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Implant passivity

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https://www.readbyqxmd.com/read/28727998/enrichment-of-endogenous-fractalkine-and-anti-inflammatory-cells-via-aptamer-functionalized-hydrogels
#1
Syed Faaiz Enam, Jack R Krieger, Tarun Saxena, Brian E Watts, Claire E Olingy, Edward A Botchwey, Ravi V Bellamkonda
Early recruitment of non-classical monocytes and their macrophage derivatives is associated with augmented tissue repair and improved integration of biomaterial constructs. A promising therapeutic approach to recruit these subpopulations is by elevating local concentrations of chemoattractants such as fractalkine (FKN, CX3CL1). However, delivering recombinant or purified proteins is not ideal due to their short half-lives, suboptimal efficacy, immunogenic potential, batch variabilities, and cost. Here we report an approach to enrich endogenous FKN, obviating the need for delivery of exogenous proteins...
July 10, 2017: Biomaterials
https://www.readbyqxmd.com/read/28727156/safety-and-effectiveness-of-a-6-french-mri-conditional-pacemaker-lead-the-ingevitytm-clinical-investigation-study-results
#2
Jens C Nielsen, Michael Giudici, Jose Maria Tolasana Viu, Engwooi Chew, Elke Sommerijns, Nicholas Wold, Linda Evert, Charles J Love, Kenneth Stein, Hedrich Olaf
BACKGROUND: The design of pacemaker leads has continued to evolve; ease of lead handling, improved electrical performance and MRI conditional aspects have become more important, while safety remains critical. The INGEVITY™ family leads was designed to provide MRI conditional aspects, decreased diameter, and improved performance of pacemaker leads. The INGEVITY study is an investigational device exemption trial evaluating the acute and chronic safety and effectiveness of these leads...
July 20, 2017: Pacing and Clinical Electrophysiology: PACE
https://www.readbyqxmd.com/read/28720339/in%C3%A2-vitro-fit-of-cad-cam-complete-arch-screw-retained-titanium-and-zirconia-implant-prostheses-fabricated-on-4-implants
#3
Hadi Al-Meraikhi, Burak Yilmaz, Edwin McGlumphy, William Brantley, William M Johnston
STATEMENT OF PROBLEM: Computer-aided designed and computer-aided manufactured (CAD-CAM) titanium and zirconia implant-supported fixed implant prostheses on 4 implants have become popular. The precision and accuracy of their interface fit has not been widely researched. PURPOSE: The purpose of this in vitro study was to compare the marginal fit of zirconia and titanium implant-supported screw-retained CAD-CAM complete fixed dental prostheses (CFDP) fit with a standardized cast simulating the all-on-4 implant distribution...
July 15, 2017: Journal of Prosthetic Dentistry
https://www.readbyqxmd.com/read/28719860/liposome-modified-titanium-surface-a-strategy-to-locally-deliver-bioactive-molecules
#4
Vincenzo De Leo, Monica Mattioli-Belmonte, Maria Teresa Cimmarusti, Annamaria Panniello, Manuela Dicarlo, Francesco Milano, Angela Agostiano, Elvira De Giglio, Lucia Catucci
Titanium and its alloys are widely employed materials for implants in orthopedic or dental surgery due to their mechanical properties, resistance to corrosion and osseointegration capability. However adverse reactions at the tissue/implant interface may occur, which limit the success of the osseointegration process. Therefore, different strategies have to be used to overcome these drawbacks. In this work, we developed two different liposome-based coatings on titanium surfaces as drug or bioactive molecule deposits for dental/orthopedic implant applications...
July 8, 2017: Colloids and Surfaces. B, Biointerfaces
https://www.readbyqxmd.com/read/28719403/passive-transcutaneous-bone-conduction-hearing-implants-a-systematic-review
#5
Timothy Cooper, Brendan McDonald, Allan Ho
OBJECTIVE: To systematically review the literature on currently available passive transcutaneous bone conduction hearing implants (pTCBI) with regard to complications, audiological outcomes, and quality-of-life scores. DATA SOURCES: MEDLINE, EMBASE, Scopus, and Cochrane Library. STUDY SELECTION: All identified English-language articles reporting on the implantation of currently available pTCBI's and their complications. Both pediatric and adult patients were included...
July 17, 2017: Otology & Neurotology
https://www.readbyqxmd.com/read/28717576/demodulation-of-quasi-quadrature-interferometric-signals-for-use-in-the-totally-implantable-hearing-aids
#6
Milos C Tomic, Zoran V Djinovic, Slobodan J Petricevic
We propose and experimentally prove an algorithm for demodulation of interferometric signals, modified for use in a totally implantable hearing aid device. A fiber optic configuration, which generates two quasi-quadrature signals by a passive 3x3 coupler, for a non-contact detection of the middle ear ossicle vibration is employed. We simulated the ossicle vibration and large movements and demonstrated the effectiveness of the algorithm to compensate changes of the signal DC values and the phase shift introduced by the coupler...
July 1, 2017: Biomedical Optics Express
https://www.readbyqxmd.com/read/28711374/the-components-of-shoulder-and-elbow-movements-as-goals-of-primary-reconstructive-operation-in-obstetric-brachial-plexus-lesions
#7
Jerzy Luszawski, Wiesław Marcol, Marek Mandera
Most of the cases of obstetric brachial plexus lesions (OBPL) show satisfactory improvement with conservative management, but in about 25% some surgical treatment is indicated. The present paper analyzes the effects of primary reconstructive surgeries in aspect of achieving delineated intraoperatively goals. Children operated before the age of 18 months with follow-up period longer than 1 year were selected. Therapeutic goals established during the operation were identified by analysis of initial clinical status and operative protocols...
June 30, 2017: Neurologia i Neurochirurgia Polska
https://www.readbyqxmd.com/read/28711060/native-point-defects-on-hydrogen-passivated-4h-sic-0001-surface-and-the-effects-on-metal-adsorptions
#8
Tingting Wang, Guiwu Liu, Yuanyuan Li, Haigang Hou, Ziwei Xu, Mingsong Wang, Guanjun Qiao
With the continued expansion of silicon carbide's (SiC) applications, atomistic understanding on the native point defects of its surfaces, particularly on those of the hydrogen-passivated (HP) 4H-SiC (0001) surface, becomes imperative. Using first-principles calculations, the structures and formation energies of several typical native point defects (e.g., ISi, IC, VSi, VC, and SiC) on the (0001) HP-surface of 4H-SiC were systematically explored, including the effects of the unit cell size, environmental condition, charge state, and hydrogen incorporation...
July 14, 2017: Journal of Chemical Physics
https://www.readbyqxmd.com/read/28709673/stereophotogrammetric-impression-making-for-polyoxymethylene-milled-immediate-partial-fixed-dental-prostheses
#9
Miguel Gómez-Polo, Cristina Gómez-Polo, Jaime Del Río, Rocío Ortega
Immediate post-extraction and same-day placement of interim prostheses have increased patient acceptance of implant-supported prostheses. However, for immediate prostheses supported by multiple implants, meeting passive fit and esthetic standards is often challenging. In this clinical report, implant photogrammetry was combined with conventionally obtained digitized casts to prepare an interim, milled prosthesis from a polyoxymethylene (POM) disk, using computer-aided design and computer-aided manufacturing techniques...
July 11, 2017: Journal of Prosthetic Dentistry
https://www.readbyqxmd.com/read/28678378/successful-treatment-of-passive-fecal-incontinence-in-an-animal-model-using-engineered-biosphincters-a-3-month-follow-up-study
#10
Jaime L Bohl, Elie Zakhem, Khalil N Bitar
Fecal incontinence (FI) is the involuntary passage of fecal material. Current treatments have limited successful outcomes. The objective of this study was to develop a large animal model of passive FI and to demonstrate sustained restoration of fecal continence using anorectal manometry in this model after implantation of engineered autologous internal anal sphincter (IAS) biosphincters. Twenty female rabbits were used in this study. The animals were divided into three groups: (a) Non-treated group: Rabbits underwent IAS injury by hemi-sphincterectomy without treatment...
July 5, 2017: Stem Cells Translational Medicine
https://www.readbyqxmd.com/read/28675194/aortic-stenosis-pathogenesis-prediction-of-progression-and-percutaneous-intervention
#11
D Natarajan, B Prendergast
Aortic stenosis is common and an important cause of morbidity and mortality. Prevalence will increase significantly in forthcoming decades as a function of the ageing population; treatment by means of surgery or percutaneous intervention is expensive. Epidemiological, mechanistic and interventional studies are therefore vital to determine optimal and innovative treatments and their funding. Recent studies suggest that aortic stenosis is not a passive degenerative disease, but an active process involving several pathways, including lipid infiltration, chronic inflammation, fibrosis formation, osteoblast activation, and active valve mineralisation...
June 2017: Journal of the Royal College of Physicians of Edinburgh
https://www.readbyqxmd.com/read/28655695/influences-of-prophylactic-implantation-iabp-and-passive-emergency-placement-iabp-in-clinical-prognosis-of-high-risk-of-coronary-bypass-patients
#12
Ying Zhang
This paper aims to study the influences of prophylactic placement of intra-aortic balloon pump (IABP) and passive emergency placement of IABP on the prognosis of patients with high risk of coronary bypass. In this study, 70 patients with high-risk coronary artery bypass IABP admitted to our hospital from August 2012 to August 2015 were selected and retrospectively analyzed. These patients were divided into two groups based on the timing of IABP placement, namely prophylactic placement of IABP group (group A, n=35) and passive emergency placement of IABP group (group B, n=35)...
May 2017: Pakistan Journal of Pharmaceutical Sciences
https://www.readbyqxmd.com/read/28649282/asymmetric-dna-methylation-of-cpg-dyads-is-a-feature-of-secondary-dmrs-associated-with-the-dlk1-gtl2-imprinting-cluster-in-mouse
#13
Megan Guntrum, Ekaterina Vlasova, Tamara L Davis
BACKGROUND: Differential DNA methylation plays a critical role in the regulation of imprinted genes. The differentially methylated state of the imprinting control region is inherited via the gametes at fertilization, and is stably maintained in somatic cells throughout development, influencing the expression of genes across the imprinting cluster. In contrast, DNA methylation patterns are more labile at secondary differentially methylated regions which are established at imprinted loci during post-implantation development...
2017: Epigenetics & Chromatin
https://www.readbyqxmd.com/read/28649147/multiblock-high-order-large-eddy-simulation-of-powered-fontan-hemodynamics-towards-computational-surgery
#14
Yann T Delorme, Mark D Rodefeld, Steven H Frankel
Children born with only one functional ventricle must typically undergo a series of three surgeries to obtain the so-called Fontan circulation in which the blood coming from the body passively flows from the Vena Cavae (VCs) to the Pulmonary Arteries (PAs) through the Total Cavopulmonary Connection (TCPC). The circulation is inherently inefficient due to the lack of a subpulmonary ventricle. Survivors face the risk of circulatory sequelae and eventual failure for the duration of their lives. Current efforts are focused on improving the outcomes of Fontan palliation, either passively by optimizing the TCPC, or actively by using mechanical support...
January 17, 2017: Computers & Fluids
https://www.readbyqxmd.com/read/28638348/the-redox-balance-in-erythrocytes-plasma-and-periosteum-of-patients-with-titanium-fixation-of-the-jaw
#15
Jan Borys, Mateusz Maciejczyk, Adam J Krȩtowski, Bozena Antonowicz, Wioletta Ratajczak-Wrona, Ewa Jabłońska, Piotr Załęski, Danuta Waszkiel, Jerzy R Ładny, Piotr Żukowski, Anna Zalewska
Titanium miniplates and screws are commonly used for fixation of jaw fractured or osteotomies. Despite the opinion of their biocompatibility, in clinical practice symptoms of chronic inflammation around the fixation develop in some patients, even many years after the application of miniplates and screws. The cause of these complications is still an unanswered question. Taking into account that oxidative stress is one of the toxic action of titanium, we have evaluated the antioxidant barrier as well as oxidative stress in the erythrocytes, plasma and periosteum covering the titanium fixation of the jaw...
2017: Frontiers in Physiology
https://www.readbyqxmd.com/read/28625664/effects-of-different-numbers-of-mini-dental-implants-on-alveolar-ridge-strain-distribution-under-mandibular-implant-retained-overdentures
#16
Pongsakorn Warin, Pimduen Rungsiyakull, Chaiy Rungsiyakull, Pathawee Khongkhunthian
PURPOSE: To investigate the strains around mini-dental implants (MDIs) and retromolar edentulous areas when using different numbers of MDIs in order to retain mandibular overdentures. MATERIALS AND METHODS: Four different prosthetic situations were fabricated on an edentulous mandibular model including a complete denture (CD), and three overdentures, retained by four, three or two MDIs in the interforaminal region with retentive attachments. A static load of 200N was applied on the posterior teeth of the dentures under bilateral or unilateral loading conditions...
June 15, 2017: Journal of Prosthodontic Research
https://www.readbyqxmd.com/read/28624870/translatory-hip-kinematics-measured-with-optoelectronic-surgical-navigation
#17
Sima Zakani, John F Rudan, Randy E Ellis
PURPOSE: An optoelectronic surgical navigation system was used to detect small but measurable translational motion of human hip cadavers in high-range passive motions. Kinematic data were also examined to demonstrate the role of soft tissues in constraining hip translation. METHODS: Twelve cadaver hips were scanned using CT, instrumented for navigation, and passively taken through motion assessment. Center of the femoral head was tracked in the acetabular coordinates...
June 17, 2017: International Journal of Computer Assisted Radiology and Surgery
https://www.readbyqxmd.com/read/28618432/accuracy-of-digital-vs-conventional-implant-impression-approach-a-three-dimensional-comparative-in-vitro-analysis
#18
Kinga Basaki, Hasan Alkumru, Grace De Souza, Yoav Finer
PURPOSE: To assess the three-dimensional (3D) accuracy and clinical acceptability of implant definitive casts fabricated using a digital impression approach and to compare the results with those of a conventional impression method in a partially edentulous condition. MATERIALS AND METHODS: A mandibular reference model was fabricated with implants in the first premolar and molar positions to simulate a patient with bilateral posterior edentulism. Ten implant-level impressions per method were made using either an intraoral scanner with scanning abutments for the digital approach or an open-tray technique and polyvinylsiloxane material for the conventional approach...
July 2017: International Journal of Oral & Maxillofacial Implants
https://www.readbyqxmd.com/read/28616842/characterization-of-magneto-endosymbionts-as-mri-cell-labeling-and-tracking-agents
#19
Kimberly D Brewer, Ryan Spitler, Kayla R Lee, Andrea C Chan, Joyce C Barrozo, Abdul Wakeel, Chandler S Foote, Steven Machtaler, James Rioux, Juergen K Willmann, Papia Chakraborty, Bradley W Rice, Christopher H Contag, Caleb B Bell, Brian K Rutt
PURPOSE: Magneto-endosymbionts (MEs) show promise as living magnetic resonance imaging (MRI) contrast agents for in vivo cell tracking. Here we characterize the biomedical imaging properties of ME contrast agents, in vitro and in vivo. PROCEDURES: By adapting and engineering magnetotactic bacteria to the intracellular niche, we are creating magneto-endosymbionts (MEs) that offer advantages relative to passive iron-based contrast agents (superparamagnetic iron oxides, SPIOs) for cell tracking...
June 14, 2017: Molecular Imaging and Biology: MIB: the Official Publication of the Academy of Molecular Imaging
https://www.readbyqxmd.com/read/28609507/use-of-intraoral-welding-to-increase-the-predictability-of-immediately-loaded-computer-guided-implants
#20
Alberto Maria Albiero, Renato Benato, Andrea Benato, Marco Degidi
Inaccuracy of computer-guided implant placement may lead to complications when combined with an immediately loaded prefabricated prosthesis. The aim of this case series was to describe the use of an intraoral welding technique to increase the predictability of immediately loaded implants supporting a fixed full-arch prosthesis after computer-guided flapless implant placement. A total of 60 Ankylos plus implants (Dentsply) with a width of 3.5 mm and a length of 8 to 14 mm were placed consecutively in 10 patients...
July 2017: International Journal of Periodontics & Restorative Dentistry
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