Purevsuren Losol, Milena Sokolowska, Yu-Kyoung Hwang, Ismail Ogulur, Yasutaka Mitamura, Duygu Yazici, Yagiz Pat, Urszula Radzikowska, Sena Ardicli, Jeong-Eun Yoon, Jun-Pyo Choi, Sae-Hoon Kim, Willem van de Veen, Mübeccel Akdis, Yoon-Seok Chang, Cezmi A Akdis
Allergic diseases are a major public health problem with increasing prevalence. These immune-mediated diseases are characterized by defective epithelial barriers, which are explained by the epithelial barrier theory and continuously emerging evidence. Environmental exposures (exposome) including global warming, changes and loss of biodiversity, pollution, pathogens, allergens and mites, laundry and dishwasher detergents, surfactants, shampoos, body cleaners and household cleaners, microplastics, nanoparticles, toothpaste, enzymes and emulsifiers in processed foods, and dietary habits are responsible for the mucosal and skin barrier disruption...
November 2023: Allergy, Asthma & Immunology Research