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https://www.readbyqxmd.com/read/28530340/-can-post-traumatic-stress-disorder-be-prevented-with-glucocorticoids
#1
REVIEW
Hagit Cohen, Zeev Kaplan, Joseph Zohar
Glucocorticoids (GCs) play a major role in orchestrating the complex physiological and behavioral reactions essential for the maintenance of homeostasis. These compounds enable the organism to prepare for, respond to and cope with the acute demands of physical and emotional stressors. The appropriate GC release, commensurate with stressor severity, enables the body to properly contain stress responses so as to promote recovery by rapidly restoring homeostasis. Indeed, inadequate GC release following stress not only delays recovery by disrupting biological homeostasis in the short run but can also interfere with the processing or interpretation of stressful information that results in long-term disruptions in memory integration...
December 2016: Harefuah
https://www.readbyqxmd.com/read/28504334/advances-in-functional-brain-imaging-technology-and-developmental-neuro-psychology-their-applications-in-the-jungian-analytic-domain
#2
Leon Petchkovsky
Analytical psychology shares with many other psychotherapies the important task of repairing the consequences of developmental trauma. The majority of analytic patients come from compromised early developmental backgrounds: they may have experienced neglect, abuse, or failures of empathic resonance from their carers. Functional brain imagery techniques including Quantitative Electroencephalogram (QEEG), and functional Magnetic Resonance Imagery (fMRI), allow us to track mental processes in ways beyond verbal reportage and introspection...
June 2017: Journal of Analytical Psychology
https://www.readbyqxmd.com/read/28479469/vascular-injury-due-to-humerus-fracture-in-pediatric-age-when-the-treatment-is-mandatory
#3
Simone Salvati, Alberto Maria Settembrini, Daniele Bissacco, Raffaello Dallatana, Daniela Mazzaccaro, Cornelio Crippa, Pietro Romano, Piergiorgio Settembrini
BACKGROUND: Pink pulseless hand syndrome is a rare condition of vascular injury due to distal humerus fracture. It is characterized by radial and ulnar pulselessness in a complex of good hand perfusion which can remain pink and warm. The management and treatment of this condition is still very debated. METHODS: We report four cases of arm traumas which occurred in pediatric patients. In all cases, after the fixation of the fracture by the orthopedic surgeon, the clinical evaluation and duplex ultrasound demonstrated the so called "pink pulseless hand syndrome"...
May 4, 2017: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/28457689/development-of-a-neuro-early-mobilization-protocol-for-use-in-a-neuroscience-intensive-care-unit
#4
Megan A Brissie, Meg Zomorodi, Sharmila Soares-Sardinha, J Dedrick Jordan
OBJECTIVE: Through evaluation of the literature and working with a team of multidisciplinary healthcare providers, our objective was to refine an interprofessional Neuro Early Mobilization Protocol for complex patients in the Neuroscience Intensive Care Unit. RESEARCH METHODOLOGY: Using the literature as a guide, key stakeholders, from multiple professions, designed and refined a Neuro Early Mobilization Protocol. SETTING: This project took place at a large academic medical center in the southeast United States classified as both a Level I Trauma Center and Comprehensive Stroke Center...
April 27, 2017: Intensive & Critical Care Nursing: the Official Journal of the British Association of Critical Care Nurses
https://www.readbyqxmd.com/read/28396009/molecular-mechanisms-of-brain-derived-neurotrophic-factor-in-neuro-protection-recent-developments
#5
REVIEW
Hailin Zhao, Azeem Alam, Chun-Yin San, Shiori Eguchi, Qian Chen, Qingquan Lian, Daqing Ma
Neuronal cell injury, as a consequence of acute or chronic neurological trauma, is a significant cause of mortality around the world. On a molecular level, the condition is characterized by widespread cell death and poor regeneration, which can result in severe morbidity in survivors. Potential therapeutics are of major interest, with a promising candidate being brain-derived neurotrophic factor (BDNF), a ubiquitous agent in the brain which has been associated with neural development and may facilitate protective and regenerative effects following injury...
April 7, 2017: Brain Research
https://www.readbyqxmd.com/read/28394020/-we-will-never-be-normal-the-experience-of-discovering-a-partner-has-autism-spectrum-disorder
#6
Laura F Lewis
Online forums and lay literature suggest that partners of individuals with Autism Spectrum Disorder (ASD) experience depression, distress, and trauma in their everyday lives, exacerbated during the time surrounding diagnosis. In this content analysis, 29 participants were provided with an online open-ended statement asking them to describe in writing their experiences of discovering that their partners had ASD during their relationships. Six themes emerged, including: facing unique challenges within relationships; insisting partners seek diagnosis; initial shock and relief; losing hope for normalcy; making accommodations within relationships; and wishing for professional support...
April 10, 2017: Journal of Marital and Family Therapy
https://www.readbyqxmd.com/read/28284228/interactive-wearable-systems-for-upper-body-rehabilitation-a-systematic-review
#7
REVIEW
Qi Wang, Panos Markopoulos, Bin Yu, Wei Chen, Annick Timmermans
BACKGROUND: The development of interactive rehabilitation technologies which rely on wearable-sensing for upper body rehabilitation is attracting increasing research interest. This paper reviews related research with the aim: 1) To inventory and classify interactive wearable systems for movement and posture monitoring during upper body rehabilitation, regarding the sensing technology, system measurements and feedback conditions; 2) To gauge the wearability of the wearable systems; 3) To inventory the availability of clinical evidence supporting the effectiveness of related technologies...
March 11, 2017: Journal of Neuroengineering and Rehabilitation
https://www.readbyqxmd.com/read/28281921/lateralization-of-neurobiological-response-in-adolescents-with-post-traumatic-stress-disorder-related-to-severe-childhood-sexual-abuse-the-tri-modal-reaction-t-mr-model-of-protection
#8
Tuba Mutluer, Vedat Şar, Çiğdem Kose-Demiray, Harun Arslan, Sibel Tamer, Serap Inal, Anıl Ş Kaçar
This study inquires into neurobiological response to stress and its clinical correlates among adolescents with post-traumatic stress disorder (PTSD). Structural magnetic resonance imaging (MRI) measures of cerebral anatomy were carried out on 23 female adolescents with PTSD related to severe childhood sexual abuse and 21 matched healthy controls. Clinician Administered PTSD Scale for Children and Adolescents, Adolescent Dissociative Experiences Scale, Childhood Trauma Questionnaire, Schedule for Affective Disorders and Schizophrenia for School Age Children, Beck Depression Scale and a set of neuro-cognitive tests were administered to all participants...
March 10, 2017: Journal of Trauma & Dissociation
https://www.readbyqxmd.com/read/28225527/neuro-trauma-or-med-surg-intensive-care-unit-does-it-matter-where-multiple-injuries-patients-with-traumatic-brain-injury-are-admitted-secondary-analysis-of-the-american-association-for-the-surgery-of-trauma-multi-institutional-trials-committee-decompressive
#9
Sarah Lombardo, Thomas Scalea, Jason Sperry, Raul Coimbra, Gary Vercruysse, Toby Enniss, Gregory J Jurkovich, Raminder Nirula
INTRODUCTION: Patients with nontraumatic acute intracranial pathology benefit from neurointensivist care. Similarly, trauma patients with and without traumatic brain injury (TBI) fare better when treated by a dedicated trauma team. No study has yet evaluated the role of specialized neurocritical (NICU) and trauma intensive care units (TICU) in the management of TBI patients, and it remains unclear which TBI patients are best served in NICU, TICU, or general (Med/Surg) ICU. METHODS: This study is a secondary analysis of The American Association for the Surgery of Trauma Multi-Institutional Trials Committee (AAST-MITC) decompressive craniectomy study...
March 2017: Journal of Trauma and Acute Care Surgery
https://www.readbyqxmd.com/read/28217399/delayed-and-isolated-oculomotor-nerve-palsy-following-minor-head-trauma
#10
Yu Nakagawa, Masahiro Toda, Shunsuke Shibao, Kazunari Yoshida
BACKGROUND: The purpose of this study was to consider the mechanism of isolated oculomotor nerve palsy after minor head trauma. CASE DESCRIPTION: We report a rare case of delayed and isolated oculomotor nerve palsy following minor head trauma. A 19-year-old boy complained of double vision 1 day after a minor head trauma. Neuro-ophthalmic examination showed isolated left oculomotor nerve palsy. Computed tomography and magnetic resonance imaging examination revealed no abnormal findings and steroid therapy was administered for a week...
2017: Surgical Neurology International
https://www.readbyqxmd.com/read/28212927/patients-with-chronic-dizziness-following-traumatic-head-injury-typically-have-multiple-diagnoses-involving-combined-peripheral-and-central-vestibular-dysfunction
#11
Q Arshad, R E Roberts, H Ahmad, R Lobo, M Patel, T Ham, D J Sharp, B M Seemungal
OBJECTIVE: We hypothesised that chronic vestibular symptoms (CVS) of imbalance and dizziness post-traumatic head injury (THI) may relate to: (i) the occurrence of multiple simultaneous vestibular diagnoses including both peripheral and central vestibular dysfunction in individual patients increasing the chance of missed diagnoses and suboptimal treatment; (ii) an impaired response to vestibular rehabilitation since the central mechanisms that mediate rehabilitation related brain plasticity may themselves be disrupted...
April 2017: Clinical Neurology and Neurosurgery
https://www.readbyqxmd.com/read/28192386/spectrum-of-magnetic-resonance-imaging-features-in-unilateral-optic-tract-dysfunction
#12
Kristopher M Kowal, Francisco F Rivas Rodriguez, Ashok Srinivasan, Jonathan D Trobe
BACKGROUND: Optic tract dysfunction may be the predominant or only clinical manifestation of an intracranial disorder including mass legion, ischemic infarct, inflammatory disease, and trauma. Documentation of the neuroimaging features of these lesions is limited to reports mostly published before the availability of MRI. This study was undertaken to document the spectrum of MRI features in patients presenting with optic tract dysfunction. METHODS: A retrospective study from 2004 to 2015 at a single tertiary care neuro-ophthalmology service of 24 patients who had unilateral optic tract dysfunction defined by a homonymous hemianopia and a relative afferent pupil defect that could not be attributed to optic neuropathy or retinopathy...
March 2017: Journal of Neuro-ophthalmology: the Official Journal of the North American Neuro-Ophthalmology Society
https://www.readbyqxmd.com/read/28180120/effects-of-a-sensory-stimulation-by-nurses-and-families-on-level-of-cognitive-function-and-basic-cognitive-sensory-recovery-of-comatose-patients-with-severe-traumatic-brain-injury-a-randomized-control-trial
#13
Marzieh Moattari, Fatemeh Alizadeh Shirazi, Nasrin Sharifi, Najaf Zareh
BACKGROUND: Several lines of evidence suggest that early sensory stimulation and regular family visiting programs are potential nursing interventions to improve the outcomes of head injured comatose patients. However, little is known about the impacts of family involvement in providing sensory stimulation. OBJECTIVES: To determine the effects of a sensory stimulation program conducted by nurses and families on the consciousness, level of cognitive function, and basic cognitive sensory recovery of head injury comatose patients...
September 2016: Trauma Monthly
https://www.readbyqxmd.com/read/28158149/a-systematic-review-on-the-prevalence-etiology-and-pathophysiology-of-intrinsic-pain-in-dermal-scar-tissue
#14
Eveline Bijlard, Lisa Uiterwaal, Casimir A E Kouwenberg, Marc A M Mureau, Steven E R Hovius, Frank J P M Huygen
BACKGROUND: Scars can cause pain, even without symptoms of underlying nerve damage. A lack of knowledge on intrinsic scar pain hampers effective treatment of these complaints. OBJECTIVE: Aggregate current knowledge on the prevalence, etiology, and pathophysiology of intrinsic pain in dermal scars. STUDY DESIGN: Systematic review. SETTING: University Medical Center. METHODS: We searched the Embase, Medline, Cochrane central, CINAHL, Web-of-Science, and Pubmed databases with search terms: scar, skin, pain, and etiology/pathology, adding all synonyms of these terms...
February 2017: Pain Physician
https://www.readbyqxmd.com/read/28095731/n-palmitoylethanolamine-oxazoline-pea-oxa-as-a-new-therapeutic-strategy-to-control-neuroinflammation-neuroprotective-effects-in-experimental-models-of-spinal-cord-and-brain-injury
#15
Daniela Impellizzeri, Marika Cordaro, Giuseppe Bruschetta, Rosalba Siracusa, Rosalia Crupi, Emanuela Esposito, Salvatore Cuzzocrea
Modulation of N-acylethanolamine-hydrolyzing acid amidase (NAAA) represents a potential alternative strategy in the treatment of neuroinflammation. Recent studies showed that pharmacological modulation of NAAA could be achieved with the oxazoline of palmitoylethanolamide (PEA) (PEA-OXA). The aim of this study was to evaluate the neuroprotective effects of PEA-OXA in the secondary neuro-inflammatory events induced by spinal and brain trauma in mice. Animals were subjected to spinal cord and brain injury models and PEA-OXA (10 mg/kg) administered both intraperitoneally and orally 1 h and 6 h after trauma...
January 17, 2017: Journal of Neurotrauma
https://www.readbyqxmd.com/read/28067735/migraine-with-aura-or-sports-related-concussion-case-report-pathophysiology-and-multidisciplinary-approach-to-management
#16
Michael J Ellis, Dean Cordingley, Richard Girardin, Lesley Ritchie, Janine Johnston
The evaluation and management of athletes presenting with clinical features of migraine headache with aura in the setting of sports-related head trauma is challenging. We present a case report of a 15-yr-old boy with a history of migraine with visual aura that developed acute visual disturbance and headache after a head injury during an ice hockey game. The patient underwent comprehensive assessment at a multidisciplinary concussion program, including neuro-ophthalmological examination, neurocognitive testing, and graded aerobic treadmill testing...
January 2017: Current Sports Medicine Reports
https://www.readbyqxmd.com/read/28030487/neuro-trauma-or-med-surg-icu-does-it-matter-where-polytrauma-patients-with-tbi-are-admitted-secondary-analysis-of-aast-mitc-decompressive-craniectomy-study
#17
Sarah Lombardo, Thomas Scalea, Jason Sperry, Raul Coimbra, Gary Vercruysse, Gregory J Jurkovich, Ram Nirula
INTRODUCTION: Patients with non-traumatic acute intracranial pathology benefit from neurointensivist care. Similarly, trauma patients with and without TBI fare better when treated by a dedicated trauma team. No study has yet evaluated the role of specialized neurocritical (NICU) and trauma intensive care units (TICU) in the management of TBI patients, and it remains unclear which TBI patients are best served in NICU, TICU, or general (Med/Surg) ICU. METHODS: This study is a secondary analysis of The American Association for the Surgery of Trauma Multi-Institutional Trials Committee (AAST-MITC) decompressive craniectomy study...
December 23, 2016: Journal of Trauma and Acute Care Surgery
https://www.readbyqxmd.com/read/27995066/functional-resting-state-fmri-connectivity-correlates-with-serum-levels-of-the-s100b-protein-in-the-acute-phase-of-traumatic-brain-injury
#18
William Hedley Thompson, Eric Peter Thelin, Anders Lilja, Bo-Michael Bellander, Peter Fransson
The S100B protein is an intra-cellular calcium-binding protein that mainly resides in astrocytes in the central nervous system. The serum level of S100B is used as biomarker for the severity of brain damage in traumatic brain injury (TBI) patients. In this study we investigated the relationship between intrinsic resting-state brain connectivity, measured 1-22 days (mean 8 days) after trauma, and serum levels of S100B in a patient cohort with mild-to-severe TBI in need of neuro-intensive care in the acute phase...
2016: NeuroImage: Clinical
https://www.readbyqxmd.com/read/27886890/orbital-disease-in-neuro-ophthalmology
#19
REVIEW
Jessica R Chang, Anna M Gruener, Timothy J McCulley
Many abnormalities of the orbit present with neuro-ophthalmic findings, such as impaired ocular motility or alignment, and sensory changes, including optic neuropathy. Comprehensive coverage of all orbital diseases is beyond the scope of this article. This review focuses on diagnosis and management of the most common and the most vision- or life-threatening orbital conditions as well as more recently discovered entities and points of active controversy. These conditions include orbital trauma, vascular disease, inflammatory and infectious diseases, and neoplasms...
February 2017: Neurologic Clinics
https://www.readbyqxmd.com/read/27812348/an-attempt-of-early-detection-of-poor-outcome-after-whiplash
#20
Sebastien Laporte, Danping Wang, Jennyfer Lecompte, Sophie Blancho, Baptiste Sandoz, Antoine Feydy, Pavel Lindberg, Julien Adrian, Elodie Chiarovano, Catherine de Waele, Pierre-Paul Vidal
The main concern with whiplash is that a large proportion of whiplash patients experience disabling symptoms or whiplash-associated disorders (WAD) for months if not years following the accident. Therefore, identifying early prognostic factors of WAD development is important as WAD have widespread clinical and economic consequences. In order to tackle that question, our study was specifically aimed at combining several methods of investigation in the same WAD patients at the acute stage and 6 months later...
2016: Frontiers in Neurology
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