keyword
https://read.qxmd.com/read/24976698/breath-tests-and-irritable-bowel-syndrome
#21
REVIEW
Satya Vati Rana, Aastha Malik
Breath tests are non-invasive tests and can detect H₂ and CH₄ gases which are produced by bacterial fermentation of unabsorbed intestinal carbohydrate and are excreted in the breath. These tests are used in the diagnosis of carbohydrate malabsorption, small intestinal bacterial overgrowth, and for measuring the orocecal transit time. Malabsorption of carbohydrates is a key trigger of irritable bowel syndrome (IBS)-type symptoms such as diarrhea and/or constipation, bloating, excess flatulence, headaches and lack of energy...
June 28, 2014: World Journal of Gastroenterology: WJG
https://read.qxmd.com/read/24443064/fructose-trehalose-and-sorbitol-malabsorption
#22
REVIEW
M Montalto, A Gallo, V Ojetti, A Gasbarrini
Carbohydrate malabsorption is a frequent clinical condition, often associated with abdominal symptoms. Although lactose represents the most commonly malabsorbed sugar, also other carbohydrates, such as fructose, trehalose and sorbitol may be incorrectly absorbed in the small intestine. Fructose malabsorption seems more common in patients with functional bowel disease, even if randomized and controlled studies on these topic were few and on small samples. Interpretation of breath hydrogen testing is difficult...
2013: European Review for Medical and Pharmacological Sciences
https://read.qxmd.com/read/24300825/the-malabsorption-of-commonly-occurring-mono-and-disaccharides-levels-of-investigation-and-differential-diagnoses
#23
REVIEW
Martin Raithel, Michael Weidenhiller, Alexander Fritz-Karl Hagel, Urban Hetterich, Markus Friedrich Neurath, Peter Christopher Konturek
BACKGROUND: Adverse food reactions (AFR) have has recently attracted increased attention from the media and are now more commonly reported by patients. Its classification, diagnostic evaluation, and treatment are complex and present a considerable challenge in clinical practice. Non-immune-mediated types of food intolerance have a cumulative prevalence of 30% to 40%, while true (immune-mediated) food allergies affect only 2% to 5% of the German population. METHOD: We selectively searched the literature for pertinent publications on carbohydrate malabsorption, with special attention to published guidelines and position papers...
November 15, 2013: Deutsches Ärzteblatt International
https://read.qxmd.com/read/21429446/the-clinical-impact-of-carbohydrate-malabsorption
#24
REVIEW
Peter Born
Malabsorption of carbohydrates such as fructose, lactose or sorbitol can often be detected among patients suffering from so-called non specific abdominal complaints. Sometimes the differential diagnosis may be difficult. So far successful treatment consists of dietary interventions only. Nevertheless, many questions are remaining still unanswered.
March 2011: Arab Journal of Gastroenterology: the Official Publication of the Pan-Arab Association of Gastroenterology
https://read.qxmd.com/read/20369147/ibs-or-intolerance
#25
JOURNAL ARTICLE
Terry Bolin
BACKGROUND: The contribution of specific foods to the genesis of symptoms in irritable bowel syndrome (IBS) has been increasingly recognised in recent years. OBJECTIVE: This article discusses the dietary triggers for IBS and the role of diagnostic testing in patients with IBS. DISCUSSION: In addition to the long standing implication of lactose in lactase deficient patients, fermentable dietary oligosaccharides, disaccharides, monosaccharides and polyols, together with very low carbohydrate diets, have been increasingly recognised as important in the causation and treatment of irritable bowel syndrome...
December 2009: Australian Family Physician
https://read.qxmd.com/read/19765364/fructose-sorbitol-malabsorption
#26
REVIEW
Fernando Fernández-Bañares, Maria Esteve, Josep M Viver
Important dietary carbohydrates such as fructose and sorbitol are incompletely absorbed in the normal small intestine. This malabsorption is sometimes associated with abdominal complaints and diarrhea development, symptoms indistinguishable from those of functional bowel disease. Recently, polymerized forms of fructose (fructans) also were implicated in symptom production in patients with irritable bowel syndrome (IBS). Evidence from uncontrolled and controlled challenge studies suggests that malabsorbed sugars (fructose, sorbitol, lactose) and fructans may act as dietary triggers for clinical symptoms suggestive of IBS...
October 2009: Current Gastroenterology Reports
https://read.qxmd.com/read/19559137/the-role-of-diet-in-symptoms-of-irritable-bowel-syndrome-in-adults-a-narrative-review
#27
REVIEW
William D Heizer, Susannah Southern, Susan McGovern
This review summarizes what is known about the effect of diet on irritable bowel syndrome (IBS) symptoms emphasizing data from randomized, controlled clinical trials. Studies suggest that IBS symptoms in one quarter of patients may be caused or exacerbated by one or more dietary components. Recent studies indicate that a diet restricted in fermentable, poorly absorbed carbohydrates, including fructose, fructans (present in wheat and onions), sorbitol, and other sugar alcohols is beneficial, but confirmatory studies are needed...
July 2009: Journal of the American Dietetic Association
https://read.qxmd.com/read/19505663/methods-and-functions-breath-tests
#28
REVIEW
Barbara Braden
Breath tests provide a valuable non-invasive diagnostic strategy to in vivo assess a variety of enzyme activities, organ functions or transport processes. Both the hydrogen breath tests and the (13)C-breath tests using the stable isotope (13)C as tracer are non-radioactive and safe, also in children and pregnancy. Hydrogen breath tests are widely used in clinical practice to explore gastrointestinal disorders. They are applied for diagnosing carbohydrate malassimilation, small intestinal bacterial overgrowth and for measuring the orocecal transit time...
2009: Best Practice & Research. Clinical Gastroenterology
https://read.qxmd.com/read/19452588/adult-hereditary-fructose-intolerance
#29
JOURNAL ARTICLE
Mohamed Ismail Yasawy, Ulrich Richard Folsch, Wolfgang Eckhard Schmidt, Michael Schwend
Hereditary fructose intolerance (HFI) is an under-recognized, preventable life-threatening condition. It is an autosomal recessive disorder with subnormal activity of aldolase B in the liver, kidney and small bowel. Symptoms are present only after the ingestion of fructose, which leads to brisk hypoglycemia, and an individual with continued ingestion will exhibit vomiting, abdominal pain, failure to thrive, and renal and liver failure. A diagnosis of HFI was made in a 50-year-old woman on the basis of medical history, response to IV fructose intolerance test, demonstration of aldolase B activity reduction in duodenal biopsy, and molecular analysis of leukocyte DNA by PCR showed homozygosity for two doses of mutant gene...
May 21, 2009: World Journal of Gastroenterology: WJG
https://read.qxmd.com/read/18609141/plasma-glucagon-like-peptide-1-and-peptide-yy-levels-are-not-altered-in-symptomatic-fructose-sorbitol-malabsorption
#30
COMPARATIVE STUDY
Jørgen Valeur, Eliann Øines, Mette Helvik Morken, Jens Juul Holst, Arnold Berstad
OBJECTIVE: Carbohydrate malabsorption causes more symptoms in patients with functional gastrointestinal disorders than in healthy individuals. The purpose of this study was to investigate whether this could be explained by differences in ileal brake hormone secretion. MATERIAL AND METHODS: Eighteen consecutive patients with functional abdominal complaints, referred to our clinic for investigation of self-reported food hypersensitivity, were included in the study and compared with 15 healthy volunteers...
2008: Scandinavian Journal of Gastroenterology
https://read.qxmd.com/read/17086866/carbohydrate-malabsorption-in-clinical-routine-a-prospective-observational-study
#31
JOURNAL ARTICLE
Peter Born, Marina Sekatcheva, Thomas Rösch, Meinhard Classen
BACKGROUND/AIMS: Nonspecific abdominal symptoms are a serious problem throughout the world. Among the multitude of differential diagnoses in carbohydrate malabsorption, only incomplete absorption of lactose is mentioned, while malabsorption of fructose and sorbitol--which occurs much more often, at least in the Western world--is usually not included. METHODOLOGY: During a 6-month period, all patients (n=90; 33 males, median age 45 years, range 10-81; 57 females, median age 47 years, range 15-71) who consecutively presented for H2 exhalation tests were evaluated...
September 2006: Hepato-gastroenterology
https://read.qxmd.com/read/16573414/hepatic-and-renal-failure-associated-with-amiodarone-infusion-in-a-patient-with-hereditary-fructose-intolerance
#32
JOURNAL ARTICLE
B J Curran, J H Havill
Hereditary fructose intolerance is a rare inherited metabolic disorder. Although fructose intolerance usually presents in the paediatric age group, individuals can survive into adulthood by self.manipulation of diet. Hospitalisation can become a high.risk environment for these individuals because of loss of control of their strict dietary constraints and the added danger of administration of medications containing fructose, sucrose and sorbitol. We report a case of hereditary fructose intolerance in an adult presenting with hepatic and renal failure associated with an amiodarone infusion and explore the possibility of polysorbate 80 as a cause of this patient's hepatic and renal failure...
June 2002: Critical Care and Resuscitation: Journal of the Australasian Academy of Critical Care Medicine
https://read.qxmd.com/read/16410032/sugar-malabsorption-in-functional-abdominal-bloating-a-pilot-study-on-the-long-term-effect-of-dietary-treatment
#33
JOURNAL ARTICLE
Fernando Fernández-Bañares, Mercé Rosinach, Maria Esteve, Montserrat Forné, Jorge C Espinós, Josep Maria Viver
BACKGROUND: Functional abdominal bloating is a functional bowel disorder dominated by a feeling of abdominal fullness without sufficient criteria for another functional gastrointestinal disorder. Gas-related complaints (i.e., passage of flatus), which are present in a subgroup of these patients, might be associated with carbohydrate malabsorption. AIM: To evaluate the presence of lactose and/or fructose plus sorbitol malabsorption, and the long-term efficacy of malabsorbed sugar-free diets, in patients with Rome II criteria of functional abdominal bloating and gas-related symptoms...
October 2006: Clinical Nutrition
https://read.qxmd.com/read/16142616/-clinically-relevant-breath-tests-in-gastroenterological-diagnostics-recommendations-of-the-german-society-for-neurogastroenterology-and-motility-as-well-as-the-german-society-for-digestive-and-metabolic-diseases
#34
REVIEW
J Keller, A Franke, M Storr, F Wiedbrauck, J Schirra
H (2)- and (13)C-breath tests are valuable non-invasive diagnostic tools for gastroenterological diseases. H (2)-breath tests are clinically established for the diagnosis of carbohydrate intolerance resulting from malabsorption (H (2)-breath tests with lactose, fructose, saccharose, sorbitol), of bacterial overgrowth (glucose H (2)-breath test) and for measurement of orcoceal transit time (lactulose H (2)-breath test). The (13)C-urea breath test is regarded as the "gold standard" procedure for the diagnosis of Helicobacter pylori infection...
September 2005: Zeitschrift Für Gastroenterologie
https://read.qxmd.com/read/11258556/coincidental-malabsorption-of-lactose-fructose-and-sorbitol-ingested-at-low-doses-is-not-common-in-normal-adults
#35
JOURNAL ARTICLE
S D Ladas, I Grammenos, P S Tassios, S A Raptis
Normal subjects may incompletely absorb either lactose, fructose, or sorbitol and may therefore have abdominal symptoms. The frequency of coincidental malabsorption of these sugars is not known. This is clinically important, since we often ingest them during the same day and malabsorption may cause abdominal symptoms. To shed light on this issue we studied 32 normal subjects. Volunteers drank in random order the following solutions: 20 g lactulose, 50 g sucrose, 50 and 25 g lactose, 50 and 25 g fructose, 20 and 10 g sorbitol...
December 2000: Digestive Diseases and Sciences
https://read.qxmd.com/read/11099057/fructose-and-sorbitol-reduced-diet-improves-mood-and-gastrointestinal-disturbances-in-fructose-malabsorbers
#36
JOURNAL ARTICLE
M Ledochowski, B Widner, H Bair, T Probst, D Fuchs
BACKGROUND: Fructose malabsorption is characterized by the inability to absorb fructose efficiently. As a consequence fructose reaches the colon where it is broken down by bacteria to short fatty acids, CO2 and H2. Bloating, cramps, osmotic diarrhea and other symptoms of irritable bowel syndrome are the consequences and can be seen in about 50% of fructose malabsorbers. We have previously shown that fructose malabsorption is associated with early signs of mental depression and low serum tryptophan concentrations...
October 2000: Scandinavian Journal of Gastroenterology
https://read.qxmd.com/read/10979349/carbohydrate-malabsorption-and-the-effect-of-dietary-restriction-on-symptoms-of-irritable-bowel-syndrome-and-functional-bowel-complaints
#37
JOURNAL ARTICLE
R Goldstein, D Braverman, H Stankiewicz
BACKGROUND: Carbohydrate malabsorption of lactose, fructose and sorbitol has already been described in normal volunteers and in patients with functional bowel complaints including irritable bowel syndrome. Elimination of the offending sugar(s) should result in clinical improvement. OBJECTIVE: To examine the importance of carbohydrate malabsorption in outpatients previously diagnosed as having functional bowel disorders, and to estimate the degree of clinical improvement following dietary restriction of the malabsorbed sugar(s)...
August 2000: Israel Medical Association Journal: IMAJ
https://read.qxmd.com/read/9610797/hereditary-fructose-intolerance
#38
REVIEW
M Ali, P Rellos, T M Cox
Hereditary fructose intolerance (HFI, OMIM 22960), caused by catalytic deficiency of aldolase B (fructose-1,6-bisphosphate aldolase, EC 4.1.2.13), is a recessively inherited condition in which affected homozygotes develop hypoglycaemic and severe abdominal symptoms after taking foods containing fructose and cognate sugars. Continued ingestion of noxious sugars leads to hepatic and renal injury and growth retardation; parenteral administration of fructose or sorbitol may be fatal. Direct detection of a few mutations in the human aldolase B gene on chromosome 9q facilitates the genetic diagnosis of HFI in many symptomatic patients...
May 1998: Journal of Medical Genetics
https://read.qxmd.com/read/9440643/fructose-and-sorbitol-malabsorption-in-ambulatory-patients-with-functional-dyspepsia-comparison-with-lactose-maldigestion-malabsorption
#39
COMPARATIVE STUDY
D Mishkin, L Sablauskas, M Yalovsky, S Mishkin
The aim of this study was to study sugar maldigestion/malabsorption in patients with functional dyspepsia using H2 breath testing. End-expiratory breath H2 after separate challenges with lactose (25 g), fructose (25 g), and sorbitol (5 g) were used to determine malabsorption, as well as small bowel transit time (SBTT). Five hundred twenty patients with functional dyspepsia received all three challenges. Smaller groups were also tested after lactulose (10 g, N = 36) and glucose (50 g, N = 90) challenges. Fructose and sorbitol were closely linked with respect to absorption and malabsorption status...
December 1997: Digestive Diseases and Sciences
https://read.qxmd.com/read/8704013/-carbohydrates-no-glucose-in-parenteral-nutrition-a-fading-concept
#40
JOURNAL ARTICLE
A García de Lorenzo, J M Culebras, A Zarazaga, J A Rodríguez Montes
An update is made on the binominal use/benefit of non-glucose carbohydrates (polyalcohols or polyols) in parenteral nutrition. The most recently published results, despite the controversy from different areas, have motivated the updating of the criteria metabolic aspects, indications and contraindications of the different carbohydrates alternatives of glucose (xylitol, sorbitol, glycerol, fructose), in the parenteral nutrition of patients with different degrees of aggression and situations of glucose intolerance or insulin resistance...
January 1996: Nutrición Hospitalaria: Organo Oficial de la Sociedad Española de Nutrición Parenteral y Enteral
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