Emma T Margolis, Lauren Davel, Niall J Bourke, Cara Bosco, Michal R Zieff, Alexa D Monachino, Thandeka Mazubane, Simone R Williams, Marlie Miles, Chloë A Jacobs, Sadeeka Williams, Layla Bradford, Candice Knipe, Zamazimba Madi, Bokang Methola, Tembeka Mhlakwaphalwa, Nwabisa Mlandu, Khanyisa Nkubungu, Zayaan Goolam Nabi, Tracy Pan, Reese Samuels, Nicolò Pini, Vanja Klepac-Ceraj, William P Fifer, Daniel C Alexander, Derek K Jones, Steve C R Williams, Dima Amso, Kirsten A Donald, Laurel J Gabard-Durnam
Prenatal alcohol exposure (PAE) affects neurodevelopment in over 59 million individuals globally. Prior studies using dichotomous categorization of alcohol use and comorbid substance exposures provide limited knowledge of how prenatal alcohol specifically impacts early human neurodevelopment. In this longitudinal cohort study from Cape Town, South Africa, PAE is measured continuously-characterizing timing, dose, and drinking patterns (i.e., binge drinking). High-density electroencephalography (EEG) during a visual-evoked potential (VEP) task was collected from infants aged 8 to 52 weeks with prenatal exposure exclusively to alcohol and matched on sociodemographic factors to infants with no substance exposure in utero...
March 21, 2024: Developmental Psychology