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https://www.readbyqxmd.com/read/29161484/-anopheles-darlingi-diptera-culicidae-rood-1926-morphometric-variations-in-wings-and-legs-of-populations-from-colombia
#1
Miguel Alfonso Pacheco, Ranulfo González, Helena Luisa Brochero
INTRODUCTION: Natural populations of Anopheles darlingi, the main malaria vector in Colombia, have shown phenotypic variations in some of their diagnostic characters. OBJECTIVE: To characterize morphometric variations in wing spot patterns and diagnostic characters of the hind leg of adult females of An. darlingi collected in areas where malaria is endemic. MATERIALS AND METHODS: Patterns of the costal vein spots of wild females of An. darling populations collected in the departments of Chocó, Guaviare, Meta and Vichada were analyzed using linear and morphometric approaches...
March 29, 2017: Biomédica: Revista del Instituto Nacional de Salud
https://www.readbyqxmd.com/read/29160110/peroxiredoxin6-a-multitask-antioxidant-enzyme-involved-in-the-pathophysiology-of-chronic-non-communicable-diseases
#2
Francesca Pacifici, David Della-Morte, Barbara Capuani, Donatella Pastore, Alfonso Bellia, Paolo Sbraccia, Nicola Di Daniele, Renato Lauro, Davide Lauro
SIGNIFICANCE: Chronic Non-Communicable Diseases (NCDs) are the leading causes of disability and death worldwide. NCDs mainly comprise diabetes mellitus, cardiovascular diseases, chronic obstructive pulmonary disease (COPD), cancer, and neurological degenerative diseases, which kill more than 80% of population, especially elderlies, worldwide. Recent Advances: Several recent theories established NCDs as multifactorial diseases, where a combination of genetic, epigenetic and environmental factors contributes to their pathogenesis...
November 21, 2017: Antioxidants & Redox Signaling
https://www.readbyqxmd.com/read/29159183/patients-affected-by-unmethylated-o-6-methylguanine-dna-methyltransferase-glioblastoma-undergoing-radiochemotherapy-may-benefit-from-moderately-dose-escalated-radiotherapy
#3
Paolo Tini, Valerio Nardone, Pierpaolo Pastina, Giuseppe Battaglia, Clelia Miracco, Lucio Sebaste, Giovanni Rubino, Alfonso Cerase, Luigi Pirtoli
Purpose: To compare the therapeutic results of two radiotherapy (RT) dose schedules in combined temozolomide- (TMZ-) RT treatment in newly diagnosed glioblastoma (GB), according to the O(6)-methylguanine-DNA methyltransferase (MGMT) methylation status. Material and Method: Patients received either standard (60 Gy) or moderately escalated dose (70 Gy) radiotherapy (RT) with concomitant and adjuvant TMZ between June 2006 and October 2013. We retrospectively evaluated the therapeutic effectiveness of RT schedules in terms of Overall Survival (OS) and Progression-Disease Free Survival (PDFS) analyzing the MGMT methylation status...
2017: BioMed Research International
https://www.readbyqxmd.com/read/29158887/medical-imaging-lesion-detection-based-on-unified-gravitational-fuzzy-clustering
#4
Jean Marie Vianney Kinani, Alberto Jorge Rosales Silva, Francisco Gallegos Funes, Dante Mújica Vargas, Eduardo Ramos Díaz, Alfonso Arellano
We develop a swift, robust, and practical tool for detecting brain lesions with minimal user intervention to assist clinicians and researchers in the diagnosis process, radiosurgery planning, and assessment of the patient's response to the therapy. We propose a unified gravitational fuzzy clustering-based segmentation algorithm, which integrates the Newtonian concept of gravity into fuzzy clustering. We first perform fuzzy rule-based image enhancement on our database which is comprised of T1/T2 weighted magnetic resonance (MR) and fluid-attenuated inversion recovery (FLAIR) images to facilitate a smoother segmentation...
2017: Journal of Healthcare Engineering
https://www.readbyqxmd.com/read/29155900/correction-a-massive-update-of-non-indigenous-species-records-in-mediterranean-marinas
#5
Aylin Ulman, Jasmine Ferrario, Anna Occhpinti-Ambrogi, Christos Arvanitidis, Ada Bandi, Marco Bertolino, Cesare Bogi, Giorgos Chatzigeorgiou, Burak Ali Çiçek, Alan Deidun, Alfonso Ramos-Esplá, Cengiz Koçak, Maurizio Lorenti, Gemma Martinez-Laiz, Guenda Merlo, Elisa Princisgh, Giovanni Scribano, Agnese Marchini
[This corrects the article DOI: 10.7717/peerj.3954.].
2017: PeerJ
https://www.readbyqxmd.com/read/29155809/multivariate-pattern-dependence
#6
Stefano Anzellotti, Alfonso Caramazza, Rebecca Saxe
When we perform a cognitive task, multiple brain regions are engaged. Understanding how these regions interact is a fundamental step to uncover the neural bases of behavior. Most research on the interactions between brain regions has focused on the univariate responses in the regions. However, fine grained patterns of response encode important information, as shown by multivariate pattern analysis. In the present article, we introduce and apply multivariate pattern dependence (MVPD): a technique to study the statistical dependence between brain regions in humans in terms of the multivariate relations between their patterns of responses...
November 20, 2017: PLoS Computational Biology
https://www.readbyqxmd.com/read/29155382/very-late-scaffold-thrombosis-insights-from-optical-coherence-tomography-and-histopathology
#7
Michael Joner, Philipp Nicol, Himanshu Rai, Heiko Richter, Nicolas Foin, Jaryl Ng, Javier Cuesta, Fernando Rivero, Rosario Serrano, Fernando Alfonso
No abstract text is available yet for this article.
November 21, 2017: EuroIntervention
https://www.readbyqxmd.com/read/29154255/trial-latencies-estimation-of-event-related-potentials-in-eeg-by-means-of-genetic-algorithms
#8
Paolo Da Pelo, Marina De Tommaso, Alfonso Monaco, Sebastiano Stramaglia, Roberto Bellotti, Sabina Tangaro
Objective Event-Related Potentials are usually obtained by averaging thus neglecting the trial-to-trial latency variability in cognitive EEG responses. As a consequence the shape and the peak amplitude of the averaged ERP are smeared and reduced, respectively, when the single trial latencies show a relevant variability. To date, the majority of the methodologies for single-trial latencies inference are iterative schemes providing sub-optimal solutions, the most commonly used being the Woody's algorithm...
November 20, 2017: Journal of Neural Engineering
https://www.readbyqxmd.com/read/29153462/health-related-quality-of-life-and-toxicity-after-single-fraction-19%C3%A2-gy-high-dose-rate-prostate-brachytherapy-phase-ii-trial
#9
Alfonso Gomez-Iturriaga, Francisco Casquero, Jose Ignacio Pijoan, Pablo Minguez, Jose Maria Espinosa, Ana Irasarri, Andrea Bueso, Jon Cacicedo, David Buchser, Pedro Bilbao
PURPOSE: To evaluate the safety, tolerance and impact on health-related-quality-of-life (HRQoL) of the high-dose-rate brachytherapy of 19 Gy (BRT-HDR-19 Gy) single fraction in prostate cancer. METHODS: From January 2014 to July 2016, 43 patients with low/intermediate risk were treated with BRT-HDR-19 Gy. The patients were monitored prospectively for toxicity and HRQoL. RESULTS: The median age, initial PSA and the International Prostate Symptom Score (IPSS) were 71 years (55-78), 7...
November 15, 2017: Radiotherapy and Oncology: Journal of the European Society for Therapeutic Radiology and Oncology
https://www.readbyqxmd.com/read/29152990/gastroduodenal-lesions-detected-during-small-bowel-capsule-endoscopy-incidence-diagnostic-and-therapeutic-impact
#10
José Francisco Juanmartiñena Fernández, Ignacio Fernández-Urien Sainz, Beatriz Zabalza Ollo, Cristina Saldaña Dueñas, Marta Montañés Guimera, Alfonso Elosua González, Juan José Vila Costas
BACKGROUND: Capsule endoscopy was primarily designed for the investigation of the small bowel. However, it may also identify lesions in other segments of the gastrointestinal tract. The aim of the current study was to evaluate the incidence of gastroduodenal abnormalities during small bowel capsule endoscopy and its impact on patient diagnosis and management. PATIENTS AND METHODS: This study is a retrospective analysis of data from 2,217 consecutive capsule endoscopy procedures performed at a single tertiary-care center between January 2008 and February 2016...
November 20, 2017: Revista Española de Enfermedades Digestivas
https://www.readbyqxmd.com/read/29152692/left-frontoparietal-network-activity-is-modulated-by-drug-stimuli-in-cocaine-addiction
#11
Víctor Costumero, Patricia Rosell-Negre, Juan Carlos Bustamante, Paola Fuentes-Claramonte, Juan José Llopis, Cesar Ávila, Alfonso Barrós-Loscertales
Cocaine addicts present reduced activity in the left frontoparietal network, a brain network associated with cognitive control, during the processing of non-drug reward related stimuli (Costumero et al., Addiction Biology 22:479-489, 2015). However, the involvement of this network in drug-related stimuli processing remains unclear. Here, fifteen cocaine-dependent men and fifteen healthy matched controls viewed cocaine-related, erotic, aversive, and neutral pictures during an fMRI session. Group independent component analysis was then performed to investigate how functional networks were modulated by the different emotional images...
November 20, 2017: Brain Imaging and Behavior
https://www.readbyqxmd.com/read/29152540/if-you-build-it-who-will-come-a-description-of-user-characteristics-and-experiences-with-the-mcmaster-optimal-aging-portal
#12
Sarah E Neil-Sztramko, Rawan Farran, Susannah Watson, Anthony J Levinson, John N Lavis, Alfonso Iorio, Maureen Dobbins
Objectives: The McMaster Optimal Aging Portal (the Portal) aims to increase access to evidence-based health information. We would now like to understand who uses the Portal, why, and for what, and elicit feedback and suggestions for future initiatives. Methods: An online survey of users collected data on demographics, eHealth literacy, Internet use, information-seeking behavior, site acceptability and perceived impact on health behaviors, participant satisfaction, and suggestions for improvements using mixed methods...
January 2017: Gerontology & Geriatric Medicine
https://www.readbyqxmd.com/read/29151897/community-acquired-infection-with-hypervirulent-clostridium-difficile-isolates-that-carry-different-toxin-and-antibiotic-resistance-loci-a-case-report
#13
Marina Muñoz, Milena Camargo, Dora Inés Ríos-Chaparro, Paula Gómez, Manuel Alfonso Patarroyo, Juan David Ramírez
Background: Clostridium difficile infection (CDI) leads to the onset of antibiotic-associated diarrhea (AAD) and a wide range of gastrointestinal pathologies. Currently, CDI is one of the most important opportunistic infections at the intrahospital level and an exponential increase in community-acquired infections has been reported. Herein, we evaluated the relationships (at phylogenetic and genetic population structure levels), as well as the molecular toxigenic and antibiotic resistance profiles of a set of isolates established from a case of community acquired-CDI...
2017: Gut Pathogens
https://www.readbyqxmd.com/read/29149644/assessing-the-risk-of-laparoscopic-morcellation-of-occult-uterine-sarcomas-during-hysterectomy-and-myomectomy-literature-review-and-the-isge-recommendations
#14
REVIEW
Ornella Sizzi, Lucia Manganaro, Alfonso Rossetti, Matteo Saldari, Giuseppe Florio, Alessandro Loddo, Robert Zurawin, Bruno van Herendael, Dusan Djokovic
OBJECTIVE: This project of the International Society for Gynecologic Endoscopy (ISGE) had the objective to review the literature and provide recommendations on the occult sarcoma risk assessment in patients who are candidates for minimally invasive gynecological surgery involving intra-abdominal electromechanical tissue morcellation. STUDY DESIGN: The ISGE Task Force for Estimation of the Risk in Endoscopic Morcellation initially defined key topics and clinical questions which may guide a comprehensive preoperative patient assessment...
November 7, 2017: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://www.readbyqxmd.com/read/29149212/mycolactone-displays-anti-inflammatory-effects-on-the-nervous-system
#15
Caroline Isaac, Annie Mauborgne, Alfonso Grimaldi, Kemy Ade, Michel Pohl, Cristina Limatola, Yves Boucher, Caroline Demangel, Laure Guenin-Macé
BACKGROUND: Mycolactone is a macrolide produced by the skin pathogen Mycobacterium ulcerans, with cytotoxic, analgesic and immunomodulatory properties. The latter were recently shown to result from mycolactone blocking the Sec61-dependent production of pro-inflammatory mediators by immune cells. Here we investigated whether mycolactone similarly affects the inflammatory responses of the nervous cell subsets involved in pain perception, transmission and maintenance. We also investigated the effects of mycolactone on the neuroinflammation that is associated with chronic pain in vivo...
November 2017: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/29148901/glaucoma-in-patients-with-shunt-treated-normal-pressure-hydrocephalus
#16
Pasquale Gallina, Alfonso Savastano, Eleonora Becattini, Simone Orlandini, Antonio Scollato, Stanislao Rizzo, Giulia Carreras, Nicola Di Lorenzo, Berardino Porfirio
OBJECTIVE Changes in the pressure gradient between intraocular and intracranial compartments at the lamina cribrosa level are a possible explanation of normal tension glaucoma (NTG). Shunt-treated normal pressure hydrocephalus (NPH) is a model for testing whether the increase (time from disease onset to CSF shunt placement, i.e., "protection period") and decrease (time from shunt placement to observation, i.e., "exposure period") in intracranial pressure (ICP) are glaucoma protective or risk factors, respectively...
November 17, 2017: Journal of Neurosurgery
https://www.readbyqxmd.com/read/29147884/ocular-flutter-following-zika-virus-infection
#17
Emely Karam, Jose Giraldo, Flor Rodriguez, Carlos E Hernandez-Pereira, Alfonso J Rodriguez-Morales, Gabriela M Blohm, Alberto E Paniz-Mondolfi
Zika virus (ZIKV) is an emerging flavivirus which has been linked to a number of neurologic manifestations such as Guillain-Barré syndrome (GBS), transverse myelitis, and meningo-encephalitis. Ophthalmologic manifestations are increasingly being reported; however, ocular dyskinesias have not been described in this context to date. Herein, we report a case of a 22-year-old female who presented with ocular flutter and associated Guillain-Barré syndrome following acute ZIKV infection. We speculate that although such symptoms may have originated from a direct viral insult, a post-infectious autoimmune mechanism may not be excluded...
November 16, 2017: Journal of Neurovirology
https://www.readbyqxmd.com/read/29147660/analytical-validation-of-a-new-enzymatic-and-automatable-method-for-d-xylose-measurement-in-human-urine-samples
#18
Israel Sánchez-Moreno, Carmen Monsalve-Hernando, Ana Godino, Luis Illa, María Jesús Gaspar, Guillermo Manuel Muñoz, Ana Díaz, José Luis Martín, Eduardo García-Junceda, Alfonso Fernández-Mayoralas, Carmen Hermida
Hypolactasia, or intestinal lactase deficiency, affects more than half of the world population. Currently, xylose quantification in urine after gaxilose oral administration for the noninvasive diagnosis of hypolactasia is performed with the hand-operated nonautomatable phloroglucinol reaction. This work demonstrates that a new enzymatic xylose quantification method, based on the activity of xylose dehydrogenase from Caulobacter crescentus, represents an excellent alternative to the manual phloroglucinol reaction...
2017: BioMed Research International
https://www.readbyqxmd.com/read/29146275/beat-to-beat-variations-in-activation-recovery-interval-derived-from-the-right-ventricular-electrogram-can-monitor-arrhythmic-risk-under-anesthetic-and-awake-conditions-in-the-canine-chronic-atrioventricular-block-model
#19
Sofieke C Wijers, David J Sprenkeler, Alexandre Bossu, Albert Dunnink, Jet D M Beekman, Rosanne Varkevisser, Alfonso Aranda Hernández, Mathias Meine, Marc A Vos
BACKGROUND: In the chronic atrioventricular block (CAVB) dog model, beat-to-beat variation of repolarization in the left ventricle (LV) quantified as short-term variability of the left monophasic action potential duration (STVLVMAPD) increases abruptly upon challenge with a pro arrhythmic drug. This increase occurs before the first ectopic beat (EB), specifically in subjects that demonstrate subsequent repetitive Torsade de Pointes arrhythmias (TdP). OBJECTIVE: Demonstrate that STV is feasible to monitor arrhythmic risk through the use of the intracardiac electrogram (EGM) derived from the right ventricle (RV) lead from pacemakers or implantable cardioverter defibrillators (ICD)...
November 13, 2017: Heart Rhythm: the Official Journal of the Heart Rhythm Society
https://www.readbyqxmd.com/read/29145940/happy-classes-make-happy-students-classmates-well-being-predicts-individual-student-well-being
#20
Ronnel B King, Jesus Alfonso Datu
Student well-being has mostly been studied as an individual phenomenon with little research investigating how the well-being of one's classmates could influence a student's well-being. The aim of the current study was to examine how the aggregate well-being of students who comprise a class could predict students' subsequent well-being (Time 2 well-being) after controlling for the effects of prior well-being (Time 1 well-being) as well as key demographic variables such as gender and age. Two studies among Filipino secondary school students were conducted...
December 2017: Journal of School Psychology
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