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Micronutrients and depression

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https://www.readbyqxmd.com/read/27890954/prevalence-of-vitamin-b12-and-folic-acid-deficiency-in-hiv-positive-patients-and-its-association-with-neuropsychiatric-symptoms-and-immunological-response
#1
Prabha M R Adhikari, Mukta N Chowta, John T Ramapuram, Satish Rao, Karthik Udupa, Sahana Devdas Acharya
BACKGROUND: Deficiency of micronutrients is prevalent even before the development of symptoms of HIV disease and is associated with accelerated HIV disease progression. AIMS: This study evaluates the prevalence of folate and Vitamin B12 deficiency in HIV-positive patients with or without tuberculosis (TB) and its association with neuropsychiatric symptoms and immunological response. SETTINGS AND DESIGN: Cross-sectional, observational study in an outpatient setting...
July 2016: Indian Journal of Sexually Transmitted Diseases
https://www.readbyqxmd.com/read/27872866/roles-of-zinc-signaling-in-the-immune-system
#2
REVIEW
Shintaro Hojyo, Toshiyuki Fukada
Zinc (Zn) is an essential micronutrient for basic cell activities such as cell growth, differentiation, and survival. Zn deficiency depresses both innate and adaptive immune responses. However, the precise physiological mechanisms of the Zn-mediated regulation of the immune system have been largely unclear. Zn homeostasis is tightly controlled by the coordinated activity of Zn transporters and metallothioneins, which regulate the transport, distribution, and storage of Zn. There is growing evidence that Zn behaves like a signaling molecule, facilitating the transduction of a variety of signaling cascades in response to extracellular stimuli...
2016: Journal of Immunology Research
https://www.readbyqxmd.com/read/27792245/malnutrition-and-risk-of-structural-brain-changes-seen-on-magnetic-resonance-imaging-in-older-adults
#3
Marian A E de van der Schueren, Sabine Lonterman-Monasch, Wiesje M van der Flier, Mark H Kramer, Andrea B Maier, Majon Muller
OBJECTIVES: To study the associations between protein energy malnutrition, micronutrient malnutrition, brain atrophy, and cerebrovascular lesions. DESIGN: Cross-sectional. SETTING: Geriatric outpatient clinic. PARTICIPANTS: Older adults (N = 475; mean age 80 ± 7). MEASUREMENTS: Nutritional status was assessed using the Mini Nutritional Assessment (MNA) and according to serum micronutrient levels (vitamins B1, B6, B12, D; folic acid)...
October 28, 2016: Journal of the American Geriatrics Society
https://www.readbyqxmd.com/read/27617497/you-are-what-you-eat-the-impact-of-nutrition-on-alcohol-and-drug-use
#4
Ryan D Schroeder, George E Higgins
BACKGROUND: Experimental research has shown that nutrition influences behavioral deviance. OBJECTIVES: The current project addresses the impact of nutrition on problem alcohol and drug use in a nationally representative sample of US adults. METHODS: The study relies on the daily dietary nutrition data and the substance use measures in the 2007-2008 National Health and Nutrition Examination Survey. RESULTS: The findings generally show that macronutrients increase the odds of substance use and micronutrients decrease the odds of substance use, especially among females...
September 12, 2016: Substance Use & Misuse
https://www.readbyqxmd.com/read/27365952/effect-of-vitamin-b12-and-folic-acid-supplementation-on-neuropsychiatric-symptoms-and-immune-response-in-hiv-positive-patients
#5
Prabha M Adhikari, Mukta N Chowta, John T Ramapuram, Satish B Rao, Karthik Udupa, Sahana D Acharya
BACKGROUND: Micronutrients such as B12 and folic acid deficiencies are found in higher number in HIV-infected patients. OBJECTIVE: We conducted a study to examine the effect of Vitamin B12 and folic acid supplementation on neuropsychiatric manifestations, CD4 count, and anthropometric measurements in HIV-positive patients. MATERIALS AND METHODS: Three different groups of HIV patients, namely, HIV patients with tuberculosis, HIV patients with neuropsychiatric manifestations, and asymptomatic HIV patients with 50 patients in each group were included in the study...
July 2016: Journal of Neurosciences in Rural Practice
https://www.readbyqxmd.com/read/27355911/nutritional-supplements-for-people-being-treated-for-active-tuberculosis
#6
REVIEW
Liesl Grobler, Sukrti Nagpal, Thambu D Sudarsanam, David Sinclair
BACKGROUND: Tuberculosis and malnutrition are linked in a complex relationship. Tuberculosis may cause undernutrition through increased metabolic demands and decreased intake, and nutritional deficiencies may worsen the disease, or delay recovery by depressing important immune functions. At present, there is no evidence-based nutritional guidance for adults and children being treated for tuberculosis. OBJECTIVES: To assess the effects of oral nutritional supplements in people being treated with antituberculous drug therapy for active tuberculosis...
2016: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/27097046/nut-consumption-is-associated-with-depressive-symptoms-among-chinese-adults
#7
Qian Su, Bin Yu, Haiyan He, Qing Zhang, Ge Meng, Hongmei Wu, Huanmin Du, Li Liu, Hongbin Shi, Yang Xia, Xiaoyan Guo, Xing Liu, Chunlei Li, Xue Bao, Yeqing Gu, Liyun Fang, Fei Yu, Huijun Yang, Shaomei Sun, Xing Wang, Ming Zhou, Qiyu Jia, Honglin Zhao, Kun Song, Kaijun Niu
BACKGROUND: Affective disorders, especially depressive symptoms, bring such a burden to mortality and morbidity that they are associated with physical and psychological health and quality of life. Nuts, a foodstuff rich in multiple micronutrients, macronutrients, and other useful components, were considered to be a protector against depressive symptoms. Here, we conducted an analysis to examine the relationship between nut consumption and depressive symptoms. METHODS: The study performed a cross-sectional study to examine whether nut consumption is related to depressive symptoms among 13,626 inhabitants in Tianjin...
April 20, 2016: Depression and Anxiety
https://www.readbyqxmd.com/read/27060705/the-impact-of-maternal-diet-fortification-with-lipid-based-nutrient-supplements-on-postpartum-depression-in-rural-malawi-a-randomised-controlled-trial
#8
Robert C Stewart, Per Ashorn, Eric Umar, Kathryn G Dewey, Ulla Ashorn, Francis Creed, Atif Rahman, Barbara Tomenson, Elizabeth L Prado, Ken Maleta
Perinatal depression is highly prevalent in low-and-middle-income countries and has been linked to poor child health. Suboptimal maternal nutrition may be a risk factor for perinatal depression. In this randomised-controlled trial conducted in rural Malawi, we set out to test the hypothesis that women taking a fatty acid-rich lipid-based nutrient supplement (LNS) would have fewer depressive symptoms postpartum than those taking iron-folate (IFA) or multiple-micronutrient (MMN) capsules. Women were recruited from antenatal clinics and randomised to receive LNS or MMN during pregnancy and for 6 months postpartum, or IFA during pregnancy only...
April 5, 2016: Maternal & Child Nutrition
https://www.readbyqxmd.com/read/27035272/correlation-of-clinical-response-with-homocysteine-reduction-during-therapy-with-reduced-b-vitamins-in-patients-with-mdd-who-are-positive-for-mthfr-c677t-or-a1298c-polymorphism-a-randomized-double-blind-placebo-controlled-study
#9
Arnold W Mech, Andrew Farah
OBJECTIVE: This study was designed to evaluate the efficacy and safety of reduced B vitamins as monotherapy in adults with major depressive disorder (MDD) who were also positive for at least 1 methylenetetrahydrofolate reductase (MTHFR) polymorphism associated with depression and further test the hypothesis that reduced (metabolized) B vitamins will lower homocysteine in a majority of clinically responding patients. METHODS: 330 adult patients with MDD (DSM-5) and positive for either MTHFR C677T or A1298C polymorphism were enrolled in a trial conducted between August 1, 2014, and April 3, 2015...
May 2016: Journal of Clinical Psychiatry
https://www.readbyqxmd.com/read/26968915/promising-link-between-selenium-and-peroxisome-proliferator-activated-receptor-gamma-in-the-treatment-protocols-of-obesity-as-well-as-depression
#10
M M Donma, O Donma
Considerable interest has been given to the significance of peroxisome proliferator activated receptors (PPARs) in macronutrient metabolism, however, there is not sufficient data concerning the interactions between PPARs and micronutrients. Investigations performed on PPARγ and one of the essential micronutrients selenium (Se) have shown that both parameters may lead to alterations in obesity-related or mood disorders. Therefore, it is plausible to consider PPARγ and Se together as a powerful combination during the treatment of two associated diseases; obesity and depression...
April 2016: Medical Hypotheses
https://www.readbyqxmd.com/read/26677763/telomerase-activity-and-its-association-with-psychological-stress-mental-disorders-lifestyle-factors-and-interventions-a-systematic-review
#11
REVIEW
W Deng, S T Cheung, S W Tsao, X M Wang, A F Y Tiwari
OBJECTIVE: To summarise and discuss the association between telomerase activity and psychological stress, mental disorders and lifestyle factors. METHOD: A systematic review was carried out to identify prospective or retrospective studies and interventions published up to June 2015 that reported associations between telomerase activity and psychological stress, mental disorders and lifestyle factors. Electronic data bases of PubMed, ProQuest, CINAHL and Google Scholar were searched...
February 2016: Psychoneuroendocrinology
https://www.readbyqxmd.com/read/26634839/immunological-aspects-of-sport-nutrition
#12
REVIEW
Michael Gleeson
Prolonged bouts of exercise and heavy training regimens are associated with depression of immune system functions that can increase the risk of picking up opportunistic infections such as the common cold and influenza. Some common sport nutrition practices including high-carbohydrate diets and carbohydrate ingestion during exercise, training with low-glycogen stores, intentional dieting for weight loss, ingestion of high-dose antioxidant supplements and protein ingestion post exercise may influence immune system status in athletes...
February 2016: Immunology and Cell Biology
https://www.readbyqxmd.com/read/26613119/natural-products-micronutrients-and-nutraceuticals-for-the-treatment-of-depression-a-short-review
#13
Seyed Mohammad Nabavi, Maria Daglia, Nady Braidy, Seyed Fazel Nabavi
Objectives Depression is one of the most common psychiatric disorders, and the fourth leading cause of long-term disability throughout the world. Despite the availability of different classes of antidepressant drugs, most of them are not completely effective and above all are associated with many serious adverse effects. Recently, accumulating evidence suggests that dietary supplements rich in important phytochemicals possess beneficial therapeutic roles in depression. Methods In this review, we will first consider what is known about the pathogenesis of depression and discuss the need for more safe and efficacious treatment...
November 27, 2015: Nutritional Neuroscience
https://www.readbyqxmd.com/read/26482691/nutritional-guidance-improves-nutrient-intake-and-quality-of-life-and-may-prevent-falls-in-aged-persons-with-alzheimer-disease-living-with-a-spouse-nuad-trial
#14
RANDOMIZED CONTROLLED TRIAL
M H Suominen, T M Puranen, S K Jyväkorpi, U Eloniemi-Sulkava, H Kautiainen, U Siljamäki-Ojansuu, K H Pitkalä
OBJECTIVE: The aim was to examine the effect of tailored nutritional guidance on nutrition, health-related quality of life (HRQoL) and falls in persons with Alzheimer disease (AD). DESIGN: Randomised controlled trial. SETTING AND PARTICIPANTS: Persons with AD living with a spouse. INTERVENTION: Tailored nutritional guidance with home visits during one year. The control group received a written guide about nutrition in older adults and all community-provided normal care...
November 2015: Journal of Nutrition, Health & Aging
https://www.readbyqxmd.com/read/26283708/use-of-optimization-modeling-for-selecting-national-micronutrient-intervention-strategies-an-example-based-on-potential-programs-for-control-of-vitamin-a-deficiency-in-cameroon
#15
Kenneth H Brown, Reina Engle-Stone, Justin Kagin, Erica Rettig, Stephen A Vosti
Vitamin and mineral (micronutrient [MN]) deficiencies are common in lower income countries, especially among young children and women of reproductive age. These deficiencies are cause for serious concern because of their high prevalence and their associated complications, which include depressed immune function and increased risk and severity of infections, impaired neurocognitive development, and anemia, which together result in elevated mortality and reduced human productive capacity. A broad range of different intervention strategies are available to control MN deficiencies...
September 2015: Food and Nutrition Bulletin
https://www.readbyqxmd.com/read/26246320/a-healthy-dietary-pattern-at-midlife-combined-with-a-regulated-energy-intake-is-related-to-increased-odds-for-healthy-aging
#16
Karen E Assmann, Camille Lassale, Valentina A Andreeva, Claude Jeandel, Serge Hercberg, Pilar Galan, Emmanuelle Kesse-Guyot
BACKGROUND: Few studies have investigated the long-term impact of overall dietary patterns (DPs) on healthy aging (HA), and current findings are inconsistent. OBJECTIVE: Our study's objective was to investigate the association between empirically derived DPs in midlife and HA after 13 y of follow-up. METHODS: Baseline dietary data from repeated 24-h dietary records (on average, 10 records per participant) of a subsample of the SU.VI.MAX (SUpplémentation en Vitamines et Minéraux AntioXydants) study allowed extraction of 2 DPs with the use of principal components analysis on 37 food groups...
September 2015: Journal of Nutrition
https://www.readbyqxmd.com/read/26154816/a-randomised-trial-of-nutrient-supplements-to-minimise-psychological-stress-after-a-natural-disaster
#17
RANDOMIZED CONTROLLED TRIAL
Bonnie J Kaplan, Julia J Rucklidge, Amy R Romijn, Michael Dolph
After devastating flooding in southern Alberta in June 2013, we attempted to replicate a New Zealand randomised trial that showed that micronutrient (minerals, vitamins) consumption after the earthquakes of 2010-11 resulted in improved mental health. Residents of southern Alberta were invited to participate in a study on the potential benefit of nutrient supplements following a natural disaster. Fifty-six adults aged 23-66 were randomised to receive a single nutrient (vitamin D, n=17), a few-nutrients formula (B-Complex, n=21), or a broad-spectrum mineral/vitamin formula (BSMV, n=18)...
August 30, 2015: Psychiatry Research
https://www.readbyqxmd.com/read/26078821/markers-of-oxidative-stress-and-neuroprogression-in-depression-disorder
#18
REVIEW
Magdaléna Vaváková, Zdeňka Ďuračková, Jana Trebatická
Major depression is multifactorial disorder with high prevalence and alarming prognostic in the nearest 15 years. Several mechanisms of depression are known. Neurotransmitters imbalance and imbalance between neuroprogressive and neuroprotective factors are observed in major depression. Depression is accompanied by inflammatory responses of the organism and consequent elevation of proinflammatory cytokines and increased lipid peroxidation are described in literature. Neuropsychiatric disorders including major depression are also associated with telomerase shortening, oxidative changes in nucleotides, and polymorphisms in several genes connected to metabolism of reactive oxygen species...
2015: Oxidative Medicine and Cellular Longevity
https://www.readbyqxmd.com/read/25884227/essential-amino-acids-in-the-gluten-free-diet-and-serum-in-relation-to-depression-in-patients-with-celiac-disease
#19
Nathalie J M van Hees, Erik J Giltay, Susanne M A J Tielemans, Johanna M Geleijnse, Thomas Puvill, Nadine Janssen, Willem van der Does
INTRODUCTION: Celiac disease (CD) is associated with an increased risk of major depressive disorder, possibly due to deficiencies in micronutrients in the gluten-free diet. We aimed to investigate whether essential amino acids (i.e., the precursors of serotonin, dopamine and other neurotransmitters) are depleted in the diet and serum of CD patients with major depressive disorder. METHODS: In a cross-sectional study we assessed dietary intake of amino acids and serum levels of amino acids, in 77 CD patients on a gluten-free diet and in 33 healthy controls...
2015: PloS One
https://www.readbyqxmd.com/read/25869369/parenting-skills-and-emotional-availability-an-rct
#20
RANDOMIZED CONTROLLED TRIAL
Aisha K Yousafzai, Muneera A Rasheed, Arjumand Rizvi, Robert Armstrong, Zulfiqar A Bhutta
OBJECTIVE: To investigate whether a responsive stimulation intervention delivered to caregivers of young children either alone or integrated with nutrition interventions would benefit parenting skills and emotional availability to promote children's development and growth compared with either a nutrition intervention alone or the usual standard of care. METHODS: A cluster randomized factorial effectiveness trial was implemented in an impoverished community in Pakistan...
May 2015: Pediatrics
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