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https://www.readbyqxmd.com/read/28529541/differences-in-age-specific-hpv-prevalence-between-self-collected-and-health-personnel-collected-specimen-in-a-cross-sectional-study-in-ghana
#1
Adolf K Awua, Richard M K Adanu, Edwin K Wiredu, Edwin A Afari, Alberto Severini
BACKGROUND: HPV infections are ubiquitous and particularly common among sexually active young women. However, there are regional and national variations in age-specific HPV prevalence, which have implications for cervical cancer control. Data on age-specific HPV prevalences for Ghana and most sub-Saharan countries are scanty. Therefore, this study primarily sought to determine the age-specific HPV prevalence among women in a Ghanaian community and to determine whether these prevalences determined with health-personnel and self-collected specimens were comparable...
2017: Infectious Agents and Cancer
https://www.readbyqxmd.com/read/28527672/quality-of-life-among-long-term-survivors-of-advanced-stage-ovarian-cancer-a-cross-sectional-approach
#2
Susan K Lutgendorf, Eileen Shinn, Jeanne Carter, Susan Leighton, Keith Baggerly, Michele Guindani, Bryan Fellman, Marianne Matzo, George M Slavich, Marc T Goodman, William Tew, Jenny Lester, Kathleen M Moore, Beth Y Karlan, Douglas A Levine, Anil K Sood
PURPOSE: Long-term survival of women with advanced-stage ovarian cancer is relatively rare. Little is known about quality of life (QOL) and survivorship concerns of these women. Here, we describe QOL of women with advanced-stage ovarian cancer surviving for 8.5 years or longer and compare women with 0-1 recurrence to those with multiple recurrences. METHODS: Participants (n=56) recruited from 5 academic medical centers and the Ovarian Cancer Research Fund Alliance completed surveys regarding QOL (FACT-O), mood (CESD), social support (SPS), physical activity (IPAQ-SF), diet, and clinical characteristics...
May 17, 2017: Gynecologic Oncology
https://www.readbyqxmd.com/read/28509699/penis-transplantation-first-us-experience
#3
Curtis L Cetrulo, Kai Li, Harry M Salinas, Matthew D Treiser, Ilse Schol, Glen W Barrisford, Francis J McGovern, Adam S Feldman, Michael T Grant, Cigdem Tanrikut, Jeffrey H Lee, Richard J Ehrlichman, Paul W Holzer, Garry M Choy, Raymond W Liu, Zhi Yang Ng, Alexandre G Lellouch, Josef M Kurtz, William G Austen, Jonathan M Winograd, Branko Bojovic, Kyle R Eberlin, Ivy A Rosales, Robert B Colvin, Dicken S C Ko
OBJECTIVE: We describe the first successful penis transplant in the United States in a patient with a history of subtotal penectomy for penile cancer. BACKGROUND: Penis transplantation represents a new paradigm in restoring anatomic appearance, urine conduit, and sexual function after genitourinary tissue loss. To date, only 2 penis transplants have been performed worldwide. METHODS: After institutional review board approval, extensive medical, surgical, and radiological evaluations of the patient were performed...
May 15, 2017: Annals of Surgery
https://www.readbyqxmd.com/read/28502218/recommendations-to-reduce-inequalities-for-lgbt-people-facing-advanced-illness-accesscare-national-qualitative-interview-study
#4
Katherine Bristowe, Matthew Hodson, Bee Wee, Kathryn Almack, Katherine Johnson, Barbara A Daveson, Jonathan Koffman, Linda McEnhill, Richard Harding
BACKGROUND: Lesbian, gay, bisexual and/or trans (LGBT) people have higher risk of certain life-limiting illnesses and unmet needs in advanced illness and bereavement. ACCESSCare is the first national study to examine in depth the experiences of LGBT people facing advanced illness. AIM: To explore health-care experiences of LGBT people facing advanced illness to elicit views regarding sharing identity (sexual orientation/gender history), accessing services, discrimination/exclusion and best-practice examples...
April 1, 2017: Palliative Medicine
https://www.readbyqxmd.com/read/28493812/treatment-decision-regret-among-long-term-survivors-of-localized-prostate-cancer-results-from-the-prostate-cancer-outcomes-study
#5
Richard M Hoffman, Mary Lo, Jack A Clark, Peter C Albertsen, Michael J Barry, Michael Goodman, David F Penson, Janet L Stanford, Antoinette M Stroup, Ann S Hamilton
Purpose To determine the demographic, clinical, decision-making, and quality-of-life factors that are associated with treatment decision regret among long-term survivors of localized prostate cancer. Patients and Methods We evaluated men who were age ≤ 75 years when diagnosed with localized prostate cancer between October 1994 and October 1995 in one of six SEER tumor registries and who completed a 15-year follow-up survey. The survey obtained demographic, socioeconomic, and clinical data and measured treatment decision regret, informed decision making, general- and disease-specific quality of life, health worry, prostate-specific antigen (PSA) concern, and outlook on life...
May 11, 2017: Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology
https://www.readbyqxmd.com/read/28492995/general-health-status-of-long-term-cervical-cancer-survivors-after-radiotherapy
#6
Lee Sung Uk, Kim Young Ae, Yoon Young-Ho, Kim Yeon-Joo, Lim Myong Cheol, Park Sang-Yoon, Seo Sang-Soo, Park Ji Eun, Kim Joo-Young
PURPOSE: To evaluate the global health status of long-term cervical cancer survivors (LCCS) who survived for more than 4 years after curative radiation treatment (RT). PATIENTS AND METHODS: Medical records of 562 women treated with RT in our institution between 2003 and 2010 were reviewed. Excluding 259 women who died of disease or were lost to follow-up, disease status and late morbidities were evaluated in 303 LCCS. Quality of life (QoL) was analyzed in 168 LCCS using a questionnaire from the European Organization for the Research and Treatment of Cancer, and the results were compared with an age-matched healthy Korean female population...
May 10, 2017: Strahlentherapie und Onkologie: Organ der Deutschen Röntgengesellschaft ... [et Al]
https://www.readbyqxmd.com/read/28490338/international-evaluation-of-the-psychometrics-of-health-related-quality-of-life-questionnaires-for-use-among-long-term-survivors-of-testicular-and-prostate-cancer
#7
Marieke van Leeuwen, Jacobien M Kieffer, Fabio Efficace, Sophie D Fosså, Michel Bolla, Laurence Collette, Marc Colombel, Ugo De Giorgi, Bernhard Holzner, Lonneke V van de Poll-Franse, Hendrik van Poppel, Jeff White, Ronald de Wit, Susanne Osanto, Neil K Aaronson
BACKGROUND: Understanding of the physical, functional and psychosocial health problems and needs of cancer survivors requires cross-national and cross-cultural standardization of health-related quality of life (HRQoL) questionnaires that capture the full range of issues relevant to cancer survivors. To our knowledge, only one study has investigated in a comprehensive way whether a questionnaire used to evaluate HRQoL in cancer patients under active treatment is also reliable and valid when used among (long-term) cancer survivors...
May 11, 2017: Health and Quality of Life Outcomes
https://www.readbyqxmd.com/read/28488986/effect-of-a-smoking-cessation-program-on-sexual-function-recovery-following-robotic-prostatectomy-at-kaiser-permanente-southern-california
#8
Seena Safavy, Patrick S Kilday, Jeff M Slezak, George A Abdelsayed, Teresa N Harrison, Steven J Jacobsen, Gary W Chien
INTRODUCTION: The association between cigarette smoking and erectile dysfunction has been well established. Studies demonstrate improvements in erectile rigidity and tumescence as a result of smoking cessation. Radical prostatectomy is also associated with worsening of erectile function secondary to damage to the neurovascular bundles. To our knowledge, no previous studies have examined the relationship between smoking cessation after prostate cancer diagnosis and its effect on sexual function following robotic prostatectomy...
2017: Permanente Journal
https://www.readbyqxmd.com/read/28486701/cancer-in-transgender-people-evidence-and-methodological-considerations
#9
Hayley Braun, Rebecca Nash, Vin Tangpricha, Janice Brockman, Kevin Ward, Michael Goodman
Transgender people comprise a diverse group of individuals whose gender identity or expression differs from that originally assigned to them at birth. Some, but not all, transgender people elect to undergo medical gender affirmation, which may include therapy with cross-sex hormones and/or surgical change of the genitalia and other sex characteristics. As cross-sex hormones administered for the purposes of gender affirmation may be delivered at high doses and over a period of decades, the carcinogenicity of hormonal therapy in transgender people is an area of considerable concern...
January 1, 2017: Epidemiologic Reviews
https://www.readbyqxmd.com/read/28472698/colorectal-cancer-screening-and-adverse-childhood-experiences-which-adversities-matter
#10
Héctor E Alcalá, Jessica Keim-Malpass, Emma Mitchell
Adverse Childhood Experiences (ACEs) have been associated with an increased risk of a variety of diseases, including cancer. However, research has not paid enough attention to the association between ACEs and cancer screening. As such, the present study examined the association between ACEs and ever using colorectal cancer (CRC) screening, among adults age 50 and over. Analyses used the 2011 Behavioral Risk Factor Surveillance System (n=24,938) to model odds of ever engaging in CRC screening from nine different adversities...
May 1, 2017: Child Abuse & Neglect
https://www.readbyqxmd.com/read/28463150/external-beam-radiation-therapy-or-brachytherapy-with-or-without-short-course-neoadjuvant-androgen-deprivation-therapy-results-of-a-multicenter-prospective-study-of-quality-of-life
#11
Hiram A Gay, Martin G Sanda, Jingxia Liu, Ningying Wu, Daniel A Hamstra, John T Wei, Rodney L Dunn, Eric A Klein, Howard M Sandler, Christopher S Saigal, Mark S Litwin, Deborah A Kuban, Larry Hembroff, Meredith M Regan, Peter Chang, Jeff M Michalski
PURPOSE: The long-term effects of neoadjuvant androgen deprivation therapy (NADT) with radiation therapy on participant-reported health-related quality of life (HRQOL) have not been characterized in prospective multicenter studies. We evaluated HRQOL for 2 years among participants undergoing radiation therapy (RT) with or without NADT for newly diagnosed, early-stage prostate cancer. METHODS AND MATERIALS: We analyzed longitudinal cohort data from the Prostate Cancer Outcomes and Satisfaction with Treatment Quality Assessment Consortium to ascertain the HRQOL trajectory of men receiving NADT with external beam RT (EBRT) or brachytherapy...
June 1, 2017: International Journal of Radiation Oncology, Biology, Physics
https://www.readbyqxmd.com/read/28463105/prevalence-of-hpv-in-adults-aged-18-69-united-states-2011-2014
#12
Geraldine McQuillan, Deanna Kruszon-Moran, Lauri E Markowitz, Elizabeth R Unger, Ryne Paulose-Ram
Data from the National Health and Nutrition Examination Survey Human papillomavirus (HPV) is the most common sexually transmitted infection in the United States (1). Some HPV types can cause genital warts and are considered low risk, with a small chance for causing cancer. Other types are considered high risk, causing cancer in different areas of the body including the cervix and vagina in women, penis in men, and anus and oropharynx in both men and women (2). This report provides the most recent national estimates of oral HPV prevalence among adults aged 18-69 from the National Health and Nutrition Examination Survey (NHANES) 2011-2014, as well as prevalence of genital HPV among adults aged 18-59 from NHANES 2013-2014...
April 2017: NCHS Data Brief
https://www.readbyqxmd.com/read/28462944/functional-outcomes-of-clinically-high-risk-prostate-cancer-patients-treated-with-robot-assisted-radical-prostatectomy-a-multi-institutional-analysis
#13
F Abdollah, D Dalela, A Sood, J Sammon, R Cho, L Nocera, M Diaz, W Jeong, J O Peabody, N Fossati, G Gandaglia, A Briganti, F Montorsi, M Menon
BACKGROUND: To ascertain 3-year urinary continence (UC) and sexual function (SF) recovery following robot-assisted radical prostatectomy (RARP) for clinically high-risk prostate cancer (PCa). METHODS: Retrospective analyses of a prospectively maintained database for 769 patients with D'Amico high-risk PCa undergoing RARP at two tertiary care centers in the United States and Europe between 2001 and 2014. The association between time since RARP and recovery of UC (defined as 0 pad/one safety liner per day) and SF (defined as sexual health inventory for men (SHIM) score ⩾17) was tested in separate preoperative and post-operative Cox-proportional hazards regression models...
May 2, 2017: Prostate Cancer and Prostatic Diseases
https://www.readbyqxmd.com/read/28457651/prevalence-and-correlates-of-mental-health-problems-in-prostate-cancer-survivors-a-case-control-study-comparing-survivors-with-general-population-peers
#14
Marie-Anne van Stam, Henk G van der Poel, J L H Ruud Bosch, Corinne N Tillier, Simon Horenblas, Floor Mols, Neil K Aaronson
OBJECTIVE: The purpose of this study was to identify factors associated with mental health (MH) problems in prostate cancer (PC) survivors. Toward this end, we evaluated (1) differences in the prevalence of MH problems between PC survivors and age-matched men from the general population (GenPop) and (2) correlates of MH in PC survivors and the GenPop. METHODS AND MATERIALS: In this observational case-control study, we age-matched PC survivors (n = 644, alive≥5y after diagnosis of a stage I-IV carcinoma) recruited from Dutch community hospitals (Patient Reported Outcomes Following Initial treatment and Long-term Evaluation of Survivorship registry) with GenPop peers (n = 644) selected from a population-based sample recruited in general practices (NIVEL)...
April 27, 2017: Urologic Oncology
https://www.readbyqxmd.com/read/28456541/long-term-health-related-quality-of-life-outcomes-following-radical-cystectomy
#15
Paul T Gellhaus, Clint Cary, Hristos Z Kaimakliotis, Cynthia S Johnson, Michael Weiner, Michael O Koch, Richard Bihrle
OBJECTIVE: To evaluate the long-term (>5 years) health-related quality of life outcomes following radical cystectomy, comparing Indiana pouch (IP), neobladder (NB), and ileal conduit (IC). MATERIALS AND METHODS: The departmental radical cystectomy database was queried to identify patients who underwent radical cystectomy and urinary diversion for bladder cancer between 1991 and 2009 and had not died. Three hundred patients were identified and sent the validated Bladder Cancer Index (BCI) instrument...
April 26, 2017: Urology
https://www.readbyqxmd.com/read/28444552/income-and-health-related-quality-of-life-among-prostate-cancer-patients-over-a-one-year-period-after-radical-prostatectomy-a-linear-mixed-model-analysis
#16
Jens Klein, Daniel Lüdecke, Kerstin Hofreuter-Gätgens, Margit Fisch, Markus Graefen, Olaf von dem Knesebeck
PURPOSE: To examine income-related disparities in health-related quality of life (HRQOL) over a one-year period after surgery (radical prostatectomy) and its contributory factors in a longitudinal perspective. Evidence of associations between income and HRQOL among patients with prostate cancer (PCa) is sparse and their explanations still remain unclear. METHODS: 246 males of two German hospitals filled out a questionnaire at the time of acute treatment, 6 and 12 months later...
April 25, 2017: Quality of Life Research
https://www.readbyqxmd.com/read/28439055/-calcium-and-bone-metabolism-across-women-s-life-stages-bone-metabolism-and-estrogen-androgen-balance-in-women
#17
Toshiyuki Yasui, Miwa Fukuoka
Androgen as well as estrogen has physical, psychological and sexual roles in women. The action of androgen on bone health in women is important. The androgen receptor is expressed in osteoblasts and osteocytes but the mechanism has not been clarified in women. It has been reported that endogenous testosterone level was positively correlated with bone mineral density and higher testosterone level might be associated with decrease in bone fractures. Also, it has been reported that bone mineral density in women who received testosterone with estrogen was higher than that in women who received estrogen alone...
2017: Clinical Calcium
https://www.readbyqxmd.com/read/28438296/discussing-hpv-with-oropharyngeal-cancer-patients-a-cross-sectional-survey-of-attitudes-in-health-professionals
#18
Rachael H Dodd, Alice S Forster, Jo Waller, Laura A V Marlow
BACKGROUND: Human papillomavirus (HPV) is now known to cause a significant proportion of head and neck cancers (HNC). Qualitative research has shown that some health professionals find it difficult to discuss HPV with patients due to its sexually transmitted nature, and have concerns about their own knowledge of the virus. We used a survey to quantify attitudes towards discussing HPV among HNC health professionals. METHODS: We carried out a cross-sectional survey of HNC health professionals (n=260) in the UK and Ireland, assessing participants' knowledge of HPV, their experiences of and attitudes towards discussing HPV with patients, and their willingness to discuss HPV with their patients in the future...
May 2017: Oral Oncology
https://www.readbyqxmd.com/read/28437283/dilator-use-after-vaginal-brachytherapy-for-endometrial-cancer-a-randomized-feasibility-and-adherence-study
#19
Alexandra Hanlon, William Small, Jonathan Strauss, Lilie L Lin, Laura Hanisch, Liming Huang, Jinbing Bai, Jessica Wells, Deborah Watkins Bruner
BACKGROUND: Vaginal brachytherapy, a common treatment of endometrial cancer, is associated with high rates of vaginal stenosis. Recommendations for vaginal dilator use to minimize stenosis generally include 3 times per week for approximately 10 minutes per use. However, adherence rates range widely and are generally well less than 50%. OBJECTIVES: The aims of this study were to assess feasibility of recruitment to a study of dilator use and test a theoretically driven enhanced educational program (EEP) to increase adherence...
April 21, 2017: Cancer Nursing
https://www.readbyqxmd.com/read/28437239/tprevalence-of-hpv-in-adults-aged-18-69-united-states-2011-2014
#20
Geraldine McQuillan, Deanna Kruszon-Moran, Lauri E Markowitz, Elizabeth R Unger, Ryne Paulose-Ram
Data from the National Health and Nutrition Examination Survey ● During 2011-2014, prevalence of any oral human papillomavirus (HPV) for adults aged 18-69 was 7.3%; high-risk HPV was 4.0%. ● Overall, prevalence of any and high-risk oral HPV was lowest among non-Hispanic Asian adults; any oral HPV was highest among non-Hispanic black adults. ● Prevalence of any and high-risk oral HPV was higher in men than women except for high-risk HPV among Asian adults. ● During 2013-2014, prevalence of any and high-risk genital HPV for adults aged 18-59 was 45...
April 2017: NCHS Data Brief
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