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https://www.readbyqxmd.com/read/29453031/spaces-of-hope-youth-perspectives-on-health-and-wellness-in-indigenous-communities
#1
Lydia Wood, David Kamper, Kate Swanson
This article addresses an apparent paradox between academic and policy depictions of American Indian reservations as "broken" and "unhealthy" places, and Indigenous youth perceptions of reservations as spaces of "health" and "wellness." Public health literature often frames reservations as damaged, health-denying places, chronicling the extraordinarily high rates of suicide, substance abuse, as well as vast health disparities. Despite these dire statistics, our research with Native youth in San Diego County found that young people chose to primarily emphasize their positive experiences with, and attachments to, their reservations...
February 13, 2018: Health & Place
https://www.readbyqxmd.com/read/29449100/hepatitis-a-vaccination-coverage-among-adolescents-13-17-years-in-the-united-states-2008-2016
#2
Noele P Nelson, David Yankey, James A Singleton, Laurie D Elam-Evans
BACKGROUND: The hepatitis A (HepA) vaccine was recommended by the Advisory Committee on Immunization Practices (ACIP) incrementally from 1996 to 1999. In 2006, HepA vaccine was recommended (1) universally for children aged 12-23 months, (2) for persons who are at increased risk for infection, or (3) for any person wishing to obtain immunity. Catch-up vaccination can be considered. OBJECTIVE: To assess HepA vaccine coverage among adolescents and factors independently associated with vaccination administration in the US...
February 12, 2018: Vaccine
https://www.readbyqxmd.com/read/29445940/differences-in-breast-cancer-incidence-among-young-women-aged-20-49-years-by-stage-and-tumor-characteristics-age-race-and-ethnicity-2004-2013
#3
Meredith L Shoemaker, Mary C White, Manxia Wu, Hannah K Weir, Isabelle Romieu
PURPOSE: Younger women diagnosed with breast cancer have poorer prognoses and higher mortality compared to older women. Young black women have higher incidence rates of breast cancer and more aggressive subtypes than women of other races/ethnicities. In this study, we examined recent trends and variations in breast cancer incidence among young women in the United States. METHODS: Using 2004-2013 National Program of Cancer Registries and Surveillance, Epidemiology, and End Results Program data, we calculated breast cancer incidence rates and trends and examined variations in stage, grade, and tumor subtype by age and race/ethnicity among young women aged 20-49 years...
February 14, 2018: Breast Cancer Research and Treatment
https://www.readbyqxmd.com/read/29445423/an-update-on-vitamin-b12-related-gene-polymorphisms-and-b12-status
#4
REVIEW
S Surendran, A Adaikalakoteswari, P Saravanan, I A Shatwaan, J A Lovegrove, K S Vimaleswaran
Background: Vitamin B12 is an essential micronutrient in humans needed for health maintenance. Deficiency of vitamin B12 has been linked to dietary, environmental and genetic factors. Evidence for the genetic basis of vitamin B12 status is poorly understood. However, advancements in genomic techniques have increased the knowledge-base of the genetics of vitamin B12 status. Based on the candidate gene and genome-wide association (GWA) studies, associations between genetic loci in several genes involved in vitamin B12 metabolism have been identified...
2018: Genes & Nutrition
https://www.readbyqxmd.com/read/29439613/occurrence-of-endocrine-and-thyroid-cancers-among-alaska-native-people-1969-2013
#5
Sarah H Nash, Anne P Lanier, Molly B Southworth
BACKGROUND: Nationwide, the incidence of thyroid cancer is lower among American Indian/Alaska Native (AI/AN) people than among U.S. whites (USW). However, little is known about the incidence of thyroid, or other endocrine cancers specifically among Alaska Native (AN) people. METHODS: We examined data from the National Cancer Institute's (NCI) Surveillance Epidemiology and End Results (SEER) Alaska Native Tumor Registry on endocrine cancers diagnosed among AN people from 1969-2013, with a specific focus on thyroid cancers...
February 14, 2018: Thyroid: Official Journal of the American Thyroid Association
https://www.readbyqxmd.com/read/29436156/cytochrome-p450-genetic-variation-associated-with-tamoxifen-biotransformation-in-american-indian-and-alaska-native-people
#6
Burhan A Khan, Renee Robinson, Alison E Fohner, LeeAnna I Muzquiz, Brian D Schilling, Julie A Beans, Matthew J Olnes, Laura Trawicki, Holly Frydenlund, Cindi Laukes, Patrick Beatty, Brian Phillips, Deborah Nickerson, Kevin Howlett, Denise A Dillard, Timothy A Thornton, Kenneth E Thummel, Erica L Woodahl
Despite evidence that pharmacogenetics can improve tamoxifen pharmacotherapy, there are few studies with American Indian and Alaska Native (AIAN) people. We examined variation in cytochrome P450 (CYP) genes (CYP2D6, CYP3A4, CYP3A5, and CYP2C9) and tamoxifen biotransformation in AIAN patients with breast cancer (n = 42) from the Southcentral Foundation in Alaska and the Confederated Salish and Kootenai Tribes in Montana. We tested for associations between CYP diplotypes and plasma concentrations of tamoxifen and metabolites...
February 13, 2018: Clinical and Translational Science
https://www.readbyqxmd.com/read/29435930/quantum-language-of-microrna-application-for-new-cancer-therapeutic-targets
#7
Yoichi Robertus Fujii
MicroRNA (miRNA) is the noncoding gene: therefore, the miRNA gene inheritably controls protein gene expression through transcriptional and post-transcriptional levels. Aberrant expression of miRNA genes causes various human diseases, especially cancers. Although cancer is a complex disease, cancer/miRNA implication has yet been grasped from the perspective of miRNA profile in bed side. Since miRNA is the mobile genetic element, the clinical verification of miRNA in microvesicle of blood is too much straggle to predict potential cancer/miRNA associations without bioinformatical computing...
2018: Methods in Molecular Biology
https://www.readbyqxmd.com/read/29435862/disparities-in-the-treatment-of-substance-use-disorders-does-where-you-live-matter
#8
Andrea Acevedo, Lee Panas, Deborah Garnick, Dolores Acevedo-Garcia, Jennifer Miles, Grant Ritter, Kevin Campbell
This study focused on (1) whether disparities in timely receipt of substance use services can be explained in part by the characteristics of the community in which the clients reside and (2) whether the effect of community characteristics on timely receipt of services was similar across racial/ethnic groups. The sample was composed of adults receiving publicly funded outpatient treatment in Washington State. Treatment data were linked to data from the US census. The outcome studied was "Initiation and Engagement" in treatment (IET), a measure noting timely receipt of services at the beginning of treatment...
February 12, 2018: Journal of Behavioral Health Services & Research
https://www.readbyqxmd.com/read/29435785/adverse-childhood-experiences-and-postpartum-depression-in-home-visiting-programs-prevalence-association-and-mediating-mechanisms
#9
Joshua P Mersky, Colleen E Janczewski
Objectives In this study, we examined the prevalence of postpartum depression (PPD) and its association with select demographic factors and antenatal conditions. We also investigated whether greater exposure to adverse childhood experiences (ACEs) is associated with PPD, and if antenatal conditions mediate the ACE-PPD relationship. Methods Data were collected from 735 low-income women receiving home visiting services. Descriptive and bivariate analyses provided estimates of PPD and its correlates, and nested path analyses were used to test for mediation...
February 12, 2018: Maternal and Child Health Journal
https://www.readbyqxmd.com/read/29432662/associations-of-overweight-obesity-and-socioeconomic-status-with-hypertension-prevalence-across-racial-and-ethnic-groups
#10
Deborah Rohm Young, Heidi Fischer, David Arterburn, Daniel Bessesen, Lee Cromwell, Matthew F Daley, Jay Desai, Assiamira Ferrara, Stephanie L Fitzpatrick, Michael A Horberg, Corinna Koebnick, Claudia L Nau, Caryn Oshiro, Beth Waitzfelder, Ayae Yamamoto
Racial/ethnic disparities in the prevalence of diagnosed hypertension are persistent but may be partially explained by racial/ethnic differences in weight category and neighborhood socioeconomic status. The authors compared hypertension prevalence rates among 4 060 585 adults with overweight or obesity across 10 healthcare systems by weight category and neighborhood education level in geographically and racially diverse individuals. Data were obtained from electronic health records. Hypertension was defined as at least two outpatient visits or one inpatient hospitalization with a coded diagnosis...
February 12, 2018: Journal of Clinical Hypertension
https://www.readbyqxmd.com/read/29427130/prevalence-and-indicators-of-household-smoking-bans-among-american-indians
#11
Ashley Comiford, Eva Garroutte, Celestina Barbosa-Leiker, Sixia Chen, Michael McDonell
More than 58 million nonsmokers in the U.S. encounter secondhand smoke that leads to tobacco-related diseases and deaths every year, making voluntary household smoking bans an important public health goal. American Indians/Alaska Natives are rarely included in research related to household smoking bans. Further, most studies dichotomize household smoking bans into complete bans versus partial/no bans, rendering it impossible to determine if partial and no bans are associated with different or similar risk factors...
February 9, 2018: Journal of Community Health
https://www.readbyqxmd.com/read/29426597/determinants-of-tuberculosis-trends-in-six-indigenous-populations-of-the-usa-canada-and-greenland-from-1960-to-2014-a-population-based-study
#12
Kianoush Dehghani, Zhiyi Lan, Peizhi Li, Sascha Wilk Michelsen, Sean Waites, Andrea Benedetti, Pierre Lejeune, Jill Torrie, Elizabeth Robinson, Berenica Vejvoda, Muhammad Mullah, Diana Redwood, Michael Cooper, Anne Fanning, Wadieh Yacoub, Gonzalo G Alvarez, Bolette Søborg, Richard Long, Dick Menzies
BACKGROUND: Tuberculosis continues to disproportionately affect many Indigenous populations in the USA, Canada, and Greenland. We aimed to investigate whether population-based tuberculosis-specific interventions or changes in general health and socioeconomic indicators, or a combination of these factors, were associated with changes in tuberculosis incidence in these Indigenous populations. METHODS: For this population-based study we examined annual tuberculosis notification rates between 1960 and 2014 in six Indigenous populations of the USA, Canada, and Greenland (Inuit [Greenland], American Indian and Alaska Native [Alaska, USA], First Nations [Alberta, Canada], Cree of Eeyou Istchee [Quebec, Canada], Inuit of Nunavik [Quebec, Canada], and Inuit of Nunavut [Canada]), as well as the general population of Canada...
February 6, 2018: Lancet. Public Health
https://www.readbyqxmd.com/read/29425063/psychotropic-medication-patterns-for-american-indian-children-in-foster-care
#13
David Glesener, Gwendolyn Anderson, Xuan Li, Jacob Brown, James Amell, Ronald Regal, Donald Ferguson
OBJECTIVE: This study assesses the effects of race, age, sex, and time spent in foster care on rates of psychotropic medication use for children in foster care in 2012. METHODS: Using existing electronic records through county Social Service and Minnesota Medical Assistance databases, 626 children were identified using the inclusion criteria of having been in foster care for at least 30 days during 2012 in St. Louis County, Minnesota. All prescriptions for dispensed psychotropic medications were identified into the following classes: antidepressants, attention-deficit/hyperactivity disorder (ADHD) medications, antipsychotics, alpha-agonists, and other (including anticonvulsants/mood stabilizers, lithium, benzodiazepines, and sedative hypnotics)...
February 9, 2018: Journal of Child and Adolescent Psychopharmacology
https://www.readbyqxmd.com/read/29417315/physical-activity-and-telomere-length-in-american-indians-the-strong-heart-study
#14
Amanda M Fretts, Mihriye Mete, Barbara V Howard, Lyle G Best, David S Siscovick, Sigal Eilat-Adar, Jinying Zhao
Telomere length, a marker of biological aging, has been associated with many chronic diseases, but its relations with physical activity remains unclear. The purpose of this study was to examine the association of objectively measured ambulatory activity with leukocyte telomere length (LTL), a marker of biological aging, among American Indians. This cross-sectional study included 2312 AI participants from the Strong Heart Family Study. Steps per day were measured using Accusplit AE120 pedometers. Quantitative PCR was used to measure LTL...
February 7, 2018: European Journal of Epidemiology
https://www.readbyqxmd.com/read/29416899/genotypic-characterization-and-comparison-of-streptococcus-mutans-in-american-indian-and-southeast-iowa-children
#15
Alissa L Villhauer, David J Lynch, John J Warren, Deborah V Dawson, Derek R Blanchette, David R Drake
Early childhood caries is a complex health care issue that has a multifactorial etiology. One aspect of this etiology is the colonization and propagation of acidogenic bacteria at an early age. There have been several bacterial species associated with caries but 1 common species is Streptococcus mutans. Here, we describe genotypic diversity and commonality of Streptococcus mutans recovered from children representing 2 groups with similar socioeconomic demographics: a Northern Plains American Indian Tribe and a Southeast Iowa population...
December 2017: Clinical and Experimental Dental Research
https://www.readbyqxmd.com/read/29413094/vaccine-preventable-hospitalizations-among-american-indian-alaska-native-children-using-the-2012-kid-s-inpatient-database
#16
Amanda J Nickel, Susan E Puumala, Anupam B Kharbanda
Our aim was to assess the odds of hospitalization for a vaccine-preventable, infectious disease (VP-ID) in American Indian/Alaska Native (AI/AN) children compared to other racial and ethnic groups using the 2012 Kid's Inpatient Database (KID) The KID is a nationally representative sample, which allows for evaluation of VP-ID in a non-federal, non-Indian Health Service setting. In a cross-sectional analysis, we evaluated the association of race/ethnicity and a composite outcome of hospitalization due to vaccine-preventable infection using multivariate logistic regression...
February 8, 2018: Vaccine
https://www.readbyqxmd.com/read/29412713/mortality-disparities-in-racial-ethnic-minority-groups-in-the-veterans-health-administration-an-evidence-review-and-map
#17
Kim Peterson, Johanna Anderson, Erin Boundy, Lauren Ferguson, Ellen McCleery, Kallie Waldrip
BACKGROUND: Continued racial/ethnic health disparities were recently described as "the most serious and shameful health care issue of our time." Although the 2014 US Affordable Care Act-mandated national insurance coverage expansion has led to significant improvements in health care coverage and access, its effects on life expectancy are not yet known. The Veterans Health Administration (VHA), the largest US integrated health care system, has a sustained commitment to health equity that addresses all 3 stages of health disparities research: detection, understanding determinants, and reduction or elimination...
March 2018: American Journal of Public Health
https://www.readbyqxmd.com/read/29412050/polluted-morality-air-pollution-predicts-criminal-activity-and-unethical-behavior
#18
Jackson G Lu, Julia J Lee, Francesca Gino, Adam D Galinsky
Air pollution is a serious problem that affects billions of people globally. Although the environmental and health costs of air pollution are well known, the present research investigates its ethical costs. We propose that air pollution can increase criminal and unethical behavior by increasing anxiety. Analyses of a 9-year panel of 9,360 U.S. cities found that air pollution predicted six major categories of crime; these analyses accounted for a comprehensive set of control variables (e.g., city and year fixed effects, population, law enforcement) and survived various robustness checks (e...
February 1, 2018: Psychological Science
https://www.readbyqxmd.com/read/29389917/surveillance-for-violent-deaths-national-violent-death-reporting-system-18-states-2014
#19
Katherine A Fowler, Shane P D Jack, Bridget H Lyons, Carter J Betz, Emiko Petrosky
PROBLEM/CONDITION: In 2014, approximately 59,000 persons died in the United States as a result of violence-related injuries. This report summarizes data from CDC's National Violent Death Reporting System (NVDRS) regarding violent deaths from 18 U.S. states for 2014. Results are reported by sex, age group, race/ethnicity, marital status, location of injury, method of injury, circumstances of injury, and other selected characteristics. REPORTING PERIOD COVERED: 2014...
February 2, 2018: MMWR. Surveillance Summaries: Morbidity and Mortality Weekly Report. Surveillance Summaries
https://www.readbyqxmd.com/read/29389890/p450-pharmacogenetics-in-indigenous-north-american-populations
#20
REVIEW
Lindsay M Henderson, Katrina G Claw, Erica L Woodahl, Renee F Robinson, Bert B Boyer, Wylie Burke, Kenneth E Thummel
Indigenous North American populations, including American Indian and Alaska Native peoples in the United States, the First Nations, Métis and Inuit peoples in Canada and Amerindians in Mexico, are historically under-represented in biomedical research, including genomic research on drug disposition and response. Without adequate representation in pharmacogenetic studies establishing genotype-phenotype relationships, Indigenous populations may not benefit fully from new innovations in precision medicine testing to tailor and improve the safety and efficacy of drug treatment, resulting in health care disparities...
February 1, 2018: Journal of Personalized Medicine
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