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Pediatric esophagic impedance

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https://www.readbyqxmd.com/read/28808763/characteristics-of-gastroesophageal-reflux-in-pediatric-patients-with-neurological-impairment
#1
Hisayoshi Kawahara, Yuko Tazuke, Hideki Soh, Noriaki Usui, Hiroomi Okuyama
PURPOSE: To clarify the characteristics of gastroesophageal reflux (GER) in pediatric patients with neurological impairment (NI). METHODS: Twenty-six patients with NI, 1-17-year-old, fed via a nasogastric tube were categorized based on the absence (group I) or presence (group II) of abnormal GER, defined with multichannel intraluminal impedance-pH monitoring as %time with an esophageal pH <4.0 being ≥5.0% or number of liquid/mixed bolus reflux events(RE) >70 in 24 h...
August 14, 2017: Pediatric Surgery International
https://www.readbyqxmd.com/read/28711175/the-prevalence-of-rome-iv-nonerosive-esophageal-phenotypes-in-children
#2
Lisa B Mahoney, Samuel Nurko, Rachel Rosen
OBJECTIVES: To assess the prevalence of Rome IV nonerosive esophageal phenotypes in children using multichannel intraluminal impedance testing and to describe the rates of proton pump inhibitor (PPI) responsiveness and the frequency of microscopic esophagitis in these patients. STUDY DESIGN: We conducted a retrospective review of all children ≥5 years of age who underwent esophagogastroduodenoscopy and multichannel intraluminal impedance testing off PPI therapy for evaluation of typical gastroesophageal reflux symptoms...
October 2017: Journal of Pediatrics
https://www.readbyqxmd.com/read/28604515/novel-pressure-impedance-parameters-for-evaluating-esophageal-function-in-pediatric-achalasia
#3
Maartje M J Singendonk, Taher I Omari, Nathalie Rommel, Michiel P van Wijk, Marc A Benninga, Rachel Rosen, Samuel Nurko
OBJECTIVE: In achalasia, absent peristalsis and reduced esophagogastric junction (EGJ) relaxation and compliance underlie dysphagia symptoms. Novel high-resolution impedance manometry (HRIM) variables, i.e. bolus presence time (BPT) and trans-EGJ-bolus flow time (BFT) have been developed to estimate the duration of EGJ opening and trans-EGJ bolus flow. The aim of this study was to evaluate esophageal motor function and bolus flow in children diagnosed with achalasia using these variables...
June 9, 2017: Journal of Pediatric Gastroenterology and Nutrition
https://www.readbyqxmd.com/read/28572979/complex-effects-of-high-flow-nasal-cannula-therapy-on-hemodynamics-in-the-pediatric-patient-after-cardiac-surgery
#4
EDITORIAL
Yu Inata, Muneyuki Takeuchi
BACKGROUND: The high-flow nasal cannula (HFNC) system has been widely used for children in various clinical settings. However, the physiological and clinical impact of HFNC therapy on the pediatric patient with respiratory distress after cardiac surgery has not been thoroughly investigated. MAIN BODY OF THE ABSTRACT: It seems logical to use HFNC as a primary therapy for post-extubation respiratory failure after congenital heart surgery, in which low cardiac output syndrome and upper airway obstruction are commonly encountered; the HFNC therapy alleviates the work of breathing and large negative swings of intrathoracic pressure, which in turn helps to decrease the systemic ventricular afterload...
2017: Journal of Intensive Care
https://www.readbyqxmd.com/read/28028956/assessment-of-clinical-symptoms-and-multichannel-intraluminal-impedance-and-ph-monitoring-in-children-after-thoracoscopic-repair-of-esophageal-atresia-and-distal-tracheoesophageal-fistula
#5
Barbara M Iwańczak, Agnieszka Kosmowska-Miśków, Anna Kofla-Dłubacz, Mateusz Palczewski, Michał Grabiński, Katarzyna Pawłowska, Krzysztof Matusiewicz, Dariusz Patkowski
BACKGROUND: Motility disturbances of the esophagus and gastroesophageal reflux disease (GERD) are observed frequently in children after repair of congenital esophageal atresia with distal tracheoesophageal fistula (EA/TEF). Recently, in many pediatric surgical centers, thoracoscopic repair was introduced, which theoretically would change the postoperative course. OBJECTIVES: The goal of the study was to assess physical development, disease symptoms, and GERD symptom frequency in children who underwent thoracoscopic surgery of congenital EA/TEF...
September 2016: Advances in Clinical and Experimental Medicine: Official Organ Wroclaw Medical University
https://www.readbyqxmd.com/read/28002887/pediatric-rumination-subtypes-a-study-using-high-resolution-esophageal-manometry-with-impedance
#6
R Rosen, L Rodriguez, S Nurko
BACKGROUND: The differential diagnosis of intractable reflux in children includes rumination syndrome, but confirming the diagnosis using antroduodenal manometry is invasive, is costly, and requires anesthesia. High-resolution esophageal manometry with impedance (HRM-MII) overcomes these limitations, and the goal of this study is to validate the use of HRM-MII as a diagnostic tool for rumination and to describe the subtypes of pediatric rumination. METHODS: We reviewed the HRM-MII tracings of 21 children presenting with symptoms of intractable reflux in whom rumination was being considered...
May 2017: Neurogastroenterology and Motility: the Official Journal of the European Gastrointestinal Motility Society
https://www.readbyqxmd.com/read/27920480/comparison-of-multichannel-intraluminal-impedance-ph-monitoring-and-reflux-scintigraphy-in-pediatric-patients-with-suspected-gastroesophageal-reflux
#7
COMPARATIVE STUDY
Nuray Uslu Kızılkan, Murat Fani Bozkurt, Inci Nur Saltık Temizel, Hülya Demir, Aysel Yüce, Biray Caner, Hasan Özen
AIM: To evaluate the agreement of multichannel intraluminal impedance-pH monitoring (MII-pHM) and gastroesophageal reflux scintigraphy (GES) for the diagnosis of gastroesophageal reflux disease. METHODS: Seventy-five consecutive patients with suspected gastroesophageal reflux disease (GERD) underwent 24-h combined MII-pHM recording and one hour radionuclide scintigraphy during the course of the MII-pHM study. Catheters with 6 impedance channels and 1 pH sensor were placed transnasally...
November 21, 2016: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/27736035/role-of-non-acid-gastro-esophageal-reflux-in-children-with-respiratory-symptoms
#8
Letizia Zenzeri, Paolo Quitadamo, Renato Tambucci, Dario Ummarino, Antonio Poziello, Erasmo Miele, Annamaria Staiano
OBJECTIVES: Respiratory symptoms are a possible atypical clinical picture of gastro-esophageal reflux disease (GERD). However, a significant number of patients with GERD-related respiratory symptoms do not report improvement despite aggressive acid-suppressive therapy. Some of these refractory cases may be due to the recently appreciated entity of non-acid or weakly acidic reflux. The aim of our study is to assess the pH-impedance features of GER inducing airway symptoms, compared with GER inducing typical gastro-intestinal (GI) symptoms...
May 2017: Pediatric Pulmonology
https://www.readbyqxmd.com/read/27604397/pepsin-in-saliva-as-a-biomarker-for-oropharyngeal-reflux-compared-with-24-hour-esophageal-impedance-ph-monitoring-in-pediatric-patients
#9
J E Fortunato, R B D'Agostino, M O Lively
BACKGROUND: Pepsin in saliva is a proposed biomarker for oropharyngeal reflux. Pepsin may be prevalent in saliva from subjects with gastro-esophageal reflux and may correlate with proximal reflux by intraluminal impedance/pH monitoring (MII/pH). METHODS: Patients (3 days to 17.6 years, n=90) undergoing 24-hour MII/pH monitoring and asymptomatic controls (2 months to 13.7 years, n=43) were included. Salivary pepsin was determined using a pepsin enzyme-linked immunosorbent assay...
February 2017: Neurogastroenterology and Motility: the Official Journal of the European Gastrointestinal Motility Society
https://www.readbyqxmd.com/read/27492870/pressure-flow-analysis-for-the-assessment-of-pediatric-oropharyngeal-dysphagia
#10
Lara Ferris, Nathalie Rommel, Sebastian Doeltgen, Ingrid Scholten, Stamatiki Kritas, Rammy Abu-Assi, Lisa McCall, Grace Seiboth, Katie Lowe, David Moore, Jenny Faulks, Taher Omari
OBJECTIVES: To determine which objective pressure-impedance measures of pharyngeal swallowing function correlated with clinically assessed severity of oropharyngeal dysphagia (OPD) symptoms. STUDY DESIGN: Forty-five children with OPD and 34 control children without OPD were recruited and up to 5 liquid bolus swallows were recorded with a solid-state high-resolution manometry with impedance catheter. Individual measures of pharyngeal and upper esophageal sphincter (UES) function and a swallow risk index composite score were derived for each swallow, and averaged data for patients with OPD were compared with those of control children without OPD...
October 2016: Journal of Pediatrics
https://www.readbyqxmd.com/read/27438415/combined-24-hours-esophageal-ph-monitoring-and-multichannel-intraluminal-impedance-for-comparison-of-gastroesophageal-reflux-in-children-with-typical-versus-atypical-symptoms-of-gastroesophageal-reflux-disease
#11
COMPARATIVE STUDY
Seyed Mohsen Dehghani, Seyed Alireza Taghavi, Hazhir Javaherizadeh, Maryam Nasri
BACKGROUND: - Gastroesophageal reflux disease is the most common esophageal disorder in pediatrics. OBJECTIVE: - The aim of this study was to compare reflux parameters of typical and atypical symptoms of gastroesophageal reflux disease using 24-hour esophageal pH monitoring and multichannel intraluminal impedance in pediatric population. METHODS: - In this prospective study, 43 patients aged less than 18 year with suspected gastroesophageal reflux disease were enrolled...
July 2016: Arquivos de Gastroenterologia
https://www.readbyqxmd.com/read/27369283/effects-and-efficacy-of-laparoscopic-fundoplication-in-children-with-gerd-a-prospective-multicenter-study
#12
MULTICENTER STUDY
Femke A Mauritz, J M Conchillo, L W E van Heurn, P D Siersema, C E J Sloots, R H J Houwen, D C van der Zee, M Y A van Herwaarden-Lindeboom
INTRODUCTION: Laparoscopic antireflux surgery (LARS) in children primarily aims to decrease reflux events and reduce reflux symptoms in children with therapy-resistant gastroesophageal reflux disease (GERD). The aim was to objectively assess the effect and efficacy of LARS in pediatric GERD patients and to identify parameters associated with failure of LARS. METHODS: Twenty-five children with GERD [12 males, median age 6 (2-18) years] were included prospectively...
March 2017: Surgical Endoscopy
https://www.readbyqxmd.com/read/27318379/esophageal-inlet-patch-an-under-recognized-cause-of-symptoms-in-children
#13
Giovanni Di Nardo, Cesare Cremon, Luca Bertelli, Salvatore Oliva, Roberto De Giorgio, Nico Pagano
OBJECTIVES: To determine the incidence of inlet patch (IP) and to assess the clinical and pathological features, role of the diagnostic workup in treatment decision making, efficacy of medical and endoscopic therapy, and natural history in a pediatric population. STUDY DESIGN: Consecutive patients aged <18 years (n = 1000) undergoing esophagogastroduodenoscopy were enrolled prospectively. Biopsy specimens were obtained from IPs and the proximal and distal esophagus, stomach, and duodenum...
September 2016: Journal of Pediatrics
https://www.readbyqxmd.com/read/27206156/supragastric-belching
#14
Joanne L S Ooi, Rukiye Vardar, Daniel Sifrim
PURPOSE OF REVIEW: Supragastric belching has recently gained recognition as a belching disorder of behavioral origin that can be accurately diagnosed on esophageal impedance monitoring. Its contribution to numerous other gastrointestinal disorders is beginning to be appreciated. Improved knowledge of its pathophysiology has enabled identification of therapeutic goals, some of which have been subject to formal study and demonstrated good outcomes. This review sets out to present and discuss new findings related to the improved understanding of the relationship between supragastric belching and other gastrointestinal disorders, as well as fresh concepts in terms of management...
July 2016: Current Opinion in Gastroenterology
https://www.readbyqxmd.com/read/27193974/laryngopharyngeal-reflux-in-children-with-chronic-otitis-media-with-effusion
#15
Anna Górecka-Tuteja, Izabela Jastrzębska, Jacek Składzień, Krzysztof Fyderek
BACKGROUND/AIMS: To evaluate the characteristic properties of laryngopharyngeal reflux (LPR) and gastroesophageal reflux (GER) in children with otitis media with effusion (OME) using 24-hour multichannel intraluminal impedance combined with dual-probe (pharyngeal and esophageal) pH-metry. METHODS: Children aged 7-10 years of age with OME underwent 24-hour multichannel intraluminal impedance pH-metry. The upper pH sensor was situated 1 cm above the upper esophageal sphincter, and the lower pH sensor was placed 3-5 cm above the lower esophageal sphincter...
July 30, 2016: Journal of Neurogastroenterology and Motility
https://www.readbyqxmd.com/read/26906020/laparoscopic-nissen-fundoplication-mainly-reduces-the-volume-of-acid-reflux-and-potentially-improves-mucosal-integrity-up-to-the-middle-esophagus-in-neurologically-impaired-children-detected-by-esophageal-combined-ph-multichannel-intraluminal-impedance-measurements
#16
Suguru Fukahori, Minoru Yagi, Shinji Ishii, Kimio Asagiri, Nobuyuki Saikusa, Naoki Hashizume, Motomu Yoshida, Daisuke Masui, Saki Sakamoto, Shihori Tsuruhisa, Tomohiro Kurahachi, Yoshiaki Tanaka
BACKGROUND: The aim of this study was to evaluate detailed changes of gastroesophageal reflux disease (GERD) in children before and after laparoscopic Nissen fundoplication (LNF) utilizing esophageal combined pH-multichannel intraluminal impedance (pH/MII) measurements. PATIENTS AND METHODS: Thirteen patients with neurological impairment, who received laparoscopic Nissen fundoplication (LNF) owing to refractory pathological GERD, were enrolled in this study. 24h pH/MII was conducted in all patients before and one year after LNF...
August 2016: Journal of Pediatric Surgery
https://www.readbyqxmd.com/read/26444666/congenital-esophageal-stenosis-diagnosed-in-an-infant-at-9-month-of-age
#17
F Savino, V Tarasco, S Viola, E Locatelli, M Sorrenti, A Barabino
Esophageal stenosis is a relatively uncommon condition in pediatrics and requires an accurate diagnostic approach. Here we report the case of a 9-month old female infant who presented intermittent vomiting, dysphagia and refusal of solid foods starting after weaning. She was treated for gastroesophageal reflux. At first, radiological investigation suggested achalasia, while esophagoscopy revelaed a severe congenital esophageal stenosis at the distal third of the esophagus. She underwent four endoscopic balloon dilatations that then allowed her to swallow solid food with intermittent mild dysphagia...
2015: Italian Journal of Pediatrics
https://www.readbyqxmd.com/read/26439568/pp-3-the-utility-of-integrated-relaxation-pressure-to-predict-achalasia-in-children
#18
T Ciecierega, C V Crawford, R Zarnegar, N A Tipnis
BACKGROUND: Esophageal High Resolution Manometry (eHRM) is a widely available technique to evaluate dysphagia symptoms in children. In adults, the 4 second integrated relaxation pressure (IRP4 s) has been used to characterize lower esophageal sphincter function and esophageal obstruction. To date, no study has evaluated the utility of the IRP to predict achalasia in children. AIMS: To determine the utility of the IRP4 s to predict achalasia in a cohort of children with achalasia...
October 2015: Journal of Pediatric Gastroenterology and Nutrition
https://www.readbyqxmd.com/read/26437981/impaired-esophageal-motor-function-in-eosinophilic-esophagitis
#19
REVIEW
Cecilio Santander, Carlos M Chavarría-Herbozo, Irene Becerro-González, Diego Burgos-Santamaría
Eosinophilic esophagitis is a chronic immunoallergic inflammatory disease of the esophagus that represents a major cause of digestive morbidity among the pediatric and young adult populations. Despite the fact that key symptoms in adults include dysphagia and food impaction, many patients lack structural changes in the esophagus to account for their complaints, which suggests the presence of underlying motor disorders and esophageal distensibility impairment. In the last few years the esophageal motility of these patients has been studied using various approaches, most particularly high-resolution manometry, ambulatory manometry, and impedance planimetry...
October 2015: Revista Española de Enfermedades Digestivas
https://www.readbyqxmd.com/read/26309245/dysphagia-in-children-with-esophageal-atresia-current-diagnostic-options
#20
REVIEW
Maissa Rayyan, Karel Allegaert, Taher Omari, Nathalie Rommel
Dysphagia or swallowing disorder is very common (range, 15-52%) in patients with esophageal atresia. Children present with a wide range of symptoms. The most common diagnostic tools to evaluate esophageal dysphagia, such as upper barium study and manometry, aim to characterize anatomy and function of the esophageal body and the esophagogastric junction (EGJ). Using these technologies, a variety of pathological motor patterns have been identified in children with esophageal atresia. However, the most challenging part of diagnosing patients with esophageal dysphagia lies in the fact that these methods fail to link functional symptoms such as dysphagia with the esophageal motor disorders observed...
August 2015: European Journal of Pediatric Surgery
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