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https://www.readbyqxmd.com/read/28728763/implementation-of-a-school-nurse-led-intervention-for-children-with-severe-obesity-in-new-york-city-schools
#1
Krista Schroeder, Haomiao Jia, Y Claire Wang, Arlene Smaldone
PURPOSE: The Healthy Options and Physical Activity Program (HOP) is a school nurse-led intervention for children with severe obesity. HOP was developed by experts at the New York City Department of Health and Mental Hygiene and implemented in New York City schools beginning in 2012. The purpose of this study was to evaluate HOP implementation with the goal of informing HOP refinement and potential future HOP dissemination. DESIGN AND METHODS: This study entailed a retrospective analysis of secondary data...
July 2017: Journal of Pediatric Nursing
https://www.readbyqxmd.com/read/28728075/immunological-tolerance-as-a-barrier-to-protective-hiv-humoral-immunity
#2
REVIEW
Kristin Ms Schroeder, Amanda Agazio, Raul M Torres
HIV-1 infection typically eludes antibody control by our immune system and is not yet prevented by a vaccine. While many viral features contribute to this immune evasion, broadly neutralizing antibodies (bnAbs) against HIV-1 are often autoreactive and it has been suggested that immunological tolerance may restrict a neutralizing antibody response. Indeed, recent Ig knockin mouse studies have shown that bnAb-expressing B cells are largely censored by central tolerance in the bone marrow. However, the contribution of peripheral tolerance in limiting the HIV antibody response by anergic and potentially protective B cells is poorly understood...
July 17, 2017: Current Opinion in Immunology
https://www.readbyqxmd.com/read/28727061/behavior-of-immunologically-castrated-barrows-in-comparison-to-gilts-physically-castrated-barrows-and-intact-male-pigs
#3
C L Puls, A Rojo, P D Matzat, A L Schroeder, M Ellis
The behavior of immunologically castrated barrows (IC; with Improvest; Zoetis, Parsippany, NJ) was compared with that of intact males (IM), physically castrated barrows (PC), and gilts (G). The study used 160 commercial crossbred pigs in a randomized complete block design (blocking factor was start date of study) and was performed over an 8-wk period from 16 wk of age (67.2 ± 2.50 kg BW) to a final BW of 126.5 ± 6.05 kg. The first Improvest dose was given to IC at the start of the study (d 0), and the second dose was given 28 d later...
June 2017: Journal of Animal Science
https://www.readbyqxmd.com/read/28724064/genetic-characterization-of-the-soybean-nested-association-mapping-population
#4
Qijian Song, Long Yan, Charles Quigley, Brandon D Jordan, Edward Fickus, Steve Schroeder, Bao-Hua Song, Yong-Qiang Charles An, David Hyten, Randall Nelson, Katy Rainey, William D Beavis, Jim Specht, Brian Diers, Perry Cregan
A set of nested association mapping (NAM) families was developed by crossing 40 diverse soybean [ (L.) Merr.] genotypes to the common cultivar. The 41 parents were deeply sequenced for SNP discovery. Based on the polymorphism of the single-nucleotide polymorphisms (SNPs) and other selection criteria, a set of SNPs was selected to be included in the SoyNAM6K BeadChip for genotyping the parents and 5600 RILs from the 40 families. Analysis of the SNP profiles of the RILs showed a low average recombination rate...
July 2017: Plant Genome
https://www.readbyqxmd.com/read/28722685/neural-control-of-finger-movement-via-intracortical-brain-machine-interface
#5
Zachary T Irwin, Karen E Schroeder, Philip P Vu, Autumn J Bullard, Derek M Tat, Chrono S Nu, Alex Vaskov, Samuel R Nason, David E Thompson, Nicole Bentley, Parag G Patil, Cynthia A Chestek
OBJECTIVE: Intracortical brain-machine interfaces (BMIs) are a promising source of prosthesis control signals for individuals with severe motor disabilities. Previous BMI studies have primarily focused on predicting and controlling whole-arm movements; precise control of hand kinematics, however, has not been fully demonstrated. Here, we investigate the continuous decoding of precise finger movements in rhesus macaques. APPROACH: In order to elicit precise and repeatable finger movements, we have developed a novel behavioral task paradigm which requires the subject to acquire virtual fingertip position targets...
July 19, 2017: Journal of Neural Engineering
https://www.readbyqxmd.com/read/28721462/-outpatient-specialist-treatment-%C3%A2-%C3%A2-116b-new-changes-pending-in-outpatient-uro-oncology
#6
REVIEW
A Schroeder
No abstract text is available yet for this article.
July 18, 2017: Der Urologe. Ausg. A
https://www.readbyqxmd.com/read/28720433/single-channel-planar-lipid-bilayer-recordings-of-the-melittin-variant-melp5
#7
Aziz Fennouri, Simon Finn Mayer, Thomas B H Schroeder, Michael Mayer
MelP5 is a 26 amino acid peptide derived from melittin, the main active constituent of bee venom, with five amino acid replacements. The pore-forming activity of MelP5 in lipid membranes is attracting attention because MelP5 forms larger pores and induces dye leakage through liposome membranes at a lower concentration than melittin. Studies of MelP5 have so far focused on ensemble measurements of membrane leakage and impedance; here we extend this characterization with an electrophysiological comparison between MelP5 and melittin using planar lipid bilayer recordings...
July 15, 2017: Biochimica et Biophysica Acta
https://www.readbyqxmd.com/read/28720185/statin-therapy-in-low-risk-air-force-aviators-with-isolated-hypercholesterolemia
#8
Anthony P Tvaryanas, Heather J Mahaney, Valarie M Schroeder, Genny M Maupin
INTRODUCTION: This study evaluated the use of statin therapy in U.S. Air Force (USAF) aviators with isolated hypercholesterolemia in terms of compliance with clinical practice guidelines (CPGs) and effectiveness in reducing low-density lipoprotein cholesterol (LDL-C) and coronary heart disease (CHD) risk. METHODS: This was a mixed design, 8-yr retrospective study that included 8185 participants with isolated hypercholesterolemia, of which 1458 (17.81%) were prescribed statin monotherapy...
August 1, 2017: Aerospace Medicine and Human Performance
https://www.readbyqxmd.com/read/28719453/reliability-and-clinical-utility-of-the-cards-classification-for-degenerative-spondylolisthesis
#9
Garret L Sobol, Alan Hilibrand, Ashley Davis, Paul Millhouse, John Koerner, Christopher Kepler, Gregory D Schroeder, Jonathan D Krystal, Erik C Olsson, Jeffrey Rihn, David Greg Anderson, Alexander Vaccaro, Kristen Radcliff
STUDY DESIGN: Retrospective cohort study. OBJECTIVE: The objective of this study is to determine the reliability and clinical utility of the of the proposed CARDS classification for degenerative spondylolisthesis. BACKGROUND: The Clinical and Radiographic Degenerative Spondylolisthesis (CARDS) classification system was recently proposed as an alternative to the Meyerding system for classifying degenerative spondylolisthesis (DS). Unlike Meyerding, CARDS considers other relevant radiographic findings such as disk space collapse and segmental kyphosis to stratify DS into 4 radiographically discreet types...
July 17, 2017: Clinical Spine Surgery
https://www.readbyqxmd.com/read/28717724/validation-and-quality-assessment-of-the-kilimanjaro-cancer-registry
#10
Leah L Zullig, Kristin Schroeder, Pilli Nyindo, Theresia Namwai, Elvis Silayo, Angelah Msomba, Michael Oresto Munishi, Francis Karia, Charles Muiruri, John Bartlett, Venance Maro, S Yousuf Zafar
PURPOSE: Global cancer burden has increasingly shifted to low- and middle-income countries and is particularly pronounced in Africa. There remains a lack of comprehensive cancer information as a result of limited cancer registry development. In Moshi, Tanzania, a regional cancer registry exists at Kilimanjaro Christian Medical Center. Data quality is unknown. Our objective was to evaluate the completeness and quality of the Kilimanjaro Cancer Registry (KCR). METHODS: In October 2015, we conducted a retrospective review of KCR by validating the internal consistency of registry records with medical and pathology records...
December 2016: Journal of Global Oncology
https://www.readbyqxmd.com/read/28713655/differential-effect-of-platelet-endothelial-cell-adhesion-molecule-1-pecam-1-on-leukocyte-infiltration-during-contact-hypersensitivity-responses
#11
Merideth Early, William G Schroeder, Ranajana Unnithan, John M Gilchrist, William A Muller, Alan Schenkel
BACKGROUND: 2'-4' Dinitrofluorobenzene (DNFB) induced contact hypersensitivity is an established model of contact sensitivity and leukocyte migration. Platelet Endothelial Cell Adhesion Molecule-1 (PECAM-1) deficient mice were used to examine the role of PECAM-1 in the migration capacity of several different leukocyte populations after primary and secondary application. RESULTS: γδ T lymphocytes, granulocytes, and Natural Killer cells were most affected by PECAM-1 deficiency at the primary site of application...
2017: PeerJ
https://www.readbyqxmd.com/read/28712475/effectiveness-of-acupuncture-therapy-on-stress-in-a-large-urban-college-population
#12
Stefanie Schroeder, James Burnis, Antony Denton, Aaron Krasnow, T S Raghu, Kimberly Mathis
This study is a randomized controlled clinical trial to study the effectiveness of acupuncture on the perception of stress in patients who study or work on a large, urban college campus. The hypothesis was that verum acupuncture would demonstrate a significant positive impact on perceived stress as compared to sham acupuncture. This study included 111 participants with high self-reported stress levels who either studied or worked at a large, urban public university in the southwestern United States. However, only 62 participants completed the study...
June 2017: Journal of Acupuncture and Meridian Studies
https://www.readbyqxmd.com/read/28709615/transcriptional-profiling-of-rickettsia-prowazekii-coding-and-non-coding-transcripts-during-in-vitro-host-pathogen-and-vector-pathogen-interactions
#13
Casey L C Schroeder, Hema P Narra, Abha Sahni, Kamil Khanipov, Jignesh Patel, Yuriy Fofanov, Sanjeev K Sahni
Natural pathogen transmission of Rickettsia prowazekii, the etiologic agent of epidemic typhus, to humans is associated with arthropods, including human body lice, ticks, and ectoparasites of eastern flying squirrel. Recently, we have documented the presence of small RNAs in Rickettsia species and expression of R. prowazekii sRNAs during infection of cultured human microvascular endothelial cells (HMECs), which represent the primary target cells during human infections. Bacterial noncoding transcripts are now well established as critical post-transcriptional regulators of virulence and adaptation mechanisms in varying host environments...
June 29, 2017: Ticks and Tick-borne Diseases
https://www.readbyqxmd.com/read/28707923/quantum-griffiths-phase-inside-the-ferromagnetic-phase-of-ni_-1-x-v_-x
#14
Ruizhe Wang, Adane Gebretsadik, Sara Ubaid-Kassis, Almut Schroeder, Thomas Vojta, Peter J Baker, Francis L Pratt, Stephen J Blundell, Tom Lancaster, Isabel Franke, Johannes S Möller, Katharine Page
We study by means of bulk and local probes the d-metal alloy Ni_{1-x}V_{x} close to the quantum critical concentration, x_{c}≈11.6%, where the ferromagnetic transition temperature vanishes. The magnetization-field curve in the ferromagnetic phase takes an anomalous power-law form with a nonuniversal exponent that is strongly x dependent and mirrors the behavior in the paramagnetic phase. Muon spin rotation experiments demonstrate inhomogeneous magnetic order and indicate the presence of dynamic fluctuating magnetic clusters...
June 30, 2017: Physical Review Letters
https://www.readbyqxmd.com/read/28705989/emergent-cellular-self-organization-and-mechanosensation-initiate-follicle-pattern-in-the-avian-skin
#15
Amy E Shyer, Alan R Rodrigues, Grant G Schroeder, Elena Kassianidou, Sanjay Kumar, Richard M Harland
The spacing of hair in mammals and feathers in birds is one of the most apparent morphological features of the skin. This pattern arises when uniform fields of progenitor cells diversify their molecular fate while adopting higher-order structure. Using the nascent skin of the developing chicken embryo as a model system, we find that morphological and molecular symmetries are simultaneously broken by an emergent process of cellular self-organization. The key initiators of heterogeneity are dermal progenitors, which spontaneously aggregate through contractility-driven cellular pulling...
July 13, 2017: Science
https://www.readbyqxmd.com/read/28704262/effect-of-upper-body-position-on-arterial-stiffness-influence-of-hydrostatic-pressure-and-autonomic-function
#16
Elizabeth C Schroeder, Alexander J Rosenberg, Thessa I M Hilgenkamp, Daniel W White, Tracy Baynard, Bo Fernhall
OBJECTIVE: To evaluate changes in arterial stiffness with positional change and whether the stiffness changes are due to hydrostatic pressure alone or if physiological changes in vasoconstriction of the conduit arteries play a role in the modulation of arterial stiffness. METHODS: Thirty participants' (male = 15, 24 ± 4 years) upper bodies were positioned at 0, 45, and 72° angles. Pulse wave velocity (PWV), cardio-ankle vascular index, carotid beta-stiffness index, carotid blood pressure (cBP), and carotid diameters were measured at each position...
July 12, 2017: Journal of Hypertension
https://www.readbyqxmd.com/read/28701211/inpatient-rehabilitation-for-adult-patients-with-marfan-syndrome-an-observational-pilot-study
#17
Dieter Benninghoven, Denise Hamann, Yskert von Kodolitsch, Meike Rybczynski, Julia Lechinger, Friedrich Schroeder, Marina Vogler, Eike Hoberg
BACKGROUND: Advances in medical, interventional and surgical treatment have increased average life expectancy of patients with congenital heart defects. As a result a new group of adult patients with congenital cardiac defects requires medical rehabilitation. Patients with Marfan syndrome (MFS) are a relevant group among these patients. So far, no reports on the effectiveness of specialized rehabilitation programmes for MFS patients exist. We implemented an inpatient 3-week rehabilitation program for MFS patients at the Muehlenberg-Clinic for rehabilitation and assessed the medical safety as well as the impact of the program on physical fitness and psychological wellbeing of participants by means of an observational pilot study...
July 12, 2017: Orphanet Journal of Rare Diseases
https://www.readbyqxmd.com/read/28698349/a-pilot-randomised-controlled-trial-of-a-periodised-resistance-training-and-protein-supplementation-intervention-in-prostate-cancer-survivors-on-androgen-deprivation-therapy
#18
Jacqueline L Kiwata, Tanya B Dorff, E Todd Schroeder, George J Salem, Christianne J Lane, Judd C Rice, Mitchell E Gross, Christina M Dieli-Conwright
INTRODUCTION: Prostate cancer survivors (PCS) receiving androgen deprivation therapy (ADT) experience deleterious side effects such as unfavourable changes in cardiometabolic factors that lead to sarcopenic obesity and metabolic syndrome (MetS). While loss of lean body mass (LBM) compromises muscular strength and quality of life, MetS increases the risk of cardiovascular disease and may influence cancer recurrence. Exercise can improve LBM and strength, and may serve as an alternative to the pharmacological management of MetS in PCS on ADT...
July 10, 2017: BMJ Open
https://www.readbyqxmd.com/read/28698284/breaching-peripheral-tolerance-promotes-the-production-of-hiv-1-neutralizing-antibodies
#19
Kristin M S Schroeder, Amanda Agazio, Pamela J Strauch, Sean T Jones, Scott B Thompson, Michael S Harper, Roberta Pelanda, Mario L Santiago, Raul M Torres
A subset of characterized HIV-1 broadly neutralizing antibodies (bnAbs) are polyreactive with additional specificities for self-antigens and it has been proposed immunological tolerance may present a barrier to their participation in protective humoral immunity. We address this hypothesis by immunizing autoimmune-prone mice with HIV-1 Envelope (Env) and characterizing the primary antibody response for HIV-1 neutralization. We find autoimmune mice generate neutralizing antibody responses to tier 2 HIV-1 strains with alum treatment alone in the absence of Env...
July 11, 2017: Journal of Experimental Medicine
https://www.readbyqxmd.com/read/28695878/impact-of-biliopancreatic-limb-length-on-severe-protein%C3%A2-calorie-malnutrition-requiring-revisional-surgery-after-one-anastomosis-mini-gastric-bypass
#20
Kamal Kumar Mahawar, Chetan Parmar, William R J Carr, Neil Jennings, Norbert Schroeder, Peter K Small
BACKGROUND: One anastomosis (mini) gastric bypass (OAGB) is believed to be more malabsorptive than Roux-en-Y gastric bypass. A number of patients undergoing this procedure suffer from severe protein‒calorie malnutrition requiring revisional surgery. The purpose of this study was to find the magnitude of severe protein‒calorie malnutrition requiring revisional surgery after OAGB and any potential relationship with biliopancreatic limb (BPL) length. METHODS: A questionnaire-based survey was carried out on the surgeons performing OAGB...
July 7, 2017: Journal of Minimal Access Surgery
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