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https://www.readbyqxmd.com/read/29449588/spectral-features-of-the-tunneling-induced-transparency-and-the-autler-townes-doublet-and-triplet-in-a-triple-quantum-dot
#1
Xiao-Qing Luo, Zeng-Zhao Li, Jun Jing, Wei Xiong, Tie-Fu Li, Ting Yu
We theoretically investigate the spectral features of tunneling-induced transparency (TIT) and Autler-Townes (AT) doublet and triplet in a triple-quantum-dot system. By analyzing the eigenenergy spectrum of the system Hamiltonian, we can discriminate TIT and double TIT from AT doublet and triplet, respectively. For the resonant case, the presence of the TIT does not exhibit distinguishable anticrossing in the eigenenergy spectrum in the weak-tunneling regime, while the occurrence of double anticrossings in the strong-tunneling regime shows that the TIT evolves to the AT doublet...
February 15, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29442012/effects-of-the-oligostilbenes-from-iris-lactea-pall-var-chinensis-fisch-koidz-on-the-adipocytes-differentiation-of-3t3-l1-cells
#2
Fan-Fang Tie, Guang-Xiang Luan, Wen-Na Zhou, Zhen-Hua Wang, Xiao-Bing Shi, Gang Li, Hong-Lun Wang
The dried seeds of Iris lactea Pall. var. chinensis (Fisch.) Koidz, an important traditional Chinese medicine, are regarded to have effects of clearing heat, eliminating dampness and pharyngitis and so on. It has been used in the treatment of jaundice, diarrhea, leucorrhea and carbuncles. Previous phytochemical studies of Iris species showed the presence of flavones, isoflavones, triterpenes and stilbenes. In our previous research, we isolated five known oligostilbenes, vitisin A, vitisin B, vitisin C, vitisin D, and cis-vitisin A were successfully isolated from Iris lactea for the first time...
February 1, 2018: Die Pharmazie
https://www.readbyqxmd.com/read/29435112/lncrna-malat1-regulates-smooth-muscle-cell-phenotype-switch-via-activation-of-autophagy
#3
Tie-Feng Song, Li-Wen Huang, Ying Yuan, Hui-Qin Wang, Hong-Peng He, Wen-Jian Ma, Li-Hong Huo, Hao Zhou, Nan Wang, Tong-Cun Zhang
Vascular smooth muscle cells (VSMCs), switching from a differentiated to a proliferative phenotype, contribute to various vascular diseases. However, the role of long noncoding RNA metastasis-associated lung adenocarcinoma transcript 1 MALAT1 in the phenotype switching of VSMCs remains unclear. Here, we report that the knockdown of MALAT1 promotes the transformation of smooth muscle cells from a proliferative phenotype to a differentiated phenotype. MALAT1 knockdown inhibited cellular proliferation and migration, leading to significant cell cycle arrest in the G2 phase...
January 12, 2018: Oncotarget
https://www.readbyqxmd.com/read/29426512/surface-imprinted-polymers-based-on-amino-hyperbranched-magnetic-nanoparticles-for-selective-extraction-and-detection-of-chlorogenic-acid-in-honeysuckle-tea
#4
Yayun Zhao, Yuhai Tang, Jun He, Yuan Xu, Ruixia Gao, Junjie Zhang, Tie Chong, Li Wang, Xiaoshuang Tang
Novel water-compatible magnetic molecularly imprinted polymers were developed. The magnetic core was firstly grafted by methyl acrylate and ethanediamine to increase the number of amino groups, which could immobilize more templates and form high-density recognition sites. Dopamine was adopted as functional monomer and crosslinker to retighten templates and prepare hydrophilic polymers. The characterization, adsorption capability, selectivity, and reusability were investigated in detail. The limit of detection and quantification of the method were 0...
May 1, 2018: Talanta
https://www.readbyqxmd.com/read/29420226/serial-circulating-tumour-dna-analysis-during-multimodality-treatment-of-locally-advanced-rectal-cancer-a-prospective-biomarker-study
#5
Jeanne Tie, Joshua D Cohen, Yuxuan Wang, Lu Li, Michael Christie, Koen Simons, Hany Elsaleh, Suzanne Kosmider, Rachel Wong, Desmond Yip, Margaret Lee, Ben Tran, David Rangiah, Matthew Burge, David Goldstein, Madhu Singh, Iain Skinner, Ian Faragher, Matthew Croxford, Carolyn Bampton, Andrew Haydon, Ian T Jones, Christos S Karapetis, Timothy Price, Mary J Schaefer, Jeanne Ptak, Lisa Dobbyn, Natallie Silliman, Isaac Kinde, Cristian Tomasetti, Nickolas Papadopoulos, Kenneth Kinzler, Bert Volgestein, Peter Gibbs
OBJECTIVE: For patients with locally advanced rectal cancer (LARC), adjuvant chemotherapy selection following surgery remains a major clinical dilemma. Here, we investigated the ability of circulating tumour DNA (ctDNA) to improve risk stratification in patients with LARC. DESIGN: We enrolled patients with LARC (T3/T4 and/or N+) planned for neoadjuvant chemoradiotherapy. Plasma samples were collected pretreatment, postchemoradiotherapy and 4-10 weeks after surgery...
February 2, 2018: Gut
https://www.readbyqxmd.com/read/29416511/genome-wide-identification-and-expression-analysis-of-the-kup-family-under-abiotic-stress-in-cassava-manihot-esculenta-crantz
#6
Wenjun Ou, Xiang Mao, Chao Huang, Weiwei Tie, Yan Yan, Zehong Ding, Chunlai Wu, Zhiqiang Xia, Wenquan Wang, Shiyi Zhou, Kaimian Li, Wei Hu
KT/HAK/KUP (KUP) family is responsible for potassium ion (K+) transport, which plays a vital role in the response of plants to abiotic stress by maintaining osmotic balance. However, our understanding of the functions of the KUP family in the drought-resistant crop cassava (Manihot esculenta Crantz) is limited. In the present study, 21 cassava KUP genes (MeKUPs) were identified and classified into four clusters based on phylogenetic relationships, conserved motifs, and gene structure analyses. Transcriptome analysis revealed the expression diversity of cassava KUPs in various tissues of three genotypes...
2018: Frontiers in Physiology
https://www.readbyqxmd.com/read/29407743/removal-characteristic-of-surfactants-in-typical-industrial-and-domestic-wastewater-treatment-plants-in-northeast-china
#7
Fu-Jie Zhu, Wan-Li Ma, Tie-Fu Xu, Yi Ding, Xue Zhao, Wen-Long Li, Li-Yan Liu, Wei-Wei Song, Yi-Fan Li, Zi-Feng Zhang
Surfactants are widely used in household and industrial products for cleaning and/or solubilization in our daily life. Therefore, they are finally discharged into wastewater treatment plants (WWTPs), which may be the major point pollution source for environment if they were not completely removed during wastewater treatment. In this study, two typical industrial and domestic WWTPs with different wastewater treatment technologies were considered for the topic. Totally, two types of surfactants were analyzed in 24 h influent and each processing unit effluent...
February 5, 2018: Ecotoxicology and Environmental Safety
https://www.readbyqxmd.com/read/29402834/endothelial-gpr124-exaggerates-the-pathogenesis-of-atherosclerosis-by-activating-inflammation
#8
Dong-Mei Gong, Yan-Li Zhang, Dan-Yang Chen, Ling-Juan Hong, Feng Han, Qi-Bing Liu, Jian-Jun Jiang, Ying-Mei Lu
BACKGROUND/AIMS: Endothelial cell dysfunction is the principal pathological process underlying atherosclerotic cardiovascular disease. G protein-coupled receptor 124 (GPR124), an orphan receptor in the adhesion GPCR subfamily, promotes angiogenesis in the brain. In the present study, we explored the role of endothelial GPR124 in the development and progression of atherosclerosis in adult mice. METHODS: Using tetracycline-inducible transgenic systems, we generated mice expressing GPR124 specifically under control of the Tie-2 promoter...
January 25, 2018: Cellular Physiology and Biochemistry
https://www.readbyqxmd.com/read/29401814/temporal-evolution-of-condensation-and-precipitation-induced-by-a-22-tw-laser
#9
Jingjing Ju, Haiyi Sun, Xingkai Hu, Yonghong Liu, Yaoxiang Liu, Jingwei Wang, Cheng Wang, Tie-Jun Wang, Xueliang Guo, Jiansheng Liu, See Leang Chin, Ruxin Li, Zhizhan Xu
Water condensation and precipitation induced by 22-TW 800-nm laser pulses at 1 Hz in an open cloud chamber were investigated in a time-resolved manner. Two parts of precipitation in two independent periods of time were observed directly following each laser shot. One part started around the filament zone at t < 500 μs and ended at t ≅ 1.5 ms after the arrival of the femtosecond laser pulse. The other following the laser-induced energetic air motion (turbulence), started at t ≅ 20 ms and ended at t ≅ 120 ms...
February 5, 2018: Optics Express
https://www.readbyqxmd.com/read/29400658/human-erythrocyte-lifespan-measured-by-levitt-s-co-breath-test-with-newly-developed-automatic-instrument
#10
Hou-De Zhang, YongJian Ma, Qi-Fa Liu, Tie-Zhen Ye, Fan-Yi Meng, Yi-Wen Zhou, Guo-Pan Yu, Jian-Ping Yang, Hua Jiang, Quan-Shi Wang, Gui-Ping Li, Yong-Qiang Ji, Guo-Liang Zhu, Li-Tao Du, Kun-Mei Ji
&#13; Existing standard techniques for erythrocyte (RBC) lifespan measurement, such as quantitation of labeling with isotopes or biotin, are cumbersome and time-consuming. Given that endogenous CO originates mainly from degraded RBCs, a team lead by Levitt developed a CO breath test to enable more efficient RBC lifespan estimation. The purpose of this study was to evaluate the reliability of Levitts CO breath test method with our newly developed automatic instrument. RBC lifespan measurements conducted by Levitt's CO breath test method were conducted in 109 healthy subjects and 91 patients with chronic hemolytic anemia...
February 5, 2018: Journal of Breath Research
https://www.readbyqxmd.com/read/29399153/silymarin-mediated-regulation-of-the-cell-cycle-and-dna-damage-response-exerts-antitumor-activity-in-human-hepatocellular-carcinoma
#11
Hong Cui, Tie-Ling Li, Hai-Feng Guo, Jia-Liang Wang, Ping Xue, Ying Zhang, Jing-Hui Fan, Zhi-Ping Li, Yue-Juan Gao
A novel module-search algorithm method was used to screen for potential signatures and investigate the molecular mechanisms of inhibiting hepatocellular carcinoma (HCC) growth following treatment with silymarin (SM). The modules algorithm was used to identify the modules via three major steps: i) Seed gene selection; ii) module search by seed expansion and entropy minimization; and iii) module refinement. The statistical significance of modules was computed to select the differential modules (DMs), followed by the identification of core modules using the attract method...
January 2018: Oncology Letters
https://www.readbyqxmd.com/read/29397818/-analysis-of-early-death-and-factors-affecting-prognosis-of-patients-with-acute-promyelocytic-leukemia
#12
Li-Wei Fang, Tie-Jun Qin, Ze-Feng Xu, Yue Zhang, Hong-Li Zhang, Li-Juan Pan, Nai-Bo Hu, Shi-Qiang Qu, Bing Li, Zhi-Jian Xiao
OBJECTIVE: To investigate the factors affecting the early-death, overall survival (OS) and relapse-free survival (RFS) of acute promyelocytic leukemia (APL) patients. METHODS: The clinical and laboratorial charachteristics of 176 APL patients in our center were analyzed retrospectively during January 2002 to Mar 2016. The risk factors of early death and factors affecting OS and RFS of patients were analyzed. RESULTS: Among total of 176 patients, early death occured in 10 patients...
February 2018: Zhongguo Shi Yan Xue Ye Xue za Zhi
https://www.readbyqxmd.com/read/29391274/association-of-rs2271037-and-rs3749585-polymorphisms-in-corin-with-susceptibility-to-hypertension-in-a-chinese-han-population-a-case-control-study
#13
Yan-Li Chen, Tie-Jun Li, Ying Hao, Bao-Gang Wu, Hong Li, Ning Geng, Zhao-Qing Sun, Li-Qiang Zheng, Ying-Xian Sun
Corins are membrane-bound protease that regulates blood pressure by activating the natriuretic peptides. These pro-atrial natriuretic peptide convertases are essential for sodium homeostasis and normal blood pressure. CORIN variants have been identified in humans and other animals, but no studies of CORIN polymorphisms have been conducted in northeastern China. This study aims to investigate the association of 2 single nucleotide polymorphisms (SNPs) in CORIN (rs2271037 and rs3749585) with hypertension, as well as their potential interaction with some risk factors of hypertension in a Han population of northeastern China...
January 29, 2018: Gene
https://www.readbyqxmd.com/read/29390440/myeloperoxidase-antineutrophil-cytoplasmic-antibody-anca-associated-systemic-vasculitis-developed-from-anca-negative-renal-limited-vasculitis-a-case-report
#14
Xiao-Li Li, Peng-Cheng Xu, Tong Chen, Tie-Kun Yan, Jian-Qing Jiang, Jun-Ya Jia, Li Wei, Wen-Ya Shang, Shui-Yi Hu
RATIONALE: The relationship between antineutrophil cytoplasmic autoantibody (ANCA)-associated vasculitis (AAV) and ANCA-negative vasculitis has not been elucidated. PATIENT CONCERNS: A 64-year-old female with edema and proteinuria was admitted. A kidney biopsy indicated focal proliferative nephritis with crescents in 25% of glomeruli. Serum ANCA was negative. Eighteen months later, systemic symptoms emerged and acute kidney injury occurred. Serum ANCA against myeloperoxidase (MPO) turned positive...
December 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29385272/what-does-the-world-think-of-ankyloglossia
#15
Ruilin R Jin, Alastair Sutcliffe, Maximo Vento, Claudelle Miles, Javeed Travadi, Kumar Kishore, Keiji Suzuki, David Todd, Susanne Wooderson, Azanna Ahmad Kamar, Li Ma, John Smyth, Ju Lee Oei
AIM: The diagnosis of tongue-tie (or ankyloglossia) has increased more than 10-fold in some countries. Whether this is a global phenomenon or related to cultural and professional differences is uncertain. METHODS: An online survey in English, Japanese, Mandarin Chinese and Spanish was disseminated between May to November 2016 via 27 international professional bodies to >30 clinical professions chosen a priori to represent occupations involved in the management of neonatal ankyloglossia...
January 31, 2018: Acta Paediatrica
https://www.readbyqxmd.com/read/29384844/modified-trapeziectomy-with-ligament-reconstruction-tendon-interposition-for-the-treatment-of-advanced-thumb-carpometacarpal-arthritis-a-case-report
#16
Ji Peng You, Lu Lu, Cong Jie Li, Bao Ren, Tao Wang
RATIONALE: Thumb carpometacarpal (CMC) arthritis is a common disease. Various procedures have been described for the treatment of advanced thumb CMC arthritis. This essay shows a CMC arthritis case treated by modified trapeziectomy with ligament reconstruction tendon interposition (LRTI). PATIENT CONCERNS: A 53-year-old Chinese female complained of pain and swelling at the base of the left thumb for 10 years. Visual analog scale (VAS) for thumb was 7 points, Disabilities of Arm, Shoulder and Hand (DASH) score was 51 points, and Kapandji score was 6 points before surgery...
February 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29384728/the-ambipolar-evolution-of-a-high-performance-wse2-transistor-assisted-by-a-ferroelectric-polymer
#17
Dan Li, Xudong Wang, Yan Chen, Sixin Zhu, Fan Gong, Guangjian Wu, Caimin Meng, Lan Liu, Lin Wang, Tie Lin, Shuo Sun, Hong Shen, Xingjun Wang, Weida Hu, Jianlu Wang, Jinglan Sun, Xiangjian Meng, Junhao Chu
In recent years, the electrical characteristics of WSe2 field-effect transistors (FETs) have been widely investigated with various dielectrics. Among them, being able to perfectly tune the polarity of WSe2 is meaningful and promising work. In this work, we systematically study the electrical properties of bilayer WSe2 FETs modulated by ferroelectric polymer poly(vinylidenefluoride-co-trifluoroethylene) (P(VDF-TrFE)). Compared to traditional gate dielectric SiO2, the P(VDF-TrFE) can not only tune both electron and hole concentrations to the same high level, but also improve the hole mobility of bilayer WSe2 to 265...
January 31, 2018: Nanotechnology
https://www.readbyqxmd.com/read/29384210/generation-of-hematopoietic-cells-from-mouse-pluripotent-stem-cells-in-a-3d-culture-system-of-self-assembling-peptide-hydrogel
#18
Wei Shan, Binsheng Wang, Yulin Xu, Xia Li, Xue Li, Huafang Wang, Yu Lin, Ruxiu Tie, Qianhao Zhao, Jinyong Wang, Weiyan Zheng, Yongxian Hu, Jimin Shi, Xiaohong Yu, He Huang
In vitro generation of HSCs from pluripotent stem cells (PSCs) can be regarded as novel therapeutic approaches for replacing bone marrow (BM) transplantation without immune rejection or graft versus host disease(GVHD). To date, many differentiation approaches have been evaluated in terms of directing PSCs toward different hematopoietic cell types, yet, low efficiency and no function restrict the further hematopoietic differentiation study, our research aim to develop a three dimention (3D) hematopoietic differentiation approach that serve as recapitulation of embryonic development in vitro to a degree of complexity not achievable in a two dimention (2D) culture system...
January 31, 2018: Journal of Cellular Physiology
https://www.readbyqxmd.com/read/29356917/identification-and-analysis-of-chek2-germline-mutations-in-chinese-brca1-2-negative-breast-cancer-patients
#19
Zhenhua Fan, Tao Ouyang, Jinfeng Li, Tianfeng Wang, Zhaoqing Fan, Tie Fan, Benyao Lin, Ye Xu, Yuntao Xie
PURPOSE: Cell-cycle-checkpoint kinase 2 (CHEK2) is an important moderate-penetrance breast cancer predisposition gene; however, recurrent CHEK2 mutations found in Caucasian women are very rare in Chinese population. We investigated the mutation spectrum and clinical relevance of CHEK2 germline mutations in Chinese breast cancer patients. METHODS: The entire coding regions and splicing sites of CHEK2 were screened in 7657 Chinese BRCA1/2-negative breast cancer patients, using 62-gene panel-based sequencing...
January 22, 2018: Breast Cancer Research and Treatment
https://www.readbyqxmd.com/read/29354962/-professor-wang-fuchun-s-experience-in-the-acupoint-selection-of-clinical-treatment-with-acupuncture-and-moxibustion
#20
Hailin Jiang, Chengyu Liu, Lijuan Ha, Tie Li
Professor WANG Fuchun's experience in the acupoint selection of clinical treatment with acupuncture and moxibustion was summarized. The main acupoints are selected by focusing on the chief symptoms of disease, the supplementary points are selected by differentiating the disorders. The acupoints are modified in terms of the changes of sickness. The effective acupoints are selected flexibly in accordance with the specific effects of points. The summary on the acupoint selection reflects professor WANG Fuchun's academic thoughts and clinical experience and effectively instructs the clinical practice of acupuncture and moxibustion...
November 12, 2017: Zhongguo Zhen Jiu, Chinese Acupuncture & Moxibustion
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