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Neuro trauma

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https://www.readbyqxmd.com/read/28706764/neuroradiological-endovascular-intervention-for-diplopia-in-a-case-of-aneurysmal-aberrant-regeneration-of-the-third-nerve
#1
Anupam C A Rao, Saumil A Shah, Benjamin W C Sim, Steven T H Yun, Neeranjali S Jain, Yashar Kalani, Ian C Francis
Aberrant regeneration of the third nerve occurs as a result of synkinetic 'miswiring' of the third nerve following its injury, such as in third cranial nerve palsy due to tumor, trauma, or aneurysm. The case presented is an elderly woman with new vertical diplopia, which led to a diagnosis of a third cranial nerve palsy, thought to be caused by a 5 mm blister aneurysm of the posterior communicating artery. However, neuro-ophthalmological evaluation diagnosed aberrant regeneration of the third nerve, with the cause of her new vertical diplopia being an ipsilateral fourth nerve palsy...
June 12, 2017: Curēus
https://www.readbyqxmd.com/read/28704652/environmental-stress-causes-lethal-neuro-trauma-during-asymptomatic-viral-infections
#2
Jonathan Chow, Zsuzsa Márka, Imre Bartos, Szabolcs Márka, Jonathan C Kagan
Asymptomatic infections often proceed undetected, yet can still prime the host to be sensitive to secondary environmental stress. While the mechanisms underlying disease caused by asymptomatic infections are unknown, it is believed that productive pathogen replication is required. We report that the environmental stress of carbon dioxide (CO2) anesthesia converts an asymptomatic rhabdovirus infection in Drosophila to one that is lethal. This lethality results from a pool of infectious virus in glial cells and is regulated by the antiviral RNAi pathway of the host...
July 12, 2017: Cell Host & Microbe
https://www.readbyqxmd.com/read/28699144/palliative-care-needs-assessment-in-the-neuro-icu-effect-on-family
#3
Claire J Creutzfeldt, Marina G Hanna, C Sherry Cheever, Abhijit V Lele, Charles Spiekerman, Ruth A Engelberg, J Randall Curtis
BACKGROUND: Examine the association of a daily palliative care needs checklist on outcomes for family members of patients discharged from the neurosciences intensive care unit (neuro-ICU). METHODS: We conducted a prospective, longitudinal cohort study in a single, thirty-bed neuro-ICU in a regional comprehensive stroke and level 1 trauma center. One of two neuro-ICU services that admit patients to the same ICU on alternating days used a palliative care needs checklist during morning work rounds...
July 11, 2017: Neurocritical Care
https://www.readbyqxmd.com/read/28574329/spinal-epidural-hematomas-personal-experience-and-literature-review-of-more-than-1000-cases
#4
REVIEW
Maurizio Domenicucci, Cristina Mancarella, Giorgio Santoro, Demo Eugenio Dugoni, Alessandro Ramieri, Maria Felice Arezzo, Paolo Missori
OBJECTIVE The goal of this study was to identify factors that contribute to the formation of acute spinal epidural hematoma (SEH) by correlating etiology, age, site, clinical status, and treatment with immediate results and long-term outcomes. METHODS The authors reviewed their series of 15 patients who had been treated for SEH between 1996 and 2012. In addition, the authors reviewed the relevant international literature from 1869 (when SEH was first described) to 2012, collecting a total of 1010 cases. Statistical analysis was performed in 959 (95%) cases that were considered valid for assessing the incidence of age, sex, site, and clinical status at admission, correlating each of these parameters with the treatment results...
August 2017: Journal of Neurosurgery. Spine
https://www.readbyqxmd.com/read/28567167/nurse-competence-on-physiologic-monitors-use-toward-eliminating-alarm-fatigue-in-intensive-care-units
#5
Azizeh K Sowan, Ana G Vera, Elma I Fonseca, Charles C Reed, Albert F Tarriela, Andrea E Berndt
BACKGROUND: Studies on nurse competence on alarm management are a few and tend to be focused on limited skills. In response to Phase II of implementing the National Patient Safety Goal on clinical alarm systems safety, this study assessed nurses' perceived competence on physiologic monitors use in intensive care units (ICUs) and developed and validated a tool for this purpose. METHODS: This descriptive study took place in a Magnet hospital in a Southwestern state of the U...
2017: Open Medical Informatics Journal
https://www.readbyqxmd.com/read/28530340/-can-post-traumatic-stress-disorder-be-prevented-with-glucocorticoids
#6
REVIEW
Hagit Cohen, Zeev Kaplan, Joseph Zohar
Glucocorticoids (GCs) play a major role in orchestrating the complex physiological and behavioral reactions essential for the maintenance of homeostasis. These compounds enable the organism to prepare for, respond to and cope with the acute demands of physical and emotional stressors. The appropriate GC release, commensurate with stressor severity, enables the body to properly contain stress responses so as to promote recovery by rapidly restoring homeostasis. Indeed, inadequate GC release following stress not only delays recovery by disrupting biological homeostasis in the short run but can also interfere with the processing or interpretation of stressful information that results in long-term disruptions in memory integration...
December 2016: Harefuah
https://www.readbyqxmd.com/read/28504334/advances-in-functional-brain-imaging-technology-and-developmental-neuro-psychology-their-applications-in-the-jungian-analytic-domain
#7
Leon Petchkovsky
Analytical psychology shares with many other psychotherapies the important task of repairing the consequences of developmental trauma. The majority of analytic patients come from compromised early developmental backgrounds: they may have experienced neglect, abuse, or failures of empathic resonance from their carers. Functional brain imagery techniques including Quantitative Electroencephalogram (QEEG), and functional Magnetic Resonance Imagery (fMRI), allow us to track mental processes in ways beyond verbal reportage and introspection...
June 2017: Journal of Analytical Psychology
https://www.readbyqxmd.com/read/28479469/vascular-injury-due-to-humerus-fracture-in-pediatric-age-when-the-treatment-is-mandatory
#8
Simone Salvati, Alberto Maria Settembrini, Daniele Bissacco, Raffaello Dallatana, Daniela Mazzaccaro, Cornelio Crippa, Pietro Romano, Piergiorgio Settembrini
BACKGROUND: Pink pulseless hand syndrome is a rare condition of vascular injury due to distal humerus fracture. It is characterized by radial and ulnar pulselessness in a complex of good hand perfusion which can remain pink and warm. The management and treatment of this condition is still very debated. METHODS: We report four cases of arm traumas which occurred in pediatric patients. In all cases, after the fixation of the fracture by the orthopedic surgeon, the clinical evaluation and duplex ultrasound demonstrated the so called "pink pulseless hand syndrome"...
May 4, 2017: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/28457689/development-of-a-neuro-early-mobilization-protocol-for-use-in-a-neuroscience-intensive-care-unit
#9
Megan A Brissie, Meg Zomorodi, Sharmila Soares-Sardinha, J Dedrick Jordan
OBJECTIVE: Through evaluation of the literature and working with a team of multidisciplinary healthcare providers, our objective was to refine an interprofessional Neuro Early Mobilization Protocol for complex patients in the Neuroscience Intensive Care Unit. RESEARCH METHODOLOGY: Using the literature as a guide, key stakeholders, from multiple professions, designed and refined a Neuro Early Mobilization Protocol. SETTING: This project took place at a large academic medical center in the southeast United States classified as both a Level I Trauma Center and Comprehensive Stroke Center...
April 27, 2017: Intensive & Critical Care Nursing: the Official Journal of the British Association of Critical Care Nurses
https://www.readbyqxmd.com/read/28396009/molecular-mechanisms-of-brain-derived-neurotrophic-factor-in-neuro-protection-recent-developments
#10
REVIEW
Hailin Zhao, Azeem Alam, Chun-Yin San, Shiori Eguchi, Qian Chen, Qingquan Lian, Daqing Ma
Neuronal cell injury, as a consequence of acute or chronic neurological trauma, is a significant cause of mortality around the world. On a molecular level, the condition is characterized by widespread cell death and poor regeneration, which can result in severe morbidity in survivors. Potential therapeutics are of major interest, with a promising candidate being brain-derived neurotrophic factor (BDNF), a ubiquitous agent in the brain which has been associated with neural development and may facilitate protective and regenerative effects following injury...
April 7, 2017: Brain Research
https://www.readbyqxmd.com/read/28394020/-we-will-never-be-normal-the-experience-of-discovering-a-partner-has-autism-spectrum-disorder
#11
Laura F Lewis
Online forums and lay literature suggest that partners of individuals with Autism Spectrum Disorder (ASD) experience depression, distress, and trauma in their everyday lives, exacerbated during the time surrounding diagnosis. In this content analysis, 29 participants were provided with an online open-ended statement asking them to describe in writing their experiences of discovering that their partners had ASD during their relationships. Six themes emerged, including: facing unique challenges within relationships; insisting partners seek diagnosis; initial shock and relief; losing hope for normalcy; making accommodations within relationships; and wishing for professional support...
April 10, 2017: Journal of Marital and Family Therapy
https://www.readbyqxmd.com/read/28284228/interactive-wearable-systems-for-upper-body-rehabilitation-a-systematic-review
#12
REVIEW
Qi Wang, Panos Markopoulos, Bin Yu, Wei Chen, Annick Timmermans
BACKGROUND: The development of interactive rehabilitation technologies which rely on wearable-sensing for upper body rehabilitation is attracting increasing research interest. This paper reviews related research with the aim: 1) To inventory and classify interactive wearable systems for movement and posture monitoring during upper body rehabilitation, regarding the sensing technology, system measurements and feedback conditions; 2) To gauge the wearability of the wearable systems; 3) To inventory the availability of clinical evidence supporting the effectiveness of related technologies...
March 11, 2017: Journal of Neuroengineering and Rehabilitation
https://www.readbyqxmd.com/read/28281921/lateralization-of-neurobiological-response-in-adolescents-with-post-traumatic-stress-disorder-related-to-severe-childhood-sexual-abuse-the-tri-modal-reaction-t-mr-model-of-protection
#13
Tuba Mutluer, Vedat Şar, Çiğdem Kose-Demiray, Harun Arslan, Sibel Tamer, Serap Inal, Anıl Ş Kaçar
This study inquires into neurobiological response to stress and its clinical correlates among adolescents with post-traumatic stress disorder (PTSD). Structural magnetic resonance imaging (MRI) measures of cerebral anatomy were carried out on 23 female adolescents with PTSD related to severe childhood sexual abuse and 21 matched healthy controls. Clinician Administered PTSD Scale for Children and Adolescents, Adolescent Dissociative Experiences Scale, Childhood Trauma Questionnaire, Schedule for Affective Disorders and Schizophrenia for School Age Children, Beck Depression Scale, and a set of neuro-cognitive tests were administered to all participants...
March 10, 2017: Journal of Trauma & Dissociation
https://www.readbyqxmd.com/read/28225527/neuro-trauma-or-med-surg-intensive-care-unit-does-it-matter-where-multiple-injuries-patients-with-traumatic-brain-injury-are-admitted-secondary-analysis-of-the-american-association-for-the-surgery-of-trauma-multi-institutional-trials-committee-decompressive
#14
MULTICENTER STUDY
Sarah Lombardo, Thomas Scalea, Jason Sperry, Raul Coimbra, Gary Vercruysse, Toby Enniss, Gregory J Jurkovich, Raminder Nirula
INTRODUCTION: Patients with nontraumatic acute intracranial pathology benefit from neurointensivist care. Similarly, trauma patients with and without traumatic brain injury (TBI) fare better when treated by a dedicated trauma team. No study has yet evaluated the role of specialized neurocritical (NICU) and trauma intensive care units (TICU) in the management of TBI patients, and it remains unclear which TBI patients are best served in NICU, TICU, or general (Med/Surg) ICU. METHODS: This study is a secondary analysis of The American Association for the Surgery of Trauma Multi-Institutional Trials Committee (AAST-MITC) decompressive craniectomy study...
March 2017: Journal of Trauma and Acute Care Surgery
https://www.readbyqxmd.com/read/28217399/delayed-and-isolated-oculomotor-nerve-palsy-following-minor-head-trauma
#15
Yu Nakagawa, Masahiro Toda, Shunsuke Shibao, Kazunari Yoshida
BACKGROUND: The purpose of this study was to consider the mechanism of isolated oculomotor nerve palsy after minor head trauma. CASE DESCRIPTION: We report a rare case of delayed and isolated oculomotor nerve palsy following minor head trauma. A 19-year-old boy complained of double vision 1 day after a minor head trauma. Neuro-ophthalmic examination showed isolated left oculomotor nerve palsy. Computed tomography and magnetic resonance imaging examination revealed no abnormal findings and steroid therapy was administered for a week...
2017: Surgical Neurology International
https://www.readbyqxmd.com/read/28212927/patients-with-chronic-dizziness-following-traumatic-head-injury-typically-have-multiple-diagnoses-involving-combined-peripheral-and-central-vestibular-dysfunction
#16
Q Arshad, R E Roberts, H Ahmad, R Lobo, M Patel, T Ham, D J Sharp, B M Seemungal
OBJECTIVE: We hypothesised that chronic vestibular symptoms (CVS) of imbalance and dizziness post-traumatic head injury (THI) may relate to: (i) the occurrence of multiple simultaneous vestibular diagnoses including both peripheral and central vestibular dysfunction in individual patients increasing the chance of missed diagnoses and suboptimal treatment; (ii) an impaired response to vestibular rehabilitation since the central mechanisms that mediate rehabilitation related brain plasticity may themselves be disrupted...
April 2017: Clinical Neurology and Neurosurgery
https://www.readbyqxmd.com/read/28192386/spectrum-of-magnetic-resonance-imaging-features-in-unilateral-optic-tract-dysfunction
#17
Kristopher M Kowal, Francisco F Rivas Rodriguez, Ashok Srinivasan, Jonathan D Trobe
BACKGROUND: Optic tract dysfunction may be the predominant or only clinical manifestation of an intracranial disorder including mass legion, ischemic infarct, inflammatory disease, and trauma. Documentation of the neuroimaging features of these lesions is limited to reports mostly published before the availability of MRI. This study was undertaken to document the spectrum of MRI features in patients presenting with optic tract dysfunction. METHODS: A retrospective study from 2004 to 2015 at a single tertiary care neuro-ophthalmology service of 24 patients who had unilateral optic tract dysfunction defined by a homonymous hemianopia and a relative afferent pupil defect that could not be attributed to optic neuropathy or retinopathy...
March 2017: Journal of Neuro-ophthalmology: the Official Journal of the North American Neuro-Ophthalmology Society
https://www.readbyqxmd.com/read/28180120/effects-of-a-sensory-stimulation-by-nurses-and-families-on-level-of-cognitive-function-and-basic-cognitive-sensory-recovery-of-comatose-patients-with-severe-traumatic-brain-injury-a-randomized-control-trial
#18
Marzieh Moattari, Fatemeh Alizadeh Shirazi, Nasrin Sharifi, Najaf Zareh
BACKGROUND: Several lines of evidence suggest that early sensory stimulation and regular family visiting programs are potential nursing interventions to improve the outcomes of head injured comatose patients. However, little is known about the impacts of family involvement in providing sensory stimulation. OBJECTIVES: To determine the effects of a sensory stimulation program conducted by nurses and families on the consciousness, level of cognitive function, and basic cognitive sensory recovery of head injury comatose patients...
September 2016: Trauma Monthly
https://www.readbyqxmd.com/read/28158149/a-systematic-review-on-the-prevalence-etiology-and-pathophysiology-of-intrinsic-pain-in-dermal-scar-tissue
#19
REVIEW
Eveline Bijlard, Lisa Uiterwaal, Casimir A E Kouwenberg, Marc A M Mureau, Steven E R Hovius, Frank J P M Huygen
BACKGROUND: Scars can cause pain, even without symptoms of underlying nerve damage. A lack of knowledge on intrinsic scar pain hampers effective treatment of these complaints. OBJECTIVE: Aggregate current knowledge on the prevalence, etiology, and pathophysiology of intrinsic pain in dermal scars. STUDY DESIGN: Systematic review. SETTING: University Medical Center. METHODS: We searched the Embase, Medline, Cochrane central, CINAHL, Web-of-Science, and Pubmed databases with search terms: scar, skin, pain, and etiology/pathology, adding all synonyms of these terms...
February 2017: Pain Physician
https://www.readbyqxmd.com/read/28095731/n-palmitoylethanolamine-oxazoline-pea-oxa-as-a-new-therapeutic-strategy-to-control-neuroinflammation-neuroprotective-effects-in-experimental-models-of-spinal-cord-and-brain-injury
#20
Daniela Impellizzeri, Marika Cordaro, Giuseppe Bruschetta, Rosalba Siracusa, Rosalia Crupi, Emanuela Esposito, Salvatore Cuzzocrea
Modulation of N-acylethanolamine-hydrolyzing acid amidase (NAAA) represents a potential alternative strategy in the treatment of neuroinflammation. Recent studies showed that pharmacological modulation of NAAA could be achieved with the oxazoline of palmitoylethanolamide (PEA) (PEA-OXA). The aim of this study was to evaluate the neuroprotective effects of PEA-OXA in the secondary neuro-inflammatory events induced by spinal and brain trauma in mice. Animals were subjected to spinal cord and brain injury models and PEA-OXA (10 mg/kg) administered both intraperitoneally and orally 1 h and 6 h after trauma...
January 17, 2017: Journal of Neurotrauma
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