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https://www.readbyqxmd.com/read/29756712/traumatic-cataract-surgery-in-pediatric-patients-experience-in-a-site
#1
Verónica Y Burgos-Elías, Ma José Marroquín-Sarti, Martin A Zimmermann-Paiz, Ana Marissa Ordoñez Rivas, Nancy C Quezada-Del Cid
of this study was to determine the characteristics of patients younger than 14 years who underwent traumatic cataract surgery at the Unit of Pediatric Ophthalmology, Strabismus and Neuro-Ophthalmology "Dra. Ana María Illescas Putzeys" of Hospital de Ojos y Oídos "Dr. Rodolfo Robles V." A retrospective, descriptive, and observational study was carried out to review the medical records of patients who underwent cataract surgery between 2010 and 2015. A total of 54 children underwent traumatic cataract surgery; 75% were boys; 68% were in the 6-11-year-old age range...
June 1, 2018: Archivos Argentinos de Pediatría
https://www.readbyqxmd.com/read/29756600/the-development-of-neural-stimulators-a-review-of-preclinical-safety-and-efficacy-studies
#2
Robert K Shepherd, Joel Villalobos, Owen Burns, David Nayagam
OBJECTIVE: Given the rapid expansion of the field of neural stimulation and the rigorous regulatory approval requirements required before these devices can be applied clinically, it is important that there is clarity around conducting preclinical safety and efficacy studies required for the development of this technology. APPROACH: The present review examines basic design principles associated with the development of a safe neural stimulator and describes the suite of preclinical safety studies that need to be considered when taking a device to clinical trial...
May 14, 2018: Journal of Neural Engineering
https://www.readbyqxmd.com/read/29737185/neuro-reciprocity-and-vicarious-trauma-in-psychiatrists
#3
Sophie Isobel, Gavin Angus-Leppan
OBJECTIVES: This paper aims to briefly overview the processes of neuro-reciprocity relevant to vicarious traumatization of psychiatrists through their clinical roles. CONCLUSIONS: High rates of trauma in mental health service users, understanding of the effects of trauma on the brain and mechanisms of neuro-reciprocity in empathic attunement suggest that psychiatrists are at high risk of vicarious trauma. Preventing vicarious trauma at an organizational level through trauma-informed approaches is of paramount importance...
May 1, 2018: Australasian Psychiatry: Bulletin of Royal Australian and New Zealand College of Psychiatrists
https://www.readbyqxmd.com/read/29682085/prostaglandin-e-2-produced-by-alginate-encapsulated-mesenchymal-stromal-cells-modulates-the-astrocyte-inflammatory-response
#4
Elizabeth C Stucky, Joshua Erndt-Marino, Rene S Schloss, Martin L Yarmush, David I Shreiber
Astroglia are well known for their role in propagating secondary injury following brain trauma. Modulation of this injury cascade, including inflammation, is essential to repair and recovery. Mesenchymal stromal cells (MSCs) have been demonstrated as trophic mediators in several models of secondary CNS injury, however, there has been varied success with the use of direct implantation due to a failure to persist at the injury site. To achieve sustained therapeutic benefit, we have encapsulated MSCs in alginate microspheres and evaluated the ability of these encapsulated MSCs to attenuate neuro-inflammation...
June 2017: Nano LIFE
https://www.readbyqxmd.com/read/29656802/impact-on-the-brain-of-the-inflammatory-response-to-surgery
#5
REVIEW
Sarah Saxena, Mervyn Maze
The brain is both the orchestrator as well as the target of the innate immune system's response to the aseptic trauma of surgery. When trauma-induced inflammation is not appropriately regulated persistent neuro-inflammation interferes with the synaptic plasticity that underlies the learning and memory aspects of cognition. The complications that ensue, include postoperative delirium (POD) and postoperative cognitive dysfunction (POCD) at two poles of a constellation that is now termed perioperative neurocognitive disorders...
April 2018: La Presse Médicale
https://www.readbyqxmd.com/read/29623601/effects-of-minimally-invasive-approaches-on-chronic-subdural-hematoma-by-novel-yl-1-puncture-needle-and-burr-hole-methods
#6
Min Xu, Wen-Hua Wang, Sheng-Qiang Zhu, Wei-Guo Tan, Xue-Gang Jin, Wei Lu, Long Chen
The objective of this study is to investigate effects of minimally invasive approaches on outcome of chronic subdural hematoma (CSDH) by novel YL-1 puncture needle and burr-hole methods. A retrospective analysis was performed in 158 hospitalized CSDH patients from January, 2013 to December, 2017 in Kunshan Hospital of Traditional Chinese Medicine. Patients' gender, age, history of trauma, volume of hematoma, hematoma location, application of urokinase, surgical approach, the operation time, hospitalized time, and CT scans 3 months after discharge were recorded...
April 5, 2018: Acta Neurologica Belgica
https://www.readbyqxmd.com/read/29542039/in-major-affective-disorders-early-life-trauma-predict-increased-nitro-oxidative-stress-lipid-peroxidation-and-protein-oxidation-and-recurrence-of-major-affective-disorders-suicidal-behaviors-and-a-lowered-quality-of-life
#7
Juliana Brum Moraes, Michael Maes, Chutima Roomruangwong, Kamila Landucci Bonifacio, Decio Sabbatini Barbosa, Heber Odebrecht Vargas, George Anderson, Marta Kubera, Andre F Carvalho, Sandra Odebrecht Vargas Nunes
Early life trauma (ELT) may increase the risk towards bipolar disorder (BD) and major depression (MDD), disorders associated with activated neuro-oxidative and neuro-nitrosative stress (O&NS) pathways. It has remained elusive whether ELTs are associated with O&NS and which ELTs are associated with distinct affective disorder phenotypes. This case-control study examined patients with BD (n = 68) and MDD (n = 37) and healthy controls (n = 66). The Child Trauma Questionnaire (CTQ) was used to assess specific ELT...
March 14, 2018: Metabolic Brain Disease
https://www.readbyqxmd.com/read/29538792/non-psychiatric-nurses-perceived-self-efficacy-after-an-educational-intervention-on-suicide-prevention-and-care
#8
Ellen W Blair, Jyoti Chhabra, Cynthia Belonick, Maria Tackett
Potential for suicide risk can be a safety concern for patients in all health care settings. Inadequate training of nurses in suicide assessment and prevention is a serious patient safety concern. A non-randomized pre-/postintervention research design was used to measure the effects of education on non-psychiatric nurses' perceived self-efficacy in assessment and inquiry about suicide risk and in implementing suicide prevention strategies. The intervention was an educational module about suicide prevention and care delivered to non-psychiatric nurses employed on a neuro-trauma unit in an acute care urban hospital setting...
March 14, 2018: Journal of Psychosocial Nursing and Mental Health Services
https://www.readbyqxmd.com/read/29485295/-five-layer-gasket-seal-watertight-closure-for-reconstruction-of-the-skull-base-in-complex-bilateral-traumatic-intraorbital-meningoencephaloceles-a-case-report-and-literature-review
#9
Dan Zhao, Shanwei Tao, Dewei Zhang, Mengyang Qin, Yijun Bao, Anhua Wu
PURPOSE: Traumatic meningoencephalocele primarily occurs as a rare but complex complication of cranial base and orbital roof fractures. Traumatic intraorbital meningoencephalocele, which is rare and easily overlooked, can be life-threatening since cephalomeningitis occurs due to cerebrospinal fluid (CSF) leakage. It is obscure for the operative indications or standard surgical methods of traumatic meningoencephaloceles since the combined intricate craniofacial and basal fractures, brain injury, and CSF leak may exist...
2018: Brain Injury: [BI]
https://www.readbyqxmd.com/read/29477026/a-case-series-of-closed-head-trauma-with-pituitary-stalk-disruption-resulting-in-hypopituitarism
#10
Khuram Khan, Saqib Saeed, Alexius Ramcharan, Sanjiv Gray
INTRODUCTION: Traumatic brain injury (TBI) is one of the main causes of morbidity and mortality in young trauma patients with resultant multi-organ effects. Hypopituitarism following TBI can be debilitating and life threatening. TBI which causes hypopituitarism may be characterized by a single head injury, such as from a motor vehicle accident, or by chronic repetitive head trauma, as seen in combative supports including boxing, kick-boxing, and football. In the majority of cases, a diagnosis of hypopituitarism can be entirely missed resulting in severe neuro-endocrine dysfunction...
2018: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/29404750/acute-limb-ischemia-secondary-to-native-artery-occlusion-results-of-a-contemporary-case-series
#11
Nuria Seguí, Carlos Ruiz-Carmona, Alina Velescu, Eduardo Mateos, Roberto Elosua, Albert Clará
BACKGROUND: The treatment of acute limb ischemia (ALI) has barely changed over the last years. However, the progressive implementation of anticoagulants, antiplatelet agents or statins within the population might have modified the profile and prognosis of patients suffering an ALI. The aim of this study was to evaluate the current results of the management of ALI secondary to a native artery occlusion. METHODS: Retrospective study of 220 consecutive patients (mean age 78 years; 49% male) was conducted between 2007 and 2015...
February 5, 2018: World Journal of Surgery
https://www.readbyqxmd.com/read/29394252/tau-accumulations-in-the-brains-of-woodpeckers
#12
George Farah, Donald Siwek, Peter Cummings
Woodpeckers experience forces up to 1200-1400 g while pecking. It is assumed due to evolutionary adaptations, the woodpecker is immune to brain injury. This assumption has led to the use of the woodpecker as a model in the development of sports safety equipment such as football helmets. However, it is unknown at this time if the woodpecker brain develops neuro-trauma in relation to the high g-forces experienced during pecking. The brains of 10 ethanol preserved woodpeckers and 5 ethanol preserved red-winged black bird experimental controls were examined using Gallyas silver stain and anti-phospho-tau...
2018: PloS One
https://www.readbyqxmd.com/read/29370308/semaphorin3a-induces-nerve-regeneration-in-the-adult-cornea-a-switch-from-its-repulsive-role-in-development
#13
Min Zhang, Qiang Zhou, Yuncin Luo, Tara Nguyen, Mark I Rosenblatt, Victor H Guaiquil
The peripheral sensory nerves that innervate the cornea can be easily damaged by trauma, surgery, infection or diabetes. Several growth factors and axon guidance molecules, such as Semaphorin3A (Sema3A) are upregulated upon cornea injury. Nerves can regenerate after injury but do not recover their original density and patterning. Sema3A is a well known axon guidance and growth cone repellent protein during development, however its role in adult cornea nerve regeneration remains undetermined. Here we investigated the neuro-regenerative potential of Sema3A on adult peripheral nervous system neurons such as those that innervate the cornea...
2018: PloS One
https://www.readbyqxmd.com/read/29335903/anterior-cervical-corpectomy-and-fusion-versus-posterior-laminoplasty-for-the-treatment-of-oppressive-myelopathy-owing-to-cervical-ossification-of-posterior-longitudinal-ligament-a-meta-analysis
#14
Rongqing Qin, Xiaoqing Chen, Pin Zhou, Ming Li, Jie Hao, Feng Zhang
PURPOSE: The purpose of this research is to compare the clinical efficacy, postoperative complication and surgical trauma between anterior cervical corpectomy and fusion versus posterior laminoplasty for the treatment of oppressive myelopathy owing to cervical ossification of the posterior longitudinal ligament (OPLL). STUDY DESIGN: Systematic review and meta-analysis. METHODS: An comprehensive search of literature was implemented in three electronic databases (Embase, Pubmed, and the Cochrane library)...
January 15, 2018: European Spine Journal
https://www.readbyqxmd.com/read/29288841/management-of-severe-traumatic-brain-injury-first-24hours
#15
Thomas Geeraerts, Lionel Velly, Lamine Abdennour, Karim Asehnoune, Gérard Audibert, Pierre Bouzat, Nicolas Bruder, Romain Carrillon, Vincent Cottenceau, François Cotton, Sonia Courtil-Teyssedre, Claire Dahyot-Fizelier, Frédéric Dailler, Jean-Stéphane David, Nicolas Engrand, Dominique Fletcher, Gilles Francony, Laurent Gergelé, Carole Ichai, Étienne Javouhey, Pierre-Etienne Leblanc, Thomas Lieutaud, Philippe Meyer, Sébastien Mirek, Gilles Orliaguet, François Proust, Hervé Quintard, Catherine Ract, Mohamed Srairi, Karim Tazarourte, Bernard Vigué, Jean-François Payen
The latest French Guidelines for the management in the first 24hours of patients with severe traumatic brain injury (TBI) were published in 1998. Due to recent changes (intracerebral monitoring, cerebral perfusion pressure management, treatment of raised intracranial pressure), an update was required. Our objective has been to specify the significant developments since 1998. These guidelines were conducted by a group of experts for the French Society of Anesthesia and Intensive Care Medicine (Société francaise d'anesthésie et de réanimation [SFAR]) in partnership with the Association de neuro-anesthésie-réanimation de langue française (ANARLF), The French Society of Emergency Medicine (Société française de médecine d'urgence (SFMU), the Société française de neurochirurgie (SFN), the Groupe francophone de réanimation et d'urgences pédiatriques (GFRUP) and the Association des anesthésistes-réanimateurs pédiatriques d'expression française (ADARPEF)...
April 2018: Anaesthesia, Critical Care & Pain Medicine
https://www.readbyqxmd.com/read/29282579/accuracy-of-outside-radiologists-reports-of-computed-tomography-exams-of-emergently-transferred-patients
#16
Jeffrey D Robinson, Ken F Linnau, Daniel S Hippe, Kellie L Sheehan, Joel A Gross
PURPOSE: Growing numbers of patient with advanced imaging being transferred to trauma centers has resulted in increased numbers of outside CT scans received at trauma centers. This study examines the degree of agreement between community radiologists' interpretations of the CT scans of transferred patients and trauma center radiologists' reinterpretation. METHODS: All CT scans of emergency transfer patients received over a 1 month period were reviewed by an emergency radiologist...
April 2018: Emergency Radiology
https://www.readbyqxmd.com/read/29282438/management-of-unruptured-traumatic-middle-meningeal-artery-pseudoaneurysms-through-onyx-embolization
#17
Nicolas K Khattar, Andrew C White, Enzo M Fortuny, Rob T Hruska, Robert F James
Traumatic pseudoaneurysms of the middle meningeal artery (MMA) represent less than 1% of all intracranial aneurysms, and occur mostly in association with temporal bone fractures following head trauma. Given the unknown natural history, it is unclear whether they should be treated. We present two cases of MMA pseudoaneurysms discovered during trauma workups. The first patient is a 44-year-old male with severe traumatic brain injury (TBI) following a motor vehicle accident. The patient was found to have two right-sided middle meningeal artery pseudoaneurysms that were treated successfully with Onyx® (Medtronic, Minneapolis, MN) embolization...
October 23, 2017: Curēus
https://www.readbyqxmd.com/read/29175959/disrupted-neuroglial-metabolic-coupling-after-peripheral-surgery
#18
Teresa Femenía, Alfredo Giménez-Cassina, Simone Codeluppi, Teresa Fernández-Zafra, Yurika Katsu-Jiménez, Niccolò Terrando, Lars I Eriksson, Marta Gómez-Galán
Immune-related events in the periphery can remotely affect brain function, contributing to neurodegenerative processes and cognitive decline. In mice, peripheral surgery induces a systemic inflammatory response associated with changes in hippocampal synaptic plasticity and transient cognitive decline, however, the underlying mechanisms remain unknown. Here we investigated the effect of peripheral surgery on neuronal-glial function within hippocampal neuronal circuits of relevance to cognitive processing in male mice at 6, 24, and 72 h postsurgery...
January 10, 2018: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
https://www.readbyqxmd.com/read/29174817/-bladder-cancer-in-neurogenic-patients-a-retrospective-study-of-management-and-follow-up
#19
P Ali, C Lefevre, B Perrouin-Verbe, L Le Normand, J Rigaud, O Bouchot, A Levesque, M-A Perrouin-Verbe
INTRODUCTION: The prevalence of bladder cancer (BC) in neurological patients seems to be similar to that of the general population. However, they are more aggressive with a higher rate of muscle-invasive forms and squamous cells carcinomas. The aim of the current study was to report etiologies, management and outcomes of BC in neurological population. MATERIAL AND METHOD: Were enrolled all neurological patients with a BC diagnosed between 2004 and 2017. The following data were retrospectively reported: age, gender, duration of the disease, mode of discovery, histological type, treatment and outcomes...
March 2018: Progrès en Urologie
https://www.readbyqxmd.com/read/29159958/evaluation-of-a-low-risk-mild-traumatic-brain-injury-and-intracranial-hemorrhage-emergency-department-observation-protocol
#20
Brian J Yun, Pierre Borczuk, Lulu Wang, Stephen Dorner, Benjamin A White, Ali S Raja
OBJECTIVES: Among emergency physicians, there is wide variation in admitting practices for patients who suffered a mild traumatic brain injury (TBI) with an intracranial hemorrhage (ICH). The purpose of this study was to evaluate the effects of implementing a protocol in the emergency department (ED) observation unit for patients with mild TBI and ICH. METHODS: This retrospective cohort study was approved by the institutional review board. Study subjects were patients ≥ 18 years of age with an International Classification of Diseases code corresponding to a traumatic ICH and admitted to an ED observation unit (EDOU) of an urban, academic Level I trauma center between February 1, 2015, and January 31, 2017...
November 20, 2017: Academic Emergency Medicine: Official Journal of the Society for Academic Emergency Medicine
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