keyword
https://read.qxmd.com/read/38656791/microstructural-brain-abnormalities-and-associated-neurocognitive-dysfunction-in-obstructive-sleep-apnea-a-pilot-study-with-diffusion-kurtosis-imaging
#1
JOURNAL ARTICLE
Ning Zhang, Kun Peng, Jin-Xia Guo, Qing Liu, Ai-Lian Xiao, Hui Jing
STUDY OBJECTIVES: To assess the possible brain abnormalities in adult patients with moderate and severe obstructive sleep apnea (OSA) using the mean kurtosis (MK) from diffusion kurtosis imaging (DKI) and analyze the correlation between MK and cognitive function. METHODS: A total of 30 patients with moderate and severe OSA and 30 healthy controls (HCs) evaluated by the Montreal Cognitive Assessment (MoCA) scale were enrolled. All subjects underwent DKI and 3D T1-weighted imaging (T1WI) on a 3...
April 24, 2024: Journal of Clinical Sleep Medicine: JCSM: Official Publication of the American Academy of Sleep Medicine
https://read.qxmd.com/read/38655611/pharmacokinetics-and-pharmacodynamics-of-dextroketamine-alone-or-combined-with-midazolam-in-caiman-crocodilus
#2
JOURNAL ARTICLE
Líria Queiroz Luz Hirano, Adrielly Lorena Rodrigues de Oliveira, Rafael Ferraz de Barros, Danillo Fabrini Maciel Costa Veloso, Eliana Martins Lima, André Luiz Quagliatto Santos, Juan Carlos Duque Moreno
Pharmacokinetics studies of anesthetic agents are important for understanding of the pharmacology and metabolism of anesthetic agents in reptilians. This study was designed to examine the pharmacokinetic and pharmacodynamic properties of intravenous dextroketamine alone or combined with midazolam in Caiman crocodilus. Eight caimans were anesthetized with dextroketamine (10 mg/kg; group D) or dextroketamine and midazolam (10 and 0.5 mg/kg respectively; group DM) into the occipital venous sinus...
April 24, 2024: Journal of Veterinary Pharmacology and Therapeutics
https://read.qxmd.com/read/38654366/exploring-morphological-similarity-and-randomness-in-alzheimer-s-disease-using-adjacent-grey-matter-voxel-based-structural-analysis
#3
JOURNAL ARTICLE
Ting-Yu Chen, Jun-Ding Zhu, Shih-Jen Tsai, Albert C Yang
BACKGROUND: Alzheimer's disease is characterized by large-scale structural changes in a specific pattern. Recent studies developed morphological similarity networks constructed by brain regions similar in structural features to represent brain structural organization. However, few studies have used local morphological properties to explore inter-regional structural similarity in Alzheimer's disease. METHODS: Here, we sourced T1-weighted MRI images of 342 cognitively normal participants and 276 individuals with Alzheimer's disease from the Alzheimer's Disease Neuroimaging Initiative database...
April 23, 2024: Alzheimer's Research & Therapy
https://read.qxmd.com/read/38654234/implications-of-depressive-mood-in-osahs-patients-insights-from-event-related-potential
#4
JOURNAL ARTICLE
Zhiqiang Li, Sijie Cai, Jiamin Qiao, Yezhou Li, Qiaojun Wang, Rui Chen
BACKGROUND: Obstructive sleep apnea-hypopnea syndrome (OSAHS) is a chronic breathing disorder characterized by recurrent upper airway obstruction during sleep. Although previous studies have shown a link between OSAHS and depressive mood, the neurobiological mechanisms underlying mood disorders in OSAHS patients remain poorly understood. This study aims to investigate the emotion processing mechanism in OSAHS patients with depressive mood using event-related potentials (ERPs). METHODS: Seventy-four OSAHS patients were divided into the depressive mood and non-depressive mood groups according to their Self-rating Depression Scale (SDS) scores...
April 23, 2024: BMC Psychiatry
https://read.qxmd.com/read/38653915/aberrant-functional-connectivity-associated-with-drug-response-in-patients-with-newly-diagnosed-epilepsy
#5
JOURNAL ARTICLE
Haijiao Wang, Ge Tan, Xiuli Li, Deng Chen, Dongmei An, Qiyong Gong, Ling Liu
OBJECTIVE: To analyze the local functional activity and connectivity features of the brain associated with drug response inpatients newly diagnosed with epilepsy (NDE) who are naïve to anti-seizure medication (ASM). METHODS: Recruited patients, underwent functional magnetic resonance imaging at baseline, and were assigned to the well-controlled (WC, n = 28) or uncontrolled (UC, n = 11) groups based on their response to ASM. Healthy participants were included in the control group (HC, n = 29)...
April 24, 2024: Neurological Sciences
https://read.qxmd.com/read/38653349/the-functional-connectivity-of-the-right-superior-temporal-gyrus-is-associated-with-psychological-risk-and-resilience-factors-for-suicidality
#6
JOURNAL ARTICLE
Giulia Cattarinussi, Nicola Meda, Alessandro Miola, Fabio Sambataro
INTRODUCTION: Suicide attempters show increased activation in the right superior temporal gyrus (rSTG). Here, we investigated the rSTG functional connectivity (FC) to identify a functional network involved in suicidality and its associations with psychological suicidality risk and resilience factors. METHODS: The resting state functional magnetic resonance imaging data of 151 healthy individuals from the Human Connectome Project Young Adult database were used to explore the FC of the rSTG with itself and with the rest of the brain...
April 21, 2024: Journal of Affective Disorders
https://read.qxmd.com/read/38652513/altered-functional-connectivity-strength-of-primary-visual-cortex-in-subjects-with-thyroid-associated-ophthalmopathy
#7
JOURNAL ARTICLE
Chen-Xing Qi, Zhi Wen, Xin Huang
Our objective was to explore the disparities in the intrinsic functional connectivity (FC) patterns of primary visual cortex (V1) between patients with thyroid-associated ophthalmopathy (TAO) and healthy controls (HCs) utilizing resting-state functional MRI. Twenty-one patients with TAO (14 males and 7 females; mean age: 54.17 ± 4.83 years) and 21 well-matched HCs (14 males and 7 females; mean age: 55.17 ± 5.37 years) underwent functional MRI scans in the resting-state...
April 17, 2024: Neuroreport
https://read.qxmd.com/read/38652252/a-rare-variation-of-the-infraorbital-nerve-entrapping-the-infraorbital-artery
#8
JOURNAL ARTICLE
D Stoyanov
Anatomical variations are a common feature of the human anatomy. Variation can explain some pathological conditions and is important to keep them in mind during surgical procedures. The relations between nerves and their adjacent arteries have been proposed to play a role in the generation of peripheral trigger migraines. Close opposition between nerves and arteries can lead to vascular compression of the nerve that triggers episodes of pain. We did a routine dissection of the infratemporal fossa and orbital floor by opening the maxillary sinus...
April 23, 2024: Surgical and Radiologic Anatomy: SRA
https://read.qxmd.com/read/38652097/speaker-competence-affects-prefrontal-theta-and-occipital-alpha-power-during-selective-word-learning-in-preschoolers
#9
JOURNAL ARTICLE
Julia Brehm, Liridona Hoti, Myriam C Sander, Markus Werkle-Bergner, Anja Gampe, Moritz M Daum
In the present study, we investigated the cognitive processes underlying selective word learning in preschoolers. We measured rhythmic neural activity in the theta (4-8 Hz) and alpha frequency range (7-12 Hz) in 67 four-year-olds. EEG was recorded during anticipation and encoding of novel labeling events performed by a speaker who had previously shown either competence (correct) or incompetence (incorrect) in labeling familiar objects. In both groups, children selected the target object equally often upon recall...
April 22, 2024: Journal of Cognitive Neuroscience
https://read.qxmd.com/read/38651950/evaluation-of-mental-load-using-eeg-and-eye-movement-characteristics
#10
JOURNAL ARTICLE
Xin Zheng, Huiyu Wang, Tengteng Hao, Shoukun Chen, Kaili Xu, Yicheng Wang
Mental load is a major cause of human-induced accidents. In this study, an explosive impact sensitivity experiment was used to induce mental load. A combination of subjective questionnaires and objective prospective time-distance tests were used to judge whether subjects experienced mental load. Four indicators, namely, β, γ, mean pupil diameter, and fixation time were selected by statistical analysis and PCA for the construction of a mental load assessment model. The study found that the occipital lobe was the most sensitive to mental load, especially β and γ bands...
April 23, 2024: Ergonomics
https://read.qxmd.com/read/38651756/strategic-white-matter-hyperintensity-locations-associated-with-post-stroke-cognitive-impairment-a-multicenter-study-in-1568-stroke-patients
#11
JOURNAL ARTICLE
Mirthe Coenen, Floor A S de Kort, Nick A Weaver, Hugo J Kuijf, Hugo Paul Aben, Hee-Joon Bae, Régis Bordet, Christopher Lh Chen, Anna Dewenter, Thomas Doeven, Thibaut Dondaine, Marco Duering, Rong Fang, Ruben S van der Giessen, Jonguk Kim, Beom Joon Kim, Paul L M de Kort, Peter Koudstaal, Minwoo Lee, Jae-Sung Lim, Renaud Lopes, Robert J van Oostenbrugge, Julie Staals, Kyung-Ho Yu, Geert Jan Biessels, J Matthijs Biesbroek
BACKGROUND: Post-stroke cognitive impairment (PSCI) occurs in up to 50% of stroke survivors. Presence of pre-existing vascular brain injury, in particular the extent of white matter hyperintensities (WMH), is associated with worse cognitive outcome after stroke, but the role of WMH location in this association is unclear. AIM: We determined if WMH in strategic white matter tracts explain cognitive performance after stroke. METHODS: Individual patient data from 9 ischemic stroke cohorts with MRI were harmonized through the Meta VCI Map consortium...
April 23, 2024: International Journal of Stroke: Official Journal of the International Stroke Society
https://read.qxmd.com/read/38651499/decompressive-craniectomy-incisions-all-roads-lead-to-bone
#12
REVIEW
Riccardo Serra, Timothy Chryssikos
INTRODUCTION: Decompressive craniectomy and craniotomy are among the most common procedures in Neurosurgery. In recent years, increased attention has focused on the relationships between incision type, extent of decompression, vascular supply to the scalp, cosmetic outcomes, and complications. Here, we review the current literature on scalp incisions for large unilateral front-temporo-parietal craniotomies and craniectomies. METHODS: Publications in the past 50 years on scalp incisions used for front-temporo-parietal craniectomies/craniotomies were reviewed...
April 23, 2024: British Journal of Neurosurgery
https://read.qxmd.com/read/38651161/distinct-patterns-of-voxel-and-connection-based-white-matter-hyperintensity-distribution-and-associated-factors-in-early-onset-and-late-onset-alzheimer-s-disease
#13
JOURNAL ARTICLE
Hui Hong, Yutong Chen, Weiran Liu, Xiao Luo, Minming Zhang
INTRODUCTION: The distribution of voxel- and connection-based white matter hyperintensity (WMH) patterns in early-onset Alzheimer's disease (EOAD) and late-onset Alzheimer's disease (LOAD), as well as factors associated with these patterns, remain unclear. METHOD: We analyzed the WMH distribution patterns in EOAD and LOAD at the voxel and connection levels, each compared with their age-matched cognitively unimpaired participants. Linear regression assessed the independent effects of amyloid and vascular risk factors on WMH distribution patterns in both groups...
2024: Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring
https://read.qxmd.com/read/38651071/evolutionary-origin-of-alpha-rhythms-in-vertebrates
#14
REVIEW
Takashi Shibata, Noriaki Hattori, Hisao Nishijo, Satoshi Kuroda, Kaoru Takakusaki
The purpose of this review extends beyond the traditional triune brain model, aiming to elucidate the evolutionary aspects of alpha rhythms in vertebrates. The forebrain, comprising the telencephalon (pallium) and diencephalon (thalamus, hypothalamus), is a common feature in the brains of all vertebrates. In mammals, evolution has prioritized the development of the forebrain, especially the neocortex, over the midbrain (mesencephalon) optic tectum, which serves as the prototype for the visual brain. This evolution enables mammals to process visual information in the retina-thalamus (lateral geniculate nucleus)-occipital cortex pathway...
2024: Frontiers in Behavioral Neuroscience
https://read.qxmd.com/read/38650568/two-step-effective-onyx-embolization-from-the-occipital-artery-for-the-treatment-of-intracranial-dural-arteriovenous-fistula-a-technical-note
#15
JOURNAL ARTICLE
Shoko Fujii, Sakyo Hirai, Kyohei Fujita, Hiroto Yamaoka, Mariko Ishikawa, Jiro Aoyama, Hirotaka Sagawa, Kazunori Miki, Shigeru Nemoto, Kazutaka Sumita
AIM: Trans-arterial embolization (TAE) using Onyx has recently been recognized as a curative treatment for dural arteriovenous fistulas (DAVFs). However, TAE for DAVFs with feeders from the occipital artery (OA) remains challenging because of the tiny and transosseous properties of the OA feeders. We report our experience and the technique of two-step effective Onyx embolization from OA for the obliteration of DAVFs with OA feeders. MATERIAL AND METHODS: The medical records of patients with intracranial DAVFs treated with TAE using Onyx from the OA were retrospectively reviewed...
July 31, 2023: Turkish Neurosurgery
https://read.qxmd.com/read/38650040/clinical-pathologic-and-genomic-characteristics-of-two-pediatric-glioneuronal-tumors-with-a-clip2-met-fusion
#16
JOURNAL ARTICLE
Nicholas Chapman, Joshua Greenwald, Jolee Suddock, Dong Xu, Alexander Markowitz, Maeve Humphrey, Jennifer A Cotter, Mark D Krieger, Debra Hawes, Jianling Ji
Integration of molecular data with histologic, radiologic, and clinical features is imperative for accurate diagnosis of pediatric central nervous system (CNS) tumors. Whole transcriptome RNA sequencing (RNAseq), a genome-wide and non-targeted approach, allows for the detection of novel or rare oncogenic fusion events that contribute to the tumorigenesis of a substantial portion of pediatric low- and high-grade glial and glioneuronal tumors. We present two cases of pediatric glioneuronal tumors occurring in the occipital region with a CLIP2::MET fusion detected by RNAseq...
April 22, 2024: Acta Neuropathologica Communications
https://read.qxmd.com/read/38649990/use-of-bone-landmarks-for-assessing-the-safety-of-acupuncture-on-the-posterior-midline-of-the-neck-region
#17
JOURNAL ARTICLE
Zhiliang Tang, Jiao Liu, Jin Li, Chunming Ma
OBJECTIVE: Many acupuncture acupoints are located on the posterior midline of the neck region. The needling depth for acupuncture is important for practitioners, and an unsafe needling depth increases the possibility of damage to the spinal cord and brainstem. Can the safety of acupuncture be assessed by examining bone structures? We focused on this aim to carry out this study. METHODS: The shortest distance from the posterior border of the foramen magnum to the line joining both upper ends of the posterior border of the mastoid process was measured on 29 skulls...
April 22, 2024: BMC complementary medicine and therapies
https://read.qxmd.com/read/38649694/prediction-error-processing-and-sharpening-of-expected-information-across-the-face-processing-hierarchy
#18
JOURNAL ARTICLE
Annika Garlichs, Helen Blank
The perception and neural processing of sensory information are strongly influenced by prior expectations. The integration of prior and sensory information can manifest through distinct underlying mechanisms: focusing on unexpected input, denoted as prediction error (PE) processing, or amplifying anticipated information via sharpened representation. In this study, we employed computational modeling using deep neural networks combined with representational similarity analyses of fMRI data to investigate these two processes during face perception...
April 22, 2024: Nature Communications
https://read.qxmd.com/read/38649377/common-risk-alleles-for-schizophrenia-within-the-major-histocompatibility-complex-predict-white-matter-microstructure
#19
JOURNAL ARTICLE
Xavier Caseras, Emily Simmonds, Antonio F Pardiñas, Richard Anney, Sophie E Legge, James T R Walters, Neil A Harrison, Michael C O'Donovan, Valentina Escott-Price
Recent research has highlighted the role of complement genes in shaping the microstructure of the brain during early development, and in contributing to common allele risk for Schizophrenia. We hypothesised that common risk variants for schizophrenia within complement genes will associate with structural changes in white matter microstructure within tracts innervating the frontal lobe. Results showed that risk alleles within the complement gene set, but also intergenic alleles, significantly predict axonal density in white matter tracts connecting frontal cortex with parietal, temporal and occipital cortices...
April 22, 2024: Translational Psychiatry
https://read.qxmd.com/read/38649026/predicting-the-need-for-occipitocervical-fusion-for-patients-with-lower-clival-chordoma-a-single-center-retrospective-study
#20
JOURNAL ARTICLE
Sukwoo Hong, Yuki Shinya, Nikita Lakomkin, Anita Mahajan, Nadia N Laack, Erin O'Brien, Janalee K Stokken, Jeffrey R Janus, Carlos Pinheiro Neto, Garret W Choby, Maria Peris Celda, Michael J Link, Benjamin D Elder, Jamie J Van Gompel
OBJECTIVE: To assess the impact of tumor extension into the occipital condyle (OC) in lower clival chordoma management and the need for occipito-cervical fusion (OCF). METHODS: A retrospective analysis was conducted on 35 patients with lower clival chordoma. The preoperative area of the intact OCs, Hounsfield units, and the integrity of the apical ligament and the tectorial membrane were assessed using preoperative imaging. RESULTS: Seven (20%) patients were in the OCF group...
April 20, 2024: World Neurosurgery
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