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https://www.readbyqxmd.com/read/28099652/path-of-infectious-diseases-in-brazil-in-the-last-50-years-an-ongoing-challenge
#1
Eliseu Alves Waldman, Ana Paula Sayuri Sato
In this article, we comment on the main features of infectious diseases in Brazil in the last 50 years, highlighting how much of this path Revista de Saúde Pública could portray. From 1967 to 2016, 1,335 articles focusing on infectious diseases were published in Revista de Saúde Pública. Although the proportion of articles on the topic have decreased from about 50.0% to 15.0%, its notability remained and reflected the growing complexity of the research required for its control. It is noteworthy that studies design and analysis strategies progressively became more sophisticated, following the great development of epidemiology in Brazil in the recent decades...
December 22, 2016: Revista de Saúde Pública
https://www.readbyqxmd.com/read/28097318/emerging-and-reemerging-infectious-diseases-the-dichotomy-between-acute-outbreaks-and-chronic-endemicity
#2
Catharine I Paules, Anthony S Fauci
No abstract text is available yet for this article.
January 12, 2017: JAMA: the Journal of the American Medical Association
https://www.readbyqxmd.com/read/28095455/novel-porcine-epidemic-diarrhea-virus-pedv-variants-with-large-deletions-in-the-spike-s-gene-coexist-with-pedv-strains-possessing-an-intact-s-gene-in-domestic-pigs-in-japan-a-new-disease-situation
#3
Nguyen Van Diep, Junzo Norimine, Masuo Sueyoshi, Nguyen Thi Lan, Ryoji Yamaguchi
Since late 2013, after an absence of seven years, outbreaks of porcine epidemic diarrhea virus (PEDV) infection have reemerged and swept rapidly across Japan, resulting in significant economic losses. In this study, we report the emergence, mixed infection, and genetic characterization of 15 novel field PEDV variants with large genomic deletions. The sizes of deletion varied between 582 nt (194 aa) and 648 nt (216 aa) at positions 28-714 (10-238) on the S gene (protein). Among 17 PEDV samples isolated from individual pigs, all of them contained at least two distinct genotypes with large genomic deletions, and 94...
2017: PloS One
https://www.readbyqxmd.com/read/28092259/-first-case-of-chikungunya-fever-in-hermosillo-sonora-mexico
#4
Miguel Ángel Martínez-Medina, Ismael Antonio Cañedo-Dorame
The Chikungunya is an arbovirus first described during a 1952 outbreak of febrile exantematic disease in southern Tanganyika (now Tanzania). It is a virus within the alphavirus genus of the Togaviridae family, it is usually transmitted to humans by Aedes mosquitoes. Typically, the disease manifests as acute onset of fever and joint pains. This study describes the clinical characteristics the first imported case infected with chikungunya fever (CHIK) in Hermosillo, Sonora, Mexico. We report the case of a 30 years old man seen in our emergency department due to fever, polyarthralgia, rash and headache...
January 2017: Revista Médica del Instituto Mexicano del Seguro Social
https://www.readbyqxmd.com/read/28076445/emerging-bordetella-pertussis-strains-induce-enhanced-signaling-of-human-pattern-recognition-receptors-tlr2-nod2-and-secretion-of-il-10-by-dendritic-cells
#5
Elise S Hovingh, Marjolein van Gent, Hendrik-Jan Hamstra, Marc Demkes, Frits R Mooi, Elena Pinelli
Vaccines against pertussis have been available for more than 60 years. Nonetheless, this highly contagious disease is reemerging even in countries with high vaccination coverage. Genetic changes of Bordetella pertussis over time have been suggested to contribute to the resurgence of pertussis, as these changes may favor escape from vaccine-induced immunity. Nonetheless, studies on the effects of these bacterial changes on the immune response are limited. Here, we characterize innate immune recognition and activation by a collection of genetically diverse B...
2017: PloS One
https://www.readbyqxmd.com/read/28004307/the-potential-of-social-media-and-internet-based-data-in-preventing-and-fighting-infectious-diseases-from-internet-to-twitter
#6
Khaled Al-Surimi, Mohammed Khalifa, Salwa Bahkali, Ashraf El-Metwally, Mowafa Househ
Health threats due to infectious diseases used to be a major public health concerns around the globe till mid of twentieth century when effective public health interventions helped in eradicating a number of infectious diseases around the world. Over the past 15 years, there has been a rise in the number of emerging and reemerging infectious diseases being reported such as the Acute Respiratory Syndrome (SARS) in 2002, HINI in 2009, Middle East Respiratory Syndrome (MERS) in 2012, Ebola in 2014, and Zika in 2016...
December 22, 2016: Advances in Experimental Medicine and Biology
https://www.readbyqxmd.com/read/27983501/a-framework-for-modeling-emerging-diseases-to-inform-management
#7
Robin E Russell, Rachel A Katz, Katherine L D Richgels, Daniel P Walsh, Evan H C Grant
The rapid emergence and reemergence of zoonotic diseases requires the ability to rapidly evaluate and implement optimal management decisions. Actions to control or mitigate the effects of emerging pathogens are commonly delayed because of uncertainty in the estimates and the predicted outcomes of the control tactics. The development of models that describe the best-known information regarding the disease system at the early stages of disease emergence is an essential step for optimal decision-making. Models can predict the potential effects of the pathogen, provide guidance for assessing the likelihood of success of different proposed management actions, quantify the uncertainty surrounding the choice of the optimal decision, and highlight critical areas for immediate research...
January 2017: Emerging Infectious Diseases
https://www.readbyqxmd.com/read/27880753/notes-from-the-field-community-based-prevention-of-rocky-mountain-spotted-fever-sonora-mexico-2016
#8
Anne Straily, Naomi Drexler, Denica Cruz-Loustaunau, Christopher D Paddock, Gerardo Alvarez-Hernandez
Rocky Mountain spotted fever (RMSF), a life-threatening tickborne zoonosis caused by Rickettsia rickettsii, is a reemerging disease in Mexico (1,2). R. rickettsii is an intracellular bacterium that infects vascular endothelium and can cause multisystem organ failure and death in the absence of timely administration of a tetracycline-class antibiotic, typically doxycycline. Epidemic RMSF, as described in parts of Arizona and Mexico, is associated with massive local infestations of the brown dog tick (Rhiphicephalus sanguineus sensu lato) on domestic dogs and in peridomestic settings that result in high rates of human exposure; for example, during 2003-2012, in Arizona the incidence of RMSF in the three most highly affected communities was 150 times the U...
November 25, 2016: MMWR. Morbidity and Mortality Weekly Report
https://www.readbyqxmd.com/read/27869387/-trends-in-pertussis-mortality-and-morbidity-in-colombia-2002-2012
#9
Doris Cardona, María Osley Garzón, Mateo Calle, Maite Catalina Agudelo, Ángela Segura
Whooping cough is a public health problem that mainly affects children under one year of age with highly lethal outcomes. It is a re-emerging disease, which is preventable by immunization. Objective: To analyze mortality and morbidity trends of whooping cough in Colombia between 2002 and 2012. Materials and methods: We conducted a quantitative descriptive study of deaths by pertussis between 2002 and 2012 using data from death certificates registered by the Departamento Administrativo Nacional de Estadística, and cases reported to the Sistema Nacional de Vigilancia en Salud Pública, 2005-2012...
September 1, 2016: Biomédica: Revista del Instituto Nacional de Salud
https://www.readbyqxmd.com/read/27720044/temperature-dependent-effects-on-the-replication-and-transmission-of-arthropod-borne-viruses-in-their-insect-hosts
#10
Glady Hazitha Samuel, Zach N Adelman, Kevin M Myles
The transmissibility of vector borne viruses can be affected by a combination of factors, both extrinsic (climatic changes, temperature, urbanization, among others) and intrinsic (genetics, life span, immunity, among others). Temperature is of particular importance since the insect vectors of arthropod-borne viruses (arboviruses) are ectothermic and acutely susceptible to temperature changes. Modeling suggests that with increasing global temperature and urbanization, arboviral diseases will continue to emerge or reemerge...
August 2016: Current Opinion in Insect Science
https://www.readbyqxmd.com/read/27598706/cdc-s-flexible-epidemiologist-a-strategy-for-enhancing-health-department-infectious-disease-epidemiology-capacity
#11
Christina Chung, Leah S Fischer, Angelica OʼConnor, Alvin Shultz
CONTEXT: CDC's Epidemiology and Laboratory Capacity for Infectious Diseases (ELC) Cooperative Agreement aims to help health departments strengthen core epidemiology capacity needed to respond to a variety of emerging infectious diseases. In fiscal year 2014, $6 million was awarded to 41 health departments for flexible epidemiologists (FEs). FEs were intended to help meet health departments' unique needs and support unanticipated events that could require the diversion of resources to specific emerging or reemerging diseases...
September 2, 2016: Journal of Public Health Management and Practice: JPHMP
https://www.readbyqxmd.com/read/27324390/exosomes-in-viral-disease
#12
REVIEW
Monique R Anderson, Fatah Kashanchi, Steven Jacobson
Viruses have evolved many mechanisms by which to evade and subvert the immune system to ensure survival and persistence. However, for each method undertaken by the immune system for pathogen removal, there is a counteracting mechanism utilized by pathogens. The new and emerging role of microvesicles in immune intercellular communication and function is no different. Viruses across many different families have evolved to insert viral components in exosomes, a subtype of microvesicle, with many varying downstream effects...
July 2016: Neurotherapeutics: the Journal of the American Society for Experimental NeuroTherapeutics
https://www.readbyqxmd.com/read/27284221/loop-mediated-isothermal-amplification-an-innovative-gene-amplification-technique-for-animal-diseases
#13
REVIEW
Pravas Ranjan Sahoo, Kamadev Sethy, Swagat Mohapatra, Debasis Panda
India being a developing country mainly depends on livestock sector for its economy. However, nowadays, there is emergence and reemergence of more transboundary animal diseases. The existing diagnostic techniques are not so quick and with less specificity. To reduce the economy loss, there should be a development of rapid, reliable, robust diagnostic technique, which can work with high degree of sensitivity and specificity. Loop mediated isothermal amplification assay is a rapid gene amplification technique that amplifies nucleic acid under an isothermal condition with a set of designed primers spanning eight distinct sequences of the target...
May 2016: Veterinary World
https://www.readbyqxmd.com/read/27242902/liposomal-systems-as-nanocarriers-for-the-antiviral-agent-ivermectin
#14
Romina Croci, Elisabetta Bottaro, Kitti Wing Ki Chan, Satoru Watanabe, Margherita Pezzullo, Eloise Mastrangelo, Claudio Nastruzzi
RNA virus infections can lead to the onset of severe diseases such as fever with haemorrhage, multiorgan failure, and mortality. The emergence and reemergence of RNA viruses continue to pose a significant public health threat worldwide with particular attention to the increasing incidence of flaviviruses, among others Dengue, West Nile Virus, and Yellow Fever viruses. Development of new and potent antivirals is thus urgently needed. Ivermectin, an already known antihelminthic drug, has shown potent effects in vitro on Flavivirus helicase, with EC50 values in the subnanomolar range for Yellow Fever and submicromolar EC50 for Dengue Fever, Japanese encephalitis, and tick-borne encephalitis viruses...
2016: International Journal of Biomaterials
https://www.readbyqxmd.com/read/27216777/genomic-analysis-of-the-emergence-evolution-and-spread-of-human-respiratory-rna-viruses
#15
Tommy T-Y Lam, Huachen Zhu, Yi Guan, Edward C Holmes
The emergence and reemergence of rapidly evolving RNA viruses-particularly those responsible for respiratory diseases, such as influenza viruses and coronaviruses-pose a significant threat to global health, including the potential of major pandemics. Importantly, recent advances in high-throughput genome sequencing enable researchers to reveal the genomic diversity of these viral pathogens at much lower cost and with much greater precision than they could before. In particular, the genome sequence data generated allow inferences to be made on the molecular basis of viral emergence, evolution, and spread in human populations in real time...
August 31, 2016: Annual Review of Genomics and Human Genetics
https://www.readbyqxmd.com/read/27191223/reemergence-of-dengue-in-southern-texas-2013
#16
Dana L Thomas, Gilberto A Santiago, Roman Abeyta, Steven Hinojosa, Brenda Torres-Velasquez, Jessica K Adam, Nicole Evert, Elba Caraballo, Elizabeth Hunsperger, Jorge L Muñoz-Jordán, Brian Smith, Alison Banicki, Kay M Tomashek, Linda Gaul, Tyler M Sharp
During a dengue epidemic in northern Mexico, enhanced surveillance identified 53 laboratory-positive cases in southern Texas; 26 (49%) patients acquired the infection locally, and 29 (55%) were hospitalized. Of 83 patient specimens that were initially IgM negative according to ELISA performed at a commercial laboratory, 14 (17%) were dengue virus positive by real-time reverse transcription PCR performed at the Centers for Disease Control and Prevention. Dengue virus types 1 and 3 were identified, and molecular phylogenetic analysis demonstrated close identity with viruses that had recently circulated in Mexico and Central America...
June 2016: Emerging Infectious Diseases
https://www.readbyqxmd.com/read/27139445/visceral-leishmaniasis-in-benishangul-gumuz-regional-state-western-ethiopia-reemerging-or-emerging
#17
Adugna Abera, Geremew Tasew, Teshome Tsegaw, Asfaw Kejella, Abate Mulugeta, Dagimlidet Worku, Abraham Aseffa, Endalamaw Gadisa
Kala-azar is a growing public health problem in Ethiopia. Benishangul-Gumuz regional state was previously not known to be endemic for the disease. In response to a case report from the region, we conducted a rapid assessment survey. A pretested questionnaire was used to capture sociodemographic and clinical histories pertinent to kala-azar. Study participants with complaints of fever and headache for 2 weeks or more were tested for kala-azar and malaria. All participants were screened with the leishmanin skin test and the direct agglutination test for exposure to Leishmania, defined as a positive result with either or both tests...
July 6, 2016: American Journal of Tropical Medicine and Hygiene
https://www.readbyqxmd.com/read/27106280/daily-zero-reporting-for-suspect-ebola-using-short-message-service-sms-in-guinea-bissau
#18
V M Cáceres, P Cardoso, S Sidibe, S Lambert, A Lopez, B Pedalino, D J Herrera Guibert
OBJECTIVE: Intensified surveillance will be vital in the elimination phase to verify Ebola-free status and mitigate potential reemergence of the disease in West Africa. Zero-reporting from high-risk districts is a key strategy for surveillance. Our objective was to implement a pilot investigation to assess the feasibility of using short message service (SMS) texting for daily reporting of Ebola cases under investigation (CUI) in Guinea-Bissau in the context of an ongoing emergency-response training program known as Surveillance Training for Ebola Preparedness (STEP)...
September 2016: Public Health
https://www.readbyqxmd.com/read/27089119/an-operational-framework-for-insecticide-resistance-management-planning
#19
LETTER
Emmanuel Chanda, Edward K Thomsen, Mulenga Musapa, Mulakwa Kamuliwo, William G Brogdon, Douglas E Norris, Freddie Masaninga, Robert Wirtz, Chadwick H Sikaala, Mbanga Muleba, Allen Craig, John M Govere, Hilary Ranson, Janet Hemingway, Aklilu Seyoum, Michael B Macdonald, Michael Coleman
Arthropod vectors transmit organisms that cause many emerging and reemerging diseases, and their control is reliant mainly on the use of chemical insecticides. Only a few classes of insecticides are available for public health use, and the increased spread of insecticide resistance is a major threat to sustainable disease control. The primary strategy for mitigating the detrimental effects of insecticide resistance is the development of an insecticide resistance management plan. However, few examples exist to show how to implement such plans programmatically...
May 2016: Emerging Infectious Diseases
https://www.readbyqxmd.com/read/27047211/epidemiological-surveillance-of-capybaras-and-ticks-on-warning-area-for-brazilian-spotted-fever
#20
José Brites-Neto, Jardel Brasil, Keila Maria Roncato Duarte
AIM: The vulnerability of tropical developing countries to the emerging disease constitutes a critical phenomenon in which the invasion of wild niches by human hosts, contributes to expansion of zoonotic diseases, such as the Brazilian spotted fever (BSF). This study performed a diagnosis of species occurrence of their hosts (Hydrochoerus hydrochaeris) and vectors (Amblyomma sculptum and Amblyomma dubitatum) on the warning area for this reemerging disease in Brazil. MATERIALS AND METHODS: The study was conducted in a warning area for BSF in the city of Americana, São Paulo state...
September 2015: Veterinary World
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