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https://www.readbyqxmd.com/read/29036185/impact-of-social-inequalities-at-birth-on-the-longevity-of-children-born-1914-1916-a-cohort-study
#1
Nicolas Todd, Sophie Le Fur, Pierre Bougnères, Alain-Jacques Valleron
BACKGROUND: Testing whether familial socioeconomic status (SES) in childhood is a predictor of mortality has rarely been done on historical cohorts. METHODS: The birth certificates of 4,805 individuals born 1914-1916 in 16 districts of the Paris region were retrieved. The handwritten information provided the occupation of parents, the legitimacy status, life events (e.g. marriage, divorce), and the precise date of death when after 1945 (i.e. age 31 years (y) in the cohort)...
2017: PloS One
https://www.readbyqxmd.com/read/29035457/evaluation-of-mir-203-expression-levels-and-dna-promoter-methylation-status-in-serum-of-patients-with-endometrial-cancer
#2
Marco Benati, Martina Montagnana, Elisa Danese, Elisa Paviati, Silvia Giudici, Massimo Franchi, Giuseppe Lippi
BACKGROUND: Endometrial cancer (EC) is currently considered the fourth most frequent female cancer in Europe. In an attempt to achieve an early diagnosis, many studies have identified some putative biomarkers for gynecologic cancers, including circulating microRNAs (miRs) and aberrant promoter methylation status. Previous studies which have investigated miR-203 expression profiles in EC tissues and normal endometrial tissues concluded that miR-203 is regulated by methylation promoter...
October 1, 2017: Clinical Laboratory
https://www.readbyqxmd.com/read/29033175/projecting-temperature-related-years-of-life-lost-under-different-climate-change-scenarios-in-one-temperate-megacity-china
#3
Yixue Li, Guoxing Li, Qiang Zeng, Fengchao Liang, Xiaochuan Pan
Temperature has been associated with population health, but few studies have projected the future temperature-related years of life lost attributable to climate change. To project future temperature-related disease burden in Tianjin, we selected years of life lost (YLL) as the dependent variable to explore YLL attributable to climate change. A generalized linear model (GLM) and distributed lag non-linear model were combined to assess the non-linear and delayed effects of temperature on the YLL of non-accidental mortality...
October 12, 2017: Environmental Pollution
https://www.readbyqxmd.com/read/29032788/using-the-bergman-paris-question-to-screen-seniors-in-the-emergency-department
#4
Antoine Lague, Philippe Voyer, Marie-Christine Ouellet, Vale Rie Boucher, Marianne Giroux, Mathieu Pelletier, E Milie Gouin, Raoul Daoust, Simon Berthelot, Miche le Morin, Thien Tuong Minh Vu, Jacques Lee, Audrey-Anne Brousseau, Marie-Jose E Sirois, Marcel E Mond
OBJECTIVES: In the fast pace of the Emergency Department (ED), clinicians are in need of tailored screening tools to detect seniors who are at risk of adverse outcomes. We aimed to explore the usefulness of the Bergman-Paris Question (BPQ) to expose potential undetected geriatric syndromes in community-living seniors presenting to the ED. METHODS: This is a planned sub-study of the INDEED multicentre prospective cohort study, including independent or semi-independent seniors (≥65 years old) admitted to hospital after an ED stay ≥8 hours and who were not delirious...
October 16, 2017: CJEM
https://www.readbyqxmd.com/read/29030147/-report-from-the-cfef-seminar-on-fetal-biometry-june-2017
#5
Collège Français d'échographie Fœtale Cfef
This article reports the conclusions and recommendations resulting from the seminar organized in Paris on June 15, 2017 by the scientific committee of the French College of Fetal Ultrasound (CFEF). The purpose of this meeting was to audit the practices in screening for SGA and IUGR fetuses in France and to discuss ways to improve ultrasound screening. A review of charts, references, standards and common practices was performed. The potential new biometric tools applicable in France were reviewed and analyzed...
October 10, 2017: Gynecologie, Obstetrique, Fertilite & Senologie
https://www.readbyqxmd.com/read/29030143/impact-of-atrial-fibrillation-on-outcomes-with-motor-vehicle-accidents
#6
Kanishk Agnihotri, N V Pothineni, Paris Charilaou, Vaibhav R Vaidya, Badal Thakkar, Vishal Goyal, Sabeeda Kadavath, Nileshkumar Patel, Apurva Badheka, Peter Noseworthy, Suraj Kapa, Paul Friedman, Bernard Gersh, Hakan Paydak, Abhishek Deshmukh
BACKGROUND: We examined the effect of AF a commonly encountered arrhythmia with significant morbidity on mortality following a motor vehicle accident (MVA) related hospitalization. METHODS: The Nationwide Inpatient Sample (NIS) was queried to identify patients with AF (ICD-9 CM 427.31) and MVA (ICD-9 CM E810.0-E819.9), considered separately and together, from 2003 through 2012. Baseline characteristics were identified and multilevel mixed model multivariate analysis was employed to verify the impact of AF on in-patient mortality in survivors...
October 3, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/29030034/a-novel-polyacrylamide-based-silica-stationary-phase-for-the-separation-of-carbohydrates-using-alcohols-as-the-weak-eluent-in-hydrophilic-interaction-liquid-chromatography
#7
Jianfeng Cai, Lingping Cheng, Jianchao Zhao, Qing Fu, Yu Jin, Yanxiong Ke, Xinmiao Liang
A hydrophilic interaction liquid chromatography (HILIC) stationary phase was prepared by a two-step synthesis method, immobilizing polyacrylamide on silica sphere particles. The stationary phase (named PA, 5μm dia) was evaluated using a mixture of carbohydrates in HILIC mode and the column efficiency reached 121,000Nm(-1). The retention behavior of carbohydrates on PA stationary phase was investigated with three different organic solvents (acetonitrile, ethanol and methanol) employed as the weak eluent. The strongest hydrophilicity of PA stationary phase was observed in both acetonitrile and methanol as the weak eluent, when compared with another two amide stationary phases...
October 4, 2017: Journal of Chromatography. A
https://www.readbyqxmd.com/read/29029057/patient-specific-modelling-of-regional-tobramycin-concentration-levels-in-airways-of-patients-with-cystic-fibrosis-can-we-dose-once-daily
#8
Aukje C Bos, Johan W Mouton, Mireille van Westreenen, Eleni-Rosalina Andrinopoulou, Hettie M Janssens, Harm A W M Tiddens
Background: Inhaled tobramycin is important in the treatment of Pseudomonas aeruginosa ( Pa ) infections in cystic fibrosis (CF). However, despite its use it fails to attenuate the clinical progression of CF lung disease. The bactericidal efficacy of tobramycin is known to be concentration-dependent and hence changing the dosing regimen from a twice-daily (q12h) inhalation to a once-daily (q24h) inhaled double dose could improve treatment outcomes. Objectives: To predict local concentrations of nebulized tobramycin in the airways of patients with CF, delivered with the small airway-targeting Akita ® system or standard PARI-LC ® Plus system, with different inspiratory flow profiles...
September 23, 2017: Journal of Antimicrobial Chemotherapy
https://www.readbyqxmd.com/read/29028252/surveillance-and-analysis-of-occupational-carbon-monoxide-poisoning-in-the-paris-region
#9
Eric Dos Santos, Antoine Villa, Robert Garnier, Laurene Dufayet, Jerome Langrand
Objectives: Acute carbon monoxide poisoning is common and often severe. Domestic causes have been extensively documented, while occupational exposures have been reported less frequently. We analyse occupational carbon monoxide poisonings from the available data of the carbon monoxide poisoning surveillance network for Paris and its region, and identify predictive factors of severity for occupational poisoning in order to identify priority prevention actions. Methods: We retrospectively reviewed all events of acute accidental carbon monoxide exposures which occurred in the Paris region, at the work place, and notified to the surveillance network from 1 January 2005 to 31 December 2011...
October 1, 2017: Annals of Work Exposures and Health
https://www.readbyqxmd.com/read/29028105/value-of-confocal-laser-endomicroscopy-in-the-diagnosis-of-vocal-cord-lesions
#10
M Goncalves, H Iro, A Dittberner, A Agaimy, C Bohr
OBJECTIVE: The aim of this study was to assess the reliability and limitations of confocal laser endomicroscopy (CLE) for diagnosing lesions of the vocal cords and differentiating malignant from non-malignant lesions. PATIENTS AND METHODS: During microlaryngoscopy, the vocal cords were scanned by probe-based CLE (pCLE: a GastroFlex probe with the Cellvizio® laser system, Mauna Technologies, Paris, France). The video recordings were analyzed and compared with the histological results...
September 2017: European Review for Medical and Pharmacological Sciences
https://www.readbyqxmd.com/read/29027996/aquatic-urban-ecology-at-the-scale-of-a-capital-community-structure-and-interactions-in-street-gutters
#11
Vincent Hervé, Boris Leroy, Albert Da Silva Pires, Pascal Jean Lopez
In most cities, streets are designed for collecting and transporting dirt, litter, debris, storm water and other wastes as a municipal sanitation system. Microbial mats can develop on street surfaces and form microbial communities that have never been described. Here, we performed the first molecular inventory of the street gutter-associated eukaryotes across the entire French capital of Paris and the non-potable waters sources. We found that the 5782 OTUs (operational taxonomic units) present in the street gutters which are dominated by diatoms (photoautotrophs), fungi (heterotrophs), Alveolata and Rhizaria, includes parasites, consumers of phototrophs and epibionts that may regulate the dynamics of gutter mat microbial communities...
October 13, 2017: ISME Journal
https://www.readbyqxmd.com/read/29027983/to-facilitate-or-curb-the-role-of-financial-development-in-china-s-carbon-emissions-reduction-process-a-novel-approach
#12
Tiancai Xing, Qichuan Jiang, Xuejiao Ma
With the Paris Agreement coming into effect, China, as the largest CO₂ emitter in the world, will be facing greater pressure to reduce its carbon emissions. This paper discusses how to solve this issue from the perspective of financial development in China. Although many studies have analyzed its impact on carbon emissions, the conclusions are contradictory. A major criticism of the existing studies is the reasonability of the selection of appropriate indicators and panel estimation techniques. Almost all studies use only one or limited indicators to represent the financial development and ignore the cross-sectional dependence...
October 13, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/29027974/longitudinal-measurements-of-tarnished-plant-bug-hemiptera-miridae-susceptibility-to-insecticides-in-arkansas-louisiana-and-mississippi-associations-with-insecticide-use-and-insect-control-recommendations
#13
Katherine A Parys, Randall G Luttrell, Gordon L Snodgrass, Maribel Portilla, Josh T Copes
Concentration-response assays were conducted from 2008 through 2015 to measure the susceptibility of field populations of Lygus lineolaris (Palisot de Beauvois) from the Delta regions of Arkansas, Louisiana, and Mississippi to acephate, imidacloprid, thiamethoxam, permethrin, and sulfoxaflor. A total of 229 field populations were examined for susceptibility to acephate, 145 for susceptibility to imidacloprid, and 208 for susceptibility to thiamethoxam. Permethrin assays were conducted in 2014 and 2015 to measure levels of pyrethroid resistance in 44 field populations, and sulfoxaflor assays were conducted against 24 field populations in 2015...
October 13, 2017: Insects
https://www.readbyqxmd.com/read/29024574/effects-of-plasma-jet-dielectric-barrier-discharge-photodynamic-therapy-and-sodium-hypochlorite-on-infected-curved-root-canals
#14
Husam Ballout, Moritz Hertel, Jonas Doehring, Eckehard Kostka, Stefan Hartwig, Sebastian Paris, Saskia Preissner
The aim of this investigation was to evaluate the effects of two different cold atmospheric plasma (CAP) sources, photodynamic therapy and sodium hypochlorite (NaOCl), on infected root canals. Therefore, 50 standardized curved human root canals were infected with Enterococcus faecalis and assigned to five groups - negative control (NC), plasma jet (CAP I), dielectric barrier discharge (CAP II), photodynamic therapy (PDT), and NaOCl + PUI - for 30 s. Colony forming units (CFUs) were determined. NaOCl was significantly more effective at reducing CFUs than all test groups (p < ...
October 12, 2017: Journal of Biophotonics
https://www.readbyqxmd.com/read/29021735/quantifying-adsorption-induced-deformation-of-nanoporous-materials-on-different-length-scales
#15
Roland Morak, Stephan Braxmeier, Lukas Ludescher, Florian Putz, Sebastian Busch, Nicola Hüsing, Gudrung Reichenauer, Oskar Paris
A new in situ setup combining small-angle neutron scattering (SANS) and dilatometry was used to measure water-adsorption-induced deformation of a monolithic silica sample with hierarchical porosity. The sample exhibits a disordered framework consisting of macropores and struts containing two-dimensional hexagonally ordered cylindrical mesopores. The use of an H2O/D2O water mixture with zero scattering length density as an adsorptive allows a quantitative determination of the pore lattice strain from the shift of the corresponding diffraction peak...
October 1, 2017: Journal of Applied Crystallography
https://www.readbyqxmd.com/read/29020660/identification-of-twenty-nine-novel-germline-unclassified-variants-of-brca1-and-brca2-genes-in-1400-italian-individuals
#16
Concetta Santonocito, Margherita Scapaticci, Donatella Guarino, Andrea Bartolini, Angelo Minucci, Paola Concolino, Giovanni Scambia, Ida Paris, Ettore Capoluongo
OBJECTIVES: Breast and/or ovarian cancers are complex multifactorial diseases caused by interaction of both genetic and non-genetic factors and characterized by predisposition to inheritance. BRCA1 and BRCA2 genes are the most clinically involved with these kinds of cancer and the spectrum of variants affecting these genes is very wide. In fact, point variants, large or small insertions/deletions, genomic rearrangements can be found in these patients, although a large number of variants with uncertain biological and clinical significance continues to be identified...
October 8, 2017: Breast: Official Journal of the European Society of Mastology
https://www.readbyqxmd.com/read/29019353/hot-news-ready-for-hiv-dual-therapy-new-data-from-international-hiv-aids-society-2017
#17
George A Yendewa, Robert A Salata
The introduction of combination antiretroviral therapy (ART) in the 1990s has fundamentally transformed the landscape of HIV medicine, greatly improved disease morbidity and mortality, and reduced transmission rates across all demographic groups. Central to this success was the idea that to achieve best disease outcomes and minimize the development of drug resistance, at least three antiretroviral agents should be used for HIV treatment. This therapeutic strategy is a core tenet of HIV medicine, backed by incontrovertible scientific evidence, and made easy to deploy by the high compliance levels with once-daily coformulations, which have generally been well tolerated...
October 11, 2017: AIDS Reviews
https://www.readbyqxmd.com/read/29019351/hot-news-exosomes-as-new-players-in-hiv-pathogenesis-new-data-from-the-ias-2017
#18
Eva Poveda, Michael L Freeman
Exosomes are nanovesicles that can be released into the extracellular medium by different cell types and are considered an important system of intercellular communication. In some instances, on secretion, exosomes break down and release their content into the extracellular space. Alternatively, intact exosomes can interact with other cells and discharge their content directly into the target cell cytoplasm. Exosomes are rich in endosome-associated proteins (i.e., the tetraspanin family) but also carry different molecules in their lumen including proteins, RNAs (i...
October 11, 2017: AIDS Reviews
https://www.readbyqxmd.com/read/28993294/structural-elucidation-and-antiaging-activity-of-polysaccharide-from-paris-polyphylla-leaves
#19
Shian Shen, Zhou Xu, Shiling Feng, Handong Wang, Jing Liu, Lijun Zhou, Ming Yuan, Yan Huang, Chunbang Ding
To optimize the use of Paris polyphylla resources, a homogenous polysaccharide (PPLP) was obtained from P. polyphylla leaves. Its average molecule weight was 2.95×10(4)Da, and the analysis of monosaccharide composition shown that PPLP consisted of l-arabinose and d-galactose with a molar ratio of 4.2:5.8. Methylation and nuclear magnetic resonance (NMR) spectroscopy data revealed that the backbone of PPLP was comprised of (1→6)-β-d-galactan, and the branched chains mainly consisted of arabinosyl residues which was linked to backbone via (1→3)-linkages...
October 6, 2017: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/28989288/a-family-of-early-english-oculists-1600-1751-with-a-reappraisal-of-john-thomas-woolhouse-1664-1733-1734
#20
REVIEW
Christopher T Leffler, Stephen G Schwartz
INTRODUCTION: John Thomas Woolhouse (1666-1733/1734), who practiced in Paris, was part of a family with 5 generations of English oculists. Some historians have derided him as a "charlatan" and have criticized him for adhering to the old notion that a cataract was a membrane anterior to the lens. METHODS: We reviewed treatises and digital records related to Woolhouse and his family and the handwritten notes of his 1721 lecture series at the Royal Society of Medicine...
2017: Ophthalmology and Eye Diseases
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