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Mixed depression

Rachel K Peterson, Jason M Ashford, Sarah M Scott, Fang Wang, Hui Zhang, Julie A Bradley, Thomas E Merchant, Heather M Conklin
BACKGROUND: Childhood brain tumor diagnoses are stressful for families. Children diagnosed with craniopharyngioma (Cp) present with particularly challenging medical and cognitive problems due to tumor location and associated biophysiologic comorbidities. This study examined parental distress in a sample of families of patients with Cp treated with proton beam therapy to identify factors for targeting psychological intervention. PROCEDURE: Prior to (n = 96) and 1 year after (n = 73) proton therapy, parents of children diagnosed with Cp (9...
June 22, 2018: Pediatric Blood & Cancer
Marnina Swartz-Vanetik, Mark Zeevin, Yoram Barak
BACKGROUND: Suicide is often associated with depression in patients suffering from bipolar disorder (BD) and less is known about its relation to mania. Available data suggest that patients in the manic phase of BD may be at risk of suicide. AIM: We characterized suicide attempts in a cohort of patients with BD in manic and mixed phases. METHOD: We focused on the scope, rate, and characteristics of suicide attempts among BD patients during manic or mixed states...
June 21, 2018: Crisis
Man Guo, Meredith Stensland, Mengting Li, Xinqi Dong, Agnes Tiwari
Background and Objectives: The migrating age of an individual has far-reaching implications for their acculturation experience, social integration, and well-being. This study addressed two questions: Is migrating at older age associated with poorer psychological well-being? If so, what factors account for such differences? Research Design and Methods: Using data of 3,138 Chinese elderly people in Chicago, we compared the levels of depression and quality of life among individuals who migrated in young adulthood (before 35), adulthood (35-49), midlife (50-64), and later life (65+)...
June 20, 2018: Gerontologist
J M Oliver-Baxter, H S Whitford, D A Turnbull, M J Bond
BACKGROUND: Multivitamins are a popular supplement taken to promote physical and mental health. During periods of stress, they may have a protective role for health and wellbeing, although the current evidence of their efficacy is mixed. OBJECTIVE: To determine whether multivitamin supplementation impacts psychological and inflammatory markers of women who are experiencing psychological distress. DESIGN, SETTING, PARTICIPANTS AND INTERVENTIONS: An 8-week randomized controlled trial was conducted to assess changes in both psychological state and pro-inflammatory markers of patients receiving multivitamins or placebo...
June 7, 2018: Journal of Integrative Medicine
Freek Ten Doesschate, Guido A van Wingen, Boudewijn J H B de Pont, Martijn Arns, Jeroen A van Waarde
OBJECTIVES: Electroconvulsive therapy (ECT) is an effective treatment for severe depression. Electroencephalogram (EEG) measures between ECT sessions seem to be related to the antidepressant efficacy of ECT. In this naturalistic cohort study, we examine longitudinal effects of ECT on interhemispheric EEG coherence measures during seizure activity and its relation to the antidepressant efficacy. METHODS: This study included 65 patients diagnosed with severe depressive disorder...
June 1, 2018: Clinical EEG and Neuroscience: Official Journal of the EEG and Clinical Neuroscience Society (ENCS)
Verinder Sharma
INTRODUCTION: The development of mania during weaning is an underreported phenomenon that has received little attention in the recent past. Lack of timely diagnosis and effective management can negatively affect not only the mother but also her family. Main issue: I describe the case of a woman who experienced onset of mixed mania during weaning. At that time, she was diagnosed with bipolar I disorder, current episode manic, and a mixed-features specifier. The woman had a history of bipolar II disorder and a family history of postpartum depression and bipolar disorder...
June 1, 2018: Journal of Human Lactation: Official Journal of International Lactation Consultant Association
Ricardo Brandt, Guilherme G Bevilacqua, Danilo R Coimbra, Luiz C Pombo, Bianca Miarka, Andrew M Lane
Brandt, R, Bevilacqua, GG, Coimbra, DR, Pombo, LC, Miarka, B, and Lane, AM. Body weight and mood state modifications in mixed martial arts: An exploratory pilot. J Strength Cond Res XX(X): 000-000, 2018-Mixed martial arts (MMA) fighters typically use rapid weight loss (RWL) as a strategy to make competition weight. The aim of the present study was to compare body weight and mood changes in professional male MMA athletes who used strategies to rapidly lose weight (n = 9) and with MMA athletes who did not (n = 3)...
June 20, 2018: Journal of Strength and Conditioning Research
Martin Härter, Birgit Watzke, Anne Daubmann, Karl Wegscheider, Hans-Helmut König, Christian Brettschneider, Sarah Liebherz, Daniela Heddaeus, Maya Steinmann
Guidelines recommend stepped and collaborative care models (SCM) for depression. We aimed to evaluate the effectiveness of a complex guideline-based SCM for depressed patients. German primary care units were cluster-randomised into intervention (IG) or control group (CG) (3:1 ratio). Adult routine care patients with PHQ-9 ≥ 5 points could participate and received SCM in IG and treatment as usual (TAU) in CG. Primary outcome was change in PHQ-9 from baseline to 12 months (hypothesis: greater reduction in IG)...
June 20, 2018: Scientific Reports
Sherry Pagoto, Bengisu Tulu, Emmanuel Agu, Molly E Waring, Jessica L Oleski, Danielle E Jake-Schoffman
BACKGROUND: Reviews of weight loss mobile apps have revealed they include very few evidence-based features, relying mostly on self-monitoring. Unfortunately, adherence to self-monitoring is often low, especially among patients with motivational challenges. One behavioral strategy that is leveraged in virtually every visit of behavioral weight loss interventions and is specifically used to deal with adherence and motivational issues is problem solving. Problem solving has been successfully implemented in depression mobile apps, but not yet in weight loss apps...
June 20, 2018: JMIR MHealth and UHealth
Marco Solmi, Cristiano A Köhler, Brendon Stubbs, Ai Koyanagi, Beatrice Bortolato, Francesco Monaco, Davy Vancampfort, Myrela O Machado, Michael Maes, Ioanna Tzoulaki, Joseph Firth, John P A Ioannidis, André F Carvalho
BACKGROUND: Multiple environmental factors have been implicated in obesity and multiple interventions, besides drugs and surgery, have been assessed in obese patients. Results are scattered across many studies and meta-analyses and they often mix obese and overweight individuals. MATERIALS AND METHODS: PubMed and Cochrane Database of Systematic Reviews were searched through January 21st , 2017 for meta-analyses of cohort studies assessing environmental risk factors for obesity, and randomized controlled trials investigating non-pharmacological, non-surgical therapeutic interventions for obesity...
June 20, 2018: European Journal of Clinical Investigation
Rose M Collard, Sanne Wassink-Vossen, Aart H Schene, Paul Naarding, Peter Verhaak, Richard C Oude Voshaar, Hannie C Comijs
OBJECTIVES: Functional limitations give an indication of the total impact of diseases, such as depression, on individuals health and recovery. This study examines the change in several domains of functioning over 2 years in older persons depressed at baseline (non-remitted group and remitted group after 2 years) and in a non-depressed comparison group. METHODS: Data were used from a cohort study (Netherlands Study of Depression in Older persons [NESDO]) consisting of depressed older persons ≥ 60 years (N = 378) and a non-depressed comparison group (N = 132) with 2 years of follow-up (attrition rate 24%)...
June 19, 2018: Social Psychiatry and Psychiatric Epidemiology
Fabrice Jollant, Gerd Wagner, Stéphane Richard-Devantoy, Stefanie Köhler, Karl-Jürgen Bär, Gustavo Turecki, Fabricio Pereira
The identification of brain markers of suicidal risk is highly expected. However, neuroimaging studies have yielded mixed results, possibly due to phenotypic heterogeneity. In the present study, we addressed this issue using structural brain imaging. First, two independent samples of suicide attempters (n = 17 in Montreal, 32 in Jena), patient controls (n = 26/34), and healthy controls (n = 66/34) were scanned with magnetic resonance imaging. Groups were compared with FSL. We then reviewed the literature and run a GingerALE meta-analysis of 12 structural imaging studies comparing suicide attempters and patient controls with whole-brain analyses (n = 693)...
June 19, 2018: Translational Psychiatry
Steven Pham, Giovanna Porta, Candice Biernesser, Monica Walker Payne, Satish Iyengar, Nadine Melhem, David A Brent
OBJECTIVE: The authors sought to determine the long-term impact of sudden parental death on youths and pathways between youth bereavement and impairment. METHODS: Youths (N=216) who lost a parent to suicide, accident, or sudden natural death and nonbereaved youths (N=172) were followed periodically for up to 7 years. The incidence and prevalence of disorder and of functional impairment, as well as pathways to impairment, were assessed using Cox and mixed-effects logistic regression and structural equation modeling...
June 20, 2018: American Journal of Psychiatry
Jill E Bormann, Steven R Thorp, Eric Smith, Mark Glickman, Danielle Beck, Dorothy Plumb, Shibei Zhao, Princess E Ackland, Carie S Rodgers, Pia Heppner, Lawrence R Herz, A Rani Elwy
OBJECTIVE: Previous studies suggest that group "mantram" (sacred word) repetition therapy, a non-trauma-focused complementary therapy for posttraumatic stress disorder (PTSD), may be an effective treatment for veterans. The authors compared individually delivered mantram repetition therapy and another non-trauma-focused treatment for PTSD. METHOD: The study was a two-site, open-allocation, blinded-assessment randomized trial involving 173 veterans diagnosed with military-related PTSD from two Veterans Affairs outpatient clinics (January 2012 to March 2014)...
June 20, 2018: American Journal of Psychiatry
H F Dorland, F I Abma, C A M Roelen, R Stewart, B C Amick, U Bültmann, A V Ranchor
OBJECTIVE: Cancer patients can experience work-specific cognitive symptoms post return to work (RTW). The study aims to: 1) describe the course of work-specific cognitive symptoms in the first 18 months post RTW, and 2) examine the associations of work characteristics, fatigue and depressive symptoms with work-specific cognitive symptoms over time. METHODS: This study used data from the 18-months longitudinal "Work Life after Cancer" cohort. The Cognitive Symptom Checklist-Work, Dutch Version (CSC-W DV) was used to measure work-specific cognitive symptoms...
June 19, 2018: Psycho-oncology
Leila Niemi-Murola, Jani Unkuri, Katri Hamunen
Introduction and aim Pain is a frequent symptom in emergency patients and opioids are commonly used to treat it at emergency departments and at pre-hospital settings. The aim of this systematic review is to examine the efficacy and safety of parenteral opioids used for acute pain in emergency medicine. Method Qualitative review of randomized controlled trials (RCTs) on parenteral opioids for acute pain in adult emergency patients. Main outcome measures were: type and dose of the opioid, analgesic efficacy as compared to either placebo or another opioid and adverse effects...
December 29, 2017: Scandinavian Journal of Pain
Lorraine J Phillips, Nancy M Birtley, Gregory F Petroski, Carol Siem, Marilyn Rantz
INTRODUCTION: Antipsychotic use in nursing homes varies widely across the United States; inadequate staffing, skill mix, and geropsychiatric training impede sustained improvement. AIM: This study identified risk factors of antipsychotic use in long-stay residents lacking qualifying or potentially qualifying diagnoses. METHOD: This secondary analysis used 2015 Minimum Data Set and cost report data from 458 Missouri nursing homes. The full sample (N=29,679) was split into two subsamples: residents with (N=15,114) and without (N=14,565) a dementia diagnosis...
June 17, 2018: Journal of Psychiatric and Mental Health Nursing
Hans W Jeuring, Max L Stek, Martijn Huisman, Richard C Oude Voshaar, Paul Naarding, Rose M Collard, Roos C van der Mast, Rob M Kok, Aartjan T F Beekman, Hannie C Comijs
OBJECTIVES: To examine the six-year prognosis of patients with late-life depression and to identify prognostic factors of an unfavorable course. DESIGN AND SETTING: The Netherlands Study of Depression in Older Persons (NESDO) is a multisite naturalistic prospective cohort study with six-year follow-up. PARTICIPANTS: Three hundred seventy-eight clinically depressed patients (according to Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition Text Revision criteria) and 132 nondepressed comparisons were included at baseline between 2007 and 2010...
May 17, 2018: American Journal of Geriatric Psychiatry
Eric J Brunner, Martin J Shipley, Sara Ahmadi-Abhari, Carlos Valencia Hernandez, Jessica G Abell, Archana Singh-Manoux, Ichiro Kawachi, Mika Kivimaki
BACKGROUND: Health inequalities persist into old age. We aimed to investigate risk factors for socioeconomic differences in frailty that could potentially be modified through policy measures. METHODS: In this multi-wave longitudinal cohort study (Whitehall II study), we assessed participants' socioeconomic status, behavioural and biomedical risk factors, and disease status at age 45-55 years, and frailty (defined according to the Fried phenotype) at baseline and at one or more of three clinic visits about 18 years later (mean age 69 years [SD 5·9])...
June 13, 2018: Lancet. Public Health
Betty-Shannon Prevatt, Evan M Lowder, Sarah L Desmarais
OBJECTIVE: Postpartum mood disorders represent a serious problem affecting 10-20% of women and support groups offer a promising intervention modality. The current study examined participant satisfaction with and effectiveness of a peer-facilitated postpartum support group. INTERVENTION: The program consists of a free, peer-support group, developed to increase social support and destigmatise postpartum mood symptoms. The weekly group is co-facilitated by former group attendees and maternal health professionals...
May 31, 2018: Midwifery
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