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https://www.readbyqxmd.com/read/27904860/interventional-therapy-for-pancreatic-cancer
#1
REVIEW
Jianwei Zhu, Zhendong Jin
BACKGROUND: Palliative therapy and primarily chemoradiotherapy are the mainstream treatments in patients with locally advanced or metastatic pancreatic cancer (PC). Conventional endoscopy and endoscopic ultrasound (EUS)-guided interventional therapy has emerged as an important procedure for PC management. In this review, the progress in conventional endoscopy and EUS for PC management is discussed. SUMMARY: For local palliative therapy against PC, EUS-guided fine needle injection (FNI) could deliver different kinds of agents, such as radioactive seeds and fiducials...
October 2016: Gastrointestinal Tumors
https://www.readbyqxmd.com/read/27904252/hemobilia
#2
REVIEW
Rakesh Navuluri
Hemobilia is a rare source of upper gastrointestinal bleeding, though the incidence is increasing along with the rise in minimally invasive biliary interventions. Prompt diagnosis and treatment rests on having appropriate clinical suspicion which should be based on the patient's presenting signs and symptoms, as well as history including recent instrumentation. Endoscopy should be reserved for cases of upper gastrointestinal bleeding with low suspicion for hemobilia. Interventional radiology may be the first-line diagnostic and therapeutic option for patients with a high suspicion of hemobilia...
December 2016: Seminars in Interventional Radiology
https://www.readbyqxmd.com/read/27895378/intravesical-foreign-body-tertiary-care-center-experience-from-pakistan
#3
Hussam Uddin Soomro, Imran Jalbani, Nuzhat Faruqui
Foreign body in bladder is relatively uncommon condition with variable presentations. Literature is limited to case reports and small series from region. Therefore, we planned this study to review our experience regarding intravesical foreign body. This retrospective study was conducted at the Aga Khan University Hospital, Karachi, and comprised 14 patients having intravesical foreign bodies from March 1989 to March 2013. Demographics, presentation, mode of insertion, type of foreign body and management were noted...
October 2016: JPMA. the Journal of the Pakistan Medical Association
https://www.readbyqxmd.com/read/27886406/disrupted-pancreatic-duct-treated-with-a-combination-of-endoscopic-cystoduodenostomy-and-pancreatic-duct-fistualization-through-a-pseudocyst-wall-via-lumen-apposing-metal-stent
#4
Robert M Wilechansky, Ali S Khan, Amrita Sethi
The management of disconnected pancreatic duct syndrome is complex and is increasingly approached using emerging endoscopic techniques. Here, we present a case of recurrent pancreatitis in an elderly woman complicated by pseudocyst formation and complete pancreatic duct disruption. Her condition was treated with a novel combination of transpapillary stenting and cystduodenostomy in which a pancreatic duct stent was placed into an opening in the pseudocyst wall via lumen-apposing metal stent. This allowed for effective drainage into the gastrointestinal tract and resolution of duct disruption...
November 25, 2016: Digestive Endoscopy: Official Journal of the Japan Gastroenterological Endoscopy Society
https://www.readbyqxmd.com/read/27882097/effect-of-a-paclitaxel-eluting-metallic-stent-on-rabbit-esophagus
#5
Yin Zhang, Ying Gao, Jianping Chen, Limei Ma, Li Liu, Xiang Wang, Zhining Fan
The use of self-expanding metallic stents (SEMS) is the current treatment of choice for malignant gastrointestinal obstructions. A paclitaxel-eluting metallic SEMS (PEMS) may have an antitumor effect on esophageal tissue. PEMS with 10% paclitaxel or conventional SEMS were inserted into the lower esophagus of rabbits. Following the insertion of the stents for 1, 2, 4 and 6 weeks, the rabbits were sacrificed and the status of the stent insertion was examined, as well as any macroscopic or microscopic mucosal changes in the esophageal tissue...
November 2016: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/27874149/gastroesophageal-stenting-for-the-management-of-post-sleeve-gastrectomy-leak-a-single-institution-experience
#6
Noha Guzaiz, Mohammad Arabi, Azzam Khankan, Refaat Salman, Mohammed Al-Toki, Shahbaz Qazi, Abdulmohsin Alzakari, Mohammad Al-Moaiqel
OBJECTIVES: To retrospectively evaluate the effectiveness of gastroesophageal stenting for post sleeve gastrectomy staple line leaks using removable self-expandable stents. METHODS: Between April 2012 and June 2015, 12 consecutive patients (6 males) with mean age of 34 years (21-38 years) presented with staple line leak 1-8 weeks after the operation (mean 2.8 weeks). Patients underwent gastroesophageal stenting by interventional radiology. A total of 23 stents were deployed with mean length of 17...
December 2016: Saudi Medical Journal
https://www.readbyqxmd.com/read/27846161/endoscopic-stenting-with-the-over-the-scope-technique-our-experience-with-11-consecutive-patients
#7
Massimiliano Mutignani, Stefanos Dokas, Edoardo Forti, Francesco Pugliese, Raffaele Manta, Lorenzo Dioscoridi
BACKGROUND: Endoscopic stenting is widely used to manage benign and malignant strictures, postoperative stenoses, or anastomotic leaks and fistulas. MATERIALS AND METHODS: However, Over the Wire delivery systems are generally short and quite stiff, and therefore, cannot reach distal parts of the gastrointestinal tract or cross severely angulated strictures. In such cases, we used the Over-the-Scope stenting (OTSS) technique to deliver and deploy endoscopically large-bore fully covered stents...
November 14, 2016: Surgical Laparoscopy, Endoscopy & Percutaneous Techniques
https://www.readbyqxmd.com/read/27833405/efficacy-of-retrievable-metallic-stent-with-fixation-string-for-benign-stricture-after-upper-gastrointestinal-surgery
#8
Jeong-Eun Kim, Hyo-Cheol Kim, Myungsu Lee, Saebeom Hur, Minuk Kim, Sang Hwan Lee, Soo Buem Cho, Chan Sun Kim, Joon Koo Han
OBJECTIVE: To determine the efficacy of retrievable metallic stent with fixation string for benign anastomotic stricture after upper gastrointestinal (UGI) surgery. MATERIALS AND METHODS: From June 2009 to May 2015, a total of 56 retrievable metallic stents with fixation string were placed under fluoroscopy guidance in 42 patients who were diagnosed with benign anastomotic stricture after UGI surgery. Clinical success was defined as achieving normal regular diet (NRD)...
November 2016: Korean Journal of Radiology: Official Journal of the Korean Radiological Society
https://www.readbyqxmd.com/read/27826062/characteristics-aetiology-antimicrobial-resistance-and-outcomes-of-bacteraemic-cholangitis-in-patients-with-solid-tumours-a-prospective-cohort-study
#9
C Royo-Cebrecos, C Gudiol, J García, F Tubau, J Laporte, C Ardanuy, M Antonio, M Marin, J B Gornals, J Carratalà
OBJECTIVES: To asses the clinical features, aetiology, antimicrobial resistance and outcomes of bacteraemic cholangitis in patients with solid tumours (ST). METHODS: All consecutive episodes of bacteraemia in hospitalized patients were prospectively analysed (2006-2015). RESULTS: Of 1852 episodes of bacteraemia, 750 involved patients with ST. Among them, 173 episodes (23%) were due to cholangitis. The most frequent neoplasms were hepato-biliary-pancreatic tumours (68...
November 5, 2016: Journal of Infection
https://www.readbyqxmd.com/read/27816341/stroke-prevention
#10
Clothilde Isabel, David Calvet, Jean-Louis Mas
Patients who have had a stroke are at high risk for recurrent stroke, myocardial infarction, and vascular death. Prevention of these events should be initiated promptly after stroke, because many recurrent events occur early, and should be tailored to the precise cause of stroke, which may require specific treatment. Lifestyle advice including abstinence from smoking, regular exercise, Mediterranean-style diet, and reduction of salt intake and alcohol consumption are recommended for all patients with stroke...
November 3, 2016: La Presse Médicale
https://www.readbyqxmd.com/read/27803736/the-location-of-obstruction-predicts-stent-occlusion-in-malignant-gastric-outlet-obstruction
#11
Douglas Grunwald, Jonah Cohen, Anthony Bartley, Jennifer Sheridan, Ram Chuttani, Mandeep S Sawhney, Douglas K Pleskow, Tyler M Berzin, Meir Mizrahi
BACKGROUND: Gastric outlet obstruction (GOO) can occur with locally invasive or metastatic cancer involving the upper gastrointestinal tract at the pylorus or the duodenum. Endoscopic management with self-expanding metal stents (SEMSs) is often the preferred palliative approach. Stent occlusion is a common reason for failure and reintervention. We set out to determine whether the location of the malignant obstruction is associated with the angulation of the stent and can predict stent occlusion...
November 2016: Therapeutic Advances in Gastroenterology
https://www.readbyqxmd.com/read/27781044/clopidogrel-plus-aspirin-for-symptomatic-intracranial-atherosclerotic-stenosis-a-pilot-study
#12
Tareq Kass-Hout, Melanie Winningham, Omar Kass-Hout, Laura Henriquez, Frank Tong, Jacques Dion, Michael Cawley, Samir Belagaje, Michael Frankel, Aaron Anderson, Fadi Nahab
BACKGROUND AND PURPOSE: There are limited data on the optimal duration of dual antiplatelet therapy for secondary stroke prevention in patients with symptomatic intracranial atherosclerotic disease. METHODS: Consecutive patients presenting with high-grade (70-99%) symptomatic intracranial stenosis from January 1, 2011, to December 31, 2013, and evaluated within 30 days of the index event were eligible for this analysis. All patients underwent treatment with aspirin plus clopidogrel for a target duration of 12 months along with aggressive medical management based on the Stenting and Aggressive Medical Management for Preventing Recurrent Stroke in Intracranial Stenosis (SAMMPRIS) protocol; all patients were given gastrointestinal prophylaxis for the duration of their aspirin and clopidogrel treatment...
September 2016: Interventional Neurology
https://www.readbyqxmd.com/read/27770082/endovascular-reconstruction-of-extrahepatic-portal-vein-in-noncirrhotic-and-nonmalignant-chronic-portal-vein-thrombosis-secondary-to-an-iatrogenic-stenotic-lesion
#13
Manuel Guerrero-Hernandez, Carlos A Hinojosa, Javier E Anaya-Ayala, Erika Elenes, Aldo Torre
Portal vein (PV) thrombosis (PVT) in the absence of liver disease or thrombophilia is rare. We report a 57-year-old male with a history of stage 3 chronic kidney disease who presented at the emergency department 18 months after abdominal surgery with progressive abdominal pain and distention. Computed tomography revealed PVT with multiple collaterals and moderate ascites. He had undergone partial gastrectomy and gastrojejunal anastomosis at an outside facility for gastrointestinal stromal tumors that caused an iatrogenic stenotic lesion in the PV...
October 20, 2016: Vascular and Endovascular Surgery
https://www.readbyqxmd.com/read/27723988/-late-complications-of-liver-cirrhosis-management-of-gastrointestinal-bleeding-in-the-presence-of-portal-hypertension
#14
Václav Hejda
Cirrhosis is the end stage of progressive development of different liver diseases and is associated with significant morbidity and mortality rates. Cirrhosis is associated with a number of potential complications, in particular with development of portal hypertension. Portal hypertension with the production of ascites, hepatic and gastric varices bleeding in the upper part of the gastrointestinal tract, presents the breakpoint in the natural course of cirrhosis, and it is associated with a considerably worse prognosis of patients, with a dramatically increased risk of mortality...
2016: Vnitr̆ní Lékar̆ství
https://www.readbyqxmd.com/read/27688214/the-clinical-utility-of-over-the-scope-clip-for-the-treatment-of-gastrointestinal-defects
#15
Ido Mizrahi, Rana Eltawil, Nadav Haim, Sami A Chadi, Bo Shen, Tolga Erim, Giovanna DaSilva, Steven D Wexner
BACKGROUND: The over-the-scope clip (OTSC) is a novel endoscopic tool that enables non-surgical management of gastrointestinal (GI) defects. The aim of this study was to report our experience with OTSC for patients with GI defects. METHODS: A prospectively maintained IRB-approved institutional database was queried for all patients treated with OTSC from 2012 to 2015. Primary outcome was the clinical success of the OTSC for the individual indication. Secondary outcome was the number of additional procedures needed following OTSC...
September 29, 2016: Journal of Gastrointestinal Surgery: Official Journal of the Society for Surgery of the Alimentary Tract
https://www.readbyqxmd.com/read/27684285/new-generation-of-gold-nanoshell-coated-esophageal-stent-preparation-and-biomedical-applications
#16
Jibin Song, Hao Hu, Chao Jian, Kaichun Wu, Xiaoyuan Chen
Esophageal cancer is one of the six most common cancers in the world, constituting ∼7% of the gastrointestinal cancers. Esophageal stents can be inserted into the esophagus to open the pathway as a palliative treatment for advanced esophageal cancer. For the treatment of esophageal cancer, a series of anticancer drug-loaded stents such as paclitaxel or 5-fluorouracil/esophageal stent combinations have been prepared by covering a nitinol stent with a polymer or hydrogel shell. For the first time, we developed a gold nanoshell (AuNS)-coated stent with high photothermal efficiency and used in the repetitive photothermal therapy of esophageal cancer...
October 5, 2016: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/27671449/sarcoidosis-associated-aortoesophageal-fistula-multistage-interdisciplinary-surgical-therapy-for-a-rare-and-life-threatening-condition
#17
A Gombert, J Grommes, G Schick, M Binnebösel, C Klink, M J Jacobs, D Kotelis
OBJECTIVE: Aortoesophageal fistulas are rare and life-threatening conditions. Till now, an association between an aortoesophageal fistula and sarcoidoisis has not been reported yet. The aim of this report is to demonstrate a case of aortoesophageal fistula (AEF) secondary to sarcoidosis and its multistage interdisciplinary surgical therapy. CASE REPORT: A 66-year-old male was diagnosed with sarcoidosis in 2014. He has been treated with glucocorticoids since then and no severe health restrictions due the disease had occurred...
September 23, 2016: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/27648272/the-forgotten-biliary-stent-an-unusual-cause-of-diarrhea
#18
Harkiran Sran, Joseph Sebastian, Samer Doughan
This case highlights the possible complications of biliary stents, which may include migration and impaction in the gastrointestinal tract. It also emphasizes the need for a robust follow-up system after stent placement, to minimize the risks and possible sequelae of a forgotten stent.
September 2016: Clinical Case Reports
https://www.readbyqxmd.com/read/27648164/open-abdomen-in-gastrointestinal-surgery-which-technique-is-the-best-for-temporary-closure-during-damage-control
#19
Marcelo A F Ribeiro Junior, Emily Alves Barros, Sabrina Marques de Carvalho, Vinicius Pereira Nascimento, José Cruvinel Neto, Alexandre Zanchenko Fonseca
AIM: To compare the 3 main techniques of temporary closure of the abdominal cavity, vacuum assisted closure (vacuum-assisted closure therapy - VAC), Bogota bag and Barker technique, in damage control surgery. METHODS: After systematic review of the literature, 33 articles were selected to compare the efficiency of the three procedures. Criteria such as cost, infections, capacity of reconstruction of the abdominal wall, diseases associated with the technique, among others were analyzed...
August 27, 2016: World Journal of Gastrointestinal Surgery
https://www.readbyqxmd.com/read/27648158/surgical-palliation-of-gastric-outlet-obstruction-in-advanced-malignancy
#20
REVIEW
Brittany A Potz, Thomas J Miner
Gastric outlet obstruction (GOO) is a common problem associated with advanced malignancies of the upper gastrointestinal tract. Palliative treatment of patients' symptoms who present with GOO is an important aspect of their care. Surgical palliation of malignancy is defined as a procedure performed with the intention of relieving symptoms caused by an advanced malignancy or improving quality of life. Palliative treatment for GOO includes operative (open and laparoscopic gastrojejunostomy) and non-operative (endoscopic stenting) options...
August 27, 2016: World Journal of Gastrointestinal Surgery
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