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https://www.readbyqxmd.com/read/29651955/increases-in-peripheral-systolic-pressure-levels-and-z-score-associate-gradual-aortic-pressure-increase-and-functional-arterial-impairment-in-children-and-adolescents
#1
Yanina Zocalo, Mariana Marin, Santiago Curcio, Victoria Garcia-Espinosa, Pedro Chiesa, Gustavo Giachetto, Edmundo I Cabrera-Fischer, Daniel Bia
BACKGROUND: Arterial changes associated with children and adolescents high blood pressure (HBP) states would vary depending on the arterial type, arterial indexes considered and/or on blood pressure (BP) levels. AIMS: To determine in children and adolescents: 1) if there is gradual structural-functional arterial impairment associated with gradual peripheral (brachial) systolic BP (pSBP) level or z-score increases, and 2) whether subjects with HBP levels and those with normal BP differ in the profiles of arterial changes associated with pSBP deviations...
April 13, 2018: Current Hypertension Reviews
https://www.readbyqxmd.com/read/29524382/location-of-the-extrinsic-subunit-psbp-in-photosystem-ii-studied-by-pulsed-electron-electron-double-resonance
#2
Mizue Asada, Taishi Nishimura, Kentaro Ifuku, Hiroyuki Mino
The binding site of the extrinsic protein PsbP in plant photosystem II was mapped by pulsed electron-electron double resonance, using mutant spinach PsbP (Pro20Cys, Ser82Cys, Ala111Cys, and Ala186Cys) labeled with 4-maleimido-TEMPO (MSL) spin label. The distances between the spin label and the Tyr160 neutral radical (YD ) in PsbD, the D2 subunit of plant photosystem II, were 50.8 ± 3.5 Å, 54.9 ± 4.0 Å, 57.8 ± 4.9 Å, and 58.4 ± 14.1 Å, respectively. The geometry inferred from these distances was fitted to the PsbP crystal structure (PDB: 4RTI) to obtain the coordinates of YD relative to PsbP...
May 2018: Biochimica et Biophysica Acta
https://www.readbyqxmd.com/read/29486317/lumbosacral-intraspinal-paraganglioma-clinicopathologic-and-computed-tomography-magnetic-resonance-imaging-features-of-13-cases
#3
Xiaoping Yi, Youming Zhang, Chunhui Zhou, Guanghui Gong, Hongling Yin, Junjie Zeng, Longfei Liu, Weihua Liao, Xiaoyan Long
OBJECTIVE: To retrospectively review the clinicopathologic features and computed tomography (CT) and magnetic resonance imaging (MRI) findings of lumbosacral intraspinal paragangliomas (PGLs). METHODS: Thirteen patients with surgically and pathologically confirmed lumbosacral intraspinal PGLs were enrolled. Their clinicopathologic data and imaging findings were retrospectively reviewed. RESULTS: Ten male and 3 female patients with a median age of 43 years (range, 36-74 years) were included...
May 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29459745/joint-effect-of-non-invasive-central-systolic-blood-pressure-and-peripheral-systolic-blood-pressure-on-incident-hypertension-in-a-chinese-community-based-population
#4
Shixuan Wang, Zechen Zhou, Fangfang Fan, Litong Qi, Jia Jia, Pengfei Sun, Yimeng Jiang, Minghao Kou, Dafang Chen, Yan Zhang, Yong Huo
Central blood pressure level is not always consistent with peripheral blood pressure level, and especially their joint effect on incident hypertension is not well established. A total of 1607 non-hypertensive subjects from an atherosclerosis cohort in Beijing, China were included. Central systolic blood pressure (cSBP) was obtained using Omron HEM-9000AI machine and peripheral systolic blood pressure (pSBP) was measured using Omron HEM-7117 electronic sphygmomanometer, separately. Hypertension was defined as BP ≥ 140/90 mmHg or self-reported hypertension or taking any antihypertension drugs at the follow-up survey...
February 19, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29385615/orange-a-target-gene-for-regulating-carotenoid-homeostasis-and-increasing-plant-tolerance-to-environmental-stress-in-marginal-lands
#5
Ho Soo Kim, Chang Yoon Ji, Chan-Ju Lee, So-Eun Kim, Sung-Chul Park, Sang-Soo Kwak
Carotenoids play essential roles in various light-harvesting processes in plants and help protect the photosynthetic machinery from photo-oxidative damage. Orange genes, which play a role in carotenoid accumulation, were recently isolated from several plant species, and their functions were intensively investigated. The Orange gene (IbOr) from sweetpotato [Ipomoea batatas (L.) Lam] helps maintain carotenoid homeostasis to improve plant tolerance to environmental stress. IbOr, a protein with strong holdase chaperone activity, directly interacts with phytoene synthase (IbPSY), a key enzyme involved in carotenoid biosynthesis, in plants under stress conditions, resulting in increased carotenoid accumulation and abiotic stress tolerance...
January 27, 2018: Journal of Experimental Botany
https://www.readbyqxmd.com/read/29327917/peptide-based-photoelectrochemical-cytosensor-using-a-hollow-tio-2-eg-znin-2-s-4-cosensitized-structure-for-ultrasensitive-detection-of-early-apoptotic-cells-and-drug-evaluation
#6
Rong Wu, Gao-Chao Fan, Li-Ping Jiang, Jun-Jie Zhu
The ability to rapidly detect apoptotic cells and accurately evaluate therapeutic effects is significant in cancer research. To address this target, a biocompatible, ultrasensitive photoelectrochemical (PEC) cytosensing platform was developed based on electrochemically reduced graphene (EG)/ZnIn2 S4 cosensitized TiO2 coupled with specific recognition between apoptotic cells and phosphatidylserine-binding peptide (PSBP). In this strategy, the HL-60 cells were selected as a model and C005, nilotinib, and imatinib were selected as apoptosis inducers to show cytosensing performances...
February 7, 2018: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/29027293/determination-of-chemical-identity-and-occupancy-from-experimental-density-maps
#7
Jimin Wang
Three basic electronic properties of molecules, electron density (ED), charge density (CD), and electrostatic potentials (ESP), are dependent on both atomic mobility and occupancy of components in the molecules. Small protein subunits may bind large macromolecular complexes with a reduced occupancy or an increased atomic mobility or both due to affinity-based functional regulation, and so may substrates, products, cofactors, ions or solvent molecule to the active sites of enzymes. A quantitative theory is presented in this study that describes the dependence of atomic functions on atomic B-factor in Fourier transforms of the corresponding maps...
February 2018: Protein Science: a Publication of the Protein Society
https://www.readbyqxmd.com/read/28948506/comparative-analysis-of-arterial-parameters-variations-associated-with-inter-individual-variations-in-peripheral-and-aortic-blood-pressure-cross-sectional-study-in-healthy-subjects-aged-2-84-years
#8
COMPARATIVE STUDY
Yanina Zócalo, Santiago Curcio, Victoria García-Espinosa, Pedro Chiesa, Gustavo Giachetto, Daniel Bia
INTRODUCTION: The association between arterial parameters and blood pressure (BP) interindividual variations could depend on the arterial segment, BP component (systolic, SBP; diastolic, DBP; pulse pressure, PP) and/or on whether central (cBP) or peripheral (pBP) BP variations are considered. AIM: To assess and compare arterial parameters variations associated with interindividual variations in cBP and pBP. METHODS: Healthy subjects (n = 923; 488 males, 2-84 years) were included...
December 2017: High Blood Pressure & Cardiovascular Prevention: the Official Journal of the Italian Society of Hypertension
https://www.readbyqxmd.com/read/28895009/effect-of-different-methods-of-ca-2-extraction-from-psii-oxygen-evolving-complex-on-the-q-a-oxidation-kinetics
#9
Boris K Semin, Lira N Davletshina, Mahir D Mamedov
Lumenal extrinsic proteins PsbO, PsbP, and PsbQ of photosystem II (PSII) protect the catalytic cluster Mn4 CaO5 of oxygen-evolving complex (OEC) from the bulk solution and from soluble compounds in the surrounding medium. Extraction of PsbP and PsbQ proteins by NaCl-washing together with chelator EGTA is followed also by the depletion of Ca2+ cation from OEC. In this study, the effects of PsbP and PsbQ proteins, as well as Ca2+ extraction from OEC on the kinetics of the reduced primary electron acceptor (QA - ) oxidation, have been studied by fluorescence decay kinetics measurements in PSII membrane fragments...
April 2018: Photosynthesis Research
https://www.readbyqxmd.com/read/28870843/phosphatidylserine-a-cancer-cell-targeting-biomarker
#10
REVIEW
Bhupender Sharma, Shamsher S Kanwar
Cancer is a leading cause of mortality and morbidity globally. Many prominent cancer-associated molecules have been identified over the recent years which include EGFR, CD44, TGFbRII, HER2, miR-497, NMP22, BTA, Fibrin/FDP etc. These biomarkers are often used for screening, detection, diagnosis, prognosis, prediction and monitoring of cancer development. Phosphatidylserine (PS) is an essential component in all human cells which is present on the inner leaflet of the cell membrane. The oxidative stress causes exposure of PS on the surface of the vascular endothelium in the cancer cells (lung, breast, pancreatic, bladder, skin, brain metastasis, rectal adenocarcinoma etc...
September 1, 2017: Seminars in Cancer Biology
https://www.readbyqxmd.com/read/28798769/molecular-basis-underlying-leaf-variegation-of-a-moth-orchid-mutant-phalaenopsis-aphrodite-subsp-formosana
#11
Chi-Chu Tsai, Yu-Jen Wu, Chiou-Rong Sheue, Pei-Chun Liao, Ying-Hao Chen, Shu-Ju Li, Jian-Wei Liu, Han-Tsung Chang, Wen-Lin Liu, Ya-Zhu Ko, Yu-Chung Chiang
Leaf variegation is often the focus of plant breeding. Here, we studied a variegated mutant of Phalaenopsis aphrodite subsp. formosana, which is usually used as a parent of horticultural breeding, to understand its anatomic and genetic regulatory mechanisms in variegation. Chloroplasts with well-organized thylakoids and starch grains were found only in the mesophyll cells of green sectors but not of yellow sectors, confirming that the variegation belongs to the chlorophyll type. The two-dimensional electrophoresis and LC/MS/MS also reveal differential expressions of PsbP and PsbO between the green and yellow leaf sectors...
2017: Frontiers in Plant Science
https://www.readbyqxmd.com/read/28740096/associations-of-plasma-homocysteine-levels-with-peripheral-systolic-blood-pressure-and-noninvasive-central-systolic-blood-pressure-in-a-community-based-chinese-population
#12
Mohetaboer Momin, Fangfang Fan, Jianping Li, Xianhui Qin, Jia Jia, Litong Qi, Yan Zhang, Yong Huo
Previous studies indicated that homocysteine (Hcy) is associated with higher peripheral systolic blood pressure (pSBP). There have been few data on the relationship between Hcy and central SBP (cSBP). A total of 4,364 Chinese subjects from the Shijingshan community in Beijing were included. cSBP and pSBP were measured with an Omron HEM-9000AI device. Subjects were 57.20 ± 8.9 years old, 37.9% were male. The median of Hcy was 11.96 μmol/L. The mean of cSBP and pSBP was 129.94 ± 18.03 mmHg and 133...
July 24, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28642783/ibor-regulates-photosynthesis-under-heat-stress-by-stabilizing-ibpsbp-in-sweetpotato
#13
Le Kang, Ho S Kim, Young S Kwon, Qingbo Ke, Chang Y Ji, Sung-Chul Park, Haeng-Soon Lee, Xiping Deng, Sang-Soo Kwak
The Orange (Or) protein regulates carotenoid biosynthesis and environmental stress in plants. Previously, we reported that overexpression of the sweetpotato [Ipomoea batatas (L.) Lam] Or gene (IbOr) in transgenic Arabidopsis (referred to as IbOr-OX/At) increased the efficiency of photosystem II (PSII) and chlorophyll content after heat shock. However, little is known about the role of IbOr in PSII-mediated protection against abiotic stress. In this study, comparative proteomics revealed that expression of PsbP (an extrinsic subunit of PSII) is up-regulated in heat-treated IbOr-OX/At plants...
2017: Frontiers in Plant Science
https://www.readbyqxmd.com/read/28576401/-blood-pressure-values-in-adolescents-in-the-community-of-madrid-tables-based-on-the-mepafac-study
#14
A Molinero, M Cervero, M C Magro, T Partearroyo, P Zuluaga, A Martín
INTRODUCTION: High blood pressure (HBP) is a modifiable cardiovascular risk factor and its detection at early ages may allow strategies to be designed to reduce cardiovascular risk in adulthood. OBJECTIVES: To provide blood pressure (BP) values in a sample of adolescents using an electronic oscillometric device. MATERIAL AND METHODS: BP was measured according the European Society of Hypertension guidelines using an oscillometric device. Height and weight were also measured...
October 2017: Hipertensión y Riesgo Vascular
https://www.readbyqxmd.com/read/28534649/a-meta-analytical-comparison-of-atenolol-with-angiotensin-converting-enzyme-inhibitors-on-arterial-stiffness-peripheral-blood-pressure-and-heart-rate-in-hypertensive-patients
#15
REVIEW
Hong Xie, Gaoqing Luo, Yong Zheng, Feng Peng, Liangdi Xie
OBJECTIVES: This meta-analysis of randomized parallel controlled trials was designed to compare the efficacy of atenolol with angiotensin-converting enzyme inhibitors (ACEIs) in changing pulse wave velocity (PWV), peripheral blood pressure and heart rate (HR) among patients with essential hypertension. METHODS: This study was conducted according to the PRISMA guideline. Data collection was independently completed by two investigators. Statistical analyses were completed by Stata software (v12...
2017: Clinical and Experimental Hypertension: CHE
https://www.readbyqxmd.com/read/28523018/effect-of-azithromycin-in-combination-with-simvastatin-in-the-treatment-of-chronic-obstructive-pulmonary-disease-complicated-by-pulmonary-arterial-hypertension
#16
Peidong Wang, Jie Yang, Yanwei Yang, Zhixin Ding
OBJECTIVE: To evaluate the effect of azithromycin in combination with simvastatin in the treatment of chronic obstructive pulmonary disease (COPD) complicated by pulmonary arterial hypertension. METHODS: Eighty-six patients who developed COPD and pulmonary arterial hypertension and received treatment from August 2013 to October 2014 were selected and randomly divided into an observation group and a control group using random number table, 43 in each group. Patients in the control group were orally administrated 20 mg of simvastatin, once a day...
March 2017: Pakistan Journal of Medical Sciences Quarterly
https://www.readbyqxmd.com/read/28341915/in-vivo-system-for-analyzing-the-function-of-the-psbp-protein-using-chlamydomonas-reinhardtii
#17
Taishi Nishimura, Fumihiko Sato, Kentaro Ifuku
The PsbP protein is an extrinsic subunit of photosystem II (PSII) specifically developed in green-plant species including land plants and green algae. The protein-protein interactions involving PsbP and its effect on oxygen evolution have been investigated in vitro using isolated PSII membranes. However, the importance of those interactions needs to be examined at the cellular level. To this end, we developed a system expressing exogenous PsbP in the background of the Chlamydomonas BF25 mutant lacking native PsbP...
September 2017: Photosynthesis Research
https://www.readbyqxmd.com/read/28324975/quantification-of-peripheral-and-central-blood-pressure-variability-using-a-time-frequency-method
#18
Z Kouchaki, M Butlin, A Qasem, A P Avolio
Systolic blood pressure variability (BPV) is associated with cardiovascular events. As the beat-to-beat variation of blood pressure is due to interaction of several cardiovascular control systems operating with different response times, assessment of BPV by spectral analysis using the continuous measurement of arterial pressure in the finger is used to differentiate the contribution of these systems in regulating blood pressure. However, as baroreceptors are centrally located, this study considered applying a continuous aortic pressure signal estimated noninvasively from finger pressure for assessment of systolic BPV by a time-frequency method using Short Time Fourier Transform (STFT)...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28260335/-association-of-peripheral-and-central-systolic-blood-pressure-with-urinary-albumin-to-creatinine-ratio-in-a-community-based-population-in-beijing
#19
F F Fan, Y X Li, J Jia, H X Li, L T Qi, Y Huo, Y Zhang
Objective: The aim of this study was to investigate the association of both peripheral and central systolic blood pressure (pSBP and cSBP) with urinary albumin-to-creatinine ratio (UACR) in a community-based population in Beijing. Methods: A total of 3 479 Chinese subjects with questionnaire, UACR, pSBP, and cSBP data available were included from an atherosclerosis cohort of Peking University First Hospital in Shijingshan District, Beijing followed up from April to July in 2014. Multivariate linear regression analyses were used to examine the effect of pSBP and cSBP on lnUACR, and further tests for interactions were performed according to associated covariates...
March 6, 2017: Zhonghua Yu Fang Yi Xue za Zhi [Chinese Journal of Preventive Medicine]
https://www.readbyqxmd.com/read/28227135/quantification-of-peripheral-and-central-blood-pressure-variability-using-a-time-frequency-method
#20
Z Kouchaki, M Butlin, A Qasem, A P Avolio, Z Kouchaki, M Butlin, A Qasem, A P Avolio, Z Kouchaki, A P Avolio, M Butlin, A Qasem
Systolic blood pressure variability (BPV) is associated with cardiovascular events. As the beat-to-beat variation of blood pressure is due to interaction of several cardiovascular control systems operating with different response times, assessment of BPV by spectral analysis using the continuous measurement of arterial pressure in the finger is used to differentiate the contribution of these systems in regulating blood pressure. However, as baroreceptors are centrally located, this study considered applying a continuous aortic pressure signal estimated noninvasively from finger pressure for assessment of systolic BPV by a time-frequency method using Short Time Fourier Transform (STFT)...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
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