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İnci Arıkan, Aynur Gülcan, Saime Ergen Dıbeklıoğlu
AIM: The aim of the study was to determine the incidence of intestinal parasitic diseases (IPD) and associated factors in primary school students and to assess the knowledge and practices of mothers about these diseases. METHODS: This is a cross-sectional study carried out in January-March 2014 in 471 students aged 5-11 years, studying at 3 schools randomly selected from the city centre regions with different socioeconomic levels. Stratified sampling method was used in the present study and the data were collected in two stages...
September 2016: Central European Journal of Public Health
Saime Burce Ozler, Ezgi Bakirci, Can Kucukgul, Bahattin Koc
Bioprinting is a relatively new technology where living cells with or without biomaterials are printed layer-by-layer in order to create three-dimensional (3D) living structures. In this article, novel bioprinting methodologies are developed to fabricate 3D biological structures directly from computer models using live multicellular aggregates. Multicellular aggregates made out of at least two cell types from fibroblast, endothelial and smooth muscle cells are prepared and optimized. A novel bioprinting approach is proposed in order to continuously extrude cylindrical multicellular aggregates through the bioprinter's glass microcapillaries...
September 30, 2016: Journal of Biomedical Materials Research. Part B, Applied Biomaterials
Hina Rehman, Muhammad Saim Khan, Muhammad Nafees, Attique Ur Rehman, Asad Habib
OBJECTIVE: To compare the mean optic nerve sheath diameter (ONSD) in patients with idiopathic intracranial hypertension (IIH) versus normal healthy individuals using B-scan ultrasonography as diagnostic tool. STUDY DESIGN: Cross-sectional analytical study. PLACE AND DURATION OF STUDY: Armed Forces Institute of Radiology and Imaging, Rawalpindi, Pakistan, from June to December 2015. METHODOLOGY: Participants aged 30 - 50 years were divided into two groups...
September 2016: Journal of the College of Physicians and Surgeons—Pakistan: JCPSP
Oktay Karaköse, Hüseyin Eken, Ali Naki Ulusoy, Hüseyin Koray Topgül, Mehmet Bilgin, Saim Savaş Yürüker, Mustafa Yavuz Gülbahar
Intestinal anastomosis healing is a complex physiological process in which many local and systemic factors play a role. One of the significant cytokines in this process is TNF-α. Infliximab is a chimeric monoclonal antibody which binds to TNF-α with high affinity. Although this agent is used in ulcerative colitis and Crohn's disease, intestinal surgery may be required in these patients. In this study it was aimed to determine whether or not there was any negative effect of preoperative single dose infliximab treatment on intestinal anastomosis healing...
2016: Prague Medical Report
Osman Güvenç, Saime Sündüs Uygun, Derya Çimen, Eyüp Aslan, Ali Annagür
Jeune syndrome (Asphyxiating thoracic dysplasia) is a rare dystrophy of the skeleton, inherited as an autosomal recessive condition. Patients develop a narrowed thorax, rhizomelic dwarfism, and hepatic, renal, and pancreatic abnormalities. High rates of pulmonary hypoplasia and pulmonary hypertension have been reported. Some patients die in early stages of life due to respiratory failure. The case of a patient referred with a history of severe asphyxiating birth, who had been diagnosed with Jeune syndrome and later hypertrophic cardiomyopathy (HCM) upon echocardiographic examination is described in the present report...
September 2016: Türk Kardiyoloji Derneği Arşivi: Türk Kardiyoloji Derneğinin Yayın Organıdır
Muhammad Saim Khan, Imran Basit, Mazhar Ishaq, Tariq Shakoor, Amer Yaqub, Rana Intisar
OBJECTIVE: To determine mean change in visual acuity, central corneal thickness and symptoms in patients with pseudophakic bullous keratopathy after treatment with corneal collagen crosslinking. METHODS: This quasi experimental study was conducted at Armed Forces Institute of Ophthalmology, Rawalpindi, Pakistan from April 2015 to Nov 2015. A total of 24 eyes of 24 patients were included in the study. Visual symptoms were graded in five grades (Grade 1-5), Grade-1 being very mild with decreased vision only while patients with all five symptoms (decreased vision, foreign body sensations, pain, watering and photophobia) were graded as Grade-5...
July 2016: Pakistan Journal of Medical Sciences Quarterly
Mohammad Aref Khalily, Hamit Eren, Serdar Akbayrak, Hepi Hari Susapto, Necmi Biyikli, Saim Özkar, Mustafa O Guler
Three-dimensional (3D) porous metal and metal oxide nanostructures have received considerable interest because organization of inorganic materials into 3D nanomaterials holds extraordinary properties such as low density, high porosity, and high surface area. Supramolecular self-assembled peptide nanostructures were exploited as an organic template for catalytic 3D Pt-TiO2 nano-network fabrication. A 3D peptide nanofiber aerogel was conformally coated with TiO2 by atomic layer deposition (ALD) with angstrom-level thickness precision...
September 26, 2016: Angewandte Chemie
Songül Meltem Can, Osman Nuri Türkmenoğlu, Canan Tanik, Ender Uysal, Barış Özöner, Saime Ayça Kaldirimoğlu, Ahmet Murat Müslüman, Adem Yilmaz, Halit Çavuşoğlu, Çiçek Bayindir, Yunus Aydin
AIM: CT-guided stereotactic brain biopsy has been performed in our clinic since March 1998. In this prospective study, we examined the patient data undergoing stereotactic biopsy and the results of biopsies in consecutive 500 patients. MATERIAL AND METHODS: Between the dates of March 1998 and January 2015, CT guided stereotactic biopsies were performed by using the Leksell stereotactic frame system (Elekta Instruments EU, Sweden) in 500 patients. A total of 512 procedures were performed in patients consisting of 184 females (36...
January 25, 2016: Turkish Neurosurgery
Yogeswaran Lokanathan, Norazzila Omar, Nur Nabilah Ahmad Puzi, Aminuddin Saim, Ruszymah Hj Idrus
Centella asiatica, locally well known in Malaysia as pegaga, is a traditional herb that has been used widely in Ayurvedic medicine, traditional Chinese medicine, and in the traditional medicine of other Southeast Asian countries including Malaysia. Although consumption of the plant is indicated for various illnesses, its potential neuroprotective properties have been well studied and documented. In addition to past studies, recent studies also discovered and/or reconfirmed that C. asiatica acts as an antioxidant, reducing the effect of oxidative stress in vitro and in vivo...
January 2016: Malaysian Journal of Medical Sciences: MJMS
Winnie de Bruijn, Cristina Ibáñez, Pia Frisk, Hanne Bak Pedersen, Ali Alkan, Patricia Vella Bonanno, Ljiljana S Brkičić, Anna Bucsics, Guillaume Dedet, Jaran Eriksen, Joseph O Fadare, Jurij Fürst, Gisselle Gallego, Isabella P Godói, Augusto A Guerra Júnior, Hakkı Gürsöz, Saira Jan, Jan Jones, Roberta Joppi, Saim Kerman, Ott Laius, Newman Madzikwa, Einar Magnússon, Mojca Maticic, Vanda Markovic-Pekovic, Amos Massele, Olayinka Ogunleye, Aisling O'Leary, Jutta Piessnegger, Catherine Sermet, Steven Simoens, Celda Tiroyakgosi, Ilse Truter, Magnus Thyberg, Kristina Tomekova, Magdalena Wladysiuk, Sotiris Vandoros, Elif H Vural, Corinne Zara, Brian Godman
BACKGROUND: Infection with the Hepatitis C Virus (HCV) is a widespread transmittable disease with a diagnosed prevalence of 2.0%. Fortunately, it is now curable in most patients. Sales of medicines to treat HCV infection grew 2.7% per year between 2004 and 2011, enhanced by the launch of the protease inhibitors (PIs) boceprevir (BCV) and telaprevir (TVR) in addition to ribavirin and pegylated interferon (pegIFN). Costs will continue to rise with new treatments including sofosbuvir, which now include interferon free regimens...
2016: Frontiers in Pharmacology
Mukadder Şanli, Nurçin Gülhaş, Bilge Türk Bilen, Gülay Erdoğan Kayhan, Muharrem Uçar, Ahmet Hamdi Aytekin, Saim Yoloğlu
BACKGROUND/AIM: The objective of this study was to examine the effect of addition of subanesthetic doses of ketamine to an epinephrine-lidocaine solution on postoperative pain, analgesic use, and patient comfort during rhinoplasties. MATERIALS AND METHODS: Ninety patients were randomly divided into three groups: Group L, lidocaine with epinephrine; Group K, lidocaine with epinephrine plus ketamine; and Group S (control group), physiological saline solution with epinephrine...
2016: Turkish Journal of Medical Sciences
Ahsan Mukhtar, Sidra Malik, Muhammad Saim Khan, Mazhar Ishaq
Retinal artery occlusion is an uncommon condition but can lead to grave consequences if not managed in time. Elderly population with other comorbid conditions like hypertension, ischemic heart disease, hyperlipidemia and stroke are commonly affected. However, this condition may affect younger population with entirely different systemic associations. Thromboembolism, which usually takes place secondary to cardiac emboli or hypercoagulable states cause retinal artery occlusion in young population. A24-year lady presented with a short history of unilateral altitudinal visual loss...
July 2016: Journal of the College of Physicians and Surgeons—Pakistan: JCPSP
Carlos Huerta, Xin Jiang, Isaac Trevino, Christopher F Bender, Deborah A Ferguson, Brandon Probst, Kerren K Swinger, Vincent S Stoll, Philip J Thomas, Irina Dulubova, Melean Visnick, W Christian Wigley
BACKGROUND: Semi-synthetic oleanane triterpenoid antioxidant inflammation modulators (tpAIMs) are small molecules that interact with KEAP1 cysteine residue 151 (C151) and activate NRF2. Exploration of the structure-activity relationship between the tpAIMs and KEAP1 is limited by the predominantly hydrocarbon nature of the oleanane triterpenoid pentacyclic ring structure. Therefore, we used novel, chemically-tractable, synthetic antioxidant inflammation modulators (sAIMs) to probe the stereoselectivity of the ligand-protein interaction...
November 2016: Biochimica et Biophysica Acta
Şebnem Koldaş Doğan, Saime Ay, Deniz Evcik
OBJECTIVE: The purpose of this study was to compare the effectiveness of two different laser therapy regimens on pain, lumbar range of motions (ROM) and functional capacity in patients with chronic low back pain (CLBP). METHODS: Forty nine patients with CLBP were randomly assigned into two groups. Group 1 (n= 20) received hot-pack + laser therapy 1 (wavelength of 850 nm Gallium-Aluminum-Arsenide (Ga-Al-As) laser); group 2 (n= 29) received hot-pack + laser therapy 2 (wavelength of 650 nm Helyum-Neon (He-Ne), 785 ve 980 nm Gal-Al-As combined plaque laser) for 15 sessions...
July 21, 2016: Journal of Back and Musculoskeletal Rehabilitation
Huseyin Konur, Gulay Erdogan Kayhan, Huseyin Ilksen Toprak, Nizamettin Bucak, Mustafa Said Aydogan, Saim Yologlu, Mahmut Durmus, Sezai Yılmaz
Fluid management is challenging and still remains controversial in orthotopic liver transplantation (OLT). The pleth variability index (PVI) has been shown to be a reliable predictor of fluid responsiveness of perioperative and critically ill patients; however, it has not been evaluated in OLT. This study was designed to examine whether the PVI can reliably predict fluid responsiveness in OLT and to compare PVI with other hemodynamic indexes that are measured using the PiCCO2 monitoring system. Twenty-five patients were enrolled in this study...
July 2016: Kaohsiung Journal of Medical Sciences
Saim Sağ, Ömer Fatih Nas, Ömer Bedir, İbrahim Baran, Sümeyye Güllülü, Bahattin Hakyemez
No abstract text is available yet for this article.
July 2016: Anatolian Journal of Cardiology
Gulbu Isitmangil, Gunay Gurleyik, Fugen Vardar Aker, Cihan Coskun, Ozlem Kucukhuseyin, Soykan Arikan, Saime Turan, Canan Kelten Talu, Mehmet Baki Dogan, Ammad Ahmad Farooqi, Ilhan Yaylim
BACKGROUND/AIM: Breast cancer is one of the most common and lethal types of cancer among women. We focused on the importance of the immune system in the etiology of breast cancer by investigating critical polymorphisms of cytotoxic T-lymphocyte-associated protein 4 (CTLA4) and cluster of differentiation 28 (CD28) gene, and circulating levels of these proteins. MATERIALS AND METHODS: A total of 79 patients with breast cancer and 76 healthy controls were enrolled...
July 2016: In Vivo
Saim Sağ, Abdülmecit Yıldız, Aysel Aydin Kaderli, Bülent Cuma Gül, Ömer Bedir, Ercan Ceğilli, Bülent Özdemir, Fatma Ezgi Can, Ali Aydınlar
BACKGROUND: Contrast induced nephropathy (CIN) has been proven to be a clinical condition related to adverse cardiovascular outcomes. In recent studies, the monocyte to high density lipoprotein ratio (MHR) has been postulated as a novel parameter associated with adverse renal and cardiovascular outcomes. In this study we investigated the association of MHR with CIN in ST-segment elevation myocardial infarction (STEMI) patients treated with primary percutaneous coronary intervention (PCI)...
June 22, 2016: Clinical Chemistry and Laboratory Medicine: CCLM
Alexandre Loukanov, Saim Emin
We report the microemulsion synthesis of vanadium and chromium sulfide nanoparticles (NPs) and their biological application as nanoprobes for colocalization of membrane proteins. Spherical V2 S3 and Cr2 S3 NPs were prepared in reverse microemulsion droplets, as nanoreactors, obtained by the surfactant sodium bis(2-ethylhexyl) sulfosuccinate (AOT) in nonpolar organic phase (heptane). Electron microscopic data indicated that the size distribution of the nanoparticles was uniform with an average diameter between 3 ÷ 5 nm...
September 2016: Microscopy Research and Technique
Serdar Akbayrak, Yalçın Tonbul, Saim Özkar
Ruthenium(0) nanoparticles supported on ceria (Ru(0)/CeO2) were in situ generated from the reduction of ruthenium(iii) ions impregnated on ceria during the hydrolysis of ammonia borane. Ru(0)/CeO2 was isolated from the reaction solution by centrifugation and characterized by ICP-OES, BET, XRD, TEM, SEM-EDS and XPS techniques. All the results reveal that ruthenium(0) nanoparticles were successfully supported on ceria and the resulting Ru(0)/CeO2 is a highly active, reusable and long-lived catalyst for hydrogen generation from the hydrolysis of ammonia borane with a turnover frequency value of 361 min(-1)...
July 5, 2016: Dalton Transactions: An International Journal of Inorganic Chemistry
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