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https://www.readbyqxmd.com/read/28718615/development-of-nanofiber-sponges-containing-nerve-guidance-conduit-for-peripheral-nerve-regeneration-in-vivo
#1
Binbin Sun, Zi-Fei Zhou, Tong Wu, Weiming Chen, Dawei Li, Hao Zheng, Hany El-Hamshary, Salem S Al-Deyab, Xiumei Mo, Yinxian Yu
In the study of hollow nerve guidance conduit (NGC), the dispersion of regenerated axons always confused the researchers. To address this problem, filler-containing NGC was prepared, which showed better effect in the application of nerve tissue engineering. In this study, nanofiber sponges with abundant macro-pores, high porosity, and superior compressive strength were fabricated by electrospinning and freeze-drying. Poly (l-lactic acid-co-ε-caprolactone)/silk fibroin (PLCL/SF) nanofiber sponges were used as filler to prepare three-dimensional nanofiber sponges-containing (NS-containing) NGC...
July 18, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28718333/anomalous-radial-artery-as-an-incidental-finding-during-a-routine-carpal-tunnel-release
#2
Charles A Gober, Tarik Mujadzic, John E Hershman, Mirsad M Mujadzic
BACKGROUND: Compression of the median nerve at the wrist, or carpal tunnel syndrome, is the most commonly recognized nerve entrapment syndrome. Carpal tunnel syndrome is usually caused by compression of the median nerve due to synovial swelling, tumor, or anomalous anatomical structure within the carpal tunnel. METHODS: During a routine carpal tunnel decompression, a large vessel was identified within the carpal tunnel. RESULTS: The large vessel was the radial artery...
February 1, 2017: Hand: Official Journal of the American Association for Hand Surgery
https://www.readbyqxmd.com/read/28718264/malignant-infantile-osteopetrosis
#3
Saima Gillani, Zaheer Abbas
Two main forms of osteopetrosis are recognized, a severe autosomal recessive form (MIM 259700) with an incidence of approximately 1 in 250,000 births and a mild autosomal dominant form (MIM166600) with an incidence of 1 in 20,000 births. Intrinsic disturbances of osteoclastic function due to mutations in genes encoding osteoclast-specific subunits of the vacuolar proton pump (TCIRG1, CLCN7) are found in most patients with recessive form. Mutations of CLCN7 are observed in dominant form of osteopetrosis .The recessive form of ostreopetrosis, i...
April 2017: Journal of Ayub Medical College, Abbottabad: JAMC
https://www.readbyqxmd.com/read/28717296/surgical-management-of-laterognathia-in-orthofacial-surgery
#4
J M García Y Sánchez, C L Gómez Rodríguez, J Romero Flores
INTRODUCTION: Each year around the world, various surgical procedures are carried out with the goal of correcting laterognathia; both the intraoral vertical ramus osteotomy (IVRO) and bilateral sagittal split ramus osteotomy (OSB) have been the most used techniques in mandibular surgery. These techniques have advantages and disadvantages; for example the advantages of the OSB include: increased coefficient of friction between bony segments, for both the forward and the retroposition, as well as decrease in the time of intermaxillary fixation (IMF)...
September 2017: Journal of Maxillofacial and Oral Surgery
https://www.readbyqxmd.com/read/28717053/pure-autonomic-failure
#5
REVIEW
Thomas P Brown
Pure autonomic failure is a degenerative disorder of the peripheral autonomic nervous system. Patients experience symptomatic hypotension that requires them to sit, squat or lie down to prevent syncope. It is associated with characteristic histopathological findings, resulting in neuronal cytoplasmic inclusions in the peripheral autonomic nerves. These lesions are responsible for defects in the synthesis and release of norepinephrine from sympathetic nerve terminals, resulting in significant hypotension. Patients with autonomic failure also have exaggerated blood pressure responses to common stimuli such as food or fluid intake, heat, exercise and medications...
July 17, 2017: Practical Neurology
https://www.readbyqxmd.com/read/28716694/-isolated-long-thoracic-nerve-palsy-more-than-meets-the-eye
#6
Andrés A Maldonado, Scott L Zuckerman, B Matthew Howe, Michelle L Mauermann, Robert J Spinner
INTRODUCTION: Two main hypotheses have been proposed for the pathophysiology of long thoracic nerve (LTN) palsy: nerve compression and nerve inflammation. We hypothesized that critical reinterpretation of electrodiagnostic (EDX) studies and MRIs of patients with a diagnosis of non-traumatic isolated LTN palsy could provide insight into the pathophysiology and, potentially, the treatment. MATERIAL AND METHODS: A retrospective review was performed of all patients with a diagnosis of non-traumatic isolated LTN palsy and an EDX and brachial plexus or shoulder MRI studies performed at our institution...
June 27, 2017: Journal of Plastic, Reconstructive & Aesthetic Surgery: JPRAS
https://www.readbyqxmd.com/read/28713629/abducent-nerve-palsy-after-microballoon-compression-of-the-trigeminal-ganglion-case-report
#7
Cassiano Marchi, Paulo Henrique Pires de Aguiar, Ana Maria Moura, Giovanna Matricardi, Carolina Utsunomya Muniz, Rogério Aires, Flávia Gehrke, Natally Santiago, Samuel Simis
BACKGROUND: Trigeminal neuralgia (TN) is the most common type of facial neuralgia with incidence of 26.8/100,000 person year. In general, this scenario is characterized by a lancinating, unilateral, paroxysmal pain in the area of the fifth cranial nerve. Several treatment methods, including the injection of ethyl alcohol or butyl alcohol into the ganglion, the glycerol injection into the trigeminal cistern, peripheral nerve divisions, the radiofrequency thermocoagulation of the preganglionic fibers, and radiosurgery has been used for TN...
2017: Surgical Neurology International
https://www.readbyqxmd.com/read/28712884/the-supraorbital-region-revisited-an-anatomic-exploration-of-the-neuro-vascular-bundle-with-regard-to-frontal-migraine-headache
#8
Valeria Berchtold, Hannes Stofferin, Bernhard Moriggl, Erich Brenner, Reinhard Pauzenberger, Marko Konschake
BACKGROUND: Recent findings on the pathogenesis of frontal migraine headache support, besides a central vasogenic cause, an alternative peripheral mechanism involving compressed craniofacial nerves. This is further supported by the efficiency of botulinum toxin injections as a new treatment option in frontal migraine headache patients. METHODS: The supraorbital regions of 22 alcohol-glycerine-embalmed facial halves of both sexes were dissected. Both the supratrochlear and supraorbital nerves (STN and SON, respectively) were identified, and their relationship with the corrugator supercilii muscle (CSM) was investigated by dissection and ultrasound...
June 27, 2017: Journal of Plastic, Reconstructive & Aesthetic Surgery: JPRAS
https://www.readbyqxmd.com/read/28710985/spinal-cord-compression-secondary-to-idiopathic-thoracic-epidural-lipomatosis-in-an-adolescent-a-case-report-and-review-of-literature
#9
Rumaiza Al-Yafeai, Yazid Maghrabi, Hussein Malibary, Saleh Baeesa
INTRODUCTION: Spinal epidural lipomatosis (SEL) is a rare condition that presents with progressive spinal cord or nerve root compression. It is commonly reported in patients receiving long-term exogenous steroid therapy or in patients with endogenous steroid overproduction. The occurrence of this condition as an idiopathic entity is rarely reported. CASE PRESENTATION: The authors present the clinical course and outcome of a 16-year-old male student, who presented with progressive spastic paraparesis of a one-year duration caused by idiopathic spinal epidural lipomatosis...
July 6, 2017: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/28706767/surgical-excision-of-a-symptomatic-thoracic-nerve-root-perineural-cyst-resulting-in-complete-resolution-of-symptoms-a-case-report
#10
Zaid Aljuboori, Alae Yaseen, Jessica Simpson, Maxwell Boakye
Tarlov (perineural) cysts of the nerve root are common and usually incidental findings during magnetic resonance imaging (MRI) of the lumbosacral spine. There are a few case reports where symptomatic thoracic perineural cysts have been described in the literature. We report a case of a high thoracic nerve root perineural cyst that failed conservative therapy, requiring surgical intervention. Our patient presented with radicular symptoms involving the left hand. Imaging workup revealed a cystic lesion of the left T1 nerve root at the level of the foramen...
June 12, 2017: Curēus
https://www.readbyqxmd.com/read/28705700/incidental-primary-intradural-carcinoid-tumor-in-a-patient-with-lumbar-radiculopathy
#11
Stavros Koustais, Philip O'Halloran, Alfrazdaq Hassan, Francesca Brett, Steven Young
BACKGROUND: Carcinoid tumors are neuroendocrine neoplasms derived from enterochromaffin cells. Central nervous system involvement is rare. The reported cases include metastases to brain or spinal cord, as well as primary skeletal or extradural disease resulting in compressive myelo-radiculopathy. There are two previously reported cases of primary intradural extramedullary carcinoid tumor, presenting with compressive symptoms. We report the first case of primary incidental intradural extramedullary carcinoid tumor...
July 10, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28702393/the-arcade-of-struthers-an-anatomical-study-and-clinical-implications
#12
Edie Benedito Caetano, João José Sabongi Neto, Luiz Angelo Vieira, Maurício Ferreira Caetano
OBJECTIVE: To determine the frequency and features of the arcade of Struthers, and to assess its clinical implication in ulnar nerve compression. METHOD: Forty arms from 26 cadaver specimens were dissected in the Anatomy Laboratory of this institution. The extension of the arcade, distance from the medial epicondyle, and relation with ulnar nerve were recorded. RESULTS: The arcade of Struthers was identified in 40 dissected arms (100%). In 29 (72...
May 2017: Revista Brasileira de Ortopedia
https://www.readbyqxmd.com/read/28699131/-pancreas-compressionless-gastrectomy-a-novel-laparoscopic-approach-for-suprapancreatic-lymph-node-dissection
#13
Masahiro Tsujiura, Naoki Hiki, Manabu Ohashi, Souya Nunobe, Koshi Kumagai, Satoshi Ida, Yasuhiro Okumura, Takeshi Sano, Toshiharu Yamaguchi
BACKGROUND: In radical operations for gastric cancer, a balance between the quality of lymph node dissection and safety of surgery must be ensured. During suprapancreatic lymphadenectomy in laparoscopic gastrectomy (LG), an adequate operative field should be safely and effectively established to reduce pancreas-related complications. We present a novel approach that avoids direct compression of the pancreas in LG and describe the surgical outcomes of this method. METHODS: We historically compressed the pancreas during suprapancreatic lymph node dissection in LG to obtain an adequate operative field but have since modified our operative technique...
July 11, 2017: Annals of Surgical Oncology
https://www.readbyqxmd.com/read/28695207/peripheral-myelin-protein-22-alters-membrane-architecture
#14
Kathleen F Mittendorf, Justin T Marinko, Cheri M Hampton, Zunlong Ke, Arina Hadziselimovic, Jonathan P Schlebach, Cheryl L Law, Jun Li, Elizabeth R Wright, Charles R Sanders, Melanie D Ohi
Peripheral myelin protein 22 (PMP22) is highly expressed in myelinating Schwann cells of the peripheral nervous system. PMP22 genetic alterations cause the most common forms of Charcot-Marie-Tooth disease (CMTD), which is characterized by severe dysmyelination in the peripheral nerves. However, the functions of PMP22 in Schwann cell membranes remain unclear. We demonstrate that reconstitution of purified PMP22 into lipid vesicles results in the formation of compressed and cylindrically wrapped protein-lipid vesicles that share common organizational traits with compact myelin of peripheral nerves in vivo...
July 2017: Science Advances
https://www.readbyqxmd.com/read/28694634/junctional-chiasmatic-syndrome-due-to-large-anterior-communicating-artery-aneurysm
#15
Maruthi Kesani, Pavan Kumar Pelluru, Suchanda Bhattacharjee, Rajesh Alugolu, A K Purohit
Even though aneurysm involving the anterior communicating artery (A Com A) was common in clinical practice, producing compressive symptoms such as visual loss was rare. We report a case, in which patient had gradually progressive visual loss with features of the junctional chiasmatic syndrome, imaging revealed partially thrombosed large A Com A aneurysm. Intraoperatively, aneurysm was found compressing the optic chiasm and right optic nerve, following clipping and decompression of the optic nerve and chiasm there was gradually improvement in the vision over 2 weeks postoperatively...
July 2017: Journal of Neurosciences in Rural Practice
https://www.readbyqxmd.com/read/28691025/protective-and-predisposing-morphological-factors-in-suprascapular-nerve-entrapment-syndrome-a-fundamental-review-based-on-recent-observations
#16
REVIEW
Piotr Łabętowicz, Marek Synder, Mariusz Wojciechowski, Krzysztof Orczyk, Hubert Jezierski, Mirosław Topol, Michał Polguj
Suprascapular nerve entrapment syndrome (SNES) is a neuropathy caused by compression of the nerve along its course. The most common compression sites include the suprascapular notch and the spinoglenoid notch. The aim of this article was to review the anatomical factors influencing the occurrence of SNES in the light of the newest reports. Potential predisposing morphological factors include a V-shaped, narrow, or "deep" suprascapular notch; a band-shaped, bifurcated, or completely ossified superior transverse scapular ligament (STSL); particular arrangements of the suprascapular nerve and vessels at the suprascapular notch...
2017: BioMed Research International
https://www.readbyqxmd.com/read/28689655/robotic-resection-of-a-symptomatic-parasitic-leiomyoma-from%C3%A2-the%C3%A2-obturator-fossa
#17
Gulden Menderes, Belinda Nhundu, Karen Levy, Dan-Arin Silasi
STUDY OBJECTIVE: To demonstrate a technique for robotically resecting a parasitic leiomyoma from the obturator fossa. DESIGN: Case report and a step-by-step video demonstration of resection of a symptomatic parasitic leiomyoma (Canadian Task Force classification III). SETTING: Tertiary referral center in New Haven, Connecticut. INTERVENTIONS: This 48-year-old Caucasian female had undergone a previous total abdominal hysterectomy for uterine leiomyomas...
July 7, 2017: Journal of Minimally Invasive Gynecology
https://www.readbyqxmd.com/read/28689485/therapeutic-ultrasound-after-sciatic-nerve-compression-of-wistar-rats
#18
Gladson Ricardo Flor Bertolini, Jhenifer Karvat, Camila Mayumi Martin Kakihata, Lucinéia de Fátima Chasko Ribeiro, Rose Meire Costa Brancalhão
OBJECTIVES: The present study analyzed the effect of therapy with therapeutic ultrasound on the sciatic nerve after compression injury, comparing two similar doses of SATA. METHODS: In total, 32 Wistar rats were used, divided into the following groups: CG - control; IG - compression injury of the sciatic nerve; IGCU - injury and continuous ultrasound; and IGPU - injury and 20% pulsed ultrasound. The treatment with ultrasound started on the 3rd postoperative day, with a frequency of 1 MHz, 0...
July 8, 2017: Neurological Research
https://www.readbyqxmd.com/read/28688624/indirect-decompression-in-spinal-surgery
#19
REVIEW
Hiroyuki Yoshihara
Indirect decompression in spinal surgery means decompression of spinal nerve tissues, such as spinal cord and nerve, without resecting the compressing tissue. Indirect spinal decompression procedures largely can be divided into segmental procedures and global spinal alignment procedures. Segmental procedures are mainly performed by the distraction between two vertebrae, which lead to the opening of the neural foramen and increases the epidural space. Such distraction can be performed through the disc space or using posterior instrumentation...
July 5, 2017: Journal of Clinical Neuroscience: Official Journal of the Neurosurgical Society of Australasia
https://www.readbyqxmd.com/read/28686948/posterior-communicating-artery-aneurysms-causing-facial-pain-a-comprehensive-review
#20
REVIEW
Javier Ros de San Pedro
Posterior communicating aneurysms are commonly associated with oculomotor nerve palsy. However, trigeminal nerve involvement among these aneurysms is a rare event with no previous analysis. In order to describe the main features of posterior communicating aneurysms causing trigeminal neuralgia (TGN-PComAAs) eight cases (six from the literature plus two more illustrative cases) were included in the present series. All cases were thoroughly studied in order to collect their epidemiological, radiological, clinical, therapeutic, pathogenic, and outcome data...
June 23, 2017: Clinical Neurology and Neurosurgery
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