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https://www.readbyqxmd.com/read/29149147/hypothalamic-pituitary-adrenocortical-axis-suppression-following-a-single-epidural-injection-of-methylprednisolone-acetate
#1
Aleem Jameel Abdul, Babita Ghai, Dipika Bansal, Naresh Sachdeva, Anil Bhansali, Saravdeep Singh Dhatt
BACKGROUND: Epidural injections (EIs) are the most commonly performed minimally invasive intervention in managing chronic low back pain (CLBP). There is inconsistency in data to accurately predict the degree of hypothalamic-piuitary-adrenal (HPA) axis suppression in patients receiving exogenous steroid therapy, especially in the form of epidural steroid injections (ESIs). OBJECTIVE: We aim to quantify the degree and duration of HPA axis suppression after a single ESI of 80 mg methyl prednisolone acetate in patients with CLBP...
November 2017: Pain Physician
https://www.readbyqxmd.com/read/29140926/variability-in-negative-emotions-among-individuals-with-chronic-low-back-pain-relationships-with-pain-and-function
#2
James I Gerhart, John W Burns, Stephen Bruehl, David A Smith, Kristina M Post, Laura S Porter, Erik Schuster, Asokumar Buvanendran, Anne Marie Fras, Francis J Keefe
Chronic pain is associated with elevated negative emotions, and resources needed to adaptively regulate these emotions can be depleted during prolonged pain. Studies of links between pain, function and negative emotions in people with chronic pain, however, have focused almost exclusively on relationships among mean levels of these factors. Indexes that may reflect aspects of emotion regulation have typically not been analyzed. We propose that one index of emotion regulation is variability in emotion over time as opposed to average emotion over time...
November 13, 2017: Pain
https://www.readbyqxmd.com/read/29138049/pain-neurophysiology-education-and-therapeutic-exercise-for-patients-with-chronic-low-back-pain-a-single-blind-randomized-controlled-trial
#3
Bodes Pardo Gema, Lluch Girbés Enrique, Roussel Nathalie A, Gallego Izquierdo Tomás, Jiménez Penick Virginia, Pecos Martín Daniel
AIM: To assess the effect of a pain neurophysiology education program plus therapeutic exercise for patients with chronic low back pain (CLBP). DESIGN: Single-blind randomized controlled trial. SETTING: Private clinic (Clínica Bonn) and Alcalá de Henares University, Madrid, Spain. PARTICIPANTS: 56 patients with CLBP for 6 months or more. INTERVENTION: Participants were randomized to receive either a therapeutic exercise (TE) program consisting of motor control, stretching, and aerobic exercises (TE group, n=28) or the same therapeutic exercise program in addition to a pain neurophysiology education program (PNE+TE group, n=28), conducted in two 30 to 50 minute sessions in groups of 4 to 6 participants...
November 11, 2017: Archives of Physical Medicine and Rehabilitation
https://www.readbyqxmd.com/read/29125371/telerehabilitation-booster-sessions-and-remote-patient-monitoring-in-the-management-of-chronic-low-back-pain-a-case-series
#4
Seth Peterson
BACKGROUND: Improvements in chronic low back pain (CLBP) seen in physical therapy do not appear to be retained over the long term. Booster sessions have been proposed, but barriers exist to their implementation. Telerehabilitation (TR) and remote patient monitoring (RPM) may be ways to circumvent these barriers. The purpose of this case series was to describe the implementation of TR booster sessions and RPM in three patients with CLBP. CASE SERIES: Three females with CLBP tracked their daily pain level and home exercise program adherence using a mobile phone application for 12 months following discharge from traditional face-to-face physical therapy...
November 10, 2017: Physiotherapy Theory and Practice
https://www.readbyqxmd.com/read/29114517/effects-of-proprioceptive-neuromuscular-facilitation-based-abdominal-muscle-strengthening-training-on-pulmonary-function-pain-and-functional-disability-index-in-chronic-low-back-pain-patients
#5
Beom-Ryong Kim, Hye-Jin Lee
The purpose of this study was to evaluate the effect of abdominal muscle strengthening training (AMST) using proprioceptive neuromuscular facilitation (PNF) on pulmonary function, pain, and functional disability index in chronic low back pain (CLBP) patients. Thirty CLBP patients were randomly assigned to the traditional physical therapy (control) group (n=15) and PNF-AMST group (n=15). Forced expiratory volume at 1 second (FEV1) was measured to measure changes in pulmonary function. To measure the degree of pain, a visual analog scale (VAS) was used...
August 2017: Journal of Exercise Rehabilitation
https://www.readbyqxmd.com/read/29112155/efficacy-of-bee-venom-acupuncture-for-chronic-low-back-pain-a-randomized-double-blinded-sham-controlled-trial
#6
Byung-Kwan Seo, Kyungsun Han, Ojin Kwon, Dae-Jean Jo, Jun-Hwan Lee
Bee venom acupuncture (BVA) is an effective treatment for chronic low back pain (CLBP) through the pharmacological effects of bee venom and the simultaneous stimulation of acupoints. However, evidence of its efficacy and safety in humans remains unclear. Using a double-blind, randomized study, 54 patients with non-specific CLBP were assigned to the BVA and sham groups. All participants underwent six sessions of real or sham BVA for 3 weeks, in addition to administration of 180 mg of loxonin per day. The primary outcome, that is, "bothersomeness" derived from back pain, was assessed using the visual analog scale...
November 7, 2017: Toxins
https://www.readbyqxmd.com/read/29111171/hip-symptoms-physical-performance-and-health-status-in-older-adults-with-chronic-low-back-pain-a-preliminary-investigation
#7
Gregory E Hicks, J Megan Sions, Teonette O Velasco
OBJECTIVE: The purposes of this study were to determine: a) if there are differences in the prevalence of clinical hip symptoms between older adults with and without CLBP; and b) whether co-existing hip symptoms are associated with worse physical performance and poorer health-related quality of life (HRQOL). DESIGN: Case-control study SETTING: Individuals participated in a standardized evaluation in a clinical laboratory. PATIENT SAMPLE: Clinical hip symptoms, which are proposed predictors of radiographic hip osteoarthritis according to American College of Rheumatology guidelines, were evaluated in a volunteer sample of 54 community-dwelling older adults, aged 60-85, with CLBP and 54 age- and sex-matched healthy controls...
October 27, 2017: Archives of Physical Medicine and Rehabilitation
https://www.readbyqxmd.com/read/29103551/decision-support-tools-in-low-back-pain
#8
REVIEW
Veerle M H Coupé, Miranda L van Hooff, Marinus de Kleuver, Ewout W Steyerberg, Raymond W J G Ostelo
Information from individual classification systems or clinical prediction rules that aim to facilitate stratified care in low back pain is important but often not comprehensive enough to be used to support clinical decision-making. The development and implementation of a clinically useful decision support tool (DST) that considering all key features is a challenging enterprise, requiring a multidisciplinary approach. Key features are inclusion of all relevant treatment options, patient characteristics, and benefits and harms and presentation as an accessible and easy to use toolkit...
December 2016: Best Practice & Research. Clinical Rheumatology
https://www.readbyqxmd.com/read/29080466/improved-compensatory-postural-adjustments-of-the-deep-abdominals-following-exercise-in-people-with-chronic-low-back-pain
#9
Michael F Knox, Lucy S Chipchase, Siobhan M Schabrun, Paul W M Marshall
The purpose of this study was to determine if 8 weeks of exercise affects motor control in people with chronic low back pain (CLBP), measured by anticipatory (APAs) and compensatory postural adjustments (CPAs). APAs and CPAs were measured prior to and following 8 weeks in two groups of people with CLBP: an exercise group (n=12) who attended three exercise sessions per week for 8 weeks; and a non-exercise control group (n=12) who were advised to continue their usual activities for the duration of the study. APAs and CPAs were recorded during unilateral arm flexion, bilaterally from rectus abdominis (RA), transverse abdominis/internal oblique (TA/IO), and erector spinae (ES) via surface electromyography...
October 20, 2017: Journal of Electromyography and Kinesiology
https://www.readbyqxmd.com/read/29041942/patient-reported-health-related-quality-of-life-work-productivity-and-activity-impairment-during-treatment-with-alo-02-extended-release-oxycodone-and-sequestered-naltrexone-for-moderate-to-severe-chronic-low-back-pain
#10
Arnold J Weil, Elizabeth T Masters, Alexandra I Barsdorf, Almasa Bass, Glenn Pixton, Jacquelyn G Wilson, Gernot Wolfram
BACKGROUND: The efficacy of ALO-02, an abuse-deterrent formulation containing extended-release oxycodone and sequestered naltrexone, in the treatment of chronic low back pain (CLBP) was studied in a 12-week randomized controlled trial. Primary efficacy endpoint results have been published previously (Rauck et al., 2015). The current paper focuses on patient-reported outcomes for health-related quality of life (HRQL), work productivity, and activity impairment that were assessed during this study...
October 17, 2017: Health and Quality of Life Outcomes
https://www.readbyqxmd.com/read/29040298/relative-mobility-of-the-pelvis-and-spine-during-trunk-axial-rotation-in-chronic-low-back-pain-patients-a-case-control-study
#11
Masashi Taniguchi, Hiroshige Tateuchi, Satoko Ibuki, Noriaki Ichihashi
BACKGROUND: Trunk axial rotation is a risk factor for chronic low back pain (CLBP). The characteristics of rotational mobility in the pelvis and spine among CLBP patients are not fully understood. PURPOSE: The purpose of this study was to examine three-dimensional kinematic changes, and to compare the differences of rotational mobility and coupled motion, in patients with and without CLBP. METHODS: Fifteen patients with CLBP and 15 age and sex matched healthy subjects participated in this study...
2017: PloS One
https://www.readbyqxmd.com/read/29036904/biopsychosocial-measures-related-to-chronic-low-back-pain-postural-control-in-older-adults
#12
Ryan Hulla, Robert J Gatchel, Angela Liegey-Dougall
This study examined the biopsychosocial measures related to postural control in the growing population of older adults (i.e., 60 years and older). The sample of the study consisted of 129 older adults (M = 74.45, SD = 6.95), with 34 males and 95 females; 36 were classified with chronic low-back pain (CLBP), and 93 without chronic low-back pain (NCLBP). Physical and psychosocial constructs were analyzed as predictors for postural control measures. Additionally, gender and classification of low-back pain were examined as moderators for all physical and psychosocial measures...
October 14, 2017: Healthcare (Basel, Switzerland)
https://www.readbyqxmd.com/read/29035297/variability-in-strength-pain-and-disability-changes-in-response-to-an-isolated-lumbar-extension-resistance-training-intervention-in-participants-with-chronic-low-back-pain
#13
James Steele, James Fisher, Stewart Bruce-Low, Dave Smith, Neil Osborne, Dave Newell
Strengthening the lumbar extensor musculature is a common recommendation for chronic low back pain (CLBP). Although reported as effective, variability in response in CLBP populations is not well investigated. This study investigated variability in responsiveness to isolated lumbar extension (ILEX) resistance training in CLBP participants by retrospective analysis of three previous randomized controlled trials. Data from 77 participants were available for the intervention arms (males = 43, females = 34) 37 participants data (males = 20, females = 17) from the control arms...
October 16, 2017: Healthcare (Basel, Switzerland)
https://www.readbyqxmd.com/read/29035178/patient-perspectives-on-communication-with-primary-care-physicians-about-chronic-low-back-pain
#14
Sarah Evers, Clarissa Hsu, Karen J Sherman, Ben Balderson, Rene Hawkes, Georgie Brewer, Anne-Marie La Porte, John Yeoman, Dan Cherkin
OBJECTIVES: Chronic low back pain (CLBP) is a common health problem with challenges for providing satisfactory care. This study was undertaken to identify opportunities to improve key aspects of physicians' communications with CLBP-affected patients. METHODS: A series of 3 focus groups, each with 7 to 11 patients with CLBP, were recruited from primary care settings and grouped by risk level of reduced function resulting from back pain, to elicit perspectives about interactions with their primary care physicians...
2017: Permanente Journal
https://www.readbyqxmd.com/read/29025132/most-relevant-neuropathic-pain-treatment-and-chronic-low-back-pain-management-guidelines-a-change-pain-latin-america-advisory-panel-consensus
#15
Cesar Amescua-Garcia, Frantz Colimon, Carlos Guerrero, Aziza Jreige Iskandar, Maria Berenguel Cook, Patricia Bonilla, Durval Campos Kraychete, William Delgado Barrera, Jose Alberto Flores Cantisani, John Jairo Hernandez-Castro, Argelia Lara-Solares, Concepcion Perez Hernandez, Maria Antonieta Rico, Maria Del Rocio Guillen Nunez, Manuel Sempertegui Gallegos, Joao Batista Santos Garcia
Objective: Chronic pain conditions profoundly affect the daily living of a significant number of people and are a major economic and social burden, particularly in developing countries. The Change Pain Latin America (CPLA) advisory panel aimed to identify the most appropriate guidelines for the treatment of neuropathic pain (NP) and chronic low back pain (CLBP) for use across Latin America. Methods: Published systematic reviews or practice guidelines were identified by a systematic search of PubMed, the Guidelines Clearinghouse, and Google...
August 24, 2017: Pain Medicine: the Official Journal of the American Academy of Pain Medicine
https://www.readbyqxmd.com/read/29025059/mindfulness-for-chronic-low-back-pain-a-qualitative-analysis
#16
José G Luiggi-Hernandez, Jean Woo, Megan Hamm, Carol M Greco, Debra K Weiner, Natalia E Morone
Objective: Mindfulness is a nonpharmacologic mind-body therapy that has been shown to be effective in older adults with chronic low back pain (cLBP). There are few first-person accounts in the literature that describe the older adult experience and perspective while learning mindfulness and meditation to treat pain. The objective of this study was to investigate dominant themes present in the experiences of older adults applying mindfulness and meditation to cope with cLBP. Design: Qualitative analysis of four focus groups...
August 16, 2017: Pain Medicine: the Official Journal of the American Academy of Pain Medicine
https://www.readbyqxmd.com/read/28993113/the-cognitive-impact-of-chronic-low-back-pain-positive-effect-of-multidisciplinary-pain-therapy
#17
Marcus Schiltenwolf, Michael Akbar, Eva Neubauer, Simone Gantz, Herta Flor, Andreas Hug, Haili Wang
OBJECTIVES: Little is known about the affected cognitive problems in chronic low back pain patients. For this patient cohort research mostly focused on memory of pain, rather than cognitive difficulties related to pain. Chronic pain may be associated with specific (yet undefined) cognitive deficits that affect everyday behaviour. We set out to compare the cognitive function of patients with chronic low back pain (cLBP) in the course of multidisciplinary pain treatments before and after therapy...
October 6, 2017: Scandinavian Journal of Pain
https://www.readbyqxmd.com/read/28967357/in-the-spine-or-in-the-brain-recent-advances-in-pain-neuroscience-applied-in-the-intervention-for-low-back-pain
#18
REVIEW
Jo Nijs, Jacqui Clark, Anneleen Malfliet, Kelly Ickmans, Lennard Voogt, Sanneke Don, Hester den Bandt, Dorien Goubert, Jeroen Kregel, Iris Coppieters, Wim Dankaerts
Conservative, surgical and pharmacological strategies for chronic low back pain (CLBP) management offer at best modest effect sizes in reducing pain and related disability, indicating a need for improvement. Such improvement may be derived from applying contemporary pain neuroscience to the management of CLBP. Current interventions for people with CLBP are often based entirely on a "biomedical" or "psychological" model without consideration of information concerning underlying pain mechanisms and contemporary pain neuroscience...
September 2017: Clinical and Experimental Rheumatology
https://www.readbyqxmd.com/read/28949546/molecular-basis-of-gut-microbiome-associated-colorectal-cancer-a%C3%A2-synthetic-perspective
#19
Alan R Healy, Seth B Herzon
A significant challenge toward studies of the human microbiota involves establishing causal links between bacterial metabolites and human health and disease states. Certain strains of commensal Escherichia coli harbor the 54-kb clb gene cluster which codes for small molecules named precolibactins and colibactins. Several studies suggest colibactins are genotoxins and support a role for clb metabolites in colorectal cancer formation. Significant advances toward elucidating the structures and biosynthesis of the precolibactins and colibactins have been made using genetic approaches, but their full structures remain unknown...
October 12, 2017: Journal of the American Chemical Society
https://www.readbyqxmd.com/read/28946522/the-effect-of-manual-therapy-and-exercise-in-patients-with-chronic-low-back-pain-double-blind-randomized-controlled-trial
#20
Ozlem Ulger, Aynur Demirel, Müzeyyen Oz, Seval Tamer
BACKGROUND AND OBJECTIVES: To determine the effects of spinal stabilization exercises (SSE) and manual therapy methods on pain, function and quality of life (QoL) levels in individuals with chronic low back pain (CLBP). METHODS: A total of one-hundred thirteen patients diagnosed as CLBP were enrolled to the study. The patients allocated into Spinal Stabilization group (SG) and manual therapy group (MG), randomly. While SSE performed in SG, soft tissue mobilizations, muscle-energy techniques, joint mobilizations and manipulations were performed in MG...
June 12, 2017: Journal of Back and Musculoskeletal Rehabilitation
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