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https://www.readbyqxmd.com/read/29324910/deep-brain-nucleus-targeting-in-parkinson-s-disease-and-essential-tremor-by-image-guided-surgery-using-neuronavigation-system-with-tractography-and-volume-of-tissue-of-activated-assessment
#1
Amir Nikouei, Pooya Torkian, Tohid Emami Meybodi, Arash Javad Mousavi, Amir Saied Seddighi
OBJECTIVE: Deep Brain Stimulation (DBS) is an effective surgical approach for treatment of Parkinson's disease (PD), dystonia and essential tremor (ET). Traditionally, DBS is performed using frame-based stereotactic technique. Recently, image guided surgery (IGS) using neuronavigation has gained popularity in neurosurgical procedures. We aim to investigate whether DBS using neuronavigation is capable of improving patient's outcome and minimize its complications. SUBJECT AND METHODS: From February 2011 to October 2016, 20 patients with PD and 6 patients with ET were enrolled in the study...
September 2017: Hellenic Journal of Nuclear Medicine
https://www.readbyqxmd.com/read/29324357/a-pilot-study-of-the-role-of-the-claustrum-in-attention-and-seizures-in-rats
#2
Arezou Bayat, Sweta Joshi, Sahar Jahan, Phillip Connell, Komei Tsuchiya, David Chau, Tanvir Syed, Patrick Forcelli, Mohamad Z Koubeissi
OBJECTIVE: The claustrum has been implicated in consciousness, and MRIs of patients with status epilepticus have shown increased claustral signal intensity. In an attempt to investigate the role of claustrum in cognition and seizures, we (1) assessed the effect of high-frequency stimulation (HFS) of the claustrum on performance in the operant chamber; (2) studied interclaustral and claustrohippocampal connectivity through cerebro-cerebral evoked potentials (CCEPs); and (3) investigated the role of claustrum in kainate-induced (KA) seizures...
January 5, 2018: Epilepsy Research
https://www.readbyqxmd.com/read/29321813/novel-concept-of-a-modular-hip-implant-could-contribute-to-less-implant-failure-in-tha-a-hypothesis
#3
Ronny Grunert, Stefan Schleifenbaum, Robert Möbius, Michael Kopper, Christian Rotsch, Welf-Guntram Drossel, Niels Hammer, Torsten Prietzel
Background: The modularity in total hip arthroplasty (THA) allows orthopaedic surgeons for an exact reconstruction of hip biomechanical parameters especially in revision and tumor arthroplasty. Modular structured femoral stems using taper junctions showed increased implant breakage in the recent past. Presentation of the hypothesis: We hypothesize that a novel modular stem-neck-interface leads to less implant breakage compared to conventional femoral stems. Testing of the hypothesis: For this purpose, a novel modular femoral stem for THA was to design and manufacture...
2018: Patient Safety in Surgery
https://www.readbyqxmd.com/read/29321138/sensorimotor-functional-and-structural-networks-after-intracerebral-stem-cell-grafts-in-the-ischemic-mouse-brain
#4
Claudia Green, Anuka Minassian, Stefanie Vogel, Michael Diedenhofen, Andreas Beyrau, Dirk Wiedermann, Mathias Hoehn
Past investigations on stem cell mediated recovery after stroke have limited their focus on the extent and morphological development of the ischemic lesion itself over time or on the integration capacity of the stem cell graft ex vivo However, an assessment of the long-term functional and structural improvement in vivo is essential to reliably quantify the regenerative capacity of cell implantation after stroke.We induced ischemic stroke in nude mice and implanted human neural stem cells (H9 derived) into the ipsilateral cortex in the acute phase...
January 10, 2018: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
https://www.readbyqxmd.com/read/29313133/influence-of-subcrestal-implant-placement-compared-with-equicrestal-position-on-the-peri-implant-hard-and-soft-tissues-around-platform-switched-implants-a-systematic-review-and-meta-analysis
#5
REVIEW
Cristina Valles, Xavier Rodríguez-Ciurana, Marco Clementini, Mariana Baglivo, Blanca Paniagua, Jose Nart
AIM: The aim of this article is to systematically review the effect of subcrestal implant placement compared with equicrestal position on hard and soft tissues around dental implants with platform switch. MATERIAL AND METHODS: A manual and electronic search (National Library of Medicine and Cochrane Central Register of Controlled Trials) was performed for animal and human studies published up to December 2016. Primary outcome variable was marginal bone level (MBL) and secondary outcomes were crestal bone level (CBL), soft tissue dimensions (barrier epithelium, connective tissue, and peri-implant mucosa), and changes in the position of soft tissue margin...
January 8, 2018: Clinical Oral Investigations
https://www.readbyqxmd.com/read/29310906/development-of-layered-plga-membranes-for-periodontal-tissue-regeneration
#6
Itsumi Yoshimoto, Jun-Ichi Sasaki, Ririko Tsuboi, Satoshi Yamaguchi, Haruaki Kitagawa, Satoshi Imazato
OBJECTIVE: Various commercial products are available for guided tissue regeneration (GTR) therapy; however, they do not combine biosafety with the ability to control cell function. The purpose of this study was to evaluate the physicochemical and biological characteristics of the novel bilayer biodegradable poly(lactic-co-glycolic acid) (PLGA) membrane, and to assess whether the bilayer PLGA membrane could be used for periodontal tissue regeneration. METHODS: Bilayer biodegradable membrane was fabricated thorough a two-step freezing and lyophilization process using PLGA solution...
January 5, 2018: Dental Materials: Official Publication of the Academy of Dental Materials
https://www.readbyqxmd.com/read/29310880/the-hemi-engaging-fixed-dental-implant-prosthesis-a-technique-for-improved-stability-and-handling
#7
Todd R Schoenbaum, Richard G Stevenson, Eric Balinghasay
Clinicians commonly contend that the screw-retained, implant-supported fixed dental prosthesis (FDP) should be fabricated with all nonengaging abutments to allow for the inherent nonparallelism of the implants and the inability of the abutment connections to draw together during insertion and removal. The problem with a fully nonengaging FDP is difficulty in handling and more strain on the abutment screws, ultimately leading to increased rates of breakage and loosening. The hemi-engaging FDP design regains much of the advantage afforded by the internal connection and improves prosthetic handing both clinically and in the laboratory...
January 5, 2018: Journal of Prosthetic Dentistry
https://www.readbyqxmd.com/read/29303111/chronic-implantation-of-cuff-electrodes-on-the-pelvic-nerve-in-rats-is-well-tolerated-and-does-not-compromise-afferent-or-efferent-fibre-functionality
#8
Jonathan J Crook, Charly Brouillard, Pedro Irazoqui, Thelma Lovick
Objective Neuromodulation of autonomic nerve activity to regulate physiological processes is an emerging field. Vagal stimulation has received most attention whereas the potential of modulate visceral function by targeting autonomic nerves within the abdominal cavity remains under-exploited. Surgery to locate intra-abdominal targets is inherently more stressful than for peripheral nerves. Electrode leads risk becoming entrapped by intestines and loss of functionality in the nerve-target organ connection could result from electrode migration or twisting...
January 5, 2018: Journal of Neural Engineering
https://www.readbyqxmd.com/read/29302289/preload-loss-of-abutment-screws-after-dynamic-fatigue-in-single-implant-supported-restorations-a-systematic-review
#9
REVIEW
Beatriz Pardal-Peláez, Javier Montero
Background: To carry out a systematic literature review of the causes of preload loss of the abutment screws, of internal and external connection implants, tightened to different torque values and subjected to cyclic loading. Material and Methods: A systematic search was conducted in PubMed, EMBASE, and Cochrane Library databases with reference to in vitro studies in which internal and external connection implants were subjected to cyclic loads to determine the degree of loosening of the abutment screws after loading...
November 2017: Journal of Clinical and Experimental Dentistry
https://www.readbyqxmd.com/read/29301458/deep-analysis-of-n-cadherin-adh-1-interaction-a-computational-survey
#10
Mahboobeh Eslami, Navid Nezafat, Sahar Khajeh, Zohreh Mostafavi-Pour, Samaneh Bagheri Novir, Manica Negahdaripour, Younes Ghasemi, Vahid Razban
Due to the considerable role of N-cadherin in cancer metastasis, tumor growth and progression, inhibition of this protein has been highly regarded in recent years. Although ADH-1 has been known as an appropriate inhibitor of N-cadherin in clinical trials, its chemical nature and binding mode with N-cadherin have not been precisely specified yet. Accordingly, in this study quantum mechanics calculations were used to investigate the chemical nature of ADH-1. These calculations clarify the molecular properties of ADH-1 and determine its reactive sites...
January 4, 2018: Journal of Biomolecular Structure & Dynamics
https://www.readbyqxmd.com/read/29300207/stress-distribution-in-splinted-and-unsplinted-implant-supported-maxillary-overdentures-a-3d-finite-element-analysis
#11
Allahyar Geramy, Sareh Habibzadeh
INTRODUCTION: This study was accomplished to assess the biomechanical state of splinting in implant-supported maxillary overdentures. MATERIALS AND METHODS: Two models of maxillary overdentures were designed in SolidWorks 2011. The first model included 4 separate implants and ball abutments, whereas the second one included 4 splinted implants connected with a bar. Evaluation was performed in ANSYS Workbench software with 200 N load applied at the molar-premolar region, bilaterally...
January 3, 2018: Implant Dentistry
https://www.readbyqxmd.com/read/29299382/an-interspecies-comparative-study-of-invasive-electrophysiological-functional-connectivity
#12
Kaitlyn Casimo, Lila H Levinson, Stavros Zanos, C Alexis Gkogkidis, Tonio Ball, Eberhard Fetz, Kurt E Weaver, Jeffrey G Ojemann
Introduction: Resting-state connectivity patterns have been observed in humans and other mammal species, and can be recorded using a variety of different technologies. Functional connectivity has been previously compared between species using resting-state fMRI, but not in electrophysiological studies. Methods: We compared connectivity with implanted electrodes in humans (electrocorticography) to macaques and sheep (microelectrocorticography), which are capable of recording neural data at high frequencies with spatial precision...
December 2017: Brain and Behavior
https://www.readbyqxmd.com/read/29290089/non-interventional-1-year-follow-up-study-of-peri-implant-soft-tissues-following-previous-soft-tissue-augmentation-and-crown-insertion-in-single-tooth-gaps
#13
Samuel Huber, Marco Zeltner, Christoph H F Hämmerle, Ronald E Jung, Daniel S Thoma
AIM: To assess peri-implant soft tissue dimensions at implant sites, previously augmented with a collagen matrix (VCMX) or an autogenous subepithelial connective tissue graft (SCTG), between crown insertion and 1 year. METHODS: Twenty patients with single-tooth implants received soft tissue augmentation prior to abutment connection randomly using VCMX or SCTG. Following abutment connection 3 months later, final reconstructions were fabricated and inserted (baseline)...
December 31, 2017: Journal of Clinical Periodontology
https://www.readbyqxmd.com/read/29289803/application-of-a-rubber-band-with-hooks-on-both-ends-for-vagus-nerve-stimulator-implantation
#14
Hiroshi Hosoyama, Ryosuke Hanaya, Toshiaki Otsubo, Masanori Sato, Yumi Kashida, Sei Sugata, Masaya Katagiri, Koji Iida, Kazunori Arita
BACKGROUND: Vagus nerve stimulation (VNS) is a valuable therapeutic option for many types of drug-resistant epilepsy. Muscle hooks and carotid endarterectomy rings have been used for cervical delamination preceding the implantation of stimulation electrodes. The attachment on both sides of a rubber band of Kamiyama-style hanging needles, as are used for scalp and dural retraction during craniotomy, yields a useful tool for VNS implantation. Here we report our experience with this method...
December 28, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/29286961/regeneration-of-a-completely-transected-sciatic-nerve-with-use-of-a-bioabsorbable-nerve-conduit-filled-with-collagen-with-a-14-year-follow-up-a-case-report
#15
Yuji Inada, Keishichirou Moroi, Shigeru Morimoto, Takamitsu Fujikawa, Hiroshige Tateuchi, Tatsuo Nakamura
CASE: A 65-year-old man with a completely transected left sciatic nerve at the buttock received an implant with a bioabsorbable nerve conduit over a 20-mm gap. The conduit was filled with collagen to facilitate nerve regeneration. At 4 years after implantation, reinnervation potentials were detected in the muscles, and there was sensory recovery in the reinnervated areas. Thereafter, motor and sensory function recovered gradually over a 14-year period. CONCLUSION: Mixed nerve regeneration after conduit-based reconstruction was demonstrated objectively...
October 2017: JBJS Case Connector
https://www.readbyqxmd.com/read/29285671/the-interleukin-33-st2-pathway-is-expressed-in-the-failing-human-heart-and-associated-with-pro-fibrotic-remodeling-of-the-myocardium
#16
Cheyenne C S Tseng, Manon M H Huibers, Joyce van Kuik, Roel A de Weger, Aryan Vink, Nicolaas de Jonge
The interleukin-33 (IL-33)/suppression of tumorigenicity 2 (ST2) pathway is a potential pathophysiological mediator of cardiac fibrosis. Soluble ST2 (sST2) is one of the main isoforms of ST2 with strong prognostic value in cardiac disease. The exact role of sST2 in cardiac fibrosis is unknown. The aim of this study was (1) to investigate myocardial expression of the IL-33/ST2 pathway in relation to myocardial fibrosis in end-stage heart failure patients and (2) to study whether plasma sST2 is associated with histologically determined cardiac fibrosis...
December 28, 2017: Journal of Cardiovascular Translational Research
https://www.readbyqxmd.com/read/29285326/3d-x-ray-microscopic-analysys-on-a-prosthetically-loaded-implant-with-platform-switching-and-conical-connection-a-case-report
#17
M DI Girolamo, L Baggi, P Pirelli, L Pappalardo, G Massei, F Iaculli, G Iezzi, A Piattelli, R Calcaterra
The histological and histomorphometrical examination were the gold standard in the qualitative and quantitative analyses of the peri-implant tissue around the implant. In recent years, the field of microscopy has witnessed a considerable enhancement of the performance of microscopes that have very high resolution performance and allowing very sophisticated analysis even larger than traditional preparations. The possibility to have an affordable analyses of whole implant with the surrounding different tissues (soft and hard tissues) without the traditional pre-treatment necessary for the histological analysis may represent a goal to describe material properties and behaviors or simply to visualize structural details...
July 2017: Oral & Implantology
https://www.readbyqxmd.com/read/29285325/a-new-system-of-implant-abutment-connection-how-to-improve-a-two-piece-implant-system-sealing
#18
F Grecchi, M DI Girolamo, F Cura, V Candotto, F Carinci
Purpose: Implant dentistry has become one of the most successful dentistry techniques for replacing missing teeth. The success rate of implant dentistry is above 80%. However, peri-implantitis is a later complication of implant dentistry that if untreated, can lead to implant loss. One of the hypotized causes of peri-implantis is the bacterial leakage at the level of implant-abutment connection. Bacterial leakage is favored to the presence of a micro gap at the implant-abutment interface, allowing microorganisms to penetrate and colonize the inner part of the implant leading to biofilm accumulation and consequently to peri-implantitis development...
July 2017: Oral & Implantology
https://www.readbyqxmd.com/read/29285090/application-of-silk-fibroin-chitosan-nano-hydroxyapatite-composite-scaffold-in-the-repair-of-rabbit-radial-bone-defect
#19
Peng Ye, Bin Yu, Jiang Deng, Rong-Feng She, Wen-Liang Huang
Silk fibroin (SF), chitosan (CS) and nano-hydroxyapatite (nHA) possess excellent biocompatibility, thus, these were used to construct a SF/CS/nHA composite scaffold. Previously published results identified that this material exhibited satisfactory physical and chemical properties, and therefore qualified as a repair material in bone tissue engineering. The aim of the present study was to investigate the capacity and mechanism of this composite scaffold in repairing bone defects. In total, 45 New Zealand white rabbits were used to model defect in the right radial bone...
December 2017: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/29274159/effect-of-implant-placement-depth-on-the-peri-implant-bone-defect-configurations-in-ligature-induced-peri-implantitis-an-experimental-study-in-dogs
#20
B Huang, L Zhang, L Xu, W Zhu, L Witek, N Tovar, P-G Coelho, H Meng
BACKGROUND: The subcrestal placement of implant platform has been considered a key factor in the preservation of crestal bone, but the influence of implant placement depth on bone remodeling combined with peri-implantitis is not fully understood. The aim of this study was to assess the effect of the crestal or subcrestal placement of implants on peri-implant bone defects of ligature-induced peri-implantitis in dogs. MATERIAL AND METHODS: Eight weeks after tooth extraction in six beagle dogs, two different types of implants (A: OsseoSpeed(TM), Astra, Molndal, Sweden; B: Integra-CP(TM), Bicon, Boston, USA) were placed at either crestal or subcrestal (-1...
January 1, 2018: Medicina Oral, Patología Oral y Cirugía Bucal
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