Felipe Diego Toro-Hernández, Joaquín Migeot, Nicolás Marchant, Daniela Olivares, Franco Ferrante, Raúl González-Gómez, Cecilia González Campo, Sol Fittipaldi, Gonzalo M Rojas-Costa, Sebastian Moguilner, Andrea Slachevsky, Pedro Chaná Cuevas, Agustín Ibáñez, Sergio Chaigneau, Adolfo M García
Cognitive studies on Parkinson's disease (PD) reveal abnormal semantic processing. Most research, however, fails to indicate which conceptual properties are most affected and capture patients' neurocognitive profiles. Here, we asked persons with PD, healthy controls, and individuals with behavioral variant frontotemporal dementia (bvFTD, as a disease control group) to read concepts (e.g., 'sun') and list their features (e.g., hot). Responses were analyzed in terms of ten word properties (including concreteness, imageability, and semantic variability), used for group-level comparisons, subject-level classification, and brain-behavior correlations...
January 9, 2024: NPJ Parkinson's Disease