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journal of clinical neurophysiology

Miran Brvar, Ming Yin Chan, Andrew H Dawson, Richard R Ribchester, Michael Eddleston
INTRODUCTION: Treatment of acute organophosphorus or carbamate insecticide self-poisoning is often ineffective, with tens of thousands of deaths occurring every year. Researchers have recommended the addition of magnesium sulfate or calcium channel blocking drugs to standard care to reduce acetylcholine release at cholinergic synapses. OBJECTIVE: We aimed to review systematically the evidence from preclinical studies in animals exposed to organophosphorus or carbamate insecticides concerning the efficacy of magnesium sulfate and calcium channel blocking drugs as therapy compared with placebo in reducing mortality or clinical features of poisoning...
March 20, 2018: Clinical Toxicology
Lucio Marinelli, Maurizio Balestrino, Laura Mori, Luca Puce, Gian Marco Rosa, Laura Giorello, Antonio Currà, Francesco Fattapposta, Carlo Serrati, Carlo Gandolfo, Giovanni Abbruzzese, Carlo Trompetto
INTRODUCTION: Stroke is the most disabling neurological disorder and often causes spasticity. Transmucosal cannabinoids (tetrahydrocannabinol and cannabidiol (THC:CBD), Sativex) is currently available to treat spasticity-associated symptoms in patients with multiple sclerosis. Cannabinoids are being considered useful also in the treatment of pain, nausea and epilepsy, but may bear and increased risk for cardiovascular events. Spasticity is often assessed with subjective and clinical rating scales, which are unable to measure the increased excitability of the monosynaptic reflex, considered the hallmark of spasticity...
September 7, 2017: BMJ Open
Melissa Paniccia, David Paniccia, Scott Thomas, Tim Taha, Nick Reed
BACKGROUND: Heart rate variability (HRV), a measure of cardiac autonomic nervous system functioning, has emerged as a physiological indicator for emotional regulation and psychological well-being. HRV is understudied in the context of depression and anxiety in young people (10-24years old). Main objectives: (1) describe the nature and breadth of reviewed studies; and (2) synthesize main findings in the context of clinical and non-clinical populations of young people with depression and/or anxiety...
December 2017: Autonomic Neuroscience: Basic & Clinical
Joan Haliburn, Janine Stevenson, Shaun Halovic
The psychotherapy of commonly occurring severe personality disorders-borderline, narcissistic, avoidant, dependent, obsessive compulsive, and schizoid-presents the therapist with a unique therapeutic challenge, as each personality disorder rarely occurs alone. Integration of what is most useful and what works in each model is being proposed to enable a more successful approach to the diversity of presentations. We describe the conversational model, some outcome research, and descriptive studies to illustrate this...
February 2018: Journal of Personality Disorders
Timothy J Strauman
This article presents a general framework in which different manifestations of psychopathology can be conceptualized as dysfunctions in one or more mechanisms of self-regulation, defined as the ongoing process of managing personal goal pursuit in the face of internal, interpersonal, and environmental forces that would derail it. The framework is based on the assertion that self-regulation is a critical locus for the proximal influence on motivation, cognition, emotion, and behavior of more distal factors such as genetics, temperament, socialization history, and neurophysiology...
May 8, 2017: Annual Review of Clinical Psychology
Agustina M Lascano, Patrice H Lalive, Martin Hardmeier, Peter Fuhr, Margitta Seeck
Evoked potentials (EPs) are a powerful and cost-effective tool for evaluating the integrity and function of the central nervous system. Although imaging techniques, such as MRI, have recently become increasingly important in the diagnosis of neurological diseases, over the past 30 years, many neurologists have continued to employ EPs in specific clinical applications. This review presents an overview of the recent evolution of 'classical' clinical applications of EPs in terms of early diagnosis and disease monitoring and is an extension of a previous review published in this journal in 2005 by Walsh and collaborators...
August 2017: Journal of Neurology, Neurosurgery, and Psychiatry
Yuguang Chen, Baoqing P Wang, Junlin Yang, Yaolong Deng
INTRODUCTION: Intraoperative neurophysiological monitoring (IONM) has proven to help reduce the probability of postoperative neurological deficit for spinal deformity correctional surgeries. However, in rare cases new deficits may still happen. We report a surgical case in which the patient had postoperative paralysis. We would like to call for more case reports with postoperative neurological deficits as they present difficult clinical cases. PRESENTATION OF CASE: A 61-year-old male patient with severe thoracolumbar kyphoscoliosis underwent posterior spinal correction and fusion with segmental T10-L5 pedicle screws and rods instrumentation with IONM...
2017: International Journal of Surgery Case Reports
Julie L Ji, Stephanie Burnett Heyes, Colin MacLeod, Emily A Holmes
This article pays tribute to the seminal paper by Peter J. Lang (1977; this journal), "Imagery in Therapy: Information Processing Analysis of Fear." We review research and clinical practice developments in the past five decades with reference to key insights from Lang's theory and experimental work on emotional mental imagery. First, we summarize and recontextualize Lang's bio-informational theory of emotional mental imagery (1977, 1979) within contemporary theoretical developments on the function of mental imagery...
September 2016: Behavior Therapy
Aatif M Husain
No abstract text is available yet for this article.
August 2016: Journal of Clinical Neurophysiology: Official Publication of the American Electroencephalographic Society
Michelle Ciucci, Corinne A Jones, Georgia A Malandraki, Katherine A Hutcheson
Dysphagia evaluation and management has rapidly become the primary practice area of medical speech pathologists since its adoption in our field less than three decades ago. As a specialty, swallowing and swallowing disorders comprise the largest represented discipline with 10,059 specialty interest group members within the American Speech-Language-Hearing Association and 298 board-certified specialists in the American Speech Hearing Association. There are national and international organizations, such as the Dysphagia Research Society and its interdisciplinary journal Dysphagia, that provide continuing education for clinicians and a platform for dysphagia researchers...
August 2016: Seminars in Speech and Language
Jun Gao, Xiangyi Kong, Yi Yang, Wenbin Ma, Renzhi Wang, Yongning Li
Lipomyelocele is an uncommon type of lipoma that occurs with spina bifida. We present the clinical course and therapeutic process of a female who underwent resection of a lipomyelocele and developed a massive lumbosacral subcutaneous exudate postoperatively. The therapeutic process is described in detail, and a review of the relevant literature on lipomyelocele is presented. A 23-year-old woman presented to our institution complaining of a large lumbosacral subcutaneous mass. She underwent surgical resection of the mass and untethering of the spinal cord under intraoperative neurophysiologic monitoring...
September 2015: Medicine (Baltimore)
Véronique Bissay, Sophie C H Van Malderen, Kathelijn Keymolen, Willy Lissens, Uschi Peeters, Dorien Daneels, Anna C Jansen, Gudrun Pappaert, Pedro Brugada, Jacques De Keyser, Sonia Van Dooren
SCN5A mutations involving the α-subunit of the cardiac voltage-gated muscle sodium channel (NaV1.5) result in different cardiac channelopathies with an autosomal-dominant inheritance such as Brugada syndrome. On the other hand, mutations in SCN4A encoding the α-subunit of the skeletal voltage-gated sodium channel (NaV1.4) cause non-dystrophic myotonia and/or periodic paralysis. In this study, we investigated whether cardiac arrhythmias or channelopathies such as Brugada syndrome can be part of the clinical phenotype associated with SCN4A variants and whether patients with Brugada syndrome present with non-dystrophic myotonia or periodic paralysis and related gene mutations...
March 2016: European Journal of Human Genetics: EJHG
Jacob Juel, Søren Schou Olesen, Anne Estrup Olesen, Jakob Lykke Poulsen, Albert Dahan, Oliver Wilder-Smith, Adnan Madzak, Jens Brøndum Frøkjær, Asbjørn Mohr Drewes
INTRODUCTION: Chronic pancreatitis (CP) is an inflammatory disease that causes irreversible damage to pancreatic tissue. Pain is its most prominent symptom. In the absence of pathology suitable for endoscopic or surgical interventions, pain treatment usually includes opioids. However, opioids often have limited efficacy. Moreover, side effects are common and bothersome. Hence, novel approaches to control pain associated with CP are highly desirable. Sensitisation of the central nervous system is reported to play a key role in pain generation and chronification...
March 10, 2015: BMJ Open
Aatif M Husain
No abstract text is available yet for this article.
February 2015: Journal of Clinical Neurophysiology: Official Publication of the American Electroencephalographic Society
Aatif M Husain
No abstract text is available yet for this article.
April 2014: Journal of Clinical Neurophysiology: Official Publication of the American Electroencephalographic Society
Cesar Fernández-de-Las-Peñas
Cesar Fernández-de-las-Peñas completed his Bachelor's degree in Physical Therapy in 2000, in Spain. He obtained his first PhD degree in Biomedical Sciences in 2007, under the supervision of Dr Lars Arendt-Nielsen at the Sensory-Motor Interaction Center at the University of Aalborg (Denmark). In 2008, he obtained his second PhD degree in Preventive Medicine, under the supervision of Drs Pareja and Cuadrado in Spain. He is the Head of the Division of the Department of Physical Therapy, Occupational Therapy, Rehabilitation and Physical Medicine at Universidad Rey Juan Carlos, Spain...
March 2012: Pain Management
Nanna Finnerup
Nanna Finnerup graduated from the Medical School at Aarhus University, Denmark, in 1993, and after an internship worked at the Department of Neurology and Clinical Neurophysiology at the University of Copenhagen, Denmark. Since 1998 she has worked at the Danish Pain Research Center at Aarhus University. She obtained her degree of Doctor of Medical Sciences from Aarhus University in 2008, and is currently Associate Research Professor at the Danish Pain Research Center. Her main research interest is the pathophysiology and therapy of neuropathic pain, with particular focus on the mechanisms of central pain and pharmacological treatment of neuropathic pain...
November 2011: Pain Management
Paul A Lapchak
The approval of new therapies to treat neurodegenerative disease conditions by the Food and Drug administration (FDA) has been hindered by many failed clinical trials, which were based upon "significant" efficacy in preclinical or translational studies. Additional problems during drug development related to significant adverse events and unforeseen toxicity have also hampered drug development. Recent reviews of preclinical data suggests that many studies have over-estimated efficacy due to poor or inadequate study design, exclusion of important data (negative or neutral) and lack of study randomization and blinding...
2012: Journal of Neurology & Neurophysiology
Peter W Kaplan, Raoul Sutter
Patients with acute confusional states (often referred to as encephalopathy or delirium) pose diagnostic and management challenges for treating physicians. Encephalopathy is associated with a high morbidity and mortality rate, and the diagnosis rests on clinical grounds but may also be supported by the finding of electroencephalographic (EEG) evidence for diffuse cerebral dysfunction. The myriad cerebral transmitter and metabolic disruptions are generated by systemic organ system failures, principal among which are those of the liver, kidneys, lungs, heart, and endocrine system, along with the effects of exogenous toxins and medications...
October 2013: Journal of Clinical Neurophysiology: Official Publication of the American Electroencephalographic Society
Maryam Abbaszadeh-Amirdehi, Noureddin Nakhostin Ansari, Soofia Naghdi, Gholamreza Olyaei, Mohammad Reza Nourbakhsh
INTRODUCTION: Dry needling (DN) is an effective method for the treatment of myofascial trigger points (MTrPs). There is no report on the neurophysiological effects of DN in patients with MTrPs. The aim of the present study will be to assess the immediate neurophysiological efficacy of deep DN in patients with upper trapezius MTrPs. METHODS AND ANALYSIS: A prospective, controlled clinical trial was designed to include patients with upper trapezius MTrPs and volunteered healthy participants to receive one session of DN...
2013: BMJ Open
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