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Breast cancer MRI, mass segmentation

Ravza Yilmaz, Ali Aslan Demir, Atilla Kaplan, Dilek Sahin, Enver Ozkurt, Memduh Dursun, Gulden Acunas
PURPOSE: To identify the magnetic resonance imaging (MRI) appearance of idiopathic granulomatous mastitis, and the usefulness of diffusion-weighted magnetic resonance imaging (DW-MRI) in distinguishing idiopathic granulomatous mastitis (IGM) from malignant breast lesions. MATERIAL AND METHODS: A total of 37 women (mean age 36 + 8; range 20-67 years) with histopathologic diagnoses of idiopathic granulomatous mastitis were enrolled in the study. Five patients had bilateral IGM, which were evaluated as ten cases...
July 12, 2016: La Radiologia Medica
Yun Hee Cho, Kyu Ran Cho, Eun Kyung Park, Bo Kyoung Seo, Ok Hee Woo, Sung Bum Cho, Jeoung Won Bae
BACKGROUND: In preoperative assessment of breast cancer, MRI has been shown to identify more additional breast lesions than are detectable using conventional imaging techniques. The characterization of additional lesions is more important than detection for optimal surgical treatment. Additional breast lesions can be included in focus, mass, and non-mass enhancement (NME) on MRI. According to the fifth edition of the breast imaging reporting and data system (BI-RADS®), which includes several changes in the NME descriptors, few studies to date have evaluated NME in preoperative assessment of breast cancer...
January 2016: Iranian Journal of Radiology: a Quarterly Journal Published By the Iranian Radiological Society
Peng Gu, Won-Mean Lee, Marilyn A Roubidoux, Jie Yuan, Xueding Wang, Paul L Carson
Segmentation of an ultrasound image into functional tissues is of great importance to clinical diagnosis of breast cancer. However, many studies are found to segment only the mass of interest and not all major tissues. Differences and inconsistencies in ultrasound interpretation call for an automated segmentation method to make results operator-independent. Furthermore, manual segmentation of entire three-dimensional (3D) ultrasound volumes is time-consuming, resource-intensive, and clinically impractical. Here, we propose an automated algorithm to segment 3D ultrasound volumes into three major tissue types: cyst/mass, fatty tissue, and fibro-glandular tissue...
February 2016: Ultrasonics
Lucia Manganaro, Ilaria D'Ambrosio, Silvia Gigli, Francesca Di Pastena, Guglielmo Giraldi, Stefano Tardioli, Marialuisa Framarino, Lucio Maria Porfiri, Laura Ballesio
PURPOSE: Assessing the role of breast MRI compared to galactography in patients with unilateral bloody or serous-bloody nipple discharge. MATERIALS AND METHODS: Retrospective study including 53 unilateral discharge patients who performed galactography and MRI. We evaluated the capability of both techniques in identifying pathology and distinguishing between nonmalignant and malignant lesions. Lesions BIRADS 1/2 underwent follow-up, while the histological examination after surgery has been the gold standard to assess pathology in lesions BIRADS 3/4/5...
2015: BioMed Research International
Albert Gubern-Mérida, Robert Martí, Jaime Melendez, Jakob L Hauth, Ritse M Mann, Nico Karssemeijer, Bram Platel
Dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) is increasingly being used for the detection and diagnosis of breast cancer. Compared to mammography, DCE-MRI provides higher sensitivity, however its specificity is variable. Moreover, DCE-MRI data analysis is time consuming and depends on reader expertise. The aim of this work is to propose a novel automated breast cancer localization system for DCE-MRI. Such a system can be used to support radiologists in DCE-MRI analysis by marking suspicious areas...
February 2015: Medical Image Analysis
Fatima Nayeem, Hyunsu Ju, Donald G Brunder, Manubai Nagamani, Karl E Anderson, Tuenchit Khamapirad, Lee-Jane W Lu
Women with high breast density (BD) have a 4- to 6-fold greater risk for breast cancer than women with low BD. We found that BD can be easily computed from a mathematical algorithm using routine mammographic imaging data or by a curve-fitting algorithm using fat and nonfat suppression magnetic resonance imaging (MRI) data. These BD measures in a strictly defined group of premenopausal women providing both mammographic and breast MRI images were predicted as well by the same set of strong predictor variables as were measures from a published laborious histogram segmentation method and a full field digital mammographic unit in multivariate regression models...
2014: International Journal of Breast Cancer
Jacob Levman, Ellen Warner, Petrina Causer, Anne Martel
Cancer screening with magnetic resonance imaging (MRI) is currently recommended for very high risk women. The high variability in the diagnostic accuracy of radiologists analyzing screening MRI examinations of the breast is due, at least in part, to the large amounts of data acquired. This has motivated substantial research towards the development of computer-aided diagnosis (CAD) systems for breast MRI which can assist in the diagnostic process by acting as a second reader of the examinations. This retrospective study was performed on 184 benign and 49 malignant lesions detected in a prospective MRI screening study of high risk women at Sunnybrook Health Sciences Centre...
October 2014: Journal of Digital Imaging: the Official Journal of the Society for Computer Applications in Radiology
Joo Yeon Kim, Yun Ju Kim, Sung Hun Kim, Bong Joo Kang, Byung Joo Song
Breast cancer is rare in children and adolescents. In particular, there are very few cases of invasive ductal carcinoma in childhood. We report a case of invasive ductal carcinoma of the breast in a 14-year-old girl presenting as a palpable mass. While the tumor demonstrated a relatively benign appearance on ultrasound, magnetic resonance imaging revealed typical malignant features. Several polymorphisms of single nucleotide variation were observed on gene analysis. The patient underwent breast conserving surgery and received subsequent concurrent chemo-radiation therapy...
November 2014: Pediatric Radiology
Young Ju Lee, Bo Bae Choi, Kwang Sun Suh
BACKGROUND: Invasive cribriform carcinoma (ICC) of the breast is a rare type of invasive carcinoma which shows a favorable prognosis and a lower frequency of axillary nodal metastases. Few imaging findings related to ICC have been reported. PURPOSE: To evaluate imaging findings with multiple imaging techniques in ICC of the breast. MATERIAL AND METHODS: Twenty-eight cases of histopathologically proven ICC of the breast were gathered for this study...
June 2015: Acta Radiologica
Hongmin Cai, Yanxia Peng, Caiwen Ou, Minsheng Chen, Li Li
PURPOSE: Dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) is increasingly used for breast cancer diagnosis as supplementary to conventional imaging techniques. Combining of diffusion-weighted imaging (DWI) of morphology and kinetic features from DCE-MRI to improve the discrimination power of malignant from benign breast masses is rarely reported. MATERIALS AND METHODS: The study comprised of 234 female patients with 85 benign and 149 malignant lesions...
2014: PloS One
Kumi Hasegawa, Toshihiro Matsui, Haruhiko Aoyagi, Tsuyoshi Yoshida, Jun Kaneko, Shizuaki Maejima
We report a case of a 55-year-old woman who underwent mastectomy and axillary lymph node dissection for right breast cancer( T2N1cM0) 7 years previously. She had been experiencing chest pain for 1 year. Ultrasonography( US) showed a low echoic mass, 1 cm in diameter, near the rib in the right breast (class 5).Magnetic resonance imaging (MRI) and positron emission tomography( PET)-computed tomography( CT) scans revealed an 8-cm wide, segmentally enhancing soft tissue lesion and enhanced lymph nodes at the right edge of the sternum...
November 2013: Gan to Kagaku Ryoho. Cancer & Chemotherapy
Liqiong Lv, Yun Zhao, Hui Liu, Zhongyi Peng
A 41-year-old female was admitted into hospital due to recurrent abdominal pain with bloating. An enteroscopy was carried out and stenosis in the lower jejunal lumen was identified. This led to a diagnosis of small bowel obstruction caused by inflammation. During the laparotomy, the resection and anastomosis of a narrow segment of small intestine was performed. In combination with the results of immunohistochemical analysis, the postoperative pathology indicated the presence of a poorly differentiated/undifferentiated carcinoma of the small intestine, which was considered to have arisen from breast cancer...
September 2013: Experimental and Therapeutic Medicine
Mai Okubo, Keiichiro Tada, Takayoshi Niwa, Kotoe Nishioka, Eiichi Tsuji, Toshihisa Ogawa, Yasuyuki Seto
BACKGROUND: The management of cancer in the axillary area depends on the etiology of the tumor. CASE REPORT: A 37-year-old woman presented with a 2 cm mass in the axillary fossa. Core needle biopsy revealed adenocarcinoma. There were no abnormal breast findings on physical examination, mammography, or ultrasonography. However, enhanced magnetic resonance imaging (MRI) and positron emission tomography (PET) showed a segmentally-distributed, abnormal area in the upper-outer quadrant, continuous with the axillary mass...
2013: World Journal of Surgical Oncology
Krish Ramachandaran, Sam Aziz, Stephen Phillips, Salman Gohar
SESSION TYPE: Cardiovascular Student/Resident Case Report Posters IPRESENTED ON: Tuesday, October 23, 2012 at 01:30 PM - 02:30 PMINTRODUCTION: Neoplastic metastases to the heart and pericardium are more common than primary cardiac tumors. Cardiac metastasis occurs in as many as 22-31% of lung cancer patients. The majority experience pericardial metastasis while myocardial metastasis is described in 5.3-10.6% of patients. Often silent, these are rarely recognized prior to postmortem examination. ECG changes are rare and usually demonstrate non-specific ST and T wave abnormalities...
October 1, 2012: Chest
G Semprini, F Cattin, M Riccio, C Cedolini, P C Parodi
AIM: There is an increased expectation from breast cancer patients to retain their "normal breast appearance". To help to achieve this expectation, many radiologic exams have been created to get the exact extension and position of the tumor. MRI is effective to obtain correct information about neoplasms, especially those with shaded edges, like DCIS. MRI might change the surgical project, thus avoiding second operations for cancer relapses. METHODS: We have performed MRI to all the patients except those with big lesions or adypous breasts...
February 2013: Minerva Chirurgica
Misato Iizuka, Katsuhisa Enomoto, Kenichi Sakurai
Here, we report the case of a 40-year-old woman who was discovered upon examination to have a lump in her left breast. Breast ultrasonography revealed a hypoechoic mass of size 2.5×2.5 cm, shaped irregularly with fine calcification in the left DE area. A needle biopsy was performed and the resulting pathological diagnosis was invasive cancer(apocrine carcinoma, T2N0M0, Stage IIA),negative for estrogen receptor (ER), progesterone receptor (PgR), and human epidermal growth factor receptor type 2(HER2). Neoadjuvant chemotherapy was then performed with docetaxel/cyclophosphamide (TC)(4 courses) and epirubicin/cyclophosphamide (EC)(4 courses), after which ultrasonography revealed a significant reduction in mass, with a hypoechoic area of 1...
November 2012: Gan to Kagaku Ryoho. Cancer & Chemotherapy
Andrew X Zhu, Jennifer J Knox
Presentation of the Case A 37-year-old woman presented at 35 weeks of gestation with her third child with failure to adequately gain weight and was noted by her obstetrician to have delay in the growth of her baby. Ultrasound of the abdomen incidentally revealed the presence of a liver lesion. After additional evaluation, she ultimately delivered her daughter at 36 weeks uneventfully. She subsequently underwent additional evaluation. Liver magnetic resonance imaging (MRI) revealed a 5-cm solitary solid mass in segment 4A of the liver, concerning for malignancy...
2012: Oncologist
Maki Amano, Kanako Ogura, Yutaka Ozaki, Mitsukuni Tamai, Toshiaki Kitabatake, Minoru Fujisawa, Kuniaki Kojima
Primary small cell carcinoma of the breast is a rare breast cancer. We report two cases of this entity showing a non-mass-like pattern on multimodality images and histopathology. Both women presented with a breast mass, and one had axillary lymphadenopathy. Both cases revealed fine calcification on mammography (MMG) and an irregularly shaped, hypoechoic lesion on ultrasonography. Computed tomography (CT) and magnetic resonance imaging (MRI) showed non-mass-like enhancement in both cases. Dynamic MRI showed medium initial enhancement followed by persistent delayed enhancement in one patient, whereas rapid initial enhancement with plateau delayed enhancement was observed in the other...
July 2015: Breast Cancer: the Journal of the Japanese Breast Cancer Society
Yachun Pang, Li Li, Wenyong Hu, Yanxia Peng, Lizhi Liu, Yuanzhi Shao
This paper presents a novel two-step approach that incorporates fuzzy c-means (FCMs) clustering and gradient vector flow (GVF) snake algorithm for lesions contour segmentation on breast magnetic resonance imaging (BMRI). Manual delineation of the lesions by expert MR radiologists was taken as a reference standard in evaluating the computerized segmentation approach. The proposed algorithm was also compared with the FCMs clustering based method. With a database of 60 mass-like lesions (22 benign and 38 malignant cases), the proposed method demonstrated sufficiently good segmentation performance...
2012: Computational and Mathematical Methods in Medicine
Yeong Yi An, Sung Hun Kim, Bong Joo Kang, A Won Lee, Byung Joo Song
BACKGROUND: The purpose of this study was to compare the accuracy of volumetric (3D) measurements with that of unidimensional (1D) measurements by response evaluation criteria in solid tumors 1.1 (RECIST 1.1) in patients with breast cancer before and after neoadjuvant chemotherapy. METHODS: The study included 48 patients with breast cancer who underwent neoadjuvant chemotherapy. Dynamic contrast-enhanced magnetic resonance imaging was performed before the first cycle of chemotherapy and after the completion of the planned chemotherapy...
May 2014: Breast Cancer: the Journal of the Japanese Breast Cancer Society
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