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dilated myocardiopathy

Xiaoyan Liu, Yanlin Zhu, Xue Lin, Ligang Fang, Xiaowei Yan
RATIONALE: Anthracyclines cardiotoxicity characterized by dilated myocardiopathy has been well described in the literature. However, anthracyclines-induced valvular diseases have been seldom reported. PATIENT CONCERNS: In this study, we present the case of a 62-year-old Chinese female patient with breast cancer developing severe mitral regurgitation after anthracycline exposure. DIAGNOSES: The patient was diagnosed with mitral regurgitation with preserved left ventricular ejection fraction and normal cardiac chamber dimensions in the sixth month after the last course of anthracycline-containing chemotherapy...
December 2017: Medicine (Baltimore)
Rongrong Sun, Jiangbo Wang, Yi Zheng, Xianchi Li, Tiantian Xie, Rui Li, Min Liu, Yong Cao, Lei Lu, Qing Zhang, Peiying Zhang
We investigated the effect of baoxin decoction (BXD) on myocardial fibrosis and clarified the possible mechanism of action. Dilated myocardiopathy was induced by doxorubicin injected intraperitoneally for 6 weeks. Rats that demonstrated dilated myocardiopathy were randomly divided into five groups plus a control group. Three groups were treated with BXD (7.5/kg, 15 g/kg and 30 g/kg) daily for 4 weeks. One group was treated with 8.75 g/kg of captopril (positive control), and with physiologic saline (negative control)...
May 2017: Experimental and Therapeutic Medicine
Virginia Delgado-Maroto, Clara P Falo, Irene Forte-Lago, Norma Adan, Maria Morell, Elena Maganto-Garcia, Gema Robledo, Francisco O'Valle, Andrew H Lichtman, Elena Gonzalez-Rey, Mario Delgado
BACKGROUND AND PURPOSE: Myocarditis is an inflammatory and autoimmune cardiovascular disease that causes dilated myocardiopathy and is responsible for high morbidity and mortality worldwide. Cortistatin is a neuropeptide produced by neurons and cells of the immune and vascular systems. Besides its action in locomotor activity and sleep, cortistatin inhibits inflammation in different experimental models of autoimmune diseases. However, its role in inflammatory cardiovascular disorders is unexplored...
February 2017: British Journal of Pharmacology
Paula Larrañaga-Fragoso, Natalia Pastora, Luciano Bravo-Ljubetic, Jesús Peralta, José Abelairas-Gómez
BACKGROUND: Alström syndrome is a rare genetic ciliopathy caused by a mutation in the ALMS1 gene. The syndrome is characterized by cone-rod dystrophy, dilated myocardiopathy, childhood obesity and sensorineural hearing loss. To date, cystoid macular edema has not been reported. METHODS: A female affected by Alström syndrome developed bilateral cystoid macular edema evidenced by optical coherence tomography. A topical carbonic anhydrase inhibitor was prescribed...
December 2016: Ophthalmic Genetics
Tadashi Isomura
No abstract text is available yet for this article.
June 2014: Kyobu Geka. the Japanese Journal of Thoracic Surgery
YouZhang Xiang, Qun Xu, WuHong Tan, ShuLan He, XiaoWei Shi, WenMing Zhang, Jing Wang, XiuHong Wang, WeiJuan Ma
The etiology of Keshan disease (KD), an endemic myocardiopathy in regions of China, is largely unknown. To show the protein changes in serum from KD patients versus controls and idiopathic dilated cardiomyopathy (IDCM) and to search specific biological markers for differential diagnosis for KD. Serum of 65 patients with KD was compared with 29 patients with IDCM, 62 controls from KD areas and 28 controls from non-KD areas by ClinProt/MALDI-ToF technique. The genetic algorithm, quick classifier algorithm and supervised neural network algorithm methods were used to screen marker proteins and establish diagnostic model...
August 2014: Protein Journal
M Cordeiro, F Scaglia, S Lopes Da Silva, P Garcia, M Grazina, C Moura, L Diogol
Mitochondrial respiratory chain disorders (MRCD) are a heterogeneous group of diseases leading to an inadequate production of ATP. Brain and heart are among the most affected organs. Thus far, no specific relationship has been found between specific affected areas in the central nervous system and cardiac involvement. This study investigated the relationship between specific brain involvement and heart disease in mitochondrial disorders. We hypothesize that specific areas of brain lesions in children with MRCD are more frequently correlated to heart disease than others...
December 14, 2009: Neuroradiology Journal
Nevenka Radić, Kristina Radinović, Mihailo Ille, Aleksandar Lesić, Stojanović Mirjana Ljubicić, Z Marko Bumbasirević
INTRODUCTION: Hip fracture is a pathological condition, more common in older age, i.e. in people over 65 years. The prevalence of this disorder is continuously increasing, simultaneously with higher age limit. In evaluation of risk for operation and anesthesia, older age itself represents higher risk and calls for special attention. In selection of anesthesiological technique, it is more usual to apply neuroaxial block or peripheral nerve block, which is more advantageous over general anesthesia...
2012: Acta Chirurgica Iugoslavica
Alexandre Braga Libório, Russian Soares Uchia, Alessa Peixoto Aragao, João David de Sousa Neto, Juan Miguel Cosquillo Valdivia, Filipe de Alencar, Ricardo Everton Dias Mont'Alverne, Francisco Ivan Benício de Sá Filho, Juan Alberto Cosquillo Mejia
BACKGROUND: Cardiorenal syndrome has been recently divided into 5 categories, according to acute or chronic evolution and primary organ dysfunction. Anemia can also accompany this disorder, leading to a more complex situation. This study aims to analyze the renal outcomes of patients, specifically patients with chronic Cardiorenal syndrome, with or without anemia, long-term after heart transplantation. MATERIAL/METHODS: This was a retrospective cohort study on chronic Cardiorenal syndrome patients submitted to heart transplantation...
October 2012: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
Adria Arboix, Josefina Alio
Cardioembolic cerebral infarction (CI) is the most severe subtype of ischaemic stroke but some clinical aspects of this condition are still unclear. This article provides the reader with an overview and up-date of relevant aspects related to clinical features, specific cardiac disorders and prognosis of CI. CI accounts for 14-30% of ischemic strokes; patients with CI are prone to early and long-term stroke recurrence, although recurrences may be preventable by appropriate treatment during the acute phase and strict control at follow-up...
February 2012: Current Cardiology Reviews
Lamia Hamdan, Muriel Bost, Guy Chazot, Bernard Bui-Xuan, Fanny Vaillant, Leila Dehina, Jacques Descotes, Alain Tabib, Zahida Mamou, Quadiri Timour
The involvement of psychotropic drugs in sudden deaths has been highlighted. The objective of this work was to establish a link between selenium levels in heart tissue, psychotropic treatment and sudden death. Selenium levels were measured by electrothermal atomic absorption spectroscopy post-mortem in heart, brain and liver. Histological examination evidenced dilated cardiomyopathy in 45% of cases, left ventricular hypertrophy in 36%, and ischemic coronaropathy in 18%. A significant reduction of myocardial selenium levels compared to controls was seen in patients treated with neuroleptic drugs or meprobamate...
June 2012: Journal of Trace Elements in Medicine and Biology
C M Holgado, S Coves
Haemodynamic changes that occur during pregnancy are maximal between 28 and 34 weeks. In the pregnant woman with several associated diseases, such as hypertensive myocardiopathy and pre-gestational diabetes, these changes can lead to a difficult control of pulmonary hypertension and acute pulmonary oedema. We report the case of a pregnant woman with long term type 1 diabetes mellitus who suffered pre-eclampsia in a previous pregnancy, and since then developed hypertensive cardiomyopathy. She was admitted at 30 week gestation for metabolic and blood pressure control, and developed congestive cardiac failure after the administration of betamethasone for foetal lung maturity...
February 2013: Revista Española de Anestesiología y Reanimación
Yoshitaka Ikeda, Hiroshi Kurazumi, Masafumi Sato, Ryo Suzuki, Bungo Shirasawa, Akihito Mikamo, Kimikazu Hamano
BACKGROUND: Surgical ventricular restoration (SVR) is considered as an effective surgical procedure for patients with ischemic myocardiopathy( ICM). However" surgical treatment for ischemic heart failure (STICH)" trial concluded that adding SVR to coronary artery bypass grafting (CABG) did not relieve symptoms and failed to lower death rate or cardiac rehospitalization as compared with CABG alone. AIM: The aim of this study was to investigate the efficacy of CABG with SVR for ICM...
February 2012: Kyobu Geka. the Japanese Journal of Thoracic Surgery
César Alducin-Téllez, Enrique Rueda-Villegas, Isaí Medina-Yerbes, Oscar Hernández, Ruth López, Virginia Peña-Hernández, Víctor Monteón
The prevalence of chronic Chagas' heart disease as a cause of dilated cardiomyopathy is unknown in the State of Campeche, Mexico. A study was conducted to determine the prevalence of positive serology for Trypanosoma cruzi in patients with clinical diagnosis of dilated cardiomyopathy. Of a total of 127 patients diagnosed with dilated cardiomyopathy, we studied 91 with two positive serological tests for T. cruzi. We identified 14 positive cases for a prevalence of 15 % of chronic Chagas' heart disease. This prevalence is similar to that reported for the rest of the Yucatan Peninsula...
July 2011: Archivos de Cardiología de México
Adrià Arboix, Josefina Alió
This article provides the reader with an overview and up-date of clinical features, specific cardiac disorders and prognosis of cardioembolic stroke. Cardioembolic stroke accounts for 14-30% of ischemic strokes and, in general, is a severe condition; patients with cardioembolic infarction are prone to early and long-term stroke recurrence, although recurrences may be preventable by appropriate treatment during the acute phase and strict control at follow-up. Certain clinical features are suggestive of cardioembolic infarction, including sudden onset to maximal deficit, decreased level of consciousness at onset, Wernicke's aphasia or global aphasia without hemiparesis, a Valsalva manoeuvre at the time of stroke onset, and co-occurrence of cerebral and systemic emboli...
August 2010: Current Cardiology Reviews
Noelia Vázquez Fuentes, José Javier Querol Gutiérrez, José María Miralles Ibarra, Rafael Merino de Torres, Juan Carlos Querol Gutiérrez, Enrique Manuel Laza Y Laza
Cardiovascular pathology is common in rheumatoid arthritis. However, myocardial affection is unusual and clinical disease is rare. We report a case of dilated cardiomyopathy in a patient with rheumatoid arthritis and progressive heart failure that required inclusion into a heart transplantation list.
July 2007: Reumatología Clinica
N Brogly, E Guasch, L Puertas, E Alsina, T López, F Gilsanz
The use of levosimendan (Simdax(®)) was described in cases of acute cardiac failure in patients with peripartum cardiopmyopathy. We report the case of a 36 years old Philippine woman with an undiagnosed dilated myocardiopathy. She developed an acute severe left ventricular dysfunction in the early postpartum period after a cesarean section, possibly related to the recurrence of an unknown peripartum myocardiopathy. Due to failure of the conventional treatment with diuretics and inotropic support, an intra-aortic balloon with counter-pulsation was inserted...
November 2010: Annales Françaises D'anesthèsie et de Rèanimation
A Sánchez Andrés, E Valdés Diéguez, A Marco Macián, J I Carrasco Moreno
Asymptomatic 2 month-old infant referred for evaluation of a hard abdominal mass on the left side. The ultrasound examination showed a solid-cystic tumour above the left kidney. The alpha-fetoprotein level was 2000ng/ml. The meta-iodobenzylguanidine (123-I-MIBG) showed no tumour uptake. At 48h, she showed signs of hypovolemic shock. The chest X-ray showed cardiomegaly with a cardiothoracic ratio of 0.7 and pulmonary congestion. The echocardiogram showed a dilated left ventricle with ejection fraction 35-40%...
December 2010: Anales de Pediatría: Publicación Oficial de la Asociación Española de Pediatría (A.E.P.)
Renzo Galanello, Raffaella Origa
Beta-thalassemias are a group of hereditary blood disorders characterized by anomalies in the synthesis of the beta chains of hemoglobin resulting in variable phenotypes ranging from severe anemia to clinically asymptomatic individuals. The total annual incidence of symptomatic individuals is estimated at 1 in 100,000 throughout the world and 1 in 10,000 people in the European Union. Three main forms have been described: thalassemia major, thalassemia intermedia and thalassemia minor. Individuals with thalassemia major usually present within the first two years of life with severe anemia, requiring regular red blood cell (RBC) transfusions...
May 21, 2010: Orphanet Journal of Rare Diseases
Ad Kane, M Mbaye, M B Ndiaye, M Diao, P-M Moreira, C Mboup, I B Diop, M Sarr, A Kane, J-C Moreau, S A Ba
UNLABELLED: The aims of this work are to study the nursery futures during idiopathic myocardiopathy of peripartum (IMPP), to measure the prevalence of thromboses and spontaneous contrast during the IMPP and to determine their evolution. METHODOLOGY: It is about a longitudinal exploratory study carried out with the Aristide-Le-Dantec teaching hospital of Dakar, beginning January 2001 to November 2004, having included 33 patients. RESULTS: The average age of the patients was 26 years; the average pregnancy was of 3...
October 2010: Journal de Gynécologie, Obstétrique et Biologie de la Reproduction
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