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Process communications model

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https://www.readbyqxmd.com/read/29139220/creating-and-facilitating-change-for-person-centred-coordinated-care-p3c-the-development-of-the-organisational-change-tool-p3c-oct
#1
Jane Horrell, Helen Lloyd, Thavapriya Sugavanam, James Close, Richard Byng
BACKGROUND: Person Centred Coordinated Care (P3C) is a UK priority for patients, carers, professionals, commissioners and policy makers. Services are developing a range of approaches to deliver this care with a lack of tools to guide implementation. METHODOLOGY: A scoping review and critical examination of current policy, key literature and NHS guidelines, together with stakeholder involvement led to the identification of domains, subdomains and component activities (processes and behaviours) required to deliver P3C...
November 15, 2017: Health Expectations: An International Journal of Public Participation in Health Care and Health Policy
https://www.readbyqxmd.com/read/29138108/analysis-of-social-process-in-two-inbred-strains-of-male-mice-a-predominance-of-contact-based-investigation-in-balb-c-mice
#2
Hiroyuki Arakawa
Developing mouse models for social communication deficits requires a better understanding of the nature of social investigatory processes between mice. Mice use different investigatory strategies based on a possibility of contacts with social sources. A detailed investigation of contact distance revealed strain differences in behavioral strategy between two male inbred C57BL/6 (B6) and BALB/c (BALB) mouse strains. When direct physical contact with stimulus mice was restricted, BALB mice displayed lower social approaches than B6 mice, accompanied by heightened innate anxiety in an unfamiliar environment...
November 11, 2017: Neuroscience
https://www.readbyqxmd.com/read/29137392/selective-secretion-of-micrornas-from-lung-cancer-cells-via-extracellular-vesicles-promotes-camk1d-mediated-tube-formation-in-endothelial-cells
#3
James Lawson, Christopher Dickman, Sara MacLellan, Rebecca Towle, James Jabalee, Stephen Lam, Cathie Garnis
Extracellular vesicles (EVs) are key signaling mediators between cancer cells and their supporting stroma, and regulate critical processes such as invasion, metastases, and angiogenesis. We have identified a subset of miRNAs (miR-142-3p, miR-143-3p, miR-145-5p, miR-150-5p, miR-223-3p, miR-451a, miR-486-5p, miR-605-5p) that are enriched in lung adenocarcinoma extracellular vesicles compared to the donor cells from which they were derived. Two well-known tumor suppressors, miR-143-3p and miR-145-5p, were also enriched in serum samples collected during surgery from blood vessels draining directly from lung adenocarcinoma tumor beds...
October 13, 2017: Oncotarget
https://www.readbyqxmd.com/read/29135285/factors-associated-with-confidence-in-decision-making-and-satisfaction-with-risk-communication-among-patients-with-atrial-fibrillation
#4
Berith Hedberg, Dan Malm, Jan-Erik Karlsson, Kristofer Årestedt, Anders Broström
BACKGROUND: Atrial fibrillation is a prevalent cardiac arrhythmia. Effective communication of risks (e.g. stroke risk) and benefits of treatment (e.g. oral anticoagulants) is crucial for the process of shared decision making. AIM: The aim of this study was to explore factors associated with confidence in decision making and satisfaction with risk communication after a follow-up visit among patients who three months earlier had visited an emergency room for atrial fibrillation related symptoms...
November 1, 2017: European Journal of Cardiovascular Nursing
https://www.readbyqxmd.com/read/29133435/coordinated-plasticity-of-synapses-and-astrocytes-underlies-practice-driven-functional-vicariation-in-peri-infarct-motor-cortex
#5
Soo Young Kim, J Edward Hsu, Lincoln C Husbands, Jeffrey A Kleim, Theresa A Jones
Motor rehabilitative training after stroke can improve motor function and promote topographical reorganization of remaining motor cortical movement representations, but this reorganization follows behavioral improvements. A more detailed understanding of the neural bases of rehabilitation efficacy is needed to inform therapeutic efforts to improve it. Using a rat model of upper extremity impairments after ischemic stroke, we examined effects of motor rehabilitative training at the ultrastructural level in peri-infarct motor cortex...
November 13, 2017: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
https://www.readbyqxmd.com/read/29133246/potentially-inappropriate-liver-transplantation-in-the-era-of-the-sickest-first-policy-a-search-for-the-upper-limits
#6
REVIEW
Michael Linecker, Tanja Krones, Thomas Berg, Claus U Niemann, Randolph H Steadman, Philipp Dutkowski, Pierre-Alain Clavien, Ronald W Busuttil, Robert D Truog, Henrik Petrowsky
Liver transplantation has emerged to a highly efficient treatment for a variaty of acute and chronic liver diseases. Organ shortage, however, is becoming an increasing problem worldwide, limiting the applicability of liver transplantation. In addition, potential recipients are becoming sicker, thereby increasing the risk of loosing the graft during transplantation or in the initial post-operative period after liver transplantation (3 months). This trend is challenging the MELD allocation model where sickest candidates are prioritized and no delisting criteria are given...
November 10, 2017: Journal of Hepatology
https://www.readbyqxmd.com/read/29131516/performance-in-a-collaborative-search-task-the-role-of-feedback-and-alignment
#7
Moreno I Coco, Rick Dale, Frank Keller
When people communicate, they coordinate a wide range of linguistic and non-linguistic behaviors. This process of coordination is called alignment, and it is assumed to be fundamental to successful communication. In this paper, we question this assumption and investigate whether disalignment is a more successful strategy in some cases. More specifically, we hypothesize that alignment correlates with task success only when communication is interactive. We present results from a spot-the-difference task in which dyads of interlocutors have to decide whether they are viewing the same scene or not...
November 13, 2017: Topics in Cognitive Science
https://www.readbyqxmd.com/read/29128405/systems-cues-governing-il6-signaling-in-leishmaniasis
#8
Bhavnita Soni, Bhaskar Saha, Shailza Singh
IL-6 has been proposed to favor the development of Th2 responses and play an important role in the communication between cells of multicellular organisms. They are involved in the regulation of complex cellular processes such as proliferation, differentiation and act as key player during inflammation and immune response. Th2 cytokines play an immunoregulatory role in early infection. Literature says in mice infected with L. major, IL-6 may promote the development of both Th1 and Th2 responses. IL-4 is also considered to be the signature cytokine of Th-2 response...
November 8, 2017: Cytokine
https://www.readbyqxmd.com/read/29122586/the-evolutionary-dynamics-of-language
#9
REVIEW
Luc Steels, Eörs Szathmáry
The well-established framework of evolutionary dynamics can be applied to the fascinating open problems how human brains are able to acquire and adapt language and how languages change in a population. Schemas for handling grammatical constructions are the replicating unit. They emerge and multiply with variation in the brains of individuals and undergo selection based on their contribution to needed expressive power, communicative success and the reduction of cognitive effort. Adopting this perspective has two major benefits...
November 6, 2017: Bio Systems
https://www.readbyqxmd.com/read/29121051/process-evaluation-of-knowledge-transfer-across-industries-leveraging-coca-cola-s-supply-chain-expertise-for-medicine-availability-in-tanzania
#10
Erika Linnander, Christina T Yuan, Shirin Ahmed, Emily Cherlin, Kristina Talbert-Slagle, Leslie A Curry
Persistent gaps in the availability of essential medicines have slowed the achievement of global health targets. Despite the supply chain knowledge and expertise that ministries of health might glean from other industries, limited empirical research has examined the process of knowledge transfer from other industries into global public health. We examined a partnership designed to improve the availability of medical supplies in Tanzania by transferring knowledge from The Coca-Cola system to Tanzania's Medical Stores Department (MSD)...
2017: PloS One
https://www.readbyqxmd.com/read/29118414/cellular%C3%A2-information-dynamics-through-transmembrane-flow-of-ions
#11
Robert A Gatenby, B Roy Frieden
We propose cells generate large transmembrane ion gradients to form information circuits that detect, process, and respond to environmental perturbations or signals. In this model, the specialized gates of transmembrane ion channels function as information detectors that communicate to the cell through rapid and (usually) local pulses of ions. Information in the ion "puffs" is received and processed by the cell through resulting changes in charge density and/or mobile cation (and/or anion) concentrations alter the localization and function of peripheral membrane proteins...
November 8, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29115301/mechanical-forces-direct-stem-cell-behaviour-in-development-and-regeneration
#12
REVIEW
Kyle H Vining, David J Mooney
Stem cells and their local microenvironment, or niche, communicate through mechanical cues to regulate cell fate and cell behaviour and to guide developmental processes. During embryonic development, mechanical forces are involved in patterning and organogenesis. The physical environment of pluripotent stem cells regulates their self-renewal and differentiation. Mechanical and physical cues are also important in adult tissues, where adult stem cells require physical interactions with the extracellular matrix to maintain their potency...
November 8, 2017: Nature Reviews. Molecular Cell Biology
https://www.readbyqxmd.com/read/29113081/coverage-probability-and-area-spectral-efficiency-of-clustered-linear-unmanned-vehicle-sensor-networks
#13
Haejoon Jung, In-Ho Lee
In this paper, we consider clustered unmanned vehicle (UV) sensor networks for swarm sensing applications in a linear structure such as highway, tunnel, underwater pipelines, power lines, and international border. We assume that the linear UV sensor networks follow Thomas cluster process (TCP), in which the cluster locations are modelled by Poisson point process (PPP), while the cluster members (UVs) are normally distributed around their cluster centers. We focus on communications between UVs within a cluster such as local sensing data transfer or swarm coordination, where multiple UV pairs can share the same frequency band simultaneously...
November 5, 2017: Sensors
https://www.readbyqxmd.com/read/29112408/ensemble-and-rigidity-theory-based-perturbation-approach-to-analyze-dynamic-allostery
#14
Christopher Pfleger, Alexander Minges, Markus Boehm, Christopher L McClendon, Rubben Torella, Holger Gohlke
Allostery describes the functional coupling between sites in biomolecules. Recently, the role of changes in protein dynamics for allosteric communication has been highlighted. A quantitative and predictive description of allostery is fundamental for understanding biological processes. Here, we integrate an ensemble-based perturbation approach with the analysis of biomolecular rigidity and flexibility to construct a model of dynamic allostery. Our model by definition excludes the possibility of conformational changes, evaluates static, not dynamic, properties of molecular systems, and describes allosteric effects due to ligand binding in terms of a novel free energy measure...
November 7, 2017: Journal of Chemical Theory and Computation
https://www.readbyqxmd.com/read/29109240/deficiency-of-the-thyroid-hormone-transporter-mct8-in-neural-progenitors-impairs-cellular-processes-crucial-for-early-corticogenesis
#15
Pieter Vancamp, Marie-Anne Deprez, Michiel Remmerie, Veerle M Darras
Thyroid hormones (THs) are essential for establishing layered brain structures, a process called corticogenesis, by acting on transcriptional activity of numerous genes. In humans, deficiency of the monocarboxylate transporter 8 (MCT8), involved in cellular uptake of THs prior to their action, results in severe neurological abnormalities, known as the Allan-Herndon-Dudley Syndrome. While the brain lesions predominantly originate prenatally, it remains unclear how and when exactly MCT8 dysfunction affects cellular processes crucial for corticogenesis...
November 6, 2017: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
https://www.readbyqxmd.com/read/29109079/a-three-talk-model-for-shared-decision-making-multistage-consultation-process
#16
Glyn Elwyn, Marie Anne Durand, Julia Song, Johanna Aarts, Paul J Barr, Zackary Berger, Nan Cochran, Dominick Frosch, Dariusz Galasiński, Pål Gulbrandsen, Paul K J Han, Martin Härter, Paul Kinnersley, Amy Lloyd, Manish Mishra, Lilisbeth Perestelo-Perez, Isabelle Scholl, Kounosuke Tomori, Lyndal Trevena, Holly O Witteman, Trudy Van der Weijden
Objectives To revise an existing three-talk model for learning how to achieve shared decision making, and to consult with relevant stakeholders to update and obtain wider engagement.Design Multistage consultation process.Setting Key informant group, communities of interest, and survey of clinical specialties.Participants 19 key informants, 153 member responses from multiple communities of interest, and 316 responses to an online survey from medically qualified clinicians from six specialties.Results After extended consultation over three iterations, we revised the three-talk model by making changes to one talk category, adding the need to elicit patient goals, providing a clear set of tasks for each talk category, and adding suggested scripts to illustrate each step...
November 6, 2017: BMJ: British Medical Journal
https://www.readbyqxmd.com/read/29107870/consent-process-for-us-based-family-reference-dna-samples
#17
Sara H Katsanis, Lindsey Snyder, Kelly Arnholt, Amy Z Mundorff
DNA collection from family members of the missing is a tenet for missing persons' and mass fatality investigations. Procedures for consenting family members are disparate, depending on the context supporting the reason for sample collection. While guidelines and best practices have been developed for handling mass fatalities and for identification of the missing, these guidelines do not address standard consent practices for living family members of potential victims. We examined the relevant U.S. laws, international guidelines and best practices, sampled consent forms currently used for DNA collection of family members, and drafted model language for a consent form to communicate the required and recommended information...
October 29, 2017: Forensic Science International. Genetics
https://www.readbyqxmd.com/read/29104303/gpu-accelerated-red-blood-cells-simulations-with-transport-dissipative-particle-dynamics
#18
Ansel L Blumers, Yu-Hang Tang, Zhen Li, Xuejin Li, George E Karniadakis
Mesoscopic numerical simulations provide a unique approach for the quantification of the chemical influences on red blood cell functionalities. The transport Dissipative Particles Dynamics (tDPD) method can lead to such effective multiscale simulations due to its ability to simultaneously capture mesoscopic advection, diffusion, and reaction. In this paper, we present a GPU-accelerated red blood cell simulation package based on a tDPD adaptation of our red blood cell model, which can correctly recover the cell membrane viscosity, elasticity, bending stiffness, and cross-membrane chemical transport...
August 2017: Computer Physics Communications
https://www.readbyqxmd.com/read/29103713/short-communication-circulating-fatty-acylcarnitines-are-elevated-in-overweight-periparturient-dairy-cows-in-association-with-sphingolipid-biomarkers-of-insulin-resistance
#19
J E Rico, Y Zang, N J Haughey, A G Rius, J W McFadden
Defects in mitochondrial fatty acid processing are associated with the development of fatty liver disease, inflammation, and insulin resistance in overweight nonruminants. Surplus fatty acids (FA) and defects in FA oxidation favor the accumulation of fatty acylcarnitines (FAC) and the sphingolipid ceramide. Moreover, elevated circulating FAC and ceramide concentrations are inversely related to insulin action. Because we have previously demonstrated that plasma ceramide levels increase during the transition from gestation to lactation, our aim was to determine whether changes in plasma medium- and long-chain FAC levels are related to circulating FA and sphingolipids in peripartal dairy cows...
November 2, 2017: Journal of Dairy Science
https://www.readbyqxmd.com/read/29103150/caregiver-social-support-quality-when-interacting-with-cancer-survivors-advancing-the-dual-process-model-of-supportive-communication
#20
Jacquelyn Harvey-Knowles, Meara H Faw
Cancer caregivers often experience significant challenges in their motivation and ability to comfort cancer survivors, particularly in a spousal or romantic context. Spousal cancer caregivers have been known to report even greater levels of burden and distress than cancer sufferers, yet still take on the role of acting as an informal caregiver so they can attend to their partner's needs. The current study tested whether a theoretical model of supportive outcomes-the dual-process model of supportive communication-explained variations in cancer caregivers' motivation and ability to create high-quality support messages...
November 4, 2017: Supportive Care in Cancer: Official Journal of the Multinational Association of Supportive Care in Cancer
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