keyword
https://read.qxmd.com/read/37681357/adherence-of-parp-inhibitor-for-frontline-maintenance-therapy-in-primary-epithelial-ovarian-cancer-a-cross-sectional-survey
#21
JOURNAL ARTICLE
Ji Hyun Kim, Yumi Lee, Da-Young Kim, Sinae Kim, Sang-Soo Seo, Sokbom Kang, Sang-Yoon Park, Myong Cheol Lim
OBJECTIVE: To identify the adherence rate to poly (ADP-ribose) polymerase (PARP) inhibitors and identify factors contributing to the deterioration of adherence at our institution. METHODS: The adherence rate to PARP inhibitors was calculated using self-reported Adherence to Refills and Medications Scale questionnaires from a cross-sectional survey. Multivariable logistic regression analysis was performed to identify the factors that affected adherence. RESULTS: Of the 131 respondents, 32 (24...
September 5, 2023: Journal of Gynecologic Oncology
https://read.qxmd.com/read/37668931/current-status-of-the-educational-environment-to-acquire-and-maintain-the-professional-skills-of-radiotherapy-technology-and-medical-physics-specialists-in-japan-a-nationwide-survey
#22
JOURNAL ARTICLE
Naoki Hayashi, Masahiko Okumura, Mitsuhiro Nakamura, Yoshitomo Ishihara, Seiichi Ota, Naoki Tohyama, Kohei Shimomura, Hiroyuki Okamoto, Hiroshi Onishi
This study aimed to investigate the educational environment of radiotherapy technology and medical physics specialists (RTMP) in Japan. We conducted a nationwide questionnaire survey in radiotherapy institutions between June and August 2022. Participants were asked questions regarding the educational system, perspectives on updating RTMP's skills and qualifications, and perspectives on higher education for RTMP at radiotherapy institutions. The results were then analyzed in detail according to three factors: whether the hospital was designed for cancer care, whether it was a Japanese Society for Radiation Oncology (JASTRO)-accredited hospital, and whether it was an intensity-modulated radiation therapy charged hospital...
December 2023: Radiological Physics and Technology
https://read.qxmd.com/read/37664353/prevalence-of-depression-and-anxiety-disorders-among-cancer-patients-an-insight-from-a-single-institute
#23
JOURNAL ARTICLE
Remya Radhakrishnan, Hemalatha Selvaraj, Kumarappan Chidambaram, Arshav Kv, Adona James, Sivakumar Thangavel
Objective This cross-sectional, observational study aimed at finding the prevalence of anxiety and depression in cancer patients and the correlation of anxiety and depression with various factors, such as age, sex, marital status, educational status, occupation, financial support, duration, type of care, sort of carcinoma, and stages of malignancy, among cancer patients attending the G. Kuppuswamy Naidu Memorial Hospital, Coimbatore, Tamil Nadu, India from July 2022 to December 2022, using the Hospital Anxiety and Depression Scale (HADS)...
August 2023: Curēus
https://read.qxmd.com/read/37638461/factors-contributing-to-financial-distress-in-young-adults-with-cancer-material-resources-health-and-workplace
#24
JOURNAL ARTICLE
Rhonda Robert, Clark R Andersen, Kathleen M Murphy, Teresa A Granger, Melissa C Scardaville, Sandra A Medina-George, Vinh Nguyen, Lex M Frieden
BACKGROUND: Financial distress is a primary concern for young adults with cancer. OBJECTIVE: The aim of this study was to identify material resources, physical and psychological health, and workplace variables that are associated with financial distress in young adult cancer survivors. METHODS: A cross-sectional study was conducted using the Cancer Survivor Employment Needs Survey. Participants were young adults (18-39 years of age) who lived in the United States and had a cancer diagnosis...
August 20, 2023: Work: a Journal of Prevention, Assessment, and Rehabilitation
https://read.qxmd.com/read/37625436/making-meaning-of-everyday-life-in-the-context-of-lung-cancer-treatment-a-qualitative-study-of-outpatients-perspectives
#25
JOURNAL ARTICLE
Maria Bensen Joensen, Line Lindahl-Jacobsen, Marianne Lindahl, Jesper Larsen Maersk
BACKGROUND: The increasing survival after a lung cancer diagnosis implies that patients live longer with the disease, which means that symptoms and side effects of the treatment become part of everyday life. AIM: The study explored how older adults make meaning of everyday life when undergoing treatment for their lung cancer. MATERIAL AND METHODS: A qualitative study using semi-structured interviews was conducted with 12 older adults with lung cancer undergoing various treatments...
August 25, 2023: Scandinavian Journal of Occupational Therapy
https://read.qxmd.com/read/37615435/feasibility-of-optimal-a-self-management-programme-for-oesophageal-cancer-survivors
#26
JOURNAL ARTICLE
Eilish King, Naomi Algeo, Deirdre Connolly
INTRODUCTION: There is limited availability of self-management interventions for oesophageal cancer survivors at present. This study examined the feasibility of OptiMal, a six-week, self-management programme to improve fatigue, mood and health-related quality of life for oesophageal cancer survivors. METHODS: A mixed methods design was used to evaluate the feasibility of OptiMal. The quantitative arm of the study examined changes in the Multidimensional Fatigue Inventory, Hospital Anxiety and Depression Scale, and the EQ-5D-3L, administered prior to OptiMal (T1), immediately following completion of OptiMal (T2), and three months following completion (T3)...
2023: Cancer Control: Journal of the Moffitt Cancer Center
https://read.qxmd.com/read/37564928/involvement-in-treatment-decision-making-and-self-reported-efficacy-among-patients-with-advanced-colorectal-cancer-a-nationwide-multi-center-cross-sectional-study
#27
JOURNAL ARTICLE
Xiao-Fen Gu, Hui-Fang Xu, Yin Liu, Li Li, Yan-Qin Yu, Xi Zhang, Xiao-Hui Wang, Wen-Jun Wang, Ling-Bin Du, Shuang-Xia Duan, He-Lu Cao, Yu-Qian Zhao, Yun-Yong Liu, Juan-Xiu Huang, Ji Cao, Yan-Ping Fan, Chang-Yan Feng, Xue-Mei Lian, Jing-Chang Du, Remila Rezhake, Li Ma, You-Lin Qiao
INTRODUCTION: This cross-sectional study evaluated the involvement of patients with advanced colorectal cancer (CRC) in treatment decision-making, assessed the treatment efficacy according to their self-reports, and investigated the influencing factors. METHODS: Patients with advanced CRC were recruited from 19 hospitals from March 2020 to March 2021 by a multi-stage multi-level sampling method. A self-designed questionnaire was used to collect demographic and clinical characteristics, involvement of CRC patients in treatment decision-making, treatment methods, and self-reported efficacy...
2023: Frontiers in Oncology
https://read.qxmd.com/read/37560342/assessing-adherence-to-adjuvant-hormone-therapy-in-breast-cancer-patients-in-routine-clinical-practice
#28
JOURNAL ARTICLE
Natalia Camejo, Cecilia Castillo, Clara Tambasco, Noelia Strazzarino, Nicolas Requena, Silvina Peraza, Anna Boronat, Guadalupe Herrera, Patricia Esperon, Mauricio Cuello, Gabriel Krygier
BACKGROUND: Adjuvant hormone therapy (HT) in patients with hormone receptor-positive breast cancer (BC) increases overall survival (OS). A lack of adherence to adjuvant endocrine therapy is common, 31.0-73.0% of women discontinue endocrine treatment before 5 years. The aim of the study was to assess adherence to HT in routine clinical practice in patients assisted at the Clinical Oncology Department of the Hospital de Clinicas - Universidad de la Republica, Uruguay. METHODS: Patients treated with HT for stage 0-III BC between 2017 and 2019 were included...
August 2023: World Journal of Oncology
https://read.qxmd.com/read/37541272/radiotherapy-resources-in-brazil-rt2030-a-comprehensive-analysis-and-projections-for-2030
#29
REVIEW
Arthur Accioly Rosa, Cecília Félix Penido Mendes de Sousa, Leonardo Cunha Furbino Pimentel, Homero Lavieri Martins, Fabio Ynoe Moraes, Gustavo Nader Marta, Marcus Simões Castilho
BACKGROUND: The demand for radiotherapy in Brazil is unfulfilled, and the scarcity of data on the national network hampers the development of effective policies. We aimed to evaluate the current situation, estimate demands and requirements, and provide an action plan to ensure access to radiotherapy for those in need by 2030. METHODS: The Brazilian Society for Radiation Oncology created a task force (RT2030) including physicians, medical physicists, policy makers, patient advocates, and suppliers, all of whom were major stakeholders involved in Brazilian radiotherapy care...
August 2023: Lancet Oncology
https://read.qxmd.com/read/37507802/novel-covalent-cdk7-inhibitor-potently-induces-apoptosis-in-acute-myeloid-leukemia-and-synergizes-with-venetoclax
#30
JOURNAL ARTICLE
Tarang Gaur, Ramulu Poddutoori, Leena Khare, Bhausaheb Bagal, Sonal Rashmi, Nikhil Patkar, Prashant Tembhare, Subramanian Pg, Dhanlaxmi Shetty, Amit Dutt, Qi Zhang, Marina Konopleva, Uwe Platzbeckar, Sudeep Gupta, Susanta Samajdar, Murali Ramchandra, Navin Khattry, Syed K Hasan
INTRODUCTION: The emergence of resistance to the highly successful BCL2-directed therapy is a major unmet need in acute myeloid leukemia (AML), an aggressive malignancy with poor survival rates. Towards identifying therapeutic options for AML patients who progress on BCL2-directed therapy, we studied a clinical-stage CDK7 inhibitor XL102, which is being evaluated in solid tumors (NCT04726332). MATERIALS AND METHODS: To determine the anti-proliferative effects of XL102, we performed experiments including time-resolved fluorescence resonance energy transfer, target occupancy, cell cycle and apoptosis-based assays...
July 29, 2023: Journal of Experimental & Clinical Cancer Research: CR
https://read.qxmd.com/read/37504363/abstract-proceedings-of-the-38th-annual-canadian-association-of-psychosocial-oncology-capo-conference-june-2023
#31
Peter Traversa, Carmen G Loiselle
On behalf of the Canadian Association of Psychosocial Oncology, we are pleased to present the Abstracts from the 2023 Annual Conference, titled "Co-designing Psychosocial Oncology: Optimizing Outcomes for All". The conference was held in Montreal from 20 June 2023 to 22 June 2023. This conference brought together key stakeholders including multidisciplinary professionals from nursing, psychology, psychiatry, social work, spiritual care, nutrition, medicine, rehabilitation medicine, occupational health and radiation therapy for both adult and pediatric populations...
July 20, 2023: Current Oncology
https://read.qxmd.com/read/37504321/feasibility-and-implementation-of-an-oncology-rehabilitation-triage-clinic-assessing-rehabilitation-exercise-need-and-triage-pathways-within-the-alberta-cancer-exercise-neuro-oncology-study
#32
JOURNAL ARTICLE
Lauren C Capozzi, Julia T Daun, George J Francis, Marie de Guzman Wilding, Gloria Roldan Urgoiti, David Langelier, Nicole Culos-Reed
Individuals living with and beyond cancer face physical impairment and inactivity in survivorship. Neuro-oncology populations have especially high rates of sedentary behaviour and functional deficits, including impaired balance, motor skills, and cognition. Our purpose was to assess the rehabilitation and exercise needs of patients with brain tumours while examining the feasibility of a rehabilitation triage clinic as a part of the Alberta Cancer Exercise-Neuro-Oncology study, where patients were referred to a triage clinic, where health, neurologic, and functional status was assessed, followed by a referral to one or multiple resources, including exercise, physiotherapy, occupational therapy, or physiatry...
June 28, 2023: Current Oncology
https://read.qxmd.com/read/37382847/building-a%C3%A2-screen-for-cancer-survivorship-occupational-therapy-services-socs-ots-a-classical-delphi-study
#33
JOURNAL ARTICLE
Katie M Polo, Jordan Romero, Daria Seccurro, Kenzie Salzbrenner, Taylor Henson, Michael Wroblewski, Shanele Tyler
PURPOSE: The purpose of this study was to develop and validate items for the Screen of Cancer. Survivorship - Occupational Therapy Services (SOCS-OTS), a patient-driven screening tool to be used by frontline workers and filled out by cancer survivors that can indicate a need for appropriate occupational therapy (OT) referral. METHODS: Five rounds of a classical Delphi study were conducted to determine item inclusion. Expert panelists in rounds 1 and 2 consisted of adults LWBC who verified proposed items relevant to issues in activities of daily living (ADLs)...
June 29, 2023: Journal of Cancer Survivorship: Research and Practice
https://read.qxmd.com/read/37355925/tailored-support-for-preparing-employees-with-cancer-to-return-to-work-recognition-and-gaining-new-insights-in-an-open-atmosphere
#34
JOURNAL ARTICLE
Corine M Tiedtke, Roland W B Blonk, Willem Van Rhenen, Martine Van Egmond, Margot C W Joosen
BACKGROUND: A considerable number of cancer survivors face difficulties in returning to work (RTW). More insight is needed on how to support employees shortly after cancer treatment and help them make the transition back to work. OBJECTIVE: To gain an in-depth understanding of how and under what circumstances a Cancer & Work Support (CWS) program, which assists sick-listed employees with cancer in preparing their RTW, works. METHODS: A qualitative design was used, inspired by Grounded Theory and Realist Evaluation components...
June 23, 2023: Work: a Journal of Prevention, Assessment, and Rehabilitation
https://read.qxmd.com/read/37354019/preferences-for-participation-measurement-among-individuals-diagnosed-with-cancer-a-qualitative-content-analysis
#35
JOURNAL ARTICLE
Allison J L'Hotta, Taniya E Varughese, Kathleen D Lyons, Audrey Trebelhorn, Annamayil Manohar, Allison A King
Individuals with cancer experience occupational participation restrictions, but there is no consensus on how to measure this construct. The objective of this study is to describe the perspectives and preferences of individuals with cancer regarding participation measurement. Forty individuals with brain, breast, colorectal, and lung cancer provided feedback on three participation measures in semi-structured interviews. Through an iterative, team-based content analysis approach, interview text was coded using the study codebook and organized into themes...
June 24, 2023: OTJR: Occupation, Participation and Health
https://read.qxmd.com/read/37346025/-cow-colostrum-component-composition-biological-properties-and-application-practice
#36
JOURNAL ARTICLE
S V Kuzmin, V N Rusakov, O O Sinitsyna, S G Myzel, V A Aleshkin
Bovine colostrum (ВС) has a high biological value, which allows it to be used for the development of new functional products. The aim of the study was to assess the possibility of using BC for the prevention and treatment of infectious and non-infectious diseases. Material and methods . The search for scientific information on the study of the component composition, immunobiological properties and the use of BC in clinical practice was carried out using the databases of the RSCI, CyberLeninka, ScienceDirect, PubMed...
2023: Voprosy Pitaniia
https://read.qxmd.com/read/37277820/estimation-of-the-value-of-curative-therapies-in-oncology-a-willingness-to-pay-study-in-china
#37
JOURNAL ARTICLE
Li Huang, Xiaochen Peng, Lihua Sun, Dawei Zhang
The objective of this study was to estimate the willingness to pay (WTP) per quality-adjusted life year (QALY) among people with malignancies in China. The WTP for a QALY was estimated using a contingent valuation survey. Health utility was measured in EuroQol-5 dimensions (EQ-5D). The questionnaires were completed in face-to-face interviews. Respondents consisted of patients with malignant tumors and their family members and came from three tertiary hospitals in different cities with high, medium, and low gross domestic product (GDP) levels...
June 5, 2023: Cost Effectiveness and Resource Allocation: C/E
https://read.qxmd.com/read/37271728/experience-and-acceptability-of-a-carer-focussed-intervention-in-acute-oncology-settings-a-qualitative-study-of-people-with-advanced-cancer-and-their-carers
#38
JOURNAL ARTICLE
Celia Marston, Deidre D Morgan, Jennifer Philip, Meera R Agar
OBJECTIVES: Providing optimal support for carers of people with advanced cancer is critical to facilitating discharge home from hospital. Carer Support Needs Assessment Tool-Intervention (CSNAT-I) has shown promise in supporting carers' needs in this context. This study aimed to explore patient and carers experiences with and views on the acceptability of the CSNAT-I delivered by occupational therapists in an acute oncology setting. METHODS: People with advanced cancer and their carers who had previously received the CSNAT-I as part of usual care while admitted to an Australian specialist cancer centre or acute hospital were invited to participate in interviews exploring their perceptions of the intervention...
June 4, 2023: Australian Occupational Therapy Journal
https://read.qxmd.com/read/37205203/case-report-pancreatic-and-hepatic-kaposiform-hemangioendothelioma-presenting-as-consumptive-coagulopathy-and-right-hepatic-atrophy
#39
Chengbo Ai, Tong Qiu, Jiangyuan Zhou, Chuan Wang, Jiulin Song, Siyu Pu, Shuguang Jin
Kaposiform hemangioendothelioma (KHE) is a rare vascular tumor that causes progressive angiogenesis and lymphangiogenesis, which often occurs in the skin or soft tissue, with an acute onset and rapid progression. A 4-year-old girl was admitted to our hospital with a 2-year history of thrombocytopenia, combined with right hepatic atrophy and pancreatic lesion for 3 months. At the age of two, she developed purpura and thrombocytopenia was detected, after treatment with gamma globulin and corticosteroids, the platelet count normalized, but it dropped immediately at lower doses...
2023: Frontiers in Oncology
https://read.qxmd.com/read/37122065/the-impact-of-cancer-relapse-and-poor-patient-outcomes-on-health-care-providers-practicing-in-the-oncology-field
#40
JOURNAL ARTICLE
Abdulrahman Alwhaibi, Miteb Alenazi, Bana Almadi, Nora Aljabali, Sahar Alkhalifah, Wajid Syed, Reem Alsaif, Salmeen D Bablghaith, Mohammed N Al-Arifi
INTRODUCTION: Devastating cancer-related events are not uncommon, and these events have weakened communication performance and induced stress among health care providers (HCPs), particularly physicians. This study aimed to investigate the perspective of HCPs emotionally affected by poor clinical outcomes due to the failure of cancer therapy. METHODS: A cross-sectional, online survey was conducted over 3 months among HCPs practicing in the field of oncology in Saudi Arabia, comprising physicians, pharmacists, and nurses...
2023: Cancer Control: Journal of the Moffitt Cancer Center
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