Elisa Choukroun, Maximilien Parnot, Jerome Surmenian, Reinhard Gruber, Nicolas Cohen, Nicolas Davido, Alain Simonpieri, Charles Savoldelli, Franck Afota, Hicham El Mjabber, Joseph Choukroun
Based on the evidence of a significant communication and connection pathway between the bone and immune systems, a new science has emerged: osteoimmunology. Indeed, the immune system has a considerable impact on bone health and diseases, as well as on bone formation during grafts and its stability over time. Chronic inflammation induces the excessive production of oxidants. An imbalance between the levels of oxidants and antioxidants is called oxidative stress. This physio-pathological state causes both molecular and cellular damage, which leads to DNA alterations, genetic mutations and cell apoptosis, and thus, impaired immunity followed by delayed or compromised wound healing...
February 16, 2024: Bioengineering