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Breast cancer, MRI, imaging processing

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https://www.readbyqxmd.com/read/28102529/recovery-from-chemotherapy-induced-white-matter-changes-in-young-breast-cancer-survivors
#1
Thibo Billiet, Louise Emsell, Mathieu Vandenbulcke, Ronald Peeters, Daan Christiaens, Alexander Leemans, Wim Van Hecke, Ann Smeets, Frederic Amant, Stefan Sunaert, Sabine Deprez
In a previous longitudinal diffusion tensor imaging (DTI) study, we observed cerebral white matter (WM) alterations (reduced fractional anisotropy (FA)) related to decreased cognitive performance 3-5 months after chemotherapy-treatment (t2) when compared to baseline (t1) (Deprez et al. in Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology, 30(3), 274-281. doi:10.1200/JCO.2011.36.8571, 2012). The current study investigates the evolution and the nature of these previously observed microstructural changes...
January 19, 2017: Brain Imaging and Behavior
https://www.readbyqxmd.com/read/28048528/we-h-206-01-photoacoustic-tomography-multiscale-imaging-from-organelles-to-patients-by-ultrasonically-beating-the-optical-diffusion-limit
#2
L Wang
: Lihong V. Wang: Photoacoustic tomography (PAT), combining non-ionizing optical and ultrasonic waves via the photoacoustic effect, provides in vivo multiscale functional, metabolic, and molecular imaging. Broad applications include imaging of the breast, brain, skin, esophagus, colon, vascular system, and lymphatic system in humans or animals. Light offers rich contrast but does not penetrate biological tissue in straight paths as x-rays do. Consequently, high-resolution pure optical imaging (e...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28047869/we-h-206-02-recent-advances-in-multi-modality-molecular-imaging-of-small-animals
#3
B Tsui
: Lihong V. Wang: Photoacoustic tomography (PAT), combining non-ionizing optical and ultrasonic waves via the photoacoustic effect, provides in vivo multiscale functional, metabolic, and molecular imaging. Broad applications include imaging of the breast, brain, skin, esophagus, colon, vascular system, and lymphatic system in humans or animals. Light offers rich contrast but does not penetrate biological tissue in straight paths as x-rays do. Consequently, high-resolution pure optical imaging (e...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28047476/su-f-i-16-short-breast-mri-with-high-resolution-t2-weighted-and-dynamic-contrast-enhanced-t1-weighted-images
#4
J Ma, J Son, B Arun, J Hazle, K Hwang, K Wang, E Bayram, J Madewell, W Yang, B Dogan
PURPOSE: To develop and demonstrate a short breast (sb) MRI protocol that acquires both T2-weighted and dynamic contrast-enhanced T1-weighted images in approximately ten minutes. METHODS: The sb-MRI protocol consists of two novel pulse sequences. The first is a flexible fast spin-echo triple-echo Dixon (FTED) sequence for high-resolution fat-suppressed T2-weighted imaging, and the second is a 3D fast dual-echo spoiled gradient sequence (FLEX) for volumetric fat-suppressed T1-weighted imaging before and post contrast agent injection...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28047205/we-h-206-03-promises-and-challenges-of-benchtop-x-ray-fluorescence-ct-xfct-for-quantitative-in-vivo-imaging
#5
S Cho
: Lihong V. Wang: Photoacoustic tomography (PAT), combining non-ionizing optical and ultrasonic waves via the photoacoustic effect, provides in vivo multiscale functional, metabolic, and molecular imaging. Broad applications include imaging of the breast, brain, skin, esophagus, colon, vascular system, and lymphatic system in humans or animals. Light offers rich contrast but does not penetrate biological tissue in straight paths as x-rays do. Consequently, high-resolution pure optical imaging (e...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28046461/we-h-206-00-advances-in-preclinical-imaging
#6
Patrick La Riviere
: Lihong V. Wang: Photoacoustic tomography (PAT), combining non-ionizing optical and ultrasonic waves via the photoacoustic effect, provides in vivo multiscale functional, metabolic, and molecular imaging. Broad applications include imaging of the breast, brain, skin, esophagus, colon, vascular system, and lymphatic system in humans or animals. Light offers rich contrast but does not penetrate biological tissue in straight paths as x-rays do. Consequently, high-resolution pure optical imaging (e...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/27805423/the-potential-of-multiparametric-mri-of-the-breast
#7
REVIEW
Katja Pinker, Thomas H Helbich, Elizabeth A Morris
MRI is an essential tool in breast imaging, with multiple established indications. Dynamic contrast-enhanced MRI (DCE-MRI) is the backbone of any breast MRI protocol and has an excellent sensitivity and good specificity for breast cancer diagnosis. DCE-MRI provides high-resolution morphological information, as well as some functional information about neoangiogenesis as a tumour-specific feature. To overcome limitations in specificity, several other functional MRI parameters have been investigated and the application of these combined parameters is defined as multiparametric MRI (mpMRI) of the breast...
January 2017: British Journal of Radiology
https://www.readbyqxmd.com/read/27569368/computer-based-automated-estimation-of-breast-vascularity-and-correlation-with-breast-cancer-in-dce-mri-images
#8
Spiros A Kostopoulos, Katerina G Vassiou, Eleftherios N Lavdas, Dionisis A Cavouras, Ioannis K Kalatzis, Pantelis A Asvestas, Dimitrios L Arvanitis, Ioannis V Fezoulidis, Dimitris T Glotsos
Dynamic contrast enhanced magnetic resonance imaging (DCE-MRI) with gadolinium constitutes one of the most promising protocols for boosting up the sensitivity in breast cancer detection. The aim of this study was twofold: first to design an image processing methodology to estimate the vascularity of the breast region in DCE-MRI images and second to investigate whether the differences in the composition/texture and vascularity of normal, benign and malignant breasts may serve as potential indicators regarding the presence of the disease...
August 26, 2016: Magnetic Resonance Imaging
https://www.readbyqxmd.com/read/27456031/how-i-report-breast-magnetic-resonance-imaging-studies-for-breast-cancer-staging-and-screening
#9
Sarah Vinnicombe
Magnetic resonance imaging (MRI) of the breast is the most sensitive imaging technique for the diagnosis and local staging of primary breast cancer and yet, despite the fact that it has been in use for 20 years, there is little evidence that its widespread uncritical adoption has had a positive impact on patient-related outcomes.This has been attributed previously to the low specificity that might be expected with such a sensitive modality, but with modern techniques and protocols, the specificity and positive predictive value for malignancy can exceed that of breast ultrasound and mammography...
July 25, 2016: Cancer Imaging: the Official Publication of the International Cancer Imaging Society
https://www.readbyqxmd.com/read/27346235/executive-function-alternations-of-breast-cancer-patients-after-chemotherapy-evidence-from-resting-state-functional-mri
#10
Lu Wang, Yunwen Yan, Xiaofeng Wang, Longxiang Tao, Quan Chen, Yunpeng Bian, Xiaoxuan He, Yikang Liu, Weiping Ding, Yongqiang Yu, Bensheng Qiu
RATIONALE AND OBJECTIVES: Chemotherapy has many side effects on breast cancer patients, including cognition and other brain functions impairment, which can be studied using functional magnetic resonance imaging (fMRI). Our study aimed at investigating the executive function alternations of breast cancer patients after chemotherapy using resting-state fMRI. MATERIALS AND METHODS: This study included 32 breast cancer patients (BC group) and 24 control subjects (HC group)...
October 2016: Academic Radiology
https://www.readbyqxmd.com/read/27339420/application-prospective-of-nanoprobes-with-mri-and-fi-dual-modality-imaging-on-breast-cancer-stem-cells-in-tumor
#11
REVIEW
Hetao Chen, Yu Wang, Tong Wang, Dongxing Shi, Zengrong Sun, Chunhui Xia, Baiqi Wang
Breast cancer (BC) is a serious disease to threat lives of women. Numerous studies have proved that BC originates from cancer stem cells (CSCs). But at present, no one approach can quickly and simply identify breast cancer stem cells (BCSCs) in solid tumor. Nanotechnology is probably able to realize this goal. But in study process, scientists find it seems that nanomaterials with one modality, such as magnetic resonance imaging (MRI) or fluorescence imaging (FI), have their own advantages and drawbacks. They cannot meet practical requirements in clinic...
June 23, 2016: Journal of Nanobiotechnology
https://www.readbyqxmd.com/read/27335532/a-utility-cost-analysis-of-breast-cancer-risk-prediction-algorithms
#12
Craig K Abbey, Yirong Wu, Elizabeth S Burnside, Adam Wunderlich, Frank W Samuelson, John M Boone
Breast cancer risk prediction algorithms are used to identify subpopulations that are at increased risk for developing breast cancer. They can be based on many different sources of data such as demographics, relatives with cancer, gene expression, and various phenotypic features such as breast density. Women who are identified as high risk may undergo a more extensive (and expensive) screening process that includes MRI or ultrasound imaging in addition to the standard full-field digital mammography (FFDM) exam...
February 27, 2016: Proceedings of SPIE
https://www.readbyqxmd.com/read/27108218/abbreviated-combined-mr-protocol-a-new-faster-strategy-for-characterizing-breast-lesions
#13
Marco Moschetta, Michele Telegrafo, Leonarda Rella, Amato Antonio Stabile Ianora, Giuseppe Angelelli
BACKGROUND: The use of an abbreviated magnetic resonance (MR) protocol has been recently proposed for cancer screening. The aim of our study is to evaluate the diagnostic accuracy of an abbreviated MR protocol combining short TI inversion recovery (STIR), turbo-spin-echo (TSE)-T2 sequences, a pre-contrast T1, and a single intermediate (3 minutes after contrast injection) post-contrast T1 sequence for characterizing breast lesions. MATERIALS AND METHODS: A total of 470 patients underwent breast MR examination for screening, problem solving, or preoperative staging...
June 2016: Clinical Breast Cancer
https://www.readbyqxmd.com/read/27091490/clinically-mild-encephalitis-encephalopathy-with-a-reversible-splenial-lesion-caused-by-methicillin-sensitive-staphylococcus-aureus-bacteremia-with-toxic-shock-syndrome-a-case-report
#14
Koki Kosami, Tsuneaki Kenzaka, Yuka Sagara, Kensuke Minami, Masami Matsumura
BACKGROUND: Clinically mild encephalitis/encephalopathy with a reversible splenial lesion (MERS) is a mild encephalopathy caused by various pathological processes, but encephalopathy due to bacteria is rare. CASE PRESENTATION: We report the case of a 45-year-old Japanese woman who on receiving chemotherapy for advanced breast cancer developed an altered mental status and dysarthria soon after fever from infection of a subcutaneous implantable port. Staphylococcus aureus was detected in her blood cultures...
April 18, 2016: BMC Infectious Diseases
https://www.readbyqxmd.com/read/26949063/pseudoangiomatous-stromal-hyperplasia-of-the-breast-multimodality-review-with-pathologic-correlation
#15
Sean D Raj, Vivek G Sahani, Beatriz E Adrada, Marion E Scoggins, Constance T Albarracin, Piyanoot Woodtichartpreecha, Flavia E Posleman Monetto, Gary J Whitman
Pseudoangiomatous stromal hyperplasia (PASH) is a rare benign breast condition. PASH is thought to be hormonally responsive, and it is usually identified in premenopausal and perimenopausal women. PASH may also be seen in postmenopausal woman on hormone replacement therapy (HRT). Approximately 53% of patients with PASH present with abnormalities on screening mammography, and 44% of patients with PASH present with palpable abnormalities. On imaging studies, PASH appears similar to fibroadenomas. On mammography, PASH is usually seen as a noncalcified, circumscribed mass...
February 2, 2016: Current Problems in Diagnostic Radiology
https://www.readbyqxmd.com/read/26941084/functional-imaging-of-the-angiogenic-switch-in-a-transgenic-mouse-model-of-human-breast-cancer-by-dynamic-contrast-enhanced-magnetic-resonance-imaging
#16
Lorena Consolino, Dario Livio Longo, Walter Dastrù, Juan Carlos Cutrin, Daniela Dettori, Stefania Lanzardo, Salvatore Oliviero, Federica Cavallo, Silvio Aime
Tumour progression depends on several sequential events that include the microenvironment remodelling processes and the switch to the angiogenic phenotype, leading to new blood vessels recruitment. Non-invasive imaging techniques allow the monitoring of functional alterations in tumour vascularity and cellularity. The aim of this work was to detect functional changes in vascularisation and cellularity through Dynamic Contrast Enhanced (DCE) and Diffusion Weighted (DW) Magnetic Resonance Imaging (MRI) modalities during breast cancer initiation and progression of a transgenic mouse model (BALB-neuT mice)...
July 15, 2016: International Journal of Cancer. Journal International du Cancer
https://www.readbyqxmd.com/read/26614888/characterizing-the-mammography-technologist-workforce-in-north-carolina
#17
Louise M Henderson, Mary W Marsh, Thad Benefield, Elizabeth Pearsall, Danielle Durham, Bruce F Schroeder, J Michael Bowling, Cheryl A Viglione, Bonnie C Yankaskas
PURPOSE: Mammography technologists' level of training, years of experience, and feedback on technique may play an important role in the breast-cancer screening process. However, information on the mammography technologist workforce is scant. METHODS: In 2013, we conducted a survey mailed to 912 mammography technologists working in 224 facilities certified by the Mammography Quality Standards Act in North Carolina. Using standard survey methodology, we developed and implemented a questionnaire on the education and training, work experiences, and workplace interactions of mammography technologists...
December 2015: Journal of the American College of Radiology: JACR
https://www.readbyqxmd.com/read/26511652/fluorine-19-labeling-of-stromal-vascular-fraction-cells-for-clinical-imaging-applications
#18
Laura C Rose, Deepak K Kadayakkara, Guan Wang, Amnon Bar-Shir, Brooke M Helfer, Charles F O'Hanlon, Dara L Kraitchman, Ricardo L Rodriguez, Jeff W M Bulte
UNLABELLED: Stromal vascular fraction (SVF) cells are used clinically for various therapeutic targets. The location and persistence of engrafted SVF cells are important parameters for determining treatment failure versus success. We used the GID SVF-1 platform and a clinical protocol to harvest and label SVF cells with the fluorinated ((19)F) agent CS-1000 as part of a first-in-human phase I trial (clinicaltrials.gov identifier NCT02035085) to track SVF cells with magnetic resonance imaging during treatment of radiation-induced fibrosis in breast cancer patients...
December 2015: Stem Cells Translational Medicine
https://www.readbyqxmd.com/read/26385836/clinical-abnormalities-of-the-nipple-areola-complex-the-role-of-imaging
#19
D Geffroy, I Doutriaux-Dumoulins
Clinical examination of the nipple is part of normal breast screening procedures. Abnormal processes of benign or malignant nature may be reflected by erythema, erosion, swelling or acquired inversion. In patients presenting with a persistent unilateral nipple lesion, it is advisable to collect a sample to exclude Paget's disease of the nipple, a rare form of ductal carcinoma in situ (DCIS). Imaging should be performed to detect breast cancer, which is found in more than 80% of cases, and determine its possible multifocal nature...
October 2015: Diagnostic and Interventional Imaging
https://www.readbyqxmd.com/read/26372221/diagnostic-strategy-for-the-assessment-of-axillary-lymph-node-status-in-breast-cancer
#20
F Maxwell, C de Margerie Mellon, M Bricout, E Cauderlier, M Chapelier, M Albiter, P Bourrier, M Espié, E de Kerviler, C de Bazelaire
The nodal status in breast cancer is a major prognostic factor in terms of survival. It also plays a role in the therapeutic decision-making process. Therefore, the evaluation of lymph node involvement in breast cancer is imperative in establishing a personalized treatment scheme. The sentinel lymph node procedure has proved successful for small breast tumors (T1-T2), limiting axillary lymphadenectomy and its side effects without changing overall survival. Even so, a substantial number of women must undergo axillary lymphadenectomy during a second surgery when the analysis of the sentinel node discloses major nodal involvement...
October 2015: Diagnostic and Interventional Imaging
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