelated-to-liver-fluke-infection
#6
Si-Biao Su, Jian-Feng Zhang, Fei-Fei Huang, Yu Cen, Hai-Xing Jiang
Cholangiocarcinoma (CCA) associated with liver fluke infection appears to involve inflammatory and immune processes, but whether these involve the proinflammatory cytokine interleukin-17A (IL-17A) and proliferative cytokine interleukin-22 (IL-22) is unclear.We compared levels of IL-22- or IL-17A-producing T helper cells and cytokine levels in 30 CCA patients with long-term liver fluke infection, 40 patients with liver-fluke infection but not CCA and 16 healthy controls. Analyses were performed using immunohistochemistry, flow cytometry, ELISA and RT-PCR...
July 18, 2017: Microbiology and Immunology
https://www.readbyqxmd.com/read/28718734/pullulan-production-from-synthetic-medium-by-a-new-mutant-of-aureobasidium-pullulans
#7
Guoqiang Chen, Jiming Wang, Yulong Su, Youshuang Zhu, Ge Zhang, Hongwei Zhao, Haobao Liu, Ying Yang, Rui Nian, Haibo Zhang, Yuxi Wei, Mo Xian
Pullulan with different molecular-weight could be applied in various fields. A UV-induced mutagenesis Aureobasidium pullulans UVMU6-1 was obtained from the strain A. pullulans CGMCC3.933 for the production of low-molecular-weight pullulan. Firstly, the obtained polysaccharide from A. pullulans UVMU6-1 was purified and identified to be pullulan with TLC, FT-IR and NMR. Then, culture medium and conditions for this strain were optimized by flask fermentation. Based on the optimized medium and culture conditions (pH 4, addition of 4 g/L Tween 80 for 96 h of cultivation), continuously fermentation was performed...
July 18, 2017: Preparative Biochemistry & Biotechnology
https://www.readbyqxmd.com/read/28718674/design-and-synthesis-of-a-novel-photoaffinity-probe-for-labelling-egf-receptor-tyrosine-kinases
#8
You-Guang Zheng, Xiao-Qing Wu, Jun Su, Ping Jiang, Liang Xu, Jian Gao, Bin Cai, Min Ji
The epidermal growth factor receptor (EGFR) and HER2 are two important tyrosine kinases that play crucial roles in signal transduction pathways that regulate numerous cellular functions including proliferation, differentiation, migration, and angiogenesis. In the past 20 years, many proteomic methods have emerged as powerful methods to evaluate proteins in biological processes and human disease states. Among them, activity-based protein profiling (ABPP) is one useful approach for the functional analysis of proteins...
December 2017: Journal of Enzyme Inhibition and Medicinal Chemistry
https://www.readbyqxmd.com/read/28718616/photo-thermally-driven-refreshable-microactuators-based-on-graphene-oxide-doped-paraffin
#9
Sichao Hou, Miao Wang, Shouwu Guo, Ming Su
Actuators based on phase change materials (paraffin) can simultaneously produce large stroke length and large force due to thermal expansion, but the low thermal conductivity of paraffin requires high power input and long actuation time. The graphene oxide (GO) doped paraffin dynamic actuator addresses the key challenges in the design of thermal phase change actuators: Thermal conductivity and light absorbing is increased and the response time is reduced compared to the standard phase change actuator designed with metal heating resistors...
July 18, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28718494/the-hiv-care-cascade-in-buenos-aires-argentina-results-in-a-tertiary-referral-hospital
#10
Carina Cesar, Gabriela Blugerman, José Antonio Valiente, Peter Rebeiro, Omar Sued, Valeria Fink, Mariana Romero Soto, Roberto Cillis, Cleyton Yamamoto, Carlos Falistocco, Pedro Cahn, Héctor Pérez
Objective: To determine rates of retention, antiretroviral therapy (ART) use, and viral suppression in an adult cohort from a public tertiary referral hospital in the city of Buenos Aires, Argentina. Methods: HIV-positive ART-naïve patients ≥ 18 years old starting care 2011-2013 contributed data until the end of 2014. Three outcomes were assessed in 2014: retention in care, ART use, and viral suppression. Patient characteristics associated with each outcome were assessed through logistic regression...
December 2016: Revista Panamericana de Salud Pública, Pan American Journal of Public Health
https://www.readbyqxmd.com/read/28718487/hiv-aids-prevention-care-and-treatment-in-the-region-of-the-americas-achievements-challenges-and-perspectives
#11
Freddy Pérez, Giovanni Ravasi, J Peter Figueroa, Beatriz Grinsztejn, Mary Kamb, Omar Sued, Massimo Ghidinelli
No abstract text is available yet for this article.
December 2016: Revista Panamericana de Salud Pública, Pan American Journal of Public Health
https://www.readbyqxmd.com/read/28718284/achieving-site-selectivity-in-metal-catalyzed-electron-rich-carbene-transfer-reactions-from-n-tosylhydrazones
#12
Naijing Su, Tianning Deng, Donald J Wink, Tom G Driver
Catalyst control of the site-selectivity of electron-rich alkyl, aryl disubstituted carbenes generated in situ from o-alkenyl-substituted N-tosylhydrazones was achieved in this study. Exposure of these substrates to copper iodide triggered the formation of α-alkoxy 2H-naphthalenones. This investigation established that changing the catalyst to a rhodium(II) carboxylate turned off cyclization and migration of the electron-rich metal carbene with the β-carboxylate and turned on allylic C-H bond functionalization to diastereoselectively afford 1H-indenes...
July 18, 2017: Organic Letters
https://www.readbyqxmd.com/read/28717865/heavy-metal-concentrations-in-water-and-soil-along-the-hun-river-liaoning-china
#13
Kan Zhang, Fangli Su, Xianmin Liu, Zhi Song, Xue Feng
Water and soil samples were collected along the Hun River to study the concentrations of Cr, Cu and Zn during the dry season, medium season and wet season in 2013. The concentrations of Cr, Cu, and Zn in Hun River were 0.0010 to 0.1298, 0.0057 to 0.1533 and 0.0162 to 0.5004 mg/L, respectively. The concentrations of Cr, Cu, and Zn in soil from around the Dahuofang reservoir were 0.0033 to 0.2149, 0.0054 to 0.2218 and 0.0135 to 0.3544 mg/g, respectively. The results indicated that the concentrations of Cr, Cu and Zn in water from the Hun River and soil from around the Dahuofang reservoir were significantly different at different sample stations and seasons...
July 17, 2017: Bulletin of Environmental Contamination and Toxicology
https://www.readbyqxmd.com/read/28717834/characterizing-the-adherence-profiles-of-virulent-vibrio-parahaemolyticus-isolates
#14
Alisha M Aagesen, Sureerat Phuvasate, Yi-Cheng Su, Claudia C Häse
The human pathogen Vibrio parahaemolyticus is a leading cause of seafood-borne illness in the USA, and infections with V. parahaemolyticus typically result from eating raw or undercooked oysters. V. parahaemolyticus has been shown to be highly resistant to oyster depuration, suggesting that the bacterium possesses specific mechanisms or factors for colonizing oysters and persisting during depuration. In this study, we characterized eight different V. parahaemolyticus strains for differences in resistance to oyster depuration, biofilm formation, and motility...
July 17, 2017: Microbial Ecology
https://www.readbyqxmd.com/read/28717752/challenges-of-treating-childhood-medulloblastoma-in-a-country-with-limited-resources-20-years-of-experience-at-a-single-tertiary-center-in-malaysia
#15
Revathi Rajagopal, Sayyidatul Abd-Ghafar, Dharmendra Ganesan, Anita Zarina Bustam Mainudin, Kum Thong Wong, Norlisah Ramli, Vida Jawin, Su Han Lum, Tsiao Yi Yap, Eric Bouffet, Ibrahim Qaddoumi, Shekhar Krishnan, Hany Ariffin, Wan Ariffin Abdullah
PURPOSE: Pediatric medulloblastoma (MB) treatment has evolved over the past few decades; however, treating children in countries with limited resources remains challenging. Until now, the literature regarding childhood MB in Malaysia has been nonexistent. Our objectives were to review the demographics and outcome of pediatric MB treated at the University Malaya Medical Center between January 1994 and December 2013 and describe the challenges encountered. METHODS: Fifty-one patients with childhood MB were seen at University Malaya Medical Center...
April 2017: Journal of Global Oncology
https://www.readbyqxmd.com/read/28717649/circular-rna-profiling-and-bioinformatic-modeling-identify-its-regulatory-role-in-hepatic-steatosis
#16
Xing-Ya Guo, Chong-Xin He, Yu-Qin Wang, Chao Sun, Guang-Ming Li, Qing Su, Qin Pan, Jian-Gao Fan
Circular RNAs (circRNAs) exhibit a wide range of physiological and pathological activities. To uncover their role in hepatic steatosis, we investigated the expression profile of circRNAs in HepG2-based hepatic steatosis induced by high-fat stimulation. Differentially expressed circRNAs were subjected to validation using QPCR and functional analyses using principal component analysis, hierarchical clustering, target prediction, gene ontology (GO), and pathway annotation, respectively. Bioinformatic integration established the circRNA-miRNA-mRNA regulatory network so as to identify the mechanisms underlying circRNAs' metabolic effect...
2017: BioMed Research International
https://www.readbyqxmd.com/read/28717648/response-detection-of-castrate-resistant-prostate-cancer-to-clinically-utilised-and-novel-treatments-by-monitoring-phospholipid-metabolism
#17
Tim A D Smith, Su M Phyu, Kholoud S Alzyoud, Chih-Chung Tseng
Androgen receptor (AR) activation is the primary driving factor in prostate cancer which is initially responsive to castration but then becomes resistant (castration-resistant prostate cancer (CRPC)). CRPC cells still retain the functioning AR which can be targeted by other therapies. A recent promising development is the use of inhibitors (Epi-1) of protein-protein interaction to inhibit AR-activated signalling. Translating novel therapies into the clinic requires sensitive early response indicators. Here potential response markers are explored...
2017: BioMed Research International
https://www.readbyqxmd.com/read/28717580/photoacoustic-ultrasound-dual-imaging-of-human-thyroid-cancers-an-initial-clinical-study
#18
Meng Yang, Lingyi Zhao, Xujin He, Na Su, ChenYang Zhao, Hewen Tang, Tao Hong, Wenbo Li, Fang Yang, Lin Lin, Bing Zhang, Rui Zhang, Yuxin Jiang, Changhui Li
We reported an initial clinical study of in vivo human thyroid by a photoacoustic/ultrasound handheld probe. Our dual-modality system is based on a high-end clinical ultrasound machine. Both healthy and cancerous thyroids were imaged non-invasively, and we compared the photoacoustic imaging with color Doppler ultrasound. The results of photoacoustic thyroid imaging could reveal many blood vessels that were not sensitive for Doppler ultrasound. Our study demonstrated that photoacoustic imaging could provide important complementary information for traditional ultrasound thyroid examination, which has a great potential for clinical diagnosis...
July 1, 2017: Biomedical Optics Express
https://www.readbyqxmd.com/read/28717348/the-synergistic-effect-of-microwave-radiation-and-hypergravity-on-rats-and-the-intervention-effect-of-rana-sylvatica-le-conte-oil
#19
Wei Sun, Yudan Yang, Hongmei Yu, Luowei Wang, Su Pan
AIM: The phenomena of hypergravity and microwave radiation are widespread, which cause more and more concern for the hazards to human health. The aim of this study was to investigate the synergistic effect of microwave radiation and hypergravity on rats and observe the protective effect of Rana sylvatica Le conte oil. METHODS: Rats were exposed to microwave radiation and hypergravity, and the rat weight, the climbing pole height, serum enzyme activities, blood urea nitrogen concentration, and total antioxidant capacity were detected...
April 2017: Dose-response: a Publication of International Hormesis Society
https://www.readbyqxmd.com/read/28717228/transformation-of-patchouli-alcohol-to-%C3%AE-patchoulene-by-gastric-juice-%C3%AE-patchoulene-is-more-effective-in-preventing-ethanol-induced-gastric-injury
#20
Yuhong Liu, Jiali Liang, Jiazhen Wu, Hanbin Chen, Zhenbiao Zhang, Hongmei Yang, Liping Chen, Haiming Chen, Ziren Su, Yucui Li
Pogostemonis Herba is a functional food approved in Asian countries. Its major constituent, patchouli alcohol (PA), possesses a gastroprotective effect and is reported to transform into β-patchoulene (β-PAE) under acidic conditions. To investigate whether β-PAE, the metabolite of PA, has a protective effect on the gastrointestinal tract, the formation of β-PAE by gastric juice and the anti-ulcerogenic potential of β-PAE against ethanol-induced gastric injury were evaluated. The Results indicated that PA was converted to β-PAE by rat gastric juice...
July 17, 2017: Scientific Reports
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