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https://www.readbyqxmd.com/read/29335903/anterior-cervical-corpectomy-and-fusion-versus-posterior-laminoplasty-for-the-treatment-of-oppressive-myelopathy-owing-to-cervical-ossification-of-posterior-longitudinal-ligament-a-meta-analysis
#1
Rongqing Qin, Xiaoqing Chen, Pin Zhou, Ming Li, Jie Hao, Feng Zhang
PURPOSE: The purpose of this research is to compare the clinical efficacy, postoperative complication and surgical trauma between anterior cervical corpectomy and fusion versus posterior laminoplasty for the treatment of oppressive myelopathy owing to cervical ossification of the posterior longitudinal ligament (OPLL). STUDY DESIGN: Systematic review and meta-analysis. METHODS: An comprehensive search of literature was implemented in three electronic databases (Embase, Pubmed, and the Cochrane library)...
January 15, 2018: European Spine Journal
https://www.readbyqxmd.com/read/29288841/management-of-severe-traumatic-brain-injury-first-24-hours
#2
Thomas Geeraerts, Lionel Velly, Lamine Abdennour, Karim Asehnoune, Gérard Audibert, Pierre Bouzat, Nicolas Bruder, Romain Carrillon, Vincent Cottenceau, François Cotton, Sonia Courtil-Teyssedre, Claire Dahyot-Fizelier, Frédéric Dailler, Jean-Stéphane David, Nicolas Engrand, Dominique Fletcher, Gilles Francony, Laurent Gergelé, Carole Ichai, Etienne Javouhey, Pierre-Etienne Leblanc, Thomas Lieutaud, Philippe Meyer, Sébastien Mirek, Gilles Orliaguet, François Proust, Hervé Quintard, Catherine Ract, Mohamed Srairi, Karim Tazarourte, Bernard Vigué, Jean-François Payen
The latest French Guidelines for the management in the first 24hours of patients with severe traumatic brain injury (TBI) were published in 1998. Due to recent changes (intracerebral monitoring, cerebral perfusion pressure management, treatment of raised intracranial pressure), an update was required. Our objective has been to specify the significant developments since 1998. These guidelines were conducted by a group of experts for the French Society of Anesthesia and Intensive Care Medicine (Société Francaise d'Anesthésie Réanimation (SFAR)) in partnership with the Association de Neuro-Anesthésie-Réanimation de Langue Française (ANARLF), the Société Française de Neurochirurgie (SFN), the Groupe Francophone de Réanimation et d'Urgences Pédiatriques (GFRUP) and the Association des Anesthésistes-Réanimateurs Pédiatriques d'Expression Française (ADARPEF)...
December 27, 2017: Anaesthesia, Critical Care & Pain Medicine
https://www.readbyqxmd.com/read/29282579/accuracy-of-outside-radiologists-reports-of-computed-tomography-exams-of-emergently-transferred-patients
#3
Jeffrey D Robinson, Ken F Linnau, Daniel S Hippe, Kellie L Sheehan, Joel A Gross
PURPOSE: Growing numbers of patient with advanced imaging being transferred to trauma centers has resulted in increased numbers of outside CT scans received at trauma centers. This study examines the degree of agreement between community radiologists' interpretations of the CT scans of transferred patients and trauma center radiologists' reinterpretation. METHODS: All CT scans of emergency transfer patients received over a 1 month period were reviewed by an emergency radiologist...
December 27, 2017: Emergency Radiology
https://www.readbyqxmd.com/read/29282438/management-of-unruptured-traumatic-middle-meningeal-artery-pseudoaneurysms-through-onyx-embolization
#4
Nicolas K Khattar, Andrew C White, Enzo M Fortuny, Rob T Hruska, Robert F James
Traumatic pseudoaneurysms of the middle meningeal artery (MMA) represent less than 1% of all intracranial aneurysms, and occur mostly in association with temporal bone fractures following head trauma. Given the unknown natural history, it is unclear whether they should be treated. We present two cases of MMA pseudoaneurysms discovered during trauma workups. The first patient is a 44-year-old male with severe traumatic brain injury (TBI) following a motor vehicle accident. The patient was found to have two right-sided middle meningeal artery pseudoaneurysms that were treated successfully with Onyx® (Medtronic, Minneapolis, MN) embolization...
October 23, 2017: Curēus
https://www.readbyqxmd.com/read/29175959/disrupted-neuro-glial-metabolic-coupling-after-peripheral-surgery
#5
Teresa Femenía, Alfredo Giménez-Cassina, Simone Codeluppi, Teresa Fernández-Zafra, Yurika Katsu-Jiménez, Niccolò Terrando, Lars I Eriksson, Marta Gómez-Galán
Immune-related events in the periphery can remotely affect brain function, contributing to neurodegenerative processes and cognitive decline. In mice, peripheral surgery induces a systemic inflammatory response associated with changes in hippocampal synaptic plasticity and transient cognitive decline, however the underlying mechanisms remain unknown. Here we investigated the effect of peripheral surgery on neuronal-glial function within hippocampal neuronal circuits of relevance to cognitive processing in male mice at 6, 24, and 72h post-surgery...
November 24, 2017: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
https://www.readbyqxmd.com/read/29174817/-bladder-cancer-in-neurogenic-patients-a-retrospective-study-of-management-and-follow-up
#6
P Ali, C Lefevre, B Perrouin-Verbe, L Le Normand, J Rigaud, O Bouchot, A Levesque, M-A Perrouin-Verbe
INTRODUCTION: The prevalence of bladder cancer (BC) in neurological patients seems to be similar to that of the general population. However, they are more aggressive with a higher rate of muscle-invasive forms and squamous cells carcinomas. The aim of the current study was to report etiologies, management and outcomes of BC in neurological population. MATERIAL AND METHOD: Were enrolled all neurological patients with a BC diagnosed between 2004 and 2017. The following data were retrospectively reported: age, gender, duration of the disease, mode of discovery, histological type, treatment and outcomes...
November 22, 2017: Progrès en Urologie
https://www.readbyqxmd.com/read/29159958/evaluation-of-a-low-risk-mild-traumatic-brain-injury-and-intracranial-hemorrhage-emergency-department-observation-protocol
#7
Brian J Yun, Pierre Borczuk, Lulu Wang, Stephen Dorner, Benjamin A White, Ali S Raja
OBJECTIVES: Among emergency physicians, there is wide variation in admitting practices for patients who suffered a mild traumatic brain injury (TBI) with an intracranial hemorrhage (ICH). The purpose of this study was to evaluate the effects of implementing a protocol in the emergency department (ED) observation unit for patients with mild TBI and ICH. METHODS: This retrospective cohort study was approved by the Institutional Review Board. Study subjects were patients ≥18 years of age with an International Classification of Diseases (ICD) code corresponding to a traumatic IC, and admitted to an ED observation unit (EDOU) of an urban, academic level 1 trauma center between February 1, 2015 and January 31, 2017...
November 20, 2017: Academic Emergency Medicine: Official Journal of the Society for Academic Emergency Medicine
https://www.readbyqxmd.com/read/29143889/beyond-pathologizing-harm-understanding-ptsd-in-the-context-of-war-experience
#8
Patricia Benner, Jodi Halpern, Deborah R Gordon, Catherine Long Popell, Patricia W Kelley
An alternative to objectifying approaches to understanding Post-traumatic Stress Disorder (PTSD) grounded in hermeneutic phenomenology is presented. Nurses who provided care for soldiers injured in the Iraq and Afghanistan wars, and sixty-seven wounded male servicemen in the rehabilitation phase of their recovery were interviewed. PTSD is the one major psychiatric diagnosis where social causation is established, yet PTSD is predominantly viewed in terms of the usual neuro-physiological causal models with traumatic social events viewed as pathogens with dose related effects...
November 16, 2017: Journal of Medical Humanities
https://www.readbyqxmd.com/read/29142631/mortality-and-epidemiology-in-256-cases-of-pediatric-traumatic-brain-injury-korean-neuro-trauma-data-bank-system-kntdbs-2010-2014
#9
Hee-Won Jeong, Seung-Won Choi, Jin-Young Youm, Jeong-Wook Lim, Hyon-Jo Kwon, Shi-Hun Song
Objective: Among pediatric injury, brain injury is a leading cause of death and disability. To improve outcomes, many developed countries built neurotrauma databank (NTDB) system but there was not established nationwide coverage NTDB until 2009 and there have been few studies on pediatric traumatic head injury (THI) patients in Korea. Therefore, we analyzed epidemiology and outcome from the big data of pediatric THI. Methods: We collected data on pediatric patients from 23 university hospitals including 9 regional trauma centers from 2010 to 2014 and analyzed their clinical factors (sex, age, initial Glasgow coma scale, cause and mechanism of head injury, presence of surgery)...
November 2017: Journal of Korean Neurosurgical Society
https://www.readbyqxmd.com/read/29125266/decision-making-in-very-severe-traumatic-brain-injury-glasgow-coma-scale-3-5-a-literature-review-of-acute-neurosurgical-management-of-the-most-severely-threatened-brain-trauma-patients
#10
Jeroen van Dijck, Florence Reith, Inge van Erp, Thomas van Essen, Andrew Maas, Wilco C Peul, Godard de Ruiter
BACKGROUND: Patients presenting with an early GCS score of 3-5 after blunt or penetrating skull-brain assaults are categorized as having sustained a very severe Traumatic Brain Injury (vs-TBI). This category is often overlooked in literature. Impact on patients and families lives however is huge and the question "whether to surgically treat or not" frequently poses a dilemma to treating physicians. Little is known about mortality and outcome, compared to what is known for the group of severe TBI patients (s-TBI) (GCS 3- 8)...
November 10, 2017: Journal of Neurosurgical Sciences
https://www.readbyqxmd.com/read/29098418/bilateral-carotid-cavernous-sinus-fistula-a-case-report-and-review-of-the-literature
#11
REVIEW
Gavin Docherty, Maryam Eslami, Kailun Jiang, Jason S Barton
Carotid cavernous fistula (CCF) is an abnormal vascular shunt from the carotid artery to the cavernous sinus. They are commonly classified based on hemodynamics, etiology or anatomically. Hemodynamic classification refers to whether the fistula is high or low flow. Etiology is commonly secondary to trauma or can occur spontaneously in the setting of aneurysm or medical conditions predisposing to arterial wall defects. Bilateral carotid cavernous fistulas are rare. We present a case of bilateral CCF secondary to trauma...
November 2, 2017: Journal of Neurology
https://www.readbyqxmd.com/read/29095850/lesions-in-deep-gray-nuclei-after-severe-traumatic-brain-injury-predict-neurologic-outcome
#12
Frédéric Clarençon, Éric Bardinet, Jacques Martinerie, Vincent Pelbarg, Nicolas Menjot de Champfleur, Rajiv Gupta, Eléonore Tollard, Gustavo Soto-Ares, Danielle Ibarrola, Emmanuelle Schmitt, Thomas Tourdias, Vincent Degos, Jérome Yelnik, Didier Dormont, Louis Puybasset, Damien Galanaud
PURPOSE: This study evaluates the correlation between injuries to deep gray matter nuclei, as quantitated by lesions in these nuclei on MR T2 Fast Spin Echo (T2 FSE) images, with 6-month neurological outcome after severe traumatic brain injury (TBI). MATERIALS AND METHODS: Ninety-five patients (80 males, mean age = 36.7y) with severe TBI were prospectively enrolled. All patients underwent a MR scan within the 45 days after the trauma that included a T2 FSE acquisition...
2017: PloS One
https://www.readbyqxmd.com/read/29063484/micrornas-in-post-traumatic-stress-disorder
#13
Clara Snijders, Laurence de Nijs, Dewleen G Baker, Richard L Hauger, Daniel van den Hove, Gunter Kenis, Caroline M Nievergelt, Marco P Boks, Eric Vermetten, Fred H Gage, Bart P F Rutten
Post-traumatic stress disorder (PTSD) is a psychiatric disorder that can develop following exposure to or witnessing of a (potentially) threatening event. A critical issue is to pinpoint the (neuro)biological mechanisms underlying the susceptibility to stress-related disorder such as PTSD, which develops in the minority of ~15% of individuals exposed to trauma. Over the last few years, a first wave of epigenetic studies has been performed in an attempt to identify the molecular underpinnings of the long-lasting behavioral and mental effects of trauma exposure...
October 21, 2017: Current Topics in Behavioral Neurosciences
https://www.readbyqxmd.com/read/29039808/a-diagnosis-of-denial-how-mental-health-classification-systems-have-struggled-to-recognise-family-violence-as-a-serious-risk-factor-in-the-development-of-mental-health-issues-for-infants-children-adolescents-and-adults
#14
Wendy Bunston, Candice Franich-Ray, Sara Tatlow
Child and adolescent mental health services (CAMHS) routinely overlook assessing for, and providing treatment to, infants and children living with family violence, despite family violence being declared endemic across the globe. As contemporary neuro-developmental research recognises the harm of being exposed to early relational trauma, key international diagnostic texts such as the DSM-5 and ICD-10 struggle to acknowledge or appreciate the relational complexities inherent in addressing family violence and its impacts during childhood...
October 17, 2017: Brain Sciences
https://www.readbyqxmd.com/read/28988973/comparative-connectomics-mapping-the-inter-individual-variability-of-connections-within-the-regions-of-the-human-brain
#15
Csaba Kerepesi, Balázs Szalkai, Bálint Varga, Vince Grolmusz
The human braingraph, or connectome is a description of the connections of the brain: the nodes of the graph correspond to small areas of the gray matter, and two nodes are connected by an edge if a diffusion MRI-based workflow finds fibers between those brain areas. We have constructed 1015-vertex graphs from the diffusion MRI brain images of 392 human subjects and compared the individual graphs with respect to several different areas of the brain. The inter-individual variability of the graphs within different brain regions was discovered and described...
October 6, 2017: Neuroscience Letters
https://www.readbyqxmd.com/read/28988342/spectrum-of-outcomes-following-traumatic-brain-injury-relationship-between-functional-impairment-and-health-related-quality-of-life
#16
Anastasia Tsyben, Mathew Guilfoyle, Ivan Timofeev, Fahim Anwar, Judith Allanson, Joanne Outtrim, David Menon, Peter Hutchinson, Adel Helmy
BACKGROUND: The outcome following traumatic brain injury (TBI) is heterogeneous and poorly defined and physical disability scales like the extended Glasgow Outcome Score (GOSE) while providing valuation information in terms of broad categorisation of outcome are unlikely to capture the full spectrum of deficits. Quality of life questionnaires such as SF-36 are emerging as potential tools to help characterise factors important to patients' recovery. This study assessed the association between physical disability and subjective health rating...
October 7, 2017: Acta Neurochirurgica
https://www.readbyqxmd.com/read/28969714/pathogenesis-and-potential-relative-risk-factors-of-diabetic-neuropathic-osteoarthropathy
#17
REVIEW
Hong-Mou Zhao, Jia-Yu Diao, Xiao-Jun Liang, Feng Zhang, Ding-Jun Hao
Diabetic neuropathic osteoarthropathy (DNOAP) is an uncommon, but with considerable morbidity and mortality rates, complication of diabetes. The real pathogenesis is still unclear. The two popular theories are the neuro-vascular theory and neuro-traumatic theory. Most theories and pathways focused on the uncontrolled inflammations that resulted in the final common pathway, receptor activator of nuclear factor κβ ligand (RANKL)/osteoprotegerin (OPG) axis, for the decreased bone density in DNOAP with an osteoclast and osteoblast imbalance...
October 2, 2017: Journal of Orthopaedic Surgery and Research
https://www.readbyqxmd.com/read/28876567/a-review-of-presentations-to-the-surgical-research-society-of-southern-africa-and-the-association-of-surgeons-of-south-africa-from-2010-to-2016
#18
S Burger, S van Straten, S Rayne
This paper looks at research done in South Africa from 2010 to 2016. We reviewed a total of 679 abstracts, posters and oral presentations submitted to the SAJS and the ASSA congresses during this time. During this time 21945 patients were investigated with an average of 577,5 patients per study. Each paper had on average 3,5 authors. The most popular topics are trauma (23%), gastrointestinal surgery (18%) and breast (11%). Upcoming topics include: reducing sepsis, global surgery, procedural discussion, infectious diseases (HIV/ TB), post-operative healing, ENT, neuro, plastic surgery, cardiothoracic and paediatric surgery...
September 2017: South African Journal of Surgery. Suid-Afrikaanse Tydskrif Vir Chirurgie
https://www.readbyqxmd.com/read/28865131/quercetin-reduces-neural-tissue-damage-and-promotes-astrocyte-activation-after-spinal-cord-injury-in-rats
#19
Yeyang Wang, Wenjun Li, Mingsen Wang, Chuangxin Lin, Guitao Li, Xiaozhong Zhou, Junnan Luo, Dadi Jin
Spinal cord injury (SCI) is lead to locomotor impairment because of neurological damage after following trauma. Quercetin (Que) has been confirmed have a neuro-protective effect during nerve damage processes. The purpose of this study was to determine the roles of Que in functional recovery, cavity formation, astrocyte activation and nerve regeneration following SCI. Sprague-Dawley rats were randomly divided into 3 groups: Sham group, SCI group and Que + SCI group. A rat model of SCI was made at T10 using the modified Allen's method...
September 2, 2017: Journal of Cellular Biochemistry
https://www.readbyqxmd.com/read/28860515/activation-of-the-peripheral-immune-system-regulates-neuronal-aromatase-in-the-adult-zebra-finch-brain
#20
Alyssa L Pedersen, Cassie J Gould, Colin J Saldanha
Estradiol provision via neural aromatization decreases neuro-inflammation and -degeneration, but almost nothing is known about the interactions between the peripheral immune system and brain aromatase. Given the vulnerability of the CNS we reasoned that brain aromatization may protect circuits from the threats of peripheral infection; perhaps shielding cells that are less resilient from the degeneration associated with peripheral infection or trauma. Lipopolysaccharide (LPS) or vehicle was administered peripherally to adult zebra finches and sickness behavior was recorded 2 or 24 hours later...
August 31, 2017: Scientific Reports
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