keyword
MENU ▼
Read by QxMD icon Read
search

SAIM

keyword
https://www.readbyqxmd.com/read/27925271/validation-of-an-lc-ms-ms-method-for-simultaneous-detection-of-four-hdac-inhibitors-belinostat-panobinostat-rocilinostat-and-vorinostat-in-mice-plasma-and-its-application-to-a-mice-pharmacokinetic-study
#1
Kalpesh Kumar Giri, Suresh P S, Syed Mohd Saim, Mohd Zainuddin, Ravi Kanth Bhamidipati, Purushottam Dewang, Mahanandeesha S Hallur, Sridharan Rajagopal, Sriram Rajagopal, Ramesh Mullangi
A sensitive and rapid LC-MS/MS method was developed and validated for the simultaneous quantitation of four HDAC inhibitors namely belinostat (BST), panobinostat (PST), rocilinostat (RST) and vorinostat (VST) in mice plasma as per regulatory guidelines. The analytes and internal standard were extracted from 50 μL mice plasma by protein precipitation, followed by chromatographic separation using an Atlantis C18 column with an isocratic mobile phase comprising 0.1% formic acid: acetonitrile (25:75,, v/v) at a flow rate of 0...
December 7, 2016: Biomedical Chromatography: BMC
https://www.readbyqxmd.com/read/27900891/chondrogenesis-of-human-adipose-derived-stem-cells-for-future-microtia-repair-using-co-culture-technique
#2
Bee See Goh, Siti Nurhadis Che Omar, Muhammad Azhan Ubaidah, Lokman Saim, Shamsul Sulaiman, Kien Hui Chua
CONCLUSION: In conclusion, these result showed HADSCs could differentiate into chondrocytes-like cells, dependent on signaling induced by TGF-β3 and chondrocytes. This is a promising result and showed that HADSCs is a potential source for future microtia repair. The technique of co-culture is a positive way forward to assist the microtia tissue. OBJECTIVE: Reconstructive surgery for the repair of microtia still remains the greatest challenge among the surgeons...
November 30, 2016: Acta Oto-laryngologica
https://www.readbyqxmd.com/read/27882013/effect-of-half-adult-dose-of-oral-rifampicin-300mg-in-patients-with-idiopathic-central-serous-chorioretinopathy
#3
Muhammad Saim Khan, Murtaza Sameen, Arshad Ali Lodhi, Munawar Ahmed, Noman Ahmed, Mustafa Kamal, Sameen Afzal Junejo
OBJECTIVES: To evaluate the effect of half adult dose of oral Rifampicin on mean change in best corrected visual acuity and central macular thickness in patients with central serous chorioretinopathy. METHODS: Thirty-eight eyes of 31 patients with idiopathic central serous chorioretinopathy (CSCR) were registered. Unaided Visual acuity, best corrected visual acuity was documented and detailed slit lamp examination along with dilated ophthalmoscopy was performed...
September 2016: Pakistan Journal of Medical Sciences Quarterly
https://www.readbyqxmd.com/read/27881277/impact-of-health-policy-changes-on-trends-in-the-pharmaceutical-market-in-turkey
#4
Esra Safak Yılmaz, Güvenç Koçkaya, Fatma Betül Yenilmez, Mete Saylan, Mehtap Tatar, Akif Akbulat, Hakkı Gürsöz, Saim Kerman
BACKGROUND: The implementation phase of the Turkish Health Transformation Program (HTP) began in 2003, with the aim of organizing, financing, and delivering health care services effectively, efficiently, and equally. The HTP impacted all clinical and economic outcomes of health, including pharmaceutical sales, by improving access to health services. OBJECTIVES: To understand the impact of five selected major policy changes that made an impact on supply, demand, or price in the pharmaceutical market between 1998 and 2012...
September 2016: Value in Health Regional Issues
https://www.readbyqxmd.com/read/27863642/tissue-engineered-trachea-a-review
#5
REVIEW
Jia Xian Law, Ling Ling Liau, Bin Saim Aminuddin, Bt Hj Idrus Ruszymah
Tracheal replacement is performed after resection of a portion of the trachea that was impossible to reconnect via direct anastomosis. A tissue-engineered trachea is one of the available options that offer many advantages compared to other types of graft. Fabrication of a functional tissue-engineered trachea for grafting is very challenging, as it is a complex organ with important components, including cartilage, epithelium and vasculature. A number of studies have been reported on the preparation of a graftable trachea...
December 2016: International Journal of Pediatric Otorhinolaryngology
https://www.readbyqxmd.com/read/27854521/the-relationship-between-us-military-officer-leadership-behaviors-and-risk-of-sexual-assault-of-reserve-national-guard-and-active-component-servicewomen-in-nondeployed-locations
#6
Anne G Sadler, Michelle A Mengeling, Brenda M Booth, Amy M J O'Shea, James C Torner
OBJECTIVES: To determine if military leader behaviors are associated with active component and Reserve-National Guard servicewomen's risk of sexual assault in the military (SAIM) for nondeployed locations. METHODS: A community sample of 1337 Operation Enduring Freedom and Operation Iraqi Freedom-era Army and Air Force servicewomen completed telephone interviews (March 2010-December 2011) querying sociodemographic and military characteristics, sexual assault histories, and leader behaviors...
January 2017: American Journal of Public Health
https://www.readbyqxmd.com/read/27830871/assessment-of-femoral-neck-fractures-in-the-elderly-with-respect-to-morphology-and-mineral-density
#7
Hülya Çetin Sorkun, Arzu Hanım Yay, Esra Balcıoğlu, Saim Özdamar
BACKGROUND: Femoral neck fractures are among the major orthopedic problems seen in the elderly and the annual mortality rate is high. The Ca/P ratio can be used as an indicator of osteoporosis. The purpose of this study is to investigate the microarchitectural structure of the fractured regions of femoral head as well as bone mineral density in female and male patients. MATERIALS AND METHODS: The bone tissues taken from the fractured regions of 10 male and 9 female patients were examined with a scanning electron microscope...
November 10, 2016: Folia Morphologica (Warsz)
https://www.readbyqxmd.com/read/27816913/laser-acupuncture-treatment-improves-pain-and-functional-status-in-patients-with-subacromial-impingement-syndrome-a-randomized-double-blind-sham-controlled-study
#8
Sibel Kibar, Hatice Ecem Konak, Deniz Evcik, Saime Ay
OBJECTIVE:  The present study aims to determine the effect of laser acupuncture in patients with subacromial impingement syndrome (SAIS). DESIGN:  Randomized, double-blind, sham-controlled study. SETTING:  Physical medicine and rehabilitation outpatient clinic. SUBJECTS:  A total 73 patients with SAIS were randomly assigned into a treatment group (n = 36) and a control group (n = 37). METHODS : The treatment group received laser acupuncture, and the control group received sham laser acupuncture...
November 5, 2016: Pain Medicine: the Official Journal of the American Academy of Pain Medicine
https://www.readbyqxmd.com/read/27793541/comparison-of-culture-and-pcr-methods-in-the-diagnosis-of-bacterial-meningitis
#9
Emel Ödemiş Başpınar, Saim Dayan, Muhammed Bekçibaşı, Recep Tekin, Celal Ayaz, Özcan Deveci, Salih Hoşoğlu
Our aim in this study is to compare the standard culture method with the multiplex PCR and the Speed-Oligo(®) Bacterial Meningitis Test (SO-BMT) - a hybridization-based molecular test method - during the CSF examination of the patients with the pre-diagnosis of acute bacterial meningitis. For the purposes of this study, patients with acute bacterial meningitis treated at the Dicle University Medical Faculty Hospital, Infectious Diseases and Clinical Microbiology Clinic between December 2009 and April 2012 were retrospectively evaluated...
October 6, 2016: Brazilian Journal of Microbiology: [publication of the Brazilian Society for Microbiology]
https://www.readbyqxmd.com/read/27743514/investigation-of-factors-affecting-frequency-of-intestinal-parasites-in-primary-school-students-in-an-urban-region-in-turkey
#10
İnci Arıkan, Aynur Gülcan, Saime Ergen Dıbeklıoğlu
AIM: The aim of the study was to determine the incidence of intestinal parasitic diseases (IPD) and associated factors in primary school students and to assess the knowledge and practices of mothers about these diseases. METHODS: This is a cross-sectional study carried out in January-March 2014 in 471 students aged 5-11 years, studying at 3 schools randomly selected from the city centre regions with different socioeconomic levels. Stratified sampling method was used in the present study and the data were collected in two stages...
September 2016: Central European Journal of Public Health
https://www.readbyqxmd.com/read/27689939/three-dimensional-direct-cell-bioprinting-for-tissue-engineering
#11
Saime Burce Ozler, Ezgi Bakirci, Can Kucukgul, Bahattin Koc
Bioprinting is a relatively new technology where living cells with or without biomaterials are printed layer-by-layer in order to create three-dimensional (3D) living structures. In this article, novel bioprinting methodologies are developed to fabricate 3D biological structures directly from computer models using live multicellular aggregates. Multicellular aggregates made out of at least two cell types from fibroblast, endothelial and smooth muscle cells are prepared and optimized. A novel bioprinting approach is proposed in order to continuously extrude cylindrical multicellular aggregates through the bioprinter's glass microcapillaries...
September 30, 2016: Journal of Biomedical Materials Research. Part B, Applied Biomaterials
https://www.readbyqxmd.com/read/27671180/optic-nerve-sheath-diameter-on-sonography-in-idiopathic-intracranial-hypertension-versus-normal
#12
Hina Rehman, Muhammad Saim Khan, Muhammad Nafees, Attique Ur Rehman, Asad Habib
OBJECTIVE: To compare the mean optic nerve sheath diameter (ONSD) in patients with idiopathic intracranial hypertension (IIH) versus normal healthy individuals using B-scan ultrasonography as diagnostic tool. STUDY DESIGN: Cross-sectional analytical study. PLACE AND DURATION OF STUDY: Armed Forces Institute of Radiology and Imaging, Rawalpindi, Pakistan, from June to December 2015. METHODOLOGY: Participants aged 30 - 50 years were divided into two groups...
September 2016: Journal of the College of Physicians and Surgeons—Pakistan: JCPSP
https://www.readbyqxmd.com/read/27668527/the-effect-of-infliximab-on-intestinal-anastomosis-healing-in-rats
#13
Oktay Karaköse, Hüseyin Eken, Ali Naki Ulusoy, Hüseyin Koray Topgül, Mehmet Bilgin, Saim Savaş Yürüker, Mustafa Yavuz Gülbahar
Intestinal anastomosis healing is a complex physiological process in which many local and systemic factors play a role. One of the significant cytokines in this process is TNF-α. Infliximab is a chimeric monoclonal antibody which binds to TNF-α with high affinity. Although this agent is used in ulcerative colitis and Crohn's disease, intestinal surgery may be required in these patients. In this study it was aimed to determine whether or not there was any negative effect of preoperative single dose infliximab treatment on intestinal anastomosis healing...
2016: Prague Medical Report
https://www.readbyqxmd.com/read/27665332/hypertrophic-cardiomyopathy-with-jeune-syndrome-the-first-reported-case
#14
Osman Güvenç, Saime Sündüs Uygun, Derya Çimen, Eyüp Aslan, Ali Annagür
Jeune syndrome (Asphyxiating thoracic dysplasia) is a rare dystrophy of the skeleton, inherited as an autosomal recessive condition. Patients develop a narrowed thorax, rhizomelic dwarfism, and hepatic, renal, and pancreatic abnormalities. High rates of pulmonary hypoplasia and pulmonary hypertension have been reported. Some patients die in early stages of life due to respiratory failure. The case of a patient referred with a history of severe asphyxiating birth, who had been diagnosed with Jeune syndrome and later hypertrophic cardiomyopathy (HCM) upon echocardiographic examination is described in the present report...
September 2016: Türk Kardiyoloji Derneği Arşivi: Türk Kardiyoloji Derneğinin Yayın Organıdır
https://www.readbyqxmd.com/read/27648049/corneal-collagen-cross-linking-cxl-in-treatment-of-pseudophakic-bullous-keratopathy
#15
Muhammad Saim Khan, Imran Basit, Mazhar Ishaq, Tariq Shakoor, Amer Yaqub, Rana Intisar
OBJECTIVE: To determine mean change in visual acuity, central corneal thickness and symptoms in patients with pseudophakic bullous keratopathy after treatment with corneal collagen crosslinking. METHODS: This quasi experimental study was conducted at Armed Forces Institute of Ophthalmology, Rawalpindi, Pakistan from April 2015 to Nov 2015. A total of 24 eyes of 24 patients were included in the study. Visual symptoms were graded in five grades (Grade 1-5), Grade-1 being very mild with decreased vision only while patients with all five symptoms (decreased vision, foreign body sensations, pain, watering and photophobia) were graded as Grade-5...
July 2016: Pakistan Journal of Medical Sciences Quarterly
https://www.readbyqxmd.com/read/27595770/facile-synthesis-of-three-dimensional-pt-tio2-nano-networks-a-highly-active-catalyst-for-the-hydrolytic-dehydrogenation-of-ammonia-borane
#16
Mohammad Aref Khalily, Hamit Eren, Serdar Akbayrak, Hepi Hari Susapto, Necmi Biyikli, Saim Özkar, Mustafa O Guler
Three-dimensional (3D) porous metal and metal oxide nanostructures have received considerable interest because organization of inorganic materials into 3D nanomaterials holds extraordinary properties such as low density, high porosity, and high surface area. Supramolecular self-assembled peptide nanostructures were exploited as an organic template for catalytic 3D Pt-TiO2 nano-network fabrication. A 3D peptide nanofiber aerogel was conformally coated with TiO2 by atomic layer deposition (ALD) with angstrom-level thickness precision...
September 26, 2016: Angewandte Chemie
https://www.readbyqxmd.com/read/27593799/computerized-tomography-guided-stereotactic-biopsy-of-intracranial-lesions-report-of-consecutive-500-cases
#17
Songül Meltem Can, Osman Nuri Türkmenoğlu, Canan Tanik, Ender Uysal, Barış Özöner, Saime Ayça Kaldirimoğlu, Ahmet Murat Müslüman, Adem Yilmaz, Halit Çavuşoğlu, Çiçek Bayindir, Yunus Aydin
AIM: CT-guided stereotactic brain biopsy has been performed in our clinic since March 1998. In this prospective study, we examined the patient data undergoing stereotactic biopsy and the results of biopsies in consecutive 500 patients. MATERIAL AND METHODS: Between the dates of March 1998 and January 2015, CT guided stereotactic biopsies were performed by using the Leksell stereotactic frame system (Elekta Instruments EU, Sweden) in 500 patients. A total of 512 procedures were performed in patients consisting of 184 females (36...
January 25, 2016: Turkish Neurosurgery
https://www.readbyqxmd.com/read/27540320/recent-updates-in-neuroprotective-and-neuroregenerative-potential-of-centella-asiatica
#18
REVIEW
Yogeswaran Lokanathan, Norazzila Omar, Nur Nabilah Ahmad Puzi, Aminuddin Saim, Ruszymah Hj Idrus
Centella asiatica, locally well known in Malaysia as pegaga, is a traditional herb that has been used widely in Ayurvedic medicine, traditional Chinese medicine, and in the traditional medicine of other Southeast Asian countries including Malaysia. Although consumption of the plant is indicated for various illnesses, its potential neuroprotective properties have been well studied and documented. In addition to past studies, recent studies also discovered and/or reconfirmed that C. asiatica acts as an antioxidant, reducing the effect of oxidative stress in vitro and in vivo...
January 2016: Malaysian Journal of Medical Sciences: MJMS
https://www.readbyqxmd.com/read/27516740/introduction-and-utilization-of-high-priced-hcv-medicines-across-europe-implications-for-the-future
#19
Winnie de Bruijn, Cristina Ibáñez, Pia Frisk, Hanne Bak Pedersen, Ali Alkan, Patricia Vella Bonanno, Ljiljana S Brkičić, Anna Bucsics, Guillaume Dedet, Jaran Eriksen, Joseph O Fadare, Jurij Fürst, Gisselle Gallego, Isabella P Godói, Augusto A Guerra Júnior, Hakkı Gürsöz, Saira Jan, Jan Jones, Roberta Joppi, Saim Kerman, Ott Laius, Newman Madzikwa, Einar Magnússon, Mojca Maticic, Vanda Markovic-Pekovic, Amos Massele, Olayinka Ogunleye, Aisling O'Leary, Jutta Piessnegger, Catherine Sermet, Steven Simoens, Celda Tiroyakgosi, Ilse Truter, Magnus Thyberg, Kristina Tomekova, Magdalena Wladysiuk, Sotiris Vandoros, Elif H Vural, Corinne Zara, Brian Godman
BACKGROUND: Infection with the Hepatitis C Virus (HCV) is a widespread transmittable disease with a diagnosed prevalence of 2.0%. Fortunately, it is now curable in most patients. Sales of medicines to treat HCV infection grew 2.7% per year between 2004 and 2011, enhanced by the launch of the protease inhibitors (PIs) boceprevir (BCV) and telaprevir (TVR) in addition to ribavirin and pegylated interferon (pegIFN). Costs will continue to rise with new treatments including sofosbuvir, which now include interferon free regimens...
2016: Frontiers in Pharmacology
https://www.readbyqxmd.com/read/27513257/the-effect-of-addition-of-ketamine-to-lidocaine-on-postoperative-pain-in-rhinoplasties
#20
Mukadder Şanli, Nurçin Gülhaş, Bilge Türk Bilen, Gülay Erdoğan Kayhan, Muharrem Uçar, Ahmet Hamdi Aytekin, Saim Yoloğlu
BACKGROUND/AIM: The objective of this study was to examine the effect of addition of subanesthetic doses of ketamine to an epinephrine-lidocaine solution on postoperative pain, analgesic use, and patient comfort during rhinoplasties. MATERIALS AND METHODS: Ninety patients were randomly divided into three groups: Group L, lidocaine with epinephrine; Group K, lidocaine with epinephrine plus ketamine; and Group S (control group), physiological saline solution with epinephrine...
2016: Turkish Journal of Medical Sciences
keyword
keyword
70864
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"