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https://www.readbyqxmd.com/read/28314573/decreased-incidence-of-end-stage-renal-disease-in-american-indians-with-diabetes-a-model-for-other-high-risk-populations
#1
Christina M Wyatt
Indigenous populations in North America have very high rates of diabetes and diabetic complications, including end-stage renal disease. A promising new report demonstrates a substantial decline in the incidence of diabetic end-stage renal disease among American Indians and Alaska Natives, coinciding with a public health intervention targeting diabetes management in this population. This success may offer a model for interventions to improve kidney disease outcomes in other high-risk populations.
April 2017: Kidney International
https://www.readbyqxmd.com/read/28300324/risk-of-stress-fracture-varies-by-race-ethnic-origin-in-a-cohort-study-of-1-3-million-u-s-army-soldiers
#2
Lakmini Bulathsinhala, Julie M Hughes, Craig J McKinnon, Joseph R Kardouni, Katelyn I Guerriere, Kristin L Popp, Ronald W Matheny, Mary L Bouxsein
Stress fractures (SF) are common and costly injuries in military personnel. Risk for SF has been shown to vary with race/ethnicity. Previous studies report increased SF risk in White and Hispanic Soldiers compared to Black soldiers. However, these studies did not account for the large ethnic diversity in the U.S. Military. PURPOSE: We aimed to identify differences in SF risk among racial/ethnic groups within the U.S. Army. METHODS: A retrospective cohort study was conducted using data from the Total Army Injury and Health Outcomes Database from 2001 until 2011...
March 16, 2017: Journal of Bone and Mineral Research: the Official Journal of the American Society for Bone and Mineral Research
https://www.readbyqxmd.com/read/28298840/the-need-for-a-population-based-dose-optimization-study-for-recombinant-tissue-plasminogen-activator-in-acute-ischemic-stroke-a-study-from-a-tertiary-care-teaching-hospital-from-south-india
#3
Siju V Abraham, Fazil Thaha, S Vimal Krishnan, Athulya Shajan, Jayaraj Mymbilly Balakrishnan, Babu Urumese Palatty
CONTEXT: The guideline recommended dose of intravenous (i.v) recombinant tissue-type plasminogen activator (rt-PA) for acute ischemic stroke is 0.9 mg/kg in the European and American populations. In Asiatic population, some studies have shown that a lower dose of i.v rt-PA is equally efficacious. AIMS: To assess if there is a need for a dose optimization for i.v rt-PA study among Indians. SETTING AND DESIGN: A prospective, observational database of acute stroke cases that presented to a tertiary care institute over a period of 1 year was made...
January 2017: Annals of Indian Academy of Neurology
https://www.readbyqxmd.com/read/28292501/indian-health-service-pharmacists-engaged-in-opioid-safety-initiatives-and-expanding-access-to-naloxone
#4
Hillary Duvivier, Samantha Gustafson, Morgan Greutman, Tenzin Jangchup, Ashlee Knapp Harden, Aimee Reinhard, Keith Warshany
OBJECTIVE: To develop effective pharmacy-based interventions to mitigate harm from opioid use disorders. Programs include responsible opioid prescribing, expanded access to medication-assisted treatment (MAT), naloxone, and community interventions. SETTING: Clinical pharmacists practicing at Indian Health Service (IHS) locations in the Southwest, Midwest, and Great Lakes regions. These pharmacists serve culturally diverse American Indian populations throughout the United States and interface with tribal and federal programs to impact the opioid epidemic in Indian Country...
March 2017: Journal of the American Pharmacists Association: JAPhA
https://www.readbyqxmd.com/read/28289486/a-research-experience-for-american-indian-undergraduates-utilizing-an-actor-partner-interdependence-model-to-examine-the-student-mentor-dyad
#5
Emily R Griese, Tracey R McMahon, DenYelle Baete Kenyon
The majority of research examining Undergraduate Research Experiences focuses singularly on student-reported outcomes, often overlooking assessment of the mentor role in student learning and outcomes following these experiences. The goal of the current study was to examine the student-mentor dyad at the beginning and end of a 10-week summer research experience for American Indian undergraduates utilizing a series of actor-partner interdependence models within SEM. Participants included 26 undergraduate interns (50% American Indian; 50% American Indian and White; M age = 24) and 27 mentors (89% White; M age = 47)...
March 2017: Journal of Diversity in Higher Education
https://www.readbyqxmd.com/read/28282529/evidence-of-socio-economic-stress-and-female-foeticide-in-racial-disparities-in-the-gender-ratio-at-birth-in-the-united-states-1995-2014
#6
Victor Grech
BACKGROUND: Males are born in excess of females, expressed as M/T (male/total births), which is expected to approximate 0.515. Racial M/T disparities have been long known. This study was carried out in order to identify such disparities in different races in the United States. DESIGN: Monthly male and female live births by race for the entire US were obtained from the website of the Centers for Disease Control and Prevention for 1995-2014 for the four racial groups: American Indian or Alaska Native, Asian or Pacific Islander, Black or African American and White...
March 1, 2017: Early Human Development
https://www.readbyqxmd.com/read/28282303/diversity-in-the-emerging-critical-care-workforce-analysis-of-demographic-trends-in-critical-care-fellows-from-2004-to-2014
#7
Meghan B Lane-Fall, Todd A Miano, Jaya Aysola, John G T Augoustides
OBJECTIVES: Diversity in the physician workforce is essential to providing culturally effective care. In critical care, despite the high stakes and frequency with which cultural concerns arise, it is unknown whether physician diversity reflects that of critically ill patients. We sought to characterize demographic trends in critical care fellows, who represent the emerging intensivist workforce. DESIGN: We used published data to create logistic regression models comparing annual trends in the representation of women and racial/ethnic groups across critical care fellowship types...
March 9, 2017: Critical Care Medicine
https://www.readbyqxmd.com/read/28281490/evidence-based-guidelines-for-the-management-of-epilepsy
#8
REVIEW
Sanjay P Singh, Ram Sankaraneni, Arun R Antony
Approximately 50 million people live with epilepsy worldwide. The aim of this review is to present an overview of the current evidence and management recommendations for evaluation and treatment of patients with epilepsy. Systematic literature reviews were undertaken. A review of contemporary published evidence-based guidelines (American Academy of Neurology, American Epilepsy Society, and the Indian Epilepsy Society) and published peer reviewed scientific publications was done. The guideline is addressed to all clinicians who manage epilepsy patients...
2017: Neurology India
https://www.readbyqxmd.com/read/28276881/the-association-of-remotely-sensed-outdoor-fine-particulate-matter-with-cancer-incidence-of-respiratory-system-in-the-usa
#9
Ashraf Z Al-Hamdan, Reem N Albashaireh, Mohammad Z Al-Hamdan, William L Crosson
This study aimed to assess the association between exposure to fine particulate matter (PM2.5) and respiratory system cancer incidence in the US population (n = 295,404,580) using a satellite-derived estimate of PM2.5 concentrations. Linear and logistic regression analyses were performed to determine whether PM2.5 was related to the odds of respiratory system cancer (RSC) incidence based on gender and race. Positive linear regressions were found between PM2.5 concentrations and the age-adjusted RSC incidence rates for all groups (Males, Females, Whites, and Blacks) except for Asians and American Indians...
February 28, 2017: Journal of Environmental Science and Health. Part A, Toxic/hazardous Substances & Environmental Engineering
https://www.readbyqxmd.com/read/28271422/the-obesity-epidemic-in-the-veterans-health-administration-prevalence-among-key-populations-of-women-and-men-veterans
#10
Jessica Y Breland, Ciaran S Phibbs, Katherine J Hoggatt, Donna L Washington, Jimmy Lee, Sally Haskell, Uchenna S Uchendu, Fay S Saechao, Laurie C Zephyrin, Susan M Frayne
BACKGROUND: Most US adults are overweight or obese. Understanding differences in obesity prevalence across subpopulations could facilitate the development and dissemination of weight management services. OBJECTIVES: To inform Veterans Health Administration (VHA) weight management initiatives, we describe obesity prevalence among subpopulations of VHA patients. DESIGN: Cross-sectional descriptive analyses of fiscal year 2014 (FY2014) national VHA administrative and clinical data, stratified by gender...
March 7, 2017: Journal of General Internal Medicine
https://www.readbyqxmd.com/read/28266760/race-related-differences-in-tissue-dielectric-constant-measured-noninvasively-at-300%C3%A2-mhz-in-male-and-female-skin-at-multiple-sites-and-depths
#11
H N Mayrovitz, S A Mahtani, E Pitts, L Michaelos
BACKGROUND/PURPOSE: We hypothesized that reported race-related differences in skin properties cause skin and skin-to-fat water differences among races that are measureable by skin tissue dielectric constant (TDC) values that depend strongly on water content. Our first aim was to test this hypothesis. Also, since inter-side TDC ratios are used to assess edema and lymphedema, the second aim was to test if TDC ratios are race-dependent. The third aim was to determine the extent to which TDC depends on total body water (TBW) and fat (TBF)...
March 7, 2017: Skin Research and Technology
https://www.readbyqxmd.com/read/28263280/disparities-in-potentially-preventable-hospitalizations-between-american-indian-and-alaska-native-and-non-hispanic-white-medicare-enrollees
#12
Joan O'Connell, Jennifer Rockell, Judith C Ouellet, Mark LeBeau
OBJECTIVE: A number of health care initiatives seek to improve health outcomes by increasing access to outpatient services while reducing preventable acute events. We evaluated disparities between American Indian and Alaska Native (AI/AN) and non-Hispanic white (white) Medicare enrollees in access to outpatient preventive, primary, and specialty services by comparing their potentially preventable hospitalizations (PPHs). RESEARCH DESIGN: The study population included 121,311 adult AI/AN Medicare enrollees registered to use services funded by the Indian Health Service and 5,915,011 adult white enrollees living in the same counties...
March 3, 2017: Medical Care
https://www.readbyqxmd.com/read/28262088/genome-wide-association-study-of-post-traumatic-stress-disorder-in-two-high-risk-populations
#13
Whitney E Melroy-Greif, Kirk C Wilhelmsen, Rachel Yehuda, Cindy L Ehlers
Mexican Americans (MAs) and American Indians (AIs) constitute conspicuously understudied groups with respect to risk for post-traumatic stress disorder (PTSD), especially in light of findings showing racial/ethnic differences in trauma exposure and risk for PTSD. The purpose of this study was to examine genetic influences on PTSD in two minority cohorts. A genome-wide association study (GWAS) with sum PTSD symptoms for trauma-exposed subjects was run in each cohort. Six highly correlated variants in olfactory receptor family 11 subfamily L member 1 (OR11L1) were suggestively associated with PTSD in the MA cohort...
March 6, 2017: Twin Research and Human Genetics: the Official Journal of the International Society for Twin Studies
https://www.readbyqxmd.com/read/28259877/findings-of-vascular-brain-injury-and-structural-loss-from-cranial-magnetic-resonance-imaging-in-elderly-american-indians-the-strong-heart-study
#14
Astrid M Suchy-Dicey, Dean K Shibata, Tara M Madhyastha, Thomas J Grabowski, W T Longstreth, Dedra S Buchwald
BACKGROUND: The Cerebrovascular Disease and its Consequences in American Indians study conducted cranial MRI examination of surviving participants of the Strong Heart Study, a longitudinal cohort of elderly American Indians. METHODS: Of the 1,033 recruited participants, some were unable to complete the MRI (n = 22), some scans were unusable due to participant motion or technical errors (n = 13), and one community withdrew consent after data collection (n = 209), leaving 789 interpretable MRI scan images...
March 4, 2017: Neuroepidemiology
https://www.readbyqxmd.com/read/28256284/human-papillomavirus-vaccine-uptake-increase-for-american-indian-adolescents-2013-2015
#15
Jasmine L Jacobs-Wingo, Cheyenne C Jim, Amy V Groom
INTRODUCTION: Although Indian Health Service, tribally-operated, and urban Indian (I/T/U) healthcare facilities have higher human papillomavirus (HPV) vaccine series initiation and completion rates among adolescent patients aged 13-17 years than the general U.S. population, challenges remain. I/T/U facilities have lower coverage for HPV vaccine first dose compared with coverage for other adolescent vaccines, and HPV vaccine series completion rates are lower than initiation rates. Researchers aimed to assist I/T/U facilities in identifying interventions to increase HPV vaccination series initiation and completion rates...
February 27, 2017: American Journal of Preventive Medicine
https://www.readbyqxmd.com/read/28252556/predictors-for-patient-discharge-destination-following-elective-anterior-cervical-discectomy-and-fusion
#16
John Di Capua, Sulaiman Somani, Jun S Kim, Nathan J Lee, Parth Kothari, Kevin Phan, Nahyr Lugo-Fagundo, Samuel K Cho
STUDY DESIGN: Retrospective study of prospectively collected data. OBJECTIVE: To identify risk factors for non-home patient discharge following elective anterior cervical discectomy and fusion (ACDF). SUMMARY OF BACKGROUND DATA: ACDF is one of the most performed spinal procedures and this is expected to increase in the coming years. In order to effectively deal with an increasing patient volume, identifying variables associated with patient discharge destination can expedite placement applications and subsequently reduce hospital length of stay...
March 1, 2017: Spine
https://www.readbyqxmd.com/read/28250479/consensus-statement-on-anaesthesia-for-day-care-surgeries
#17
REVIEW
Satish Kulkarni, S S Harsoor, M Chandrasekar, S Bala Bhaskar, Jitendra Bapat, Edakeparavan Keloth Ramdas, Umesh Kumar Valecha, Amol Shashikumar Pradhan, Adarsh Chandra Swami
The primary aim of day-care surgery units is to allow for early recovery of the patients so that they can return to their familiar 'home' environment; the management hence should be focused towards achieving these ends. The benefits could include a possible reduction in the risk of thromboembolism and hospital-acquired infections. Furthermore, day-care surgery is believed to reduce the average unit cost of treatment by up to 70% as compared to inpatient surgery. With more than 20% of the world's disease burden, India only has 6% of the world's hospital beds...
February 2017: Indian Journal of Anaesthesia
https://www.readbyqxmd.com/read/28249607/molecular-typing-of-mycobacterium-tuberculosis-complex-isolated-from-pulmonary-tuberculosis-patients-in-central-ethiopia
#18
Zufan Bedewi, Adane Worku, Yalemtsehay Mekonnen, Getnet Yimer, Girmay Medhin, Gezahegne Mamo, Rembert Pieper, Gobena Ameni
BACKGROUND: Identification of the types of strains of Mycobacterium tuberculosis (M. tuberculosis) complex causing tuberculosis (TB) could contribute to TB control program of specific geographic region as well as it could add knowledge onto the existing literature on TB worldwide. The objective of the present study was to identify the species and strains of M. tuberculosis complex causing pulmonary tuberculosis in central Ethiopia. METHODS: A health institution- based cross-sectional study was conducted on 338 smear positive TB cases visiting three hospitals between October 2012 and September 2013...
March 1, 2017: BMC Infectious Diseases
https://www.readbyqxmd.com/read/28242106/possible-role-of-rare-variants-in-trace-amine-associated-receptor-1-in-schizophrenia
#19
Jibin John, Prachi Kukshal, Triptish Bhatia, K V Chowdari, V L Nimgaonkar, S N Deshpande, B K Thelma
Schizophrenia (SZ) is a chronic mental illness with behavioral abnormalities. Recent common variant based genome wide association studies and rare variant detection using next generation sequencing approaches have identified numerous variants that confer risk for SZ, but etiology remains unclear propelling continuing investigations. Using whole exome sequencing, we identified a rare heterozygous variant (c.545G>T; p.Cys182Phe) in Trace amine associated receptor 1 gene (TAAR1 6q23.2) in three affected members in a small SZ family...
February 24, 2017: Schizophrenia Research
https://www.readbyqxmd.com/read/28241775/rigorous-evaluation-of-a-pregnancy-prevention-program-for-american-indian-youth-and-adolescents-study-protocol-for-a-randomized-controlled-trial
#20
Lauren Tingey, Rachel Chambers, Novalene Goklish, Francene Larzelere, Angelita Lee, Rosemarie Suttle, Summer Rosenstock, Kristin Lake, Allison Barlow
BACKGROUND: American Indian adolescents have one of the highest rates of teen pregnancy and repeat teen births in the US. Substance use is a significant risk factor for unprotected sex, and American Indian adolescents have the highest substance use-related morbidity and mortality of any US racial group. Despite these disparities, there are no existing, evidence-based programs for pregnancy prevention that have been rigorously evaluated among American Indian teens. METHODS: The proposed study is a randomized controlled trial to test the efficacy of a comprehensive sexual and reproductive health program developed in partnership with an American Indian community...
February 27, 2017: Trials
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