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https://www.readbyqxmd.com/read/27910751/recent-advances-in-pharmacotherapeutic-paradigm-of-mild-to-recalcitrant-atopic-dermatitis
#1
Zahid Hussain, Shariza Sahudin, Hnin Ei Thu, Ahmad Nazrun Shuid, Syed Nasir Abbas Bukhari, Endang Kumolosasi
Atopic dermatitis (AD) is a common, chronic skin inflammatory disorder characterized by perivascular infiltration of immunoglobulin E (IgE), T lymphocytes, and mast cells. The key factors responsible for the pathophysiology of this disease are immunological disorders and defects in epidermal barrier properties. Pruritus, intense itching, psychological stress, deprived physical and mental performance, and sleep disturbance are the hallmark features of this dermatological disorder. Preventive interventions such as educational programs, avoidance of allergens, and exclusive care toward the skin could play a partial role in suppressing the symptoms...
2016: Critical Reviews in Therapeutic Drug Carrier Systems
https://www.readbyqxmd.com/read/27900739/-evidence-based-knowledge-translation-from-scientific-evidence-to-clinical-nursing-practice
#2
Kee-Hsin Chen, Ching-Chiu Kao, Chiehfeng Chen
In 1992, Gordon Guyatt coined the term "evidence-based medicine", which has since attracted worldwide attention. In 2007, the Institute of Medicine's Roundtable on Evidence-Based Medicine set the goal that 90% of clinical decisions would be supported by accurate, timely, and up-to-date clinical information and would reflect the best available evidence by 2020. However, the chasm between knowing and doing remains palpable. In 2000, the Canadian Institute of Health Research applied the term "knowledge translation" to describe the bridge that is necessary to cross the gap between research knowledge and clinical practice...
December 2016: Hu Li za Zhi the Journal of Nursing
https://www.readbyqxmd.com/read/27893918/breast-milk-collection-and-storage-in-the-neonatal-intensive-care-unit-nurses-knowledge-practice-and-perceived-barriers
#3
Huda Falah Gharaibeh, Nihaya Al-Sheyab, Shefa Yousef Malkawi
BACKGROUND: Temporary storage of human milk under appropriate conditions encourages prolonged breast-feeding. PURPOSE: This study aimed to assess neonatal nurses' knowledge and practice, as well as barriers, related to breast milk collection and storage and to investigate the association between nurses' knowledge and practice and other variables. METHOD: A cross-sectional design was used. Consecutive samplings of 75 nurses were recruited. The questions were based on a literature review of guidelines for collecting and storing breast milk from various sources, such as the Centers for Disease Control and Prevention and the Academy of Breastfeeding Medicine...
December 1, 2016: Journal of Continuing Education in Nursing
https://www.readbyqxmd.com/read/27875451/developing-a-framework-to-help-bedside-nurses-bring-about-change
#4
Jordan S Porter, Kelley A Strout
: Nurses across all care settings and experience levels are being called upon to lead. In a 2011 report, The Future of Nursing: Leading Change, Advancing Health, the Institute of Medicine examined the ways nurses could more fully apply their knowledge of direct patient care to address the increasing demands placed on the health care system since the passage of the Affordable Care Act. The report asked: "What roles can nursing assume to address the increasing demand for safe, high-quality, and effective health care services?"Multiple variables influence a nurse's ability to assume a leadership role, and multiple barriers to these roles continue to exist...
December 2016: American Journal of Nursing
https://www.readbyqxmd.com/read/27869877/-computerized-decision-support-systems-ebm-at-the-bedside
#5
Matteo Capobussi, Rita Banzi, Lorenzo Moja, Stefanos Bonovas, Marien González-Lorenzo, Elisa Giulia Liberati, Hernan Polo Friz, Oriana Nanni, Massimo Mangia, Francesca Ruggiero
INTRODUCTION: One of the aims of Evidence-Based Medicine is to improve quality and appropriateness of care by the expedition of the knowledge transfer process. Computerized Decision Support Systems (CDSSs) are computer programs that provide alerts to the prescribing doctor directly at the moment of medical examination. In fact, alerts are integrated within the single patient electronic health record. CDSS based on the best available and updated evidence and guidelines may be an efficient tool to facilitate the transfer of the latest results from clinical research directly at the bedside, thus supporting decision-making...
November 2016: Recenti Progressi in Medicina
https://www.readbyqxmd.com/read/27857272/clinical-approach-for-patient-centered-physical-activity-assessment-and-interventions
#6
Allica Austin, Shamsha Damani, Therese Bevers
BACKGROUND: A physical activity algorithm for adults was created with the aim of reducing patients' barriers for physical activity by providing healthcare professionals with a standardized process to guide clinical discussions on physical activity to reduce the risk of chronic diseases, specifically cancer. OBJECTIVES: The physical activity algorithm was designed as an applicable process that could be adopted in many professional settings with the mission to provide relevant, safe, and appropriate physical activity interventions...
December 1, 2016: Clinical Journal of Oncology Nursing
https://www.readbyqxmd.com/read/27785350/training-emergency-physicians-in-sex-and-gender-based-medicine-assessing-attitudes-of-program-directors-and-residency-graduates
#7
Tracy E Madsen, Alyson J McGregor
BACKGROUND: Sex and gender influence disease presentation, treatment, healthcare access, and long-term outcomes. It is uncertain to what extent sex- and gender-based medicine (SGBM) content has been integrated into emergency medicine (EM) residency curricula. We aimed to determine if SGBM is being taught in EM residency training, if EM residency program directors (PDs) declare SGBM a curriculum priority, and if recent graduates (RGs) of EM residency programs declare SGBM as relevant to their practice...
2016: Biology of Sex Differences
https://www.readbyqxmd.com/read/27754281/hw-04-1-usefulness-of-big-data-in-clinical-research
#8
Rae Woong Park
Big data indicates the large and ever-increasing volumes of data adhere to the following 4Vs: volume (ever-increasing amount), velocity (quickly generated), variety (many different types), veracity (from trustable sources). The last decade has seen huge advances in the amount of data we routinely generate and collect in pretty much everything we do, as well as our ability to use technology to analyze and understand it. The routine operation of modern health care systems also produces an abundance of electronically stored data on an ongoing basis as a byproduct of clinical practice...
September 2016: Journal of Hypertension
https://www.readbyqxmd.com/read/27748248/implementation-of-sleep-and-circadian-science-recommendations-from-the-sleep-research-society-and-national-institutes-of-health-workshop
#9
Sairam Parthasarathy, Mary A Carskadon, Girardin Jean-Louis, Judith Owens, Adam Bramoweth, Daniel Combs, Lauren Hale, Elizabeth Harrison, Chantelle N Hart, Brant P Hasler, Sarah M Honaker, Elisabeth Hertenstein, Samuel Kuna, Clete Kushida, Jessica C Levenson, Caitlin Murray, Allan I Pack, Vivek Pillai, Kristi Pruiksma, Azizi Seixas, Patrick Strollo, Saurabh S Thosar, Natasha Williams, Daniel Buysse
A wealth of scientific knowledge is being generated in sleep and circadian science. In order for us to realize the return on investment for such scientific knowledge and to improve the health of the nation, we need to disseminate and implement research findings into practice. An implementation gap - termed a "quality chasm" by the Institutes of Medicine - separates the scientific knowledge we possess and the implementation of such knowledge into preventative interventions or healthcare treatments. It is frequently reported that a time lag of 17 years transpires before medical research reaches clinical practice...
October 10, 2016: Sleep
https://www.readbyqxmd.com/read/27735926/experiences-from-a-pilot-program-bringing-brca1-2-genetic-screening-to-theus-ashkenazi-jewish-population
#10
Chana Wiesman, Esther Rose, Allison Grant, Adam Zimilover, Susan Klugman, Nicole Schreiber-Agus
PURPOSE: The notion of offering population-based screening to the Ashkenazi Jewish (AJ) population for the BRCA1/2 founder mutations continues to gain support. A program called the BRCAcommunity initiative was designed to identify the benefits and barriers associated with implementing this screening in a clinical setting. METHODS: Interested AJ individuals were stratified into high-risk (HR) and low-risk (LR) groups based on self-reported cancer histories. Those at HR were offered traditional genetic counseling/testing; those at LR were offered group genetic counseling and subsidized AJ BRCA founder mutation testing...
October 13, 2016: Genetics in Medicine: Official Journal of the American College of Medical Genetics
https://www.readbyqxmd.com/read/27733918/novel-models-to-improve-access-to-medicines-for-chronic-diseases-in-south-africa-an-analysis-of-stakeholder-perspectives-on-community-based-distribution-models
#11
Bvudzai Priscilla Magadzire, Bruno Marchal, Kim Ward
BACKGROUND: The rising demand for chronic disease treatment and the barriers to accessing these medicines have led to the development of novel models for distributing medicines in South Africa's public sector, including distribution away from health centres, known as community-based distribution (CBD). In this article, we provide a typology of CBD models and outline perceived facilitators and barriers to their implementation using an adapted health systems framework with a view to analysing how future policy decisions on CBD could impact existing models and the health system as a whole...
2016: Journal of Pharmaceutical Policy and Practice
https://www.readbyqxmd.com/read/27720694/the-power-of-capturing-and-using-information-at-the-point-of-care
#12
William H Gruber, Adam C Powell, John B Torous
Historically, the process of scientific discovery and the process of clinical delivery have been poorly integrated. As a result of the Decade of Health Information Technology (2004-2014), many of the former barriers to capturing, processing, and retrieving medical information at the point of care have been surmounted. This change has the potential to both transform how new medical discoveries are made and how evidence-based medicine is put into practice. To illustrate the impact of this ongoing change, several examples are provided of institutions which have innovatively used information at the point of care...
October 6, 2016: Healthcare
https://www.readbyqxmd.com/read/27694289/preparing-dental-students-and-residents-to-overcome-internal-and-external-barriers-to-evidence-based-practice
#13
Brandon G Coleman, Thomas M Johnson, Kenneth J Erley, Richard Topolski, Michael Rethman, Douglas D Lancaster
In recent years, evidence-based dentistry has become the ideal for research, academia, and clinical practice. However, barriers to implementation are many, including the complexity of interpreting conflicting evidence as well as difficulties in accessing it. Furthermore, many proponents of evidence-based care seem to assume that good evidence consistently exists and that clinicians can and will objectively evaluate data so as to apply the best evidence to individual patients' needs. The authors argue that these shortcomings may mislead many clinicians and that students should be adequately prepared to cope with some of the more complex issues surrounding evidence-based practice...
October 2016: Journal of Dental Education
https://www.readbyqxmd.com/read/27670417/-the-horse-has-bolted-i-suspect-a-qualitative-study-of-clinicians-attitudes-and-perceptions-regarding-palliative-rehabilitation
#14
Fiona Runacres, Heidi Gregory, Anna Ugalde
BACKGROUND: Palliative care patients have numerous rehabilitation needs that increase with disease progression. Palliative rehabilitation practices and perceptions of palliative medicine physicians towards the role of rehabilitation are largely unstudied. AIM: To explore palliative medicine physicians' attitudes and perceptions towards rehabilitation delivered within inpatient palliative care units. DESIGN: Qualitative study utilizing semi-structured interviews...
September 26, 2016: Palliative Medicine
https://www.readbyqxmd.com/read/27658352/contemporary-evidence-based-practice-in-canadian-emergency-medical-services-a-vision-for-integrating-evidence-into-clinical-and-policy-decision-making
#15
Jan L Jensen, Andrew H Travers
Nationally, emphasis on the importance of evidence-based practice (EBP) in emergency medicine and emergency medical services (EMS) has continuously increased. However, meaningful incorporation of effective and sustainable EBP into clinical and administrative decision-making remains a challenge. We propose a vision for EBP in EMS: Canadian EMS clinicians and leaders will understand and use the best available evidence for clinical and administrative decision-making, to improve patient health outcomes, the capability and quality of EMS systems of care, and safety of patients and EMS professionals...
September 23, 2016: CJEM
https://www.readbyqxmd.com/read/27646803/society-of-behavioral-medicine-supports-implementation-of-high-quality-lung-cancer-screening-in-high-risk-populations
#16
Karriem S Watson, Amanda C Blok, Joanna Buscemi, Yamile Molina, Marian Fitzgibbon, Melissa A Simon, Lance Williams, Kameron Matthews, Jamie L Studts, Sarah E Lillie, Jamie S Ostroff, Lisa Carter-Harris, Robert A Winn
The Society of Behavioral Medicine (SBM) supports the United States Preventive Services Task Force (USPSTF) recommendation of low-dose computed tomography (LDCT) screening of the chest for eligible populations to reduce lung cancer mortality. Consistent with efforts to translate research findings into real-world settings, SBM encourages health-care providers and health-care systems to (1) integrate evidence-based tobacco treatment as an essential component of LDCT-based lung cancer screening, (2) examine the structural barriers that may impact screening uptake, and (3) incorporate shared decision-making as a clinical platform to facilitate consultations and engagement with individuals at high risk for lung cancer about the potential benefits and harms associated with participation in a lung cancer screening program...
December 2016: Translational Behavioral Medicine
https://www.readbyqxmd.com/read/27643278/hw-04-1-usefulness-of-big-data-in-clinical-research
#17
Rae Woong Park
Big data indicates the large and ever-increasing volumes of data adhere to the following 4Vs: volume (ever-increasing amount), velocity (quickly generated), variety (many different types), veracity (from trustable sources). The last decade has seen huge advances in the amount of data we routinely generate and collect in pretty much everything we do, as well as our ability to use technology to analyze and understand it. The routine operation of modern health care systems also produces an abundance of electronically stored data on an ongoing basis as a byproduct of clinical practice...
September 2016: Journal of Hypertension
https://www.readbyqxmd.com/read/27621161/hostility-during-training-historical-roots-of-primary-care-disparagement
#18
Joanna Veazey Brooks
PURPOSE: The environment during medical school has been shown to dissuade students from choosing primary care careers. The purpose of this study was (1) to explore how long-standing this hostility toward primary care is historically and (2) to understand the mechanisms through which the environment conveys disparagement of primary care to students. METHODS: The study is based on a qualitative analysis of 52 primary care physician oral histories. The data are from the Primary Care Oral History Collection, created by Fitzhugh Mullan and deposited in the National Library of Medicine...
September 2016: Annals of Family Medicine
https://www.readbyqxmd.com/read/27583994/the-gene-messenger-impact-project-an-innovative-genetics-continuing-education-strategy-for-primary-care-providers
#19
June C Carroll, Roland Grad, Judith E Allanson, Pierre Pluye, Joanne A Permaul, Nicholas Pimlott, Brenda J Wilson
INTRODUCTION: Primary care providers (PCP) will need to be integrally involved in the delivery of genomic medicine. The GenetiKit trial demonstrated effectiveness of a knowledge translation intervention on family physicians' (FP) genetics referral decision-making. Most wanted to continue receiving Gene Messengers (GM), evidence-based summaries of new genetic tests with primary care recommendations. Our objective was to determine the value of GMs as a continuing education (CE) strategy in genomic medicine for FPs...
2016: Journal of Continuing Education in the Health Professions
https://www.readbyqxmd.com/read/27532038/barriers-to-treatment-and-control-of-hypertension-among-hypertensive-participants-a-community-based-cross-sectional-mixed-method-study-in-municipalities-of-kathmandu-nepal
#20
Surya Devkota, Raja Ram Dhungana, Achyut Raj Pandey, Bihungum Bista, Savyata Panthi, Kartikesh Kumar Thakur, Ratna Mani Gajurel
INTRODUCTION: Despite the established evidence on benefits of controlling raised blood pressure and development of several guidelines on detection and management of hypertension, people often have untreated or uncontrolled hypertension. In this context, we undertook this study to identify the barriers existing in hypertension treatment and control in the municipalities of Kathmandu district in Nepal. METHODS: This was a community based, cross-sectional mixed method study conducted in the municipalities of Kathmandu district in Nepal between January and July 2015...
2016: Frontiers in Cardiovascular Medicine
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