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https://www.readbyqxmd.com/read/29655977/dexmedetomidine-or-fentanyl-cardiovascular-stability-and-analgesia-during-propofol-ketamine-total-intravenous-anaesthesia-in-experimental-pigs
#1
Andreas Lervik, Joanna Raszplewicz, Birgit Ranheim, Susanna Solbak, Simen F Toverud, Henning A Haga
OBJECTIVE: To compare cardiovascular function and response to nociception during total intravenous anaesthesia in pigs with propofol, ketamine and either dexmedetomidine or fentanyl administered as a continuous infusion. STUDY DESIGN: Blinded, randomized, balanced, crossover study ANIMALS: Eight immunocastrated male, mixed breed pigs with a mean ± standard deviation body weight of 26.4 ± 1.9 kg for dexmedetomidine and 27.5 ± 3.8 kg for fentanyl treatment...
December 5, 2017: Veterinary Anaesthesia and Analgesia
https://www.readbyqxmd.com/read/29655654/factorial-structure-and-familial-aggregation-of-the-hypomania-checklist-32-hcl-32-results-of-the-nimh-family-study-of-affective-spectrum-disorders
#2
Jennifer Glaus, Anna Van Meter, Lihong Cui, Ciro Marangoni, Kathleen R Merikangas
BACKGROUND: There is substantial evidence that bipolar disorder (BD) manifests on a spectrum rather than as a categorical condition. Detection of people with subthreshold manifestations of BD is therefore important. The Hypomania Checklist-32 (HCL-32) was developed as a tool to identify such people. PURPOSE: The aims of this paper were to: (1) investigate the factor structure of HCL-32; (2) determine whether the HCL-32 can discriminate between mood disorder subtypes; and (3) assess the familial aggregation and cross-aggregation of hypomanic symptoms assessed on the HCL with BD...
April 3, 2018: Comprehensive Psychiatry
https://www.readbyqxmd.com/read/29655640/how-are-ocular-signs-and-symptoms-of-dry-eye-associated-with-depression-in-women-with-and-without-sj%C3%A3-gren-s-syndrome
#3
John A Gonzales, Annie Chou, Jennifer R Rose-Nussbaumer, Vatinee Y Bunya, Lindsey A Criswell, Caroline H Shiboski, Thomas M Lietman
PURPOSE: To determine whether ocular phenotypic features of keratoconjunctivitis sicca (KCS) and/or participant-reported symptoms of dry eye disease are associated with depression in women participants enrolled in the Sjögren's International Collaborative Clinical Alliance (SICCA). DESIGN: Cross-sectional study. METHODS: Women enrolled in the SICCA registry from 9 international research sites. Participants met at least one of five inclusion criteria for registry enrollment (including complaints of dry eyes or dry mouth, a previous diagnosis of Sjögren's syndrome (SS), abnormal serology (positive anti-Sjögren's syndrome-related antigen A and/or B (anti-SSA and/or anti-SSB), or elevated anti-nuclear antibody and rheumatoid factor), bilateral parotid gland enlargement, or multiple dental caries)...
April 12, 2018: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/29655586/non-motor-outcomes-of-subthalamic-stimulation-in-parkinson-s-disease-depend-on-location-of-active-contacts
#4
Haidar Salimi Dafsari, Jan Niklas Petry-Schmelzer, K Ray-Chaudhuri, Keyoumars Ashkan, Luca Weis, Till A Dembek, Michael Samuel, Alexandra Rizos, Monty Silverdale, Michael T Barbe, Gereon R Fink, Julian Evans, Pablo Martinez-Martin, Angelo Antonini, Veerle Visser-Vandewalle, Lars Timmermann
BACKGROUND: Subthalamic nucleus (STN) deep brain stimulation (DBS) improves quality of life (QoL), motor, and non-motor symptoms (NMS) in Parkinson's disease (PD). Few studies have investigated the influence of the location of neurostimulation on NMS. OBJECTIVE: To investigate the impact of active contact location on NMS in STN-DBS in PD. METHODS: In this prospective, open-label, multicenter study including 50 PD patients undergoing bilateral STN-DBS, we collected NMSScale (NMSS), NMSQuestionnaire (NMSQ), Hospital Anxiety and Depression Scale (anxiety/depression, HADS-A/-D), PDQuestionnaire-8 (PDQ-8), Scales for Outcomes in PD-motor examination, motor complications, activities of daily living (ADL), and levodopa equivalent daily dose (LEDD) preoperatively and at 6 months follow-up...
March 16, 2018: Brain Stimulation
https://www.readbyqxmd.com/read/29651821/exploratory-factor-analysis-of-the-beck-anxiety-inventory-and-the-beck-depression-inventory-ii-in-a-psychiatric-outpatient-population
#5
Kounseok Lee, Daeho Kim, Yongrae Cho
BACKGROUND: To further understand the relationship between anxiety and depression, this study examined the factor structure of the combined items from two validated measures for anxiety and depression. METHODS: The participants were 406 patients with mixed psychiatric diagnoses including anxiety and depressive disorders from a psychiatric outpatient unit at a university-affiliated medical center. Responses of the Beck Anxiety Inventory (BAI), Beck Depression Inventory (BDI)-II, and Symptom Checklist-90-Revised (SCL-90-R) were analyzed...
April 16, 2018: Journal of Korean Medical Science
https://www.readbyqxmd.com/read/29649022/effectiveness-of-chinese-martial-arts-and-philosophy-to-reduce-reactive-and-proactive-aggression-in-schoolchildren
#6
Annis Lai Chu Fung, Toney Ka Hung Lee
OBJECTIVE: This study examined the effectiveness of Chinese martial arts in reducing reactive and proactive aggressive behavior among schoolchildren with a cluster-randomized trial. METHODS: A screening questionnaire was completed by 3511 schoolchildren of Grades 2 to 5 from 13 sites in Hong Kong. We shortlisted 298 children who scored z ≥ 1 on the total score of the Reactive-Proactive Aggression Questionnaire in their respective sites to participate in the experiment...
April 10, 2018: Journal of Developmental and Behavioral Pediatrics: JDBP
https://www.readbyqxmd.com/read/29643263/health-state-utilities-for-patient-s-current-health-from-bipolar-type-i-disorder
#7
Masoumeh Banihashemian, Arash Rashidian, Faeze Gholamian, Mahboubeh Parsaeian, Najmeh Moradi, Homayoun Amini
BACKGROUND: Bipolar Type I Disorder (BID) is a disabling mental disorder among young adults that places enormous psychological, social, and economic burdens on patients, their families, and health care systems and decreases quality of life (QOL). Few studies have investigated the quality-adjusted life-years (QALY), health state preferences, and utilities in patients with BID. AIM OF STUDY: The aim of this study was to elicit health state utilities for current health among a sample of individuals with BID irrespective of their clinical conditions at the time of evaluation...
March 1, 2018: Journal of Mental Health Policy and Economics
https://www.readbyqxmd.com/read/29643003/a-review-of-the-surface-features-and-properties-surfactant-adsorption-and-floatability-of-four-key-minerals-of-diasporic-bauxite-resources
#8
REVIEW
Ningning Zhang, Anh V Nguyen, Changchun Zhou
Diasporic bauxite represents one of the major aluminum resources. Its upgrading for further processing involves a separation of diaspore (the valuable mineral) from aluminosilicates (the gangue minerals) such as kaolinite, illite, and pyrophyllite. Flotation is one of the most effective ways to realize the upgrading. Since flotation is a physicochemical process based on the difference in the surface hydrophobicity of different components, determining the adsorption characteristics of various flotation surfactants on the mineral surfaces is critical...
March 27, 2018: Advances in Colloid and Interface Science
https://www.readbyqxmd.com/read/29629939/depressive-symptoms-antidepressant-use-and-hypertension-in-young-adulthood
#9
Danielle M Crookes, Ryan T Demmer, Katherine M Keyes, Karestan C Koenen, Shakira F Suglia
BACKGROUND: Among adults, depressive symptoms are associated with higher rates of cardiovascular disease; however, the evidence is mixed regarding the association between depressive symptoms and hypertension, especially among young adults. The deleterious effects of some antidepressant medications on blood pressure may contribute to mixed findings. METHODS: Adolescents enrolled in Add Health (N=11,183) (1994-2008) completed an abbreviated Center for Epidemiologic Studies Depression Scale at three waves (mean ages 16, 22, and 29)...
April 6, 2018: Epidemiology
https://www.readbyqxmd.com/read/29628175/syndemics-a-theory-in-search-of-data-or-data-in-search-of-a-theory
#10
Alexander C Tsai
The concept of a syndemic was proposed more than two decades ago to explain how large-scale social forces might give rise to co-occurring epidemics that synergistically interact to undermine health in vulnerable populations. This conceptual instrument has the potential to help policymakers and program implementers in their endeavors to improve population health. Accordingly, it has become an increasingly popular heuristic for advocacy, most notably in the field of HIV treatment and prevention. However, most empirical studies purporting to validate the theory of syndemics actually do no such thing...
March 30, 2018: Social Science & Medicine
https://www.readbyqxmd.com/read/29628063/cognitive-behavioral-therapy-is-associated-with-enhanced-cognitive-control-network-activity-in-major-depression-and-posttraumatic-stress-disorder
#11
Zhen Yang, Desmond J Oathes, Kristin A Linn, Steven E Bruce, Theodore D Satterthwaite, Philip A Cook, Emma K Satchell, Haochang Shou, Yvette I Sheline
BACKGROUND: Both major depressive disorder (MDD) and posttraumatic stress disorder (PTSD) are characterized by depressive symptoms, abnormalities in brain regions important for cognitive control, and response to cognitive behavioral therapy (CBT). However, whether a common neural mechanism underlies CBT response across diagnoses is unknown. METHODS: Brain activity during a cognitive control task was measured using functional magnetic resonance imaging in 104 participants: 28 patients with MDD, 53 patients with PTSD, and 23 healthy control subjects; depression and anxiety symptoms were determined on the same day...
April 2018: Biological Psychiatry: Cognitive Neuroscience and Neuroimaging
https://www.readbyqxmd.com/read/29627248/a-canonical-discriminant-analysis-to-study-the-association-between-milk-fatty-acids-of-ruminal-origin-and-milk-fat-depression-in-dairy-cows
#12
G Conte, C Dimauro, A Serra, N P P Macciotta, M Mele
Although milk fat depression (MFD) has been observed and described since the beginning of the last century, all the molecular and biochemical mechanisms involved are still not completely understood. Some fatty acids (FA) originating during rumen biohydrogenation have been proposed as causative elements of MFD. However, contradictory results were obtained when studying the effect of single FA on MFD. An alternative could be the simultaneous evaluation of the effect of many FA using a multivariate approach. The aim of this study was to evaluate the relationship between individual milk FA of ruminal origin and MFD using canonical discriminant analysis, a multivariate technique able to distinguish 2 or more groups on the basis of a pool of variables...
April 4, 2018: Journal of Dairy Science
https://www.readbyqxmd.com/read/29625800/reaction-time-and-brake-pedal-depression-following-arthroscopic-hip-surgery-a-prospective-case-control-study
#13
George C Balazs, Michael A Donohue, Alaina M Brelin, Daniel I Brooks, Michael P McCabe, Terrence D Anderson
PURPOSE: The purpose of this study was to determine whether patients diagnosed with femoroacetabular impingement (FAI) syndrome have prolonged braking times compared with age- and gender-matched controls and how long after surgery braking times return to preoperative baseline. METHODS: Fifty-nine patients undergoing arthroscopic hip surgery for FAI and 59 age- and gender-matched controls without FAI were enrolled in a prospective comparative study between September 2015 and October 2016...
April 3, 2018: Arthroscopy: the Journal of Arthroscopic & related Surgery
https://www.readbyqxmd.com/read/29624664/effectiveness-of-a-trauma-focused-group-intervention-for-young-refugees-a-randomized-controlled-trial
#14
Elisa Pfeiffer, Cedric Sachser, Friederike Rohlmann, Lutz Goldbeck
BACKGROUND: As access to evidence-based treatments for young refugees with posttraumatic stress symptoms (PTSS) is limited, we developed the trauma-focused group intervention Mein Weg to be delivered by trained social workers. A recently published pilot study delivered preliminary evidence of the intervention with regard to symptom reduction and its feasibility. The aim of this study was, therefore, to determine whether the intervention, in addition to usual care (UC), is more effective in reducing PTSS (primary outcome) compared to UC alone...
April 6, 2018: Journal of Child Psychology and Psychiatry, and Allied Disciplines
https://www.readbyqxmd.com/read/29623062/lucid-dreaming-intensity-but-not-frequency-is-inversely-related-to-psychopathology
#15
Liat Aviram, Nirit Soffer-Dudek
Lucid dreaming (LD) is awareness that one is dreaming, during the dream state. However, some define and assess LD relying also on controlling dream events, although control is present only in a subset of lucid dreams. LD has been claimed to represent well-being, and has even been used as a therapeutic agent. Conversely, LD is associated with mixed sleep-wake states, which are related to bizarre cognitions, stress, and psychopathology, and have been construed as arousal permeating and disrupting sleep. We propose that previous conflicting findings regarding relations between LD and both psychopathology and well-being, stem from the non-differentiated assessment of frequency and control...
2018: Frontiers in Psychology
https://www.readbyqxmd.com/read/29617889/insomnia-in-alcohol-dependent-patients-prevalence-risk-factors-and-acamprosate-effect-an-individual-patient-data-meta-analysis
#16
Pascal Perney, Philippe Lehert
Aims: The prevalence of insomnia ranges from 36% to 91% in alcohol-dependent patients and may persist after alcohol withdrawal. Acamprosate has been shown to decrease insomnia in abstinent patients. Based on a large clinical trial database, the aim of the present study is to assess the efficacy of acamprosate in reducing insomnia, and if indeed it does reduce insomnia, to better understand its action mechanism. Short Summary: The aim of the study is to confirm the efficacy of acamprosate to reduce insomnia using an individual patient data meta-analysis...
March 30, 2018: Alcohol and Alcoholism: International Journal of the Medical Council on Alcoholism
https://www.readbyqxmd.com/read/29617633/reducing-racial-ethnic-tobacco-cessation-disparities-via-cognitive-behavioral-therapy-design-of-a-dualsite-randomized-controlled-trial
#17
Monica Webb Hooper, David J Lee, Vani N Simmons, Karen O Brandon, Michael H Antoni, Marina Unrod, Taghrid Asfar, John B Correa, Tulay Koru-Sengul, Thomas H Brandon
Racial/ethnic disparities in tobacco cessation are such that U.S. minorities have greater difficulty quitting compared to White non-Hispanics. Group differences in distress (i.e., perceived stress and depressive symptoms) may contribute to cessation disparities. The allostasis model of health suggests that the toll of chronic stress experienced by racial/ethnic minorities may lead to dysregulation of the physiological stress system and drug use. Previous research suggests that group cognitive behavioral therapy (CBT) for tobacco cessation addresses distress as a modifiable mechanism and has the potential to reduce/eliminate disparities...
April 1, 2018: Contemporary Clinical Trials
https://www.readbyqxmd.com/read/29615136/promoting-psychosocial-well-being-following-stroke-study-protocol-for-a-randomized-controlled-trial
#18
Marit Kirkevold, Line Kildal Bragstad, Berit A Bronken, Kari Kvigne, Randi Martinsen, Ellen Gabrielsen Hjelle, Gabriele Kitzmüller, Margrete Mangset, Sanne Angel, Lena Aadal, Siren Eriksen, Torgeir B Wyller, Unni Sveen
BACKGROUND: Stroke is a major public health threat globally. Psychosocial well-being may be affected following stroke. Depressive symptoms, anxiety, general psychological distress and social isolation are prevalent. Approximately one third report depressive symptoms and 20% report anxiety during the first months or years after the stroke. Psychosocial difficulties may impact significantly on long-term functioning and quality of life, reduce the effects of rehabilitation services and lead to higher mortality rates...
April 3, 2018: BMC Psychology
https://www.readbyqxmd.com/read/29614992/a-research-study-review-of-effectiveness-of-treatments-for-psychiatric-conditions-common-to-end-stage-cancer-patients-needs-assessment-for-future-research-and-an-impassioned-plea
#19
Ralph J Johnson
BACKGROUND: Rates of psychiatric conditions common to end-stage cancer patients (delirium, depression, anxiety disorders) remain unchanged. However, patient numbers have increased as the population has aged; indeed, cancer is a chief cause of mortality and morbidity in older populations. Effectiveness of psychiatric interventions and research to evaluate, inform, and improve interventions is critical to these patients' care. This article's intent is to report results from a recent review study on the effectiveness of interventions for psychiatric conditions common to end-stage cancer patients; the review study assessed the state of research regarding treatment effectiveness...
April 3, 2018: BMC Psychiatry
https://www.readbyqxmd.com/read/29611892/mlc901-neuroaid-ii-%C3%A2-for-cognition-after-traumatic-brain-injury-a-pilot-randomised-clinical-trial
#20
Alice Theadom, Suzanne Barker-Collo, Kelly M Jones, Priya Parmar, Rohit Bhattacharjee, Valery L Feigin
BACKGROUND: Treatments to facilitate recovery after traumatic brain injury (TBI) are urgently needed. To examine the safety and potential effects of herbal supplement MLC901 (NeuroAiD IITM ) on cognitive functioning following TBI, we conducted a nine-month pilot, randomised placebo-controlled clinical trial. METHODS: Adults aged 18-65 years, 1-12-months post-mild or moderate TBI, were randomised to receive MLC901 (0.8g capsules/day) or placebo for 6-months. The primary outcome was cognitive functioning assessed by the CNS-Vital Signs online neuropsychological test...
April 3, 2018: European Journal of Neurology: the Official Journal of the European Federation of Neurological Societies
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