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https://www.readbyqxmd.com/read/29126716/antitumor-and-antimetastatic-effects-of-walnut-oil-in-esophageal-adenocarcinoma-cells
#1
Saime Batirel, Ayse Mine Yilmaz, Ali Sahin, Nikolaos Perakakis, Nesrin Kartal Ozer, Christos S Mantzoros
BACKGROUND: Walnuts contain many components including specific fatty acids, which could be active against cancer. Even though the anticarcinogenic effect of some of the individual fatty acids in walnut oil has been described, the effect of walnut oil itself on esophageal cancer cells hasn't yet been investigated. OBJECTIVE: We aimed to investigate whether walnut oil affects tumor growth and metastatic potential in esophageal cancer cells. METHODS: The human esophageal adenocarcinoma cell line, OE19, was treated with different doses of walnut oil and cell viability, apoptosis/necrosis and cell cycle analyses were performed using WST-1 assay and flow cytometry respectively...
November 1, 2017: Clinical Nutrition: Official Journal of the European Society of Parenteral and Enteral Nutrition
https://www.readbyqxmd.com/read/29115040/telecytology-is-it-possible-with-smartphone-images
#2
Davut Sahin, Uguray Payam Hacisalihoglu, Saime Hale Kirimlioglu
INTRODUCTION: This study aimed to discuss smartphone usage in telecytology and determine intraobserver concordance between microscopic cytopathological diagnoses and diagnoses derived via static smartphone images. METHODS: The study was conducted with 172 cytologic material. A pathologist captured static images of the cytology slides from the ocular lens of a microscope using a smartphone. The images were transferred via WhatsApp® to a cytopathologist working in another center who made all the microscopic cytopathological diagnoses 5-27 months ago...
November 8, 2017: Diagnostic Cytopathology
https://www.readbyqxmd.com/read/29094281/author-correction-to-in-vitro-drug-release-after-crushing-evaluation-of-xtampza-%C3%A2-er-and-other-er-opioid-formulations
#3
Stephen P Mayock, Said Saim, Alison B Fleming
Following correction should be noted.
November 1, 2017: Clinical Drug Investigation
https://www.readbyqxmd.com/read/29069322/rapid-determination-of-non-steroidal-anti-inflammatory-drugs-in-aquatic-matrices-by-two-phase-micro-electrodriven-membrane-extraction-combined-with-liquid-chromatography
#4
Nor Suhaila Mohamad Hanapi, Mohd Marsin Sanagi, Abd Khamim Ismail, Nor'ashikin Saim, Wan Nazihah Wan Ibrahim, Wan Aini Wan Ibrahim, Faridah Mohd Marsin
Two-phase micro-electrodriven membrane extraction (EME) procedure for the pre-concentration of selected non-steroidal anti-inflammatory drugs (NSAIDs) in aquatic matrices was investigated. Agarose film was used as interface between donor and acceptor phase in EME which allowed for selective extraction of the analytes prior to high performance liquid chromatography-ultraviolet detection. Charged analytes were transported from basic aqueous sample solution through agarose film into 1-octanol as an acceptor phase at 9 V potential...
October 23, 2017: Journal of Chromatographic Science
https://www.readbyqxmd.com/read/29046499/the-assessment-of-total-antioxidant-capacity-and-superoxide-dismutase-levels-and-the-possible-role-of-manganese-superoxide-dismutase-polymorphism-in-acromegaly
#5
Muzaffer Ilhan, Seda Turgut, Saime Turan, Sema Demirci Cekic, Hayriye Arzu Ergen, Gurbet Korkmaz Dursun, Brunilda Mezani, Ozcan Karaman, Ilhan Yaylim, Mustafa Resat Apak, Ertugrul Tasan
Oxidative status is attributed to endothelial dysfunction and might be one of the key mechanisms of endothelial dysfunction in acromegaly. In this study, we aimed to investigate the effect of acromegaly on superoxide dismutase (SOD) and total antioxidant capacity (TAC) levels, and the possible influence of human manganese superoxide dismutase (MnSOD) polymorphism on these levels. 51 acromegaly patients and 57 age and sex matched healthy subjects were recruited to the study in Bezmialem Vakif University Hospital between 2011 and 2014...
October 17, 2017: Endocrine Journal
https://www.readbyqxmd.com/read/29034408/occurrence-of-organochlorine-pesticides-in-a-tropical-lake-basin
#6
Zati Sharip, Norbaya Hashim, Saim Suratman
This study investigates the presence and distribution of organochlorine pesticides in streams and the lake in the Sembrong Lake Basin in Malaysia. The catchment of Sembrong Lake has been converted to agricultural areas over the past 30 years, with oil palm plantations and modern agricultural farming being the main land use. Surface water samples were collected from eight sites comprising the stream and lake and analysed for 19 organochlorine pesticides (OCPs). In situ measurement of temperature, dissolved oxygen, pH and conductivity were also undertaken at each site...
October 15, 2017: Environmental Monitoring and Assessment
https://www.readbyqxmd.com/read/28987719/supplementation-of-docosahexaenoic-acid-dha-eicosapentaenoic-acid-epa-in-a-ratio-of-1-1-3-during-the-last-trimester-of-pregnancy-results-in-epa-accumulation-in-cord-blood
#7
Nihal Büyükuslu, Sema Ovalı, Şükriye Leyla Altuntaş, Saime Batırel, Pakize Yiğit, Muazzez Garipağaoğlu
Omega-3 fatty acids (n-3 FA), specifically DHA, are associated with fetal growth and development. We aimed to determine the levels of DHA and EPA in cord serum after n-3 FA supplementation during the last trimester of pregnancy. Among 55 women, 23 were administered daily one capsule of n-3 FA supplement, involving DHA/EPA in a ratio of 1/1.3. Twenty nine women were enrolled as control group. Blood samples were collected at 22-24 weeks of gestation and at delivery. Fatty acids were analyzed with the method of GC-MS...
October 2017: Prostaglandins, Leukotrienes, and Essential Fatty Acids
https://www.readbyqxmd.com/read/28965968/adsorption-of-malachite-green-from-aqueous-solution-by-using-novel-chitosan-ionic-liquid-beads
#8
Faizah Naseeruteen, Nur Shahirah Abdul Hamid, Faiz Bukhari Mohd Suah, Wan Saime Wan Ngah, Faizatul Shimal Mehamod
Chitosan ionic liquid beads were prepared from chitosan and 1-butyl-3-methylimidazolium based ionic liquids to remove Malachite Green (MG) from aqueous solutions. Batch adsorption experiments were carried out as a function of initial pH, adsorbent dosage, agitation time and initial MG concentration. The optimum conditions were obtained at pH 4.0, 0.008g of adsorbent dosage and 20min of agitation time were utilized in the kinetic and isotherm studies. Three kinetic models were applied to analyze the kinetic data and pseudo-second order was found to be the best fitted model with R(2)>0...
September 28, 2017: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/28940174/in-vitro-drug-release-after-crushing-evaluation-of-xtampza-%C3%A2-er-and-other-er-opioid-formulations
#9
Stephen P Mayock, Said Saim, Alison B Fleming
BACKGROUND AND OBJECTIVE: Extended-release (ER) opioids are associated with high rates of abuse. Recreational opioid users often manipulate ER formulations to achieve a high plasma concentration in a short amount of time, resulting in a more rapid and intense high. Patients may also manipulate ER tablets to facilitate swallowing, without recognizing that manipulation could increase release rate. The goal of this study was to assess the ability of oxycodone DETERx (Xtampza(®) ER, Collegium Pharmaceutical, Inc...
September 22, 2017: Clinical Drug Investigation
https://www.readbyqxmd.com/read/28929760/a-classic-azo-dye-agglomeration-system-evidence-for-slow-continuous-nucleation-autocatalytic-agglomerative-growth-plus-the-effects-of-dust-removal-by-microfiltration-on-the-kinetics
#10
Saim Özkar, Richard G Finke
An important but virtually ignored 1978 paper by Reeves and co-workers, which examined a dye-OAc hydrolysis and then agglomeration system, is reanalyzed in light of current state of knowledge of nucleation and growth/agglomeration phenomena. The Finke-Watzky two-step mechanism is used to account quantitatively for the kinetics data, in turn providing deconvolution of dye hydrolysis and nucleation of agglomerative growth, from the agglomerative growth step, including their separate rate constants. Significantly, the effects of microfiltration of the removable dust on the two steps and their rate constants are uncovered and quantitated for the first time, including the finding that the presence of dust accelerates both steps by ca...
September 20, 2017: Journal of Physical Chemistry. A
https://www.readbyqxmd.com/read/28894402/attachment-proliferation-and-morphological-properties-of-human-dermal-fibroblasts-on-ovine-tendon-collagen-scaffolds-a-comparative-study
#11
Fauzi Mh Busra, Yogeswaran Lokanathan, Masrina Mohd Nadzir, Aminuddin Saim, Ruszymah Bt Hj Idrus, Shiplu Roy Chowdhury
INTRODUCTION: Collagen type I is widely used as a biomaterial for tissue-engineered substitutes. This study aimed to fabricate different three-dimensional (3D) scaffolds using ovine tendon collagen type I (OTC-I), and compare the attachment, proliferation and morphological features of human dermal fibroblasts (HDF) on the scaffolds. METHODS: This study was conducted between the years 2014 to 2016 at the Tissue Engineering Centre, UKM Medical Centre. OTC-I was extracted from ovine tendon, and fabricated into 3D scaffolds in the form of sponge, hydrogel and film...
March 2017: Malaysian Journal of Medical Sciences: MJMS
https://www.readbyqxmd.com/read/28861309/isolation-and-in-vitro-cultivation-of-human-urine-derived-cells-an-alternative-stem-cell-source
#12
Seçil Erden Tayhan, Gönül Tezcan Keleş, İsmet Topçu, Erol Mir, Saime İsmet Deliloğlu Gürhan
OBJECTIVE: For in vitro tissue engineering in urology, stem cells are commonly isolated from tissue specimens obtained during open or endoscopic surgery. Within the context of the present study our aim was to isolate cells from human urine by an alternative and safe technique rather than using the indicated method. MATERIAL AND METHODS: After human urine samples had been collected from young and healthy donors via urethral catheterization, cells were precipitated by centrifugation and cultured...
September 2017: Turkish Journal of Urology
https://www.readbyqxmd.com/read/28857214/sexual-assault-in-the-us-military-a-comparison-of-risk-in-deployed-and-non-deployed-locations-among-operation-enduring-freedom-operation-iraqi-freedom-active-component-and-reserve-national-guard-servicewomen
#13
Anne G Sadler, Brenda M Booth, James C Torner, Michelle A Mengeling
BACKGROUND: To determine whether sexual assault in the military (SAIM) among active component and Reserve/National Guard servicewomen is more likely to occur in deployed or non-deployed locations; and which location poses greater risk for SAIM when time spent in-location is considered. METHODS: A total of 1337 Operation Enduring Freedom/Operation Iraqi Freedom era servicewomen completed telephone interviews eliciting socio-demographics, military and sexual assault histories, including attempted and completed sexual assault...
November 2017: American Journal of Industrial Medicine
https://www.readbyqxmd.com/read/28844187/evaluation-of-oxidative-status-in-patients-with-chronic-periodontitis-and-polycystic-ovary-syndrome-a-cross-sectional-study
#14
Ebru Saglam, Cenk Fatih Canakcı, Saime Ozbek Sebin, Nesrin Saruhan, Metin Ingec, Hümeyra Canakcı, Ufuk Sezer
BACKGROUND: The aim of the present study was to investigate the salivary and serum 8-hydroxy-2´-deoxyguanosine (8-OHdG) and malondialdehyde (MDA) levels as well as total antioxidant status (TAS), in females with chronic periodontitis (CP) and polycystic ovary syndrome (PCOS), compared to healthy females. METHODS: Four groups, each consisting of 22 individuals, respectively women with both PCOS and CP (PCOSCP), systemically healthy women with CP (CP), periodontally healthy women with PCOS (PCOSPH) and periodontally and systemically healthy women (PH)...
August 28, 2017: Journal of Periodontology
https://www.readbyqxmd.com/read/28843925/nickel-0-nanoparticles-supported-on-bare-or-coated-cobalt-ferrite-as-highly-active-magnetically-isolable-and-reusable-catalyst-for-hydrolytic-dehydrogenation-of-ammonia-borane
#15
Joydev Manna, Serdar Akbayrak, Saim Özkar
Nickel(0) nanoparticles supported on cobalt ferrite (Ni(0)/CoFe2O4), polydopamine coated cobalt ferrite (Ni(0)/PDA-CoFe2O4) or silica coated cobalt ferrite (Ni(0)/SiO2-CoFe2O4) are prepared and used as catalysts in hydrogen generation from the hydrolysis of ammonia borane at room temperature. Ni(0)/CoFe2O4 (4.0% wt. Ni) shows the highest catalytic activity with a TOF value of 38.3min(-1) in hydrogen generation from the hydrolysis of ammonia borane at 25.0±0.1°C. However, the initial catalytic activity of Ni(0)/CoFe2O4 catalyst is not preserved in subsequent runs of hydrolysis...
August 16, 2017: Journal of Colloid and Interface Science
https://www.readbyqxmd.com/read/28811845/role-of-contrast-enhancement-and-corrected-attenuation-values-of-renal-tumors-in-predicting-renal-cell-carcinoma-rcc-subtypes-protocol-for-a-triphasic-multi-slice-computed-tomography-ct-procedure
#16
Ersen Ertekin, Akın Soner Amasyalı, Bulent Erol, Saim Acikgozoglu, Faruk Kucukdurmaz, Alaaddin Nayman, Haluk Erol
BACKGROUND: To distinguish RCC subtypes based on contrast enhancement features of CT images. MATERIAL/METHODS: In total, 59 lesions from 57 patients were included. All patients underwent multi-slice CT imaging with a triphasic protocol, which included non-contrast, corticomedullary, nephrographic and urographic phases. Contrast enhancement features of renal masses were evaluated in terms of CT attenuation values (AV) and differences in contrast density; the aorta or renal parenchyma were evaluated based on corrected or relative values...
2017: Polish Journal of Radiology
https://www.readbyqxmd.com/read/28748902/acute-renal-failure-secondary-to-drug-related-crystalluria-and-or-drug-reaction-with-eosinophilia-and-systemic-symptom-syndrome-in-a-patient-with-metastatic-lung-cancer
#17
Saime Paydas, Mustafa Balal, Firat Kocabas, Nurettin Ay
Drug reaction with eosinophilia and systemic symptoms (DRESS) or drug-induced hypersensitivity is a severe adverse drug-induced reaction. Aromatic anticonvulsants, such as phenytoin, phenobarbital, and carbamazepine, and some drugs, can induce DRESS. Atypical crystalluria can be seen in patients treated with amoxycillin or some drugs and can cause acute renal failure. We describe a 66-year-old man who presented fever and rash and acute renal failure three days after starting amoxycillin. He was also using phenytoin because of cerebral metastatic lung cancer...
July 2017: Saudi Journal of Kidney Diseases and Transplantation
https://www.readbyqxmd.com/read/28748415/role-of-plasma-derived-fibrin-on-keratinocyte-and-fibroblast-wound-healing
#18
Jia Xian Law, Shiplu Roy Chowdhury, Bin Saim Aminuddin, Binti Haji Idrus Ruszymah
Fibrin has excellent biocompatibility and biological properties to support tissue regeneration and promote wound healing. However, the role of diluted fibrin in wound healing has yet to be elucidated as it is commonly used in high concentration. This study was aimed to examine the effects of diluted plasma-derived fibrin (PDF) on keratinocyte and fibroblast wound healing in term of cell proliferation, migration, extracellular matrix (ECM) production and soluble factor secretion. Two PDF concentrations, 10 and 20% (v/v) were tested on keratinocytes and fibroblasts indirectly co-cultured in the transwell system...
July 26, 2017: Cell and Tissue Banking
https://www.readbyqxmd.com/read/28746195/the-immediate-effect-of-facial-candling-on-inflammatory-mediators-substance-p-symptoms-severity-and-quality-of-life-in-allergic-rhinitis-patients-study-protocol-for-a-randomized-controlled-trial
#19
RANDOMIZED CONTROLLED TRIAL
Nor Faizatul Fatikah Ismail, Chin Fen Neoh, Siong Meng Lim, Amir Heberd Abdullah, Mohd Fahmi Mastuki, Kalavathy Ramasamy, Nazli Zainuddin, Lokman Saim, Long Chiau Ming
INTRODUCTION: Asian countries have a variety of ethnic groups and culture that provide their own traditional treatment in health care. Facial candling appears to be one of the popular traditional treatments in Southeast Asian. The complementary medicine practitioners promote that the facial candling treatment would help in reducing the symptoms of allergic rhinitis and other problems related to sinus. Due to the lack of evidence available, the effectiveness of this treatment method and its mechanism, however, remains unknown...
July 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28743076/lc-ms-ms-esi-method-for-simultaneous-quantification-of-darolutamide-and-its-active-metabolite-orm-15341-in-mice-plasma-and-its-application-to-a-pharmacokinetic-study
#20
Sreekanth Dittakavi, Pavan Kumar V S P Nagasuri, Suresh P Sulochana, Syed Mohd Saim, Sadanand R Mallurwar, Mohd Zainuddin, Purushottam Dewang, Sriram Rajagopal, Ramesh Mullangi
A sensitive and rapid LC-MS/MS method was developed and validated for the simultaneous quantitation of darolutamide and its active metabolite i.e. ORM-15341 in 50μL mice plasma using bicalutamide as an internal standard (I.S.) as per regulatory guidelines. Sample processing was accomplished through liquid-liquid extraction. Chromatographic separation was achieved using an Atlantis C18 column with an isocratic mobile phase comprising 0.2% formic acid:acetonitrile (35:65, v/v) at a flow rate of 0.8mL/min within 2...
October 25, 2017: Journal of Pharmaceutical and Biomedical Analysis
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